Your search returned the following 90 documents:
-
Association between variants of PRDM1 and NDP52 and Crohn's disease, based on exome sequencing and functional studies
David Ellinghaus, Hu Zhang, Sebastian Zeissig, Simone Lipinski, Andreas Till, Tao Jiang, Björn Stade, Yana Bromberg, Eva Ellinghaus, Andreas Keller, Manuel A. Rivas, Jurgita Skieceviciene, Nadezhda T. Doncheva, Xiao Liu, Qing Liu, Fuman Jiang, Michael Forster, Gabriele Mayr, Mario Albrecht, Robert Häsler, Bernhard O. Boehm, Jane Goodall, Carlo R. Berzuini, James Lee, Vibeke Andersen, Ulla Vogel, Limas Kupcinskas, Manfred Kayser, Michael Krawczak, Susanna Nikolaus, Rinse K. Weersma, Cyriel Y. Ponsioen, Miquel Sans, Cisca Wijmenga, David P. Strachan, Wendy L. McArdle, Séverine Vermeire, Paul Rutgeerts, Jeremy D. Sanderson, Christopher G. Mathew, Morten H. Vatn, Jun Wang, Markus M. Nöthen, Richard H. Duerr, Carsten Büning, Stephan Brand, Jürgen Glas, Juliane Winkelmann, Thomas Illig, Anna Latiano, Vito Annese, Jonas Halfvarson, Mauro D'Amato, Mark J. Daly, Michael Nothnagel, Tom H. Karlsen, Suresh Subramani, Philip Rosenstiel, Stefan Schreiber, Miles Parkes, and Andre Franke
Gastroenterology 145 (2): 339-347, 2013
-
Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis
Jimmy Z. Liu, Johannes Roksund Hov, Trine Folseraas, Eva Ellinghaus, Simon M. Rushbrook, Nadezhda T. Doncheva, Ole A. Andreassen, Rinse K. Weersma, Tobias J. Weismuller, Bertus Eksteen, Pietro Invernizzi, Gideon M. Hirschfield, Daniel Nils Gotthardt, Albert Pares, David Ellinghaus, Tejas Shah, Brian D. Juran, Piotr Milkiewicz, Christian Rust, Christoph Schramm, Tobias Muller, Brijesh Srivastava, Georgios Dalekos, Markus M. Nothen, Stefan Herms, Juliane Winkelmann, Mitja Mitrovic, Felix Braun, Cyriel Y. Ponsioen, Peter J. P. Croucher, Martina Sterneck, Andreas Teufel, Andrew L. Mason, Janna Saarela, Virpi Leppa, Ruslan Dorfman, Domenico Alvaro, Annarosa Floreani, Suna Onengut-Gumuscu, Stephen S. Rich, Wesley K. Thompson, Andrew J. Schork, Sigrid Naess, Ingo Thomsen, Gabriele Mayr, Inke R. Konig, Kristian Hveem, Isabelle Cleynen, Javier Gutierrez-Achury, Isis Ricano-Ponce, David van Heel, Einar Bjornsson, Richard N. Sandford, Peter R. Durie, Espen Melum, Morten H. Vatn, Mark S. Silverberg, Richard H. Duerr, Leonid Padyukov, Stephan Brand, Miquel Sans, Vito Annese, Jean-Paul Achkar, Kirsten Muri Boberg, Hanns-Ulrich Marschall, Olivier Chazouilleres, Christopher L. Bowlus, Cisca Wijmenga, Erik Schrumpf, Severine Vermeire, Mario Albrecht, The UK-PSCSC Consortium, The International IBD Genetics Consortium, John D. Rioux, Graeme Alexander, Annika Bergquist, Judy Cho, Stefan Schreiber, Michael P. Manns, Martti Farkkila, Anders M. Dale, Roger W. Chapman, Konstantinos N. Lazaridis, The International PSC Study Group, Andre Franke, Carl A. Anderson, and Tom H. Karlsen
Nature Genetics 45 (6): 670-677, 2013
-
NetworkPrioritizer: a versatile tool for network-based prioritization of candidate disease genes or other molecules
Tim Kacprowski, Nadezhda T. Doncheva, and Mario Albrecht
Bioinformatics 29 (11): 1471-1473, 2013
[PDF: Download: Bioinformatics-2013-Kacprowski-1471-3.pdf]
-
Profiling of parkin-binding partners using tandem affinity purification
Alessandra Zanon, Aleksandar Rakovic, Hagen Blankenburg, Nadezhda T. Doncheva, Christine Schwienbacher, Alice Serafin, Adrian Alexa, Christian X. Weichenberger, Mario Albrecht, Christine Klein, Andrew A. Hicks, Peter P. Pramstaller, Francisco S. Domingues, and Irene Pichler
