Publications
MPI-INF D3 Publications
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| | 2012 | Welsch, Christoph [Schweizer, Sabine] [Shimakami, Testsuro] [Domingues, Francisco S.] [Kim, Seungtaek] [Lemon, Stanley, M.] [Antes, Iris] | Ketoamide Resistance and Hepatitis C Virus Fitness in Val55 Variants of the NS3 Serine Protease In: Antimicrobial Agents and Chemotherapy [56], 1907-1915 | Journal Article | | |||
| 2012 | [Welsch, Christoph] [Shimakami, Tetsuro] [Hartmann, Christoph] [Yang, Yan] [Domingues, Francisco S.] Lengauer, Thomas [Zeuzem, Stefan] [Lemon, Stanley M.] | Peptidomimetic Escape Mechanisms Arise via Genetic Diversity in the Ligand-Binding Site of the Hepatitis C Virus NS3/4A Serine Protease In: Gastroenterology [142], 654-663 | Journal Article | | |||||
| | 2011 | [Welker, M.-W.] Welsch, Christoph [Ochs, D.] [Hofmann, W. P.] [Herrmann, E.] [Piiper, A.] [Hartmann, R. W.] [Zeuzem, S.] [Sarrazin, C.] [Kronenberger, Bernd] | Comparison of Envelope 2 CD81 binding regions in PBMC-derived versus serum-derived hepatitis C virus isolates: higher conservation of CD81 region 2 in PBMC isolates In: Journal of Viral Hepatitis [18], 181-192 | Journal Article | | |||
| 2011 | [Hofmann, Wolf Peter] [Chung, Tje Lin] [Osbahr, Carola] [Susser, Simone] [Karey, Ursel] [Mihm, Ulrike] Welsch, Christoph [Lötsch, Jörn] [Sarrazin, Christoph] [Zeuzem, Stefan] [Herrmann, Eva] | Impact of ribavirin on HCV replicon RNA decline during treatment with interferon-α and the protease inhibitors boceprevir or telaprevir In: Antiviral Therapy [16], 695-704 | Journal Article | | |||||
| | 2011 | [Shimakami, Tetsuro] Welsch, Christoph [Yamane, Daisuke] [McGivern, David R.] [Yi, MinKyung] [Zeuzem, Stefan] [Lemon, Stanley M.] | Protease Inhibitor-Resistant Hepatitis C Virus Mutants With Reduced Fitness From Impaired Production of Infectious Virus In: Gastroenterology [140], 667-675 | Journal Article | | |||
| 2010 | [Welker, Martin-Walter] [Welsch, Christoph] [Meyer, Aline] Antes, Iris Albrecht, Mario [Forestier, Nicole] [Kronenberger, Bernd] Lengauer, Thomas [Piiper, Albrecht] [Zeuzem, Stefan] [Sarrazin, Christoph] | Dimerization of the hepatitis C virus nonstructural protein 4B depends on the integrity of an aminoterminal basic leucine zipper In: Protein Science [19], 1327-1336 | Journal Article | | |||||
| | 2010 | [Mihm, Ulrike] [Hofmann, W.P.] Welsch, Christoph [Polta, A.] Lengauer, Thomas [Zeuzem, Stefan] [Sarrazin, Christoph] [Herrmann, E.] | Effect of ribavirin on the frequency of RNAse L cleavage sites within the hepatitis C viral genome In: Journal of Viral Hepatitis [17], 217-221 | Journal Article | | |||
| 2009 | [Susser, Simone] Welsch, Christoph [Wang, Yalan] [Zettler, Markus] Domingues, Francisco S. [Karey, Ursula] [Hughes, Eric] [Ralston, Robert] [Tong, Xiao] [Herrmann, Eva] [Zeuzem, Stefan] [Sarrazin, Christoph] | Characterization of resistance to the protease inhibitor boceprevir in hepatitis C virus-infected patients. In: Hepatology [50], 1709-1718 | Journal Article | | |||||
| | 2009 | [Mihm, Ulrike] [Ackermann, Oliver] Welsch, Christoph [Herrmann, Eva] [Hofmann, Wolf Peter] [Grigorian, Natalia] [Welker, Martin Walter] Lengauer, Thomas [Zeuzem, Stefan] [Sarrazin, Christoph] | Clinical relevance of the 2'-5'-oligoadenylate synthetase/RNase L system for treatment response in chronic hepatitis C In: Journal of Hepatology [50], 49-58 | Journal Article | | |||
| 2008 | [Welsch, Christoph] Domingues, Francisco S. [Susser, Simone] Antes, Iris Hartmann, Christoph Mayr, Gabriele Schlicker, Andreas [Sarrazin, Christoph] Albrecht, Mario [Zeuzem, Stefan] Lengauer, Thomas |  | Molecular basis of telaprevir resistance due to V36 and T54 mutations in the NS3-4A protease of HCV In: Genome Biology [9], R16 | Journal Article | | ||||
