# | Y |  | Author/Editor | | Title | |
11 |
 | 2014 |
|  |
7 |
|
|  |
| | | Pironti, Alejandro
Lengauer, Thomas
Pfeifer, Nico | | Simulation of Sanger-sequencing errors in the context of genotypic tropism determination
In: Antiviral Therapy, A81 |  |
 |  |  | Pironti, Alejandro
Pfeifer, Nico
Kaiser, Rolf
Walter, Hauke
Lengauer, Thomas | | Accurate prediction of drug-exposure without using established drug-resistance mutations
In: Antiviral Therapy, A75 |  |
| | | Pironti, Alejandro
Pfeifer, Nico
Kaiser, Rolf
Walter, Hauke
Lengauer, Thomas | | Improved HIV-1 drug-exposure reconstruction with linear support vector machines
In: Reviews in Antiviral Therapy & Infectious Diseases, 67 |  |
 |  |  | Pironti, Alejandro
Pfeifer, Nico
Kaiser, Rolf
Walter, Hauke
Lengauer, Thomas | | Improved therapy-success prediction with GSS estimated from clinical HIV-1 sequences
In: Abstract Supplement of the HIV Drug Therapy Glasgow Congress 2014, 155 |  |
| | | Pironti, Alejandro
Pfeifer, Nico
Lengauer, Thomas | | Accurate prediction of drug-exposure without using established drug-resistance mutations
In: Antiviral Therapy, A75 |  |
 |  |  | Pironti, Alejandro
Pfeifer, Nico
Lengauer, Thomas | | Improved HIV-1 drug-exposure reconstruction with linear support vector machines
In: Reviews in Antiviral Therapy & Infectious Diseases, 67 |  |
| | | Pironti, Alejandro
Sierra, Saleta
Kaiser, Rolf
Lengauer, Thomas
Pfeifer, Nico | | Simulation of Sanger-sequencing errors in the context of genotypic tropism determination
In: Antiviral Therapy, A81 |  |
2 |
|
|  |
| | | Lawyer, Glenn | | COMET: Adaptive context-based modeling for ultrafast HIV-1 subtype identification.
In: Nucleic Acids Research [42], e144 |  |
 |  |  | Maurer, Felix
Hauschild, Anne-Christin
Eisinger, Kathrin
Baumbach, Jan
Mayor, Arno
Baumbach, Jörg Ingo | | MIMA - A software for analyte identification in MCC/IMS chromatograms by mapping accompanying GC/MS measurements
In: International Journal for Ion Mobility Spectrometry [?], ? |  |
2 |
|
 | Unpublished/Draft |
|  |
 |  |  | Eckel, Sandrah
Baumbach, Jan
Hauschild, Anne-Christin | | On the importance of statistics in breath analysis - Hope or curse? |  |
| | | Smolinska, Agnieszka
Hauschild, Anne-Christin
Fijten, Rianne
Dallinga, Jan
Baumbach, Jan
van Schooten, Frederik | | Current breathomics – A review on data pre-processing techniques and machine learning in metabolomics breath analysis |  |
31 |
|  |
4 |
|
 | Poster |
|  |
 |  |  | Kalaghatgi, Prabhav
Lawyer, Glenn | | Inter-country mixing in HIV transmission clusters: a pan-European phylodynamics study
In: Abstract Book 11th European HIV & Hepatitis Workshop, 9 |  |
| | | Pfeifer, Nico
Lengauer, Thomas | | Association Between HIV-1 Coreceptor Usage and Resistance to Some Broadly Neutralizing Antibodies
In: Proceedings of the AIDS Vaccine Conference 2013, A-1-A-208 |  |
 |  |  | Pironti, Alejandro
Lengauer, Thomas
Pfeifer, Nico | | Effects of sequencing errors on geno2pheno[coreceptor] predictions
In: Abstract Book 11th European Meeting on HIV & Hepatitis, 23-24 |  |
| | | Pironti, Alejandro
Lengauer, Thomas
Pfeifer, Nico | | In silico analysis of the effects of sequencing errors on geno2pheno[coreceptor]
In: Abstract Book of the International Workshop on HIV&Hepatitis Virus, A142 |  |
22 |
|
|  |
| | | Beggel, Bastian
Münk, C.
Däumer, M.
Hauck, K.
Häussinger, D.
Lengauer, Thomas
Ehrhardt, A. | | Full genome ultra-deep pyrosequencing associates G-to-A-hypermutation of the hepatitis B virus genome with the natural progression of hepatitis B
In: Journal of Viral Hepatitis [12], 882-889 |  |
 |  |  | Bhadra, T.
Battacharya, M.
Feuerbach, L.
Lengauer, Thomas
Bandyopadhyay, S. | | DNA Methylation Patterns Facilitate the Identification of Transcription Start Sites: A Brain-specofoc Study
In: PLOSONE [8], xx |  |
| | | Bozek, K.
Lengauer, Thomas
Sierra, S.
Kaiser, Rolf
Domingues, F.S. | | Analysis of physicochemical and structural properties determining HIV-1 coreceptor usage
In: PLoS Computational Biology [x], x |  |
 |  |  | Dietz, J.
Schelhorn, Sven-Eric
Fitting, D.
Mihm, U.
Susser, S.
Welker, M.-W.
Füller, C.
Däumer, M.
Teuber, G.
Wedemeyer, H.
Berg, T.
Lengauer, Thomas
Z., Stefan
Herrmann, E.
Sarrazin, C. | | Deep sequencing reveals mutagenic effects of ribavirin during monotherapy of HCV genotype 1-infected patients
In: Journal of Virology [87], 6172-6181 |  |
| | | Ellinghaus, David
Zhang, Hu
Zeissig, Sebastian
Lipinski, Simone
Till, Andreas
Jiang, Tao
Stade, Björn
Bromberg, Yana
Ellinghaus, Eva
Keller, Andreas
Rivas, Manuel A.
Skieceviciene, Jurgita
Doncheva, Nadezhda T.
Liu, Xiao
Liu, Qing
Jiang, Fuman
Forster, Michael
Mayr, Gabriele
Albrecht, Mario
Häsler, Robert
Boehm, Bernhard O.
Goodall, Jane
Berzuini, Carlo R.
Lee, James
Andersen, Vibeke
Vogel, Ulla
Kupcinskas, Limas
Kayser, Manfred
Krawczak, Michael
Nikolaus, Susanna
Weersma, Rinse K.
Ponsioen, Cyriel Y.
Sans, Miquel
Wijmenga, Cisca
Strachan, David P.
McArdle, Wendy L.
Vermeire, Séverine
Rutgeerts, Paul
Sanderson, Jeremy D.
Mathew, Christopher G.
Vatn, Morten H.
Wang, Jun
Nöthen, Markus M.
Duerr, Richard H.
Büning, Carsten
Brand, Stephan
Glas, Jürgen
Winkelmann, Juliane
Illig, Thomas
Latiano, Anna
Annese, Vito
Halfvarson, Jonas
D'Amato, Mauro
Daly, Mark J.
Nothnagel, Michael
Karlsen, Tom H.
Subramani, Suresh
Rosenstiel, Philip
Schreiber, Stefan
Parkes, Miles
Franke, Andre | | Association between variants of PRDM1 and NDP52 and Crohn's disease, based on exome sequencing and functional studies
In: Gastroenterology [145], 339-347 |  |
 |  |  | Halachev, Konstantin
Bast, H.
Lengauer, Thomas
Bock, Christoph | | Interactive exploration of large genome and epigenome datasets in real time
In: Genome Biology [13], xx |  |
| | | Kacprowski, Tim
Doncheva, Nadezhda T.
Albrecht, Mario |  | NetworkPrioritizer: a versatile tool for network-based prioritization of candidate disease genes or other molecules
In: Bioinformatics [29], 1471-1473 |  |
 |  |  | Kalinina, Olga
Pfeifer, Nico
Lengauer, Thomas | | Modelling binding between CCR5 and CXCR4 receptors and their ligands suggests the surface electrostatic potential of the co-receptor to be a key player in the HIV-1 tropism
In: Retrovirology [10], 130 |  |
| | | Le, Hai-Son
Schulz, Marcel Holger
McCauley, Brenna MM
Hinman, Veronica F
Bar-Joseph, Ziv | | Probabilistic error correction for RNA sequencing
In: Nucleic Acids Researcb [41], e109 |  |
 |  |  | Liu, Jimmy Z.
Hov, Johannes Roksund
Folseraas, Trine
Ellinghaus, Eva
Rushbrook, Simon M.
Doncheva, Nadezhda T.
Andreassen, Ole A.
Weersma, Rinse K.
Weismuller, Tobias J.
Eksteen, Bertus
Invernizzi, Pietro
Hirschfield, Gideon M.
Gotthardt, Daniel Nils
Pares, Albert
Ellinghaus, David
Shah, Tejas
Juran, Brian D.
Milkiewicz, Piotr
Rust, Christian
Schramm, Christoph
Muller, Tobias
Srivastava, Brijesh
Dalekos, Georgios
Nothen, Markus M.
Herms, Stefan
Winkelmann, Juliane
Mitrovic, Mitja
Braun, Felix
Ponsioen, Cyriel Y.
Croucher, Peter J. P.
Sterneck, Martina
Teufel, Andreas
Mason, Andrew L.
Saarela, Janna
Leppa, Virpi
Dorfman, Ruslan
Alvaro, Domenico
Floreani, Annarosa
Onengut-Gumuscu, Suna
Rich, Stephen S.
Thompson, Wesley K.
Schork, Andrew J.
Naess, Sigrid
Thomsen, Ingo
Mayr, Gabriele
Konig, Inke R.
Hveem, Kristian
Cleynen, Isabelle
Gutierrez-Achury, Javier
Ricano-Ponce, Isis
van Heel, David
Bjornsson, Einar
Sandford, Richard N.
Durie, Peter R.
Melum, Espen
Vatn, Morten H.
Silverberg, Mark S.
Duerr, Richard H.
Padyukov, Leonid
Brand, Stephan
Sans, Miquel
Annese, Vito
Achkar, Jean-Paul
Boberg, Kirsten Muri
Marschall, Hanns-Ulrich
Chazouilleres, Olivier
Bowlus, Christopher L.
Wijmenga, Cisca
Schrumpf, Erik
Vermeire, Severine
Albrecht, Mario
The UK-PSCSC Consortium,
The International IBD Genetics Consortium,
Rioux, John D.
Alexander, Graeme
Bergquist, Annika
Cho, Judy
Schreiber, Stefan
Manns, Michael P.
Farkkila, Martti
Dale, Anders M.
Chapman, Roger W.
Lazaridis, Konstantinos N.
The International PSC Study Group,
Franke, Andre
Anderson, Carl A.
Karlsen, Tom H. | | Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis
In: Nature Genetics [45], 670-677 |  |
| | | Neumann-Fraune, Maria
Beggel, Bastian
Pfister, Herbert
Kaiser, Rolf
Verheyen, Jens | | High frequency of complex mutational patterns in lamivudine resistant hepatitis B virus isolates
In: Journal of Medical Virology [200], 39-49 |  |
 |  |  | Pironti, Alejandro | | HIV-1 fitness landscape models for indinavir treatment pressure using observed evolution in longitudinal sequence data are predictive for treatment failure
In: Infection, Genetics and Evolution [19], 349–360 |  |
| | | Radivojac, Predrag
Clark, Wyatt T
Oron, Tal Ronnen
Schnoes, Alexandra M
Wittkop, Tobias
Sokolov, Artem
Graim, Kiley
Funk, Christopher
Verspoor, Karin
Ben-Hur, Asa
Pandey, Gaurav
Yunes, Jeffrey M
Talwalkar, Ameet S
Repo, Susanna
Souza, Michael L
Piovesan, Damiano
Casadio, Rita
Wang, Zheng
Cheng, Jianlin
Fang, Hai
Gough, Julian
Koskinen, Patrik
T\"{o}r\"{o}nen, Petri
Nokso-Koivisto, Jussi
Holm, Liisa
Cozzetto, Domenico
Buchan, Daniel W A
Bryson, Kevin
Jones, David T
Limaye, Bhakti
Inamdar, Harshal
Datta, Avik
Manjari, Sunitha K
Joshi, Rajendra
Chitale, Meghana
Kihara, Daisuke
Lisewski, Andreas M
Erdin, Serkan
Venner, Eric
Lichtarge, Olivier
Rentzsch, Robert
Yang, Haixuan
Romero, Alfonso E
Bhat, Prajwal
Paccanaro, Alberto
Hamp, Tobias
Ka\ss ner, Rebecca
Seemayer, Stefan
Vicedo, Esmeralda
Schaefer, Christian
Achten, Dominik
Auer, Florian
Boehm, Ariane
Braun, Tatjana
Hecht, Maximilian
Heron, Mark
H\"{o}nigschmid, Peter
Hopf, Thomas A
Kaufmann, Stefanie
Kiening, Michael
Krompass, Denis
Landerer, Cedric
Mahlich, Yannick
Roos, Manfred
Bj\"{o}rne, Jari
Salakoski, Tapio
Wong, Andrew
Shatkay, Hagit
Gatzmann, Fanny
Sommer, Ingolf
Wass, Mark N
Sternberg, Michael J E
Skunca, Nives
Supek, Fran
Bo\v{s}njak, Matko
Panov, Pan\v{c}e
D\v{z}eroski, Sa\v{s}o
Smuc, Tomislav
Kourmpetis, Yiannis A I
van Dijk, Aalt D J
Braak, Cajo J F Ter
Zhou, Yuanpeng
Gong, Qingtian
Dong, Xinran
Tian, Weidong
Falda, Marco
Fontana, Paolo
Lavezzo, Enrico
{Di Camillo}, Barbara
Toppo, Stefano
Lan, Liang
Djuric, Nemanja
Guo, Yuhong
Vucetic, Slobodan
Bairoch, Amos
Linial, Michal
Babbitt, Patricia C
Brenner, Steven E
Orengo, Christine
Rost, Burkhard
Mooney, Sean D
Friedberg, Iddo | | A large-scale evaluation of computational protein function prediction
In: Nature Methods [10], 221-227 |  |
 |  |  | Röttger, Richard
Kalaghatgi, Prabhav
Sun, Peng
de Castro Soares, Siomar
Azevedo, Vasco
Wittkop, Tobias
Baumbach, Jan | | Density Parameter Estimation for Finding Clusters of Homologous Proteins - Tracing Actinobacterial Pathogenicity Life Styles
In: Bioinformatics [29], 215-222 |  |
| | | Sandoval, Juan
Mendez-Gonzales, Jesus
Nadal, Ernest
Chen, Guoan
Carmona, F. Javier
Sayols, Sergi
Moran, Sebastian
Heyn, Holger
Vizoso, Miguel
Gomez, Antonio
Sanchez-Cespedes, Montse
Assenov, Yassen
Müller, Fabian
Bock, Christoph
Taron, Miquel
Mora, Josefina
Muscarella, Lucia A.
Liloglou, Triantafillos
Davies, Michael
Pollan, Marina
Pajares, Maria J.
Torre, Wenceslao
Montuenga, Luis M.
Brambilla, Elisabeth
Field, John K.
Roz, Luca
Lo Iacono, Marco
Scagliotti, Giorgio V.
Rosell, Rafael
Beer, David G.
Esteller,Manel | | A Prognostic DNA Methylation Signature for Stage I Non-Small-Cell Lung Cancer
In: Journal of Clinical Oncology [31], 4140-4147 |  |
 |  |  | Schelhorn, Sven-Eric
Fischer, M.
Tolosi, Laura
Altmüller, J.
Nürnberg, P.
Pfister, H.
Lengauer, Thomas
Berthold, F. | | Sensitive detection of viral transcripts in human tumor transcriptomes
In: PLOS Computational Biology [9], xx |  |
| | | Schulz, Marcel Holger
Pandit, Kusum V
Lino Cardenas, Christian L
Ambalavanan,Namasivayam
Kaminski, Naftali
Bar-Joseph, Ziv | | Reconstructing dynamic microRNA-regulated interaction networks
In: Proceedings of the National Academy of Sciences of the United States [110], 15686–15691 |  |
 |  |  | Simmer, F.
Brinkmann, A.B.
Assenov, Yassen
Matarese, F.
Kaan, A.
Lengauer, Thomas
Bock, Christoph
Colantuoni, V.
Altucci, L.
Stunnenberg, H.G. | | Comparative genome-wide DNA methylation analysis of colorectal tumor and matched human tissue
In: Epigenetics [7], 1355-1367 |  |
| | | Steijger, T
Abril, JF
Engström,PG
Kokocinski, F
Abril, JF
Akerman, M
Alioto, T
Ambrosini, G
Antonarakis, SE
Behr, J
Bohnert, R
Bucher, P
Cloonan, N
Derrien, T
Djebali, S
Du, J
Dudoit, S
Engström, PG
Gerstein, M
Gingeras, TR
Gonzalez, D
Grimmond, SM
Habegger, L
Iseli, C
Jean, G
Kahles, A
Kokocinski, F
Lagarde, J
Leng, J
Lefebvre, G
Lewis, S
Mortazavi, A
Niermann, P
Rätsch, G
Reymond, A
Ribeca, P
Richard, H
Rougemont, J
Rozowsky, J
Sammeth, M
Sboner, A
Schulz, Marcel Holger
Searle, SM
Solorzano, ND
Solovyev, V
Stanke, M
Steijger, T
Stevenson, BJ
Stockinger, H
Valsesia, A
Weese, D
White, S
Wold, BJ
Wu, J
Wu, TD
Zeller, G
Zerbino, D
Zhang, MQ
Hubbard, TJ
Guigó, R
Harrow, J
Bertone, P | | Assessment of transcript reconstruction methods for RNA-seq
In: Nature Methods [10], 1177-84 |  |
 |  |  | Tolosi, Laura
Theißen, J.
Halachev, Konstantin
Hero, B.
Berthold, F.
Lengauer, Thomas | | A method for finding consensus breakpoints in the cancer genome from copy number data
In: Bioinformatics [29], 1793-1800 |  |
| | | Zanon, Alessandra
Rakovic, Aleksandar
Blankenburg, Hagen
Doncheva, Nadezhda T.
Schwienbacher, Christine
Serafin, Alice
Alexa, Adrian
Weichenberger, Christian X.
Albrecht, Mario
Klein, Christine
Hicks, Andrew A.
Pramstaller, Peter P.
Domingues, Francisco S.
Pichler, Irene | | Profiling of parkin-binding partners using tandem affinity purification
In: PLoS ONE [8], 1-17 |  |
 |  |  | Ziller, Michael J.
Gu, Hongcang
Müller, Fabian
Donaghey, Julie
Tsai, Linus T.-Y.
Kohlbacher, Oliver
De Jager, Philip L.
Rosen, Evan D.
Bennett, David A.
Bernstein, Bradley E.
