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MPI-INF D3 Publications

MPI-INF D3 Publications

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Author/Editor [Non Institute]YearTitleType
Adams, Altucci, Antonarakis, Ballesteros, Beck, Bird, Bock, Boehm, Campo, Caricasole, Dahl, Dermitzakis, Enver, Esteller, Estivill, Ferguson-Smith, Fitzgibbon, Flicek, Giehl, Graf, Grosveld, Guigó, Gut, Helin, Jarvius, Küppers, Lehrach, Lengauer, Lernmark, Leslie, Loeffler, Macintyre, Mai, Martens, Minucci, Ouwehand, Pelicci, Pendeville, Porse, Rakyan, Reik, Schrappe, Schübeler, Seifert, Siebert, Simmons, Soranzo, Spicuglia, Stratton, Stunnenberg, Tanay, Torrents, Valencia, Vellenga, Vingron, Walter, Willcocks
[-]
2012BLUEPRINT to decode the epigenetic signature written in blood
In: Nature Biotechnology [30], 224-226
Journal Article
Adams, McHardy, Lundegaard, Lengauer
(Ed: Frishman, Valencia)
[-]
2009Viral Bioinformatics
In: Modern Genome Annotation - The BioSapiens Network, 429-452
Part of a Book
Ahlenstiel, Roomp, Däumer, Nattermann, Vogel, Rockstroh, Beerenwinkel, Kaiser, Nischalke, Sauerbruch, Lengauer, Spengler
[-]
2007Attachment IconSelective pressures of HLA genotypes and antiviral therapy on human immunodeficiency virus type 1 sequence mutation at a population level
In: Clinical and Vaccine Immunology [14], 1266-1273
Journal Article
Albrecht
[-]
2010Color blindness
In: Nature Methods [7], 775
Journal Article
Albrecht
[-]
2006Combining protein structure prediction with experiments and functional information
Universität des Saarlandes
Thesis - PhD thesis
Albrecht
[-]
2005LRRK2 mutations and parkinsonism
In: The Lancet [365], 1230
Journal Article
Albrecht, Choubey, Lengauer
[-]
2005The HIN domain of IFI-200 proteins consists of two OB folds
In: Biochemical and Biophysical Research Communications [327], 679-687
Journal Article
Albrecht, Domingues, Schreiber, Lengauer
[-]
2003Identification of mammalian orthologs associates PYPAF5 with distinct functional roles
In: FEBS Letters [538], 173-177
Journal Article
Albrecht, Domingues, Schreiber, Lengauer
[-]
2003Structural localization of disease-associated sequence variations in the NACHT and LRR domains of PYPAF1 and NOD2
In: FEBS Letters [554], 520-528
Journal Article
Albrecht, Golatta, Wüllner, Lengauer
[-]
2004Structural and functional analysis of ataxin-2 and ataxin-3
In: European Journal of Biochemistry [271], 3155-3170
Journal Article
Albrecht, Hanisch, Zimmer, Lengauer
[-]
2002Attachment IconImproving fold recognition of protein threading by experimental distance constraints
In: In Silico Biology [2], 325-337
Journal Article
Albrecht, Hoffmann, Evert, Schmitt, Wüllner, Lengauer
[Hoffmann, Evert, Schmitt, Wüllner]
2003Structural modeling of ataxin-3 reveals distant homology to adaptins
In: Proteins: Structure, Function, and Genetics [50], 355-370
Journal Article
Albrecht, Huthmacher, Tosatto, Lengauer
[-]
2005Decomposing protein networks into domain-domain interactions
In: Bioinformatics [21], ii220-ii221
Journal Article
Albrecht, Kerren, Klein, Kohlbacher, Mutzel, Paul, Schreiber, Wybrow
(Ed: Eppstein, Gansner)
[-]
2010On open problems in biological network visualization
In: Graph Drawing : 17th International Symposium, GD 2009, 256-267
Proceedings Article
Albrecht, Lengauer
[-]
2004Novel Sm-like proteins with long C-terminal tails and associated methyltransferases
In: FEBS Letters [569], 18-26
Journal Article
Albrecht, Lengauer
[-]
2004Survey on the PABC recognition motif PAM2
In: Biochemical and Biophysical Research Communications [316], 129-138
Journal Article
Albrecht, Lengauer
[-]
2003Pyranose oxidase identified as a member of the GMC oxidoreductase family
In: Bioinformatics [19], 1216-1220
Journal Article
Albrecht, Lengauer, Schreiber
[-]
2003Disease-associated variants in PYPAF1 and NOD2 result in similar alterations of conserved sequence
In: Bioinformatics [19], 2171-2175
Journal Article
Albrecht, Takken
[-]
2006Update on the domain architectures of NLRs and R proteins
In: Biochemical and Biophysical Research Communications [339], 459-462
Journal Article
Albrecht, Tosatto, Lengauer, Valle
[Tosatto, Valle]
2003Simple consensus procedures are effective and sufficient in secondary structure prediction
In: Protein Engineering [16], 459-462
Journal Article
Alcaraz, Kucuk, Weile, Wipat, Baumbach
[-]
2012KeyPathwayMiner - Detecting case-specific biological pathways by using expression data
In: Internet Mathematics [7], 299-313
Journal Article
Alcaro, Alteri, Artese, Ceccherini-Silberstein, Costa, Ortuso, Forbici, Santoro, Parrotta, Flandre, Descamps, Calvez, Marcelin, Perno, Sing, Svicher
[-]
2011Docking Analysis and Resistance Evaluation of Clinically Relevant Mutations Associated with the HIV-1 Nonnucleoside Reverse Transcriptase Inhibitors Nevirapine, Efavirenz and Etravirine
In: ChemMedChem [6], 2203-2213
Journal Article
Alcaro, Artese, Ceccherini-Silberstein, Ortuso, Perno, Sing, Svicher
[-]
2009Molecular Dynamics and Free Energy Studies on the Wild-Type and Mutated HIV-1
Protease Complexed with Four Approved Drugs: Mechanism of Binding and
In: Journal of Chemical Information and Modeling [49], 1751-1761
Journal Article
Alexa
[-]
2005Integrating the GO graph structure in scoring the
significance of Gene Ontology terms
Universität des Saarlandes
Thesis - Masters thesis
Alexa, Rahnenführer, Lengauer
[-]
2006Attachment IconImproved Scoring of Functional Groups from Gene Expression Data by Decorrelating GO Graph Structure
In: Bioinformatics [22], 1600-1607
Journal Article
Altmann
[-]
2010Bioinformatical approaches to ranking of anti-HIV combination therapies and planning of treatment schedules
Universität des Saarlandes
Thesis - PhD thesis
Altmann, Beerenwinkel, Sing, Savenkov, Däumer, Kaiser, Rhee, Fessel, Shafer, Lengauer
[-]
2007Improved prediction of response to antiretroviral combination therapy using the genetic barrier to drug resistance
In: Antiviral Therapy [12], 169-178
Journal Article
Altmann, Däumer, Beerenwinkel, Peres, Schülter, Büch, Rhee, Sönnerborg, Fessel, Shafer, Zazzi, Kaiser, Lengauer
[-]
2009Predicting the Response to Combination Antiretroviral Therapy: Retrospective Validation of
geno2pheno-THEO on a Large Clinical Database
In: The Journal of Infectious Diseases [199], 999-1006
Journal Article
Altmann, Däumer, Sing, Beerenwinkel, Walter, Kaiser, Lengauer
[-]
2007Validation of geno2pheno and THEO on a large independent clinical dataset
In: Proceedings of the 5th European HIV Drug Resistance Workshop, -
Poster
Altmann, Pironti, Perner, Büch, Lengauer
(Ed: Schapiro, Boucher)
[-]
2010Determination of clinically relevant cutoffs for HIV-1 phenotypic resistance estimates through a combined analysis of clinical trial and cohort data
In: Abstract Book. 8th European Drug Resistance Workshop, 46
Poster
Altmann, Rosen-Zvi, Prosperi, Aharoni, Neuvirth, Schülter, Büch, Peres, Incardona, Sönnerborg, Kaiser, Zazzi, Lengauer
[-]
2008The EuResist approach for predicting response to anti HIV-1 therapy
In: Reviews in Antiviral Therapy, 107
Poster
Altmann, Rosen-Zvi, Prosperi, Aharoni, Neuvirth, Sönnerborg, Schülter, Büch, Struck, Peres, Incardona, Kaiser, Zazzi, Lengauer
[-]
2008Comparison of Classifier Fusion Methods for Predicting Response to Anti HIV-1 Therapy
In: PLoS ONE [3], e3470
Journal Article
Altmann, Sing, Vermeiren, Winters, Van Craenenbroeck, Van der Borght, Rhee, Shafer, Schülter, Kaiser, Peres, Sönnerborg, Fessel, Incardona, Zazzi, Bacheler, Van Vlijmen, Lengauer
[-]
2009Advantages of Predicted Phenotypes and Statistical Learning Models in Inferring Virological Response to Antiretroviral Therapy from HIV Genotype
In: Antiviral Therapy [14], 273-283
Journal Article
Altmann, Sing, Vermeiren, Winters, Van Craenenbroeck, Van der Borght, Rhee, Shafer, Schülter, Kaiser, Peres, Sonnerborg, Fessel, Incardona, Zazzi, Bacheler, Van Vlijmen, Lengauer
[-]
2007Inferring virological response from genotype: with or without predicted phenotypes?
In: Proceedings of the 16th International HIV Drug Resistance Workshop, S169
Poster
Altmann, Tolosi, Sander, Lengauer
[-]
2010Permutation importance: an unbiased feature importance measure
In: Bioinformatics [26], 1340-1347
Journal Article
Antes
[-]
2009Computational Methods for the Investigation of Protein-Ligand Interactions
Universität des Saarlandes
Thesis - Habilitation thesis
Antes, Chandler, Oster
[Oster]
2002A classical dynamics study of the unbinding of ATP from the F0F1-ATPase
In: Poster book of the European Conference on Computational Biology, Saarbrücken, Germany 2002, -
Poster
Antes, Klein
[-]
2001The formation of a β-Peptide/DPC-micelle complex studied by MD simulationsMiscellaneous
Antes, Lengauer
[-]
2006Refinement of homology modeled protein structures for molecular docking
In: Proceedings of the 367. WE-Heraeus Seminar on Biomolecular Simulations, 1
Poster
Antes, Lengauer, Mueller, Ulmschneider, Hartmann
[-]
2003Docking into the homology models of CYP11B1 and CYP11B2
In: Proceedings of the German Conference on Bioinformatics 2003, 13
Poster
Antes, Merkwirth, Lengauer
[-]
2005POEM: Parameter Optimization using Ensemble Methods: Application to target specific scoring functions
In: Journal of Chemical Information and Modeling [45], 1291-1302
Journal Article
Antes, Siu, Lengauer
[-]
2006Attachment IconDynaPred: A structure and sequence based method for the prediction of MHC class I binding peptide sequence and conformations
In: Bioinformatics [22], 16-24
Journal Article
Antes, Thiel, Gunsteren van
[-]
2002Molecular dynamics simulations of photoactive yellow protein (PYP) in three states of its photocycle: a comparison with X-ray and NMR data and analysis of the effects of Glu46 deprotonation and mutation
In: European Biophysics Jounal [31], 504-520
Journal Article
Antes, Wang, Chandler, Oster
[-]
2003The unbinding of ATP from F1-ATPase
In: Biophysical Journal [85], 695-706
Journal Article
Apostolakis, Hofmann, Lengauer
[Apostolakis, Hofmann]
2001Derivation of a scoring function for crystal structure prediction
In: Acta Crystallographica [A57], 442-450
Journal Article
Aranda, Blankenburg, Kerrien, Brinkman, Ceol, Chautard, Dana, De Las Rivas, Dumousseau, Galeota, Gaulton, Goll, Hancock, Isserlin, Jimenez, Kerssemakers, Khadake, Lynn, Michaut, O'Kelly, Ono, Orchard, Prieto, Razick, Rigina, Salwinski, Simonovic, Velankar, Winter, Wu, Bader, Cesareni, Donaldson, Eisenberg, Kleywegt, Overington, Ricard-Blum, Tyers, Albrecht, Hermjakob
[-]
2011PSICQUIC and PSISCORE: accessing and scoring molecular interactions
In: Nature Methods [8], 528-529
Journal Article
Assenov
[-]
2006Topological Analysis of Biological
Networks
Universität des Saarlandes
Thesis - Masters thesis
Assenov, Ramírez, Schelhorn, Lengauer, Albrecht
[-]
2008Computing topological parameters of biological networks
In: Bioinformatics [24], 282-284
Journal Article
Bader
[-]
2012Clustering epigenetic data using a Dirichlet process prior
Universität des Saarlandes
Thesis - Masters thesis
Balduin, Beerenwinkel, Sierra, Däumer, Rockstroh, Oette, Fätkenheuer, Kupfer, Hoffmann, Selbig, Pfister, Kaiser
[Balduin, Sierra, Däumer, Rockstroh, Oette, Fätkenheuer, Kupfer, Hoffmann, Selbig, Pfister, Kaiser]
2005Evolution of HIV resistance during treatment interruption in experienced patients and after restarting a new therapy
In: J Clin Virol [34], 277-287
Journal Article
Bastys
[-]
2012Attachment IconMAP Kinase Docking Motifs in HIV Proteins
Universität des Saarlandes
Thesis - Masters thesis
Baumbach
[-]
2012Integrative computational biology
In: Integrative Biology [4], 713-714
Journal Article
Baumbach
[-]
2010On the power and limits of evolutionary conservation - unraveling bacterial gene regulatory networks
In: Nucleic Acids Research [38], 7877-7884
Journal Article
Bayjanov
[-]
2004Scoring pathway activity from gene
expression data
Universität des Saarlandes
Thesis - Masters thesis
Beerenwinkel
(Ed: Oette, Kaiser, Häussinger)
[-]
2004Das Arevir-Projekt : neue Wege zur Optimierung von Anti-HIV-Therapien
In: Resistenz in der HIV-Therapie : Diagnostik und Management, 94-98
Part of a Book
Beerenwinkel
(Ed: Oette, Kaiser, Häussinger)
[-]
2004Methoden zur Interpretation genotypischer Resistenztests
In: Resistenz in der HIV-Therapie : Diagnostik und Management, 66-68
Part of a Book
Beerenwinkel
[-]
2004Computational Analysis of HIV Drug resistance DataBook
Beerenwinkel
[-]
2003Attachment IconComputational Analysis of HIV Drug Resistance Data
Universität des Saarlandes
Thesis - PhD thesis
Beerenwinkel, Däumer, Hoffmann, Kaiser, Korn, Lengauer, Schmidt, Walter, Selbig
[-]
2001Neue Wege zur Optimierung von Anti-HIV Therapien
In: BIOforum [24], 912-914
Journal Article
Beerenwinkel, Däumer, Hoffmann, Kaiser, Selbig, Lengauer
[-]
2003Bioinformatikmethoden für die Optimierung antiviraler Kombinationstherapien
In: MPG Jahrbuch, 481-486
Part of a Book
Beerenwinkel, Däumer, Kaiser, Walter, Korn, Hoffmann, Selbig, Lengauer
[Däumer, Kaiser, Walter, Korn, Hoffmann, Selbig]
2003Estimating effective drug combinations against drug-resistant mutants from genotypes
In: Proceedings of the 1st European HIV Drug Resistamce Workshop, 18-18
Proceedings Article
Beerenwinkel, Däumer, Oette, Korn, Hoffmann, Kaiser, Lengauer, Selbig, Walter
[-]
2003Geno2pheno: estimating phenotypic drug resistance from HIV-1 genotypes
In: Nucleic Acids Research [31], 3850-3855
Journal Article
Beerenwinkel, Däumer, Sing, Rahnenführer, Lengauer, Selbig, Hoffmann, Kaiser
[-]
2005Estimating HIV evolutionary pathways and the genetic barrier to drug resistance
In: The Journal of Infectious Diseases [191], 1953-1960
Journal Article
Beerenwinkel, Kaiser, Rahnenführer, Däumer, Hoffmann, Selbig, Lengauer
(Ed: Boucher, Mellors, Larder, Richman)
[-]
2003Tree models for the evolution of drug resistance
In: XII International HIV Drug resistance Workshop, S107-S107
Proceedings Article
Beerenwinkel, Lengauer, Däumer, Kaiser, Walter, Korn, Hoffmann, Selbig
[-]
2003Methods for optimizing antiviral combination therapies
In: Bioinformatics [19], i16-i25
Journal Article
Beerenwinkel, Lengauer, Däumer, Sierra, Schmidt, Walter, Korn, Oette, Fätkenheuer, Rockstroh, Hoffmann, Kaiser, Selbig
[-]
2002Geno2pheno is predictive of short-term virological response
In: Proceedings from the 5th International Workshop on HIV Drug Resistance & Treatment Strategies, 74-74
Proceedings Article
Beerenwinkel, Lengauer, Schmidt, Walter, Kaiser, Hoffmann, Korn, Selbig
[-]
2002Quantitative phenotype prediction by support vector machines
In: Proceedings from the 5th International Workshop on HIV Drug resistance & Treatment Strategies, 97
Proceedings Article
Beerenwinkel, Rahnenführer, Däumer, Hoffmann, Kaiser, Selbig, Lengauer
(Ed: Gusfield, Bourne, Istrail, Pevzner, Waterman)
[-]
2004Learning multiple evolutionary pathways from cross-sectional data
In: RECOMB 2004 : proceedings of the Eighth Annual International Conference on Research in Computational Molecular Biology, 36-44
Proceedings Article
Beerenwinkel, Rahnenführer, Däumer, Hoffmann, Kaiser, Selbig, Lengauer
[-]
2005Learning multiple evolutionary pathways from cross-sectional data
In: Journal of Computational Biology [12], 584-598
Journal Article
Beerenwinkel, Rahnenführer, Kaiser, Hoffmann, Selbig, Lengauer
[-]
2005Mtreemix: a software package for learning and using mixture models of mutagenetic trees
In: Bioinformatics [21], 2106-2107
Journal Article
Beerenwinkel, Schmidt, Walter, Kaiser, Lengauer, Hoffmann, Korn, Selbig
[-]
2002Diversity and complexity of HIV-1drug resistance: A bioinformatics approach to predicting phenotype from genotype
In: Proceedings of the National Academy of Sciences [99], 8271-8276
Journal Article
Beerenwinkel, Schmidt, Walter, Kaiser, Lengauer, Hoffmann, Korn, Selbig
[Schmidt, Walter, Kaiser, Hoffmann, Korn, Selbig]
2001Geno2pheno: A system for the interpretation of genotypic HIV Drug resistance tests
In: IEEE Intelligent Systems [16], 35-41
Journal Article
Beerenwinkel, Sing, Däumer, Kaiser, Lengauer
(Ed: Boucher, Mellors, Larder, Richman)
[-]
2004Computing the genetic barrier
