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MPI-INF D3 Publications

MPI-INF D3 Publications

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#YearedocLckAuthor(s) [non member]Editor(s) [non member]TitleTypeedoc identifier
517
Hide details for Veröffentlichungen der MitarbeiterVeröffentlichungen der Mitarbeiter
2014Stop sign Icon[Eckel, Sandrah]
Baumbach, Jan
Hauschild, Anne-Christin
Stop sign IconOn the importance of statistics in breath analysis - Hope or curse?Unpublished/Draft935D41F50E66E6BEC1257C660055C7F3-Hauschild2014
2014[Maurer, Felix]
Hauschild, Anne-Christin
[Eisinger, Kathrin]
Baumbach, Jan
[Mayor, Arno]
[Baumbach, Jörg Ingo]
MIMA - A software for analyte identification in MCC/IMS chromatograms by mapping accompanying GC/MS measurements
In: International Journal for Ion Mobility Spectrometry [?], ?
Journal ArticleC62A51F90F56717DC1257C9700515A19-Hauschild2014a
2014Stop sign IconPironti, Alejandro
Lengauer, Thomas
Pfeifer, Nico
Stop sign IconSimulation of Sanger-sequencing errors in the context of genotypic tropism determination
In: Antiviral Therapy, A81
Poster34333C8CE5C70B6FC1257DA300336F9F-Pironti2013c
2014Stop sign IconPironti, Alejandro
Pfeifer, Nico
Kaiser, Rolf
Walter, Hauke
Lengauer, Thomas
Stop sign IconAccurate prediction of drug-exposure without using established drug-resistance mutations
In: Antiviral Therapy, A75
Poster9671E948877FF8C8C1257DA300346A5D-Pironti2013b
2014Stop sign IconPironti, Alejandro
Pfeifer, Nico
Kaiser, Rolf
Walter, Hauke
Lengauer, Thomas
Stop sign IconImproved HIV-1 drug-exposure reconstruction with linear support vector machines
In: Reviews in Antiviral Therapy & Infectious Diseases, 67
Poster320D8B754BF6B0A4C1257DA3003461DA-Pironti2013
2014Stop sign IconPironti, Alejandro
Pfeifer, Nico
[Kaiser, Rolf]
[Walter, Hauke]
Lengauer, Thomas
[Kippax, Susan]
[Sow, Papa Salif]
[Wainberg, Marc]
Stop sign IconImproved therapy-success prediction with GSS estimated from clinical HIV-1 sequences
In: Abstract Supplement of the HIV Drug Therapy Glasgow Congress 2014, 155
PosterC074477EC4FD9F53C1257DA3003446F6-Pironti2013d
2014Stop sign IconPironti, Alejandro
Pfeifer, Nico
Lengauer, Thomas
Stop sign IconAccurate prediction of drug-exposure without using established drug-resistance mutations
In: Antiviral Therapy, A75
Poster3EC1F4FAE60F2204C1257DA30032F553-Pironti2013b
2014Stop sign IconPironti, Alejandro
Pfeifer, Nico
Lengauer, Thomas
Stop sign IconImproved HIV-1 drug-exposure reconstruction with linear support vector machines
In: Reviews in Antiviral Therapy & Infectious Diseases, 67
Poster889E5EF314898D50C1257DA300325876-Pironti2013
2014Stop sign IconPironti, Alejandro
Sierra, Saleta
Kaiser, Rolf
Lengauer, Thomas
Pfeifer, Nico
Stop sign IconSimulation of Sanger-sequencing errors in the context of genotypic tropism determination
In: Antiviral Therapy, A81
PosterA34461E921B1F888C1257DA3003457FC-Pironti2013c
2014[Smolinska, Agnieszka]
Hauschild, Anne-Christin
[Fijten, Rianne]
[Dallinga, Jan]
Baumbach, Jan
[van Schooten, Frederik]
Current breathomics – A review on data pre-processing techniques and machine learning in metabolomics breath analysisUnpublished/Draft962AD4012680C6FAC1257C6600568C94-Hauschild2014
2013Stop sign IconBeggel, Bastian
[Münk, C.]
[Däumer, M.]
[Hauck, K.]
[Häussinger, D.]
Lengauer, Thomas
[Ehrhardt, A.]
Stop sign IconFull genome ultra-deep pyrosequencing associates G-to-A-hypermutation of the hepatitis B virus genome with the natural progression of hepatitis B
In: Journal of Viral Hepatitis [12], 882-889
Journal ArticleE5B67F4DBA747F50C1257C0B00359108-lengauer2013k
2013Stop sign Icon[Bhadra, T.]
[Battacharya, M.]
[Feuerbach, L.]
Lengauer, Thomas
Bandyopadhyay, S.
Stop sign IconDNA Methylation Patterns Facilitate the Identification of Transcription Start Sites: A Brain-specofoc Study
In: PLOSONE [8], xx
Journal Article43F7490EA03DDC21C1257C0B00351960-lengauer2013j
2013Stop sign Icon[Bozek, K.]
Lengauer, Thomas
[Sierra, S.]
[Kaiser, Rolf]
[Domingues, F.S.]
Stop sign IconAnalysis of physicochemical and structural properties determining HIV-1 coreceptor usage
In: PLoS Computational Biology [x], x
Journal ArticleA15B25110B236E58C1257AD3004DB1C1-lengauer2012g
2013[Dietz, J.]
Schelhorn, Sven-Eric
[Fitting, D.]
[Mihm, U.]
[Susser, S.]