| | 2007 | [Welker, Martin W.] [Hofmann, Wolf-Peter] [Welsch, Christoph] [von Wagner, Michael] [Herrmann, Eva] [Lengauer, Thomas] [Zeuzem, Stefan] [Sarrazin, Christoph] | Correlation nonstructural (NS)4B amino acid variations with initial viral kinetics during interferon-alpha-based therapy in HCV-1b-infected patients In: Journal of Viral Hepatitis [14], 338-349 | Journal Article | | |||
| 2007 | [Hofmann, Wolf Peter] Welsch, Christoph [Takahashi, Yoshitomo] [Miyajima, Hiroaki] [Mihm, Ulrike] [Krick, Christoph] [Zeuzem, Stefan] [Sarrazin, Christoph] | Identification and in silico characterization of a novel compound heterozygosty associated with hereditary aceruloplasminemia In: Scandinavian Journal of Gastroenterology [42], 1088-1094 | Journal Article | | |||||
| | 2007 | [Hofmann, Wolf Peter] [Fernandez, B.] [Herrmann, E.] Welsch, Christoph [Mihm, Ulrike] [Kronenberg, B.] [Feldmann, G.] [Spengler, U.] [Zeuzem, Stefan] [Sarrazin, Christoph] | Somatic hypermutation and mRNA expression levels of the BCL-6 gene in patients with hepatitis C virus-associated lymphoproliferative diseases In: Journal of Viral Hepatitis [14], 484-491 | Journal Article | | |||
| 2007 | Welsch, Christoph Albrecht, Mario Maydt, Jochen [Herrmann, E.] [Welker, M.W.] [Sarrazin, C.] [Scheidig, A.] Lengauer, Thomas Zeuzem, S. | Structural and functional comparison of the non-structural protein 4B of flaviviridae In: Journal of Molecular Graphics and Modeling [26], 546-557 | Journal Article | | |||||
| | 2006 | [Mihm, Ulrike] [Grigorian, Natalia] [Welsch, Christoph] [Herrmann, Eva] [Kronenberger, Bernd] [Teuber, Gerlinde] [von Wagner, Michael] [Hofmann, Wolf-Peter] Albrecht, Mario Lengauer, Thomas [Zeuzem, Stefan] [Sarrazin, Christoph] | Amino acid variations in hepatitis C virus p7 and sensitivity to antiviral combination therapy with amantadine in chronic hepatitis C In: Antiviral Therapy [11], 507-519 | Journal Article | | |||
| 2006 | [Plotz, Guido] [Welsch, Christoph] [Giron-Monzon, Luis] [Friedhoff, Peter] Albrecht, Mario [Piiper, Albrecht] Biondi, Ricardo M. Lengauer, Thomas [Zeuzem, Stefan] [Raedle, Jochen] | | Mutations in the MutSalpha interaction interface of MLH1 can abolish DNA mismatch repair In: Nucleic Acids Research [34], 6574-6586 | Journal Article | | ||||
| | 2005 | [Sarrazin, Christoph] [Mihm, Ulrike] [Herrmann, Eva] [Welsch, Christoph] Albrecht, Mario [Sarrazin, Ulrike] [Traver, Stella] Lengauer, Thomas [Zeuzem, Stefan] | Clinical significance of in vitro replication-enhancing mutations of the hepatitis C virus (HCV) replicon in patients with chronic HCV infection In: The Journal of Infectious Diseases [192], 1710-1719 | Journal Article | | |||
| 2005 | Lengauer, Thomas Albrecht, Mario [Sarrazin, C.] [Mihm, U.] [Herrmann, E.] Welsch, Christoph [Sarrazin, U.] [Traver, S.] [Zeuzem, S.] | Clinical significance of in vitro replication-enhancing mutations of the hepatitis C virus (HCV) replicon in patients with chronic HCV infection. In: Journal of Infectious Diseases [192], 1710-1719 | Journal Article | | |||||
| | 2005 | [Bojunga, Jörg] [Welsch, Christoph] Antes, Iris Albrecht, Mario Lengauer, Thomas [Zeuzem, Stefan] | Structural and functional analysis of a novel mutation of CYP21B in a heterozygote carrier of 21-hydroxylase deficiency In: Human Genetics [117], 558-564 | Journal Article | | |||
| 2004 | [Hofmann, W.P.] [Herrmann, E.] [Kronenberger, B.] Merkwirth, Christian Welsch, Christoph Lengauer, Thomas [Zeuzem, S.] [Sarrazin, C.] | Association of HCV-related mixed cryoglobulinemia with specific mutational patterns of the HCV E2 protein and CD81 expression on peripheral B lymphocytes In: Blood [104], 1228-1229 | Journal Article | | |||||
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