PLoS ONE 8 (11): 1-17, 2013
-
Computational Biology
Thomas Lengauer, Mario Albrecht, and Francisco S. Domingues
In: Encyclopedia of Molecular Cell Biology and Molecular Medicine, 2012, 1-71
-
Functional characterization of human genes from exon expression and RNA interference results
Dorothea Emig, Hagen Blankenburg, Fidel Ramírez, and Mario Albrecht
In: Bioinformatics and Drug Discovery, 2012, 33-53
-
Mining GO annotations for improving annotation consistency
Daniel Faria, Andreas Schlicker, Catia Pesquita, Hugo Bastos, António E N Ferreira, Mario Albrecht, and André O Falcão
PLoS ONE 7 (7): e40519,1-e40519,7, 2012
-
Novel search method for the discovery of functional relationships
Fidel Ramírez, Glenn Lawyer, and Mario Albrecht
Bioinformatics 28 (2): 269-276, 2012
-
Recent approaches to the prioritization of candidate disease genes
Nadezhda T Doncheva, Tim Kacprowski, and Mario Albrecht
Wiley Interdisciplinary Reviews: Systems Biology and Medicine 4 (5): 429-442, 2012
-
Specificity of linear motifs that bind to a common mitogen-activated protein kinase docking groove
Ágnes Garai, András Zeke, Gergo Gógl, Imre Töro, Ferenc Fördos, Hagen Blankenburg, Tünde Bárkai, János Varga, Anita Alexa, Dorothea Emig, Mario Albrecht, and Attila Reményi
Science Signaling 5 (245): ra74,1-ra74,14, 2012
-
Topological analysis and interactive visualization of biological networks and protein structures
Nadezhda T Doncheva, Yassen Assenov, Francisco S. Domingues, and Mario Albrecht
Nature Protocols 7 (4): 670-685, 2012
-
Analyzing and visualizing residue networks of protein structures
Nadezhda T. Doncheva, Karsten Klein, Francisco S. Domingues, and Mario Albrecht
Trends in Biochemical Sciences 36 (4): 179-182, 2011
-
Comprehensive cluster analysis with Transitivity Clustering
Tobias Wittkop, Dorothea Emig, Anke Truss, Mario Albrecht, Sebastian Böcker, and Jan Baumbach
Nature Protocols 6 (3): 285-295, 2011
-
Inferring physical protein contacts from large-scale purification data of protein complexes
Sven-Eric Schelhorn, Julián Mestre, Elena Zotenko, and Mario Albrecht
Molecular & Cellular Proteomics 10 (6): M110.004929,1-M110.004929,15, 2011
-
Measuring and analyzing tissue specificity of human genes and protein complexes
Dorothea Emig, Tim Kacprowski, and Mario Albrecht
EURASIP Journal on Bioinformatics and Systems Biology 2011 (1): 5,1-5,6, 2011
-
PSICQUIC and PSISCORE: accessing and scoring molecular interactions
Bruno Aranda, Hagen Blankenburg, Samuel Kerrien, Fiona S. Brinkman, Arnaud Ceol, Emilie Chautard, Jose M. Dana, Javier De Las Rivas, Marine Dumousseau, Eugenia Galeota, Anna Gaulton, Johannes Goll, Robert E. W. Hancock, Ruth Isserlin, Rafael C. Jimenez, Jules Kerssemakers, Jyoti Khadake, David J. Lynn, Magali Michaut, Gavin O'Kelly, Keiichiro Ono, Sandra Orchard, Carlos Prieto, Sabry Razick, Olga Rigina, Lukasz Salwinski, Milan Simonovic, Sameer Velankar, Andrew Winter, Guanming Wu, Gary D. Bader, Gianni Cesareni, Ian M. Donaldson, David Eisenberg, Gerard J. Kleywegt, John Overington, Sylvie Ricard-Blum, Mike Tyers, Mario Albrecht, and Henning Hermjakob
Nature Methods 8 (7): 528-529, 2011
-
Recruitment and activation of a lipid kinase by hepatitis C virus NS5A is essential for integrity of the membranous replication compartment
Simon Reiss, Ilka Rebhan, Perdita Backes, Ines Romero-Brey, Holger Erfle, Petr Matula, Lars Kaderali, Marion Poenisch, Hagen Blankenburg, Marie-Sophie Hiet, Thomas Longerich, Sarah Diehl, Fidel Ramírez, Tamas Balla, Karl Rohr, Artur Kaul, Sandra Bühler, Rainer Pepperkok, Thomas Lengauer, Mario Albrecht, Roland Eils, Peter Schirmacher, Volker Lohmann, and Ralf Bartenschlager