[Welker, M.-W.]
[Füller, C.]
[Däumer, M.]
[Teuber, G.]
[Wedemeyer, H.]
[Berg, T.]
Lengauer, Thomas
[Z., Stefan]
[Herrmann, E.]
[Sarrazin, C.]
Deep sequencing reveals mutagenic effects of ribavirin during monotherapy of HCV genotype 1-infected patients
In: Journal of Virology [87], 6172-6181
Journal Article14C01737FFEEBB1BC1257C0B0032E872-lengauer2013h
2013[Ellinghaus, David]
[Zhang, Hu]
[Zeissig, Sebastian]
[Lipinski, Simone]
[Till, Andreas]
[Jiang, Tao]
[Stade, Björn]
[Bromberg, Yana]
[Ellinghaus, Eva]
[Keller, Andreas]
[Rivas, Manuel A.]
[Skieceviciene, Jurgita]
Doncheva, Nadezhda T.
[Liu, Xiao]
[Liu, Qing]
[Jiang, Fuman]
[Forster, Michael]
Mayr, Gabriele
Albrecht, Mario
[Häsler, Robert]
[Boehm, Bernhard O.]
[Goodall, Jane]
[Berzuini, Carlo R.]
[Lee, James]
[Andersen, Vibeke]
[Vogel, Ulla]
[Kupcinskas, Limas]
[Kayser, Manfred]
[Krawczak, Michael]
[Nikolaus, Susanna]
[Weersma, Rinse K.]
[Ponsioen, Cyriel Y.]
[Sans, Miquel]
[Wijmenga, Cisca]
[Strachan, David P.]
[McArdle, Wendy L.]
[Vermeire, Séverine]
[Rutgeerts, Paul]
[Sanderson, Jeremy D.]
[Mathew, Christopher G.]
[Vatn, Morten H.]
[Wang, Jun]
[Nöthen, Markus M.]
[Duerr, Richard H.]
[Büning, Carsten]
[Brand, Stephan]
[Glas, Jürgen]
[Winkelmann, Juliane]
[Illig, Thomas]
[Latiano, Anna]
[Annese, Vito]
[Halfvarson, Jonas]
[D'Amato, Mauro]
[Daly, Mark J.]
[Nothnagel, Michael]
[Karlsen, Tom H.]
[Subramani, Suresh]
[Rosenstiel, Philip]
[Schreiber, Stefan]
[Parkes, Miles]
[Franke, Andre]
Association between variants of PRDM1 and NDP52 and Crohn's disease, based on exome sequencing and functional studies
In: Gastroenterology [145], 339-347
Journal ArticleD94481A97C347AB5C1257C70004CF69C-Albrecht2013b
2013Stop sign IconHalachev, Konstantin
Bast, H.
Lengauer, Thomas
Bock, Christoph
Stop sign IconInteractive exploration of large genome and epigenome datasets in real time
In: Genome Biology [13], xx
Journal ArticleCB75816DF52499BBC1257C0B0030F775-lengauer2013f
2013Hauschild, Anne-Christin
[Baumbach, Joerg Ingo]
Baumbach, Jan
Attachment IconPaving the Way for Automated Clinical Breath Analysis and Biomarker DetectionMiscellaneous01BED1CA756B7F8FC1257C6600542893-Hauschild2013b
2013Kacprowski, Tim
Doncheva, Nadezhda T.
Albrecht, Mario
Attachment IconNetworkPrioritizer: a versatile tool for network-based prioritization of candidate disease genes or other molecules
In: Bioinformatics [29], 1471-1473
Journal Article01CE323C97D6DDB6C1257C60005071DC-Albrecht2013d
2013Stop sign IconKalaghatgi, Prabhav
Lawyer, Glenn
Stop sign IconInter-country mixing in HIV transmission clusters: a pan-European phylodynamics study
In: Abstract Book 11th European HIV & Hepatitis Workshop, 9
Poster893733FC0B2A8D2DC1257C82004F1600-Kalaghatgi2013
2013Kalinina, Olga
Pfeifer, Nico
Lengauer, Thomas
Modelling binding between CCR5 and CXCR4 receptors and their ligands suggests the surface electrostatic potential of the co-receptor to be a key player in the HIV-1 tropism
In: Retrovirology [10], 130
Journal Article9D600A85819064AEC1257C6A00543F15-Kalinina2013
2013[Le, Hai-Son]
Schulz, Marcel Holger
[McCauley, Brenna MM]
[Hinman, Veronica F]
[Bar-Joseph, Ziv]
Probabilistic error correction for RNA sequencing
In: Nucleic Acids Researcb [41], e109
Journal ArticleE6759A958E533164C1257C6900594543-SchulzA2013
2013[Liu, Jimmy Z.]
[Hov, Johannes Roksund]
[Folseraas, Trine]
[Ellinghaus, Eva]
[Rushbrook, Simon M.]
Doncheva, Nadezhda T.
[Andreassen, Ole A.]
[Weersma, Rinse K.]
[Weismuller, Tobias J.]
[Eksteen, Bertus]
[Invernizzi, Pietro]
[Hirschfield, Gideon M.]
[Gotthardt, Daniel Nils]
[Pares, Albert]
[Ellinghaus, David]
[Shah, Tejas]
[Juran, Brian D.]
[Milkiewicz, Piotr]
[Rust, Christian]
[Schramm, Christoph]
[Muller, Tobias]
[Srivastava, Brijesh]
[Dalekos, Georgios]
[Nothen, Markus M.]