Gnirke, Andreas
Meissner, Alexander | | Charting a dynamic DNA methylation landscape of the human genome
In: Nature [500], 477–481 |  |
3 |
|
 | Electronic Journal Article |
|  |
 |  |  | Beggel, Bastian
Lengauer, Thomas | | Inferring short-range linkage information from sequencing chromatograms
In: PLoS One, |  |
| | | Hauschild, Anne-Christin
Kopczynski, Dominik
D'Addario, Marianna
Baumbach, Joerg Ingo
Rahmann, Sven
Baumbach, Jan | | Peak Detection Method Evaluation for Ion Mobility Spectrometry by using Machine Learning Approaches
In: Metabolites [3], 277-293 |  |
 |  |  | Schneider, Till
Hauschild, Anne-Christin
Baumbach, Joerg Ingo
Baumbach, Jan | | An Integrative Clinical Database and Diagnostics Platform for Biomarker Identification and Analysis in Ion Mobility Spectra of Human Exhaled Air
In: Journal of Integrative Bioinformatics [10], |  |
1 |
|
 | Thesis - PhD thesis |
|  |
 |  |  | Patil, Kaustubh Raosaheb | | Genome Signature based Sequence Comparison for Taxonomic Assignment and tree inference
Universität des Saarlandes |  |
1 |
|
 | Miscellaneous |
|  |
 |  |  | Hauschild, Anne-Christin
Baumbach, Joerg Ingo
Baumbach, Jan |  | Paving the Way for Automated Clinical Breath Analysis and Biomarker Detection |  |
69 |
 | 2012 |
|  |
3 |
|
|  |
| | | Emig, Dorothea
Blankenburg, Hagen
Ramírez, Fidel
Albrecht, Mario | | Functional characterization of human genes from exon expression and RNA interference results
In: Bioinformatics and Drug Discovery, 33-53 |  |
 |  |  | Feuerbach, Lars
Halachev, Konstantin
Assenov, Yassen
Mueller, Fabian
Bock, Christoph
Lengauer, Thomas | | Analyzing epigenome data in context of genome evolution and human diseases
In: Evolutionary Genomics : Statistical and Computational Methods, Volume 2, 431-467
In: Methods of Molecular Biology [856], 431-467 |  |
| | | Lengauer, Thomas
Albrecht, Mario
Domingues, Francisco S. | | Computational Biology
In: Encyclopedia of Molecular Cell Biology and Molecular Medicine, 1-71 |  |
2 |
|
|  |
| | | Bogojeska, Jasmina
Stöckel, Daniel
Zazzi, Maurizio
Kaiser, Rolf
Incardona, Francesca
Rosen-Zvi, Michal
Lengauer, Thomas | | History-alignment models for bias-aware prediction of virological response to HIV combination therapy
In: Proceedings of the Fifteenth International Conference on Artificial Intelligence and Statistics (AISTATS 2012), 118-126 |  |
 |  |  | Reppas, Andreas
Lawyer, Glenn |  | Low k-shells identify bridge elements critical to disease flow in small-world networks
In: Numerical Analysis and Applied Mathematics (ICNAAM 2012), 1426-1429 |  |
1 |
|
 | Electronic Proceedings Article |
|  |
 |  |  | Röttger, Richard
Kreutzer, Christoph
Duong Vu, Thuy
Wittkop, Tobias
Baumbach, Jan | | Online Transitivity Clustering of Biological Data with Missing Values
In: German Conference on Bioinformatics 2012 (GCB 2012), 57-68 |  |
4 |
|
 | Poster |
|  |
 |  |  | Obermeier, Martin
Camacho, Ricardo
Charpentier, Charlotte
Deschamps, Diane
Eberle, Joseph
Gürtler, Lutz
Ruelle, Jean
Pironti, Alejandro
Brun-Veziet, Francoise
Stürmer, Martin
Kaiser, Rolf | | HIV2EU: supporting standardized HIV-2 drug resistance interpretation in Europe
In: Journal of the International AIDS Society, 135 |  |
| | | Pironti, Alejandro
Lengauer, Thomas
Kaiser, Rolf
Schülter, Eugen
Verheyen, Jens | | Characterization of HIV-1 Gag Subtype C
In: Abstract Book. 9th Workshop on HIV \& Hepatitis Treatment Strategies \& Antiviral Drug Resistance, 40-41 |  |
 |  |  | Schuelter, Eugen
Lübcke, Nadine
Jensen, Björn
Zazzi, Maurizio
Sönnerborg, Anders
Lengauer, Thomas
Incardona, Francesca
Camacho, Richardo
Schmit, J
Clotet, Bonaventura
Kaiser, Rolf
Pironti, Alejandro | | Etravirine in protease inhibitor-free antiretroviral combination therapies
In: Journal of the International AIDS Society, 155-156 |  |
| | | Sierra, Saleta
Dzbowski, Jan Nikolaj
Pironti, Alejandro
Gueney, L
Thielen, Alexander
Reuter, Stefan
Esser, Stefan
Fätkenheuer, Gerd
Lengauer, Thomas
Hider, Dominik
Hoffmann, Daniel
Pfister, Holger
Jensen, Björn
Kaiser, Rolf | | Optimisation of baseline genotypic testing for safe and efficient maraviroc administration
In: Journal of the International AIDS Society, 101-102 |  |
40 |
|
|  |
| | | Adams, David
Altucci, Lucia
Antonarakis, Stylianos E
Ballesteros, Juan
Beck, Stephan
Bird, Adrian
Bock, Christoph
Boehm, Bernhard
Campo, Elias
Caricasole, Andrea
Dahl, Fredrik
Dermitzakis, Emmanouil T
Enver, Tariq
Esteller, Manel
Estivill, Xavier
Ferguson-Smith, Anne
Fitzgibbon, Jude
Flicek, Paul
Giehl, Claudia
Graf, Thomas
Grosveld, Frank
Guigó, Roderic
Gut, Ivo
Helin, Kristian
Jarvius, Jonas
Küppers, Ralf
Lehrach, Hans
Lengauer, Thomas
Lernmark, Åke
Leslie, David
Loeffler, Markus
Macintyre, Elizabeth
Mai, Antonello
Martens, Joost H A
Minucci, Saverio
Ouwehand, Willem H
Pelicci, Pier Giuseppe
Pendeville, Hèléne
Porse, Bo
Rakyan, Vardhman
Reik, Wolf
Schrappe, Martin
Schübeler, Dirk
Seifert, Martin
Siebert, Reiner
Simmons, David
Soranzo, Nicole
Spicuglia, Salvatore
Stratton, Michael
Stunnenberg, Hendrik G
Tanay, Amos
Torrents, David
Valencia, Alfonso
Vellenga, Edo
Vingron, Martin
Walter, Jörn
Willcocks, Spike | | BLUEPRINT to decode the epigenetic signature written in blood
In: Nature Biotechnology [30], 224-226 |  |
 |  |  | Alcaraz, Nicolas
Kucuk, Hande
Weile, Jochen
Wipat, Anil
Baumbach, Jan | | KeyPathwayMiner - Detecting case-specific biological pathways by using expression data
In: Internet Mathematics [7], 299-313 |  |
| | | Baumbach, Jan | | Integrative computational biology
In: Integrative Biology [4], 713-714 |  |
 |  |  | Beggel, Bastian
Neumann-Fraune, Maria
Doering, Matthias
Lawyer, Glenn
Kaiser, Rolf
Verheyen, Jens
Lengauer, Thomas | | Genotyping hepatitis B virus dual infections using population-based sequence data
In: Journal of General Virology [9], 1899-1907 |  |
| | | Bhattacharyya, Malay
Feuerbach, Lars
Bhadra, Tapas
Bandyopadhyay, Sanghamitra | | MicroRNA Transcription Start Site Prediction with Multi-objective Feature Selection
In: Statistical Applications in Genetics and Molecular Biology [11], 6.1-6.25 |  |
 |  |  | Bock, Christoph | | Analysing and interpreting DNA methylation data
In: Nature Reviews Genetics [13], 705-719 |  |
| | | Bock, Christoph
Lengauer, Thomas | | Epigenom-Karten erstellen und nutzen
In: BIOspektrum [18], 138-141 |  |
 |  |  | Bock, Christoph
Lengauer, Thomas | | Managing drug resistance in cancer: lessons from HIV therapy
In: Nature Reviews Cancer [12], 494-501 |  |
| | | Bogojeska, Jasmina
Lengauer, Thomas | | Hierarchical Bayes Model for Predicting Effectiveness of HIV Combination Therapies
In: Statistical Applications in Genetics and Molecular Biology [11], 11.1-11.19 |  |
 |  |  | Bozek, Katarzyna
Eckhardt, Manon
Sierra, Saleta
Kaiser, Rolf
Kräusslich, Hans-Georg
Müller, Barbara
Lengauer, Thomas | | An expanded model of HIV cell entry phenotype based on multi-parameter single-cell data
In: Retrovirology [9], 60.1-60.15 |  |
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Universität des Saarlandes |  |
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Universität des Saarlandes |  |
| | | Zeidler, Michael | | Cloudbasierte Analyse von viralen Sequenzdaten der neuesten Generation
Universität des Saarlandes |  |
8 |
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Universität des Saarlandes |  |
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Universität des Saarlandes |  |
| | | Eldarov, Nasimi | | Modeling influenza evolution in response to immune system pressure
Universität des Saarlandes |  |
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Universität des Saarlandes |  |
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Universität des Saarlandes |  |
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Universität des Saarlandes |  |
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Universität des Saarlandes |  |
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Universität des Saarlandes |  |
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Albrecht, Mario
Eom, Jae-Hong
Weikum, Gerhard | | DIDO: a disease-determinants ontology from web sources
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Visca, Michela
Gallinaro, Valentina
Marino, Nicoletta
Mazzotta, Francesco
De Sanctis, Giuseppe Maria
Fleury, Hervè
Trimoulet, Pascale
Angelico, Mario
Cappiello, Giuseppina
Zhang, Xin Xin
Verheyen, Jens
Ceccherini-Silberstein, Francesca
Perno, Carlo Federico | | Role of hepatitis B virus genetic barrier in drug-resistance and immune-escape development
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Mo, Theresa
Dong, Winnie WY
Zhong, Xiaoyin
Woods, Conan K
Thielen, Alexander
Jensen, Mark A
Knapp, David JHF
Chapman, Douglass
Lewis, Marilyn
James, Ian
Heera, Jayvant
Valdez, Hernan
Harrigan, P Richard | | Deep V3 sequencing for HIV type 1 tropism in treatment-naive patients: a reanalysis of the MERIT trial of maraviroc.
In: Clinical Infectious Diseases [53], 732-742 |  |
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Mo, Theresa
Dong, Winnie W. Y.
Zhong, Xiaoyin
Woods, Conan K.
Jensen, Mark A.
Thielen, Alexander
Chapman, Douglass
Lewis, Marilyn
James, Ian
Heera, Jayvant
Valdez, Hernan
Harrigan, P. Richard | | Deep Sequencing to Infer HIV-1 Co-Receptor Usage: Application to Three Clinical Trials of Maraviroc in Treatment-Experienced Patients
In: The Journal of Infectious Diseases [203], 237-245 |  |
| | | Thielen, Alexander
Lengauer, Thomas
Swenson, Luke C
Dong, Winnie W.Y.
McGovern, Rachel A
Lewis, Marilyn
James, Ian
Heera, Jayvant
Valdez, Hernan
Harrigan, P Richard | | Mutations in gp41 are correlated with coreceptor tropism but do not improve prediction methods substantially
In: Antiviral Therapy [16], 319-328 |  |
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Lengauer, Thomas | | Classification with correlated features: unreliability of feature ranking and solutions
In: Bioinformatics [27], 1986-1994 |  |
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Welsch, Christoph
Ochs, D.
Hofmann, W. P.
Herrmann, E.
Piiper, A.
Hartmann, R. W.
Zeuzem, S.
Sarrazin, C.
Kronenberger, Bernd | | Comparison of Envelope 2 CD81 binding regions in PBMC-derived versus serum-derived hepatitis C virus isolates: higher conservation of CD81 region 2 in PBMC isolates
In: Journal of Viral Hepatitis [18], 181-192 |  |
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Emig, Dorothea
Truss, Anke
Albrecht, Mario
Böcker, Sebastian
Baumbach, Jan | | Comprehensive cluster analysis with Transitivity Clustering
In: Nature Protocols [6], 285-295 |  |
| | | Wittkop, Tobias
Rahmann, Sven
Roettger, Richard
Boecker, Sebastian
Baumbach, Jan | | Extension and robustness of Transitivity Clustering for protein-protein interaction network analysis
In: Internet Mathematics [7], 255-273 |  |
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Bock, Christoph
Müller, Fabian
Sun, Deqiang
Meissner, Alexander
Li, Wei | | RRBSMAP: A Fast, Accurate and User-friendly Alignment Tool for Reduced Representation Bisulfite Sequencing
In: Bioinformatics [28], 430-432 |  |
| | | Yamanishi, Yoshihiro
Pauwels, Edouard
Saigo, Hiroto
Stovent, Veronique | | Extracting Sets of Chemical Substructures and Protein Domains Governing Drug-Target Interactions
In: Journal of Chemical Information and Modeling [51], 1183-1194 |  |
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Fillmore, Christine M.
Lau, Allison N.
Gludish, David W.
Chou, alan
Ho, Joshua W. K.
Zamponi, Raffaella
Gazit, Roi
Bock, Christoph
Jäger, Natalie
Smith, Zachary D.
Kim, Tae-min
Saunders, Arven H.
Wong, Janice
Lee, Joo-Hyeon
Roach, Rebecca R.
Rossi, Derrick J.
Meissner, Alex
Gimelbrant, Alexander A.
Park, Peter J.
Kim, Carla F. | | Lung stem cell self-renewal relies on BMI1-dependent control of expression at imprinted loci
In: Cell Stem Cell [9], 272-280 |  |
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Kaiser, R.
Sönnerborg, A.
Struck, D
Altmann, Andre
Prosperi, M.
Rosen-Zvi, M.
Petroczi, A.
Peres, Y.
Schülter, E.
Boucher, C.A.
Brun-Vezinet, F.
Harrigan, R.
Morris, L.
Obermeier, M.
Perno, C.-F.
Phanuphak, P.
Pillay, D
Shafer, R.W.
Vandamme, A.-M.
Van Laethem, K.
Wensing, A.
Lengauer, Thomas
Incardona, F. | | Prediction of Response to Antiretroviral Therapy by Human Experts and by the EuResist Data-Driven Expert System (the EVE study)
In: HIV Medicine [12], 211-218 |  |
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|  |
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Pou, Christian
Thielen, Alexander
García, Federico
Delgado, Rafael
Dalmau, David
Álvarez-Tejado, Miguel
Ruiz, Lidia
Clotet, Bonaventura
Paredes, Roger | | Added value of deep sequencing relative to population sequencing in heavily pre-treated HIV-1-infected subjects
In: PLoS One [6], e19461,1-e19461,5 |  |
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Kaiser, Rolf
Klein, Rolf
Lengauer, Thomas
Thiele, Bernhard
Thielen, Alexander | | Genotypic tropism testing by massively parallel sequencing: qualitative and quantitative analysis
In: BMC Medical Informatics and Decision Making [11], 30,1-30,8 |  |
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Lakizadeh, Amir
Agha-Golzadeh, Esmaeil
Ebrahimi, Mahdi | | Prediction of Thermostability from Amino Acid Attributes by Combination of Clustering with Attribute Weighting: A New Vista in Engineering Enzymes
In: PLoS One [6], e23146,1-e23146,11 |  |
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Sander, Oliver
Mayr, Gabriele
Albrecht, Mario | | Structure collisions between interacting proteins
In: PLoS ONE [6], e19581,1-e19581,7 |  |
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D'Afonseca, Vivian
Silva, Artur
Ali, Amjad
Pinto, Anne C.
Santos, Anderson R.
Rocha, Aryanne A. M. C.
Lopes, Debora O.
Dorella, Fernanda A.
Pacheco, Luis G. C.
Costa, Marcilia P.
Turk, Meritxell Z.
Seyffert, Nubia
Moraes, Pablo M. R. O.
Soares, Siomar C.
Almeida, Sintia S.
Castro, Thiago L. P.
Abreu, Vinicius A. C.
Trost, Eva
Baumbach, Jan
Tauch, Andreas
Schneider, Maria P. C.
McCulloch, John
Cerdeira, Louise T.
Ramos, Rommel T. J.
Zerlotini, Adhemar
Dominitini, Anderson
Resende, Daniela M.
Coser, Elisangela M.
Oliveira, Luciana M.
Pedrosa, Andre L.
Vieira, Carlos U.
Guimaraes, Claudia T.
Bartholomeu, Daniela C.
Oliveira, Diana M.
Santos, Fabricio R.
Rabelo, Elida Mara
Lobo, Francisco P.
Franco, Gloria R.
Costa, Ana Flavia
Castro, Ieso M.
Dias, Silvia Regina
Ferro, Jesus A.
Ortega, Jose Miguel
Paiva, Luciano V.
Goulart, Luiz R.
Almeida, Juliana Franco
Ferro, Maria Ines
Carneiro, Newton P.
Falcao, Paula R. K.
Grynberg, Priscila
Teixeira, Santuza M. R.
Brommonschenkel, Sergio
Oliveira, Sergio C.
Meyer, Roberto
Moore, Robert J.
Miyoshi, Anderson
Oliveira, Guilherme C.
Azevedo, Vaco | | Evidence for Reductive Genome Evolution and Lateral Acquisition of Virulence Functions in two Corynebacterium pseudotuberculosis strains
In: PLoS One [6], e18551 |  |
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Altmann, André
Bogojeska, Jasmina
Müller, Fabian
Nowozin, Sebastian
Lengauer, Thomas |  | Learning from past treatments and their outcome improves prediction of In Vivo response to anti-HIV therapy
In: Statistical Applications in Genetics and Molecular Biology [10], 1-32 |  |
| | | Schelhorn, Sven-Eric
Mestre, Julián
Zotenko, Elena
Albrecht, Mario | | Inferring physical protein contacts from large-scale purification data of protein complexes
In: Molecular & Cellular Proteomics [10], M110.004929,1-M110.004929,15 |  |
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Kaiser, Rolf
Lübke, Nadine
Thielen, Alexander
Schuelter, Eugen
Heger, Eva
Däumer, Martin
Reuter, Stefan
Esser, Stefan
Fätkenheuer, Gerd
Pfister, Herbert
Oette, Mark
Lengauer, Thomas | | Prediction of HIV-1 coreceptor usage (tropism) by sequence analysis using a genotypic approach
In: Journal of Visualized Experiments [58], e3264,1-e3264,9 |  |
| | | Ziller, Michael J.
Müller, Fabian
Liao, Jing
Zhang, Yingying
Gu, Hongcang
Bock, Christoph
Boyle, Patrick
Epstein, Charles B.
Bernstein, Bradley E.
Lengauer, Thomas
Gnirke, Andreas
Meissner, Alexander | | Genomic distribution and inter-sample variation of non-CpG methylation across human cell types
In: PLoS Genetics [17], e1002389,1-e1002389,15 |  |
3 |
|
|  |
| | | Döring, Matthias | | Web Implementation of the HBV Dual Infection Model
Universität des Saarlandes |  |
 |  |  | Junge, Alexander | | Unsupervised dissection of cancer types based on genomic, epigenomic and transciptomic features
Universität des Saarlandes |  |
| | | Reuter, Kerstin | | Estimating and Using the Uncertainty in the Phenotypic Resistance Assay of the Hepatitis B Virus to Improve IC-50 Prediction from Genotype
Universität des Saarlandes |  |
6 |
|
|  |
| | | Hauschild, Anne-Christin | | Modeling HIV Neutralization
Universität des Saarlandes |  |
 |  |  | Hoinka, Jan-Malte | | Finding the Hairpin in the Haystack: Towards an High Throughput in Silico Pipeline for Aptamer Motif Identification using SELEX Data
Universität des Saarlandes |  |
| | | Ivanova, Violeta | | Comparison of methods for discovering genomic aberrations relevant for cancer
Universität des Saarlandes |  |
 |  |  | Jing, Cui | | A comprehensive analysis of the illumina Infinium assay
Universität des Saarlandes |  |
| | | Kacprowski, Tim | | Disease gene prioritization by combining network information and functional knowledge
Universität des Saarlandes |  |
 |  |  | Weimann, Aaron | | Functional Profiling in Metagenomics
Universität des Saarlandes |  |
5 |
|
 | Thesis - PhD thesis |
|  |
 |  |  | Bogojeska, Jasmina |  | Statistical Learning Methods for Bias-aware HIV Therapy Screening
Universität des Saarlandes |  |
| | | Bozek, Katarzyna |  | Analysis of HIV-host interaction on different scales.
Universität des Saarlandes |  |
 |  |  | Emig, Dorothea | | Novel analysis approaches to context-dependent molecular networks
Universität des Saarlandes |  |
| | | Kunert, Lars | | Maximal Common Subgraph DAGs: Theory and Application to Virtual Screening in Drug Development
Universität des Saarlandes |  |
 |  |  | Thielen, Alexander | | Genotypic Analysis of HIV-1 Coreceptor Usage
Universität des Saarlandes |  |
59 |
 | 2010 |
|  |
2 |
|
|  |
| | | Bock, Christoph
Von Kuster, Greg
Halachev, Konstantin
Taylor, James
Nekrutenko, Anton
Lengauer, Thomas | | Web-based analysis of (epi-) genome data using EpiGRAPH and Galaxy.
In: Genetic Variation : Methods and Protocols, 275-296
In: Methods of Molecular Biology [628], 275-296 |  |
 |  |  | Ramirez, Fidel | | Tutorial Cytoscape
In: Bioinformática: Aplicaciones a la genómica y proteómica, 73-98 |  |
2 |
|
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|  |
 |  |  | Albrecht, Mario
Kerren, Andreas
Klein, Karsten
Kohlbacher, Oliver
Mutzel, Petra
Paul, Wolfgang
Schreiber, Falk
Wybrow, Michael | | On open problems in biological network visualization
In: Graph Drawing : 17th International Symposium, GD 2009, 256-267 |  |
| | | Emig, Dorothea
Kacprowski, Tim
Albrecht, Mario | | Measuring and analyzing tissue specificity of human genes and protein complexes
In: Seventh International Workshop on Computational Systems
Biology, WCSB 2010, 27-30 |  |
1 |
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Rahmann, Sven
Baumbach, Jan | | Efficient Online Transcription Factor Binding Site Adjustment by Integrating Transitive Graph Projection with MoRAine 2.0
In: Special Issue: 6th International Symposium on Integrative Bioinformatics, 117,1-117,11 |  |
4 |
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Pironti, Alejandro
Perner, Juliane
Büch, Joachim
Lengauer, Thomas | | Determination of clinically relevant cutoffs for HIV-1 phenotypic resistance estimates through a combined analysis of clinical trial and cohort data
In: Abstract Book. 8th European Drug Resistance Workshop, 46 |  |
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Lengauer, Thomas | | Ancestral germline methylation reconstruction of young repeats
In: Transcription, chromatin structure and DNA repair in development and differentiation, 81 |  |
| | | Feuerbach, Lars
Lyngsoe, Rune
Lengauer, Thomas
Hein, Jotun | | Comparative Epigenomiocs - Towards Ancestral Germline Methylome Reconstruction
In: Abstracts of papers presented at the 2010 meeting on The Biology of genomes, 87 |  |
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Lengauer, Thomas
Harrigan, P Richard
Swenson, Luke
Dong, Winnie WY
McGovern, Rachel A
Lewis, Marilyn
James, Ian
Heera, Jayvant
Valdez, Hernan | | Mutations within GP41 are correlated with coreceptor tropism but do not substantially improve coreceptor usage prediction
In: Reviews in Antiviral Therapy & Infectious Diseases, 47-47 |  |
28 |
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| | | Altmann, André
Tolosi, Laura
Sander, Oliver
Lengauer, Thomas | | Permutation importance: an unbiased feature importance measure
In: Bioinformatics [26], 1340-1347 |  |
 |  |  | Baumbach, Jan | | On the power and limits of evolutionary conservation - unraveling bacterial gene regulatory networks
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Tomazou, Eleni M.
Brinkman, Arie B.
Müller, Fabian
Simmer, Femke
Gu, Hongcang
Jäger, Natalie
Gnirke, Andreas
Stunnenberg, Hendrik G.
Meissner, Alexander |  | Quantitative comparison of genome-wide DNA methylation mapping technologies
In: Nature Biotechnology [28], 1106-1114 |  |
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Bickel, Steffen
Altmann, André
Lengauer, Thomas |  | Dealing with sparse data in predicting outcomes of HIV combination therapies
In: Bioinformatics [26], 2085-2092 |  |
| | | Bozek, Katarzyna
Rosahl, A. L.