Cell Host & Microbe 9 (1): 32-45, 2011
-
Structure collisions between interacting proteins
Dorothea Emig, Oliver Sander, Gabriele Mayr, and Mario Albrecht
PLoS ONE 6 (6): e19581,1-e19581,7, 2011
-
Tissue-specific proteins and functional implications
Dorothea Emig and Mario Albrecht
Journal of Proteome Research 10 (4): 1893-1903, 2011
-
DIDO: a disease-determinants ontology from web sources
Victoria Nebot, Min Ye, Mario Albrecht, Jae-Hong Eom, and Gerhard Weikum
In: Proceedings of the 20th International Conference on World Wide Web (WWW 2011), Hyderabad, India, 2011, 237-240
-
Color blindness
Mario Albrecht
Nature Methods 7 (10): 775 p., 2010
-
Dimerization of the hepatitis C virus nonstructural protein 4B depends on the integrity of an aminoterminal basic leucine zipper
Martin-Walter Welker, Christoph Welsch, Aline Meyer, Iris Antes, Mario Albrecht, Nicole Forestier, Bernd Kronenberger, Thomas Lengauer, Albrecht Piiper, Stefan Zeuzem, and Christoph Sarrazin
Protein Science 19 (7): 1327-1336, 2010
-
Finding scaffold proteins in interactomes
Fidel Ramírez and Mario Albrecht
Trends in Cell Biology 20 (1): 2-4, 2010
-
Genome-wide association study for ulcerative colitis identifies risk loci at 7q22 and 22q13 (IL17REL)
Andre Franke, Tobias Balschun, Christian Sina, David Ellinghaus, Robert Häsler, Gabriele Mayr, Mario Albrecht, Michael Wittig, Eva Buchert, Susanna Nikolaus, Christian Gieger, H. Erich Wichmann, Jurgita Sventoraityte, Limas Kupcinskas, Clive M. Onnie, Maria Gazouli, Nicholas P. Anagnou, David Strachan, Wendy L. McArdle, Christopher G. Mathew, Paul Rutgeerts, Séverine Vermeire, Morten H. Vatn, Michael Krawczak, Philip Rosenstiel, Tom H. Karlsen, and Stefan Schreiber
Nature Genetics 42 (4): 292-294, 2010
-
Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2
Eva Ellinghaus, David Ellinghaus, Philip E. Stuart, Rajan P. Nair, Sophie Debrus, John V. Raelson, Majid Belouchi, Hélène Fournier, Claudia Reinhard, Jun Ding, Yun Li, Trilokraj Tejasvi, Johann Gudjonsson, Stefan W. Stoll, John J. Voorhees, Sylviane Lambert, Stephan Weidinger, Bernadette Eberlein, Manfred Kunz, Proton Rahman, Dafna D. Gladman, Christian Gieger, H. Erich Wichmann, Tom H. Karlsen, Gabriele Mayr, Mario Albrecht, Dieter Kabelitz, Ulrich Mrowietz, Gonçalo R. Abecasis, James T. Elder, Stefan Schreiber, Michael Weichenthal, and Andre Franke
Nature Genetics 42 (11): 991-995, 2010
-
Improving disease gene prioritization using the semantic similarity of Gene Ontology terms
Andreas Schlicker, Thomas Lengauer, and Mario Albrecht
Bioinformatics 26 (18): i561-i567, 2010
-
Intragenic allele pyramiding combines different specificities of wheat Pm3 resistance alleles
Susanne Brunner, Severine Hurni, Philipp Streckeisen, Gabriele Mayr, Mario Albrecht, Nabila Yahiaoui, and Beat Keller
The Plant Journal 64 (3): 433-445, 2010
-
Measuring and analyzing tissue specificity of human genes and protein complexes
Dorothea Emig, Tim Kacprowski, and Mario Albrecht
In: Seventh International Workshop on Computational Systems
Biology, WCSB 2010, Luxembourg, Luxembourg, 2010, 27-30
-
On open problems in biological network visualization
Mario Albrecht, Andreas Kerren, Karsten Klein, Oliver Kohlbacher, Petra Mutzel, Wolfgang Paul, Falk Schreiber, and Michael Wybrow