[Herms, Stefan]
[Winkelmann, Juliane]
[Mitrovic, Mitja]
[Braun, Felix]
[Ponsioen, Cyriel Y.]
[Croucher, Peter J. P.]
[Sterneck, Martina]
[Teufel, Andreas]
[Mason, Andrew L.]
[Saarela, Janna]
[Leppa, Virpi]
[Dorfman, Ruslan]
[Alvaro, Domenico]
[Floreani, Annarosa]
[Onengut-Gumuscu, Suna]
[Rich, Stephen S.]
[Thompson, Wesley K.]
[Schork, Andrew J.]
[Naess, Sigrid]
[Thomsen, Ingo]
Mayr, Gabriele
[Konig, Inke R.]
[Hveem, Kristian]
[Cleynen, Isabelle]
[Gutierrez-Achury, Javier]
[Ricano-Ponce, Isis]
[van Heel, David]
[Bjornsson, Einar]
[Sandford, Richard N.]
[Durie, Peter R.]
[Melum, Espen]
[Vatn, Morten H.]
[Silverberg, Mark S.]
[Duerr, Richard H.]
[Padyukov, Leonid]
[Brand, Stephan]
[Sans, Miquel]
[Annese, Vito]
[Achkar, Jean-Paul]
[Boberg, Kirsten Muri]
[Marschall, Hanns-Ulrich]
[Chazouilleres, Olivier]
[Bowlus, Christopher L.]
[Wijmenga, Cisca]
[Schrumpf, Erik]
[Vermeire, Severine]
Albrecht, Mario
[The UK-PSCSC Consortium,]
[The International IBD Genetics Consortium,]
[Rioux, John D.]
[Alexander, Graeme]
[Bergquist, Annika]
[Cho, Judy]
[Schreiber, Stefan]
[Manns, Michael P.]
[Farkkila, Martti]
[Dale, Anders M.]
[Chapman, Roger W.]
[Lazaridis, Konstantinos N.]
[The International PSC Study Group,]
[Franke, Andre]
[Anderson, Carl A.]
[Karlsen, Tom H.]
Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis
In: Nature Genetics [45], 670-677
Journal Article10209969026DD7EDC1257C70004C724B-Albrecht2013a
2013Stop sign Icon[Neumann-Fraune, Maria]
Beggel, Bastian
[Pfister, Herbert]
[Kaiser, Rolf]
[Verheyen, Jens]
Stop sign IconHigh frequency of complex mutational patterns in lamivudine resistant hepatitis B virus isolates
In: Journal of Medical Virology [200], 39-49
Journal Article61B3D93A7F39323CC1257AFD00381E52-Beggel2013a
2013Stop sign IconPfeifer, Nico
Lengauer, Thomas
Stop sign IconAssociation Between HIV-1 Coreceptor Usage and Resistance to Some Broadly Neutralizing Antibodies
In: Proceedings of the AIDS Vaccine Conference 2013, A-1-A-208
PosterEEE62E1144F8CC8BC1257C6A0055F9A3-PfeiferLengauer2013
2013Pironti, AlejandroHIV-1 fitness landscape models for indinavir treatment pressure using observed evolution in longitudinal sequence data are predictive for treatment failure
In: Infection, Genetics and Evolution [19], 349–360
Journal Article617103D78A5E4215C1257C6A004E1E2B-Pironti2013
2013Stop sign IconPironti, Alejandro
Lengauer, Thomas
Pfeifer, Nico
Stop sign IconEffects of sequencing errors on geno2pheno[coreceptor] predictions
In: Abstract Book 11th European Meeting on HIV & Hepatitis, 23-24
PosterE65A7D34540A5DBAC1257C6A004EF397-Pironti2013
2013Stop sign IconPironti, Alejandro
Lengauer, Thomas
Pfeifer, Nico
Stop sign IconIn silico analysis of the effects of sequencing errors on geno2pheno[coreceptor]
In: Abstract Book of the International Workshop on HIV&Hepatitis Virus, A142
PosterC79B1849D90C0A33C1257C6A004EA3D3-Pironti2013
2013[Radivojac, Predrag]
[Clark, Wyatt T]
[Oron, Tal Ronnen]
[Schnoes, Alexandra M]
[Wittkop, Tobias]
[Sokolov, Artem]
[Graim, Kiley]
[Funk, Christopher]
[Verspoor, Karin]
[Ben-Hur, Asa]
[Pandey, Gaurav]
[Yunes, Jeffrey M]
[Talwalkar, Ameet S]
[Repo, Susanna]
[Souza, Michael L]
[Piovesan, Damiano]
[Casadio, Rita]
[Wang, Zheng]
[Cheng, Jianlin]
[Fang, Hai]
[Gough, Julian]
[Koskinen, Patrik]
[T\"{o}r\"{o}nen, Petri]
[Nokso-Koivisto, Jussi]
[Holm, Liisa]
[Cozzetto, Domenico]
[Buchan, Daniel W A]
[Bryson, Kevin]
[Jones, David T]
[Limaye, Bhakti]