In: XII International HIV Drug resistance Workshop, S125-S125
Proceedings Article
Beerenwinkel, Sing, Lengauer, Rahnenführer, Roomp, Savenkov, Fischer, Hoffmann, Selbig, Korn, Walter, Berg, Braun, Fätkenheuer, Oette, Rockstroh, Kupfer, Kaiser, Däumer
[-]
2005Computational methods for the design of effective therapies against drug resistant HIV strains
In: Bioinformatics [21], 3943-3950
Journal Article
Beggel, Lengauer
[-]
2013Inferring short-range linkage information from sequencing chromatograms
In: PLoS One,
Electronic Journal Article
Beggel, Münk, Däumer, Hauck, Häussinger, Lengauer, Ehrhardt
[-]
2013Full genome ultra-deep pyrosequencing associates G-to-A-hypermutation of the hepatitis B virus genome with the natural progression of hepatitis B
In: Journal of Viral Hepatitis [12], 882-889
Journal Article
Beggel, Neumann-Fraune, Doering, Lawyer, Kaiser, Verheyen, Lengauer
[-]
2012Genotyping hepatitis B virus dual infections using population-based sequence data
In: Journal of General Virology [9], 1899-1907
Journal Article
Bhadra, Battacharya, Feuerbach, Lengauer, Bandyopadhyay
[-]
2013DNA Methylation Patterns Facilitate the Identification of Transcription Start Sites: A Brain-specofoc Study
In: PLOSONE [8], xx
Journal Article
Bhattacharyya, Feuerbach, Bhadra, Bandyopadhyay
[-]
2012MicroRNA Transcription Start Site Prediction with Multi-objective Feature Selection
In: Statistical Applications in Genetics and Molecular Biology [11], 6.1-6.25
Journal Article
Bickel, Bogojeska, Lengauer, Sheffer
(Ed: McCallum, Roweis)
[-]
2008Attachment IconMulti-Task Learning for HIV Therapy Screening
In: Proceedings, Twenty-Fifth International Conference on Machine Learning, 56-63
Proceedings Article
Binsl
[-]
2006Feature Prints: A new method for calculating molecular similarities
Universität des Saarlandes
Thesis - Masters thesis
Binsl
[-]
2004Attachment IconImplementation of a Generic Fragment
Based Method for Automated
Calculation of the Octanol-Water
Partition Coefficient
Universität des Saarlandes
Thesis - Bachelor thesis
Blankenburg
[-]
2007A Distributed Annotation System for Molecular Interactions
Ruprecht Karl Universität Heidelberg; Universität Heilbronn
Thesis - other
Blankenburg, Finn, Prlić, Jenkinson, Ramírez, Emig, Schelhorn, Büch, Lengauer, Albrecht
[-]
2009DASMI: exchanging, annotating and assessing molecular interaction data
In: Bioinformatics [25], 1321-1328
Journal Article
Blankenburg, Ramírez, Büch, Albrecht
[-]
2009DASMIweb: online integration, analysis and assessment of distributed protein interaction data
In: Nucleic Acids Research [37], W122-W128
Electronic Journal Article
Bleif, Hannemann, Lisurek, von Kries, Zapp, Dietzen, Antes, Bernhardt
[-]
2011Identification of CYP106A2 as a Regioselective Allylic Bacterial Diterpene Hydroxylase
In: ChemBioChem [12], 576-582
Journal Article
Bock
[-]
2012Analysing and interpreting DNA methylation data
In: Nature Reviews Genetics [13], 705-719
Journal Article
Bock
[-]
2009Attachment IconEpigenetic biomarker development
In: Epigenomics [1], 99-110
Journal Article
Bock
[-]
2008Computational Epigenetics - Bioinformatic methods for epigenome prediction, DNA methylation mapping and cancer epigenetics
Universität des Saarlandes
Thesis - PhD thesis
Bock
[-]
2008IVF: stars may have to consider the risk of stolen parenthood
In: Nature [454], 938
Journal Article
Bock
[-]
2006Bioinformatik: Neue Strategien gegen Krebs
In: Deutsches Ärzteblatt PRAXiS [103], 10-11
Journal Article
Bock, Halachev, Büch, Lengauer
[-]
2009Attachment IconEpiGRAPH: user-friendly software for statistical analysis and prediction of (epi)genomic data
In: Genome Biology [10], R14.1-R14.14
Journal Article
Bock, Halachev, Lengauer
(Ed: Haasis, Heinzl, Klumpp)
[-]
2006Bioinformatisches Data Mining erschließt neue Strategien gegen Krebs
In: Aktuelle Trends in der Softwareforschung, 91-99
Part of a Book
Bock, Hesser
[-]
2006Attachment IconAnalysis and Prediction of Helix Shift Errors in Homology Modeling
In: In Silico Biology [6], 131-145
Journal Article
Bock, Kiskinis, Verstappen, Gu, Boulting, Smith, Ziller, Croft, Amoroso, Oakley, Gnirke, Eggan, Meissner
[-]
2011Reference Maps of Human ES and iPS Cell Variation Enable High-Throughput Characterization of Pluripotent Cell Lines
In: Cell [144], 439-452
Journal Article
Bock, Lengauer
[-]
2012Epigenom-Karten erstellen und nutzen
In: BIOspektrum [18], 138-141
Journal Article
Bock, Lengauer
[-]
2012Managing drug resistance in cancer: lessons from HIV therapy
In: Nature Reviews Cancer [12], 494-501
Journal Article
Bock, Lengauer
[-]
2008Attachment IconComputational epigenetics
In: Bioinformatics [24], 1-10
Journal Article
Bock, Lengauer
[-]
2007Attachment IconComputational Epigenetics: Bioinformatik für neue Wege in der Krebsforschung
In: Jahrbuch 2007, 271-277
Part of a Book
Bock, Lengauer, Reither, Mikeska, Paulsen, Walter
[-]
2005Attachment IconBiQ Analyzer: visualization and quality control for DNA methylation data from bisulfite sequencing
In: Bioinformatics [21], 4067-4068
Journal Article
Bock, Paulsen, Tierling, Mikeska, Lengauer, Walter
[-]
2006Attachment IconCpG Island Methylation in Human Lymphocytes Is Highly Correlated with DNA Sequence, Repeats, and Predicted DNA Structure
In: PLoS Genetics [2], 0243-0252
Electronic Journal Article
Bock, Tomazou, Brinkman, Müller, Simmer, Gu, Jäger, Gnirke, Stunnenberg, Meissner
[-]
2010Attachment IconQuantitative comparison of genome-wide DNA methylation mapping technologies
In: Nature Biotechnology [28], 1106-1114
Journal Article
Bock, Von Kuster, Halachev, Taylor, Nekrutenko, Lengauer
(Ed: Barnes, Breen)
[-]
2010Web-based analysis of (epi-) genome data using EpiGRAPH and Galaxy.
In: Genetic Variation : Methods and Protocols, 275-296
In: Methods of Molecular Biology [628], 275-296
Part of a Book
Bock, Walter, Paulsen, Lengauer
[-]
2008Attachment IconInter-individual variation of DNA methylation and its implications for large-scale epigenome mapping
In: Nucleic Acids Research [36], e55
Journal Article
Bock, Walter, Paulsen, Lengauer
[-]
2007Attachment IconCpG Island Mapping by Epigenome Prediction
In: PLoS Computational Biology [3], 1055-1070
Journal Article
Boeddrich, Gaumer, Haacke, Tzvetkov, Albrecht, Evert, Müller, Lurz, Breuer, Schugardt, Plaßmann, Xu, Warrick, Suopanki, Wüllner, Frank, Hartl, Bonini, Wanker
[-]
2006An arginine/lysine-rich motif is crucial for VCP/p97-mediated modulation of ataxin-3 fibrillogenesis
In: EMBO Journal [25], 1547-1558
Journal Article
Bogojeska
(Ed: Shawe-Taylor, Zemel, Bartlett, Pereira, Weinberger)
[-]
2011History distribution matching method for predicting effectiveness of HIV combination therapies
In: Neural Information Processing Systems (NIPS 2011), 424-432
Electronic Proceedings Article
Bogojeska
[-]
2011Attachment IconStatistical Learning Methods for Bias-aware HIV Therapy Screening
Universität des Saarlandes
Thesis - PhD thesis
Bogojeska
[-]
2007Stability analysis of oncogenetic trees mixture models
Universität des Saarlandes
Thesis - Masters thesis
Bogojeska, Alexa, Altmann, Lengauer, Rahnenführer
[-]
2008Attachment IconRtreemix: an R package for estimating evolutionary pathways and genetic progression scores
In: Bioinformatics [24], 2391-2392
Journal Article
Bogojeska, Bickel, Altmann, Lengauer
[-]
2010Attachment IconDealing with sparse data in predicting outcomes of HIV combination therapies
In: Bioinformatics [26], 2085-2092
Journal Article
Bogojeska, Lengauer
[-]
2012Hierarchical Bayes Model for Predicting Effectiveness of HIV Combination Therapies
In: Statistical Applications in Genetics and Molecular Biology [11], 11.1-11.19
Journal Article
Bogojeska, Lengauer, Rahnenführer
[-]
2008Stability analysis of mixtures of mutagenetic trees
In: BMC Bioinformatics [9], 165-181
Journal Article
Bogojeska, Stöckel, Zazzi, Kaiser, Incardona, Rosen-Zvi, Lengauer
(Ed: Lawrence, Girolami)
[-]
2012History-alignment models for bias-aware prediction of virological response to HIV combination therapy
In: Proceedings of the Fifteenth International Conference on Artificial Intelligence and Statistics (AISTATS 2012), 118-126
Proceedings Article
Bojunga, Welsch, Antes, Albrecht, Lengauer, Zeuzem
[-]
2005Structural and functional analysis of a novel mutation of CYP21B in a heterozygote carrier of 21-hydroxylase deficiency
In: Human Genetics [117], 558-564
Journal Article
Bozek
[-]
2011Attachment IconAnalysis of HIV-host interaction on different scales.
Universität des Saarlandes
Thesis - PhD thesis
Bozek, Eckhardt, Sierra, Kaiser, Kräusslich, Müller, Lengauer
[-]
2012An expanded model of HIV cell entry phenotype based on multi-parameter single-cell data
In: Retrovirology [9], 60.1-60.15
Journal Article
Bozek, Lengauer
[-]
2010Positive selection of HIV host factors and the evolution of lentivirus genes
In: BMC Evolutionary Biology [10], 186,1-186,15
Electronic Journal Article
Bozek, Lengauer, Sierra, Kaiser, Domingues
[-]
2013Analysis of physicochemical and structural properties determining HIV-1 coreceptor usage
In: PLoS Computational Biology [x], x
Journal Article
Bozek, Relógio, Kielbasa, Heine, Dame, Kramer, Herzel
[-]
2009Regulation of clock-controlled genes in mammals.
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2010Circadian transcription in liver
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2009V3 loop sequence space analysis suggests different evolutionary patterns of CCR5- and CXCR4-tropic HIV.
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2002Automated Grid Alignment for High-Throughput Analysis of Microarray Images (CIIST-02)
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[Brooks-Wilson, Marcil, Clee, Zhang, van Dam, Yu, Brewer, Collins, Molhuizen, Loubser, Ouelette, Fichter, Ashbourne-Excoffon, Sensen, Scherer, Mott, Denis, Martindale, Frohlich, Morgan, Koop, Pimstone, Kastelein, Hayden]
1999Mutations in ABC1 in Tangier disease and familial high-density lipoprotein
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2010Intragenic allele pyramiding combines different specificities of wheat Pm3 resistance alleles
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Calvanese, Fernandez, Urdinguio, Suarez-Álvarez, Mangas, Pérez-García, Bueno, Montes, Ramos-Mejía, Martínez-Camblor, Ferrero, Assenov, Bock, Menendez, Carrera, Lopez-Larrea, Fraga
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2012A promoter DNA demethylation landscape of human hematopoietic differentiation
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Castellano, Lobanov, Chapple, Novoselov, Albrecht, Hua, Lescure, Lengauer, Krol, Gladyshev, Guigó
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2005Diversity and functional plasticity of eukaryotic selenoproteins: Identification and characterization of the SelJ family
In: Proceedings of the National Academy of Sciences [102], 16188-16193
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Ceccherini-Silberstein, Svicher, Sing, Artese, Santoro, Forbici, Bertoli, Alcaro, Palamara, Monforte, Balzarini, Antinori, Lengauer, Perno
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2007Attachment IconCharacterization and structural analysis of novel mutations in human immunodeficiency virus type 1 reverse transcriptase involved in the regulation of restistance to nonnucleoside inhibitors
In: Journal of Virology [81], 11507-11519
Journal Article
Cerdeira, Carneir, Ramos, de Almeida, D'Afonseca, Schneider, Baumbach, Tauch, McCulloch, Azevedo, Silva
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2011Rapid hybrid de novo assembly of a microbial genome using only short reads: Corynebacterium pseudotuberculosis I19 as a case study
In: Journal of Microbiological Methods [86], 218-223
Journal Article
Claussen, Buning, Rarey, Lengauer
[Claußen, Buning, Rarey]
2001FlexE: Efficient Molecular Docking Considering Protein Structure Variations
In: Journal of Molecular Biology [308], 377-395
Journal Article
Clee, Kastelein, van Dam, Marcil, Roomp, Zwarts, Collins, Roelants, Tamasawa, Stulc, Suda, Ceska, Boucher, Rondeau, DeSouich, Brooks-Wilson, Molhuizen, Frohlich, Genest, Hayden
[Clee, Kastelein, van Dam, Marcil, Zwarts, Collins, Roelants, Tamasawa, Stulc, Suda, Ceska, Boucher, Rondeau, DeSouich, Brooks-Wilson, Molhuizen, Frohlich, Genest, Hayden]
2000Age and residual cholesterol efflux affect HDL cholesterol levels and coronary artery disease in ABCA1 heterozygotes
In: Journal of Clinical Investigation [106], 1263-70
Journal Article
Clee, Zwinderman, Engert, Zwarts, Molhuizen, Roomp, Jukema, van Wijland, van Dam, Hudson, Brooks-Wilson, Genest, Kastelein, Hayden
[Clee, Zwinderman, Engert, Zwarts, Molhuizen, Jukema, van Wijland, van Dam, Hudson, Brooks-Wilson, Genest, Kastelein, Hayden]
2001Common genetic variation in ABCA1 is associated with altered lipoprotein levels and a modified risk for coronary artery disease
In: Circulation [103], 1198-205
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Codoner, Pou, Thielen, García, Delgado, Dalmau, Álvarez-Tejado, Ruiz, Clotet, Paredes
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2011Added value of deep sequencing relative to population sequencing in heavily pre-treated HIV-1-infected subjects
In: PLoS One [6], e19461,1-e19461,5
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Codoñer, Pou, Thielen, García, Delgado, Dalmau, Santos, Buzón, Martínez-Picado, Clotet, Ruiz, Paredes
[-]
2010Dynamic escape of pre-existing raltegravir-resistant HIV-1 from raltegravir selection pressure
In: Antiviral Research [88], 281-286
Journal Article
Costello, Mah, Häsler, Rosenstiel, Waetzig, Hahn, Lu, Gurbuz, Nikolaus, Albrecht, Hampe, Lucius, Klöppel, Eickhoff, Lehrach, Lengauer, Schreiber
[-]
2005Dissection of the inflammatory bowel disease transcriptome using genome-wide cDNA microarrays identifies novel candidate disease genes
In: PLoS Medicine [2], 771-787
Journal Article
Crass, Antes, Basekow, Bork, Buning, Christensen, Claußen, Ebeling, Ernst, Gailus-Durner, Glatting, Gohla, Gößling, Grote, Heidtke, Herrmann, O Keefe, Kießlich, Kolibal, Korbel, Lengauer, Liebich, van der Linden, Luz, Meissner, von Mering, Mevissen, Mewes, Michael, Mokrejs, Müller, Pospisil, Rarey, Reich, Schneider, Schomburg, Schulze-Kremer, Schwarzer, Sommer, Springstubbe, Suhai, Thoppae, Vingron, Warfsmann, Werner, Wetzler, Wingender, Zimmer
[-]
2004The Helmholtz Network for Bioinformatics: an integrative web portal for bioinformatics resources
In: Bioinformatics [20], 268-270
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Däumer, Awerkiew, Sierra Aragon, Kartashev, Poplavskaja, Klein, Sichtig, Thielen, Lengauer, Roomp, Pfister, Kaiser
[-]
2010Short Communication: Selection of Thymidine Analogue Resitance Mutational Patterns in Children from a Common HIV Type 1 Subtype G Source
In: AIDS Research and Human Retroviruses [26], 275-278
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Däumer, Kaiser, Klein, Lengauer, Thiele, Thielen
[-]
2011Genotypic tropism testing by massively parallel sequencing: qualitative and quantitative analysis
In: BMC Medical Informatics and Decision Making [11], 30,1-30,8
Electronic Journal Article
Däumer, Kaiser, Klein, Lengauer, Thiele, Thielen
[-]
2008Inferring viral tropism from genotype with massively parallel sequencing; qualitative and quantitative analysis
In: Antiviral Therapy, A101
Poster
Das, James, Rahnenführer, Thoresona, Bhattacharyaa, Zhao, Ahmad
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2005Retinal properties and potential of the adult mammalian ciliary epithelium stem cells
In: Vision Research [45], 1653-1666
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Diehl
[-]
2009Analysis and reconstruction of protein complex topology
Universität des Saarlandes
Thesis - Masters thesis
Dietzen
[-]
2007An additive tree-based approach to the prediction of the strength of acidity for drug-like molecules
Universität des Saarlandes
Thesis - Masters thesis
Dietzen, Zotenko, Hildebrandt, Lengauer
[-]
2012On the Applicability of Elastic Network Normal Modes in Small-Molecule Docking
In: Journal of Chemical Information and Modeling [52], 844-856