Gaub, S.
Lorenzen, S.
Herzel, H. | | Circadian transcription in liver
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Hurni, Severine
Streckeisen, Philipp
Mayr, Gabriele
Albrecht, Mario
Yahiaoui, Nabila
Keller, Beat | | Intragenic allele pyramiding combines different specificities of wheat Pm3 resistance alleles
In: The Plant Journal [64], 433-445 |  |
| | | Codoñer, Francisco M
Pou, Christian
Thielen, Alexander
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Delgado, Rafael
Dalmau, David
Santos, José Ramon
Buzón, Maria José
Martínez-Picado, Javier Alvarez-Tejado, Miguel
Clotet, Bonaventura
Ruiz, Lidia
Paredes, Roger | | Dynamic escape of pre-existing raltegravir-resistant HIV-1 from raltegravir selection pressure
In: Antiviral Research [88], 281-286 |  |
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Awerkiew, Sabine
Sierra Aragon, Saleto
Kartashev, Vladimir
Poplavskaja, Tatjana
Klein, Rolf
Sichtig, Nadine
Thielen, Bernhard
Lengauer, Thomas
Roomp, Kirsten
Pfister, Herbert
Kaiser, Rolf | | Short Communication: Selection of Thymidine Analogue Resitance Mutational Patterns in Children from a Common HIV Type 1 Subtype G Source
In: AIDS Research and Human Retroviruses [26], 275-278 |  |
| | | Ellinghaus, Eva
Ellinghaus, David
Stuart, Philip E.
Nair, Rajan P.
Debrus, Sophie
Raelson, John V.
Belouchi, Majid
Fournier, Hélène
Reinhard, Claudia
Ding, Jun
Li, Yun
Tejasvi, Trilokraj
Gudjonsson, Johann
Stoll, Stefan W.
Voorhees, John J.
Lambert, Sylviane
Weidinger, Stephan
Eberlein, Bernadette
Kunz, Manfred
Rahman, Proton
Gladman, Dafna D.
Gieger, Christian
Wichmann, H. Erich
Karlsen, Tom H.
Mayr, Gabriele
Albrecht, Mario
Kabelitz, Dieter
Mrowietz, Ulrich
Abecasis, Gonçalo R.
Elder, James T.
Schreiber, Stefan
Weichenthal, Michael
Franke, Andre | | Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2
In: Nature Genetics [42], 991-995 |  |
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Salomonis, Nathan
Baumbach, Jan
Lengauer, Thomas
Conklin, Bruce R.
Albrecht, Mario | | AltAnalyze and DomainGraph: analyzing and visualizing exon expression data
In: Nucleic Acids Research [38], W755-W762 |  |
| | | Franke, Andre
Balschun, Tobias
Sina, Christian
Ellinghaus, David
Häsler, Robert
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Albrecht, Mario
Wittig, Michael
Buchert, Eva
Nikolaus, Susanna
Gieger, Christian
Wichmann, H. Erich
Sventoraityte, Jurgita
Kupcinskas, Limas
Onnie, Clive M.
Gazouli, Maria
Anagnou, Nicholas P.
Strachan, David
McArdle, Wendy L.
Mathew, Christopher G.
Rutgeerts, Paul
Vermeire, Séverine
Vatn, Morten H.
Krawczak, Michael
Rosenstiel, Philip
Karlsen, Tom H.
Schreiber, Stefan | | Genome-wide association study for ulcerative colitis identifies risk loci at 7q22 and 22q13 (IL17REL)
In: Nature Genetics [42], 292-294 |  |
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Bock, Christoph
Mikkelsen, Tarjei S.
Jäger, Natalie
Smith, Zachary D.
Tomazou, Eleni
Gnirke, Andreas
Lander, Eric S.
Meissner, Alexander |  | Genome-scale DNA methylation mapping of clinical samples at single-nucleotide resolution
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Wang, Ting
Coarfa, Cristian
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Hong, Chibo
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Fouse, Shaun D.
Delaney, Allen
Zhao, Yongjun
Olshen, Adam
Ballinger, Tracy
Zhou, Xin
Forsberg, Kevin J.
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Echipare, Lorigail
O'Geen, Heriette
Lister, Ryan
Pelizzola, Mattia
Xi, Yuanxin
Epstein, Charles B.
Bernstein, Bradley E.
Hawkins, R. David
Ren, Bing
Chung, Wen-Yu
Gu, Hongcang
Bock, Christoph
Gnirke, Andreas
Zhang, Michael Q.
Haussler, David
Ecker, Joseph R.
Li, Wei
Farnham, Peggy J.
Waterland, Robert a.
Meissner, Alexander
Marra, Marco A.
Hirst, Martin
Milosavljevic, Aleksandar
Costello, Joseph F. | | Comparison of sequencing-based methods to profile DNA methylation and identification of monoallelic epigenetic modifications
In: Nature Biotechnology [28], 1097-1105 |  |
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Lengauer, Thomas
Zeuzem, Stefan
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Sarrazin, Christoph | | HLA class I allele associations with HCV genetic variants in patients with chronic HCV genotypes 1a or 1b infection
In: Journal of Hepatology [53], 1022-1028 |  |
| | | Lengauer, Thomas
Altmann, André
Thielen, Alexander
Kaiser, Rolf | | Chasing the AIDS Virus
In: Communications of the ACM [53], 66-74 |  |
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Thielen, Alexander
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Woods, Conan K
Chapman, Douglass
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James, Ian
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Harrigan, P Richard | | Population-based V3 genotypic tropism assay: a retrospective analysis using screening samples from the A4001029 and MOTIVATE studies
In: AIDS [24], 2517-2525 |  |
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Hofmann, W.P.
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Herrmann, E. | | Effect of ribavirin on the frequency of RNAse L cleavage sites within the hepatitis C viral genome
In: Journal of Viral Hepatitis [17], 217-221 |  |
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Albrecht, Mario | | Finding scaffold proteins in interactomes
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Shafer, Robert |  | Hepatitis B virus reverse transcriptase sequence variant database for sequence analysis and mutation discovery
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| | | Bozek, Katarzyna
Lengauer, Thomas | | Positive selection of HIV host factors and the evolution of lentivirus genes
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 |  |  | Kamp, Christel
Wolf, Timo
Bravo, Ignacio G
Kraus, Benjamin
Krause, Birgit
Neumann, Britta
Winskowsky, Gudrun
Thielen, Alexander
Werner, Albrecht
Schnierle, Barbara S | | Decreased HIV diversity after allogeneic stem cell transplantation of an HIV-1 infected patient: a case report.
In: Virology Journal [7], 55,1-55,9 |  |
| | | Kuroishi, Ayumu
Bozek, Katarzyna
Shioda, Tatsuo
Nakayama, Emi E. | | A single amino acid substitution of the human immunodeficiency virus type 1 capsid protein affects viral sensitivity to TRIM5 alpha.
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Rosen-Zvi, Michal
Altmann, Andre
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Di Giambenedetto, Simona
Kaiser, Rolf
Schülter, Eugen
Struck, Daniel
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van de Vijver, David A.
Vandamme, Anne-Mieke
Sönnerborg, Anders | | Antiretroviral Therapy Optimisation without Genotype Resistance Testing: A Perspective on Treatment History Based Models
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Antes, Iris
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Hattori, Masahiro
Kashima, Hisashi
Tsuda, Koji | | Reaction graph kernels predict EC numbers of unknown enzymatic reactions in plant secondary metabolism
In: BMC Bioinformatics [11], S31,1-S31,7 |  |
| | | Weisser, Hendrik
Altmann, André
Sierra, Saleta
Incardona, Francesca
Struck, Daniel
Sönnerborg, Anders
Kaiser, Rolf
Zazzi, Maurizio
Tschochner, Monika
Walter, Hauke
Lengauer, Thomas | | Only Slight Impact of Predicted Replicative Capacity for Therapy Response Prediction
In: PLoSOne [5], e9044,1-e9044,10 |  |
 |  |  | Zazzi, Maurizio
Kaiser, Rolf
Sönnerborg, Anders
Struck, Daniel
Altmann, Andre
Prosperi, Mattia C. F.
Rosen-Zvi, Michal
Petroczi, Andrea
Peres, Yardena
Schülter, Eugen
Boucher, Charles
Brun-Vezinet, Francoise
Harigan, Richard
Morris, Lynn
Obermeier, Martin
Perno, Federico
Shafer, Robert
Vandamme, Anne-Mieke
van Laethem, Kristel
Wensing, Annemarie
Lengauer, Thomas
Incardona, Francesca | | Prediction of Response to Antiretroviral Therapy by Human Experts and by the EuResist Data-Driven Expert System (the EVE Study)
In: HIV Medicine [Early View], 1-8 |  |
5 |
|
 | Thesis - Bachelor thesis |
|  |
 |  |  | Dörr, Barbara | | Using copy number variation fpr predicting susceptibility to glioblastoma
Universität des Saarlandes |  |
| | | Gatzmann, Fanny | | GOdot Sequence - function prediction from protein sequence
Universität des Saarlandes |  |
 |  |  | Kacprowski, Tim | | Analysis of protein complexes and tissue-spedific expression
Universität des Saarlandes |  |
| | | König, Eva | | Env-wide analysis of coreceptor determining sites and subtype-specific differences in HIV-1
Universität des Saarlandes |  |
 |  |  | Speicher, Nora K. | | Network analysis of viral host factors
Universität des Saarlandes |  |
5 |
|
 | Thesis - Masters thesis |
|  |
 |  |  | Kuhn Cuellar, Luis Eugenio | | A probabilistic algorithm for matching protein structures - and its application to detecting functionally relevant patterns
Universität des Saarlandes |  |
| | | Loi, Luu Phuc | | Identifying discriminative motifs for molecular function of proteins
Universität des Saarlandes |  |
 |  |  | Lutsik, Pavlo | | Processing of high-throughput DNA methylation data
Universität des Saarlandes |  |
| | | Perner, Juliane | | Finding local similarities in gene expression patterns between partially reprogrammed cells and know cell types using a module network approach
Universität des Saarlandes |  |
 |  |  | Stöckel, Daniel | | History Based HIV Therapy Outcome Prediction
Universität des Saarlandes |  |
4 |
|
 | Thesis - PhD thesis |
|  |
 |  |  | Altmann, André | | Bioinformatical approaches to ranking of anti-HIV combination therapies and planning of treatment schedules
Universität des Saarlandes |  |
| | | Johannsen, Daniel | | Random Combinatorial Structures and Randomized Search Heuristics
Universität des Saarlandes |  |
 |  |  | Schlicker, Andreas |  | Ontology-based Similarity Measures and their Application in Bioinformatics
Universität des Saarlandes |  |
| | | Zhu, Hongbo | | Characterization, classification and alignment of protein-protein interfaces
Universität des Saarlandes |  |
43 |
|  |
2 |
|
 | Part of a Book |
|  |
 |  |  | Adams, Ben
McHardy, Alice
Lundegaard, C.
Lengauer, Thomas | | Viral Bioinformatics
In: Modern Genome Annotation - The BioSapiens Network, 429-452 |  |
| | | Frishman, Dmitrij
Albrecht, Mario
Blankenburg, Hagen
Bork, Peer
Harrington, Eoghan D.
Hermjakob, Henning
Jensen, Lars J.
Juan, David A.
Lengauer, Thomas
Pagel, Philipp
Schachter, Vincent
Valencia, Alfonso | | Protein-protein interactions: analysis and prediction
In: Modern Genome Annotation - The Biosapiens Network, 353-410 |  |
4 |
|
|  |
| | | Feuerbach, Lars
Halachev, Konstantin
Lengauer, Thomas
Bock, Christoph | | An exhaustive methode for CpG island annotation
In: Special Issue: Abstracts of the 3rd MC-GARD Meeting, 146-146 |  |
 |  |  | Harrigan, P Richard
McGovern, Rachel
Dong, Winnie
Thielen, Alexander
Jensen, Mark
Mo, Theresa
Chapman, Douglas
Lewis, Marilyn
James, Ian
Valdez, Hernan | | Screening for HIV tropism using population-based V3 genotypic analysis: a retrospective outcome analysis using stored plasma screening samples from MOTIVATE-1
In: Abstracts presented at the XVIII International HIV Drug Resistance Workshop : Basic Principles & Clinical Implications, A17-A17 |  |
| | | Thielen, Alexander
Altmann, André
Bogojeska, Jasmina
Kaiser, Rolf
Lengauer, Thomas | | Estimating evolutionary pathways to 7CXCR4 usage from cross-sectional data
In: Abstracts presented at the XVIII International HIV Drug Resistance Workshop : Basic Principles & Clinical Implications, A16-A16 |  |
 |  |  | Thielen, Alexander
Sichtig, Nadine
Braun, Patrick
Däumer, Martin
Walter, Hauke
Noah, Christian
Wolf, Eva
Müller, Harm
Stürmer, Martin
Lengauer, Thomas
Kaiser, Rolf
Obermeier, Martin | | Performance of genotypic coreceptor measurement using geno2pheno[coreceptor] in B- and non-B HIV subtypes in a large cohort of therapy-experienced patients in Germany
In: Reviews in Antiviral Therapy, 99-99 |  |
22 |
|
 | Journal Article |
|  |
 |  |  | Alcaro, Stefano
Artese, Anna
Ceccherini-Silberstein, Francesca
Ortuso, Francesca
Perno, Carlo Federico
Sing, Tobias
Svicher, Valentina | | Molecular Dynamics and Free Energy Studies on the Wild-Type and Mutated HIV-1
Protease Complexed with Four Approved Drugs: Mechanism of Binding and
In: Journal of Chemical Information and Modeling [49], 1751-1761 |  |
| | | Altmann, André
Däumer, Martin
Beerenwinkel, Niko
Peres, Yardena
Schülter, Eugen
Büch, Joachim
Rhee, Soo-Yon
Sönnerborg, Anders
Fessel, W. Jeffrey
Shafer, Robert W.
Zazzi, Maurizio
Kaiser, Rolf
Lengauer, Thomas | | Predicting the Response to Combination Antiretroviral Therapy: Retrospective Validation of
geno2pheno-THEO on a Large Clinical Database
In: The Journal of Infectious Diseases [199], 999-1006 |  |
 |  |  | Altmann, André
Sing, Tobias
Vermeiren, Hans
Winters, Bart
Van Craenenbroeck, Elke
Van der Borght, Koen
Rhee, Soo-Yon
Shafer, Robert W.
Schülter, Eugen
Kaiser, Rolf
Peres, Yardena
Sönnerborg, Anders
Fessel, W. Jeffrey
Incardona, Francesca
Zazzi, Maurizio
Bacheler, Lee
Van Vlijmen, Hermann
Lengauer, Thomas | | Advantages of Predicted Phenotypes and Statistical Learning Models in Inferring Virological Response to Antiretroviral Therapy from HIV Genotype
In: Antiviral Therapy [14], 273-283 |  |
| | | Blankenburg, Hagen
Finn, Robert D.
Prlić, Andreas
Jenkinson, Andrew M.
Ramírez, Fidel
Emig, Dorothea
Schelhorn, Sven-Eric
Büch, Joachim
Lengauer, Thomas
Albrecht, Mario | | DASMI: exchanging, annotating and assessing molecular interaction data
In: Bioinformatics [25], 1321-1328 |  |
 |  |  | Bock, Christoph |  | Epigenetic biomarker development
In: Epigenomics [1], 99-110 |  |
| | | Bock, Christoph
Halachev, Konstantin
Büch, Joachim
Lengauer, Thomas |  | EpiGRAPH: user-friendly software for statistical analysis and prediction of (epi)genomic data
In: Genome Biology [10], R14.1-R14.14 |  |
 |  |  | Hartmann, Christoph
Antes, Iris
Lengauer, Thomas | | Docking and scoring with alternative side-chain conformations
In: Proteins: Structure, Function, and Bioinformatics [74], 712-726 |  |
| | | Kono, Ken
Bozek, Kasia
Domingues, Francisco S.
Shioda, Tatsuo
Nakayama, Emi E. | | Impact of a single amino acid in the variable region 2 of the Old World monkey TRIM5alpha SPRY (B30.2) domain on anti-human immunodeficiency virus type 2 activity
In: Virology [388], 160-168 |  |
 |  |  | Lawyer, Glenn
Ferkingstad, Egil
Nesvåg, Rangan
Varnäs, Katarina
Agartz, Ingrid | | Local and covariate-modulated false discovery rates applied in neuroimaging
In: NeuroImage [47], 213-219 |  |
| | | Lawyer, Glenn
Nesvåg, Ragnar
Varnäs, Katarina
Okugawa, Gaku
Agartz, Ingrid | | Grey and white matter proportional relationships in the cerebellar vermis altered in schizophrenia
In: Cerebellum [8], 52-60 |  |
 |  |  | Lengauer, Thomas
Altmann, André
Thielen, Alexander | | Bioinformatische Unterstützung der Auswahl von HIV Therapien
In: Informatik Spektrum [32], 320-331 |  |
| | | Lengauer, Thomas
Kaiser, Rolf | | Computerjagd auf das AIDSVIRUS
In: Spektrum der Wissenschaft [08], 62-67 |  |
 |  |  | Lengauer, Thomas
Sierra, S.
Kaiser, Rolf | | Resistenzbestimmung
In: MMW Fortschritte in der Medizin [151], 74-75 |  |
| | | Mihm, Ulrike
Ackermann, Oliver
Welsch, Christoph
Herrmann, Eva
Hofmann, Wolf Peter
Grigorian, Natalia
Welker, Martin Walter
Lengauer, Thomas
Zeuzem, Stefan
Sarrazin, Christoph | | Clinical relevance of the 2'-5'-oligoadenylate synthetase/RNase L system for treatment response in chronic hepatitis C
In: Journal of Hepatology [50], 49-58 |  |
 |  |  | Moser, Dirk
Ekawardhani, Savira
Kumsta, Robert
Palmason, Haukur
Bock, Christoph
Athanassiadou, Zoi
Lesch, Klaus-Peter
Meyer, Jobst |  | Functional Analysis of a Potassium-Chloride Co-Transporter 3 (SLC12A6) Promoter Polymorphism Leading to an Additional DNA Methylation Site
In: Neuropsychopharmacology [34], 458-467 |  |
| | | Prosperi, Mattia C. F.
Altmann, André
Rosen-Zvi, Michal
Aharoni, Ehud
Gabor, Borgulya
Fulop, Bazso
Sonnerborg, Anders
Schulter, Eugen
Struck, Daniel
Ulivi, Giovanni
Vandamme, Anne-Mieke
Vercauteren, Jurgen
Zazzi, Maurizio | | Investigation of expert rule bases, logistic regression, and non-linear machine learning techniques for predicting response to antiretroviral treatment
In: Antiviral Therapy [14], 433-442 |  |
 |  |  | Roomp, Kirsten
Rand, Jacquie | | Intensive blood glucose control is safe and effective in diabetic cats using home monitoring and treatment with glargine
In: Journal of feline medicine and surgery [11], 668-682 |  |
| | | Schüffler, Peter
Mikeska, Thomas
Waha, Andreas
Lengauer, Thomas
Bock, Christoph |  | MethMarker: User-friendly design and optimization of gene-specific DNA methylation assays
In: Genome Biology [10], R105:1-R105:10 |  |
 |  |  | Sichtig, Nadine
Sierra, Saleta
Kaiser, Rolf
Däumer, Martin
Reuter, Stefan
Schülter, Eugen
Altmann, André
Fätkenheuer, Gerd
Dittmer, Ulf
Pfister, Herbert
Esser, Stefan | | Evolution of raltegravir resistance during therapy
In: Journal of antimicrobial chemotherapy [64], 25-32 |  |
| | | Sos, Martin L.
Michel, Kathrin
Zander, Thomas
Weiss, Jonathan
Frommolt, Peter
Pfeifer, Martin
Li, Danan
Ullrich, Roland
Koker, Mirjam
Fischer, Florian
Shimamura, Takeshi
Rauh, Daniel
Mermel, Craig
Fischer, Stefanie
Stückrath, Isabel
Heynck, Stefanie
Beroukhim, Rameen
Lin, William
Winckler, Wendy
Shah, Kinjal
LaFramboise, Thomas
Moriarty, Whei F.
Hanna, megan
Tolosi, Laura
Rahnenführer, Jörg
Verhaak, Roel
Chiang, Derek
Getz, Gad
Hellmich, Martin
Wolf, Jürgen
Girard, Luc
Peyton, Michael
Weir, Barbara A.
Chen, Tzu-Hsiu
Greulich, Heidi
Barretina, Jordi
Shapiro, Geoffrey I.
Garraway, Levi A.
Gazdar, Adi F.
Minna, John D.
Meyerson, Matthew
Wong, Kwok-Kin
Thomas, Roman K. | | Predicting drug susceptibility of non-small cell lung cancers based on genetic lesions
In: Journal of Clinical Investigation [119], 1727-1740 |  |
 |  |  | Susser, Simone
Welsch, Christoph
Wang, Yalan
Zettler, Markus
Domingues, Francisco S.
Karey, Ursula
Hughes, Eric
Ralston, Robert
Tong, Xiao
Herrmann, Eva
Zeuzem, Stefan
Sarrazin, Christoph | | Characterization of resistance to the protease inhibitor boceprevir in hepatitis C virus-infected patients.