In: Graph Drawing : 17th International Symposium, GD 2009, Chicago, IL, USA, 2010, 256-267
-
Partitioning biological data with transitivity clustering
Tobias Wittkop, Dorothea Emig, Sita Lange, Sven Rahmann, Mario Albrecht, John H. Morris, Sebastian Böcker, Jens Stoye, and Jan Baumbach
Nature Methods 7 (6): 419-420, 2010
-
AltAnalyze and DomainGraph: analyzing and visualizing exon expression data
Dorothea Emig, Nathan Salomonis, Jan Baumbach, Thomas Lengauer, Bruce R. Conklin, and Mario Albrecht
Nucleic Acids Research 38 (Suppl. 2): W755-W762, 2010
-
FunSimMat update: new features for exploring functional similarity
Andreas Schlicker and Mario Albrecht
Nucleic Acids Research 38 (Database issue): D244-D248, 2010
-
Protein-protein interactions: analysis and prediction
Dmitrij Frishman, Mario Albrecht, Hagen Blankenburg, Peer Bork, Eoghan D. Harrington, Henning Hermjakob, Lars J. Jensen, David A. Juan, Thomas Lengauer, Philipp Pagel, Vincent Schachter, and Alfonso Valencia
In: Modern Genome Annotation - The Biosapiens Network, 2009, 353-410
-
DASMIweb: online integration, analysis and assessment of distributed protein interaction data
Hagen Blankenburg, Fidel Ramírez, Joachim Büch, and Mario Albrecht
Nucleic Acids Research 37 (Web Server issue): W122-W128, 2009
-
DASMI: exchanging, annotating and assessing molecular interaction data
Hagen Blankenburg, Robert D. Finn, Andreas Prlić, Andrew M. Jenkinson, Fidel Ramírez, Dorothea Emig, Sven-Eric Schelhorn, Joachim Büch, Thomas Lengauer, and Mario Albrecht
Bioinformatics 25 (10): 1321-1328, 2009
-
An integrative approach for predicting interactions of protein regions
Sven-Eric Schelhorn, Thomas Lengauer, and Mario Albrecht
Bioinformatics 24 (16): i35-i41, 2008
-
Computing topological parameters of biological networks
Yassen Assenov, Fidel Ramírez, Sven-Eric Schelhorn, Thomas Lengauer, and Mario Albrecht
Bioinformatics 24 (2): 282-284, 2008
-
Integrating biological data - the Distributed Annotation System
Andrew M. Jenkinson, Mario Albrecht, Ewan Birney, Hagen Blankenburg, Thomas Down, Robert D. Finn, Henning Hermjakob, Tim J. P. Hubbard, Rafael C. Jimenez, Philip Jones, Andreas Kähäri, Eugene Kulesha, José R. Macías, Gabrielle A. Reeves, and Andreas Prlić
BMC Bioinformatics 9 (Suppl. 8): S3.1-7, 2008
-
Integrating expression data with domain interaction networks
Dorothea Emig, Melissa S. Cline, Thomas Lengauer, and Mario Albrecht
Bioinformatics 24 (21): 2546-2548, 2008
-
Integrative visual analysis of the effects of alternative splicing on protein domain interaction networks
Dorothea Emig, Melissa S. Cline, Karsten Klein, Anne Kunert, Petra Mutzel, Thomas Lengauer, and Mario Albrecht
Journal of Integrative Bioinformatics 5 (2): 101-115, 2008
-
Molecular basis of telaprevir resistance due to V36 and T54 mutations in the NS3-4A protease of HCV
Christoph Welsch, Francisco S. Domingues, Simone Susser, Iris Antes, Christoph Hartmann, Gabriele Mayr, Andreas Schlicker, Christoph Sarrazin, Mario Albrecht, Stefan Zeuzem, and Thomas Lengauer
Genome Biology 9 (1): R16 p., 2008
[PDF: Download: Welsch2008.pdf]
-
Sequence variants in IL10, ARPC2, and multiple other loci contribute to ulcerative colitis
Andre Franke, Tobias Balschun, Tom H. Karlsen, Jurgita Sventoraityte, Susanna Nikolaus, Gabriele Mayr, Francisco S. Domingues, Mario Albrecht, Michael Nothnagel, David Ellinghaus, Christian Sina, Clive M. Onnie, Rinse K. Weersma, Pieter C. F. Stokkers, Cisca Wijmenga, Maria Gazouli, David Strachan, Wendy L. McArdle, Séverine Vermeire, Paul Rutgeers, Philip Rosenstiel, Michael Krawczak, Morten H. Vatn, the IBSEN study group, Christopher G. Mathew, and Stefan Schreiber