Journal Article
Dietz, Schelhorn, Fitting, Mihm, Susser, Welker, Füller, Däumer, Teuber, Wedemeyer, Berg, Lengauer, Z., Herrmann, Sarrazin
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2013Deep sequencing reveals mutagenic effects of ribavirin during monotherapy of HCV genotype 1-infected patients
In: Journal of Virology [87], 6172-6181
Journal Article
Djoumbou
[-]
2008Molecular Dynamics based prediction of HIV-1 drug resistance
Universität des Saarlandes
Thesis - Masters thesis
Djoumbou
[-]
2005Docking studies to investigate the effect of correlated mutations in the HIV-Protease on the drug resistance of HIV
Universität des Saarlandes
Thesis - Bachelor thesis
Döring
[-]
2011Web Implementation of the HBV Dual Infection Model
Universität des Saarlandes
Thesis - Bachelor thesis
Dörr
[-]
2010Using copy number variation fpr predicting susceptibility to glioblastoma
Universität des Saarlandes
Thesis - Bachelor thesis
Domingues, Lengauer
(Ed: Lengauer)
[-]
2007Inferring Protein Function from Protein Structure
In: Bioinformatics - From Genomes to Therapies 3. The Holy Grail: Molecular Function, 1211-1252
Part of a Book
Domingues, Lengauer
[-]
2003Protein Function from Sequence and Structure Data
In: Applied Bioinformatics [2], 3-12
Journal Article
Domingues, Lengauer, Sommer
(Ed: Cooper)
[-]
2004Protein Structure Prediction and Databases
In: Nature Encyclopedia of the Human Genome, 864-867
Part of a Book
Domingues, Rahnenführer, Lengauer
[-]
2007Conformational analysis of alternative protein structures
In: Bioinformatics [23], 3131-3138
Journal Article
Domingues, Rahnenführer, Lengauer
[-]
2004Automated clustering of ensembles of alternative models in protein structure databases
In: Protein Engineering Design and Selection [17], 537-543
Journal Article
Doncheva
[-]
2009Analysis and visualization of residue interaction networks
Universität des Saarlandes
Thesis - Masters thesis
Doncheva, Assenov, Domingues, Albrecht
[-]
2012Topological analysis and interactive visualization of biological networks and protein structures
In: Nature Protocols [7], 670-685
Journal Article
Doncheva, Kacprowski, Albrecht
[-]
2012Recent approaches to the prioritization of candidate disease genes
In: Wiley Interdisciplinary Reviews: Systems Biology and Medicine [4], 429-442
Journal Article
Doncheva, Klein, Domingues, Albrecht
[-]
2011Analyzing and visualizing residue networks of protein structures
In: Trends in Biochemical Sciences [36], 179-182
Journal Article
Ebert
[-]
2009Computational Analysis of genomic HPV data
Universität des Saarlandes
Thesis - Bachelor thesis
Ebrahimi, Lakizadeh, Agha-Golzadeh, Ebrahimi
[-]
2011Prediction of Thermostability from Amino Acid Attributes by Combination of Clustering with Attribute Weighting: A New Vista in Engineering Enzymes
In: PLoS One [6], e23146,1-e23146,11
Electronic Journal Article
Eckel, Baumbach, Hauschild
[-]
2014On the importance of statistics in breath analysis - Hope or curse?Unpublished/Draft
Eldarov
[-]
2012Modeling influenza evolution in response to immune system pressure
Universität des Saarlandes
Thesis - Masters thesis
Ellinghaus, Ellinghaus, Stuart, Nair, Debrus, Raelson, Belouchi, Fournier, Reinhard, Ding, Li, Tejasvi, Gudjonsson, Stoll, Voorhees, Lambert, Weidinger, Eberlein, Kunz, Rahman, Gladman, Gieger, Wichmann, Karlsen, Mayr, Albrecht, Kabelitz, Mrowietz, Abecasis, Elder, Schreiber, Weichenthal, Franke
[-]
2010Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2
In: Nature Genetics [42], 991-995
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Ellinghaus, Zhang, Zeissig, Lipinski, Till, Jiang, Stade, Bromberg, Ellinghaus, Keller, Rivas, Skieceviciene, Doncheva, Liu, Liu, Jiang, Forster, Mayr, Albrecht, Häsler, Boehm, Goodall, Berzuini, Lee, Andersen, Vogel, Kupcinskas, Kayser, Krawczak, Nikolaus, Weersma, Ponsioen, Sans, Wijmenga, Strachan, McArdle, Vermeire, Rutgeerts, Sanderson, Mathew, Vatn, Wang, Nöthen, Duerr, Büning, Brand, Glas, Winkelmann, Illig, Latiano, Annese, Halfvarson, D'Amato, Daly, Nothnagel, Karlsen, Subramani, Rosenstiel, Schreiber, Parkes, Franke
[-]
2013Association between variants of PRDM1 and NDP52 and Crohn's disease, based on exome sequencing and functional studies
In: Gastroenterology [145], 339-347
Journal Article
Emig
[-]
2011Novel analysis approaches to context-dependent molecular networks
Universität des Saarlandes
Thesis - PhD thesis
Emig
[-]
2007The Impact of Alternative Splicing on Protein Interaction Networks
Eberhard Karls Universität Tübingen
Thesis - other
Emig, Albrecht
[-]
2011Tissue-specific proteins and functional implications
In: Journal of Proteome Research [10], 1893-1903
Journal Article
Emig, Blankenburg, Ramírez, Albrecht
(Ed: Larson)
[-]
2012Functional characterization of human genes from exon expression and RNA interference results
In: Bioinformatics and Drug Discovery, 33-53
Part of a Book
Emig, Cline, Klein, Kunert, Mutzel, Lengauer, Albrecht
[-]
2008Integrative visual analysis of the effects of alternative splicing on protein domain interaction networks
In: Journal of Integrative Bioinformatics [5], 101-115
Journal Article
Emig, Cline, Lengauer, Albrecht
[-]
2008Integrating expression data with domain interaction networks
In: Bioinformatics [24], 2546-2548
Journal Article
Emig, Kacprowski, Albrecht
(Ed: Nykter, Ruusuvuori, Carlberg, Yli-Harja)
[-]
2010Measuring and analyzing tissue specificity of human genes and protein complexes
In: Seventh International Workshop on Computational Systems
Biology, WCSB 2010, 27-30
Proceedings Article
Emig, Kacprowski, Albrecht
[-]
2011Measuring and analyzing tissue specificity of human genes and protein complexes
In: EURASIP Journal on Bioinformatics and Systems Biology [2011], 5,1-5,6
Journal Article
Emig, Klein, Kunert, Mutzel, Albrecht
[-]
2008Visualizing domain interaction networks and the impact of alternative splicing events
In: Proceedings of the 5th International Conference on BioMedical Visualization (MediVis): Information Visualization in Medical and Biomedical Informatics, 36-43
Proceedings Article
Emig, Salomonis, Baumbach, Lengauer, Conklin, Albrecht
[-]
2010AltAnalyze and DomainGraph: analyzing and visualizing exon expression data
In: Nucleic Acids Research [38], W755-W762
Journal Article
Emig, Sander, Mayr, Albrecht
[-]
2011Structure collisions between interacting proteins
In: PLoS ONE [6], e19581,1-e19581,7
Electronic Journal Article
Eyrisch
[-]
2004Attachment IconFun2Struc-A Tool For Predicting Protein Structure
Classes from Function Predictions
Universität des Saarlandes
Thesis - Bachelor thesis
Faria, Schlicker, Pesquita, Bastos, Ferreira, Albrecht, Falcão
[-]
2012Mining GO annotations for improving annotation consistency
In: PLoS ONE [7], e40519,1-e40519,7
Electronic Journal Article
Fernandez, Assenov, Martin-Subero, Balint, Siebert, Taniguchi, Yamamoto, Hidalgo, Tan, Galm, Ferrer, Sanchez-Cespedes, Villanueva, Carmona, Sanchez-Mut, Berdasco, Moreno, Capella, Monk, Ballestar, Ropero, Martinez, Sanchez-Carbayo, Prosper, Agirre, Fraga, Gran˜a, Perez-Jurado, Mora, Puig, Prat, Badimon, Puca, Meltzer, Lengauer, Bridgewater, Bock, Esteller
[-]
2012A DNA methylation fingerprint of 1628 human samples
In: Genome Research [22], 407-419
Journal Article
Feuerbach
[-]
2007Attachment IconTowards Comparative Epigenomics: A Pilot Study on DNA Methylation of CpG Islands on Human Chromosome 21
Universität des Saarlandes
Thesis - Masters thesis
Feuerbach, Christopher, Halachev, Büch, Lengauer
(Ed: Meijer, Ried, Giaretti, Hamilton)
[-]
2008Towards Comparative Epigenomics: A Software Toolkit For Cross-Species Epigenome Data Analysis
In: Abstracts of the 2nd MC-GARD Meeting, 230
Electronic Proceedings Article
Feuerbach, Halachev, Assenov, Mueller, Bock, Lengauer
(Ed: Anisimova)
[-]
2012Analyzing epigenome data in context of genome evolution and human diseases
In: Evolutionary Genomics : Statistical and Computational Methods, Volume 2, 431-467
In: Methods of Molecular Biology [856], 431-467
Part of a Book
Feuerbach, Halachev, Lengauer, Bock
(Ed: Meijer, Ried, Giaretti, Hamilton)
[-]
2009An exhaustive methode for CpG island annotation
In: Special Issue: Abstracts of the 3rd MC-GARD Meeting, 146-146
Poster
Feuerbach, Lengauer
[-]
2010Ancestral germline methylation reconstruction of young repeats
In: Transcription, chromatin structure and DNA repair in development and differentiation, 81
Poster
Feuerbach, Lyngsoe, Lengauer, Hein
[-]
2010Comparative Epigenomiocs - Towards Ancestral Germline Methylome Reconstruction
In: Abstracts of papers presented at the 2010 meeting on The Biology of genomes, 87
Poster
Feuerbach, Lyngso, Lengauer, Hein
[-]
2011Reconstructing the ancestral germline methylation state of young repeats
In: Molecular Biology and Evolution [28], 1777-1784
Journal Article
Fischer
[-]
2008Structure-based prediction of HIV-1 drug resistance
Universität des Saarlandes
Thesis - Masters thesis
Flockerzi, Maydt, Frank, Ruggieri, Maldener, Seifarth, Medstrand, Lengauer, Meyerhans, Leib-Mosch, Meese, Mayer
[-]
2007Attachment IconExpression pattern analysis of transcribed HERV sequences is complicated by ex vitvo recombination
In: Retrovirology [4], 39
Journal Article
Franke, Balschun, Karlsen, Sventoraityte, Nikolaus, Mayr, Domingues, Albrecht, Nothnagel, Ellinghaus, Sina, Onnie, Weersma, Stokkers, Wijmenga, Gazouli, Strachan, McArdle, Vermeire, Rutgeers, Rosenstiel, Krawczak, Vatn, IBSEN study group, Mathew, Schreiber
[-]
2008Sequence variants in IL10, ARPC2, and multiple other loci contribute to ulcerative colitis
In: Nature Genetics [40], 1319-1323
Journal Article
Franke, Balschun, Sina, Ellinghaus, Häsler, Mayr, Albrecht, Wittig, Buchert, Nikolaus, Gieger, Wichmann, Sventoraityte, Kupcinskas, Onnie, Gazouli, Anagnou, Strachan, McArdle, Mathew, Rutgeerts, Vermeire, Vatn, Krawczak, Rosenstiel, Karlsen, Schreiber
[-]
2010Genome-wide association study for ulcerative colitis identifies risk loci at 7q22 and 22q13 (IL17REL)
In: Nature Genetics [42], 292-294
Journal Article
Franke, Hampe, Rosenstiel, Becker, Wagner, Häsler, Little, Huse, Ruether, Balschun, Wittig, ElSharawy, Mayr, Albrecht, Prescott, Onnie, Fournier, Keith, Radelof, Platzer, Mathew, Stoll, Krawczak, Nürnberg, Schreiber
[-]
2007Systematic association mapping identifies NELL1 as a novel IBD disease gene
In: PLoS ONE [2], e691.1-13
Journal Article
Freudenberg, Zimmer, Hanisch, Lengauer
[-]
2002A hypergraph-based method for unification of existing protein structure- and sequence-families
In: In Silico Biology [2], 339 - 349
Journal Article
Frings
[-]
2006Development of a
Smith-Waterman-Like Multi-Aspect
Alignment Tool
Universität des Saarlandes
Thesis - Bachelor thesis
Frishman, Albrecht, Blankenburg, Bork, Harrington, Hermjakob, Jensen, Juan, Lengauer, Pagel, Schachter, Valencia
(Ed: Frishman, Valencia)
[-]
2009Protein-protein interactions: analysis and prediction
In: Modern Genome Annotation - The Biosapiens Network, 353-410
Part of a Book
Galata
[-]
2012Applying Lasso regression to related cell types for gene network astimation
Universität des Saarlandes
Thesis - Bachelor thesis
Garai, Zeke, Gógl, Töro, Fördos, Blankenburg, Bárkai, Varga, Alexa, Emig, Albrecht, Reményi
[-]
2012Specificity of linear motifs that bind to a common mitogen-activated protein kinase docking groove
In: Science Signaling [5], ra74,1-ra74,14
Journal Article
Gatzmann
[-]
2010GOdot Sequence - function prediction from protein sequence
Universität des Saarlandes
Thesis - Bachelor thesis
Glaab
[-]
2006On the predictability of CpG methylation in human tissue at single basepair resolution
Universität des Saarlandes
Thesis - Bachelor thesis
Guo
[-]
2006Improving Fold Recognition Using Protein
and Domain Interactions
Universität des Saarlandes
Thesis - Masters thesis
Gu, Bock, Mikkelsen, Jäger, Smith, Tomazou, Gnirke, Lander, Meissner
[-]
2010Attachment IconGenome-scale DNA methylation mapping of clinical samples at single-nucleotide resolution
In: Nature Methods [7], 133-136
Journal Article
Gu, Kofler, Antes, Freund, Helms
[-]
2005Alternative Binding Modes of Polyproline Peptides Binding to the GYF Domain
In: Biochemistry [44], 6404-6415
Journal Article
Gu, Smith, Bock, Boyle, Gnirke, Meissner
[-]
2011Preparation of reduced representation bisulfite sequencing libraries for genome-scale DNA methylation profiling
In: Nature Protocols [6], 468-481
Journal Article
Gwinner
[-]
2009Assessing the Conservation of Protein Function on Evolutionary Defined Patches
Universität des Saarlandes
Thesis - Masters thesis
Hahn, Costello, Lu, Lengauer, Schreiber
[-]
2004Expression analysis for inflammatory bowel disease
In: Workshop Poster Competition, ?
Poster
Hahn, Costello, Lu, Lengauer, Schreiber
[-]
2002Attachment IconExpression analysis for inflammatory bowel disease
In: Proceedings of the n?th Conference on, ?
Poster
Hahn, Rahnenführer, Talwar, Lengauer
[-]
2005Confirmation of human protein interaction data by human expression data
In: BMC Bioinformatics [6], 1-11
Journal Article
Haid
[-]
2007BSIFlex: Binding Site Identification including protein flexibility
Universität des Saarlandes
Thesis - Masters thesis
Halachev
[-]
2006EpiGRAPHregression: A toolkit for (epi-)genomic correlation analysis and prediction of quantitative attributes
Universität des Saarlandes
Thesis - Masters thesis
Halachev, Bast, Albrecht, Lengauer, Bock
[-]
2012Attachment IconEpiExplorer: live exploration and global analysis of large epigenomic datasets
In: Genome Biology [13], R96,1-R96,14
Electronic Journal Article
Halachev, Bast, Albrecht, Lengauer, Bock
[-]
2012EpiExplorer: live exploration and global analysis of large epigenomic datasets
In: Genome Biology [13], R96,1-R96,14
Journal Article
Halachev, Bast, Lengauer, Bock
[-]
2013Interactive exploration of large genome and epigenome datasets in real time
In: Genome Biology [13], xx
Journal Article
Hampe, Franke, Rosenstiel, Till, Teuber, Huse, Albrecht, Mayr, De La Vega, Briggs, Günther, Prescott, Onnie, Häsler, Sipos, Fölsch, Lengauer, Platzer, Mathew, Krawczak, Schreiber
[-]
2007A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1
In: Nature Genetics [39], 207-211
Journal Article
Hanisch, Zien, Zimmer, Lengauer
[-]
2002Co-clustering of biological networks and gene expression data
In: Proceedings of the Tenth Conference on Intelligent Systems for Molecular Biology (ISMB 2002), 145-154
Proceedings Article
Hanisch, Zimmer, Lengauer
[-]
2002ProML - the Protein Markup Language for specification of protein sequences, structures and families
In: In Silico Biology [2], 313 - 324
Journal Article
Hannemann, Schön, Jansen, Putz, Lengauer
[-]
2004Modelling amorphous Si3B3N7: Structure and elastic properties
In: Physical Review [B 70], 144201-144201
Journal Article
Harrigan, McGovern, Dong, Thielen, Jensen, Mo, Chapman, Lewis, James, Valdez
[-]
2009Screening for HIV tropism using population-based V3 genotypic analysis: a retrospective outcome analysis using stored plasma screening samples from MOTIVATE-1
In: Abstracts presented at the XVIII International HIV Drug Resistance Workshop : Basic Principles & Clinical Implications, A17-A17
Poster
Harris, Wang, Coarfa, Nagarajan, Hong, Downey, Johnson, Fouse, Delaney, Zhao, Olshen, Ballinger, Zhou, Forsberg, Gu, Echipare, O'Geen, Lister, Pelizzola, Xi, Epstein, Bernstein, Hawkins, Ren, Chung, Gu, Bock, Gnirke, Zhang, Haussler, Ecker, Li, Farnham, Waterland, Meissner, Marra, Hirst, Milosavljevic, Costello
[-]
2010Comparison of sequencing-based methods to profile DNA methylation and identification of monoallelic epigenetic modifications
In: Nature Biotechnology [28], 1097-1105
Journal Article
Hartmann
[-]
2008Modeling of Flexible Side Chains for Protein-Ligand Docking
Universität des Saarlandes
Thesis - PhD thesis
Hartmann, Antes, Lengauer
[-]
2009Docking and scoring with alternative side-chain conformations
In: Proteins: Structure, Function, and Bioinformatics [74], 712-726
Journal Article
Hartmann, Antes, Lengauer
[-]
2007Attachment IconIRECS: A new algorithm for the selection of most probable ensembles of side-chain conformations in protein models.