In: Hepatology [50], 1709-1718 |  |
| | | Trignetti, Maria
Sing, Tobias
Svicher, Valentina
Santoro, Maria Mercedes
Forbici, Federica
D'Arrigo, Roberta
Bellocchi, Maria Concetta
Santoro, Mario
Marconi, Patrizia
Zaccarelli, Mauro
Trotta, Maria Paola
Bellagamba, Rita
Narciso, Pasquale
Antinori, Andrea
Lengauer, Thomas
Perno, Carlo Federico
Ceccherini-Silberstein, Francesca | | Dynamics of NRTI resistance mutations during therapy interruption
In: AIDS Research and Human Retroviruses [25], 57-64 |  |
5 |
|
  | Electronic Journal Article |
|  |
| | | Blankenburg, Hagen
Ramírez, Fidel
Büch, Joachim
Albrecht, Mario | | DASMIweb: online integration, analysis and assessment of distributed protein interaction data
In: Nucleic Acids Research [37], W122-W128 |  |
 |  |  | Bozek, Kasia
Relógio, Angela
Kielbasa, Szymon M.
Heine, Markus
Dame, Christof
Kramer, Achim
Herzel, Hanspeter | | Regulation of clock-controlled genes in mammals.
In: PLoS One [4], e4882:1-e4882:12 |  |
| | | Bozek, Kasia
Thielen, Alexander
Sierra, Saleta
Kaiser, Rolf
Lengauer, Thomas | | V3 loop sequence space analysis suggests different evolutionary patterns of CCR5- and CXCR4-tropic HIV.
In: PLoS One [4], e7387:1-e.7387:14 |  |
 |  |  | McHardy, Alice C.
Adams, Ben | | The role of genomics in tracking the evolution of influenza A virus
In: PLoS Pathog [5], e1000566 |  |
| | | Zhang, Yingying
Rohde, Christian
Tierling, Sascha
Jurkowski, Tomasz P.
Bock, Christoph
Santacruz, Diana
Ragozin, Sergey
Reinhardt, Richard
Groth, Marco
Walter, Jörn
Jeltsch, Albert |  | DNA methylation analysis of chromosome 21 gene promoters at single base pair and single allele resolution
In: PLoS Genetics [5], e1000438:1-e1000438:15 |  |
3 |
|
|  |
| | | Ebert, Peter | | Computational Analysis of genomic HPV data
Universität des Saarlandes |  |
 |  |  | Mangels, Miriam | | In Silico Models for the Prediction of Metabolism by Cytochrome P450 Enzymes
Universität des Saarlandes |  |
| | | Weimann, Aaron | | Using multidimensional Scaling for visualizing similarities of proteins
Universität des Saarlandes |  |
5 |
|
|  |
| | | Diehl, Sarah | | Analysis and reconstruction of protein complex topology
Universität des Saarlandes |  |
 |  |  | Doncheva, Nadezhda, T. | | Analysis and visualization of residue interaction networks
Universität des Saarlandes |  |
| | | Gwinner, Frederik | | Assessing the Conservation of Protein Function on Evolutionary Defined Patches
Universität des Saarlandes |  |
 |  |  | Müller, Fabian | | Assessing Antibody Neutralization of HIV-1 as an Initial Step in the Search for gp160-based Immunogens
Universität des Saarlandes |  |
| | | Pironti, Alejandro | | Probabilistic disease gene prioritization
Universität des Saarlandes |  |
2 |
|
  | Thesis - Habilitation thesis |
|  |
| | | Antes, Iris | | Computational Methods for the Investigation of Protein-Ligand Interactions
Universität des Saarlandes |  |
 |  |  | Sommer, Ingolf |  | From Protein Structure to Function
Universität des Saarlandes |  |
54 |
 | 2008 |
|  |
2 |
|
|  |
| | | Sierra, Saleta
Kaiser, Rolf
Thielen, Alexander
Sander, Oliver
Lengauer, Thomas | | Genotypic Analysis of HIV Co-Receptor Usage
In: Entry Inhibitoren - Neue Formen der HIV-Therapie, 31-39 |  |
 |  |  | Watson, James D.
Thornton, Janet M.
Tress, Michael L.
Lopez, Gonzalo
Valencia, Alfonso
Redfern, Oliver
Orengo, Christine A.
Sommer, Ingolf
Domingues, Francisco S. | | Structure to function
In: Modern Genome Annotation, 239-262 |  |
5 |
|
 | Proceedings Article |
|  |
 |  |  | Bickel, Steffen
Bogojeska, Jasmina
Lengauer, Thomas
Sheffer, Tobias |  | Multi-Task Learning for HIV Therapy Screening
In: Proceedings, Twenty-Fifth International Conference on Machine Learning, 56-63 |  |
| | | Emig, Dorothea
Klein, Karsten
Kunert, Anne
Mutzel, Petra
Albrecht, Mario | | Visualizing domain interaction networks and the impact of alternative splicing events
In: Proceedings of the 5th International Conference on BioMedical Visualization (MediVis): Information Visualization in Medical and Biomedical Informatics, 36-43 |  |
 |  |  | Rosen-Zvi, Michal
Altmann, Andre
Prosperi, Mattia
Aharoni, Ehud
Neuvirth, Hani
Sönnerborg, Anders
Schülter, Eugen
Struck, Daniel
Peres, Yardena
Incardona, Francesca
Kaiser, Rolf
Zazzi, Maurizio
Lengauer, Thomas | | Selecting anti-HIV therapies based on a variety of genomic and clinical factors
In: Proceedings of the 16th Annual International Conference on Intelligent Systems for Molecular Biology (ISMB 2008), i399-406 |  |
| | | Saigo, Hiroto
Tsuda, Koji | | Iterative Subgraph Mining for Principal Component Analysis.
In: Proceedings of the IEEE International Conference on Data Mining (ICDM2008), DM934 |  |
 |  |  | Sander, Oliver
Domingues, Francisco S.
Zhu, Hongbo
Lengauer, Thomas
Sommer, Ingolf | | Structural descriptors of protein-protein binding sites
In: Proceedings of 6th Asia-Pacific Bioinformatics Conference, 79-88 |  |
1 |
|
 | Electronic Proceedings Article |
|  |
 |  |  | Feuerbach, Lars
Christopher, Bock
Halachev, Konstantin
Büch, Joachim
Lengauer, Thomas | | Towards Comparative Epigenomics: A Software Toolkit For Cross-Species Epigenome Data Analysis
In: Abstracts of the 2nd MC-GARD Meeting, 230 |  |
10 |
|
 | Poster |
|  |
 |  |  | Altmann, Andre
Rosen-Zvi, Michal
Prosperi, Mattia
Aharoni, Ehud
Neuvirth, Hani
Schülter, Eugen
Büch, Joachim
Peres, Yardena
Incardona, Incardona
Sönnerborg, Anders
Kaiser, Rolf
Zazzi, Maurizio
Lengauer, Thomas | | The EuResist approach for predicting response to anti HIV-1 therapy
In: Reviews in Antiviral Therapy, 107 |  |
| | | Däumer, Martin
Kaiser, Rolf
Klein, Rolf
Lengauer, Thomas
Thiele, Bernhard
Thielen, Alexander | | Inferring viral tropism from genotype with massively parallel sequencing; qualitative and quantitative analysis
In: Antiviral Therapy, A101 |  |
 |  |  | Moores, Andrew
Thielen, Alexander
Dong, Winnie
Low, Andrew J.
Woods, Conan
Jensen, Mark
Wynhoven, Brian
Chan, Dennison
Glascock, Christopher
Harrigan, P Richard | | Improved detection of X4 virus by V3 genotyping: application to plasma RNA and proviral DNA
In: Antiviral Therapy, A99 |  |
| | | Obermeier, Martin
Berg, Thomas
Sichtig, Nadine
Braun, Patrick
Däumer, Martin
Walter, Hauke
Noah, Christian
Wolf, Eva
Müller, Harm
Stürmer, Martin
Thielen, Alexander
Kaiser, Rolf | | Determination of HIV-1 co-receptor usage in German patients – comparison of genotypic methods with the TROFILE® phenotypic assay
In: Abstracts of the Ninth International Congress on Drug Therapy in HIV Infection, 123 |  |
 |  |  | Obermeier, Martin
Sichtig, Nadine
Braun, Patrick
Däumer, Martin
Walter, Hauke
Noah, Christian
Wolf, Eva
Müller, Harm
Stürmer, Martin
Kaiser, Rolf
Thielen, Alexander | | Determination of HIV-1 coreceptor usage in German patients - comparison of genotypic methods with the TROFILE phenotypic assay
In: Antiviral Therapy, A112 |  |
| | | Rosen-Zvi, Michal
Schülter, Eugen
Altmann, Andre
Sierra-Aragon, Saleta
Zazzi, Maurizio
Sönnerborg, Anders
Oette, Mark
Lengauer, Thomas
Kaiser, Rolf | | Sustaining lamivudine/emtricitabine, abacavir, zidovudine or atazanavir from a previous treatment shows a clinical benefit
In: Antiviral Therapy, A86 |  |
 |  |  | Sander, Oliver
Altmann, Andre
Lengauer, Thomas | | Computational analysis of covariation and interactions between HIV-1 reverse transcriptase and Integrase
In: Reviews in Antiviral Therapy, 113-114 |  |
| | | Thielen, Alexander
Harrigan, P Richard
Low, Andrew J.
Moores, A
Altmann, Andre
Bozek, Kasia
Heger, Eva
Sichtig, Nadine
Kaiser, Rolf
Lengauer, Thomas | | Improved genotypic prediction of HIV-1 coreceptor usage by incorporating V2 loop sequence variation
In: Antiviral Therapy, A100 |  |
 |  |  | Thielen, Alexander
Kaiser, Rolf
Lengauer, Thomas | | Improving HIV-1 coreceptor usage prediction from genotype with regions outside of V3
In: Reviews in Antiviral Therapy, 81-82 |  |
| | | Verheyen, Jens
Altmann, Andre
Knops, Elena
Schülter, Eugen
Sichtig, Nadine
Reuter, Stefan
Fätkenheuer, Gerd
Pfister, Herbert
Kaiser, Rolf | | Relevance of HIV gag cleavage site mutations in failures of protease inhibitor therapies
In: Antiviral Therapy, A53 |  |
23 |
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|  |
| | | Altmann, Andre
Rosen-Zvi, Michal
Prosperi, Mattia
Aharoni, Ehud
Neuvirth, Hani
Sönnerborg, Anders
Schülter, Eugen
Büch, Joachim
Struck, Daniel
Peres, Yardena
Incardona, Francesca
Kaiser, Rolf
Zazzi, Maurizio
Lengauer, Thomas | | Comparison of Classifier Fusion Methods for Predicting Response to Anti HIV-1 Therapy
In: PLoS ONE [3], e3470 |  |
 |  |  | Assenov, Yassen
Ramírez, Fidel
Schelhorn, Sven-Eric
Lengauer, Thomas
Albrecht, Mario | | Computing topological parameters of biological networks
In: Bioinformatics [24], 282-284 |  |
| | | Bock, Christoph | | IVF: stars may have to consider the risk of stolen parenthood
In: Nature [454], 938 |  |
 |  |  | Bock, Christoph
Lengauer, Thomas |  | Computational epigenetics
In: Bioinformatics [24], 1-10 |  |
| | | Bock, Christoph
Walter, Jörn
Paulsen, Martina
Lengauer, Thomas |  | Inter-individual variation of DNA methylation and its implications for large-scale epigenome mapping
In: Nucleic Acids Research [36], e55 |  |
 |  |  | Bogojeska, Jasmina
Alexa, Adrian
Altmann, André
Lengauer, Thomas
Rahnenführer, Jörg |  | Rtreemix: an R package for estimating evolutionary pathways and genetic progression scores
In: Bioinformatics [24], 2391-2392 |  |
| | | Bogojeska, Jasmina
Lengauer, Thomas
Rahnenführer, Jörg | | Stability analysis of mixtures of mutagenetic trees
In: BMC Bioinformatics [9], 165-181 |  |
 |  |  | Emig, Dorothea
Cline, Melissa S.
Klein, Karsten
Kunert, Anne
Mutzel, Petra
Lengauer, Thomas
Albrecht, Mario | | Integrative visual analysis of the effects of alternative splicing on protein domain interaction networks
In: Journal of Integrative Bioinformatics [5], 101-115 |  |
| | | Emig, Dorothea
Cline, Melissa S.
Lengauer, Thomas
Albrecht, Mario | | Integrating expression data with domain interaction networks
In: Bioinformatics [24], 2546-2548 |  |
 |  |  | Franke, Andre
Balschun, Tobias
Karlsen, Tom H.
Sventoraityte, Jurgita
Nikolaus, Susanna
Mayr, Gabriele
Domingues, Francisco S.
Albrecht, Mario
Nothnagel, Michael
Ellinghaus, David
Sina, Christian
Onnie, Clive M.
Weersma, Rinse K.
Stokkers, Pieter C. F.
Wijmenga, Cisca
Gazouli, Maria
Strachan, David
McArdle, Wendy L.
Vermeire, Séverine
Rutgeers, Paul
Rosenstiel, Philip
Krawczak, Michael
Vatn, Morten H.
IBSEN study group, the
Mathew, Christopher G.
Schreiber, Stefan | | Sequence variants in IL10, ARPC2, and multiple other loci contribute to ulcerative colitis
In: Nature Genetics [40], 1319-1323 |  |
| | | Hornstein, Max
Hoffmann, Michele J.
Alexa, Adrian
Yamanaka, Masanori
Müller, Mirko
Jung, Volker
Rahnenführer, Jörg
Schulz, Wolfgang A. | | Protein phosphatase and TRAIL receptor genes as new candidate tumor genes on chromosome 8p in prostate cancer
In: Cancer Genomics & Proteomics [5], 123-136 |  |
 |  |  | Jenkinson, Andrew M.
Albrecht, Mario
Birney, Ewan
Blankenburg, Hagen
Down, Thomas
Finn, Robert D.
Hermjakob, Henning
Hubbard, Tim J. P.
Jimenez, Rafael C.
Jones, Philip
Kähäri, Andreas
Kulesha, Eugene
Macías, José R.
Reeves, Gabrielle A.
Prlić, Andreas | | Integrating biological data - the Distributed Annotation System
In: BMC Bioinformatics [9], S3.1-7 |  |
| | | Kircher, Martin
Bock, Christoph
Paulsen, Martina |  | Structural conservation versus functional divergence of maternally expressed microRNAs in the Dlk1/Gtl2 imprinting region
In: BMC Genomics [9], 346 |  |
 |  |  | Lisurek, Michael
Simgen, Birgit
Antes, Iris
Bernhardt, Rita | | Theoretical and Experimental Evaluation of a CYP106A2 Low Homology Model and Production of Mutants with Changed Activity and Selectivity of Hydroxylation
In: ChemBioChem [9], 1439-1449 |  |
| | | Lucas, Simon
Heim, Ralph
Negri, Matthias
Antes, Iris
Ries, Christina
Schewe, Katarzyna E.
Bisi, Alessandra
Gobbi, Silvia
Hartmann, Rolf W. | | Novel Aldosterone Synthase Inhibitors with Extended Carbocyclic Skeleton by a Combined Ligand-Based and Structure-Based Drug Design Approach
In: Journal of Medical Chemistry [51], 6138-6149 |  |
 |  |  | Schelhorn, Sven-Eric
Lengauer, Thomas
Albrecht, Mario | | An integrative approach for predicting interactions of protein regions
In: Bioinformatics [24], i35-i41 |  |
| | | Schlicker, Andreas
Albrecht, Mario |  | FunSimMat: a comprehensive functional similarity database
In: Nucleic Acids Research [36], D434-D439 |  |
 |  |  | Van Ooijen, Gerben
Mayr, Gabriele
Albrecht, Mario
Cornelissen, Ben J. C.
Takken, Frank L. W. | | Transcomplementation, but not physical association of the CC-NB-ARC and LRR domains of tomato R protein Mi-1.2 is altered by mutations in the ARC2 subdomain
In: Molecular Plant [1], 401-410 |  |
| | | Van Ooijen, Gerben
Mayr, Gabriele
Kasiem, Mobien M. A.
Albrecht, Mario
Cornelissen, Ben J. C.
Takken, Frank L. W. | | Structure-function analysis of the NB-ARC domain of plant disease resistance proteins
In: Journal of Experimental Botany [59], 1383-1397 |  |
 |  |  | Weinhold, Nils
Sander, Oliver
Domingues, Francisco S.
Lengauer, Thomas
Sommer, Ingolf |  | Local function conservation in sequence and structure space
In: PLoS Computational Biology [4], e1000105 |  |
| | | Welsch, Christoph
Domingues, Francisco S.
Susser, Simone
Antes, Iris
Hartmann, Christoph
Mayr, Gabriele
Schlicker, Andreas
Sarrazin, Christoph
Albrecht, Mario
Zeuzem, Stefan
Lengauer, Thomas |  | Molecular basis of telaprevir resistance due to V36 and T54 mutations in the NS3-4A protease of HCV
In: Genome Biology [9], R16 |  |
 |  |  | Zhu, Hongbo
Sommer, Ingolf
Lengauer, Thomas
Domingues, Francisco S. |  | Alignment of Non-Covalent Interactions at Protein-Protein Interfaces
In: PLoS ONE [3], e1926 |  |
| | | Zotenko, Elena
Mestre, Julian
O'Leary, Dianne
Przytycka, Teresa | | Why Do Hubs in the Yeast Protein Interaction Network Tend To Be Essential: Reexamining the Connection between the Network Topology and Essentiality
In: PLoS Computational Biology [4], e1000140 |  |
3 |
|
|  |
| | | Müller, Fabian | | Inferring virological response to antiretroviral combination therapy based on past treatment lines
Universität des Saarlandes |  |
 |  |  | Perner, Juliane |  | Semi-Supervised Learning for Predicting Anti-HIV Drug Resistance
Universität des Saarlandes |  |
| | | Stöckel, Daniel | | Protein Surface Remeshing and Characterisation Using Morse-Smale Complexes
Universität des Saarlandes |  |
3 |
|
|  |
| | | Djoumbou, Yannick | | Molecular Dynamics based prediction of HIV-1 drug resistance
Universität des Saarlandes |  |
 |  |  | Fischer, Sandra | | Structure-based prediction of HIV-1 drug resistance
Universität des Saarlandes |  |
| | | Schüffler, Peter | | MethMarker – A toolkit for design, optimization and validation of DNA methylation biomarkers for cancer diagnosis and therapy optimization
Universität des Saarlandes |  |
7 |
|
|  |
| | | Bock, Christoph | | Computational Epigenetics - Bioinformatic methods for epigenome prediction, DNA methylation mapping and cancer epigenetics
Universität des Saarlandes |  |
 |  |  | Hartmann, Christoph | | Modeling of Flexible Side Chains for Protein-Ligand Docking
Universität des Saarlandes |  |
| | | Maydt, Jochen | | Analysis of recombination in Molecular Sequence Data
Universität des Saarlandes |  |
 |  |  | Sander, Oliver | | Structural Descriptors for the Analysis of Protein Structure, Function, and Evolution
Universität des Saarlandes |  |
| | | Sing, Tobias | | Model-Based Anti HIV Therapy
Universität des Saarlandes |  |
 |  |  | Steffen, Andreas | | Computational Approaches in Supramolecular Chemistry with a special Focus on Virtual Screening
Universität des Saarlandes |  |
| | | Talwar, Priti | | Development of Computational Methods for Metabolic Network Analysis based on Metabolomics Data
Universität des Saarlandes |  |
68 |
|  |
3 |
|
 | Book |
|  |
 |  |  | Lengauer (ed.) | | Bioinformatics - From Genomes to Therapies 1. The Building Blocks: Molecular Sequences and Structures |  |
| | | Lengauer (ed.) | | Bioinformatics - From Genomes to Therapies 2. Getting at the Inner Workings: Molecular Interactions |  |
 |  |  | Lengauer (ed.) | | Bioinformatics - From Genomes to Therapies 3. The Holy Grail: Molecular Function |  |
10 |
|
 | Part of a Book |
|  |
 |  |  | Bock, Christoph
Lengauer, Thomas |  | Computational Epigenetics: Bioinformatik für neue Wege in der Krebsforschung
In: Jahrbuch 2007, 271-277 |  |
| | | Domingues, Francisco S.
Lengauer, Thomas | | Inferring Protein Function from Protein Structure
In: Bioinformatics - From Genomes to Therapies 3. The Holy Grail: Molecular Function, 1211-1252 |  |
 |  |  | Kämper, Andreas
Rognan, Didier
Lengauer, Thomas | | Lead Identification by Virtual Screening
In: Bioinformatics - From Genomes to Therapies 2. Getting at the Inner Workings: Molecular Interactions, 651-704 |  |
| | | Lengauer, Thomas | | Bioinformatik
In: Technologiefüher - Grundlagen, Anwendungen, Trends, 4 |  |
 |  |  | Lengauer, Thomas | | Future Trends
In: Bioinformatics - From Genomes to Therapies 3. The Holy Grail: Molecular Function, 1651-1687 |  |
| | | Lengauer, Thomas | | Introduction
In: Bioinformatics - From Genomes to Therapies 1. The Building Blocks: Molecular Sequences and Structures, 1-24 |  |
 |  |  | Lengauer, Thomas | | Strategiekonzept "Molekulare Bioinformatik"
In: Informatikforschung in Deutschland, 9 |  |
| | | Rahnenführer, Jörg
Lengauer, Thomas | | Analysis of Expression Data: Classification of genes
In: Bioinformatics - From Genomes to Therapies 2. Getting at the Inner Workings: Molecular Interactions, 993-1021 |  |
 |  |  | Roomp, Kirsten | | Evolution of Drug Resistance in HIV
In: Bioinformatics - From Genomes to Therapies 3. The Holy Grail: Molecular Function, 1457-1496 |  |
| | | Sommer, Ingolf | | Protein Fold Recognition Based on Distant Homologs
In: Bioinformatics - From Genomes to Therapies 1. The Building Blocks: Molecular Sequences and Structures, 351-388 |  |
1 |
|
|  |
| | | Lengauer, Rost, Schuster (ed.) | | Proceedings ISMB2007 |  |
1 |
|
|  |
| | | Sing, Tobias
Beerenwinkel, Niko |  | Mutagenetic tree Fisher kernel improves prediction of HIV drug resistance from viral genotype
In: Advances in Neural Information Processing Systems 19, 1-9 |  |
3 |
|
|  |
| | | Altmann, Andre
Däumer, Martin
Sing, Tobias
Beerenwinkel, Niko
Walter, Hauke
Kaiser, Rolf
Lengauer, Thomas | | Validation of geno2pheno and THEO on a large independent clinical dataset
In: Proceedings of the 5th European HIV Drug Resistance Workshop, - |  |
 |  |  | Altmann, Andre
Sing, Tobias
Vermeiren, Hans
Winters, Bart
Van Craenenbroeck, Elke
Van der Borght, Koen
Rhee, Soo-Yon
Shafer, Robert W
Schülter, Eugen
Kaiser, Rolf
Peres, Yardena
Sonnerborg, Anders
Fessel, W Jeffrey
Incardona, Francesca
Zazzi, Maurizio
Bacheler, Lee
Van Vlijmen, Hermann
Lengauer, Thomas | | Inferring virological response from genotype: with or without predicted phenotypes?
