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MPI-INF D3 Publications

MPI-INF D3 Publications

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Albrecht, MarioLRRK2 mutations and parkinsonism
In: The Lancet [365], 1230
Albrecht, Mario
Choubey, Divaker
Lengauer, Thomas
The HIN domain of IFI-200 proteins consists of two OB folds
In: Biochemical and Biophysical Research Communications [327], 679-687
Albrecht, Mario
Huthmacher, Carola
Tosatto, Silvio C.E.
Lengauer, Thomas
Decomposing protein networks into domain-domain interactions
In: Bioinformatics [21], ii220-ii221
Antes, Iris
Merkwirth, Christian
Lengauer, Thomas
POEM: Parameter Optimization using Ensemble Methods: Application to target specific scoring functions
In: Journal of Chemical Information and Modeling [45], 1291-1302
Balduin, Melanie
Beerenwinkel, Niko
Sierra, Saleta
Däumer, Martin
Rockstroh, Jürgen
Oette, Mark
Fätkenheuer, Gerd
Kupfer, Bernd
Hoffmann, Daniel
Selbig, Joachim
Pfister, Herbert
Kaiser, Rolf
Evolution of HIV resistance during treatment interruption in experienced patients and after restarting a new therapy
In: J Clin Virol [34], 277-287
Beerenwinkel, Niko
Däumer, Martin
Sing, Tobias
Rahnenführer, Jörg
Lengauer, Thomas
Selbig, Joachim
Hoffmann, Daniel
Kaiser, Rolf
Estimating HIV evolutionary pathways and the genetic barrier to drug resistance
In: The Journal of Infectious Diseases [191], 1953-1960
Beerenwinkel, Niko
Rahnenführer, Jörg
Däumer, Martin
Hoffmann, Daniel
Kaiser, Rolf
Selbig, Joachim
Lengauer, Thomas
Learning multiple evolutionary pathways from cross-sectional data
In: Journal of Computational Biology [12], 584-598
Beerenwinkel, Niko
Rahnenführer, Jörg
Kaiser, Rolf
Hoffmann, Daniel
Selbig, Joachim
Lengauer, Thomas
Mtreemix: a software package for learning and using mixture models of mutagenetic trees
In: Bioinformatics [21], 2106-2107
Beerenwinkel, Niko
Sing, Tobias
Lengauer, Thomas
Rahnenführer, Jörg
Roomp, Kirsten
Savenkov, Igor
Fischer, Roman
Hoffmann, Daniel
Selbig, Joachim
Korn, Klaus
Walter, Hauke
Berg, Thomas
Braun, Patrick
Fätkenheuer, Gerd
Oette, Mark
Rockstroh, Jürgen
Kupfer, Bernd
Kaiser, Rolf
Däumer, Martin
Computational methods for the design of effective therapies against drug resistant HIV strains
In: Bioinformatics [21], 3943-3950
Bock, Christoph
Lengauer, Thomas
Reither, Sabine
Mikeska, Thomas
Paulsen, Martina
Walter, Jörn
Attachment IconBiQ Analyzer: visualization and quality control for DNA methylation data from bisulfite sequencing
In: Bioinformatics [21], 4067-4068
Bojunga, Jörg
Welsch, Christoph
Antes, Iris
Albrecht, Mario
Lengauer, Thomas
Zeuzem, Stefan
Structural and functional analysis of a novel mutation of CYP21B in a heterozygote carrier of 21-hydroxylase deficiency
In: Human Genetics [117], 558-564
Castellano, Sergi
Lobanov, Alexey V.
Chapple, Charles
Novoselov, Sergey V.
Albrecht, Mario
Hua, Deame
Lescure, Alain
Lengauer, Thomas
Krol, Alain
Gladyshev, Vadim N.
Guigó, Roderic
Diversity and functional plasticity of eukaryotic selenoproteins: Identification and characterization of the SelJ family
In: Proceedings of the National Academy of Sciences [102], 16188-16193
Costello, Christine M.
Mah, Nancy
Häsler, Robert
Rosenstiel, Philip
Waetzig, Georg H.
Hahn, Andreas
Lu, Tim
Gurbuz, Yesim
Nikolaus, Susanna
Albrecht, Mario
Hampe, Jochen
Lucius, Ralph
Klöppel, Günther
Eickhoff, Holger
Lehrach, Hans
Lengauer, Thomas
Schreiber, Stefan
Dissection of the inflammatory bowel disease transcriptome using genome-wide cDNA microarrays identifies novel candidate disease genes
In: PLoS Medicine [2], 771-787
Das, Ani V.
James, Jackson
Rahnenführer, Jörg
Thoresona, Wallace B.
Bhattacharyaa, Sumitra
Zhao, Xing
Ahmad, Iqbal
Retinal properties and potential of the adult mammalian ciliary epithelium stem cells
In: Vision Research [45], 1653-1666
Gu, Wei
Kofler, Michael
Antes, Iris
Freund, Christian
Helms, Volkhard
Alternative Binding Modes of Polyproline Peptides Binding to the GYF Domain
In: Biochemistry [44], 6404-6415
Hahn, Andreas
Rahnenführer, Jörg
Talwar, Priti
Lengauer, Thomas
Confirmation of human protein interaction data by human expression data
In: BMC Bioinformatics [6], 1-11
Hessler, G.
Zimmermann, M.
Matter, H.
Evers, A.
Naumann, T.
Lengauer, Thomas
Rarey, M.