In: Protein Science [16], 1294-1307
Journal Article
Hauschild
[-]
2011Modeling HIV Neutralization
Universität des Saarlandes
Thesis - Masters thesis
Hauschild, Baumbach, Baumbach
[-]
2013Attachment IconPaving the Way for Automated Clinical Breath Analysis and Biomarker DetectionMiscellaneous
Hauschild, Baumbach, Baumbach
[-]
2012Attachment IconIntegrated statistical learning of metabolic ion mobility spectrometry profiles for pulmonary disease identification
In: Genetics and Molecular Research [11], 2733-2744
Electronic Journal Article
Hauschild, Kopczynski, D'Addario, Baumbach, Rahmann, Baumbach
[-]
2013Peak Detection Method Evaluation for Ion Mobility Spectrometry by using Machine Learning Approaches
In: Metabolites [3], 277-293
Electronic Journal Article
Hauschild, Schneider, Pauling, Rupp, Jang, Baumbach, Baumbach
[-]
2012Attachment IconComputational Methods for Metabolomic Data Analysis of Ion Mobility Spectrometry Data - Reviewing the State of the Art
In: Metabolites [2], 733-755
Electronic Journal Article
Heckmann-Pohl, Bastian, Altmeier, Antes
[-]
2006Improvement of the fungal enzyme pyranose 2-oxidase using protein engineering
In: Journal of Biotechnology [124], 26-40
Journal Article
Heger, Thielen, Gilles, Obermeier, Lengauer, Kaiser, Trapp
[-]
2012APOBEC3G/F a one possible driving source for co-receptor switch of the human immunodeficiency virus-1
In: Medical Microbiology and Immunology [201], 7-16
Journal Article
Heger, Thielen, Gilles, Obermeier, Lengauer, Kaiser, Trapp
[-]
2011APOBEC3G/F as one possible driving force for co-receptor switch of the human immunodeficiency virus-1
In: Medical Microbiology and Immunology [201], 7-16
Journal Article
Heil, Ludwig, Lichtenberg-Fraté, Lengauer
[-]
2006Computational recognition of potassium channel sequences
In: Bioinformatics [13], 1562-1568
Journal Article
Hessler, Zimmermann, Matter, Evers, Naumann, Lengauer, Rarey
[-]
2005Multiple-Ligand-Based Virtual Screening: Methods and Applications of the MTree Approach
In: Journal of Medicinal Chemistry [48], 6575-6584
Journal Article
Hindle, Rarey, Buning, Lengauer
[-]
2002Flexible docking under pharmacophore type constraints
In: Journal of Computer-Aided Molecular Design [16], 129-149
Journal Article
Hobler
[-]
2006Docking of monosaccharids into the wild type and mutants of pyranose 2-oxidase
Universität des Saarlandes
Thesis - Bachelor thesis
Hoffmann, Schnaible, Wefing, Albrecht, Hanisch, Zimmer
(Ed: Hoffmann)
[-]
2002A new method for the fast solution of protein-3D-structures, combining experiments and bioinformatics
In: Coupling of Biological and Electronic Systems: Proceedings of the 2nd Caesarium, Bonn, 1-3 November 2000, 59-78
Proceedings Article
Hofmann, Chung, Osbahr, Susser, Karey, Mihm, Welsch, Lötsch, Sarrazin, Zeuzem, Herrmann
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2011Impact of ribavirin on HCV replicon RNA decline during treatment with interferon-α and the protease inhibitors boceprevir or telaprevir
In: Antiviral Therapy [16], 695-704
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Hofmann, Fernandez, Herrmann, Welsch, Mihm, Kronenberg, Feldmann, Spengler, Zeuzem, Sarrazin
[-]
2007Somatic hypermutation and mRNA expression levels of the BCL-6 gene in patients with hepatitis C virus-associated lymphoproliferative diseases
In: Journal of Viral Hepatitis [14], 484-491
Journal Article
Hofmann, Herrmann, Kronenberger, Merkwirth, Welsch, Lengauer, Zeuzem, Sarrazin
[^]
2004Association of HCV-related mixed cryoglobulinemia with specific mutational patterns of the HCV E2 protein and CD81 expression on peripheral B lymphocytes
In: Blood [104], 1228-1229
Journal Article
Hofmann, Welsch, Takahashi, Miyajima, Mihm, Krick, Zeuzem, Sarrazin
[-]
2007Identification and in silico characterization of a novel compound heterozygosty associated with hereditary aceruloplasminemia
In: Scandinavian Journal of Gastroenterology [42], 1088-1094
Journal Article
Hoinka
[-]
2011Finding the Hairpin in the Haystack: Towards an High Throughput in Silico Pipeline for Aptamer Motif Identification using SELEX Data
Universität des Saarlandes
Thesis - Masters thesis
Hornstein, Hoffmann, Alexa, Yamanaka, Müller, Jung, Rahnenführer, Schulz
[-]
2008Protein phosphatase and TRAIL receptor genes as new candidate tumor genes on chromosome 8p in prostate cancer
In: Cancer Genomics & Proteomics [5], 123-136
Journal Article
Huthmacher
[-]
2006Decomposing Protein Networks Into
Domain-Domain Interactions
Eberhard Karls University Tübingen
Thesis - other
Ifrim
[-]
2005A Bayesian Learning Approach to Concept-Based Document Classification
Universität des Saarlandes
Thesis - Masters thesis
Immesberger
[-]
2005Attachment IconA Prefiltering Method to Speed up Protein
Structure Prediction
Universität des Saarlandes
Thesis - Bachelor thesis
Ivanova
[-]
2011Comparison of methods for discovering genomic aberrations relevant for cancer
Universität des Saarlandes
Thesis - Masters thesis
James, Das, Rahnenführer, Ahmad
[-]
2004Cellular and Molecular Characterization of Early and Late Retinal Stem Cells/Progenitors: Differential Regulation of Proliferation and Context Dependent Role of Notch Signaling
In: Journal of Neurobiology [61], 359-376
Journal Article
James, Das, Rahnenführer, Leon, Ahmad
[-]
2003Identification of rat brahma (rBRM), a subunit of SWI/SNF chromatin remodeling complex: Involvement in the differentiation of retinal stem cells/progenitorsMiscellaneous
James, Das, Zhao, Rahnenführer, Ahmad
[-]
2004Identification of c-Kit receptor as a regulator of adult neural stem cells in the mammalian eye: interactions with Notch signaling
In: Developmental Biology [273], 87-105
Journal Article
Janssen, Rahnenführer
[Janssen]
2003A hazard based approach to dependence tests for bivariate censored models
In: Mathematical Methods in Statistics [11], 297-322
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Jenkinson, Albrecht, Birney, Blankenburg, Down, Finn, Hermjakob, Hubbard, Jimenez, Jones, Kähäri, Kulesha, Macías, Reeves, Prlić
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2008Integrating biological data - the Distributed Annotation System
In: BMC Bioinformatics [9], S3.1-7
Journal Article
Jing
[-]
2011A comprehensive analysis of the illumina Infinium assay
Universität des Saarlandes
Thesis - Masters thesis
Johannsen
[-]
2010Random Combinatorial Structures and Randomized Search Heuristics
Universität des Saarlandes
Thesis - PhD thesis
Jose, Betschieder, Ray, Lengauer, Zangen
[-]
2003New inhibitors of human cathepsin G identified by surface display library screening and peptide-protein docking
In: 7th International Symposium on Pharmaceutical Sciences (ISOPS-7), 46-49
Proceedings Article
Jung
[-]
2006Yamada Analyzer - A tool for fast calculation of genomic attributes
Universität des Saarlandes
Thesis - Bachelor thesis
Junge
[-]
2011Unsupervised dissection of cancer types based on genomic, epigenomic and transciptomic features
Universität des Saarlandes
Thesis - Bachelor thesis
Kacprowski
[-]
2011Disease gene prioritization by combining network information and functional knowledge
Universität des Saarlandes
Thesis - Masters thesis
Kacprowski
[-]
2010Analysis of protein complexes and tissue-spedific expression
Universität des Saarlandes
Thesis - Bachelor thesis
Kacprowski, Doncheva, Albrecht
[-]
2013Attachment IconNetworkPrioritizer: a versatile tool for network-based prioritization of candidate disease genes or other molecules
In: Bioinformatics [29], 1471-1473
Journal Article
Kämper, Apostolakis, Lengauer
(Ed: Borkakoti)
[-]
2002Docking of Bacterial Cell-Wall Fragments into Glycopeptide Antibiotics
In: From Genes to Drugs via Crystallography: 33rd crytallographic course at the E. Majorana Center, 49
Poster
Kämper, Apostolakis, Rarey, Marian, Lengauer
[-]
2006Fully Automated Flexible Docking of Ligands into Flexible Synthetic Receptors Using Forward and Inverse Docking Strategies
In: Journal of Chemical Information and Modeling [46], 903-911
Journal Article
Kämper, Apostolakis, Rarey, Marian, Lengauer
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2001Docking of Ligands into Artificial ReceptorsMiscellaneous
Kämper, Apostolakis, Rarey, Marian, Lengauer
[Apostolakis, Rarey, Marian]
2001Docking of Ligands into Artificial Receptors
In: Electronically Excited Molecules: Structure and Dynamics, 37th Symposium for Theoretical Chemistry, P76
Proceedings Article
Kämper, Kaspar, Lengauer
[-]
2005Efficient conformational analysis of synthetic receptors with macrocyclic and fused ring systems
In: Synthetic Receptors 2005: Second World Congress on Synthetic Receptors, O4
Proceedings Article
Kämper, Lengauer
[-]
2003ECLIPPSE: Environment for Chemical Library Inspection, Pre- and Postprocessing, and Screening Evaluation. User GuideManual
Kämper, Lengauer
[-]
2003Virtual Screening for novel Urease Inhibitors
In: Proceedings of the International Workshop on New Approaches in Drug Design & Discovery, 39
Poster
Kämper, Lengauer
[-]
2002Docking of Ligands into Molecular Tweezers and Molecular Clips
In: Workshop of the SFB 624 'Templates', ?-?
Poster
Kämper, Rognan, Lengauer
(Ed: Lengauer)
[-]
2007Lead Identification by Virtual Screening
In: Bioinformatics - From Genomes to Therapies 2. Getting at the Inner Workings: Molecular Interactions, 651-704
Part of a Book
Kaiser, Boussaad, Lehmann, Däumer, Sing, Schmeisser, Wyen, Fätkenheuer
[-]
2005Stable coreceptor usage of HIV-1 in patients with ongoing treatment failure on HAART
In: Proceedings of the 3rd European HIV Drug Resistance Workshop, -
Proceedings Article
Kalaghatgi
[-]
2012A Phylodynamic Study of HIV Transmission Networks in Europe
Universität des Saarlandes
Thesis - Masters thesis
Kalaghatgi, Lawyer
[-]
2013Inter-country mixing in HIV transmission clusters: a pan-European phylodynamics study
In: Abstract Book 11th European HIV & Hepatitis Workshop, 9
Poster
Kalinina, Oberwinkler, Glass, Kräusslich, Russell, Briggs
[-]
2012Computational Identification of Novel Amino-Acid Interactions in HIV Gag via Correlated Evolution
In: PLoS ONE [7], e42468,1-e42468,5
Electronic Journal Article
Kalinina, Pfeifer, Lengauer
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2013Modelling binding between CCR5 and CXCR4 receptors and their ligands suggests the surface electrostatic potential of the co-receptor to be a key player in the HIV-1 tropism
In: Retrovirology [10], 130
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Kamp, Wolf, Bravo, Kraus, Krause, Neumann, Winskowsky, Thielen, Werner, Schnierle
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2010Decreased HIV diversity after allogeneic stem cell transplantation of an HIV-1 infected patient: a case report.
In: Virology Journal [7], 55,1-55,9
Electronic Journal Article
Kamradt, Jung, Wahrheit, Tolosi, Rahnenführer, Schilling, Walker, Davis, Stöckle, Meltzer, Wullich
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2007Detection of Novel Amplicons in Prostate Cancer by Comprehensive Genomic Profiling of Prostate Cancer Cell Lines Using Oligonucleotide-Based ArrayCGH
In: PLoS ONE [2], e769
Electronic Journal Article
Kaspar
[-]
2006Automated conformational analysis of macrocyclic ring systems
Universität des Saarlandes
Thesis - Masters thesis
Kaspar
[-]
2005Attachment IconConformational Analysis of Macrocyclic Ring Systems
Universität des Saarlandes
Thesis - Bachelor thesis
Ketter, Kim, Storck, Rahnenführer, Romeike, Steudel, Zang, Henn
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2007Attachment IconHyperdiploidy defines a distinct cytogenetic entity of meningiomas
In: Journal of Neuro-Oncology [83], 213-221
Journal Article
Ketter, Urbschat, Henn, Feiden, Beerenwinkel, Lengauer, Steudel, Zang, Rahnenführer
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2007Application of oncogenetic trees mixtures as a biostatistical model of the clonal cytogenetic evolution of meningiomas
In: International Journal of Cancer [121], 1473-1480
Journal Article
Kircher
[-]
2007In silico analysis of microRNA genes on human chromosome 14 and mouse chromosome 12
Universität des Saarlandes
Thesis - Masters thesis
Kircher, Bock, Paulsen
[-]
2008Attachment IconStructural conservation versus functional divergence of maternally expressed microRNAs in the Dlk1/Gtl2 imprinting region
In: BMC Genomics [9], 346
Journal Article
Klingen
[-]
2012Automatic Recombination Analysis Using Recoo and Mebitoo
Universität des Saarlandes
Thesis - Bachelor thesis
Knoepfel, Di Giallonardoc, Däumer, Thielen, Metzner
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2011In-depth analysis of G-to-A hypermutation rate in HIV-1 env DNA induced by endogenous APOBEC3 proteins using massively parallel sequencing
In: Journal of Virological Methods [71], 329-338
Journal Article
König
[-]
2012Automatic detection of loss of heterozygosity in cancer
Universität des Saarlandes
Thesis - Masters thesis
König
[-]
2010Env-wide analysis of coreceptor determining sites and subtype-specific differences in HIV-1
Universität des Saarlandes
Thesis - Bachelor thesis
Kono, Bozek, Domingues, Shioda, Nakayama
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2009Impact of a single amino acid in the variable region 2 of the Old World monkey TRIM5alpha SPRY (B30.2) domain on anti-human immunodeficiency virus type 2 activity
In: Virology [388], 160-168
Journal Article
Korbel
[-]
2007Identification of Symmetries in Molecules and Complexes
Universität des Saarlandes
Thesis - Masters thesis
Koser
[-]
2012Reconstructing anecestral methylation states in phylogenetic trees
Universität des Saarlandes
Thesis - Masters thesis
Krier
[-]
2005Attachment IconMotif Search in Protein Sequences for Protein
Structure Prediction
Universität des Saarlandes
Thesis - Bachelor thesis
Krol, Blom, Winnebald, Berhörster, Barnett, Goesmann, Baumbach, Becker
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2011RhizoRegNet - A database of rhizobial transcription factors and regulatory networks.
In: Journal of Biotechnology [155], 127-134
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Kuhn Cuellar
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2010A probabilistic algorithm for matching protein structures - and its application to detecting functionally relevant patterns
Universität des Saarlandes
Thesis - Masters thesis
Kumar, Sun, Vamathevan, Li, Ingraham, Palmer, Huang, Brown
[-]
2011Comparative Genomics of Klebsiella pneumoniae Strains with Different Antibiotic Resistance Profiles
In: Antimicrobial Agents and Chemotherapy [55], 4267-4276
Journal Article
Kunert
[-]
2011Maximal Common Subgraph DAGs: Theory and Application to Virtual Screening in Drug Development
Universität des Saarlandes
Thesis - PhD thesis
Kupfer, Sing, Schüffler, Hall, Kurz, McKeown, Schneweis, Eberl, Oldenburg, Brackmann, Rockstroh, Spengler, Däumer, Kaiser, Lengauer, Matz
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2007Fifteen years of env C2V3C3 evolution in six individuals clonally infected with human immunodeficiency virus type 1
In: Journal of Medical Virology [79], 1629-1639
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Kuroishi, Bozek, Shioda, Nakayama
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2010A single amino acid substitution of the human immunodeficiency virus type 1 capsid protein affects viral sensitivity to TRIM5 alpha.
In: Retrovirology [7], 58,1-58,10
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Lange, Roomp, Dragan, Nattermann, Michalk, Spengler, Weich, Lengauer, Zeuzem, Berg, Sarrazin
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2010HLA class I allele associations with HCV genetic variants in patients with chronic HCV genotypes 1a or 1b infection
In: Journal of Hepatology [53], 1022-1028
Journal Article
Lawyer, Altmann, Thielen, Zazzi, Sönnerborg, Lengauer
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2011HIV-1 mutational pathways under multidrug therapy
In: AIDS Research and Therapy [8], 1-13
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Lawyer, Ferkingstad, Nesvåg, Varnäs, Agartz
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2009Local and covariate-modulated false discovery rates applied in neuroimaging
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Lawyer, Nesvåg, Varnäs, Okugawa, Agartz
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2009Grey and white matter proportional relationships in the cerebellar vermis altered in schizophrenia
In: Cerebellum [8], 52-60
Journal Article
Lawyer, Schülter, Kaiser, Reuter, Oette, Lengauer
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2012Attachment IconEndogenous or exogenous spreading of HIV-1 in Nordrhein-Westfalen, Germany, investigated by phylodynamic analysis of the RESINA Study cohort
In: Medical Microbiology and Immunology [201], 259-269
Journal Article
Lehmann, Däumer, Bousaad, Sing, Beerenwinkel, Lengauer, Schmeisser, Wyen, Fätkenheuer, Kaiser
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2006Stable coreceptor usage of HIV in patients with ongoing treatment failure on HAART
In: Journal of Clinical Virology [37], 300-304
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Lengauer
(Ed: Bullinger)
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2007Bioinformatik
In: Technologiefüher - Grundlagen, Anwendungen, Trends, 4
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Lengauer
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2001Bioinformatik an der Schwelle zur postgenomischen Ära
In: Was wissen wir, wenn wir das menschliche Genom kennen, 56-62
Part of a Book
Lengauer
(Ed: Lengauer)
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2007Future Trends
In: Bioinformatics - From Genomes to Therapies 3. The Holy Grail: Molecular Function, 1651-1687
Part of a Book
Lengauer
(Ed: Lengauer)
[-]
2007Introduction
In: Bioinformatics - From Genomes to Therapies 1. The Building Blocks: Molecular Sequences and Structures, 1-24
Part of a Book
Lengauer
(Ed: Meyers)
[-]
2005Attachment IconInformatics (Computational Biology)
In: Growth Factors and Oncogenes in Gastrointestinal Cancers to Informatics (Computational Biology), 567-626
Part of a Book
Lengauer
(Ed: Reuse, Vollmar)
[-]
2007Strategiekonzept "Molekulare Bioinformatik"
In: Informatikforschung in Deutschland, 9
Part of a Book
Lengauer
[-]
2012Bioinformatical Assistance of Selecting Anti-HIV Therapies: Where Do We Stand?
In: Intervirology [55], 108-112
Journal Article
Lengauer
[-]
2003Analyzing resistance phenomena in HIV with bioinformatics methods
In: Bioinformatics [19], 92i
Journal Article
Lengauer
[-]
2002Ausbildung im Bereich Bioinformatik
In: Ernst & Young Report Biotechnologie, Segmentreport Bioinformatik [1], 57-58
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Lengauer
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2002Preface: Special RECOMB 2001 Issue
In: Journal of Computational Biology [9], 147-148
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2011Computermodelle in der Wissenschaft - zwischen Analyse, Vorhersage und SuggestionBook
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2007Bioinformatics - From Genomes to Therapies 1. The Building Blocks: Molecular Sequences and StructuresBook
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2007Bioinformatics - From Genomes to Therapies 2. Getting at the Inner Workings: Molecular InteractionsBook
Lengauer (ed.)
(Ed: Lengauer)
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2007Bioinformatics - From Genomes to Therapies 3. The Holy Grail: Molecular FunctionBook
Lengauer (ed.)
