MPI-INF D3 Publications: Journal Article: Arevir: A Secure Platform for Designing Personalized Antiretroviral Therapies Against {HIV}

Journal Article
@Article
Artikel in Fachzeitschrift

Show entries of:

this year (2023) | last year (2022) | two years ago (2021) | Notes URL

Action:

Options:

Library locked

Goto entry point

Author, Editor(s)

Author(s):

Roomp, Kirsten
Beerenwinkel, Niko
Sing, Tobias
Schülter, Eugen
Büch, Joachim
Sierra-Aragon, Saleta
Däumer, Martin
Hoffmann, Daniel
Kaiser, Rolf
Lengauer, Thomas
Selbig, Joachim

dblp
dblp
dblp
dblp
dblp
dblp
dblp
dblp
dblp
dblp
dblp

Not MPG Author(s):

Schülter, Eugen
Sierra-Aragon, Saleta
Däumer, Martin
Hoffmann, Daniel
Kaiser, Rolf
Selbig, Joachim

BibTeX cite key*:

Roomp2006

Title

Title*:

Arevir: A Secure Platform for Designing Personalized Antiretroviral Therapies Against HIV

Journal

Journal Title*:	Lecture Notes in Computer Science	Journal's URL:	http://www.springerlink.com/content/f5121n1715k50631/
Download URL for the article:	http://www.springerlink.com/content/f5121n1715k50631/fulltext.pdf	Language:	English

Publisher

Publisher's Name:	Springer	Publisher's URL:	http://www.springer.com
Publisher's Address:	Berlin, Germany	ISSN:	0302-9743

Vol, No, pp, Date

Volume*:	4075	Number:
Publishing Date:	July 2006
Pages*:	185-194	Number of VG Pages:
Page Start:		Page End:
Sequence Number:		DOI:

Note:
(LaTeX) Abstract:	Despite the availability of antiretroviral combination therapies, success in drug treatment of HIV-infected patients is limited. One reason for therapy failure is the development of drug-resistant genetic variants. In principle, the viral genomic sequence provides resistance information and could thus guide the selection of an optimal drug combination. In practice however, the benefit of this procedure is impaired by (1) the difficulty in inferring the clinically relevant information from the genotype of the virus and (2) the restricted availability of this information. We have developed a secure platform for collaborative research aimed at optimizing anti-HIV therapies, called Arevir. A relational database schema was designed and implemented together with a web-based user interface. Our system provides a basis for monitoring patients, decision-support, and computational analyses. Thus, it merges clinical, diagnostic and bioinformatics efforts to exploit genomic and patient therapy data in clinical practice.
URL for the Abstract:	http://www.springerlink.com/content/f5121n1715k50631/
Categories, Keywords:
HyperLinks / References / URLs:
Copyright Message:
Personal Comments:
Download Access Level:	Intranet

Correlation

MPG Unit:	Max-Planck-Institut für Informatik

MPG Subunit:	Computational Biology and Applied Algorithmics
Appearance:	MPII WWW Server, MPII FTP Server, MPG publications list, university publications list, working group publication list, Fachbeirat, VG Wort

BibTeX Entry:

@ARTICLE{Roomp2006,
AUTHOR = {Roomp, Kirsten and Beerenwinkel, Niko and Sing, Tobias and Sch{\"u}lter, Eugen and B{\"u}ch, Joachim and Sierra-Aragon, Saleta and D{\"a}umer, Martin and Hoffmann, Daniel and Kaiser, Rolf and Lengauer, Thomas and Selbig, Joachim},
TITLE = {Arevir: A Secure Platform for Designing Personalized Antiretroviral Therapies Against {HIV}},
JOURNAL = {Lecture Notes in Computer Science},
PUBLISHER = {Springer},
YEAR = {2006},
VOLUME = {4075},
PAGES = {185--194},
ADDRESS = {Berlin, Germany},
MONTH = {July},
ISBN = {0302-9743},
}

Entry last modified by Christine Kiesel, 01/27/2015

Edit History (please click the blue arrow to see the details)

	Editor(s) [Library]	Created 03/13/2007 18:32:24
Revisions 3. 2. 1. 0.	Editor(s) Christine Kiesel Christine Kiesel Joachim Büch Joachim Büch	Edit Dates 02.04.2007 09:27:49 30.03.2007 16:07:45 13.03.2007 18:33:52 13.03.2007 18:32:24