[Inamdar, Harshal]
[Datta, Avik]
[Manjari, Sunitha K]
[Joshi, Rajendra]
[Chitale, Meghana]
[Kihara, Daisuke]
[Lisewski, Andreas M]
[Erdin, Serkan]
[Venner, Eric]
[Lichtarge, Olivier]
[Rentzsch, Robert]
[Yang, Haixuan]
[Romero, Alfonso E]
[Bhat, Prajwal]
[Paccanaro, Alberto]
[Hamp, Tobias]
[Ka\ss ner, Rebecca]
[Seemayer, Stefan]
[Vicedo, Esmeralda]
[Schaefer, Christian]
[Achten, Dominik]
[Auer, Florian]
[Boehm, Ariane]
[Braun, Tatjana]
[Hecht, Maximilian]
[Heron, Mark]
[H\"{o}nigschmid, Peter]
[Hopf, Thomas A]
[Kaufmann, Stefanie]
[Kiening, Michael]
[Krompass, Denis]
[Landerer, Cedric]
[Mahlich, Yannick]
[Roos, Manfred]
[Bj\"{o}rne, Jari]
[Salakoski, Tapio]
[Wong, Andrew]
[Shatkay, Hagit]
Gatzmann, Fanny
Sommer, Ingolf
[Wass, Mark N]
[Sternberg, Michael J E]
[Skunca, Nives]
[Supek, Fran]
[Bo\v{s}njak, Matko]
[Panov, Pan\v{c}e]
[D\v{z}eroski, Sa\v{s}o]
[Smuc, Tomislav]
[Kourmpetis, Yiannis A I]
[van Dijk, Aalt D J]
[Braak, Cajo J F Ter]
[Zhou, Yuanpeng]
[Gong, Qingtian]
[Dong, Xinran]
[Tian, Weidong]
[Falda, Marco]
[Fontana, Paolo]
[Lavezzo, Enrico]
[{Di Camillo}, Barbara]
[Toppo, Stefano]
[Lan, Liang]
[Djuric, Nemanja]
[Guo, Yuhong]
[Vucetic, Slobodan]
[Bairoch, Amos]
[Linial, Michal]
[Babbitt, Patricia C]
[Brenner, Steven E]
[Orengo, Christine]
[Rost, Burkhard]
[Mooney, Sean D]
[Friedberg, Iddo]
A large-scale evaluation of computational protein function prediction
In: Nature Methods [10], 221-227
Journal Article0B86C9EE091302D1C1257B47005C687E-Sommer2013
2013[Röttger, Richard]
Kalaghatgi, Prabhav
[Sun, Peng]
[de Castro Soares, Siomar]
[Azevedo, Vasco]
[Wittkop, Tobias]
[Baumbach, Jan]
Density Parameter Estimation for Finding Clusters of Homologous Proteins - Tracing Actinobacterial Pathogenicity Life Styles
In: Bioinformatics [29], 215-222
Journal Article30B0AE29B59422D6C1257AEE005D0C44-roettger2012density
2013[Sandoval, Juan]
[Mendez-Gonzales, Jesus]
[Nadal, Ernest]
[Chen, Guoan]
[Carmona, F. Javier]
[Sayols, Sergi]
[Moran, Sebastian]
[Heyn, Holger]
[Vizoso, Miguel]
[Gomez, Antonio]
[Sanchez-Cespedes, Montse]
Assenov, Yassen
Müller, Fabian
Bock, Christoph
[Taron, Miquel]
[Mora, Josefina]
[Muscarella, Lucia A.]
[Liloglou, Triantafillos]
[Davies, Michael]
[Pollan, Marina]
[Pajares, Maria J.]
[Torre, Wenceslao]
[Montuenga, Luis M.]
[Brambilla, Elisabeth]
[Field, John K.]
[Roz, Luca]
[Lo Iacono, Marco]
[Scagliotti, Giorgio V.]
[Rosell, Rafael]
[Beer, David G.]
[Esteller,Manel]
A Prognostic DNA Methylation Signature for Stage I Non-Small-Cell Lung Cancer
In: Journal of Clinical Oncology [31], 4140-4147
Journal ArticleD1543BC91BBA782EC1257C60005FF511-Sandoval2013
2013Schelhorn, Sven-Eric
[Fischer, M.]
[Tolosi, Laura]
[Altmüller, J.]
[Nürnberg, P.]
[Pfister, H.]
Lengauer, Thomas
Berthold, F.
Sensitive detection of viral transcripts in human tumor transcriptomes
In: PLOS Computational Biology [9], xx
Journal Article6C70D4D0F211A917C1257C0B00368971-lengauer2013m
2013Schulz, Marcel Holger
[Pandit, Kusum V]
[Lino Cardenas, Christian L]
[Ambalavanan,Namasivayam]
[Kaminski, Naftali]
[Bar-Joseph, Ziv]
Reconstructing dynamic microRNA-regulated interaction networks
In: Proceedings of the National Academy of Sciences of the United States [110], 15686–15691
Journal Article55C8FAC893CDA486C1257C6A004EC097-SchulzB2013
2013[Simmer, F.]
[Brinkmann, A.B.]
Assenov, Yassen
[Matarese, F.]
[Kaan, A.]
Lengauer, Thomas
Bock, Christoph
[Colantuoni, V.]
[Altucci, L.]
[Stunnenberg, H.G.]
