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2014 | Pironti, Alejandro Pfeifer, Nico Kaiser, Rolf Walter, Hauke Lengauer, Thomas | Accurate prediction of drug-exposure without using established drug-resistance mutations In: Antiviral Therapy, A75 | Poster | ![]() | |||||
![]() | ![]() | 2014 | Pironti, Alejandro Pfeifer, Nico Kaiser, Rolf Walter, Hauke Lengauer, Thomas | Improved HIV-1 drug-exposure reconstruction with linear support vector machines In: Reviews in Antiviral Therapy & Infectious Diseases, 67 | Poster | ![]() | |||
2014 | Pironti, Alejandro Pfeifer, Nico [Kaiser, Rolf] [Walter, Hauke] Lengauer, Thomas | Improved therapy-success prediction with GSS estimated from clinical HIV-1 sequences In: Abstract Supplement of the HIV Drug Therapy Glasgow Congress 2014, 155 | Poster | ![]() | |||||
![]() | ![]() | 2012 | [Obermeier, Martin] Pironti, Alejandro [Berg, Thomas] [Braun, Patrick] [Däumer, Martin] [Eberle, Josef] [Ehret, Robert] [Kaiser, Rolf] [Kleinkauf, Niels] [Korn, Klaus] [Kücherer, Claudia] [Müller, Harm] [Noah, Christian] [Stürmer, Martin] Thielen, Alexander [Wolf, Eva] [Walter, Hauke] | HIV-GRADE: A Publicly Available, Rules-Based Drug Resistance Interpretation Algorithm Integrating Bioinformatic Knowledge In: Intervirology [55], 102-107 | Journal Article | ![]() | |||
2010 | Weisser, Hendrik Altmann, André [Sierra, Saleta] [Incardona, Francesca] [Struck, Daniel] [Sönnerborg, Anders] [Kaiser, Rolf] [Zazzi, Maurizio] [Tschochner, Monika] [Walter, Hauke] Lengauer, Thomas | Only Slight Impact of Predicted Replicative Capacity for Therapy Response Prediction In: PLoSOne [5], e9044,1-e9044,10 | Electronic Journal Article | ![]() | |||||
![]() | ![]() | 2009 | Thielen, Alexander [Sichtig, Nadine] [Braun, Patrick] [Däumer, Martin] [Walter, Hauke] [Noah, Christian] [Wolf, Eva] [Müller, Harm] [Stürmer, Martin] Lengauer, Thomas [Kaiser, Rolf] [Obermeier, Martin] | Performance of genotypic coreceptor measurement using geno2pheno[coreceptor] in B- and non-B HIV subtypes in a large cohort of therapy-experienced patients in Germany In: Reviews in Antiviral Therapy, 99-99 | Poster | ![]() | |||
2008 | [Obermeier, Martin] [Berg, Thomas] [Sichtig, Nadine] [Braun, Patrick] [Däumer, Martin] [Walter, Hauke] [Noah, Christian] [Wolf, Eva] [Müller, Harm] [Stürmer, Martin] Thielen, Alexander [Kaiser, Rolf] | Determination of HIV-1 co-receptor usage in German patients – comparison of genotypic methods with the TROFILE® phenotypic assay In: Abstracts of the Ninth International Congress on Drug Therapy in HIV Infection, 123 | Poster | ![]() | |||||
![]() | ![]() | 2008 | [Obermeier, Martin] [Sichtig, Nadine] [Braun, Patrick] [Däumer, Martin] [Walter, Hauke] [Noah, Christian] [Wolf, Eva] [Müller, Harm] [Stürmer, Martin] [Kaiser, Rolf] Thielen, Alexander | Determination of HIV-1 coreceptor usage in German patients - comparison of genotypic methods with the TROFILE phenotypic assay In: Antiviral Therapy, A112 | Poster | ![]() | |||
2007 | Altmann, Andre [Däumer, Martin] Sing, Tobias [Beerenwinkel, Niko] [Walter, Hauke] [Kaiser, Rolf] Lengauer, Thomas | Validation of geno2pheno and THEO on a large independent clinical dataset In: Proceedings of the 5th European HIV Drug Resistance Workshop, - | Poster | ![]() | |||||
![]() | ![]() | 2005 | Sing, Tobias [Svicher, Valentina] Beerenwinkel, Niko [Ceccherini-Silberstein, Francesca] [Däumer, Martin] [Kaiser, Rolf] [Walter, Hauke] [Korn, Klaus] [Hoffmann, Daniel] [Oette, Mark] [Rockstroh, Jürgen K.] Fätkenheuer, Gerd [Perno, Carlo-Federico] Lengauer, Thomas | Characterization of novel HIV Drug Resistance Mutations using clustering, multidimensional scaling and SVM-based feature ranking In: Knowledge Discovery in Databases: PKDD 2005., 285-296 | Proceedings Article | ![]() | |||
