Campus Event Calendar
Event Entry
New for: D1, D2, D3, D4, D5
What and Who
Analysis of protein binding pocket flexibility
Igor Trajkovski
IMPRS
IMPRS Masters' Lunch
AG 1, AG 2, AG 3, AG 4, AG 5
AG Audience
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Date, Time and Location
Tuesday, 25 May 2004
13:00
60 Minutes
46.1 - MPII
024
Saarbrücken
Abstract
Ligand binding may involve a wide range of structural changes in the
receptor protein, from group movement of entire domains to small
side-chain
rearrangements in the binding pocket residues. In this talk I review
protein structures, energy models, classical rigid docking problem,
and how we can model and introduce protein binding pockets flexibility.
All these models strive to balance an improvement in the accuracy of the
receptor protein, from group movement of entire domains to small
side-chain
rearrangements in the binding pocket residues. In this talk I review
protein structures, energy models, classical rigid docking problem,
and how we can model and introduce protein binding pockets flexibility.
All these models strive to balance an improvement in the accuracy of the
binding predictions with an increase in computational cost.
Contact
Kerstin Meyer-Ross
0681 - 9325 226
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Christine Kiesel, 06/22/2004 10:14
Christine Kiesel, 05/24/2004 14:37
Christine Kiesel, 05/10/2004 12:50
Christine Kiesel, 05/10/2004 12:48 -- Created document.
Christine Kiesel, 05/24/2004 14:37
Christine Kiesel, 05/10/2004 12:50
Christine Kiesel, 05/10/2004 12:48 -- Created document.