In: Proceedings of the 16th International HIV Drug Resistance Workshop, S169 |  |
| | | Zazzi, Maurizio
Aharoni, Ehud
Altmann, Andre
Baszó, Fulop
Bidgood, Penny
Borgulya, Gabór
Denholm-Prince, J
Fielder, M
Kaiser, Rolf
Kent, Carmel
Lengauer, Thomas
Nepusz, T
Neuvirth, Hanni
Peres, Yardena
Petroczi, Andrea
Prosperi, Mattia
Romano, L
Rosen-Zvi, Michal
Schülter, Eugen
Sing, Tobias
Sonnerborg, Andras
Thompson, R
Ulivi, G
Zalány, L
Incardona, Francesca | | EuResist: exploration of multiple modeling techniques for prediction of response to treatment
In: Proceedings of the 5th European HIV Drug Resistance Workshop, - |  |
35 |
|
|  |
| | | Ahlenstiel, G.
Roomp, Kirsten
Däumer, Martin
Nattermann, T.
Vogel, M.
Rockstroh, J.K.
Beerenwinkel, Niko
Kaiser, R.
Nischalke, H.-D.
Sauerbruch, T.
Lengauer, Thomas
Spengler, U. |  | Selective pressures of HLA genotypes and antiviral therapy on human immunodeficiency virus type 1 sequence mutation at a population level
In: Clinical and Vaccine Immunology [14], 1266-1273 |  |
 |  |  | Altmann, Andre
Beerenwinkel, Niko
Sing, Tobias
Savenkov, Igor
Däumer, Martin
Kaiser, Rolf
Rhee, Soo-Yon
Fessel, W Jeffrey
Shafer, Robert W
Lengauer, Thomas | | Improved prediction of response to antiretroviral combination therapy using the genetic barrier to drug resistance
In: Antiviral Therapy [12], 169-178 |  |
| | | Bock, Christoph
Walter, Jörn
Paulsen, Martina
Lengauer, Thomas |  | CpG Island Mapping by Epigenome Prediction
In: PLoS Computational Biology [3], 1055-1070 |  |
 |  |  | Ceccherini-Silberstein, Francesca
Svicher, Valentina
Sing, Tobias
Artese, Anna
Santoro, Maria Mercedes
Forbici, Federica
Bertoli, Ada
Alcaro, Stefano
Palamara, Guido
Monforte, Antonella d'Arminio
Balzarini, Jan
Antinori, Andrea
Lengauer, Thomas
Perno, Carlo Federico |  | Characterization and structural analysis of novel mutations in human immunodeficiency virus type 1 reverse transcriptase involved in the regulation of restistance to nonnucleoside inhibitors
In: Journal of Virology [81], 11507-11519 |  |
| | | Domingues, Francisco S.
Rahnenführer, Jörg
Lengauer, Thomas | | Conformational analysis of alternative protein structures
In: Bioinformatics [23], 3131-3138 |  |
 |  |  | Flockerzi, Aline
Maydt, Jochen
Frank, Oliver
Ruggieri, Alessia
Maldener, Esther
Seifarth, Wolfgang
Medstrand, Patrik
Lengauer, Thomas
Meyerhans, Andreas
Leib-Mosch, Christine
Meese, Eckart
Mayer, Jens |  | Expression pattern analysis of transcribed HERV sequences is complicated by ex vitvo recombination
In: Retrovirology [4], 39 |  |
| | | Franke, Andre
Hampe, Jochen
Rosenstiel, Philip
Becker, Christoph
Wagner, Florian
Häsler, Robert
Little, Randall D.
Huse, Klaus
Ruether, Andreas
Balschun, Tobias
Wittig, Michael
ElSharawy, Abdou
Mayr, Gabriele
Albrecht, Mario
Prescott, Natalie J.
Onnie, Clive M.
Fournier, Hélène
Keith, Tim
Radelof, Uwe
Platzer, Matthias
Mathew, Christopher G.
Stoll, Monika
Krawczak, Michael
Nürnberg, Peter
Schreiber, Stefan | | Systematic association mapping identifies NELL1 as a novel IBD disease gene
In: PLoS ONE [2], e691.1-13 |  |
 |  |  | Hampe, Jochen
Franke, Andre
Rosenstiel, Philip
Till, Andreas
Teuber, Markus
Huse, Klaus
Albrecht, Mario
Mayr, Gabriele
De La Vega, Francisco M.
Briggs, Jason
Günther, Simone
Prescott, Natalie J.
Onnie, Clive M.
Häsler, Robert
Sipos, Bence
Fölsch, Ulrich R.
Lengauer, Thomas
Platzer, Matthias
Mathew, Christopher G.
Krawczak, Michael
Schreiber, Stefan | | A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1
In: Nature Genetics [39], 207-211 |  |
| | | Hartmann, Christoph
Antes, Iris
Lengauer, Thomas |  | IRECS: A new algorithm for the selection of most probable ensembles of side-chain conformations in protein models.
In: Protein Science [16], 1294-1307 |  |
 |  |  | Hofmann, Wolf Peter
Fernandez, B.
Herrmann, E.
Welsch, Christoph
Mihm, Ulrike
Kronenberg, B.
Feldmann, G.
Spengler, U.
Zeuzem, Stefan
Sarrazin, Christoph | | Somatic hypermutation and mRNA expression levels of the BCL-6 gene in patients with hepatitis C virus-associated lymphoproliferative diseases
In: Journal of Viral Hepatitis [14], 484-491 |  |
| | | Hofmann, Wolf Peter
Welsch, Christoph
Takahashi, Yoshitomo
Miyajima, Hiroaki
Mihm, Ulrike
Krick, Christoph
Zeuzem, Stefan
Sarrazin, Christoph | | Identification and in silico characterization of a novel compound heterozygosty associated with hereditary aceruloplasminemia
In: Scandinavian Journal of Gastroenterology [42], 1088-1094 |  |
 |  |  | Ketter, Ralf
Kim, Yoo-Jin
Storck, Simone
Rahnenführer, Jörg
Romeike, Bernd F.M.
Steudel, Wolf-Ingo
Zang, Klaus D.
Henn, Wolfram |  | Hyperdiploidy defines a distinct cytogenetic entity of meningiomas
In: Journal of Neuro-Oncology [83], 213-221 |  |
| | | Ketter, Ralf
Urbschat, Steffi
Henn, Wolfram
Feiden, Wolfgang
Beerenwinkel, Niko
Lengauer, Thomas
Steudel, Wolf-Ingo
Zang, Klaus D.
Rahnenführer, Jörg | | Application of oncogenetic trees mixtures as a biostatistical model of the clonal cytogenetic evolution of meningiomas
In: International Journal of Cancer [121], 1473-1480 |  |
 |  |  | Kupfer, Bernd
Sing, Tobias
Schüffler, Peter
Hall, Rabea
Kurz, Ralf
McKeown, Astrid
Schneweis, Karl-Eduard
Eberl, Wolfgang
Oldenburg, Johannes
Brackmann, Hans H.
Rockstroh, Jürgen K.
Spengler, Ulrich
Däumer, Martin
Kaiser, Rolf
Lengauer, Thomas
Matz, Bertfried | | Fifteen years of env C2V3C3 evolution in six individuals clonally infected with human immunodeficiency virus type 1
In: Journal of Medical Virology [79], 1629-1639 |  |
| | | Lengauer, Thomas
Sander, Oliver
Sierra, Saleta
Thielen, Alexander
Kaiser, Rolf | | Bioinformatics prediction of HIV coreceptor usage
In: Nature Biotechnology [25], 1407-1410 |  |
 |  |  | Liu, Fang
Tostesen, Eivind
Sundet, Jostein K.
Jenssen, Tor-Kristian
Bock, Christoph
Jerstad, Geir Ivar
Thilly, William G.
Hovig, Eivind |  | The human genomic melting map
In: PLoS Computational Biology [3], e93 |  |
| | | Low, Andrew J.
Dong, Winnie
Chan, Dennison
Sing, Tobias
Swanstrom, Ronald
Jensen, Mark
Pillai, Satish
Good, Benjamin
Harrigan, P. Richard | | Current V3 genotyping algorithms are inadequate for predicting X4 co-receptor usage in clinical isolates
In: AIDS [21], F19-F26 |  |
 |  |  | Mayr, Gabriele
Domingues, Francisco S.
Lackner, Peter |  | Comparative Analysis of Protein Structure Alignments
In: BMC Structural Biology [7], 1 |  |
| | | Mikeska, Thomas
Bock, Christoph
El-Maarri, Osman
Hübner, Anika
Ehrentraut, Denise
Schramm, Johannes
Felsberg, Jörg
Kahl, Philip
Büttner, Reinhard
Pietsch, Torsten
Waha, Andreas |  | Optimization of Quantitative MGMT Promoter Methylation Analysis Using Pyrosequencing and Combined Bisulfite Restriction Analysis
In: Journal of Molecular Diagnostics [9], 368-381 |  |
 |  |  | Ramírez, Fidel
Schlicker, Andreas
Assenov, Yassen
Lengauer, Thomas
Albrecht, Mario | | Computational analysis of human protein interaction networks
In: Proteomics [7], 2541-2552 |  |
| | | Salamat-Miller, Nazila
Fang, Jianwen
Seidel, Christopher W.
Assenov, Yassen
Albrecht, Mario
Middaugh, C. Russell |  | A network-based analysis of polyanion-binding proteins utilizing human protein arrays
In: Journal of Biological Chemistry [282], 10153-10163 |  |
 |  |  | Sander, Oliver
Sing, Tobias
Sommer, Ingolf
Low, Andrew J.
Cheung, Peter K.
Harrigan, P. Richard
Lengauer, Thomas
Domingues, Francisco S. |  | Structural Descriptors of gp120 V3 Loop for the Prediction of HIV-1 Coreceptor Usage
In: PLoS Computational Biology [3], 555-564 |  |
| | | Scheller, Nicoletta
Resa-Infante, Patricia
de la Luna, Susana
Galao, Rui Pedro
Albrecht, Mario
Kaestner, Lars
Lipp, Peter
Lengauer, Thomas
Meyerhans, Andreas
Díez, Juana | | Identification of PatL1, a human homolog to yeast P body component Pat1
In: Biochimica et Biophysica Acta - Molecular Cell Research [1773], 1786-1792 |  |
 |  |  | Schlicker, Andreas
Huthmacher, Carola
Ramírez, Fidel
Lengauer, Thomas
Albrecht, Mario |  | Functional evaluation of domain-domain interactions and human protein interaction networks
In: Bioinformatics [23], 859-865 |  |
| | | Schulz, Wolfgang A.
Alexa, Adrian
Jung, Volker
Hader, Christiane
Hoffmann, Michele J.
Yamanaka, Masanori
Fritzsche, Sandy
Wlazlinski, Agnes
Müller, Mirko
Lengauer, Thomas
Engers, Rainer
Florl, Andrea R.
Wullich, Bernd
Rahnenführer, Jörg |  | Factor interaction analysis for chromosome 8 and DNA methylation alterations highlights innate immune response suppression and cytoskeletal changes in prostate cancer
In: Molecular Cancer [6], 1-16 |  |
 |  |  | Sierra, Saleta
Kaiser, Rolf
Thielen, Alexander
Lengauer, Thomas |  | Genotypic coreceptor analysis.
In: European Journal of Medical Research [12], 453-462 |  |
| | | Sing, Tobias
Low, Andrew J.
Beerenwinkel, Niko
Sander, Oliver
Cheung, Peter K.
Domingues, Francisco S.
Büch, Joachim
Däumer, Martin
Kaiser, Rolf
Lengauer, Thomas
Harrigan, P. Richard | | Predicting HIV coreceptor usage on the basis of genetic and clinical covariates
In: Antiviral Therapy [12], 1097-1106 |  |
 |  |  | Skrabal, Katharina
Low, Andrew J.
Dong, Winnie
Sing, Tobias
Cheung, Peter K.
Mammano, Fabrizio
Harrigan, P. Richard |  | Determining human immunodeficiency virus coreceptor use in a clinical setting: Degree of correlation between two phenotypic assays and a bioinformatic model
In: Journal of Clinical Microbiology [45], 279-284 |  |
| | | Söderhäll, Cilla
Marenholz, Ingo
Kerscher, Tamara
Rüschendorf, Franz
Esparza-Gordillo, Jorge
Worm, Margitta
Gruber, Christoph
Mayr, Gabriele
Albrecht, Mario
Rohde, Klaus
Schulz, Herbert
Wahn, Ulrich
Hubner, Norbert
Lee, Young-Ae |  | Variants in a novel epidermal collagen gene (COL29A1) are associated with atopic dermatitis
In: PLoS Biology [5], e242.1952-1961 |  |
 |  |  | Sommer, Ingolf
Müller, Oliver
Domingues, Francisco S.
Sander, Oliver
Weickert, Joachim
Lengauer, Thomas | | Moment invariants as shape recognition technique for comparing protein binding sites
In: Bioinformatics [23], 3139-3146 |  |
| | | Steffen, Andreas
Karasz, Maximilian
Thiele, Carolin
Lengauer, Thomas
Kämper, Andreas
Wenz, Gerhard
Apostolakis, Joannis | | Combined similarity and QSPR virtual screening for guest molecules of $\beta$-cyclodextrin
In: New Journal of Chemistry [31], 1941-1949 |  |
 |  |  | Steffen, Andreas
Thiele, Carolin
Tietze, Simon
Strassnig, Christian
Kämper, Andreas
Lengauer, Thomas
Wenz, Gerhard
Apostolakis, Joannis | | Improved cyclodextrin-based receptors for camptothecin by inverse virtual screening
In: Chemistry [13], 6801-6809 |  |
| | | Tress, Michael L.
Martelli, Pier L.
Frankish, Adam
Reeves, Gabrielle A.
Wesselink, Jan J.
Yeats, Corin
Ólason, Páll Í.
Albrecht, Mario
Hegyi, Hedi
Giorgetti, Alejandro
Raimondo, Domenico
Lagarde, Julien
Laskowski, Roman A.
López, Gonzalo
Sadowski, Michael I.
Watson, James D.
Fariselli, Piero
Rossi, Ivan
Nagy, Alinda
Kai, Wang
Størling, Zenia
Orsini, Massimiliano
Assenov, Yassen
Blankenburg, Hagen
Huthmacher, Carola
Ramírez, Fidel
Schlicker, Andreas
Denoued, France
Jones, Phil
Kerrien, Samuel
Orchard, Sandra
Antonarakis, Stylianos E.
Reymond, Alexandre
Birney, Ewan
Brunak, Søren
Casadio, Rita
Guigo, Roderic
Harrow, Jennifer
Hermjakob, Henning
Jones, David T.
Lengauer, Thomas
Orengo, Christine A.
Patthy, László
Thornton, Janet M.
Tramontano, Anna
Valencia, Alfonso |  | The implications of alternative splicing in the ENCODE protein complement
In: Proceedings of the National Academy of Sciences [104], 5495-5500 |  |
 |  |  | Welker, Martin W.
Hofmann, Wolf-Peter
Welsch, Christoph
von Wagner, Michael
Herrmann, Eva
Lengauer, Thomas
Zeuzem, Stefan
Sarrazin, Christoph | | Correlation nonstructural (NS)4B amino acid variations with initial viral kinetics during interferon-alpha-based therapy in HCV-1b-infected patients
In: Journal of Viral Hepatitis [14], 338-349 |  |
| | | Welsch, Christoph
Albrecht, Mario
Maydt, Jochen
Herrmann, E.
Welker, M.W.
Sarrazin, C.
Scheidig, A.
Lengauer, Thomas
Zeuzem, S. | | Structural and functional comparison of the non-structural protein 4B of flaviviridae
In: Journal of Molecular Graphics and Modeling [26], 546-557 |  |
2 |
|
  | Electronic Journal Article |
|  |
| | | Kamradt, Jörn
Jung, Volker
Wahrheit, Kerstin
Tolosi, Laura
Rahnenführer, Jörg
Schilling, Martin
Walker, Robert
Davis, Sean
Stöckle, Michael
Meltzer, Paul
Wullich, Bernd | | Detection of Novel Amplicons in Prostate Cancer by Comprehensive Genomic Profiling of Prostate Cancer Cell Lines Using Oligonucleotide-Based ArrayCGH
In: PLoS ONE [2], e769 |  |
 |  |  | Schlicker, Andreas
Rahnenführer, Jörg
Albrecht, Mario
Lengauer, Thomas
Domingues, Francisco S. |  | GOTax: investigating biological processes and biochemical activities along the taxonomic tree
In: Genome Biology [8], R33.1-10 |  |
1 |
|
 | Journal |
|  |
 |  |  | Lengauer, Oette, Selbig, Hoffmann, Poggensee, Hamouda, Häussinger, Kaiser (ed.) | | European Journal of Medical Research |  |
10 |
|
 | Thesis - Masters thesis |
|  |
 |  |  | Bogojeska, Jasmina | | Stability analysis of oncogenetic trees mixture models
Universität des Saarlandes |  |
| | | Dietzen, Matthias | | An additive tree-based approach to the prediction of the strength of acidity for drug-like molecules
Universität des Saarlandes |  |
 |  |  | Feuerbach, Lars |  | Towards Comparative Epigenomics: A Pilot Study on DNA Methylation of CpG Islands on Human Chromosome 21
Universität des Saarlandes |  |
| | | Haid, Carla | | BSIFlex: Binding Site Identification including protein flexibility
Universität des Saarlandes |  |
 |  |  | Kircher, Martin | | In silico analysis of microRNA genes on human chromosome 14 and mouse chromosome 12
Universität des Saarlandes |  |
| | | Korbel, Ulli S. | | Identification of Symmetries in Molecules and Complexes
Universität des Saarlandes |  |
 |  |  | Müller, Oliver | | Using Shape Retrieval Techniques for Identifying Similar Protein Binding Sites
Universität des Saarlandes |  |
| | | Schelhorn, Sven-Eric | | Prediction of Domain and Motif Interactions from Protein Networks
Universität des Saarlandes |  |
 |  |  | Volkamer, Andrea | | Automated generation of pharmacophore type constraints to improve FlexX docking
Universität des Saarlandes |  |
| | | Weisser, Hendrik | | Estimating the local variance of protein structure models
Universität des Saarlandes |  |
2 |
|
|  |
| | | Blankenburg, Hagen | | A Distributed Annotation System for Molecular Interactions
Ruprecht Karl Universität Heidelberg; Universität Heilbronn |  |
 |  |  | Emig, Dorothea | | The Impact of Alternative Splicing on Protein Interaction Networks
Eberhard Karls Universität Tübingen |  |
57 |
 | 2006 |
|  |
1 |
|
|  |
| | | Bock, Christoph
Halachev, Konstantin
Lengauer, Thomas | | Bioinformatisches Data Mining erschließt neue Strategien gegen Krebs
In: Aktuelle Trends in der Softwareforschung, 91-99 |  |
3 |
|
|  |
| | | Schlicker, Andreas
Huthmacher, Carola
Ramírez, Fidel
Lengauer, Thomas
Albrecht, Mario | | Functional evaluation of domain-domain interactions and human protein interaction networks
In: German Conference on Bioinformatics (GCB 2006), 115-126 |  |
 |  |  | Steffen, Andreas
Kämper, Andreas
Lengauer, Thomas | | Virtual screening for guest molecules of a biosensor
In: Biosensors 2006: The ninth world congress on biosensors, O66 |  |
| | | Talwar, Priti
Lengauer, Thomas
Wittmann, Christoph
Velagapudi, V. R.
Heinzle, Elmar | | Development of Computational Methods for Analysis of Metabolic Profiling Data
In: Proceedings of International Conference on Systems Biology (ICSB 2006), Japan, 42-42 |  |
1 |
|
|  |
| | | Antes, Iris
Lengauer, Thomas | | Refinement of homology modeled protein structures for molecular docking
In: Proceedings of the 367. WE-Heraeus Seminar on Biomolecular Simulations, 1 |  |
29 |
|
|  |
| | | Albrecht, Mario
Takken, Frank L. W. | | Update on the domain architectures of NLRs and R proteins
In: Biochemical and Biophysical Research Communications [339], 459-462 |  |
 |  |  | Alexa, Adrian
Rahnenführer, Jörg
Lengauer, Thomas |  | Improved Scoring of Functional Groups from Gene Expression Data by Decorrelating GO Graph Structure
In: Bioinformatics [22], 1600-1607 |  |
| | | Antes, Iris
Siu, Shirley Weng-In
Lengauer, Thomas |  | DynaPred: A structure and sequence based method for the prediction of MHC class I binding peptide sequence and conformations
In: Bioinformatics [22], 16-24 |  |
 |  |  | Bock, Christoph | | Bioinformatik: Neue Strategien gegen Krebs
In: Deutsches Ärzteblatt PRAXiS [103], 10-11 |  |
| | | Bock, Christoph
Hesser, Jürgen |  | Analysis and Prediction of Helix Shift Errors in Homology Modeling
In: In Silico Biology [6], 131-145 |  |
 |  |  | Boeddrich, Annett
Gaumer, Sébastien
Haacke, Annette
Tzvetkov, Nikolay
Albrecht, Mario
Evert, Bernd O.