Nature Genetics 40 (11): 1319-1323, 2008
-
Structure-function analysis of the NB-ARC domain of plant disease resistance proteins
Gerben Van Ooijen, Gabriele Mayr, Mobien M. A. Kasiem, Mario Albrecht, Ben J. C. Cornelissen, and Frank L. W. Takken
Journal of Experimental Botany 59 (6): 1383-1397, 2008
-
Transcomplementation, but not physical association of the CC-NB-ARC and LRR domains of tomato R protein Mi-1.2 is altered by mutations in the ARC2 subdomain
Gerben Van Ooijen, Gabriele Mayr, Mario Albrecht, Ben J. C. Cornelissen, and Frank L. W. Takken
Molecular Plant 1 (3): 401-410, 2008
-
Visualizing domain interaction networks and the impact of alternative splicing events
Dorothea Emig, Karsten Klein, Anne Kunert, Petra Mutzel, and Mario Albrecht
In: Proceedings of the 5th International Conference on BioMedical Visualization (MediVis): Information Visualization in Medical and Biomedical Informatics, London, United Kingdom, 2008, 36-43
-
FunSimMat: a comprehensive functional similarity database
Andreas Schlicker and Mario Albrecht
Nucleic Acids Research 36 (Database Issue): D434-D439, 2008
-
A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1
Jochen Hampe, Andre Franke, Philip Rosenstiel, Andreas Till, Markus Teuber, Klaus Huse, Mario Albrecht, Gabriele Mayr, Francisco M. De La Vega, Jason Briggs, Simone Günther, Natalie J. Prescott, Clive M. Onnie, Robert Häsler, Bence Sipos, Ulrich R. Fölsch, Thomas Lengauer, Matthias Platzer, Christopher G. Mathew, Michael Krawczak, and Stefan Schreiber
Nature Genetics 39 (2): 207-211, 2007
-
A network-based analysis of polyanion-binding proteins utilizing human protein arrays
Nazila Salamat-Miller, Jianwen Fang, Christopher W. Seidel, Yassen Assenov, Mario Albrecht, and C. Russell Middaugh
Journal of Biological Chemistry 282 (14): 10153-10163, 2007
-
Computational analysis of human protein interaction networks
Fidel Ramírez, Andreas Schlicker, Yassen Assenov, Thomas Lengauer, and Mario Albrecht
Proteomics 7 (15): 2541-2552, 2007
-
Functional evaluation of domain-domain interactions and human protein interaction networks
Andreas Schlicker, Carola Huthmacher, Fidel Ramírez, Thomas Lengauer, and Mario Albrecht
Bioinformatics 23 (7): 859-865, 2007
-
Identification of PatL1, a human homolog to yeast P body component Pat1
Nicoletta Scheller, Patricia Resa-Infante, Susana de la Luna, Rui Pedro Galao, Mario Albrecht, Lars Kaestner, Peter Lipp, Thomas Lengauer, Andreas Meyerhans, and Juana Díez
Biochimica et Biophysica Acta - Molecular Cell Research 1773 (12): 1786-1792, 2007
-
Structural and functional comparison of the non-structural protein 4B of flaviviridae
Christoph Welsch, Mario Albrecht, Jochen Maydt, E. Herrmann, M.W. Welker, C. Sarrazin, A. Scheidig, Thomas Lengauer, and S. Zeuzem
Journal of Molecular Graphics and Modeling 26 (2): 546-557, 2007
-
Systematic association mapping identifies NELL1 as a novel IBD disease gene
Andre Franke, Jochen Hampe, Philip Rosenstiel, Christoph Becker, Florian Wagner, Robert Häsler, Randall D. Little, Klaus Huse, Andreas Ruether, Tobias Balschun, Michael Wittig, Abdou ElSharawy, Gabriele Mayr, Mario Albrecht, Natalie J. Prescott, Clive M. Onnie, Hélène Fournier, Tim Keith, Uwe Radelof, Matthias Platzer, Christopher G. Mathew, Monika Stoll, Michael Krawczak, Peter Nürnberg, and Stefan Schreiber
PLoS ONE 2 (8): e691.1-13, 2007
-