Comparative genome-wide DNA methylation analysis of colorectal tumor and matched human tissue
In: Epigenetics [7], 1355-1367
Journal Article30EA1F1D4DE1764CC1257C0B003221D4-lengauer2013g
2013[Steijger, T]
[Abril, JF]
[Engström,PG]
[Kokocinski, F]
[Abril, JF]
[Akerman, M]
[Alioto, T]
[Ambrosini, G]
[Antonarakis, SE]
[Behr, J]
[Bohnert, R]
[Bucher, P]
[Cloonan, N]
[Derrien, T]
[Djebali, S]
[Du, J]
[Dudoit, S]
[Engström, PG]
[Gerstein, M]
[Gingeras, TR]
[Gonzalez, D]
[Grimmond, SM]
[Habegger, L]
[Iseli, C]
[Jean, G]
[Kahles, A]
[Kokocinski, F]
[Lagarde, J]
[Leng, J]
[Lefebvre, G]
[Lewis, S]
[Mortazavi, A]
[Niermann, P]
[Rätsch, G]
[Reymond, A]
[Ribeca, P]
[Richard, H]
[Rougemont, J]
[Rozowsky, J]
[Sammeth, M]
[Sboner, A]
Schulz, Marcel Holger
[Searle, SM]
[Solorzano, ND]
[Solovyev, V]
[Stanke, M]
[Steijger, T]
[Stevenson, BJ]
[Stockinger, H]
[Valsesia, A]
[Weese, D]
[White, S]
[Wold, BJ]
[Wu, J]
[Wu, TD]
[Zeller, G]
[Zerbino, D]
[Zhang, MQ]
[Hubbard, TJ]
[Guigó, R]
[Harrow, J]
[Bertone, P]
Assessment of transcript reconstruction methods for RNA-seq
In: Nature Methods [10], 1177-84
Journal Article75F13D2139AD2478C1257C6A004F9484-SchulzC2013
2013Tolosi, Laura
[Theißen, J.]
Halachev, Konstantin
[Hero, B.]
[Berthold, F.]
Lengauer, Thomas
A method for finding consensus breakpoints in the cancer genome from copy number data
In: Bioinformatics [29], 1793-1800
Journal ArticleB1C8C34D9C5C30ACC1257C0B0036298B-lengauer2013l
2013[Zanon, Alessandra]
[Rakovic, Aleksandar]
[Blankenburg, Hagen]
Doncheva, Nadezhda T.
[Schwienbacher, Christine]
[Serafin, Alice]
Alexa, Adrian
[Weichenberger, Christian X.]
Albrecht, Mario
[Klein, Christine]
[Hicks, Andrew A.]
[Pramstaller, Peter P.]
[Domingues, Francisco S.]
[Pichler, Irene]
Profiling of parkin-binding partners using tandem affinity purification
In: PLoS ONE [8], 1-17
Journal Article348090E858FCD2E4C1257C70004DB8FD-Albrecht2013c
2013[Ziller, Michael J.]
[Gu, Hongcang]
Müller, Fabian
[Donaghey, Julie]
[Tsai, Linus T.-Y.]
[Kohlbacher, Oliver]
[De Jager, Philip L.]
[Rosen, Evan D.]
[Bennett, David A.]
[Bernstein, Bradley E.]
[Gnirke, Andreas]
[Meissner, Alexander]
Charting a dynamic DNA methylation landscape of the human genome
In: Nature [500], 477–481
Journal Article6CAEAA3794FDEA3BC1257C6000605839-Ziller2013
2012[Adams, David]
[Altucci, Lucia]
[Antonarakis, Stylianos E]
[Ballesteros, Juan]
[Beck, Stephan]
[Bird, Adrian]
Bock, Christoph
[Boehm, Bernhard]
[Campo, Elias]
[Caricasole, Andrea]
[Dahl, Fredrik]
[Dermitzakis, Emmanouil T]
[Enver, Tariq]
[Esteller, Manel]
[Estivill, Xavier]
[Ferguson-Smith, Anne]
[Fitzgibbon, Jude]
[Flicek, Paul]
[Giehl, Claudia]
[Graf, Thomas]
[Grosveld, Frank]
[Guigó, Roderic]
[Gut, Ivo]
[Helin, Kristian]
[Jarvius, Jonas]
[Küppers, Ralf]
[Lehrach, Hans]
Lengauer, Thomas
[Lernmark, Åke]
[Leslie, David]
[Loeffler, Markus]
[Macintyre, Elizabeth]
[Mai, Antonello]
[Martens, Joost H A]
[Minucci, Saverio]
[Ouwehand, Willem H]
[Pelicci, Pier Giuseppe]
[Pendeville, Hèléne]
[Porse, Bo]
[Rakyan, Vardhman]
[Reik, Wolf]
[Schrappe, Martin]
[Schübeler, Dirk]
[Seifert, Martin]
[Siebert, Reiner]
[Simmons, David]
[Soranzo, Nicole]
[Spicuglia, Salvatore]
[Stratton, Michael]
[Stunnenberg, Hendrik G]
[Tanay, Amos]
[Torrents, David]
[Valencia, Alfonso]
[Vellenga, Edo]
[Vingron, Martin]
[Walter, Jörn]
[Willcocks, Spike]
BLUEPRINT to decode the epigenetic signature written in blood
In: Nature Biotechnology [30], 224-226
Journal Article9989EDB3AC4E86A0C1257B02002F3253-Adams2012
2012Alcaraz, Nicolas
Kucuk, Hande
[Weile, Jochen]
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Universität des Saarlandes
Thesis - Bachelor thesisC57116B0CD2838E7C1257834003CABD2-Gatzmann2010a
2010[Gu, Hongcang]
Bock, Christoph
[Mikkelsen, Tarjei S.]
[Jäger, Natalie]
[Smith, Zachary D.]
[Tomazou, Eleni]
[Gnirke, Andreas]
[Lander, Eric S.]