(Ed: Lengauer)
[-]
2001From Genomes to DrugsBook
Lengauer, Albrecht, Domingues
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2012Computational Biology
In: Encyclopedia of Molecular Cell Biology and Molecular Medicine, 1-71
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Lengauer, Albrecht, Sarrazin, Mihm, Herrmann, Welsch, Sarrazin, Traver, Zeuzem
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2005Replication enhancing mutations of the Hepatitis C virus replicon: Prevalence and clinical significance in patients with chronic Hepatitis C
In: Journal of Infectious Diseases [192], 1710-1719
Journal Article
Lengauer, Altmann, Thielen
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2009Bioinformatische Unterstützung der Auswahl von HIV Therapien
In: Informatik Spektrum [32], 320-331
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Lengauer, Altmann, Thielen, Kaiser
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2010Chasing the AIDS Virus
In: Communications of the ACM [53], 66-74
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Lengauer, Beerenwinkel, Schmidt, Walter, Kaiser, Hoffmann, Korn, Selbig
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2001Geno2pheno: a new machine learning approach to predicting phenotypic drug resistance from genotype
In: Antiviral Therapy [6], 104
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Lengauer, Bock
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2012Managing drug resistance in cancer: lessons from HIV therapy
In: Nature Reviews Cancer [12], 494-501
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Lengauer, Domingues, Sommer, Zhu
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2006Analysis and prediction of protein-protein-interaction types
In: BMC Bioinformatics [7], -
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2009Computerjagd auf das AIDSVIRUS
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2004Novel technologies for virtual screening
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2002Proceedings of the European Conference on Computational Biology (ECCB 2002)Proceedings
Lengauer, Merkwirth
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2005Automatic Generation of complementary descriptors with molecular graph networks
In: Journal of Chemical Information and Modeling [45], 1159-1168
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Lengauer, Oette, Selbig, Hoffmann, Poggensee, Hamouda, Häussinger, Kaiser (ed.)
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2007European Journal of Medical ResearchJournal
Lengauer, Rost, Schuster (ed.)
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2007Proceedings ISMB2007Proceedings
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2007Bioinformatics prediction of HIV coreceptor usage
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2001Proceedings of the 5th Annual Conference on Research in Computational Molecular Biology (RECOMB2001)Book
Lengauer, Schäfer
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2003Combinatorial Optimization Techniques for Three-Dimensional Arrangement Problems
In: Mathematics - Key Technology for the Future, 63-73
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Lengauer, Sierra, Kaiser
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2009Resistenzbestimmung
In: MMW Fortschritte in der Medizin [151], 74-75
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Lengauer, Sing
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2006Bioinformatics-assisted anti-HIV therapy
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2002An Extended Set of Haar-like Features for Rapid Object Detection
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2008Theoretical and Experimental Evaluation of a CYP106A2 Low Homology Model and Production of Mutants with Changed Activity and Selectivity of Hydroxylation
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2013Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis
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2007Attachment IconThe human genomic melting map
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Loi
[-]
2010Identifying discriminative motifs for molecular function of proteins
Universität des Saarlandes
Thesis - Masters thesis
Low, Dong, Chan, Sing, Swanstrom, Jensen, Pillai, Good, Harrigan
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2007Current V3 genotyping algorithms are inadequate for predicting X4 co-receptor usage in clinical isolates
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2008Novel Aldosterone Synthase Inhibitors with Extended Carbocyclic Skeleton by a Combined Ligand-Based and Structure-Based Drug Design Approach
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Lutsik
[-]
2010Processing of high-throughput DNA methylation data
Universität des Saarlandes
Thesis - Masters thesis
Lutsik, Feuerbach, Arand, Lengauer, Walter, Bock
[-]
2011BiQ Analyzer HT: locus-specific analysis of DNA methylation by high-throughput bisulfite sequencing
In: Nucleic Acids Research [39], W551-W556
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Mangels
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2009In Silico Models for the Prediction of Metabolism by Cytochrome P450 Enzymes
Universität des Saarlandes
Thesis - Bachelor thesis
Marcil, Brooks-Wilson, Clee, Roomp, Zhang, Yu, Collins, van Dam, Molhuizen, Loubser, Ouelette, Sensen, Fichter, Mott, Denis, Boucher, Pimstone, Genest, Kastelein, Hayden
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Maydt
[-]
2008Analysis of recombination in Molecular Sequence Data
Universität des Saarlandes
Thesis - PhD thesis
Maydt, Lengauer
[-]
2006Recco: recombination analysis using cost optimization
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Maydt, Lienhart
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2002A Fast Method for Training Support Vector Machines With a Very Large Set of Linear Features
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Mayr, Domingues, Lackner
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2007Attachment IconComparative Analysis of Protein Structure Alignments
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2010Population-based V3 genotypic tropism assay: a retrospective analysis using screening samples from the A4001029 and MOTIVATE studies
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2009The role of genomics in tracking the evolution of influenza A virus
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Meiser
[-]
2005Identification of functionally important regions in cytochrome P450 systems and a systematic analysis of various CYP P450 homology models
Universität des Saarlandes
Thesis - Bachelor thesis
Mekhubad, Bock, de Boer, Kiskinis, Meissner, Eggan
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2012Erosion of dosage compensation impacts human iPSC disease modeling
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2004Finite iteration DT-CNN - new design and operation principles
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2004Ensemble methods for classification in cheminformatics
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2003Attachment IconStochastic Gradient Descent Training of Ensembles of DT-CNN Classifiers for Digit Recognition
In: Proceedings of the 16th European Conference on Circuit Theory and Design ECCTD'03, 337-341
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2009Clinical relevance of the 2'-5'-oligoadenylate synthetase/RNase L system for treatment response in chronic hepatitis C
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2006Amino acid variations in hepatitis C virus p7 and sensitivity to antiviral combination therapy with amantadine in chronic hepatitis C
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2010Effect of ribavirin on the frequency of RNAse L cleavage sites within the hepatitis C viral genome
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Mikeska, Bock, Do, Dobrovic
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2012DNA methylation biomarkers in cancer: Progress towards clinical implementation
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Moores, Thielen, Dong, Low, Woods, Jensen, Wynhoven, Chan, Glascock, Harrigan
[-]
2008Improved detection of X4 virus by V3 genotyping: application to plasma RNA and proviral DNA
In: Antiviral Therapy, A99
Poster
Morris, Apeltsin, Newman, Baumbach, Wittkop, Su, Bader, Ferrin
[-]
2011clusterMaker: A Multi-algorithm Clustering Plugin for Cytoscape
In: BMC Bioinformatics [12], 436,1-436,14
Journal Article
Moser, Ekawardhani, Kumsta, Palmason, Bock, Athanassiadou, Lesch, Meyer
[-]
2009Attachment IconFunctional Analysis of a Potassium-Chloride Co-Transporter 3 (SLC12A6) Promoter Polymorphism Leading to an Additional DNA Methylation Site
In: Neuropsychopharmacology [34], 458-467
Journal Article
Müller
[-]
2012Extracting pathways from biological networks incorporating omics data, introducing a webinterface for KeyPathwayMiner
Universität des Saarlandes
Thesis - Masters thesis
Müller
[-]
2009Assessing Antibody Neutralization of HIV-1 as an Initial Step in the Search for gp160-based Immunogens
Universität des Saarlandes
Thesis - Masters thesis
Müller
[-]
2008Inferring virological response to antiretroviral combination therapy based on past treatment lines
Universität des Saarlandes
Thesis - Bachelor thesis
Müller
[-]
2007Using Shape Retrieval Techniques for Identifying Similar Protein Binding Sites
Universität des Saarlandes
Thesis - Masters thesis
Nebot, Ye, Albrecht, Eom, Weikum
[-]
2011DIDO: a disease-determinants ontology from web sources
In: Proceedings of the 20th International Conference on World Wide Web (WWW 2011), 237-240
Proceedings Article
Neumann-Fraune, Beggel, Pfister, Kaiser, Verheyen
[-]
2013High frequency of complex mutational patterns in lamivudine resistant hepatitis B virus isolates
In: Journal of Medical Virology [200], 39-49
Journal Article
Neumann, Kohlbacher, Merkwirth, Lengauer
[-]
2006A Fully Computational Model for Predicting Percutaneous Drug Absorption
In: Journal of Chemical Information and Modeling [1], 424-429
Journal Article
Neumann, Kohlbacher, Merkwirth, Lengauer
[-]
2006Prediction of percutaneous drug absorption
In: Journal of Chemical Information and Modeling [1], 424-429
Journal Article
Nickels
[-]
2005Attachment IconGenerating Molecular Hashcodes for
Finding Duplicates in Virtual Screening
Libraries
Universität des Saarlandes
Thesis - Bachelor thesis
Nishida, Hirano, Tsukamoto, Nagano, Ikegami, Roomp, Ishihara, Sakane, Zhang, Tsujii, Matsuyama, Ohama, Matsuura, Ishigami, Sakai, Hiraoka, Hattori, Wellington, Yoshida, Misugi, Hayden, Egashira, Yamashita, Matsuzawa
[Nishida, Hirano, Tsukamoto, Nagano, Ikegami, Ishihara, Sakane, Zhang, Tsujii, Matsuyama, Ohama, Matsuura, Ishigami, Sakai, Hiraoka, Hattori, Wellington, Yoshida, Misugi, Hayden, Egashira, Yamashita, Matsuzawa]
2002Expression and Functional Analyses of Novel Mutations ot ATP-Binding Cassette Transporter-1 in Japanese Patients with High-Density Lipoprotein Deficiency
In: Biochemical and Biophysical Research Communications [290], 713-721
Journal Article
Obermeier, Berg, Sichtig, Braun, Däumer, Walter, Noah, Wolf, Müller, Stürmer, Thielen, Kaiser
[-]
2008Determination of HIV-1 co-receptor usage in German patients – comparison of genotypic methods with the TROFILE® phenotypic assay
In: Abstracts of the Ninth International Congress on Drug Therapy in HIV Infection, 123
Poster
Obermeier, Camacho, Charpentier, Deschamps, Eberle, Gürtler, Ruelle, Pironti, Brun-Veziet, Stürmer, Kaiser
(Ed: Kippax, Salif Sow, Wainberg, Heidari)
[-]
2012HIV2EU: supporting standardized HIV-2 drug resistance interpretation in Europe
In: Journal of the International AIDS Society, 135
Poster
Obermeier, Pironti, Berg, Braun, Däumer, Eberle, Ehret, Kaiser, Kleinkauf, Korn, Kücherer, Müller, Noah, Stürmer, Thielen, Wolf, Walter
[-]
2012HIV-GRADE: A Publicly Available, Rules-Based Drug Resistance Interpretation Algorithm Integrating Bioinformatic Knowledge
In: Intervirology [55], 102-107
Journal Article
Obermeier, Sichtig, Braun, Däumer, Walter, Noah, Wolf, Müller, Stürmer, Kaiser, Thielen
[-]
2008Determination of HIV-1 coreceptor usage in German patients - comparison of genotypic methods with the TROFILE phenotypic assay
In: Antiviral Therapy, A112
Poster
Öhsen von, Sommer, Zimmer, Lengauer
[-]
2004Arby: Automatic protein structure prediction using profile-profile alignment and confidence measures
In: Bioinformatics [20], 2228-2235
Journal Article
Oette, Schulter, Rosen-Zvi, Peres, Zazzi, Sonnerborg, Struck, Altmann, Kaiser
[-]
2012Efficacy of antiretroviral therapy switch in HIV-infected patients: A 10-year analysis of the EuResist cohort
In: Intervirology [55], 160-166
Journal Article
Olsen, Antony, Ryde, Adolph, Hemmingsen
[-]
2003Lactam hydrolysis catalyzed by mononuclear metallo-beta-lactamases: a density functional study
In: Journal of Physical Chemistry / B [107], 2366-2375
Journal Article
Patil
[-]
2013Genome Signature based Sequence Comparison for Taxonomic Assignment and tree inference
Universität des Saarlandes
Thesis - PhD thesis
Pauling, Röttger, Neuner, Salgado, Collado-Vides, Kalaghatgi, Azevedo, Tauch, Pühler, Baumbach
[-]
2012On the trail of EHEC/EAEC - unraveling the gene regulatory networks of human pathogenic Escherichia coli bacteria
In: Integrative Biology [4], 728-733
Journal Article
Pauling, Röttger, Tauch, Azevedo, Baumbach
[-]
2012CoryneRegNet 6.0 - Updated database content, new analysis methods and novel features focusing on community demands
In: Nucleic Acids Research [40], D610-D614
Journal Article
Peinado, Lengauer
[-]
2003Parallel "go with the winners algorithms" in Distributed Memory Models
In: Journal of Parallel and Distributed Processing [63], 801-814
Journal Article
Perner
[-]
2010Finding local similarities in gene expression patterns between partially reprogrammed cells and know cell types using a module network approach
Universität des Saarlandes
Thesis - Masters thesis
Perner
[-]
2008Attachment IconSemi-Supervised Learning for Predicting Anti-HIV Drug Resistance
Universität des Saarlandes
Thesis - Bachelor thesis
Pfeifer
[-]
2006Development of a fast
geometry-based screening
compound prefiltering technique
Universität des Saarlandes
Thesis - Bachelor thesis
Pfeifer, Lengauer
[-]
2013Association Between HIV-1 Coreceptor Usage and Resistance to Some Broadly Neutralizing Antibodies
In: Proceedings of the AIDS Vaccine Conference 2013, A-1-A-208
Poster
Pfeifer, Lengauer
[-]
2012Improving coreceptor usage prediction in the clinic using hints from next generation sequencing data
In: Bioinformatics [28], i589-i595
Journal Article
Pfeifer, Lengauer
[-]
2012Attachment IconImproving HIV coreceptor usage prediction in the clinic using hints from next-generation sequencing data
In: Bioinformatics [28], i589-i595
Journal Article
Pironti
[-]
2013HIV-1 fitness landscape models for indinavir treatment pressure using observed evolution in longitudinal sequence data are predictive for treatment failure
In: Infection, Genetics and Evolution [19], 349–360
Journal Article
Pironti
[-]
2009Probabilistic disease gene prioritization
Universität des Saarlandes
Thesis - Masters thesis
Pironti, Altmann, Büch, Lengauer
[-]
2011A Computational Method for Predicting First-Line Antiretroviral Therapy Success
In: Abstract Book. 9th Workshop on HIV & Hepatitis Treatment Strategies & Antiviral Drug Resistance, 94
Poster
Pironti, Lengauer, Kaiser, Schülter, Verheyen
[-]
2012Characterization of HIV-1 Gag Subtype C
In: Abstract Book. 9th Workshop on HIV \& Hepatitis Treatment Strategies \& Antiviral Drug Resistance, 40-41
Poster
Pironti, Lengauer, Pfeifer
[-]
2014Simulation of Sanger-sequencing errors in the context of genotypic tropism determination
In: Antiviral Therapy, A81
Poster
Pironti, Lengauer, Pfeifer
[-]
2013Effects of sequencing errors on geno2pheno[coreceptor] predictions
In: Abstract Book 11th European Meeting on HIV & Hepatitis, 23-24
Poster
Pironti, Lengauer, Pfeifer
[-]
2013In silico analysis of the effects of sequencing errors on geno2pheno[coreceptor]
In: Abstract Book of the International Workshop on HIV&Hepatitis Virus, A142
Poster
Pironti, Pfeifer, Kaiser, Walter, Lengauer
(Ed: Kippax, Sow, Wainberg)
[-]
2014Improved therapy-success prediction with GSS estimated from clinical HIV-1 sequences
In: Abstract Supplement of the HIV Drug Therapy Glasgow Congress 2014, 155
Poster
Pironti, Pfeifer, Kaiser, Walter, Lengauer
[-]
2014Accurate prediction of drug-exposure without using established drug-resistance mutations
In: Antiviral Therapy, A75
Poster
Pironti, Pfeifer, Kaiser, Walter, Lengauer
[-]
2014Improved HIV-1 drug-exposure reconstruction with linear support vector machines
In: Reviews in Antiviral Therapy & Infectious Diseases, 67
Poster
Pironti, Pfeifer, Lengauer
[-]
2014Accurate prediction of drug-exposure without using established drug-resistance mutations
In: Antiviral Therapy, A75
Poster
Pironti, Pfeifer, Lengauer
[-]
2014Improved HIV-1 drug-exposure reconstruction with linear support vector machines
In: Reviews in Antiviral Therapy & Infectious Diseases, 67
Poster
Pironti, Sierra, Kaiser, Lengauer, Pfeifer
[-]
2014Simulation of Sanger-sequencing errors in the context of genotypic tropism determination
In: Antiviral Therapy, A81
Poster
Plotz, Welsch, Giron-Monzon, Friedhoff, Albrecht, Piiper, Biondi, Lengauer, Zeuzem, Raedle
[-]
2006Attachment IconMutations in the MutSalpha interaction interface of MLH1 can abolish DNA mismatch repair
In: Nucleic Acids Research [34], 6574-6586
Journal Article
Prlic, Domingues, Lackner, Sippl
[-]
2004WILMA-automated annotation of protein sequences
In: Bioinformatics [20], 127-128
Journal Article
Prosperi, Altmann, Rosen-Zvi, Aharoni, Gabor, Fulop, Sonnerborg, Schulter, Struck, Ulivi, Vandamme, Vercauteren, Zazzi
[-]
2009Investigation of expert rule bases, logistic regression, and non-linear machine learning techniques for predicting response to antiretroviral treatment
In: Antiviral Therapy [14], 433-442
Journal Article
Prosperi, Rosen-Zvi, Altmann, Zazzi, Di Giambenedetto, Kaiser, Schülter, Struck, Sloot, van de Vijver, Vandamme, Sönnerborg
[-]
2010Antiretroviral Therapy Optimisation without Genotype Resistance Testing: A Perspective on Treatment History Based Models
In: PLoS ONE [5], e13753,1-e13753,8
Electronic Journal Article
Radivojac, Clark, Oron, Schnoes, Wittkop, Sokolov, Graim, Funk, Verspoor, Ben-Hur, Pandey, Yunes, Talwalkar, Repo, Souza, Piovesan, Casadio, Wang, Cheng, Fang, Gough, Koskinen, T\"{o}r\"{o}nen, Nokso-Koivisto, Holm, Cozzetto, Buchan, Bryson, Jones, Limaye, Inamdar, Datta, Manjari, Joshi, Chitale, Kihara, Lisewski, Erdin, Venner, Lichtarge, Rentzsch, Yang, Romero, Bhat, Paccanaro, Hamp, Ka\ss ner, Seemayer, Vicedo, Schaefer, Achten, Auer, Boehm, Braun, Hecht, Heron, H\"{o}nigschmid, Hopf, Kaufmann, Kiening, Krompass, Landerer, Mahlich, Roos, Bj\"{o}rne, Salakoski, Wong, Shatkay, Gatzmann, Sommer, Wass, Sternberg, Skunca, Supek, Bo\v{s}njak, Panov, D\v{z}eroski, Smuc, Kourmpetis, van Dijk, Braak, Zhou, Gong, Dong, Tian, Falda, Fontana, Lavezzo, {Di Camillo}, Toppo, Lan, Djuric, Guo, Vucetic, Bairoch, Linial, Babbitt, Brenner, Orengo, Rost, Mooney, Friedberg
[-]
2013A large-scale evaluation of computational protein function prediction
In: Nature Methods [10], 221-227
Journal Article
Rahnenführer
(Ed: Denison, Hansen, Holmes, Mallick, Yu)
[-]
2003Statistical Inference for Clustering Microarrays
In: Proceedings of the MSRI Workshop: Nonlinear Estimation and Classification, 323-332
Proceedings Article
Rahnenführer
(Ed: Schader, Gaul, Vichi)
[-]
2003Efficient Clustering Methods for Tumor Classification with Microarrays
In: Proceedings of the 26th Annual Conference of the Gesellschaft für Klassifikation, 670-679