Müller, Eva C.
Lurz, Rudi
Breuer, Peter
Schugardt, Nancy
Plaßmann, Stephanie
Xu, Kexiang
Warrick, John M.
Suopanki, Jaana
Wüllner, Ullrich
Frank, Ronald
Hartl, Ulrich F.
Bonini, Nancy M.
Wanker, Erich E. | | An arginine/lysine-rich motif is crucial for VCP/p97-mediated modulation of ataxin-3 fibrillogenesis
In: EMBO Journal [25], 1547-1558 |  |
| | | Heckmann-Pohl, Dorothee M.
Bastian, Sabine
Altmeier, S.
Antes, Iris | | Improvement of the fungal enzyme pyranose 2-oxidase using protein engineering
In: Journal of Biotechnology [124], 26-40 |  |
 |  |  | Heil, Burkhard
Ludwig, Jost
Lichtenberg-Fraté, Hella
Lengauer, Thomas | | Computational recognition of potassium channel sequences
In: Bioinformatics [13], 1562-1568 |  |
| | | Kämper, Andreas
Apostolakis, Joannis
Rarey, Matthias
Marian, Christel Maria
Lengauer, Thomas | | Fully Automated Flexible Docking of Ligands into Flexible Synthetic Receptors Using Forward and Inverse Docking Strategies
In: Journal of Chemical Information and Modeling [46], 903-911 |  |
 |  |  | Lehmann, Clara
Däumer, Martin
Bousaad, Ibrahim
Sing, Tobias
Beerenwinkel, Niko
Lengauer, Thomas
Schmeisser, Norbert
Wyen, Christoph
Fätkenheuer, Gerd
Kaiser, Rolf | | Stable coreceptor usage of HIV in patients with ongoing treatment failure on HAART
In: Journal of Clinical Virology [37], 300-304 |  |
| | | Lengauer, Thomas
Domingues, F.S.
Sommer, Ingolf
Zhu, Hongbo | | Analysis and prediction of protein-protein-interaction types
In: BMC Bioinformatics [7], - |  |
 |  |  | Lengauer, Thomas
Sing, Tobias | | Bioinformatics-assisted anti-HIV therapy
In: Nature Reviews Microbiology [4], 790-797 |  |
| | | Maydt, Jochen
Lengauer, Thomas | | Recco: recombination analysis using cost optimization
In: Bioinformatics [22], 1064-1071 |  |
 |  |  | Mihm, Ulrike
Grigorian, Natalia
Welsch, Christoph
Herrmann, Eva
Kronenberger, Bernd
Teuber, Gerlinde
von Wagner, Michael
Hofmann, Wolf-Peter
Albrecht, Mario
Lengauer, Thomas
Zeuzem, Stefan
Sarrazin, Christoph | | Amino acid variations in hepatitis C virus p7 and sensitivity to antiviral combination therapy with amantadine in chronic hepatitis C
In: Antiviral Therapy [11], 507-519 |  |
| | | Neumann, Dirk
Kohlbacher, Oliver
Merkwirth, Christian
Lengauer, Thomas | | A Fully Computational Model for Predicting Percutaneous Drug Absorption
In: Journal of Chemical Information and Modeling [1], 424-429 |  |
 |  |  | Neumann, Dirk
Kohlbacher, Oliver
Merkwirth, Christian
Lengauer, Thomas | | Prediction of percutaneous drug absorption
In: Journal of Chemical Information and Modeling [1], 424-429 |  |
| | | Plotz, Guido
Welsch, Christoph
Giron-Monzon, Luis
Friedhoff, Peter
Albrecht, Mario
Piiper, Albrecht
Biondi, Ricardo M.
Lengauer, Thomas
Zeuzem, Stefan
Raedle, Jochen |  | Mutations in the MutSalpha interaction interface of MLH1 can abolish DNA mismatch repair
In: Nucleic Acids Research [34], 6574-6586 |  |
 |  |  | Roomp, Kirsten
Beerenwinkel, Niko
Sing, Tobias
Schülter, Eugen
Büch, Joachim
Sierra-Aragon, Saleta
Däumer, Martin
Hoffmann, Daniel
Kaiser, Rolf
Lengauer, Thomas
Selbig, Joachim | | Arevir: A Secure Platform for Designing Personalized Antiretroviral Therapies Against HIV
In: Lecture Notes in Computer Science [4075], 185-194 |  |
| | | Salamat-Miller, Nazila
Fang, Jianwen
Seidel, Christopher W.
Smalter, Aaron M.
Assenov, Yassen
Albrecht, Mario
Middaugh, C. Russell | | A network-based analysis of polyanion-binding proteins utilizing yeast protein arrays
In: Molecular and Cellular Proteomics [5], 2263-2278 |  |
 |  |  | Sing, Tobias
Sander, Oliver
Beerenwinkel, Niko
Lengauer, Thomas | | ROCR: Visualizing classifier performance in R
In: Bioinformatics [21], 3940-3941 |  |
| | | Steffen, Andreas
Kämper, Andreas
Lengauer, Thomas | | Flexible Docking of Ligands into Synthetic Receptors Using a Two-Sided Incremental Construction Algorithm
In: Journal of Chemical Information and Modeling [46], 1695-1703 |  |
 |  |  | Svicher, Valentina
Sing, Tobias
Santoro, Maria Mercedes
Forbici, Federica
Rodriguez- Barrios, Fátima
Bertoli, Ada
Beerenwinkel, Niko
Bellocchi, Maria Concetta
Gago, Federigo
d´Arminio Monforte, Antonella
Antinori, Andrea
Lengauer, Thomas
Ceccherini-Silberstein, Francesca
Perno, Carlo-Federico | | Involvement of novel HIV-1 reverse transcriptase mutations in the regulation of resistance to nucleoside inhibitors
In: Journal of Virology [80], 7186-7198 |  |
| | | Takken, Frank L. W.
Albrecht, Mario
Tameling, Wladimir I. | | Resistance proteins: molecular switches of plant defence
In: Current Opinion in Plant Biology [9], 383-390 |  |
 |  |  | Tameling, Wladimir I.
Vossen, Jack H.
Albrecht, Mario
Lengauer, Thomas
Berden, Jan A.
Haring, Michel A.
Cornelissen, Ben J.C.
Takken, Frank L. W. | | Mutations in the NB-ARC domain of I-2 that impair ATP hydrolysis cause autoactivation
In: Plant Physiology [140], 1233-1245 |  |
| | | Torda, Andrew E.
Lengauer, Thomas |  | Editorial: Selection of papers of the German Conference of Bioinformatics (GCB) 2005
In: Bioinformatics [22], 1 |  |
 |  |  | Velagapudi, Vidya R.
Wittmann, Christoph
Lengauer, Thomas
Talwar, Priti
Heinzle, Elmar | | Metabolic high- content screening of Saccharomyces cerevisiae reveals superior performance of single gene deletion strains
In: Process Biochemistry [41], 2170-2179 |  |
| | | Verheyen, Jens
Litau, Elena
Sing, Tobias
Däumer, Martin
Balduin, Melanie
Oette, Mark
Fätkenheuer, Gerd
Rockstroh, Jürgen K.
Schuldenzucker, Ulrike
Hoffmann, Daniel
Pfister, Herbert
Kaiser, Rolf | | Compensatory mutations at the HIV cleavage sites p7/p1 and p1/p6-gag in therapy-naive and therapy-experienced patients
In: Antiviral Therapy [11], 879-887 |  |
 |  |  | Voets, Marieke
Antes, Iris
Scherer, Christiane
Müller-Vieira, Ursula
Biemel, Klaus
Marchais-Oberwinkler, Sandrine
Hartmann, Rolf W. | | Synthesis and evaluation of heteroaryl substituted dihydronaphthalenes and indenes: potent and selective inhibitors of aldosterone synthase (CYP11B2) for the treatment of congestive heart failure and myocardial fibrosis
In: Journal of Medicinal Chemistry [49], 2222-2231 |  |
| | | Yin, Junming
Beerenwinkel, Niko
Rahnenführer, Jörg
Lengauer, Thomas |  | Model Selection for Mixtures of Mutagenetic Trees
In: Statistical Applications in Genetics and Molecular Biology [5], Article 17 |  |
5 |
|
  | Electronic Journal Article |
|  |
| | | Bock, Christoph
Paulsen, Martina
Tierling, Sascha
Mikeska, Thomas
Lengauer, Thomas
Walter, Jörn |  | CpG Island Methylation in Human Lymphocytes Is Highly Correlated with DNA Sequence, Repeats, and Predicted DNA Structure
In: PLoS Genetics [2], 0243-0252 |  |
 |  |  | Sander, Oliver
Sommer, Ingolf
Lengauer, Thomas | | Local protein structure prediction using discriminative models
In: BMC Bioinformatics [7], 1-13 |  |
| | | Schlicker, Andreas
Domingues, Francisco S.
Rahnenführer, Jörg
Lengauer, Thomas |  | A new measure for functional similarity of gene products based on Gene Ontology
In: BMC Bioinformatics [7], 1-16 |  |
 |  |  | Sommer, Ingolf
Toppo, Stefano
Sander, Oliver
Lengauer, Thomas
Tosatto, Silvio C. E. | | Improving the quality of protein structure models by selecting from alignment alternatives
In: BMC Bioinformatics [7], 1-11 |  |
| | | Zhu, Hongbo
Domingues, Francisco S.
Sommer, Ingolf
Lengauer, Thomas | | NOXclass: prediction of protein-protein interaction types
In: BMC Bioinformatics [7], 1-15 |  |
7 |
|
|  |
| | | Frings, Oliver | | Development of a
Smith-Waterman-Like Multi-Aspect
Alignment Tool
Universität des Saarlandes |  |
 |  |  | Glaab, Enrico | | On the predictability of CpG methylation in human tissue at single basepair resolution
Universität des Saarlandes |  |
| | | Hobler, Anna | | Docking of monosaccharids into the wild type and mutants of pyranose 2-oxidase
Universität des Saarlandes |  |
 |  |  | Jung, Holger | | Yamada Analyzer - A tool for fast calculation of genomic attributes
Universität des Saarlandes |  |
| | | Pfeifer, Susanne | | Development of a fast
geometry-based screening
compound prefiltering technique
Universität des Saarlandes |  |
 |  |  | Reimer, Daniela | | Docking studies to investigate the effect of correlated mutations in the HIV-Protease on the drug resistance of HIV
Universität des Saarlandes |  |
| | | Zimmer, Tobias | | Functional Site Scaffolds
Universität des Saarlandes |  |
8 |
|
|  |
| | | Assenov, Yassen | | Topological Analysis of Biological
Networks
Universität des Saarlandes |  |
 |  |  | Binsl, Thomas | | Feature Prints: A new method for calculating molecular similarities
Universität des Saarlandes |  |
| | | Guo, Xin | | Improving Fold Recognition Using Protein
and Domain Interactions
Universität des Saarlandes |  |
 |  |  | Halachev, Konstantin | | EpiGRAPHregression: A toolkit for (epi-)genomic correlation analysis and prediction of quantitative attributes
Universität des Saarlandes |  |
| | | Kaspar, Melanie | | Automated conformational analysis of macrocyclic ring systems
Universität des Saarlandes |  |
 |  |  | Thielen, Alexander | | Prediction of linear B-cell epitopes and MHC class II binding peptides
Eberhardt-Karls-Universität Tübingen |  |
| | | Tolosi, Laura | | Analysis of Array CGH Data for the Estimation of Genetic Tumor Progression
Universität des Saarlandes |  |
 |  |  | Weinhold, Nils | | Inference of Protein Function based on Functionally Conserved Regions in Sequence and Structure Space
Universität des Saarlandes |  |
1 |
|
 | Thesis - PhD thesis |
|  |
 |  |  | Albrecht, Mario | | Combining protein structure prediction with experiments and functional information
Universität des Saarlandes |  |
1 |
|
 | Thesis - Habilitation thesis |
|  |
 |  |  | Rahnenführer, Jörg | | Statistical methods for the biological interpretation of genome-wide measurements
Universität des Saarlandes |  |
1 |
|
 | Thesis - other |
|  |
 |  |  | Huthmacher, Carola | | Decomposing Protein Networks Into
Domain-Domain Interactions
Eberhard Karls University Tübingen |  |
57 |
 | 2005 |
|  |
1 |
|
|  |
| | | Lengauer, Thomas |  | Informatics (Computational Biology)
In: Growth Factors and Oncogenes in Gastrointestinal Cancers to Informatics (Computational Biology), 567-626 |  |
6 |
|
|  |
| | | Kaiser, Rolf
Boussaad, Ibo
Lehmann, C.
Däumer, Martin
Sing, Tobias
Schmeisser, N.
Wyen, C.
Fätkenheuer, Gerd | | Stable coreceptor usage of HIV-1 in patients with ongoing treatment failure on HAART
In: Proceedings of the 3rd European HIV Drug Resistance Workshop, - |  |
 |  |  | Kämper, Andreas
Kaspar, Melanie
Lengauer, Thomas | | Efficient conformational analysis of synthetic receptors with macrocyclic and fused ring systems
In: Synthetic Receptors 2005: Second World Congress on Synthetic Receptors, O4 |  |
| | | Sing, Tobias
Svicher, Valentina
Beerenwinkel, Niko
Ceccherini-Silberstein, Francesca
Däumer, Martin
Kaiser, Rolf
Walter, Hauke
Korn, Klaus
Hoffmann, Daniel
Oette, Mark
Rockstroh, Jürgen K.
Fätkenheuer, Gerd
Perno, Carlo-Federico
Lengauer, Thomas | | Characterization of novel HIV Drug Resistance Mutations using clustering, multidimensional scaling and SVM-based feature ranking
In: Knowledge Discovery in Databases: PKDD 2005., 285-296 |  |
 |  |  | Steffen, Andreas
Kämper, Andreas
Lengauer, Thomas | | FlexR - A new tool for predicting the structure of synthetic host-guest complexes
In: Synthetic Receptors 2005: Second World Congress on Synthetic Receptors, O7 |  |
| | | Svicher, Valentina
Ceccherini-Silberstein, Francesca
Sing, Tobias
Santoro, Maria Mercedes
Gori, C.
Beerenwinkel, Niko
Gago, F.
D'Arrigo, R.
Bellocchi, M. C.
Giannella, S.
Bertoli, A.
D'Arminio Monforte, A.
Antinori, A.
Perno, Carlo-Federico | | Additional Mutations in HIV-1 Reverse Transcriptase are Involved in the Highly Ordered Regulation of NRTI Resistance
In: Proceedings of the 3rd European HIV Drug Resistance Workshop, - |  |
 |  |  | Svicher, Valentina
Ceccherini-Silberstein, Francesca
Sing, Tobias
Santoro, Maria Mercedes
Gori, C.
Beerenwinkel, Niko
Gago, F.
D'Arrigo, R.
Bellochi, M.C.
Giannella, S.
Bertoli, A.
D'Arminio Monforte, A.
Antinori, A.
Perno, Carlo-Federico | | A highly ordered network of HIV-1 RT mutations regulates the continuous escape from antiviral drugs
In: International Workshop in HIV Dynamics and Evolution, - |  |
4 |
|
 | Poster |
|  |
 |  |  | Sing, Tobias
Beerenwinkel, Niko
Kaiser, Rolf
Hoffmann, Daniel
Däumer, Martin
Lengauer, Thomas | | Geno2pheno[coreceptor]: a tool for predicting coreceptor usage from genotype and for monitoring coreceptor-associated sequence alterations
In: Proceedings of the 3rd European HIV Drug Resistance Workshop, - |  |
| | | Talwar, Priti
Lengauer, Thomas
Rahnenführer, Jörg
Heinzle, Elmar
Velagapudi, VR
Wittmann, Christoph | | Towards computational analysis of metabolic profiling data for protein function prediction.
In: Proceedings of the Yeast Systems Biology, 6th International Conference on Systems Biology (ICSB 2005), 1 |  |
 |  |  | Talwar, Priti
Lengauer, Thomas
Rahnenführer, Jörg
Wittmann, Christoph
Velagapudi, VR
Heinzle, Elmar | | Computational Methods for Protein Function Prediction using Metabolomics Data
In: Proceedings of International Workshop on Systems Biology 2005, 1 |  |
| | | Zhu, Hongbo
Domingues, Francisco S.
Sommer, Ingolf
Lengauer, Thomas | | Analysis and prediction of protein-protein interaction types
In: 4th European Conference on Computational Biology (ECCB05), 1 |  |
32 |
|
|  |
| | | Albrecht, Mario | | LRRK2 mutations and parkinsonism
In: The Lancet [365], 1230 |  |
 |  |  | Albrecht, Mario
Choubey, Divaker
Lengauer, Thomas | | The HIN domain of IFI-200 proteins consists of two OB folds
In: Biochemical and Biophysical Research Communications [327], 679-687 |  |
| | | Albrecht, Mario
Huthmacher, Carola
Tosatto, Silvio C.E.
Lengauer, Thomas | | Decomposing protein networks into domain-domain interactions
In: Bioinformatics [21], ii220-ii221 |  |
 |  |  | Antes, Iris
Merkwirth, Christian
Lengauer, Thomas | | POEM: Parameter Optimization using Ensemble Methods: Application to target specific scoring functions
In: Journal of Chemical Information and Modeling [45], 1291-1302 |  |
| | | Balduin, Melanie
Beerenwinkel, Niko
Sierra, Saleta
Däumer, Martin
Rockstroh, Jürgen
Oette, Mark
Fätkenheuer, Gerd
Kupfer, Bernd
Hoffmann, Daniel
Selbig, Joachim
Pfister, Herbert
Kaiser, Rolf | | Evolution of HIV resistance during treatment interruption in experienced patients and after restarting a new therapy
In: J Clin Virol [34], 277-287 |  |
 |  |  | Beerenwinkel, Niko
Däumer, Martin
Sing, Tobias
Rahnenführer, Jörg
Lengauer, Thomas
Selbig, Joachim
Hoffmann, Daniel
Kaiser, Rolf | | Estimating HIV evolutionary pathways and the genetic barrier to drug resistance
In: The Journal of Infectious Diseases [191], 1953-1960 |  |
| | | Beerenwinkel, Niko
Rahnenführer, Jörg
Däumer, Martin
Hoffmann, Daniel
Kaiser, Rolf
Selbig, Joachim
Lengauer, Thomas | | Learning multiple evolutionary pathways from cross-sectional data
In: Journal of Computational Biology [12], 584-598 |  |
 |  |  | Beerenwinkel, Niko
Rahnenführer, Jörg
Kaiser, Rolf
Hoffmann, Daniel
Selbig, Joachim
Lengauer, Thomas | | Mtreemix: a software package for learning and using mixture models of mutagenetic trees
In: Bioinformatics [21], 2106-2107 |  |
| | | Beerenwinkel, Niko
Sing, Tobias
Lengauer, Thomas
Rahnenführer, Jörg
Roomp, Kirsten
Savenkov, Igor
Fischer, Roman
Hoffmann, Daniel
Selbig, Joachim
Korn, Klaus
Walter, Hauke
Berg, Thomas
Braun, Patrick
Fätkenheuer, Gerd
Oette, Mark
Rockstroh, Jürgen
Kupfer, Bernd
Kaiser, Rolf
Däumer, Martin | | Computational methods for the design of effective therapies against drug resistant HIV strains
In: Bioinformatics [21], 3943-3950 |  |
 |  |  | Bock, Christoph
Lengauer, Thomas
Reither, Sabine
Mikeska, Thomas
Paulsen, Martina
Walter, Jörn |  | BiQ Analyzer: visualization and quality control for DNA methylation data from bisulfite sequencing
In: Bioinformatics [21], 4067-4068 |  |
| | | Bojunga, Jörg
Welsch, Christoph
Antes, Iris
Albrecht, Mario
Lengauer, Thomas
Zeuzem, Stefan | | Structural and functional analysis of a novel mutation of CYP21B in a heterozygote carrier of 21-hydroxylase deficiency
In: Human Genetics [117], 558-564 |  |
 |  |  | Castellano, Sergi
Lobanov, Alexey V.
Chapple, Charles
Novoselov, Sergey V.
Albrecht, Mario
Hua, Deame
Lescure, Alain
Lengauer, Thomas
Krol, Alain
Gladyshev, Vadim N.
Guigó, Roderic | | Diversity and functional plasticity of eukaryotic selenoproteins: Identification and characterization of the SelJ family
In: Proceedings of the National Academy of Sciences [102], 16188-16193 |  |
| | | Costello, Christine M.
Mah, Nancy
Häsler, Robert
Rosenstiel, Philip
Waetzig, Georg H.
Hahn, Andreas
Lu, Tim
Gurbuz, Yesim
Nikolaus, Susanna
Albrecht, Mario
Hampe, Jochen
Lucius, Ralph
Klöppel, Günther
Eickhoff, Holger
Lehrach, Hans
Lengauer, Thomas
Schreiber, Stefan | | Dissection of the inflammatory bowel disease transcriptome using genome-wide cDNA microarrays identifies novel candidate disease genes
In: PLoS Medicine [2], 771-787 |  |
 |  |  | Das, Ani V.
James, Jackson
Rahnenführer, Jörg
Thoresona, Wallace B.