[Meissner, Alexander]
Attachment IconGenome-scale DNA methylation mapping of clinical samples at single-nucleotide resolution
In: Nature Methods [7], 133-136
Journal ArticleE833A5BFCF6FA3DEC12578180070CC67-GuBock2010
2010[Harris, R. Alan]
[Wang, Ting]
[Coarfa, Cristian]
[Nagarajan, Raman P.]
[Hong, Chibo]
[Downey, Sara L.]
[Johnson, Brett E.]
[Fouse, Shaun D.]
[Delaney, Allen]
[Zhao, Yongjun]
[Olshen, Adam]
[Ballinger, Tracy]
[Zhou, Xin]
[Forsberg, Kevin J.]
[Gu, Junchen]
[Echipare, Lorigail]
[O'Geen, Heriette]
[Lister, Ryan]
[Pelizzola, Mattia]
[Xi, Yuanxin]
[Epstein, Charles B.]
[Bernstein, Bradley E.]
[Hawkins, R. David]
[Ren, Bing]
[Chung, Wen-Yu]
[Gu, Hongcang]
Bock, Christoph
[Gnirke, Andreas]
[Zhang, Michael Q.]
[Haussler, David]
[Ecker, Joseph R.]
[Li, Wei]
[Farnham, Peggy J.]
[Waterland, Robert a.]
[Meissner, Alexander]
[Marra, Marco A.]
[Hirst, Martin]
[Milosavljevic, Aleksandar]
[Costello, Joseph F.]
Comparison of sequencing-based methods to profile DNA methylation and identification of monoallelic epigenetic modifications
In: Nature Biotechnology [28], 1097-1105
Journal Article0648E026BF9E11A7C12578180071A2F2-Harris2010
2010Kacprowski, TimAnalysis of protein complexes and tissue-spedific expression
Universität des Saarlandes
Thesis - Bachelor thesisB4BCE6B8C551A688C1257834003C7821-Kacprowski2010a
2010König, EvaEnv-wide analysis of coreceptor determining sites and subtype-specific differences in HIV-1
Universität des Saarlandes
Thesis - Bachelor thesis6ECCCB669C8526F6C1257834003C90B7-König2010a
2010[Lange, Christian Markus]
Roomp, Kirsten
[Dragan, Anette]
[Nattermann, Jacob]
[Michalk, Monika]
[Spengler, Ulrich]
[Weich, Viola]
Lengauer, Thomas
[Zeuzem, Stefan]
[Berg, Thoma]
[Sarrazin, Christoph]
HLA class I allele associations with HCV genetic variants in patients with chronic HCV genotypes 1a or 1b infection
In: Journal of Hepatology [53], 1022-1028
Journal ArticleC69F4B7D49F888A4C125781600407FB9-RoompLengauer2010b
2010Lengauer, Thomas
Altmann, André
Thielen, Alexander
[Kaiser, Rolf]
Chasing the AIDS Virus
In: Communications of the ACM [53], 66-74
Journal Article0E40FB8CA35DB75AC12577AE004B77EC-Lengauer2010a
2010[McGovern, Rachel A]
Thielen, Alexander
[Mo, Theresa]
[Dong, Winnie]
[Woods, Conan K]
[Chapman, Douglass]
[Lewis, Marilyn]
[James, Ian]
[Heera, Jayvant]
[Valdez, Hernan]
[Harrigan, P Richard]
Population-based V3 genotypic tropism assay: a retrospective analysis using screening samples from the A4001029 and MOTIVATE studies
In: AIDS [24], 2517-2525
Journal ArticleB2FB261FE4334D29C12577F8003F5A18-McGovern2010
2010[Mihm, Ulrike]
[Hofmann, W.P.]
Welsch, Christoph
[Polta, A.]
Lengauer, Thomas
[Zeuzem, Stefan]
[Sarrazin, Christoph]
[Herrmann, E.]
Effect of ribavirin on the frequency of RNAse L cleavage sites within the hepatitis C viral genome
In: Journal of Viral Hepatitis [17], 217-221
Journal Article44C3F1A370199AA8C1257815004F445D-lengauerwelsch2010
2010Ramírez, Fidel
Albrecht, Mario
Finding scaffold proteins in interactomes
In: Trends in Cell Biology [20], 2-4
Journal Article3AFEEED14604C277C12576A8004DABDF-Albrecht2010b
2010Ramirez, Fidel[Gomez Merino, Fernando Carlos]
[Silva Rojas, Hilda Victoria]
[Pérez Rodríguez, Paulino]
Tutorial Cytoscape
In: Bioinformática: Aplicaciones a la genómica y proteómica, 73-98
Part of a BookA1F8029E7D5EE544C12578A700340831-Ramirez2010
2010[Rhee, Soo-Yon]
[Margeridon-Thermet, Severin]
[Nguyen, Mindie]
[Liu, Tommy]
[Kagan, Ron]
Beggel, Bastian
[Verheyen, Jens]
[Kaiser, Rolf]
[Shafer, Robert]
Attachment IconHepatitis B virus reverse transcriptase sequence variant database for sequence analysis and mutation discovery
In: Antiviral Research [88], 269-275
Journal Article0C60170AB82A5380C12578000043E8AE-Rhee2010
2010Schlicker, Andreas
Albrecht, Mario
FunSimMat update: new features for exploring functional similarity
In: Nucleic Acids Research [38], D244-D248
Journal ArticleDAF511CF50801FB1C12576A8004D6C05-Albrecht2010a
2010Schlicker, Andreas
Lengauer, Thomas
Albrecht, Mario
Improving disease gene prioritization using the semantic similarity of Gene Ontology terms
In: Bioinformatics [26], i561-i567
Journal Article888B9754E93E7CBEC12577AE004A6B9F-Albrecht2010d
2010Speicher, Nora K.Network analysis of viral host factors
Universität des Saarlandes
Thesis - Bachelor thesis81AACB94EC04F78EC125783400398AD7-Speicher2010
2010[Swenson, Luke C.]
