Your search returned the following 32 documents:
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Efficacy of antiretroviral therapy switch in HIV-infected patients: A 10-year analysis of the EuResist cohort
Mark Oette, Eugen Schulter, Michal Rosen-Zvi, Yardena Peres, Maurizio Zazzi, Anders Sonnerborg, Daniel Struck, Andre Altmann, and Rolf Kaiser
Intervirology 55 (2): 160-166, 2012
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Predicting Response to Antiretroviral Treatment by Machine Learning:
The EuResist Project
Maurizio Zazzi, Francesca Incardona, Michal Rosen-Zvi, Mattia Prosperi, Thomas Lengauer, Andre Altmann, Anders Sonnerborg, Tamar Lavee, Eugen Schülter, and Rolf Kaiser
Intervirology 55 (2): 123-127, 2012
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A Computational Method for Predicting First-Line Antiretroviral Therapy Success
Alejandro Pironti, André Altmann, Joachim Büch, and Thomas Lengauer
In: Abstract Book. 9th Workshop on HIV & Hepatitis Treatment Strategies & Antiviral Drug Resistance, Paphos, Cyprus, 2011, 94 p.
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Learning from past treatments and their outcome improves prediction of In Vivo response to anti-HIV therapy
Hiroto Saigo, André Altmann, Jasmina Bogojeska, Fabian Müller, Sebastian Nowozin, and Thomas Lengauer
Statistical Applications in Genetics and Molecular Biology 10 (1): 1-32, 2011
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Prediction of Response to Antiretroviral Therapy by Human Experts and by the EuResist Data-Driven Expert System (the EVE study)
M. Zazzi, R. Kaiser, A. Sönnerborg, D Struck, Andre Altmann, M. Prosperi, M. Rosen-Zvi, A. Petroczi, Y. Peres, E. Schülter, C.A. Boucher, F. Brun-Vezinet, R. Harrigan, L. Morris, M. Obermeier, C.-F. Perno, P. Phanuphak, D Pillay, R.W. Shafer, A.-M. Vandamme, K. Van Laethem, A. Wensing, Thomas Lengauer, and F. Incardona
HIV Medicine 12 (4): 211-218, 2011
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HIV-1 mutational pathways under multidrug therapy
Glenn Lawyer, André Altmann, Alex Thielen, Maurizio Zazzi, Anders Sönnerborg, and Thomas Lengauer
AIDS Research and Therapy 8 (1): 1-13, 2011
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Antiretroviral Therapy Optimisation without Genotype Resistance Testing: A Perspective on Treatment History Based Models
Mattia C. F. Prosperi, Michal Rosen-Zvi, Andre Altmann, Maurizio Zazzi, Simona Di Giambenedetto, Rolf Kaiser, Eugen Schülter, Daniel Struck, Peter Sloot, David A. van de Vijver, Anne-Mieke Vandamme, and Anders Sönnerborg
PLoS ONE 5 (10): e13753,1-e13753,8, 2010
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Bioinformatical approaches to ranking of anti-HIV combination therapies and planning of treatment schedules
André Altmann
Doctoral dissertation, Universität des Saarlandes, 2010
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Chasing the AIDS Virus
Thomas Lengauer, André Altmann, Alexander Thielen, and Rolf Kaiser
Communications of the ACM 53 (3): 66-74, 2010
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Dealing with sparse data in predicting outcomes of HIV combination therapies
Jasmina Bogojeska, Steffen Bickel, André Altmann, and Thomas Lengauer
Bioinformatics 26 (17): 2085-2092, 2010
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Determination of clinically relevant cutoffs for HIV-1 phenotypic resistance estimates through a combined analysis of clinical trial and cohort data
Andre Altmann, Alejandro Pironti, Juliane Perner, Joachim Büch, and Thomas Lengauer
In: Abstract Book. 8th European Drug Resistance Workshop, Sorrento, Italy, 2010, 46 p.