The implications of alternative splicing in the ENCODE protein complement
Michael L. Tress, Pier L. Martelli, Adam Frankish, Gabrielle A. Reeves, Jan J. Wesselink, Corin Yeats, Páll Í. Ólason, Mario Albrecht, Hedi Hegyi, Alejandro Giorgetti, Domenico Raimondo, Julien Lagarde, Roman A. Laskowski, Gonzalo López, Michael I. Sadowski, James D. Watson, Piero Fariselli, Ivan Rossi, Alinda Nagy, Wang Kai, Zenia Størling, Massimiliano Orsini, Yassen Assenov, Hagen Blankenburg, Carola Huthmacher, Fidel Ramírez, Andreas Schlicker, France Denoued, Phil Jones, Samuel Kerrien, Sandra Orchard, Stylianos E. Antonarakis, Alexandre Reymond, Ewan Birney, Søren Brunak, Rita Casadio, Roderic Guigo, Jennifer Harrow, Henning Hermjakob, David T. Jones, Thomas Lengauer, Christine A. Orengo, László Patthy, Janet M. Thornton, Anna Tramontano, and Alfonso Valencia
Proceedings of the National Academy of Sciences 104 (13): 5495-5500, 2007
-
Variants in a novel epidermal collagen gene (COL29A1) are associated with atopic dermatitis
Cilla Söderhäll, Ingo Marenholz, Tamara Kerscher, Franz Rüschendorf, Jorge Esparza-Gordillo, Margitta Worm, Christoph Gruber, Gabriele Mayr, Mario Albrecht, Klaus Rohde, Herbert Schulz, Ulrich Wahn, Norbert Hubner, and Young-Ae Lee
PLoS Biology 5 (9): e242.1952-1961, 2007
[PDF: Download: Söderhäll.pdf]
-
GOTax: investigating biological processes and biochemical activities along the taxonomic tree
Andreas Schlicker, Jörg Rahnenführer, Mario Albrecht, Thomas Lengauer, and Francisco S. Domingues
Genome Biology 8 (3): R33.1-10, 2007
[PDF: Download: Schlicker2007.pdf]
-
A network-based analysis of polyanion-binding proteins utilizing yeast protein arrays
Nazila Salamat-Miller, Jianwen Fang, Christopher W. Seidel, Aaron M. Smalter, Yassen Assenov, Mario Albrecht, and C. Russell Middaugh
Molecular and Cellular Proteomics 5 (12): 2263-2278, 2006
-
Amino acid variations in hepatitis C virus p7 and sensitivity to antiviral combination therapy with amantadine in chronic hepatitis C
Ulrike Mihm, Natalia Grigorian, Christoph Welsch, Eva Herrmann, Bernd Kronenberger, Gerlinde Teuber, Michael von Wagner, Wolf-Peter Hofmann, Mario Albrecht, Thomas Lengauer, Stefan Zeuzem, and Christoph Sarrazin
Antiviral Therapy 11 (4): 507-519, 2006
-
An arginine/lysine-rich motif is crucial for VCP/p97-mediated modulation of ataxin-3 fibrillogenesis
Annett Boeddrich, Sébastien Gaumer, Annette Haacke, Nikolay Tzvetkov, Mario Albrecht, Bernd O. Evert, Eva C. Müller, Rudi Lurz, Peter Breuer, Nancy Schugardt, Stephanie Plaßmann, Kexiang Xu, John M. Warrick, Jaana Suopanki, Ullrich Wüllner, Ronald Frank, Ulrich F. Hartl, Nancy M. Bonini, and Erich E. Wanker
EMBO Journal 25 (7): 1547-1558, 2006
-
Combining protein structure prediction with experiments and functional information
Mario Albrecht
Doctoral dissertation, Universität des Saarlandes, 2006
-
Functional evaluation of domain-domain interactions and human protein interaction networks
Andreas Schlicker, Carola Huthmacher, Fidel Ramírez, Thomas Lengauer, and Mario Albrecht
In: German Conference on Bioinformatics (GCB 2006), Tübingen, Germany, 2006, 115-126
-
Mutations in the MutSalpha interaction interface of MLH1 can abolish DNA mismatch repair
Guido Plotz, Christoph Welsch, Luis Giron-Monzon, Peter Friedhoff, Mario Albrecht, Albrecht Piiper, Ricardo M. Biondi, Thomas Lengauer, Stefan Zeuzem, and Jochen Raedle
Nucleic Acids Research 34 (22): 6574-6586, 2006
[PDF: Download: Plotz.pdf]
-