Proceedings Article
Rahnenführer
[-]
2006Statistical methods for the biological interpretation of genome-wide measurements
Universität des Saarlandes
Thesis - Habilitation thesis
Rahnenführer
[-]
2005Clustering algorithms and other exploratory methods for microarray data analysis
In: Methods of Information in Medicine [44], 444-448
Journal Article
Rahnenführer
[-]
2005Image analysis for cDNA microarrays
In: Methods of Information in Medicine [44], 405-407
Journal Article
Rahnenführer
[-]
2003On preferences of general two-sided tests with applications to Kolmogorov-Smirnov-type tests
In: Statistics & Decisions [21], 115-136
Journal Article
Rahnenführer
[-]
2002Hybrid clustering for microarray analysis combining intensity and shape features
In: Poster book of the European Conference on Computational Biology, Saarbrücken, Germany 2002, -
Poster
Rahnenführer
[-]
2002Multivariate permutation tests for the k-sample problem with clustered data
In: Computational Statistics [17], 165-184
Journal Article
Rahnenführer, Beerenwinkel, Schulz, Hartmann, von Deimling, Wullich, Lengauer
[-]
2005Estimating cancer survival and clinical outcome based on genetic tumor progression scores
In: Bioinformatics [21], 2438-2446
Journal Article
Rahnenführer, Bozinov
[-]
2004Hybrid clustering for microarray image analysis combining intensity and shape features
In: BMC Bioinformatics [5], 1-11
Journal Article
Rahnenführer, Bozinov
[-]
2003Comparative quality analyses for hybrid clustering of microarray images
In: Proceedings of the Sventh Annual International Conference on Computational Biology, -
Poster
Rahnenführer, Bozinov
[Bozinov]
2002Unsupervised technique for robust target separation and analysis of DNA microarray spots through adaptive pixel clustering
In: Bioinformatics [18], 747-756
Journal Article
Rahnenführer, Domingues, Maydt, Lengauer
[-]
2004Calculating the statistical significance of changes in pathway activity from gene expression data
In: Statistical Applications in Genetics and Molecular Biology [3], Article 16
Electronic Journal Article
Rahnenführer, Futschik
[-]
2003Cost-effective screening for differentially expressed genes in microarray experiments based on normal mixtures
In: Austrian Journal of Statistics [32], 225-238
Journal Article
Rahnenführer, Lengauer
(Ed: Lengauer)
[-]
2007Analysis of Expression Data: Classification of genes
In: Bioinformatics - From Genomes to Therapies 2. Getting at the Inner Workings: Molecular Interactions, 993-1021
Part of a Book
Ralser, Albrecht, Nonhoff, Lengauer, Lehrach, Krobitsch
[-]
2005An integrative approach to gain insights into the cellular function of human ataxin-2
In: Journal of Molecular Biology [346], 203-214
Journal Article
Ralser, Nonhoff, Albrecht, Lengauer, Wanker, Lehrach, Krobitsch
[-]
2005Ataxin-2 and huntingtin interact with endophilin-A complexes to function in plastin-associated pathways
In: Human Molecular Genetics [14], 2893-2909
Journal Article
Ramirez
(Ed: Gomez Merino, Silva Rojas, Pérez Rodríguez)
[-]
2010Tutorial Cytoscape
In: Bioinformática: Aplicaciones a la genómica y proteómica, 73-98
Part of a Book
Ramírez
(Ed: Ramírez, Balbin, Betancourt-Morales, Mora-Oberlaender, Angel-Rodriguez)
[-]
2004Evolucion de la Evolucionalidad
In: Biologos lejos del equilibrio: Nuevas metaforas evolutivas, 59-87
Part of a Book
Ramirez
[-]
2012Novel Approaches to the Integration and Analysis of Systems Biology
Universität des Saarlandes
Thesis - PhD thesis
Ramírez
[-]
2004Hacia una comprension de la accion de la recombinacion genetica y la mutacion en el origen de la variacion fenotipica, mediante el analisis de la computacion evolutiva
Universidad Nacional de Colombia
Thesis - Masters thesis
Ramírez, Albrecht
[-]
2010Finding scaffold proteins in interactomes
In: Trends in Cell Biology [20], 2-4
Journal Article
Ramírez, Garcia
[-]
2000GenLab: Laboratorio virtual de genetica
In: Acta Biologica Colombiana [5], 45-48
Journal Article
Ramírez, Lawyer, Albrecht
[-]
2012Novel search method for the discovery of functional relationships
In: Bioinformatics [28], 269-276
Journal Article
Ramírez, Schlicker, Assenov, Lengauer, Albrecht
[-]
2007Computational analysis of human protein interaction networks
In: Proteomics [7], 2541-2552
Journal Article
Ramos, Carneiro, Baumbach, Azevedo, Schneider, Silva
[-]
2011Analysis of quality raw data of second generation sequencers with Quality Assessment Software
In: BMC Research Notes [4], 130,1-130,6
Journal Article
Reimer
[-]
2006Docking studies to investigate the effect of correlated mutations in the HIV-Protease on the drug resistance of HIV
Universität des Saarlandes
Thesis - Bachelor thesis
Reiss, Rebhan, Backes, Romero-Brey, Erfle, Matula, Kaderali, Poenisch, Blankenburg, Hiet, Longerich, Diehl, Ramírez, Balla, Rohr, Kaul, Bühler, Pepperkok, Lengauer, Albrecht, Eils, Schirmacher, Lohmann, Bartenschlager
[-]
2011Recruitment and activation of a lipid kinase by hepatitis C virus NS5A is essential for integrity of the membranous replication compartment
In: Cell Host & Microbe [9], 32-45
Journal Article
Reppas, Lawyer
(Ed: Simos, Psihoyios, Tsitouras, Anastassi)
[-]
2012Attachment IconLow k-shells identify bridge elements critical to disease flow in small-world networks
In: Numerical Analysis and Applied Mathematics (ICNAAM 2012), 1426-1429
Proceedings Article
Reuter
[-]
2011Estimating and Using the Uncertainty in the Phenotypic Resistance Assay of the Hepatitis B Virus to Improve IC-50 Prediction from Genotype
Universität des Saarlandes
Thesis - Bachelor thesis
Reuter, Oette, Kaiser, Lengauer, Fätkenheuer, Rockstroh, Knechten, Häussinger
[-]
2012Risk factors associated with older age in treatment-naive HIV-positive patients
In: Intervirology [55], 147-153
Journal Article
Reuter, Oette, Wilhelm, Beggel, Kaiser, Balduin, Schweitzer, Verheyen, Adams, Lengauer, Faetkenheuer, Pfister, Haeussinger
[-]
2011Attachment IconErratum to: Prevalence and characteristics of hepatitis B and C virus infections in treatment-naïve HIV-infected patients.
In: Medical Microbiology and Immunology [200], 51-51
Journal Article
Reuter, Oette, Wilhelm, Beggel, Kaiser, Balduin, Schweitzer, Verheyen, Adams, Lengauer, Faetkenheuer, Pfister, Haeussinger
[-]
2011Prevalence and characteristics of hepatitis B and C virus infections in treatment-naïve HIV-infected patients
In: Medical Microbiology and Immunology [200], 39-49
Journal Article
Rhee, Margeridon-Thermet, Nguyen, Liu, Kagan, Beggel, Verheyen, Kaiser, Shafer
[-]
2010Attachment IconHepatitis B virus reverse transcriptase sequence variant database for sequence analysis and mutation discovery
In: Antiviral Research [88], 269-275
Journal Article
Röttger, Kalaghatgi, Sun, de Castro Soares, Azevedo, Wittkop, Baumbach
[-]
2013Density Parameter Estimation for Finding Clusters of Homologous Proteins - Tracing Actinobacterial Pathogenicity Life Styles
In: Bioinformatics [29], 215-222
Journal Article
Röttger, Kreutzer, Duong Vu, Wittkop, Baumbach
(Ed: Böcker, Hufsky, Scheubert, Schleicher, Schuster)
[-]
2012Online Transitivity Clustering of Biological Data with Missing Values
In: German Conference on Bioinformatics 2012 (GCB 2012), 57-68
Electronic Proceedings Article
Röttger, Rueckert, Taubert, Baumbach
[-]
2012How Little Do We Actually Know? - On the Size of Gene Regulatory Networks.
In: IEEE/ACM transactions on computational biology and bioinformatics [9], 1293-1300
Journal Article
Roomp
(Ed: Lengauer)
[-]
2007Evolution of Drug Resistance in HIV
In: Bioinformatics - From Genomes to Therapies 3. The Holy Grail: Molecular Function, 1457-1496
Part of a Book
Roomp, Antes, Lengauer
[-]
2010Predicting MHC class I epitopes in large datasets
In: BMC Bioinformatics [11], 90,1-90,11
Electronic Journal Article
Roomp, Beerenwinkel, Sing, Schülter, Büch, Sierra-Aragon, Däumer, Hoffmann, Kaiser, Lengauer, Selbig
[-]
2006Arevir: A Secure Platform for Designing Personalized Antiretroviral Therapies Against HIV
In: Lecture Notes in Computer Science [4075], 185-194
Journal Article
Roomp, Domingues
[-]
2011Predicting interactions between T cell receptors and MHC-peptide complexes
In: Molecular Immunology [48], 553-562
Journal Article
Roomp, Rand
[-]
2009Intensive blood glucose control is safe and effective in diabetic cats using home monitoring and treatment with glargine
In: Journal of feline medicine and surgery [11], 668-682
Journal Article
Rosen-Zvi, Altmann, Prosperi, Aharoni, Neuvirth, Sönnerborg, Schülter, Struck, Peres, Incardona, Kaiser, Zazzi, Lengauer
[-]
2008Selecting anti-HIV therapies based on a variety of genomic and clinical factors
In: Proceedings of the 16th Annual International Conference on Intelligent Systems for Molecular Biology (ISMB 2008), i399-406
Proceedings Article
Rosen-Zvi, Schülter, Altmann, Sierra-Aragon, Zazzi, Sönnerborg, Oette, Lengauer, Kaiser
[-]
2008Sustaining lamivudine/emtricitabine, abacavir, zidovudine or atazanavir from a previous treatment shows a clinical benefit
In: Antiviral Therapy, A86
Poster
Rost, Gaasterland, Lengauer, Linial, Markel, McKay, Schneider, Horton, Kelso
[-]
2012Paving the future: finding suitable ISMB venues
In: Bioinformatics [28], 2556-2559
Journal Article
Ruiz, D'Afonseca, Silva, Ali, Pinto, Santos, Rocha, Lopes, Dorella, Pacheco, Costa, Turk, Seyffert, Moraes, Soares, Almeida, Castro, Abreu, Trost, Baumbach, Tauch, Schneider, McCulloch, Cerdeira, Ramos, Zerlotini, Dominitini, Resende, Coser, Oliveira, Pedrosa, Vieira, Guimaraes, Bartholomeu, Oliveira, Santos, Rabelo, Lobo, Franco, Costa, Castro, Dias, Ferro, Ortega, Paiva, Goulart, Almeida, Ferro, Carneiro, Falcao, Grynberg, Teixeira, Brommonschenkel, Oliveira, Meyer, Moore, Miyoshi, Oliveira, Azevedo
[-]
2011Evidence for Reductive Genome Evolution and Lateral Acquisition of Virulence Functions in two Corynebacterium pseudotuberculosis strains
In: PLoS One [6], e18551
Electronic Journal Article
Saigo, Altmann, Bogojeska, Müller, Nowozin, Lengauer
[-]
2011Attachment IconLearning from past treatments and their outcome improves prediction of In Vivo response to anti-HIV therapy
In: Statistical Applications in Genetics and Molecular Biology [10], 1-32
Electronic Journal Article
Saigo, Hattori, Kashima, Tsuda
[-]
2010Reaction graph kernels predict EC numbers of unknown enzymatic reactions in plant secondary metabolism
In: BMC Bioinformatics [11], S31,1-S31,7
Electronic Journal Article
Saigo, Tsuda
(Ed: Giannotti, Gunopulos)
[-]
2008Iterative Subgraph Mining for Principal Component Analysis.
In: Proceedings of the IEEE International Conference on Data Mining (ICDM2008), DM934
Proceedings Article
Salamat-Miller, Fang, Seidel, Assenov, Albrecht, Middaugh
[-]
2007Attachment IconA network-based analysis of polyanion-binding proteins utilizing human protein arrays
In: Journal of Biological Chemistry [282], 10153-10163
Journal Article
Salamat-Miller, Fang, Seidel, Smalter, Assenov, Albrecht, Middaugh
[-]
2006A network-based analysis of polyanion-binding proteins utilizing yeast protein arrays
In: Molecular and Cellular Proteomics [5], 2263-2278
Journal Article
Sander
[-]
2008Structural Descriptors for the Analysis of Protein Structure, Function, and Evolution
Universität des Saarlandes
Thesis - PhD thesis
Sander
[-]
2004Local sequence-structure relationships in proteins
Friedrich-Alexander-Universität Erlangen-Nürnberg
Thesis - other
Sander, Altmann, Lengauer
[-]
2008Computational analysis of covariation and interactions between HIV-1 reverse transcriptase and Integrase
In: Reviews in Antiviral Therapy, 113-114
Poster
Sander, Domingues, Zhu, Lengauer, Sommer
(Ed: Brazma, Miyano, Akutsu)
[-]
2008Structural descriptors of protein-protein binding sites
In: Proceedings of 6th Asia-Pacific Bioinformatics Conference, 79-88
Proceedings Article
Sander, Sing, Sommer, Low, Cheung, Harrigan, Lengauer, Domingues
[-]
2007Attachment IconStructural Descriptors of gp120 V3 Loop for the Prediction of HIV-1 Coreceptor Usage
In: PLoS Computational Biology [3], 555-564
Journal Article
Sander, Sommer, Lengauer
[-]
2006Local protein structure prediction using discriminative models
In: BMC Bioinformatics [7], 1-13
Electronic Journal Article
Sandoval, Mendez-Gonzales, Nadal, Chen, Carmona, Sayols, Moran, Heyn, Vizoso, Gomez, Sanchez-Cespedes, Assenov, Müller, Bock, Taron, Mora, Muscarella, Liloglou, Davies, Pollan, Pajares, Torre, Montuenga, Brambilla, Field, Roz, Lo Iacono, Scagliotti, Rosell, Beer, Esteller
[-]
2013A Prognostic DNA Methylation Signature for Stage I Non-Small-Cell Lung Cancer
In: Journal of Clinical Oncology [31], 4140-4147
Journal Article
Santos, Santos, Baumbach, McCulloch, Oliveira, Silva, Miyoshi, Azevedo
[-]
2011A singular value decomposition approach for improved taxonomy classification of biological sequences
In: BMC Genomics [12], S11,1-S11,15
Journal Article
Sarrazin, Mihm, Herrmann, Welsch, Albrecht, Sarrazin, Traver, Lengauer, Zeuzem
[-]
2005Clinical significance of in vitro replication-enhancing mutations of the hepatitis C virus (HCV) replicon in patients with chronic HCV infection
In: The Journal of Infectious Diseases [192], 1710-1719
Journal Article
Schäfer, Lengauer
[Schäfer]
2001Automated Layout Generation and Wiring Area Estimation for 3D Electronic Modules
In: ASME Journal of Machanical Design [123], 330-336
Journal Article
Schelhorn
[-]
2007Prediction of Domain and Motif Interactions from Protein Networks
Universität des Saarlandes
Thesis - Masters thesis
Schelhorn, Fischer, Tolosi, Altmüller, Nürnberg, Pfister, Lengauer, Berthold
[-]
2013Sensitive detection of viral transcripts in human tumor transcriptomes
In: PLOS Computational Biology [9], xx
Journal Article
Schelhorn, Lengauer, Albrecht
[-]
2008An integrative approach for predicting interactions of protein regions
In: Bioinformatics [24], i35-i41
Journal Article
Schelhorn, Mestre, Zotenko, Albrecht
[-]
2011Inferring physical protein contacts from large-scale purification data of protein complexes
In: Molecular & Cellular Proteomics [10], M110.004929,1-M110.004929,15
Electronic Journal Article
Scheller, Resa-Infante, de la Luna, Galao, Albrecht, Kaestner, Lipp, Lengauer, Meyerhans, Díez
[-]
2007Identification of PatL1, a human homolog to yeast P body component Pat1
In: Biochimica et Biophysica Acta - Molecular Cell Research [1773], 1786-1792
Journal Article
Schlicker
[-]
2010Attachment IconOntology-based Similarity Measures and their Application in Bioinformatics
Universität des Saarlandes
Thesis - PhD thesis
Schlicker
[-]
2005A Global Approach to Comparative Genomics: Comparison of Functional Annotation over the Taxonomic Tree
Universität des Saarlandes
Thesis - Masters thesis
Schlicker
[-]
2004Attachment IconAutomated Differential Analysis of Proteomes
Universität des Saarlandes
Thesis - Bachelor thesis
Schlicker, Albrecht
[-]
2010FunSimMat update: new features for exploring functional similarity
In: Nucleic Acids Research [38], D244-D248
Journal Article
Schlicker, Albrecht
[-]
2008Attachment IconFunSimMat: a comprehensive functional similarity database
In: Nucleic Acids Research [36], D434-D439
Journal Article
Schlicker, Domingues, Rahnenführer, Lengauer
[-]
2006Attachment IconA new measure for functional similarity of gene products based on Gene Ontology
In: BMC Bioinformatics [7], 1-16
Electronic Journal Article
Schlicker, Huthmacher, Ramírez, Lengauer, Albrecht
(Ed: Huson, Kohlbacher, Lupas, Nieselt, Zell)
[-]
2006Functional evaluation of domain-domain interactions and human protein interaction networks
In: German Conference on Bioinformatics (GCB 2006), 115-126
Proceedings Article
Schlicker, Huthmacher, Ramírez, Lengauer, Albrecht
[-]
2007Attachment IconFunctional evaluation of domain-domain interactions and human protein interaction networks
In: Bioinformatics [23], 859-865
Journal Article
Schlicker, Lengauer, Albrecht
[-]
2010Improving disease gene prioritization using the semantic similarity of Gene Ontology terms
In: Bioinformatics [26], i561-i567
Journal Article
Schlicker, Rahnenführer, Albrecht, Lengauer, Domingues
[-]
2007Attachment IconGOTax: investigating biological processes and biochemical activities along the taxonomic tree
In: Genome Biology [8], R33.1-10
Electronic Journal Article
Schneider, Hauschild, Baumbach, Baumbach
[-]
2013An Integrative Clinical Database and Diagnostics Platform for Biomarker Identification and Analysis in Ion Mobility Spectra of Human Exhaled Air
In: Journal of Integrative Bioinformatics [10],
Electronic Journal Article
Schreiber, Rosenstiel, Albrecht, Hampe, Krawczak
[-]
2005Genetics of Crohn disease, an archetypal inflammatory barrier disease
In: Nature Reviews Genetics [6], 376-388
Journal Article
Schüffler
[-]
2008MethMarker – A toolkit for design, optimization and validation of DNA methylation biomarkers for cancer diagnosis and therapy optimization
Universität des Saarlandes
Thesis - Masters thesis
Schüffler, Mikeska, Waha, Lengauer, Bock
[-]
2009Attachment IconMethMarker: User-friendly design and optimization of gene-specific DNA methylation assays
In: Genome Biology [10], R105:1-R105:10
Journal Article
Schuelter, Lübcke, Jensen, Zazzi, Sönnerborg, Lengauer, Incardona, Camacho, Schmit, Clotet, Kaiser, Pironti
(Ed: Kippax, Salif Sow, Wainberg, Heidari)
[-]
2012Etravirine in protease inhibitor-free antiretroviral combination therapies
In: Journal of the International AIDS Society, 155-156
Poster
Schülter, Oette, Balduin, Reuter, Rockstroh, Fätkenheuer, Esser, Lengauer, Agacfidan, Pfister, Kaiser, Akgul
[-]
2011HIV prevalence and route of transmission in Turkish immigrants
living in North-Rhine Westphalia, Germany
In: Medical Microbiology and Immunology [200], 219-223
Journal Article
Schulz, Alexa, Jung, Hader, Hoffmann, Yamanaka, Fritzsche, Wlazlinski, Müller, Lengauer, Engers, Florl, Wullich, Rahnenführer
[-]
2007Attachment IconFactor interaction analysis for chromosome 8 and DNA methylation alterations highlights innate immune response suppression and cytoskeletal changes in prostate cancer
In: Molecular Cancer [6], 1-16
Journal Article
Schulz, Pandit, Lino Cardenas, Ambalavanan, Kaminski, Bar-Joseph
[-]
2013Reconstructing dynamic microRNA-regulated interaction networks
In: Proceedings of the National Academy of Sciences of the United States [110], 15686–15691
Journal Article
Seclen, Soriano, González, Gómez, Thielen, Poveda
[-]
2011High Concordance between the Position-Specific Scoring Matrix and Geno2pheno Algorithms for Genotypic Interpretation of HIV-1 Tropism: V3 Length as the Major Cause of Disagreement
In: Journal of Clinical Microbiology [49], 3380-3382
Journal Article
Setty
[-]
2012Multi-scale computational modeling of developmental biology
In: Bioinformatics [28], 2022-2028
Journal Article
Shimakami, Welsch, Yamane, McGivern, Yi, Zeuzem, Lemon
[-]
2011Protease Inhibitor-Resistant Hepatitis C Virus Mutants With Reduced Fitness From Impaired Production of Infectious Virus
In: Gastroenterology [140], 667-675
Journal Article
Sichtig, Sierra, Kaiser, Däumer, Reuter, Schülter, Altmann, Fätkenheuer, Dittmer, Pfister, Esser
[-]
2009Evolution of raltegravir resistance during therapy
In: Journal of antimicrobial chemotherapy [64], 25-32
Journal Article
Sierra, Dzbowski, Pironti, Gueney, Thielen, Reuter, Esser, Fätkenheuer, Lengauer, Hider, Hoffmann, Pfister, Jensen, Kaiser
(Ed: Kippax, Salif Sow, Wainberg, Heidari)
[-]
2012Optimisation of baseline genotypic testing for safe and efficient maraviroc administration
In: Journal of the International AIDS Society, 101-102
Poster
Sierra, Kaiser, Lübke, Thielen, Schuelter, Heger, Däumer, Reuter, Esser, Fätkenheuer, Pfister, Oette, Lengauer
[-]
2011Prediction of HIV-1 coreceptor usage (tropism) by sequence analysis using a genotypic approach
In: Journal of Visualized Experiments [58], e3264,1-e3264,9
Electronic Journal Article
Sierra, Kaiser, Thielen, Lengauer
[-]
2007Attachment IconGenotypic coreceptor analysis.