Multiple-Ligand-Based Virtual Screening: Methods and Applications of the MTree Approach
In: Journal of Medicinal Chemistry [48], 6575-6584
Lengauer, Thomas
Albrecht, Mario
Sarrazin, C.
Mihm, U.
Herrmann, E.
Welsch, Christoph
Sarrazin, U.
Traver, S.
Zeuzem, S.
Clinical significance of in vitro replication-enhancing mutations of the hepatitis C virus (HCV) replicon in patients with chronic HCV infection.
In: Journal of Infectious Diseases [192], 1710-1719
Lengauer, Thomas
Merkwirth, Christian
Automatic Generation of complementary descriptors with molecular graph networks
In: Journal of Chemical Information and Modeling [45], 1159-1168
Rahnenführer, JörgClustering algorithms and other exploratory methods for microarray data analysis
In: Methods of Information in Medicine [44], 444-448
Rahnenführer, JörgImage analysis for cDNA microarrays
In: Methods of Information in Medicine [44], 405-407
Rahnenführer, Jörg
Beerenwinkel, Niko
Schulz, Wolfgang A.
Hartmann, Christian
von Deimling, Andreas
Wullich, Bernd
Lengauer, Thomas
Estimating cancer survival and clinical outcome based on genetic tumor progression scores
In: Bioinformatics [21], 2438-2446
Ralser, Markus
Albrecht, Mario
Nonhoff, Ute
Lengauer, Thomas
Lehrach, Hans
Krobitsch, Sylvia
An integrative approach to gain insights into the cellular function of human ataxin-2
In: Journal of Molecular Biology [346], 203-214
Ralser, Markus
Nonhoff, Ute
Albrecht, Mario
Lengauer, Thomas
Wanker, Erich E.
Lehrach, Hans
Krobitsch, Sylvia
Ataxin-2 and huntingtin interact with endophilin-A complexes to function in plastin-associated pathways
In: Human Molecular Genetics [14], 2893-2909
Sarrazin, Christoph
Mihm, Ulrike
Herrmann, Eva
Welsch, Christoph
Albrecht, Mario
Sarrazin, Ulrike
Traver, Stella
Lengauer, Thomas
Zeuzem, Stefan
Clinical significance of in vitro replication-enhancing mutations of the hepatitis C virus (HCV) replicon in patients with chronic HCV infection
In: The Journal of Infectious Diseases [192], 1710-1719
Schreiber, Stefan
Rosenstiel, Philip
Albrecht, Mario
Hampe, Jochen
Krawczak, Michael
Genetics of Crohn disease, an archetypal inflammatory barrier disease
In: Nature Reviews Genetics [6], 376-388
Ulmschneider, Sarah
Mueller-Vieira, Ursula
Klein, Christian D.
Antes, Iris
Lengauer, Thomas
Hartmann, Rolf W.
Synthesis and Evaluation of Pyridylmethylene-tetrahydronaphthalenes and -indanes: Potent and Selective Inhibitors of Aldosterone Synthase (CYP11B2)
In: Journal of Medicinal Chemistry [48], 4489-4490
Ulmschneider, Sarah
Mueller-Vieira, Ursula
Mitrenga, Markus
Hartmann, Rolf W.
Oberwinkler-Marchais, S
Klein, Christian D.
Bureik, M.
Bernhardt, R.
Antes, Iris
Lengauer, Thomas
Synthesis and Evaluation of Imidazolylmethylenetetrahydronaphthalenes and Imidazolylmethyleneindanes: Potent Inhibitors of Aldosterone Synthase
In: Journal of Medicinal Chemistry [48], 1796-1805
Valentonyte, Ruta
Hampe, Jochen
Huse, Klaus
Rosenstiel, Philip
Albrecht, Mario
Stenzel, Annette
Nagy, Marion
Gaede, Karoline I.
Franke, Andre
Haesler, Robert
Koch, Andreas
Lengauer, Thomas
Seegert, Dirk
Reiling, Norbert
Ehlers, Stefan
Schwinger, Eberhard
Platzer, Mathias
Krawczak, Michael
Müller-Quernheim, Joachim
Schürmann, Manfred
Schreiber, Stefan
Sarcoidosis is associated with a truncating splice site mutation in BTNL2
In: Nature Genetics [37], 357-364
Van Duist, Marjan M.
Albrecht, Mario
Podswiadek, Marta
Giachino, Daniela
Lengauer, Thomas
Punzi, Leonardo
De Marchi, Mario
A new CARD15 mutation in Blau syndrome
In: European Journal of Human Genetics [13], 742-747
Voets, Marieke
Antes, Iris
Scherer, C
Mueller-Vieira, U.
Biemel, K.
Barrassin, C.
Marchais-Oberwinkler, S.
Hartmann, R. W.
Heteroaryl-substituted naphthalenes and structurally modified derivatives: selective inhibitors of CYP11B2 for the treatment of congestive heart failure and myocardial fibrosis
In: Journal of Medicinal Chemistry [48], 6632-6642
Wemmert, Silke
Ketter, Ralf
Rahnenführer, Jörg
Beerenwinkel, Niko
Strowitzki, Martin
Feiden, Wolfgang
Hartmann, Christian
Lengauer, Thomas
Stockhammer, Florian
Zang, Klaus D.
Meese, Eckart
Steudel, Wolf-Ingo
von Deimling, Andreas
Urbschat, Steffi
Attachment IconPatients with high grade gliomas harboring delections of chromosomes 9p and 10q benefit from temozolomide treatment
In: Neoplasia [7], 883-893
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