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What and Who

Transcription factor binding sites and chromatin modifications point at two classes of human promoters

Prof. Dr. Martin Vingron
Max Planck Institute for Molecular Genetics
AG3 Talk
AG 1, AG 2, AG 3, AG 4, AG 5, SWS, RG1, MMCI  
MPI Audience
English

Date, Time and Location

Wednesday, 9 June 2010
17:00
60 Minutes
E2 1 (ZBI)
R001
Saarbrücken

Abstract

Starting with a biophysically motivated method of transcription factor binding site prediction, this talk shall highlight the differences between promoters with high and low CpG contents. The two classes of promoters display different features when it comes to binding sites and tissue specific regulation.The dichotomy is further supported by an analysis of histone modifications in the promoters,which also shows different patterns for the two groups.

Contact

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Ruth Schneppen-Christmann, 06/09/2010 16:37
Ruth Schneppen-Christmann, 06/08/2010 12:17 -- Created document.