In: European Journal of Medical Research [12], 453-462
Journal Article
Sierra, Kaiser, Thielen, Sander, Lengauer
(Ed: Jäger)
[-]
2008Genotypic Analysis of HIV Co-Receptor Usage
In: Entry Inhibitoren - Neue Formen der HIV-Therapie, 31-39
Part of a Book
Simmer, Brinkmann, Assenov, Matarese, Kaan, Lengauer, Bock, Colantuoni, Altucci, Stunnenberg
[-]
2013Comparative genome-wide DNA methylation analysis of colorectal tumor and matched human tissue
In: Epigenetics [7], 1355-1367
Journal Article
Simmer, Brinkman, Assenov, Matarese, Kaan, Sabatino, Villanueva, Huertas, Esteller, Lengauer, Bock, Colantuoni, Altucci, Stunnenberg
[-]
2012Comparative genome-wide DNA methylation analysis of colorectal tumor and matched normal tissues
In: Epigenetics [7], 1355-1367
Journal Article
Sing
[-]
2008Model-Based Anti HIV Therapy
Universität des Saarlandes
Thesis - PhD thesis
Sing
[-]
2004Learning localized rule mixtures by maximizing the area under the ROC curve, with an application to the prediction of HIV-1 coreceptor usage
Universität Freiburg
Thesis - Masters thesis
Sing, Beerenwinkel
(Ed: Schölkopf, Platt, Hoffman)
[-]
2007Attachment IconMutagenetic tree Fisher kernel improves prediction of HIV drug resistance from viral genotype
In: Advances in Neural Information Processing Systems 19, 1-9
Proceedings Article
Sing, Beerenwinkel, Kaiser, Hoffmann, Däumer, Lengauer
[-]
2005Geno2pheno[coreceptor]: a tool for predicting coreceptor usage from genotype and for monitoring coreceptor-associated sequence alterations
In: Proceedings of the 3rd European HIV Drug Resistance Workshop, -
Poster
Sing, Beerenwinkel, Lengauer
(Ed: Hernández-Orallo, Ferri, Lachiche, Falch)
[-]
2004Learning mixtures of localized rules by maximizing the area under the ROC curve
In: ROCAI-2004: 1st International Workshop on ROC Analysis in Artificial Intelligence, 89-96
Proceedings Article
Sing, Low, Beerenwinkel, Sander, Cheung, Domingues, Büch, Däumer, Kaiser, Lengauer, Harrigan
[-]
2007Predicting HIV coreceptor usage on the basis of genetic and clinical covariates
In: Antiviral Therapy [12], 1097-1106
Journal Article
Sing, Sander, Beerenwinkel, Lengauer
[-]
2006ROCR: Visualizing classifier performance in R
In: Bioinformatics [21], 3940-3941
Journal Article
Sing, Svicher, Beerenwinkel, Ceccherini-Silberstein, Däumer, Kaiser, Walter, Korn, Hoffmann, Oette, Rockstroh, Fätkenheuer, Perno, Lengauer
(Ed: Jorge, Torgo, Brazdil, Camacho, Gama)
[-]
2005Characterization of novel HIV Drug Resistance Mutations using clustering, multidimensional scaling and SVM-based feature ranking
In: Knowledge Discovery in Databases: PKDD 2005., 285-296
Proceedings Article
Siu
[-]
2005Computational prediction of MHC-peptide interactions
Universität des Saarlandes
Thesis - Masters thesis
Skrabal, Low, Dong, Sing, Cheung, Mammano, Harrigan
[-]
2007Attachment IconDetermining human immunodeficiency virus coreceptor use in a clinical setting: Degree of correlation between two phenotypic assays and a bioinformatic model
In: Journal of Clinical Microbiology [45], 279-284
Journal Article
Smolinska, Hauschild, Fijten, Dallinga, Baumbach, van Schooten
[-]
2014Current breathomics – A review on data pre-processing techniques and machine learning in metabolomics breath analysisUnpublished/Draft
Soares, Abreu, Ramos, Cerdeira, Silva, Baumbach, Trost, Tauch, Hirata, Mattos-Guaraldi, Miyoshi, Azevedo
[-]
2012PIPS: Pathogenicity Island Prediction Software
In: PLoS One [7], e30848,1-e30848,10
Electronic Journal Article
Söderhäll, Marenholz, Kerscher, Rüschendorf, Esparza-Gordillo, Worm, Gruber, Mayr, Albrecht, Rohde, Schulz, Wahn, Hubner, Lee
[-]
2007Attachment IconVariants in a novel epidermal collagen gene (COL29A1) are associated with atopic dermatitis
In: PLoS Biology [5], e242.1952-1961
Journal Article
Sommer
(Ed: Lengauer)
[-]
2007Protein Fold Recognition Based on Distant Homologs
In: Bioinformatics - From Genomes to Therapies 1. The Building Blocks: Molecular Sequences and Structures, 351-388
Part of a Book
Sommer
[-]
2009Attachment IconFrom Protein Structure to Function
Universität des Saarlandes
Thesis - Habilitation thesis
Sommer, Müller, Domingues, Sander, Weickert, Lengauer
[-]
2007Moment invariants as shape recognition technique for comparing protein binding sites
In: Bioinformatics [23], 3139-3146
Journal Article
Sommer, Rahnenführer, Domingues, de Lichtenberg, Lengauer
[-]
2004Predicting Protein Structure Classes from Function Predictions
In: Bioinformatics [20], 770-776
Journal Article
Sommer, Toppo, Sander, Lengauer, Tosatto
[-]
2006Improving the quality of protein structure models by selecting from alignment alternatives
In: BMC Bioinformatics [7], 1-11
Electronic Journal Article
Sommer, Zien, Öhsen von, Zimmer, Lengauer
[Zien, Öhsen von, Zimmer]
2002Confidence measures for protein fold recognition
In: Bioinformatics [18], 802-812
Journal Article
Sos, Michel, Zander, Weiss, Frommolt, Pfeifer, Li, Ullrich, Koker, Fischer, Shimamura, Rauh, Mermel, Fischer, Stückrath, Heynck, Beroukhim, Lin, Winckler, Shah, LaFramboise, Moriarty, Hanna, Tolosi, Rahnenführer, Verhaak, Chiang, Getz, Hellmich, Wolf, Girard, Peyton, Weir, Chen, Greulich, Barretina, Shapiro, Garraway, Gazdar, Minna, Meyerson, Wong, Thomas
[-]
2009Predicting drug susceptibility of non-small cell lung cancers based on genetic lesions
In: Journal of Clinical Investigation [119], 1727-1740
Journal Article
Speicher
[-]
2012Towards the identification of cancer subtypes by integrative clustering of molecular data
Universität des Saarlandes
Thesis - Masters thesis
Speicher
[-]
2010Network analysis of viral host factors
Universität des Saarlandes
Thesis - Bachelor thesis
Steffen
[-]
2008Computational Approaches in Supramolecular Chemistry with a special Focus on Virtual Screening
Universität des Saarlandes
Thesis - PhD thesis
Steffen, Kämper, Lengauer
(Ed: Turner)
[-]
2006Virtual screening for guest molecules of a biosensor
In: Biosensors 2006: The ninth world congress on biosensors, O66
Proceedings Article
Steffen, Kämper, Lengauer
(Ed: Turner)
[-]
2005FlexR - A new tool for predicting the structure of synthetic host-guest complexes
In: Synthetic Receptors 2005: Second World Congress on Synthetic Receptors, O7
Proceedings Article
Steffen, Kämper, Lengauer
[-]
2006Flexible Docking of Ligands into Synthetic Receptors Using a Two-Sided Incremental Construction Algorithm
In: Journal of Chemical Information and Modeling [46], 1695-1703
Journal Article
Steffen, Kämper, Lengauer
[-]
2004Development of a new tool for predicting the structure of host-guest complexes
In: Proceedings of the 2nd Summer School Medicinal Chemistry Regensburg 2004, 83
Poster
Steffen, Kämper, Lengauer
[-]
2004FlexR - Predicting the structure of host-guest complexes
In: Proceedings of the Annual Meeting of the German Pharmaceutical Society - Joint Meeting 2004 (DPhG 2004), 130
Poster
Steffen, Karasz, Thiele, Lengauer, Kämper, Wenz, Apostolakis
[-]
2007Combined similarity and QSPR virtual screening for guest molecules of $\beta$-cyclodextrin
In: New Journal of Chemistry [31], 1941-1949
Journal Article
Steffen, Thiele, Tietze, Strassnig, Kämper, Lengauer, Wenz, Apostolakis
[-]
2007Improved cyclodextrin-based receptors for camptothecin by inverse virtual screening
In: Chemistry [13], 6801-6809
Journal Article
Steijger, Abril, Engström, Kokocinski, Abril, Akerman, Alioto, Ambrosini, Antonarakis, Behr, Bohnert, Bucher, Cloonan, Derrien, Djebali, Du, Dudoit, Engström, Gerstein, Gingeras, Gonzalez, Grimmond, Habegger, Iseli, Jean, Kahles, Kokocinski, Lagarde, Leng, Lefebvre, Lewis, Mortazavi, Niermann, Rätsch, Reymond, Ribeca, Richard, Rougemont, Rozowsky, Sammeth, Sboner, Schulz, Searle, Solorzano, Solovyev, Stanke, Steijger, Stevenson, Stockinger, Valsesia, Weese, White, Wold, Wu, Wu, Zeller, Zerbino, Zhang, Hubbard, Guigó, Harrow, Bertone
[-]
2013Assessment of transcript reconstruction methods for RNA-seq
In: Nature Methods [10], 1177-84
Journal Article
Stöckel
[-]
2010History Based HIV Therapy Outcome Prediction
Universität des Saarlandes
Thesis - Masters thesis
Stöckel
[-]
2008Protein Surface Remeshing and Characterisation Using Morse-Smale Complexes
Universität des Saarlandes
Thesis - Bachelor thesis
Stohr, Roomp, Felbor, Weber
[Stohr, Felbor, Weber]
1995Genomic organization of the human tissue inhibitor of metalloproteinases-3 (TIMP3)
In: Genome Research [5], 483-7
Journal Article
Stoll, Corneliussen, Costello, Waetzig, Mellgard, Koch, Rosenstiel, Albrecht, Croucher, Seegert, Nikolaus, Hampe, Lengauer, Pierrou, Foelsch, Mathew, Lagerstrom-Fermer, Schreiber
[-]
2004Genetic variation in DLG5 is associated with inflammatory bowel disease
In: Nature Genetics [36], 376-380
Journal Article
Susser, Welsch, Wang, Zettler, Domingues, Karey, Hughes, Ralston, Tong, Herrmann, Zeuzem, Sarrazin
[-]
2009Characterization of resistance to the protease inhibitor boceprevir in hepatitis C virus-infected patients.
In: Hepatology [50], 1709-1718
Journal Article
Svichera, Centoa, Salpinia, Mercurioa, Fraune, Beggel, Hanc, Gorid, Wittkope, Bertolif, Michelig, Gubertinig, Longoh, Romanoh, Viscah, Gallinaroi, Marinoj, Mazzottaj, De Sanctisi, Fleurye, Trimoulete, Angelicoa, Cappielloh, Zhangc, Verheyenb, Ceccherini-Silbersteina, Pernoa
[-]
2011Role of hepatitis B virus genetic barrier in drug-resistance and immune-escape development
In: Digestive and Liver Disease [43], 975–983
Journal Article
Svicher, Ceccherini-Silberstein, Sing, Santoro, Gori, Beerenwinkel, Gago, D'Arrigo, Bellocchi, Giannella, Bertoli, D'Arminio Monforte, Antinori, Perno
[-]
2005Additional Mutations in HIV-1 Reverse Transcriptase are Involved in the Highly Ordered Regulation of NRTI Resistance
In: Proceedings of the 3rd European HIV Drug Resistance Workshop, -
Proceedings Article
Svicher, Ceccherini-Silberstein, Sing, Santoro, Gori, Beerenwinkel, Gago, D'Arrigo, Bellochi, Giannella, Bertoli, D'Arminio Monforte, Antinori, Perno
[-]
2005A highly ordered network of HIV-1 RT mutations regulates the continuous escape from antiviral drugs
In: International Workshop in HIV Dynamics and Evolution, -
Proceedings Article
Svicher, Cento, Salpini, Mercurio, Fraune, Beggel, Han, Gori, Wittkop, Bertoli, Micheli, Gubertini, Longo, Romano, Visca, Gallinaro, Marino, Mazzotta, De Sanctis, Fleury, Trimoulet, Angelico, Cappiello, Zhang, Verheyen, Ceccherini-Silberstein, Perno
[-]
2011Role of hepatitis B virus genetic barrier in drug-resistance and immune-escape development
In: Digestive and Liver Disease [43], 975-983
Journal Article
Svicher, Sing, Santoro, Forbici, Rodriguez- Barrios, Bertoli, Beerenwinkel, Bellocchi, Gago, d´Arminio Monforte, Antinori, Lengauer, Ceccherini-Silberstein, Perno
[-]
2006Involvement of novel HIV-1 reverse transcriptase mutations in the regulation of resistance to nucleoside inhibitors
In: Journal of Virology [80], 7186-7198
Journal Article
Swenson, Boehme, Thielen, McGovern, Harrigan
[-]
2010Genotypic determination of HIV-1 tropism in the clinical setting
In: HIV Therapy [4], 293-303
Journal Article
Swenson, Moores, Low, Thielen, Dong, Woods, Jensen, Wynhoven, Chan, Glascock, Harrigan
[-]
2010Improved detection of CXCR4-using HIV by V3 genotyping: application of population-based and "deep" sequencing to plasma RNA and proviral DNA
In: Journal of Acquired Immune Deficiency Syndromes [54], 506-510
Journal Article
Swenson, Mo, Dong, Zhong, Woods, Jensen, Thielen, Chapman, Lewis, James, Heera, Valdez, Harrigan
[-]
2011Deep Sequencing to Infer HIV-1 Co-Receptor Usage: Application to Three Clinical Trials of Maraviroc in Treatment-Experienced Patients
In: The Journal of Infectious Diseases [203], 237-245
Journal Article
Swenson, Mo, Dong, Zhong, Woods, Thielen, Jensen, Knapp, Chapman, Lewis, James, Heera, Valdez, Harrigan
[-]
2011Deep V3 sequencing for HIV type 1 tropism in treatment-naive patients: a reanalysis of the MERIT trial of maraviroc.
In: Clinical Infectious Diseases [53], 732-742
Journal Article
Takken, Albrecht, Tameling
[-]
2006Resistance proteins: molecular switches of plant defence
In: Current Opinion in Plant Biology [9], 383-390
Journal Article
Talwar
[-]
2008Development of Computational Methods for Metabolic Network Analysis based on Metabolomics Data
Universität des Saarlandes
Thesis - PhD thesis
Talwar, Lengauer, Rahnenführer, Heinzle, Velagapudi, Wittmann
[-]
2005Towards computational analysis of metabolic profiling data for protein function prediction.