Mutations in the NB-ARC domain of I-2 that impair ATP hydrolysis cause autoactivation
Wladimir I. Tameling, Jack H. Vossen, Mario Albrecht, Thomas Lengauer, Jan A. Berden, Michel A. Haring, Ben J.C. Cornelissen, and Frank L. W. Takken
Plant Physiology 140 (4): 1233-1245, 2006
-
Resistance proteins: molecular switches of plant defence
Frank L. W. Takken, Mario Albrecht, and Wladimir I. Tameling
Current Opinion in Plant Biology 9 (4): 383-390, 2006
-
Update on the domain architectures of NLRs and R proteins
Mario Albrecht and Frank L. W. Takken
Biochemical and Biophysical Research Communications 339 (2): 459-462, 2006
-
A new CARD15 mutation in Blau syndrome
Marjan M. Van Duist, Mario Albrecht, Marta Podswiadek, Daniela Giachino, Thomas Lengauer, Leonardo Punzi, and Mario De Marchi
European Journal of Human Genetics 13 (6): 742-747, 2005
-
An integrative approach to gain insights into the cellular function of human ataxin-2
Markus Ralser, Mario Albrecht, Ute Nonhoff, Thomas Lengauer, Hans Lehrach, and Sylvia Krobitsch
Journal of Molecular Biology 346 (1): 203-214, 2005
-
Ataxin-2 and huntingtin interact with endophilin-A complexes to function in plastin-associated pathways
Markus Ralser, Ute Nonhoff, Mario Albrecht, Thomas Lengauer, Erich E. Wanker, Hans Lehrach, and Sylvia Krobitsch
Human Molecular Genetics 14 (19): 2893-2909, 2005
-
Clinical significance of in vitro replication-enhancing mutations of the hepatitis C virus (HCV) replicon in patients with chronic HCV infection
Christoph Sarrazin, Ulrike Mihm, Eva Herrmann, Christoph Welsch, Mario Albrecht, Ulrike Sarrazin, Stella Traver, Thomas Lengauer, and Stefan Zeuzem
The Journal of Infectious Diseases 192 (10): 1710-1719, 2005
-
Clinical significance of in vitro replication-enhancing mutations of the hepatitis C virus (HCV) replicon in patients with chronic HCV infection.
Thomas Lengauer, Mario Albrecht, C. Sarrazin, U. Mihm, E. Herrmann, Christoph Welsch, U. Sarrazin, S. Traver, and S. Zeuzem
Journal of Infectious Diseases 192 (10): 1710-1719, 2005
-
Decomposing protein networks into domain-domain interactions
Mario Albrecht, Carola Huthmacher, Silvio C.E. Tosatto, and Thomas Lengauer
Bioinformatics 21 (Suppl. 2): ii220-ii221, 2005
-
Dissection of the inflammatory bowel disease transcriptome using genome-wide cDNA microarrays identifies novel candidate disease genes
Christine M. Costello, Nancy Mah, Robert Häsler, Philip Rosenstiel, Georg H. Waetzig, Andreas Hahn, Tim Lu, Yesim Gurbuz, Susanna Nikolaus, Mario Albrecht, Jochen Hampe, Ralph Lucius, Günther Klöppel, Holger Eickhoff, Hans Lehrach, Thomas Lengauer, and Stefan Schreiber
PLoS Medicine 2 (8): 771-787, 2005
-
Diversity and functional plasticity of eukaryotic selenoproteins: Identification and characterization of the SelJ family
Sergi Castellano, Alexey V. Lobanov, Charles Chapple, Sergey V. Novoselov, Mario Albrecht, Deame Hua, Alain Lescure, Thomas Lengauer, Alain Krol, Vadim N. Gladyshev, and Roderic Guigó
Proceedings of the National Academy of Sciences 102 (45): 16188-16193, 2005
-
Genetics of Crohn disease, an archetypal inflammatory barrier disease
Stefan Schreiber, Philip Rosenstiel, Mario Albrecht, Jochen Hampe, and Michael Krawczak
Nature Reviews Genetics 6 (5): 376-388, 2005
-
Sarcoidosis is associated with a truncating splice site mutation in BTNL2
Ruta Valentonyte, Jochen Hampe, Klaus Huse, Philip Rosenstiel, Mario Albrecht, Annette Stenzel, Marion Nagy, Karoline I. Gaede, Andre Franke, Robert Haesler, Andreas Koch, Thomas Lengauer, Dirk Seegert, Norbert Reiling, Stefan Ehlers, Eberhard Schwinger, Mathias Platzer, Michael Krawczak, Joachim Müller-Quernheim, Manfred Schürmann, and Stefan Schreiber