Bhattacharyaa, Sumitra
Zhao, Xing
Ahmad, Iqbal | | Retinal properties and potential of the adult mammalian ciliary epithelium stem cells
In: Vision Research [45], 1653-1666 |  |
| | | Gu, Wei
Kofler, Michael
Antes, Iris
Freund, Christian
Helms, Volkhard | | Alternative Binding Modes of Polyproline Peptides Binding to the GYF Domain
In: Biochemistry [44], 6404-6415 |  |
 |  |  | Hahn, Andreas
Rahnenführer, Jörg
Talwar, Priti
Lengauer, Thomas | | Confirmation of human protein interaction data by human expression data
In: BMC Bioinformatics [6], 1-11 |  |
| | | Hessler, G.
Zimmermann, M.
Matter, H.
Evers, A.
Naumann, T.
Lengauer, Thomas
Rarey, M. | | Multiple-Ligand-Based Virtual Screening: Methods and Applications of the MTree Approach
In: Journal of Medicinal Chemistry [48], 6575-6584 |  |
 |  |  | Lengauer, Thomas
Albrecht, Mario
Sarrazin, C.
Mihm, U.
Herrmann, E.
Welsch, Christoph
Sarrazin, U.
Traver, S.
Zeuzem, S. | | Clinical significance of in vitro replication-enhancing mutations of the hepatitis C virus (HCV) replicon in patients with chronic HCV infection.
In: Journal of Infectious Diseases [192], 1710-1719 |  |
| | | Lengauer, Thomas
Merkwirth, Christian | | Automatic Generation of complementary descriptors with molecular graph networks
In: Journal of Chemical Information and Modeling [45], 1159-1168 |  |
 |  |  | Rahnenführer, Jörg | | Clustering algorithms and other exploratory methods for microarray data analysis
In: Methods of Information in Medicine [44], 444-448 |  |
| | | Rahnenführer, Jörg | | Image analysis for cDNA microarrays
In: Methods of Information in Medicine [44], 405-407 |  |
 |  |  | Rahnenführer, Jörg
Beerenwinkel, Niko
Schulz, Wolfgang A.
Hartmann, Christian
von Deimling, Andreas
Wullich, Bernd
Lengauer, Thomas | | Estimating cancer survival and clinical outcome based on genetic tumor progression scores
In: Bioinformatics [21], 2438-2446 |  |
| | | Ralser, Markus
Albrecht, Mario
Nonhoff, Ute
Lengauer, Thomas
Lehrach, Hans
Krobitsch, Sylvia | | An integrative approach to gain insights into the cellular function of human ataxin-2
In: Journal of Molecular Biology [346], 203-214 |  |
 |  |  | Ralser, Markus
Nonhoff, Ute
Albrecht, Mario
Lengauer, Thomas
Wanker, Erich E.
Lehrach, Hans
Krobitsch, Sylvia | | Ataxin-2 and huntingtin interact with endophilin-A complexes to function in plastin-associated pathways
In: Human Molecular Genetics [14], 2893-2909 |  |
| | | Sarrazin, Christoph
Mihm, Ulrike
Herrmann, Eva
Welsch, Christoph
Albrecht, Mario
Sarrazin, Ulrike
Traver, Stella
Lengauer, Thomas
Zeuzem, Stefan | | Clinical significance of in vitro replication-enhancing mutations of the hepatitis C virus (HCV) replicon in patients with chronic HCV infection
In: The Journal of Infectious Diseases [192], 1710-1719 |  |
 |  |  | Schreiber, Stefan
Rosenstiel, Philip
Albrecht, Mario
Hampe, Jochen
Krawczak, Michael | | Genetics of Crohn disease, an archetypal inflammatory barrier disease
In: Nature Reviews Genetics [6], 376-388 |  |
| | | Ulmschneider, Sarah
Mueller-Vieira, Ursula
Klein, Christian D.
Antes, Iris
Lengauer, Thomas
Hartmann, Rolf W. | | Synthesis and Evaluation of Pyridylmethylene-tetrahydronaphthalenes and -indanes: Potent and Selective Inhibitors of Aldosterone Synthase (CYP11B2)
In: Journal of Medicinal Chemistry [48], 4489-4490 |  |
 |  |  | Ulmschneider, Sarah
Mueller-Vieira, Ursula
Mitrenga, Markus
Hartmann, Rolf W.
Oberwinkler-Marchais, S
Klein, Christian D.
Bureik, M.
Bernhardt, R.
Antes, Iris
Lengauer, Thomas | | Synthesis and Evaluation of Imidazolylmethylenetetrahydronaphthalenes and Imidazolylmethyleneindanes: Potent Inhibitors of Aldosterone Synthase
In: Journal of Medicinal Chemistry [48], 1796-1805 |  |
| | | Valentonyte, Ruta
Hampe, Jochen
Huse, Klaus
Rosenstiel, Philip
Albrecht, Mario
Stenzel, Annette
Nagy, Marion
Gaede, Karoline I.
Franke, Andre
Haesler, Robert
Koch, Andreas
Lengauer, Thomas
Seegert, Dirk
Reiling, Norbert
Ehlers, Stefan
Schwinger, Eberhard
Platzer, Mathias
Krawczak, Michael
Müller-Quernheim, Joachim
Schürmann, Manfred
Schreiber, Stefan | | Sarcoidosis is associated with a truncating splice site mutation in BTNL2
In: Nature Genetics [37], 357-364 |  |
 |  |  | Van Duist, Marjan M.
Albrecht, Mario
Podswiadek, Marta
Giachino, Daniela
Lengauer, Thomas
Punzi, Leonardo
De Marchi, Mario | | A new CARD15 mutation in Blau syndrome
In: European Journal of Human Genetics [13], 742-747 |  |
| | | Voets, Marieke
Antes, Iris
Scherer, C
Mueller-Vieira, U.
Biemel, K.
Barrassin, C.
Marchais-Oberwinkler, S.
Hartmann, R. W. | | Heteroaryl-substituted naphthalenes and structurally modified derivatives: selective inhibitors of CYP11B2 for the treatment of congestive heart failure and myocardial fibrosis
In: Journal of Medicinal Chemistry [48], 6632-6642 |  |
 |  |  | Wemmert, Silke
Ketter, Ralf
Rahnenführer, Jörg
Beerenwinkel, Niko
Strowitzki, Martin
Feiden, Wolfgang
Hartmann, Christian
Lengauer, Thomas
Stockhammer, Florian
Zang, Klaus D.
Meese, Eckart
Steudel, Wolf-Ingo
von Deimling, Andreas
Urbschat, Steffi |  | Patients with high grade gliomas harboring delections of chromosomes 9p and 10q benefit from temozolomide treatment
In: Neoplasia [7], 883-893 |  |
9 |
|
 | Thesis - Bachelor thesis |
|  |
 |  |  | Djoumbou, Yannick | | Docking studies to investigate the effect of correlated mutations in the HIV-Protease on the drug resistance of HIV
Universität des Saarlandes |  |
| | | Immesberger, Stefan |  | A Prefiltering Method to Speed up Protein
Structure Prediction
Universität des Saarlandes |  |
 |  |  | Kaspar, Melanie |  | Conformational Analysis of Macrocyclic Ring Systems
Universität des Saarlandes |  |
| | | Krier, Markus |  | Motif Search in Protein Sequences for Protein
Structure Prediction
Universität des Saarlandes |  |
 |  |  | Meiser, Ina | | Identification of functionally important regions in cytochrome P450 systems and a systematic analysis of various CYP P450 homology models
Universität des Saarlandes |  |
| | | Nickels, Stefan |  | Generating Molecular Hashcodes for
Finding Duplicates in Virtual Screening
Libraries
Universität des Saarlandes |  |
 |  |  | Volkamer, Andrea |  | Implementation of a method to filter
out compounds with toxic, reactive
and unsuitable functional groups
Universität des Saarlandes |  |
| | | Weiss, Julia |  | Generating Frequency Profiles from Multiple
Structure Alignments
Universität des Saarlandes |  |
 |  |  | Yalak, Garif |  | Analysis of Mutations in the Death Domains, Death Effector Domains, Caspase
Recruitment Domains, and Pyrin Domains
Universität des Saarlandes |  |
5 |
|
 | Thesis - Masters thesis |
|  |
 |  |  | Alexa, Adrian | | Integrating the GO graph structure in scoring the
significance of Gene Ontology terms
Universität des Saarlandes |  |
| | | Ifrim, Georgiana | | A Bayesian Learning Approach to Concept-Based Document Classification
Universität des Saarlandes |  |
 |  |  | Schlicker, Andreas | | A Global Approach to Comparative Genomics: Comparison of Functional Annotation over the Taxonomic Tree
Universität des Saarlandes |  |
| | | Siu, Shirley Weng-In | | Computational prediction of MHC-peptide interactions
Universität des Saarlandes |  |
 |  |  | Yin, Junming | | Model Selection for Mixtures of Mutagenetic Trees
Universität des Saarlandes |  |
41 |
 | 2004 |
|  |
1 |
|
|  |
| | | Beerenwinkel, Niko | | Computational Analysis of HIV Drug resistance Data |  |
4 |
|
|  |
| | | Beerenwinkel, Niko | | Das Arevir-Projekt : neue Wege zur Optimierung von Anti-HIV-Therapien
In: Resistenz in der HIV-Therapie : Diagnostik und Management, 94-98 |  |
 |  |  | Beerenwinkel, Niko | | Methoden zur Interpretation genotypischer Resistenztests
In: Resistenz in der HIV-Therapie : Diagnostik und Management, 66-68 |  |
| | | Domingues, Francisco S.
Lengauer, Thomas
Sommer, Ingolf | | Protein Structure Prediction and Databases
In: Nature Encyclopedia of the Human Genome, 864-867 |  |
 |  |  | Ramírez, Fidel | | Evolucion de la Evolucionalidad
In: Biologos lejos del equilibrio: Nuevas metaforas evolutivas, 59-87 |  |
1 |
|
 | Proceedings |
|  |
 |  |  | Thornton, Bourne, Gilbert, Goble, Goldman, Gribskov, Hide, Higgins, Kanehisa, Lengauer, Linial, Myers, Quackenbush, Rebholz-Schuhmann, Rost, Sowdhamini, Valencia, Vingron, Xu (ed.) | | Proceedings Twelfth International Conference on Intelligent Systems for Molecular Biology/Third European Conference on Computional Biology 2004 (ISMB/ECCB 2004) |  |
5 |
|
 | Proceedings Article |
|  |
 |  |  | Beerenwinkel, Niko
Rahnenführer, Jörg
Däumer, Martin
Hoffmann, Daniel
Kaiser, Rolf
Selbig, Joachim
Lengauer, Thomas | | Learning multiple evolutionary pathways from cross-sectional data
In: RECOMB 2004 : proceedings of the Eighth Annual International Conference on Research in Computational Molecular Biology, 36-44 |  |
| | | Beerenwinkel, Niko
Sing, Tobias
Däumer, Martin
Kaiser, Rolf
Lengauer, Thomas | | Computing the genetic barrier
In: XII International HIV Drug resistance Workshop, S125-S125 |  |
 |  |  | Merkwirth, Christian
Bröcker, J.
Ogorzalek, Maciej
Wichard, J.D. | | Finite iteration DT-CNN - new design and operation principles
In: Proceedings (ISCAS-04) : 2004 IEEE International Symposium on Circuits and Systems. - Vol. 5, Blind signal processing, computer-aided network design, invited sessions, neural sytems and applications, power systems and power electronic circuits, 504-507 |  |
| | | Sing, Tobias
Beerenwinkel, Niko
Lengauer, Thomas | | Learning mixtures of localized rules by maximizing the area under the ROC curve
In: ROCAI-2004: 1st International Workshop on ROC Analysis in Artificial Intelligence, 89-96 |  |
 |  |  | Wichard, J.D.
Ogorzalek, Maciej
Merkwirth, Christian
Bröcker, J. | | Finite iteration DT-CNN with stationary templates
In: Proceedings of the 8th IEEE International Workshop on Cellular Neural Networks and their Applications (CNNA 2004), 459-464 |  |
5 |
|
 | Poster |
|  |
 |  |  | Hahn, Andreas
Costello, Christine M.
Lu, Tim
Lengauer, Thomas
Schreiber, Stefan | | Expression analysis for inflammatory bowel disease
In: Workshop Poster Competition, ? |  |
| | | Steffen, Andreas
Kämper, Andreas
Lengauer, Thomas | | Development of a new tool for predicting the structure of host-guest complexes
In: Proceedings of the 2nd Summer School Medicinal Chemistry Regensburg 2004, 83 |  |
 |  |  | Steffen, Andreas
Kämper, Andreas
Lengauer, Thomas | | FlexR - Predicting the structure of host-guest complexes
In: Proceedings of the Annual Meeting of the German Pharmaceutical Society - Joint Meeting 2004 (DPhG 2004), 130 |  |
| | | Talwar, Priti
Lengauer, Thomas
Rahnenführer, Jörg
Velagapudi, VR
Wittmann, Christoph
Heinzle, Elmar | | Computational Methods For Metabolite Screening
In: Proceedings of the 12th International Conference on Intelligent Systems for Molecular Biology + 3rd European Conference on Computational Biology (ISMB/ECCB 2004), 1 |  |
 |  |  | Talwar, Priti
Lengauer, Thomas
Rahnenführer, Jörg
Velagapudi, VR
Wittmann, Christoph
Heinzle, Elmar | | Computational Methods For Metabolite Screening
In: Proceedings of the 5th International Conference on Systems Biology (ICSB 2004), 1 |  |
16 |
|
 | Journal Article |
|  |
 |  |  | Albrecht, Mario
Golatta, Michael
Wüllner, Ullrich
Lengauer, Thomas | | Structural and functional analysis of ataxin-2 and ataxin-3
In: European Journal of Biochemistry [271], 3155-3170 |  |
| | | Albrecht, Mario
Lengauer, Thomas | | Novel Sm-like proteins with long C-terminal tails and associated methyltransferases
In: FEBS Letters [569], 18-26 |  |
 |  |  | Albrecht, Mario
Lengauer, Thomas | | Survey on the PABC recognition motif PAM2
In: Biochemical and Biophysical Research Communications [316], 129-138 |  |
| | | Crass, T.
Antes, Iris
Basekow, R.
Bork, P.
Buning, Christian
Christensen, M.
Claußen, H.
Ebeling, C.
Ernst,P.
Gailus-Durner, V.
Glatting, K.-H.
Gohla, R.
Gößling, F.
Grote, K.
Heidtke, K.
Herrmann, A.
O Keefe, S.
Kießlich, O.
Kolibal, S.
Korbel, J.O.
Lengauer, Thomas
Liebich, I.
van der Linden, M.
Luz, H.
Meissner, K.
von Mering, C.
Mevissen, T.
Mewes, H.-W.
Michael, H.
Mokrejs, M.
Müller, T.
Pospisil, H.
Rarey, Matthias
Reich, J.G.
Schneider, R.
Schomburg, D.
Schulze-Kremer, S.
Schwarzer, K.
Sommer, Ingolf
Springstubbe, S.
Suhai, S.
Thoppae, G.
Vingron, M.
Warfsmann, J.
Werner, T.
Wetzler, D.
Wingender, E.
Zimmer, Ralf | | The Helmholtz Network for Bioinformatics: an integrative web portal for bioinformatics resources
In: Bioinformatics [20], 268-270 |  |
 |  |  | Domingues, Francisco S.
Rahnenführer, Jörg
Lengauer, Thomas | | Automated clustering of ensembles of alternative models in protein structure databases
In: Protein Engineering Design and Selection [17], 537-543 |  |
| | | Hannemann, A.
Schön, J.C.
Jansen, M.
Putz, H.
Lengauer, Thomas | | Modelling amorphous Si3B3N7: Structure and elastic properties
In: Physical Review [B 70], 144201-144201 |  |
 |  |  | Hofmann, W.P.
Herrmann, E.
Kronenberger, B.
Merkwirth, Christian
Welsch, Christoph
Lengauer, Thomas
Zeuzem, S.
Sarrazin, C. | | Association of HCV-related mixed cryoglobulinemia with specific mutational patterns of the HCV E2 protein and CD81 expression on peripheral B lymphocytes
In: Blood [104], 1228-1229 |  |
| | | James, Jackson
Das, Ani V.
Rahnenführer, Jörg
Ahmad, Iqbal | | Cellular and Molecular Characterization of Early and Late Retinal Stem Cells/Progenitors: Differential Regulation of Proliferation and Context Dependent Role of Notch Signaling
In: Journal of Neurobiology [61], 359-376 |  |
 |  |  | James, Jackson
Das, Ani V.
Zhao, Xing
Rahnenführer, Jörg
Ahmad, Iqbal | | Identification of c-Kit receptor as a regulator of adult neural stem cells in the mammalian eye: interactions with Notch signaling
In: Developmental Biology [273], 87-105 |  |
| | | Lengauer, Thomas
Lemmen, Christian
Rarey, Matthias
Zimmermann, M. | | Novel technologies for virtual screening
In: Drug Discovery Today [9], 27-34 |  |
 |  |  | Merkwirth, Christian
Mauser, H.
Schulz-Gasch, T.
Roche, O.
Stahl, M.
Lengauer, Thomas | | Ensemble methods for classification in cheminformatics
In: Journal of Chemical Information and Modeling [44], 1971-1978 |  |
| | | Öhsen von, Niklas
Sommer, Ingolf
Zimmer, Ralf
Lengauer, Thomas | | Arby: Automatic protein structure prediction using profile-profile alignment and confidence measures
In: Bioinformatics [20], 2228-2235 |  |
 |  |  | Prlic, Andreas
Domingues, Francisco S.
Lackner, Peter
Sippl, Manfred J. | | WILMA-automated annotation of protein sequences
In: Bioinformatics [20], 127-128 |  |
| | | Rahnenführer, Jörg
Bozinov, Daniel | | Hybrid clustering for microarray image analysis combining intensity and shape features
In: BMC Bioinformatics [5], 1-11 |  |
 |  |  | Sommer, Ingolf
Rahnenführer, Jörg
Domingues, Francisco S.
de Lichtenberg, Ulrik
Lengauer, Thomas | | Predicting Protein Structure Classes from Function Predictions
In: Bioinformatics [20], 770-776 |  |
| | | Stoll, Monika
Corneliussen, Brit
Costello, Christine M.
Waetzig, Georg H.
Mellgard, Bjorn
Koch, W. Andreas
Rosenstiel, Philip
Albrecht, Mario
Croucher, Peter J.P.
Seegert, Dirk
Nikolaus, Susanna
Hampe, Jochen
Lengauer, Thomas
Pierrou, Stefan
Foelsch, Ulrich R.
Mathew, Christopher G.
Lagerstrom-Fermer, Maria
Schreiber, Stefan | | Genetic variation in DLG5 is associated with inflammatory bowel disease
In: Nature Genetics [36], 376-380 |  |
1 |
|
  | Electronic Journal Article |
|  |
| | | Rahnenführer, Jörg
Domingues, Francisco S.
Maydt, Jochen
Lengauer, Thomas | | Calculating the statistical significance of changes in pathway activity from gene expression data
In: Statistical Applications in Genetics and Molecular Biology [3], Article 16 |  |
3 |
|
|  |
| | | Binsl, Thomas |  | Implementation of a Generic Fragment
Based Method for Automated
Calculation of the Octanol-Water
Partition Coefficient
Universität des Saarlandes |  |
 |  |  | Eyrisch, Susanne |  | Fun2Struc-A Tool For Predicting Protein Structure
Classes from Function Predictions
Universität des Saarlandes |  |
| | | Schlicker, Andreas |  | Automated Differential Analysis of Proteomes
Universität des Saarlandes |  |
4 |
|
|  |
| | | Bayjanov, Jumamurat | | Scoring pathway activity from gene
expression data
Universität des Saarlandes |  |
 |  |  | Ramírez, Fidel | | Hacia una comprension de la accion de la recombinacion genetica y la mutacion en el origen de la variacion fenotipica, mediante el analisis de la computacion evolutiva
Universidad Nacional de Colombia |  |
| | | Sing, Tobias | | Learning localized rule mixtures by maximizing the area under the ROC curve, with an application to the prediction of HIV-1 coreceptor usage
Universität Freiburg |  |
 |  |  | Trajkovski, Igor | | Analysis of protein binding pocket flexibility
Universität des Saarlandes |  |
1 |
|
 | Thesis - other |
|  |
 |  |  | Sander, Oliver | | Local sequence-structure relationships in proteins
Friedrich-Alexander-Universität Erlangen-Nürnberg |  |
35 |
 | 2003 |
|  |
2 |
|
|  |
| | | Beerenwinkel, Niko
Däumer, Martin
Hoffmann, Daniel
Kaiser, Rolf
Selbig, Joachim
Lengauer, Thomas | | Bioinformatikmethoden für die Optimierung antiviraler Kombinationstherapien
In: MPG Jahrbuch, 481-486 |  |
 |  |  | Lengauer, Thomas
Schäfer, M. | | Combinatorial Optimization Techniques for Three-Dimensional Arrangement Problems
In: Mathematics - Key Technology for the Future, 63-73 |  |
8 |
|
 | Proceedings Article |
|  |
 |  |  | Beerenwinkel, Niko
Däumer, Martin
Kaiser, Rolf
Walter, Hauke
Korn, Klaus
Hoffmann, Daniel
Selbig, Joachim
Lengauer, Thomas | | Estimating effective drug combinations against drug-resistant mutants from genotypes
In: Proceedings of the 1st European HIV Drug Resistamce Workshop, 18-18 |  |
| | | Beerenwinkel, Niko
Kaiser, Rolf
Rahnenführer, Jörg
Däumer, Martin
Hoffmann, Daniel
Selbig, Joachim
Lengauer, Thomas | | Tree models for the evolution of drug resistance
In: XII International HIV Drug resistance Workshop, S107-S107 |  |
 |  |  | Jose, Joachim
Betschieder, Dirk
Ray, Somak
Lengauer, Thomas
Zangen, D | | New inhibitors of human cathepsin G identified by surface display library screening and peptide-protein docking
In: 7th International Symposium on Pharmaceutical Sciences (ISOPS-7), 46-49 |  |
| | | Merkwirth, Christian
Ogorzalek, Maciej
Wichard, Jörg Daniel |  | Stochastic Gradient Descent Training of Ensembles of DT-CNN Classifiers for Digit Recognition
In: Proceedings of the 16th European Conference on Circuit Theory and Design ECCTD'03, 337-341 |  |
 |  |  | Rahnenführer, Jörg | | Efficient Clustering Methods for Tumor Classification with Microarrays
In: Proceedings of the 26th Annual Conference of the Gesellschaft für Klassifikation, 670-679 |  |
| | | Rahnenführer, Jörg | | Statistical Inference for Clustering Microarrays
In: Proceedings of the MSRI Workshop: Nonlinear Estimation and Classification, 323-332 |  |
 |  |  | Talwar, Priti
Lengauer, Thomas
Wittmann, Christoph
Mangadu, Vidya
Heinzle, Elmar | | Towards cellular function through metabolite screening
In: Proceedings of the 3rd Annual Conference on Metabolic Profiling: Pathways in Discovery, 7 |  |
| | | von Öhsen, Niklas
Sommer, Ingolf
Zimmer, Ralf | | Profile-Profile Alignment: A Powerful Tool For Protein Structure Prediction
In: Pacific Symposium on Biocomputing, PSB 2003, 252-263 |  |
3 |
|
|  |
| | | Antes, Iris
Lengauer, Thomas
Mueller, Ursula
Ulmschneider, Sarah
Hartmann, Rolf | | Docking into the homology models of CYP11B1 and CYP11B2
In: Proceedings of the German Conference on Bioinformatics 2003, 13 |  |
 |  |  | Kämper, Andreas
Lengauer, Thomas | | Virtual Screening for novel Urease Inhibitors
In: Proceedings of the International Workshop on New Approaches in Drug Design & Discovery, 39 |  |
| | | Rahnenführer, Jörg
Bozinov, Daniel | | Comparative quality analyses for hybrid clustering of microarray images
In: Proceedings of the Sventh Annual International Conference on Computational Biology, - |  |
19 |
|
|  |
| | | Albrecht, Mario
Domingues, Francisco S.