In: Proceedings of the Yeast Systems Biology, 6th International Conference on Systems Biology (ICSB 2005), 1
Poster
Talwar, Lengauer, Rahnenführer, Velagapudi, Wittmann, Heinzle
[-]
2004Computational Methods For Metabolite Screening
In: Proceedings of the 12th International Conference on Intelligent Systems for Molecular Biology + 3rd European Conference on Computational Biology (ISMB/ECCB 2004), 1
Poster
Talwar, Lengauer, Rahnenführer, Velagapudi, Wittmann, Heinzle
[-]
2004Computational Methods For Metabolite Screening
In: Proceedings of the 5th International Conference on Systems Biology (ICSB 2004), 1
Poster
Talwar, Lengauer, Rahnenführer, Wittmann, Velagapudi, Heinzle
[-]
2005Computational Methods for Protein Function Prediction using Metabolomics Data
In: Proceedings of International Workshop on Systems Biology 2005, 1
Poster
Talwar, Lengauer, Wittmann, Mangadu, Heinzle
[-]
2003Towards cellular function through metabolite screening
In: Proceedings of the 3rd Annual Conference on Metabolic Profiling: Pathways in Discovery, 7
Proceedings Article
Talwar, Lengauer, Wittmann, Velagapudi, Heinzle
[-]
2006Development of Computational Methods for Analysis of Metabolic Profiling Data
In: Proceedings of International Conference on Systems Biology (ICSB 2006), Japan, 42-42
Proceedings Article
Talwar, Wittmann, Lengauer, Heinzle
[-]
2003Software tool for automated processing of 13C labeling data from mass spectrometry data
In: BioTechniques [35], 1214-1215
Journal Article
Tameling, Vossen, Albrecht, Lengauer, Berden, Haring, Cornelissen, Takken
[-]
2006Mutations in the NB-ARC domain of I-2 that impair ATP hydrolysis cause autoactivation
In: Plant Physiology [140], 1233-1245
Journal Article
Thielen
[-]
2011Genotypic Analysis of HIV-1 Coreceptor Usage
Universität des Saarlandes
Thesis - PhD thesis
Thielen
[-]
2006Prediction of linear B-cell epitopes and MHC class II binding peptides
Eberhardt-Karls-Universität Tübingen
Thesis - Masters thesis
Thielen, Altmann, Bogojeska, Kaiser, Lengauer
[-]
2009Estimating evolutionary pathways to 7CXCR4 usage from cross-sectional data
In: Abstracts presented at the XVIII International HIV Drug Resistance Workshop : Basic Principles & Clinical Implications, A16-A16
Poster
Thielen, Harrigan, Low, Moores, Altmann, Bozek, Heger, Sichtig, Kaiser, Lengauer
[-]
2008Improved genotypic prediction of HIV-1 coreceptor usage by incorporating V2 loop sequence variation
In: Antiviral Therapy, A100
Poster
Thielen, Kaiser, Lengauer
[-]
2008Improving HIV-1 coreceptor usage prediction from genotype with regions outside of V3
In: Reviews in Antiviral Therapy, 81-82
Poster
Thielen, Lengauer
[-]
2012Geno2pheno[454]: A Web Server for the Prediction of HIV-1 Coreceptor Usage from Next-Generation Sequencing Data
In: Intervirology [55], 113-117
Journal Article
Thielen, Lengauer, Harrigan, Swenson, Dong, McGovern, Lewis, James, Heera, Valdez
[-]
2010Mutations within GP41 are correlated with coreceptor tropism but do not substantially improve coreceptor usage prediction
In: Reviews in Antiviral Therapy & Infectious Diseases, 47-47
Poster
Thielen, Lengauer, Swenson, Dong, McGovern, Lewis, James, Heera, Valdez, Harrigan
[-]
2011Mutations in gp41 are correlated with coreceptor tropism but do not improve prediction methods substantially
In: Antiviral Therapy [16], 319-328
Journal Article
Thielen, Sichtig, Braun, Däumer, Walter, Noah, Wolf, Müller, Stürmer, Lengauer, Kaiser, Obermeier
[-]
2009Performance of genotypic coreceptor measurement using geno2pheno[coreceptor] in B- and non-B HIV subtypes in a large cohort of therapy-experienced patients in Germany
In: Reviews in Antiviral Therapy, 99-99
Poster
Thielen, Sichtig, Kaiser, Lam, Harrigan, Lengauer
[-]
2010Improved prediction of HIV-1 coreceptor usage with sequence information from the second hypervariable loop of gp120
In: Journal of Infectious Diseases [202], 1435-1443
Journal Article
Thornton, Bourne, Gilbert, Goble, Goldman, Gribskov, Hide, Higgins, Kanehisa, Lengauer, Linial, Myers, Quackenbush, Rebholz-Schuhmann, Rost, Sowdhamini, Valencia, Vingron, Xu (ed.)
(Ed: Thornton, Bourne, Gilbert, Goble, Goldman, Gribskov, Hide, Higgins, Kanehisa, Lengauer, Linial, Myers, Quackenbush, Rebholz-Schuhmann, Rost, Sowdhamini, Valencia, Vingron, Xu)
[Linial, Myers, Quackenbush, Rebholz-Schuhmann, Rost, Sowdhamini, Valencia, Vingron, Xu]
2004Proceedings Twelfth International Conference on Intelligent Systems for Molecular Biology/Third European Conference on Computional Biology 2004 (ISMB/ECCB 2004)Proceedings
Tolosi
[-]
2012Finding Regions of Aberrant DNA Copy Number Associated With Tumor Phenotype
Universität des Saarlandes
Thesis - PhD thesis
Tolosi
[-]
2006Analysis of Array CGH Data for the Estimation of Genetic Tumor Progression
Universität des Saarlandes
Thesis - Masters thesis
Tolosi, Lengauer
[-]
2011Classification with correlated features: unreliability of feature ranking and solutions
In: Bioinformatics [27], 1986-1994
Journal Article
Tolosi, Theißen, Halachev, Hero, Berthold, Lengauer
[-]
2013A method for finding consensus breakpoints in the cancer genome from copy number data
In: Bioinformatics [29], 1793-1800
Journal Article
Torda, Lengauer
[-]
2006Attachment IconEditorial: Selection of papers of the German Conference of Bioinformatics (GCB) 2005
In: Bioinformatics [22], 1
Journal Article
Trajkovski
[-]
2004Analysis of protein binding pocket flexibility
Universität des Saarlandes
Thesis - Masters thesis
Tress, Martelli, Frankish, Reeves, Wesselink, Yeats, Ólason, Albrecht, Hegyi, Giorgetti, Raimondo, Lagarde, Laskowski, López, Sadowski, Watson, Fariselli, Rossi, Nagy, Kai, Størling, Orsini, Assenov, Blankenburg, Huthmacher, Ramírez, Schlicker, Denoued, Jones, Kerrien, Orchard, Antonarakis, Reymond, Birney, Brunak, Casadio, Guigo, Harrow, Hermjakob, Jones, Lengauer, Orengo, Patthy, Thornton, Tramontano, Valencia
[-]
2007Attachment IconThe implications of alternative splicing in the ENCODE protein complement
In: Proceedings of the National Academy of Sciences [104], 5495-5500
Journal Article
Trignetti, Sing, Svicher, Santoro, Forbici, D'Arrigo, Bellocchi, Santoro, Marconi, Zaccarelli, Trotta, Bellagamba, Narciso, Antinori, Lengauer, Perno, Ceccherini-Silberstein
[-]
2009Dynamics of NRTI resistance mutations during therapy interruption
In: AIDS Research and Human Retroviruses [25], 57-64
Journal Article
Ulmschneider, Mueller-Vieira, Klein, Antes, Lengauer, Hartmann
[-]
2005Synthesis and Evaluation of Pyridylmethylene-tetrahydronaphthalenes and -indanes: Potent and Selective Inhibitors of Aldosterone Synthase (CYP11B2)
In: Journal of Medicinal Chemistry [48], 4489-4490
Journal Article
Ulmschneider, Mueller-Vieira, Mitrenga, Hartmann, Oberwinkler-Marchais, Klein, Bureik, Bernhardt, Antes, Lengauer
[-]
2005Synthesis and Evaluation of Imidazolylmethylenetetrahydronaphthalenes and Imidazolylmethyleneindanes: Potent Inhibitors of Aldosterone Synthase
In: Journal of Medicinal Chemistry [48], 1796-1805
Journal Article
Valentonyte, Hampe, Huse, Rosenstiel, Albrecht, Stenzel, Nagy, Gaede, Franke, Haesler, Koch, Lengauer, Seegert, Reiling, Ehlers, Schwinger, Platzer, Krawczak, Müller-Quernheim, Schürmann, Schreiber
[-]
2005Sarcoidosis is associated with a truncating splice site mutation in BTNL2
In: Nature Genetics [37], 357-364
Journal Article
Van Duist, Albrecht, Podswiadek, Giachino, Lengauer, Punzi, De Marchi
[-]
2005A new CARD15 mutation in Blau syndrome
In: European Journal of Human Genetics [13], 742-747
Journal Article
Van Ooijen, Mayr, Albrecht, Cornelissen, Takken
[-]
2008Transcomplementation, but not physical association of the CC-NB-ARC and LRR domains of tomato R protein Mi-1.2 is altered by mutations in the ARC2 subdomain
In: Molecular Plant [1], 401-410
Journal Article
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2008Structure-function analysis of the NB-ARC domain of plant disease resistance proteins
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2006Metabolic high- content screening of Saccharomyces cerevisiae reveals superior performance of single gene deletion strains
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2008Relevance of HIV gag cleavage site mutations in failures of protease inhibitor therapies
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2006Compensatory mutations at the HIV cleavage sites p7/p1 and p1/p6-gag in therapy-naive and therapy-experienced patients
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2005Heteroaryl-substituted naphthalenes and structurally modified derivatives: selective inhibitors of CYP11B2 for the treatment of congestive heart failure and myocardial fibrosis
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2006Synthesis and evaluation of heteroaryl substituted dihydronaphthalenes and indenes: potent and selective inhibitors of aldosterone synthase (CYP11B2) for the treatment of congestive heart failure and myocardial fibrosis
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Volkamer
[-]
2007Automated generation of pharmacophore type constraints to improve FlexX docking
Universität des Saarlandes
Thesis - Masters thesis
Volkamer
[-]
2005Attachment IconImplementation of a method to filter
out compounds with toxic, reactive
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Universität des Saarlandes
Thesis - Bachelor thesis
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[-]
2003Profile-Profile Alignment: A Powerful Tool For Protein Structure Prediction
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2008Structure to function
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[-]
2011Functional Profiling in Metagenomics
Universität des Saarlandes
Thesis - Masters thesis
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[-]
2009Using multidimensional Scaling for visualizing similarities of proteins
Universität des Saarlandes
Thesis - Bachelor thesis
Weinhold
[-]
2006Inference of Protein Function based on Functionally Conserved Regions in Sequence and Structure Space
Universität des Saarlandes
Thesis - Masters thesis
Weinhold, Sander, Domingues, Lengauer, Sommer
[-]
2008Attachment IconLocal function conservation in sequence and structure space
In: PLoS Computational Biology [4], e1000105
Journal Article
Weiss
[-]
2005Attachment IconGenerating Frequency Profiles from Multiple
Structure Alignments
Universität des Saarlandes
Thesis - Bachelor thesis
Weisser
[-]
2007Estimating the local variance of protein structure models
Universität des Saarlandes
Thesis - Masters thesis
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[-]
2010Only Slight Impact of Predicted Replicative Capacity for Therapy Response Prediction
In: PLoSOne [5], e9044,1-e9044,10
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2007Correlation nonstructural (NS)4B amino acid variations with initial viral kinetics during interferon-alpha-based therapy in HCV-1b-infected patients
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2010Dimerization of the hepatitis C virus nonstructural protein 4B depends on the integrity of an aminoterminal basic leucine zipper
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2011Comparison of Envelope 2 CD81 binding regions in PBMC-derived versus serum-derived hepatitis C virus isolates: higher conservation of CD81 region 2 in PBMC isolates
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2002Truncation mutations in ABCA1 suppress normal upregulation of full-length ABCA1 by 9-cis-retinoic acid and 22-R-hydroxycholesterol
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2007Structural and functional comparison of the non-structural protein 4B of flaviviridae
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Journal Article
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2008Attachment IconMolecular basis of telaprevir resistance due to V36 and T54 mutations in the NS3-4A protease of HCV
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2012Ketoamide Resistance and Hepatitis C Virus Fitness in Val55 Variants
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Journal Article
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2012Peptidomimetic Escape Mechanisms Arise via Genetic Diversity in the Ligand-Binding Site of the Hepatitis C Virus NS3/4A Serine Protease
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Journal Article
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2005Attachment IconPatients with high grade gliomas harboring delections of chromosomes 9p and 10q benefit from temozolomide treatment
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Journal Article
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2004Finite iteration DT-CNN with stationary templates
In: Proceedings of the 8th IEEE International Workshop on Cellular Neural Networks and their Applications (CNNA 2004), 459-464
Proceedings Article
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2010Partitioning biological data with transitivity clustering
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Journal Article
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[-]
2011Comprehensive cluster analysis with Transitivity Clustering
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Journal Article
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[-]
2010Efficient Online Transcription Factor Binding Site Adjustment by Integrating Transitive Graph Projection with MoRAine 2.0
In: Special Issue: 6th International Symposium on Integrative Bioinformatics, 117,1-117,11
Electronic Proceedings Article
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[-]
2011Extension and robustness of Transitivity Clustering for protein-protein interaction network analysis
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Journal Article
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2010Towards optimal alignment of protein structure distance matrices
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2003Tenofovir resistance and resensitization
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2012RRBSMAP: a fast, accurate and user-friendly alignment tool for reduced representation bisulfite sequencing
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2011RRBSMAP: A Fast, Accurate and User-friendly Alignment Tool for Reduced Representation Bisulfite Sequencing
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Yalak
[-]
2005Attachment IconAnalysis of Mutations in the Death Domains, Death Effector Domains, Caspase
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Universität des Saarlandes
Thesis - Bachelor thesis
Yamanishi, Pauwels, Saigo, Stovent
[-]
2011Extracting Sets of Chemical Substructures and Protein Domains Governing Drug-Target Interactions
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Journal Article
Yin
[-]
2005Model Selection for Mixtures of Mutagenetic Trees
Universität des Saarlandes
Thesis - Masters thesis
Yin, Beerenwinkel, Rahnenführer, Lengauer
[-]
2006Attachment IconModel Selection for Mixtures of Mutagenetic Trees
In: Statistical Applications in Genetics and Molecular Biology [5], Article 17
Journal Article
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2011Lung stem cell self-renewal relies on BMI1-dependent control of expression at imprinted loci
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Zanon, Rakovic, Blankenburg, Doncheva, Schwienbacher, Serafin, Alexa, Weichenberger, Albrecht, Klein, Hicks, Pramstaller, Domingues, Pichler
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2013Profiling of parkin-binding partners using tandem affinity purification
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Journal Article
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2007EuResist: exploration of multiple modeling techniques for prediction of response to treatment
In: Proceedings of the 5th European HIV Drug Resistance Workshop, -
Poster
Zazzi, Incardona, Rosen-Zvi, Prosperi, Lengauer, Altmann, Sonnerborg, Lavee, Schülter, Kaiser
[-]
2012Predicting Response to Antiretroviral Treatment by Machine Learning:
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Journal Article
Zazzi, Kaiser, Sönnerborg, Struck, Altmann, Prosperi, Rosen-Zvi, Petroczi, Peres, Schülter, Boucher, Brun-Vezinet, Harigan, Morris, Obermeier, Perno, Shafer, Vandamme, van Laethem, Wensing, Lengauer, Incardona
[-]
2010Prediction of Response to Antiretroviral Therapy by Human Experts and by the EuResist Data-Driven Expert System (the EVE Study)
In: HIV Medicine [Early View], 1-8
Electronic Journal Article
Zazzi, Kaiser, Sönnerborg, Struck, Altmann, Prosperi, Rosen-Zvi, Petroczi, Peres, Schülter, Boucher, Brun-Vezinet, Harrigan, Morris, Obermeier, Perno, Phanuphak, Pillay, Shafer, Vandamme, Van Laethem, Wensing, Lengauer, Incardona
[-]
2011Prediction of Response to Antiretroviral Therapy by Human Experts and by the EuResist Data-Driven Expert System (the EVE study)
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Journal Article
Zeidler
[-]
2012Cloudbasierte Analyse von viralen Sequenzdaten der neuesten Generation
Universität des Saarlandes
Thesis - Bachelor thesis
Zhang, Rohde, Tierling, Jurkowski, Bock, Santacruz, Ragozin, Reinhardt, Groth, Walter, Jeltsch
[-]
2009Attachment IconDNA methylation analysis of chromosome 21 gene promoters at single base pair and single allele resolution
In: PLoS Genetics [5], e1000438:1-e1000438:15
Electronic Journal Article
Zhu
[-]
2010Characterization, classification and alignment of protein-protein interfaces
Universität des Saarlandes
Thesis - PhD thesis
Zhu, Domingues, Sommer, Lengauer
[-]
2006NOXclass: prediction of protein-protein interaction types
In: BMC Bioinformatics [7], 1-15
Electronic Journal Article
Zhu, Domingues, Sommer, Lengauer
[-]
2005Analysis and prediction of protein-protein interaction types
In: 4th European Conference on Computational Biology (ECCB05), 1
Poster
Zhu, Sommer, Lengauer, Domingues
[-]
2008Attachment IconAlignment of Non-Covalent Interactions at Protein-Protein Interfaces
In: PLoS ONE [3], e1926
Journal Article
Zien, Aigner, Zimmer, Lengauer
[Zien, Aigner, Zimmer]
2001Centralization: A biologically sensible method for the normalization of gene expression data
In: Bioinformatics [17], 323S-331S
Journal Article
Zien, Fluck, Zimmer, Lengauer
(Ed: Myers, Hannenhalli, Istrail, Pevzner, Waterman)
[Zien, Fluck, Zimmer]
2002Microarrays: How Many Do You Need?
In: Proceedings of the Sixth Annual Conference on Research in Computational Molecular Biology (RECOMB2002), 321-330
Proceedings Article
Zien, Fluck, Zimmer, Lengauer
[-]
2003Microarrays: How many do you need?
In: Journal of Computational Biology [10], 653-667
Journal Article
Ziller, Gu, Müller, Donaghey, Tsai, Kohlbacher, De Jager, Rosen, Bennett, Bernstein, Gnirke, Meissner
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2013Charting a dynamic DNA methylation landscape of the human genome
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Journal Article
Ziller, Müller, Liao, Zhang, Gu, Bock, Boyle, Epstein, Bernstein, Lengauer, Gnirke, Meissner
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2011Genomic distribution and inter-sample variation of non-CpG methylation across human cell types
In: PLoS Genetics [17], e1002389,1-e1002389,15
Electronic Journal Article
Zimmer
[-]
2006Functional Site Scaffolds
Universität des Saarlandes
Thesis - Bachelor thesis
Zotenko, Mestre, O'Leary, Przytycka
[-]
2008Why Do Hubs in the Yeast Protein Interaction Network Tend To Be Essential: Reexamining the Connection between the Network Topology and Essentiality
In: PLoS Computational Biology [4], e1000140
Journal Article
Zwarts, Clee, Zwinderman, Engert, Singaraja, Loubser, James, Roomp, Hudson, Jukema, Kastelein, Hayden
[-]
2002ABCA1 regulatory variants influence coronary artery disease independent of effects on plasma lipid levels
In: Clinical Genetics [61], 115-125
Journal Article

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