Nature Genetics 37 (4): 357-364, 2005
-
Structural and functional analysis of a novel mutation of CYP21B in a heterozygote carrier of 21-hydroxylase deficiency
Jörg Bojunga, Christoph Welsch, Iris Antes, Mario Albrecht, Thomas Lengauer, and Stefan Zeuzem
Human Genetics 117 (6): 558-564, 2005
-
The HIN domain of IFI-200 proteins consists of two OB folds
Mario Albrecht, Divaker Choubey, and Thomas Lengauer
Biochemical and Biophysical Research Communications 327 (3): 679-687, 2005
-
LRRK2 mutations and parkinsonism
Mario Albrecht
The Lancet 365 (9466): 1230 p., 2005
-
Genetic variation in DLG5 is associated with inflammatory bowel disease
Monika Stoll, Brit Corneliussen, Christine M. Costello, Georg H. Waetzig, Bjorn Mellgard, W. Andreas Koch, Philip Rosenstiel, Mario Albrecht, Peter J.P. Croucher, Dirk Seegert, Susanna Nikolaus, Jochen Hampe, Thomas Lengauer, Stefan Pierrou, Ulrich R. Foelsch, Christopher G. Mathew, Maria Lagerstrom-Fermer, and Stefan Schreiber
Nature Genetics 36 (5): 376-380, 2004
-
Novel Sm-like proteins with long C-terminal tails and associated methyltransferases
Mario Albrecht and Thomas Lengauer
FEBS Letters 569 (1-3): 18-26, 2004
-
Structural and functional analysis of ataxin-2 and ataxin-3
Mario Albrecht, Michael Golatta, Ullrich Wüllner, and Thomas Lengauer
European Journal of Biochemistry 271 (15): 3155-3170, 2004
-
Survey on the PABC recognition motif PAM2
Mario Albrecht and Thomas Lengauer
Biochemical and Biophysical Research Communications 316 (1): 129-138, 2004
-
Disease-associated variants in PYPAF1 and NOD2 result in similar alterations of conserved sequence
Mario Albrecht, Thomas Lengauer, and Stefan Schreiber
Bioinformatics 19: 2171-2175, 2003. Note: In press.
-
Identification of mammalian orthologs associates PYPAF5 with distinct functional roles
Mario Albrecht, Francisco S. Domingues, Stefan Schreiber, and Thomas Lengauer
FEBS Letters 538 (1-3): 173-177, 2003
-
Pyranose oxidase identified as a member of the GMC oxidoreductase family
Mario Albrecht and Thomas Lengauer
Bioinformatics 19 (10): 1216-1220, 2003
-
Simple consensus procedures are effective and sufficient in secondary structure prediction
Mario Albrecht, Silvio C.E. Tosatto, Thomas Lengauer, and Giorgio Valle
Protein Engineering 16 (7): 459-462, 2003
-
Structural localization of disease-associated sequence variations in the NACHT and LRR domains of PYPAF1 and NOD2
Mario Albrecht, Francisco S. Domingues, Stefan Schreiber, and Thomas Lengauer
FEBS Letters 554 (3): 520-528, 2003
-
Structural modeling of ataxin-3 reveals distant homology to adaptins
Mario Albrecht, Daniel Hoffmann, Bernd O. Evert, Ina Schmitt, Ullrich Wüllner, and Thomas Lengauer
Proteins: Structure, Function, and Genetics 50 (2): 355-370, 2003
-
A new method for the fast solution of protein-3D-structures, combining experiments and bioinformatics
Daniel Hoffmann, Volker Schnaible, Stephan, Wefing, Mario Albrecht, Daniel Hanisch, and Ralf Zimmer
In: Coupling of Biological and Electronic Systems: Proceedings of the 2nd Caesarium, Bonn, 1-3 November 2000, Bonn, Germany, 2002, 59-78
-
Improving fold recognition of protein threading by experimental distance constraints
Mario Albrecht, Daniel Hanisch, Ralf Zimmer, and Thomas Lengauer
In Silico Biology 2 (3): 325-337, 2002
[PDF: Download: mario albrecht.pdf]