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Only Slight Impact of Predicted Replicative Capacity for Therapy Response Prediction
Hendrik Weisser, André Altmann, Saleta Sierra, Francesca Incardona, Daniel Struck, Anders Sönnerborg, Rolf Kaiser, Maurizio Zazzi, Monika Tschochner, Hauke Walter, and Thomas Lengauer
PLoSOne 5 (2): e9044,1-e9044,10, 2010
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Permutation importance: an unbiased feature importance measure
André Altmann, Laura Tolosi, Oliver Sander, and Thomas Lengauer
Bioinformatics 26 (10): 1340-1347, 2010
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Prediction of Response to Antiretroviral Therapy by Human Experts and by the EuResist Data-Driven Expert System (the EVE Study)
Maurizio Zazzi, Rolf Kaiser, Anders Sönnerborg, Daniel Struck, Andre Altmann, Mattia C. F. Prosperi, Michal Rosen-Zvi, Andrea Petroczi, Yardena Peres, Eugen Schülter, Charles Boucher, Francoise Brun-Vezinet, Richard Harigan, Lynn Morris, Martin Obermeier, Federico Perno, Robert Shafer, Anne-Mieke Vandamme, Kristel van Laethem, Annemarie Wensing, Thomas Lengauer, and Francesca Incardona
HIV Medicine Early View: 1-8, 2010
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Advantages of Predicted Phenotypes and Statistical Learning Models in Inferring Virological Response to Antiretroviral Therapy from HIV Genotype
André Altmann, Tobias Sing, Hans Vermeiren, Bart Winters, Elke Van Craenenbroeck, Koen Van der Borght, Soo-Yon Rhee, Robert W. Shafer, Eugen Schülter, Rolf Kaiser, Yardena Peres, Anders Sönnerborg, W. Jeffrey Fessel, Francesca Incardona, Maurizio Zazzi, Lee Bacheler, Hermann Van Vlijmen, and Thomas Lengauer
Antiviral Therapy 14 (2): 273-283, 2009
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Bioinformatische Unterstützung der Auswahl von HIV Therapien
Thomas Lengauer, André Altmann, and Alexander Thielen
Informatik Spektrum 32 (2): 320-331, 2009
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Estimating evolutionary pathways to 7CXCR4 usage from cross-sectional data
Alexander Thielen, André Altmann, Jasmina Bogojeska, Rolf Kaiser, and Thomas Lengauer
In: Abstracts presented at the XVIII International HIV Drug Resistance Workshop : Basic Principles & Clinical Implications, Fort Myers, USA, 2009, A16-A16, paper no. Abstract 14.
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Evolution of raltegravir resistance during therapy
Nadine Sichtig, Saleta Sierra, Rolf Kaiser, Martin Däumer, Stefan Reuter, Eugen Schülter, André Altmann, Gerd Fätkenheuer, Ulf Dittmer, Herbert Pfister, and Stefan Esser
Journal of antimicrobial chemotherapy 64 (1): 25-32, 2009
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Investigation of expert rule bases, logistic regression, and non-linear machine learning techniques for predicting response to antiretroviral treatment
Mattia C. F. Prosperi, André Altmann, Michal Rosen-Zvi, Ehud Aharoni, Borgulya Gabor, Bazso Fulop, Anders Sonnerborg, Eugen Schulter, Daniel Struck, Giovanni Ulivi, Anne-Mieke Vandamme, Jurgen Vercauteren, and Maurizio Zazzi
Antiviral Therapy 14 (3): 433-442, 2009
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Predicting the Response to Combination Antiretroviral Therapy: Retrospective Validation of
geno2pheno-THEO on a Large Clinical Database
André Altmann, Martin Däumer, Niko Beerenwinkel, Yardena Peres, Eugen Schülter, Joachim Büch, Soo-Yon Rhee, Anders Sönnerborg, W. Jeffrey Fessel, Robert W. Shafer, Maurizio Zazzi, Rolf Kaiser, and Thomas Lengauer
The Journal of Infectious Diseases 199 (7): 999-1006, 2009
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Comparison of Classifier Fusion Methods for Predicting Response to Anti HIV-1 Therapy
Andre Altmann, Michal Rosen-Zvi, Mattia Prosperi, Ehud Aharoni, Hani Neuvirth, Anders Sönnerborg, Eugen Schülter, Joachim Büch, Daniel Struck, Yardena Peres, Francesca Incardona, Rolf Kaiser, Maurizio Zazzi, and Thomas Lengauer
PLoS ONE 3 (10): e3470 p., 2008
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Computational analysis of covariation and interactions between HIV-1 reverse transcriptase and Integrase
Oliver Sander, Andre Altmann, and Thomas Lengauer
In: Reviews in Antiviral Therapy, Budapest, Hungary, 2008, 113-114
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Improved genotypic prediction of HIV-1 coreceptor usage by incorporating V2 loop sequence variation
Alexander Thielen, P Richard Harrigan, Andrew J. Low, A Moores, Andre Altmann, Kasia Bozek, Eva Heger, Nadine Sichtig, Rolf Kaiser, and Thomas Lengauer
In: Antiviral Therapy, Sitges, Spain, 2008, A100 p.