Schreiber, Stefan
Lengauer, Thomas | | Identification of mammalian orthologs associates PYPAF5 with distinct functional roles
In: FEBS Letters [538], 173-177 |  |
 |  |  | Albrecht, Mario
Domingues, Francisco S.
Schreiber, Stefan
Lengauer, Thomas | | Structural localization of disease-associated sequence variations in the NACHT and LRR domains of PYPAF1 and NOD2
In: FEBS Letters [554], 520-528 |  |
| | | Albrecht, Mario
Hoffmann, Daniel
Evert, Bernd O.
Schmitt, Ina
Wüllner, Ullrich
Lengauer, Thomas | | Structural modeling of ataxin-3 reveals distant homology to adaptins
In: Proteins: Structure, Function, and Genetics [50], 355-370 |  |
 |  |  | Albrecht, Mario
Lengauer, Thomas | | Pyranose oxidase identified as a member of the GMC oxidoreductase family
In: Bioinformatics [19], 1216-1220 |  |
| | | Albrecht, Mario
Lengauer, Thomas
Schreiber, Stefan | | Disease-associated variants in PYPAF1 and NOD2 result in similar alterations of conserved sequence
In: Bioinformatics [19], 2171-2175 |  |
 |  |  | Albrecht, Mario
Tosatto, Silvio C.E.
Lengauer, Thomas
Valle, Giorgio | | Simple consensus procedures are effective and sufficient in secondary structure prediction
In: Protein Engineering [16], 459-462 |  |
| | | Antes, Iris
Wang, Hongyun
Chandler, David
Oster, George | | The unbinding of ATP from F1-ATPase
In: Biophysical Journal [85], 695-706 |  |
 |  |  | Beerenwinkel, Niko
Däumer, Martin
Oette, Mark
Korn, Klaus
Hoffmann, Daniel
Kaiser, Rolf
Lengauer, Thomas
Selbig, Joachim
Walter, Hauke | | Geno2pheno: estimating phenotypic drug resistance from HIV-1 genotypes
In: Nucleic Acids Research [31], 3850-3855 |  |
| | | Beerenwinkel, Niko
Lengauer, Thomas
Däumer, Martin
Kaiser, Rolf
Walter, Hauke
Korn, Klaus
Hoffmann, Daniel
Selbig, Joachim | | Methods for optimizing antiviral combination therapies
In: Bioinformatics [19], i16-i25 |  |
 |  |  | Domingues, Francisco S.
Lengauer, Thomas | | Protein Function from Sequence and Structure Data
In: Applied Bioinformatics [2], 3-12 |  |
| | | Janssen, A.
Rahnenführer, Jörg | | A hazard based approach to dependence tests for bivariate censored models
In: Mathematical Methods in Statistics [11], 297-322 |  |
 |  |  | Lengauer, Thomas | | Analyzing resistance phenomena in HIV with bioinformatics methods
In: Bioinformatics [19], 92i |  |
| | | Olsen, Lars
Antony, Jens
Ryde, Ulf
Adolph, Hans-Werner
Hemmingsen, Lars | | Lactam hydrolysis catalyzed by mononuclear metallo-beta-lactamases: a density functional study
In: Journal of Physical Chemistry / B [107], 2366-2375 |  |
 |  |  | Peinado, M.
Lengauer, Thomas | | Parallel "go with the winners algorithms" in Distributed Memory Models
In: Journal of Parallel and Distributed Processing [63], 801-814 |  |
| | | Rahnenführer, Jörg | | On preferences of general two-sided tests with applications to Kolmogorov-Smirnov-type tests
In: Statistics & Decisions [21], 115-136 |  |
 |  |  | Rahnenführer, Jörg
Futschik, Andreas | | Cost-effective screening for differentially expressed genes in microarray experiments based on normal mixtures
In: Austrian Journal of Statistics [32], 225-238 |  |
| | | Talwar, Priti
Wittmann, Christoph
Lengauer, Thomas
Heinzle, Elmar | | Software tool for automated processing of 13C labeling data from mass spectrometry data
In: BioTechniques [35], 1214-1215 |  |
 |  |  | Wolf, Katharina
Walter, Hauke
Beerenwinkel, Niko
Keulen, Wilco
Kaiser, Rolf
Hoffmann, Daniel
Lengauer, Thomas
Selbig, Joachim
Vandamme, Anne-Mieke
Korn, Klaus
Schmidt, Barbara | | Tenofovir resistance and resensitization
In: Antimicrobial Agents and Chemotherapy [47], 3478-3484 |  |
| | | Zien, Alexander
Fluck, Juliane
Zimmer, Ralf
Lengauer, Thomas | | Microarrays: How many do you need?
In: Journal of Computational Biology [10], 653-667 |  |
1 |
|
|  |
| | | Beerenwinkel, Niko |  | Computational Analysis of HIV Drug Resistance Data
Universität des Saarlandes |  |
1 |
|
|  |
| | | Kämper, Andreas
Lengauer, Thomas | | ECLIPPSE: Environment for Chemical Library Inspection, Pre- and Postprocessing, and Screening Evaluation. User Guide |  |
1 |
|
|  |
| | | James, Jackson
Das, Ani V.
Rahnenführer, Jörg
Leon, FAS
Ahmad, Iqbal | | Identification of rat brahma (rBRM), a subunit of SWI/SNF chromatin remodeling complex: Involvement in the differentiation of retinal stem cells/progenitors |  |
28 |
|  |
1 |
|
 | Proceedings |
|  |
 |  |  | Lengauer, Lenhof (ed.) | | Proceedings of the European Conference on Computational Biology (ECCB 2002) |  |
8 |
|
 | Proceedings Article |
|  |
 |  |  | Beerenwinkel, Niko
Lengauer, Thomas
Däumer, Martin
Sierra, S.
Schmidt, Barbara
Walter, Hauke
Korn, Klaus
Oette, Mark
Fätkenheuer, Gerd
Rockstroh, J.
Hoffmann, Daniel
Kaiser, Rolf
Selbig, Joachim | | Geno2pheno is predictive of short-term virological response
In: Proceedings from the 5th International Workshop on HIV Drug Resistance & Treatment Strategies, 74-74 |  |
| | | Beerenwinkel, Niko
Lengauer, Thomas
Schmidt, Barbara
Walter, Hauke
Kaiser, Rolf
Hoffmann, Daniel
Korn, Klaus
Selbig, Joachim | | Quantitative phenotype prediction by support vector machines
In: Proceedings from the 5th International Workshop on HIV Drug resistance & Treatment Strategies, 97 |  |
 |  |  | Bozinov, Daniel
Rahnenführer, Jörg
Burson, Cathy
Spiegelstein, Ofer | | Automated Grid Alignment for High-Throughput Analysis of Microarray Images (CIIST-02)
In: Proceedings of the 2002 International Conference on Imaging Science, Systems, and Technology, 161-167 |  |
| | | Hanisch, Daniel
Zien, Alexander
Zimmer, Ralf
Lengauer, Thomas | | Co-clustering of biological networks and gene expression data
In: Proceedings of the Tenth Conference on Intelligent Systems for Molecular Biology (ISMB 2002), 145-154 |  |
 |  |  | Hoffmann, Daniel
Schnaible, Volker
Wefing, Stephan,
Albrecht, Mario
Hanisch, Daniel
Zimmer, Ralf | | A new method for the fast solution of protein-3D-structures, combining experiments and bioinformatics
In: Coupling of Biological and Electronic Systems: Proceedings of the 2nd Caesarium, Bonn, 1-3 November 2000, 59-78 |  |
| | | Lienhart, Rainer
Maydt, Jochen | | An Extended Set of Haar-like Features for Rapid Object Detection
In: Proceedings of the International Conference on Image Processing, 900-903 |  |
 |  |  | Maydt, Jochen
Lienhart, Rainer | | A Fast Method for Training Support Vector Machines With a Very Large Set of Linear Features
In: Proceedings of the International Conference on Multimedia and Expo, 309-312 |  |
| | | Zien, Alexander
Fluck, Juliane
Zimmer, Ralf
Lengauer, Thomas | | Microarrays: How Many Do You Need?
In: Proceedings of the Sixth Annual Conference on Research in Computational Molecular Biology (RECOMB2002), 321-330 |  |
5 |
|
|  |
| | | Antes, Iris
Chandler, David
Oster, George | | A classical dynamics study of the unbinding of ATP from the F0F1-ATPase
In: Poster book of the European Conference on Computational Biology, Saarbrücken, Germany 2002, - |  |
 |  |  | Hahn, Andreas
Costello, Christine M.
Lu, Tim
Lengauer, Thomas
Schreiber, Stefan |  | Expression analysis for inflammatory bowel disease
In: Proceedings of the n?th Conference on, ? |  |
| | | Kämper, Andreas
Apostolakis, Joannis
Lengauer, Thomas | | Docking of Bacterial Cell-Wall Fragments into Glycopeptide Antibiotics
In: From Genes to Drugs via Crystallography: 33rd crytallographic course at the E. Majorana Center, 49 |  |
 |  |  | Kämper, Andreas
Lengauer, Thomas | | Docking of Ligands into Molecular Tweezers and Molecular Clips
In: Workshop of the SFB 624 'Templates', ?-? |  |
| | | Rahnenführer, Jörg | | Hybrid clustering for microarray analysis combining intensity and shape features
In: Poster book of the European Conference on Computational Biology, Saarbrücken, Germany 2002, - |  |
14 |
|
|  |
| | | Albrecht, Mario
Hanisch, Daniel
Zimmer, Ralf
Lengauer, Thomas |  | Improving fold recognition of protein threading by experimental distance constraints
In: In Silico Biology [2], 325-337 |  |
 |  |  | Antes, Iris
Thiel, Walter
Gunsteren van, Wilfred F. | | Molecular dynamics simulations of photoactive yellow protein (PYP) in three states of its photocycle: a comparison with X-ray and NMR data and analysis of the effects of Glu46 deprotonation and mutation
In: European Biophysics Jounal [31], 504-520 |  |
| | | Beerenwinkel, Niko
Schmidt, Barbara
Walter, Hauke
Kaiser, Rolf
Lengauer, Thomas
Hoffmann, Daniel
Korn, Klaus
Selbig, Joachim | | Diversity and complexity of HIV-1drug resistance: A bioinformatics approach to predicting phenotype from genotype
In: Proceedings of the National Academy of Sciences [99], 8271-8276 |  |
 |  |  | Freudenberg, Jan
Zimmer, Ralf
Hanisch, Daniel
Lengauer, Thomas | | A hypergraph-based method for unification of existing protein structure- and sequence-families
In: In Silico Biology [2], 339 - 349 |  |
| | | Hanisch, Daniel
Zimmer, Ralf
Lengauer, Thomas | | ProML - the Protein Markup Language for specification of protein sequences, structures and families
In: In Silico Biology [2], 313 - 324 |  |
 |  |  | Hindle, Sally A.
Rarey, Matthias
Buning, Christian
Lengauer, Thomas | | Flexible docking under pharmacophore type constraints
In: Journal of Computer-Aided Molecular Design [16], 129-149 |  |
| | | Lengauer, Thomas | | Ausbildung im Bereich Bioinformatik
In: Ernst & Young Report Biotechnologie, Segmentreport Bioinformatik [1], 57-58 |  |
 |  |  | Lengauer, Thomas | | Preface: Special RECOMB 2001 Issue
In: Journal of Computational Biology [9], 147-148 |  |
| | | Nishida, Yoshiharu
Hirano, Kenichi
Tsukamoto, Kosuke
Nagano, Makoto
Ikegami, Chiaki
Roomp, Kirsten
Ishihara, Mitsuaki
Sakane, Naoki
Zhang, Zhongyan
Tsujii, Ken-ichi
Matsuyama, Akifumi
Ohama, Tohru
Matsuura, Fumihiko
Ishigami, Masato
Sakai, Naohiko
Hiraoka, Hisatoyo
Hattori, Hiroaki
Wellington, Cheryl L.
Yoshida, Yoshihide
Misugi, Susumu
Hayden, Michael R.
Egashira, Toru
Yamashita, Shizuya
Matsuzawa, Yuji | | Expression and Functional Analyses of Novel Mutations ot ATP-Binding Cassette Transporter-1 in Japanese Patients with High-Density Lipoprotein Deficiency
In: Biochemical and Biophysical Research Communications [290], 713-721 |  |
 |  |  | Rahnenführer, Jörg | | Multivariate permutation tests for the k-sample problem with clustered data
In: Computational Statistics [17], 165-184 |  |
| | | Rahnenführer, Jörg
Bozinov, Daniel | | Unsupervised technique for robust target separation and analysis of DNA microarray spots through adaptive pixel clustering
In: Bioinformatics [18], 747-756 |  |
 |  |  | Sommer, Ingolf
Zien, Alexander
Öhsen von, Niklas
Zimmer, Ralf
Lengauer, Thomas | | Confidence measures for protein fold recognition
In: Bioinformatics [18], 802-812 |  |
| | | Wellington, Cheryl L.
Yang, Yu-Zhou
Zhou, Stephen
Clee, Susanne M.
Tan, Bing
Hirano, Kenichi
Zwarts, K.Y.
Kwok, Anita
Gelfer, Allison
Marcil, Michel
Newman, Scott
Roomp, Kirsten
Singaraja, Roshni
Collins, Jennifer A.
Zhang, Lin-Hua
Groen, Albert K.
Hovingh, Kees
Brownlie, Alison
Tafuri, Sherrie
Genest, Jacques Jr
Kastelein, J.J.P.
Hayden, Michael R. | | Truncation mutations in ABCA1 suppress normal upregulation of full-length ABCA1 by 9-cis-retinoic acid and 22-R-hydroxycholesterol
In: Journal of Lipid Research [43], 1939-1949 |  |
 |  |  | Zwarts, K.Y.
Clee, Susanne M.
Zwinderman, A.H.
Engert, J.C.
Singaraja, Roshni
Loubser, O
James, E
Roomp, Kirsten
Hudson, T.J.
Jukema, J.W.
Kastelein, J.J.P.
Hayden, Michael R. | | ABCA1 regulatory variants influence coronary artery disease independent of effects on plasma lipid levels
In: Clinical Genetics [61], 115-125 |  |
14 |
 | 2001 |
|  |
2 |
|
|  |
| | | Lengauer (ed.) | | From Genomes to Drugs |  |
 |  |  | Lengauer, Sankoff, Istrail, Pevzner, Waterman (ed.) | | Proceedings of the 5th Annual Conference on Research in Computational Molecular Biology (RECOMB2001) |  |
1 |
|
 | Part of a Book |
|  |
 |  |  | Lengauer, Thomas | | Bioinformatik an der Schwelle zur postgenomischen Ära
In: Was wissen wir, wenn wir das menschliche Genom kennen, 56-62 |  |
1 |
|
 | Proceedings Article |
|  |
 |  |  | Kämper, Andreas
Apostolakis, Joannis
Rarey, Matthias
Marian, Christel Maria
Lengauer, Thomas | | Docking of Ligands into Artificial Receptors
In: Electronically Excited Molecules: Structure and Dynamics, 37th Symposium for Theoretical Chemistry, P76 |  |
8 |
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 | Journal Article |
|  |
 |  |  | Apostolakis, Joannis
Hofmann, D.
Lengauer, Thomas | | Derivation of a scoring function for crystal structure prediction
In: Acta Crystallographica [A57], 442-450 |  |
| | | Beerenwinkel, Niko
Däumer, Martin
Hoffmann, Daniel
Kaiser, Rolf
Korn, Klaus
Lengauer, Thomas
Schmidt, Barbara
Walter, Hauke
Selbig, Joachim | | Neue Wege zur Optimierung von Anti-HIV Therapien
In: BIOforum [24], 912-914 |  |
 |  |  | Beerenwinkel, Niko
Schmidt, Barbara
Walter, Hauke
Kaiser, Rolf
Lengauer, Thomas
Hoffmann, Daniel
Korn, Klaus
Selbig, Joachim | | Geno2pheno: A system for the interpretation of genotypic HIV Drug resistance tests
In: IEEE Intelligent Systems [16], 35-41 |  |
| | | Claussen, C.
Buning, Christian
Rarey, Matthias
Lengauer, Thomas | | FlexE: Efficient Molecular Docking Considering Protein Structure Variations
In: Journal of Molecular Biology [308], 377-395 |  |
 |  |  | Clee, Susanne M.
Zwinderman, A.H.
Engert, J.C.
Zwarts, K.Y.
Molhuizen, H.O.
Roomp, Kirsten
Jukema, J.W.
van Wijland, M
van Dam, M
Hudson, T.J.
Brooks-Wilson, A
Genest, Jacques Jr
Kastelein, J.J.P.
Hayden, Michael R. | | Common genetic variation in ABCA1 is associated with altered lipoprotein levels and a modified risk for coronary artery disease
In: Circulation [103], 1198-205 |  |
| | | Lengauer, Thomas
Beerenwinkel, Niko
Schmidt, B.
Walter, H.
Kaiser, R.
Hoffmann, D.
Korn, K.
Selbig, J. | | Geno2pheno: a new machine learning approach to predicting phenotypic drug resistance from genotype
In: Antiviral Therapy [6], 104 |  |
 |  |  | Schäfer, M.
Lengauer, Thomas | | Automated Layout Generation and Wiring Area Estimation for 3D Electronic Modules
In: ASME Journal of Machanical Design [123], 330-336 |  |
| | | Zien, Alexander
Aigner, T.
Zimmer, Ralf
Lengauer, Thomas | | Centralization: A biologically sensible method for the normalization of gene expression data
In: Bioinformatics [17], 323S-331S |  |
2 |
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Klein, Michael L. | | The formation of a β-Peptide/DPC-micelle complex studied by MD simulations |  |
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Apostolakis, Joannis
Rarey, Matthias
Marian, Christel Maria
Lengauer, Thomas | | Docking of Ligands into Artificial Receptors |  |
2 |
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2 |
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Kastelein, J.J.P.
van Dam, M
Marcil, Michel
Roomp, Kirsten
Zwarts, K.Y.
Collins, Jennifer A.
Roelants, R
Tamasawa, N
Stulc, T
Suda, T
Ceska, R
Boucher, B
Rondeau, C
DeSouich, C
Brooks-Wilson, A
Molhuizen, H.O.
Frohlich, J
Genest, Jacques Jr
Hayden, Michael R. | | Age and residual cholesterol efflux affect HDL cholesterol levels and coronary artery disease in ABCA1 heterozygotes
In: Journal of Clinical Investigation [106], 1263-70 |  |
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Garcia, Sergio | | GenLab: Laboratorio virtual de genetica
In: Acta Biologica Colombiana [5], 45-48 |  |
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Molhuizen, H.O.
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Fichter, K
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Scherer, S
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Martindale, D
Frohlich, J
Morgan, K
Koop, B
Pimstone, S
Kastelein, J.J.P.
Hayden, Michael R. | | Mutations in ABC1 in Tangier disease and familial high-density lipoprotein
In: Nature Genetics [22], 336-45 |  |
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Brooks-Wilson, A.
Clee, Susanne M.
Roomp, Kirsten
Zhang, Lin-Hua
Yu, L.
Collins, Jennifer A.
van Dam, M.
Molhuizen, H. O.
Loubser, O.
Ouelette, B. F.
Sensen, C. W.
Fichter, K.
Mott, S.
Denis, M.
Boucher, B.
Pimstone, S.
Genest, Jacques
Kastelein, J. J. P.
Hayden, Michael R. | | Mutations in the ABC1 gene in familial HDL deficiency with defective cholesterol efflux
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