2005 | [Beerenwinkel, Niko] Sing, Tobias Lengauer, Thomas Rahnenführer, Jörg Roomp, Kirsten Savenkov, Igor [Fischer, Roman] [Hoffmann, Daniel] [Selbig, Joachim] [Korn, Klaus] [Walter, Hauke] [Berg, Thomas] [Braun, Patrick] [Fätkenheuer, Gerd] [Oette, Mark] [Rockstroh, Jürgen] [Kupfer, Bernd] [Kaiser, Rolf] [Däumer, Martin] | Computational methods for the design of effective therapies against drug resistant HIV strains In: Bioinformatics [21], 3943-3950 | Journal Article | ![]() | |||||
![]() | ![]() | 2003 | Beerenwinkel, Niko [Däumer, Martin] [Kaiser, Rolf] [Walter, Hauke] [Korn, Klaus] [Hoffmann, Daniel] [Selbig, Joachim] Lengauer, Thomas | Estimating effective drug combinations against drug-resistant mutants from genotypes In: Proceedings of the 1st European HIV Drug Resistamce Workshop, 18-18 | Proceedings Article | ![]() | |||
2003 | Beerenwinkel, Niko [Däumer, Martin] [Oette, Mark] [Korn, Klaus] [Hoffmann, Daniel] [Kaiser, Rolf] Lengauer, Thomas [Selbig, Joachim] [Walter, Hauke] | Geno2pheno: estimating phenotypic drug resistance from HIV-1 genotypes In: Nucleic Acids Research [31], 3850-3855 | Journal Article | ![]() | |||||
![]() | ![]() | 2003 | Beerenwinkel, Niko Lengauer, Thomas [Däumer, Martin] [Kaiser, Rolf] [Walter, Hauke] [Korn, Klaus] [Hoffmann, Daniel] [Selbig, Joachim] | Methods for optimizing antiviral combination therapies In: Bioinformatics [19], i16-i25 | Journal Article | ![]() | |||
2003 | [Wolf, Katharina] [Walter, Hauke] Beerenwinkel, Niko [Keulen, Wilco] [Kaiser, Rolf] [Hoffmann, Daniel] Lengauer, Thomas [Selbig, Joachim] [Vandamme, Anne-Mieke] [Korn, Klaus] [Schmidt, Barbara] | Tenofovir resistance and resensitization In: Antimicrobial Agents and Chemotherapy [47], 3478-3484 | Journal Article | ![]() | |||||
![]() | ![]() | 2002 | Beerenwinkel, Niko [Schmidt, Barbara] [Walter, Hauke] [Kaiser, Rolf] Lengauer, Thomas [Hoffmann, Daniel] [Korn, Klaus] [Selbig, Joachim] | Diversity and complexity of HIV-1drug resistance: A bioinformatics approach to predicting phenotype from genotype In: Proceedings of the National Academy of Sciences [99], 8271-8276 | Journal Article | ![]() | |||
2002 | Beerenwinkel, Niko Lengauer, Thomas [Däumer, Martin] [Sierra, S.] [Schmidt, Barbara] [Walter, Hauke] [Korn, Klaus] [Oette, Mark] Fätkenheuer, Gerd [Rockstroh, J.] [Hoffmann, Daniel] [Kaiser, Rolf] [Selbig, Joachim] | Geno2pheno is predictive of short-term virological response In: Proceedings from the 5th International Workshop on HIV Drug Resistance & Treatment Strategies, 74-74 | Proceedings Article | ![]() | |||||
![]() | ![]() | 2002 | Beerenwinkel, Niko Lengauer, Thomas [Schmidt, Barbara] [Walter, Hauke] [Kaiser, Rolf] [Hoffmann, Daniel] [Korn, Klaus] [Selbig, Joachim] | Quantitative phenotype prediction by support vector machines In: Proceedings from the 5th International Workshop on HIV Drug resistance & Treatment Strategies, 97 | Proceedings Article | ![]() | |||
2001 | Beerenwinkel, Niko [Schmidt, Barbara] [Walter, Hauke] [Kaiser, Rolf] Lengauer, Thomas [Hoffmann, Daniel] [Korn, Klaus] [Selbig, Joachim] | Geno2pheno: A system for the interpretation of genotypic HIV Drug resistance tests In: IEEE Intelligent Systems [16], 35-41 | Journal Article | ![]() | |||||
![]() | ![]() | 2001 | Beerenwinkel, Niko [Däumer, Martin] [Hoffmann, Daniel] [Kaiser, Rolf] [Korn, Klaus] Lengauer, Thomas [Schmidt, Barbara] [Walter, Hauke] [Selbig, Joachim] | Neue Wege zur Optimierung von Anti-HIV Therapien In: BIOforum [24], 912-914 | Journal Article | ![]() | |||
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