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Relevance of HIV gag cleavage site mutations in failures of protease inhibitor therapies
Jens Verheyen, Andre Altmann, Elena Knops, Eugen Schülter, Nadine Sichtig, Stefan Reuter, Gerd Fätkenheuer, Herbert Pfister, and Rolf Kaiser
In: Antiviral Therapy, Sitges, Spain, 2008, A53 p.
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Rtreemix: an R package for estimating evolutionary pathways and genetic progression scores
Jasmina Bogojeska, Adrian Alexa, André Altmann, Thomas Lengauer, and Jörg Rahnenführer
Bioinformatics 24 (20): 2391-2392, 2008
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Selecting anti-HIV therapies based on a variety of genomic and clinical factors
Michal Rosen-Zvi, Andre Altmann, Mattia Prosperi, Ehud Aharoni, Hani Neuvirth, Anders Sönnerborg, Eugen Schülter, Daniel Struck, Yardena Peres, Francesca Incardona, Rolf Kaiser, Maurizio Zazzi, and Thomas Lengauer
In: Proceedings of the 16th Annual International Conference on Intelligent Systems for Molecular Biology (ISMB 2008), Toronto, Canada, 2008, i399-406
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Sustaining lamivudine/emtricitabine, abacavir, zidovudine or atazanavir from a previous treatment shows a clinical benefit
Michal Rosen-Zvi, Eugen Schülter, Andre Altmann, Saleta Sierra-Aragon, Maurizio Zazzi, Anders Sönnerborg, Mark Oette, Thomas Lengauer, and Rolf Kaiser
In: Antiviral Therapy, Sitges, Spain, 2008, A86 p.
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The EuResist approach for predicting response to anti HIV-1 therapy
Andre Altmann, Michal Rosen-Zvi, Mattia Prosperi, Ehud Aharoni, Hani Neuvirth, Eugen Schülter, Joachim Büch, Yardena Peres, Incardona Incardona, Anders Sönnerborg, Rolf Kaiser, Maurizio Zazzi, and Thomas Lengauer
In: Reviews in Antiviral Therapy, Budapest, Hungary, 2008, 107 p.
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Improved prediction of response to antiretroviral combination therapy using the genetic barrier to drug resistance
Andre Altmann, Niko Beerenwinkel, Tobias Sing, Igor Savenkov, Martin Däumer, Rolf Kaiser, Soo-Yon Rhee, W Jeffrey Fessel, Robert W Shafer, and Thomas Lengauer
Antiviral Therapy 12 (2): 169-178, 2007
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Inferring virological response from genotype: with or without predicted phenotypes?
Andre Altmann, Tobias Sing, Hans Vermeiren, Bart Winters, Elke Van Craenenbroeck, Koen Van der Borght, Soo-Yon Rhee, Robert W Shafer, Eugen Schülter, Rolf Kaiser, Yardena Peres, Anders Sonnerborg, W Jeffrey Fessel, Francesca Incardona, Maurizio Zazzi, Lee Bacheler, Hermann Van Vlijmen, and Thomas Lengauer
In: Proceedings of the 16th International HIV Drug Resistance Workshop, Barbados, Barbados, 2007, S169 p.
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Validation of geno2pheno and THEO on a large independent clinical dataset
Andre Altmann, Martin Däumer, Tobias Sing, Niko Beerenwinkel, Hauke Walter, Rolf Kaiser, and Thomas Lengauer
In: Proceedings of the 5th European HIV Drug Resistance Workshop, Cascais, Portugal, 2007
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EuResist: exploration of multiple modeling techniques for prediction of response to treatment
Maurizio Zazzi, Ehud Aharoni, Andre Altmann, Fulop Baszó, Penny Bidgood, Gabór Borgulya, J Denholm-Prince, M Fielder, Rolf Kaiser, Carmel Kent, Thomas Lengauer, T Nepusz, Hanni Neuvirth, Yardena Peres, Andrea Petroczi, Mattia Prosperi, L Romano, Michal Rosen-Zvi, Eugen Schülter, Tobias Sing, Andras Sonnerborg, R Thompson, G Ulivi, L Zalány, and Francesca Incardona
In: Proceedings of the 5th European HIV Drug Resistance Workshop, Cascais, Portugal, 2007