[Boehme‌, Richard]
Thielen, Alexander
[McGovern‌, Rachel A.]
[Harrigan, P. Richard]
Genotypic determination of HIV-1 tropism in the clinical setting
In: HIV Therapy [4], 293-303
Journal Article93B58E5C9242B82BC12577F800471EE8-Swenson2010a
2010[Swenson, Luke C.]
[Moores, Andrew]
[Low, Andrew J.]
Thielen, Alexander
[Dong, Winnie]
[Woods, Conan]
[Jensen, Mark A.]
[Wynhoven, Brian]
[Chan, Dennison]
[Glascock, Christopher]
[Harrigan, P. Richard]
Improved detection of CXCR4-using HIV by V3 genotyping: application of population-based and "deep" sequencing to plasma RNA and proviral DNA
In: Journal of Acquired Immune Deficiency Syndromes [54], 506-510
Journal Article264BFB2B4B6934CBC12577F800465B9C-Swenson2010
2010Stop sign IconThielen, Alexander
Lengauer, Thomas
[Harrigan, P Richard]
[Swenson, Luke]
[Dong, Winnie WY]
[McGovern, Rachel A]
[Lewis, Marilyn]
[James, Ian]
[Heera, Jayvant]
[Valdez, Hernan]
Stop sign IconMutations within GP41 are correlated with coreceptor tropism but do not substantially improve coreceptor usage prediction
In: Reviews in Antiviral Therapy & Infectious Diseases, 47-47
Poster4F1FE15C287FC3D4C12577A6002DAF29-Thielen2010EDRW
2010Thielen, Alexander
[Sichtig, Nadine]
[Kaiser, Rolf]
[Lam, Jeffrey]
[Harrigan, P. Richard]
Lengauer, Thomas
Improved prediction of HIV-1 coreceptor usage with sequence information from the second hypervariable loop of gp120
In: Journal of Infectious Diseases [202], 1435-1443
Journal ArticleA5D528631A982D6FC12577F8003DB985-Thielen2010
2010[Welker, Martin-Walter]
[Welsch, Christoph]
[Meyer, Aline]
Antes, Iris
Albrecht, Mario
[Forestier, Nicole]
[Kronenberger, Bernd]
Lengauer, Thomas
[Piiper, Albrecht]
[Zeuzem, Stefan]
[Sarrazin, Christoph]
Dimerization of the hepatitis C virus nonstructural protein 4B depends on the integrity of an aminoterminal basic leucine zipper
In: Protein Science [19], 1327-1336
Journal Article89DF0070658FEC7AC1257753004D5D13-Albrecht2010e
2010[Wittkop, Tobias]
Emig, Dorothea
[Lange, Sita]
[Rahmann, Sven]
Albrecht, Mario
[Morris, John H.]
[Böcker, Sebastian]
[Stoye, Jens]
Baumbach, Jan
Partitioning biological data with transitivity clustering
In: Nature Methods [7], 419-420
Journal ArticleFC4922CF38BD83EFC1257753004A9685-Wittkop2010
2010[Wohlers, Inken]
Domingues, Francisco S.
[Klau, Gunnar W.]
Towards optimal alignment of protein structure distance matrices
In: Bioinformatics [26], 2273-2280
Journal Article73BDC324043F9E79C12577E7003F663C-Wohlers2010
2009Adams, Ben
McHardy, Alice
[Lundegaard, C.]
Lengauer, Thomas
Frishman, Dimitrij
Valencia, Alfonso
Viral Bioinformatics
In: Modern Genome Annotation - The BioSapiens Network, 429-452
Part of a BookF7F884E1485EA5ECC125758B002856FB-Lengauer2009x
2009[Alcaro, Stefano]
[Artese, Anna]
[Ceccherini-Silberstein, Francesca]
[Ortuso, Francesca]
[Perno, Carlo Federico]
Sing, Tobias
[Svicher, Valentina]
Molecular Dynamics and Free Energy Studies on the Wild-Type and Mutated HIV-1
Protease Complexed with Four Approved Drugs: Mechanism of Binding and
In: Journal of Chemical Information and Modeling [49], 1751-1761
Journal ArticleF143B7158EA481C7C12576F1004F849F-Becker2009
2009Altmann, André
[Däumer, Martin]
[Beerenwinkel, Niko]
[Peres, Yardena]
[Schülter, Eugen]
Büch, Joachim
[Rhee, Soo-Yon]
[Sönnerborg, Anders]
[Fessel, W. Jeffrey]
[Shafer, Robert W.]
[Zazzi, Maurizio]
[Kaiser, Rolf]
Lengauer, Thomas
Predicting the Response to Combination Antiretroviral Therapy: Retrospective Validation of
geno2pheno-THEO on a Large Clinical Database
In: The Journal of Infectious Diseases [199], 999-1006
Journal Article7437741FF0DD8974C125756000639546-Altmann2009JID
2009Altmann, André
Sing, Tobias
[Vermeiren, Hans]
[Winters, Bart]
[Van Craenenbroeck, Elke]
[Van der Borght, Koen]
[Rhee, Soo-Yon]
Shafer, Robert W.
[Schülter, Eugen]
[Kaiser, Rolf]
[Peres, Yardena]
[Sönnerborg, Anders]
Fessel, W. Jeffrey
[Incardona, Francesca]
[Zazzi, Maurizio]
[Bacheler, Lee]
[Van Vlijmen, Hermann]
Lengauer, Thomas
Advantages of Predicted Phenotypes and Statistical Learning Models in Inferring Virological Response to Antiretroviral Therapy from HIV Genotype
In: Antiviral Therapy [14], 273-283
Journal ArticleEC7EFA9EA38CD0D8C125756000644DA1-Altmann2009AVT
2009Blankenburg, Hagen
[Finn, Robert D.]
[Prlić, Andreas]
[Jenkinson, Andrew M.]
Ramírez, Fidel
Emig, Dorothea
Schelhorn, Sven-Eric
Büch, Joachim
Lengauer, Thomas
Albrecht, Mario
DASMI: exchanging, annotating and assessing molecular interaction data
In: Bioinformatics [25], 1321-1328
Journal ArticleB8DDEA6F0FE26990C12575EC0052FA94-Albrecht2009a
2009Bock, ChristophAttachment IconEpigenetic biomarker development
In: Epigenomics [1], 99-110
Journal ArticleF24963B3C52A6770C12576B70007A61A-Bock2009
2009Bock, Christoph
Halachev, Konstantin
Büch, Joachim
Lengauer, Thomas
Attachment IconEpiGRAPH: user-friendly software for statistical analysis and prediction of (epi)genomic data
In: Genome Biology [10], R14.1-R14.14
Journal Article02635734C5DA789AC1257574006AC7FF-Bock2009a
2009Ebert, PeterComputational Analysis of genomic HPV data
Universität des Saarlandes
Thesis - Bachelor thesis5C6C75FED321B845C1257834003C573B-Ebert2009a
2009Stop sign IconFeuerbach, Lars
Halachev, Konstantin
Lengauer, Thomas
Bock, Christoph
[Meijer, Gerrit]
[Ried, Thomas]
[Giaretti, Walter]
[Hamilton, Peter]
Stop sign IconAn exhaustive methode for CpG island annotation
In: Special Issue: Abstracts of the 3rd MC-GARD Meeting, 146-146
Poster1ED2DF87EA78FD77C12576B9003EE67E-Feuerbach2009_Poster1
2009[Frishman, Dmitrij]
Albrecht, Mario
Blankenburg, Hagen
[Bork, Peer]
[Harrington, Eoghan D.]
[Hermjakob, Henning]
[Jensen, Lars J.]
[Juan, David A.]
Lengauer, Thomas
[Pagel, Philipp]
[Schachter, Vincent]
[Valencia, Alfonso]
[Frishman, Dmitrij]
[Valencia, Alfonso]
Protein-protein interactions: analysis and prediction
In: Modern Genome Annotation - The Biosapiens Network, 353-410
Part of a BookDB34312C982D374AC125752B007D3C31-Albrecht2008k
2009Stop sign Icon[Harrigan, P Richard]
[McGovern, Rachel]
[Dong, Winnie]
Thielen, Alexander
[Jensen, Mark]
[Mo, Theresa]
[Chapman, Douglas]
[Lewis, Marilyn]
[James, Ian]
[Valdez, Hernan]
Stop sign IconScreening for HIV tropism using population-based V3 genotypic analysis: a retrospective outcome analysis using stored plasma screening samples from MOTIVATE-1
In: Abstracts presented at the XVIII International HIV Drug Resistance Workshop : Basic Principles & Clinical Implications, A17-A17
Poster64A182559A713DFEC12575D60045DC7B-Harrigan2009IDRW
2009Hartmann, Christoph
Antes, Iris
Lengauer, Thomas
Docking and scoring with alternative side-chain conformations
In: Proteins: Structure, Function, and Bioinformatics [74], 712-726
Journal ArticleBA30A24E54752F22C1257574005E599E-Hartmann2009
2009[Kono, Ken]
Bozek, Kasia
Domingues, Francisco S.
[Shioda, Tatsuo]
[Nakayama, Emi E.]
Impact of a single amino acid in the variable region 2 of the Old World monkey TRIM5alpha SPRY (B30.2) domain on anti-human immunodeficiency virus type 2 activity
In: Virology [388], 160-168
Journal Article4DD2923739BBD81BC12576930044E44D-Kono2009
2009Stop sign Icon[Lawyer, Glenn]
[Ferkingstad, Egil]
[Nesvåg, Rangan]
[Varnäs, Katarina]
[Agartz, Ingrid]
Stop sign IconLocal and covariate-modulated false discovery rates applied in neuroimaging
In: NeuroImage [47], 213-219
Journal ArticleE02E9BB3E478AB20C12576A90031ABAD-Lawyer2009_lFDR
2009Stop sign Icon[Lawyer, Glenn]
[Nesvåg, Ragnar]
[Varnäs, Katarina]
[Okugawa, Gaku]
[Agartz, Ingrid]
Stop sign IconGrey and white matter proportional relationships in the cerebellar vermis altered in schizophrenia
In: Cerebellum [8], 52-60
Journal Article4D0EA9962092DADDC12576A90031CB28-Lawyer2009_cerebellum
2009Lengauer, Thomas
Altmann, André
Thielen, Alexander
Bioinformatische Unterstützung der Auswahl von HIV Therapien
In: Informatik Spektrum [32], 320-331
Journal ArticleE829702BEC6B3F80C12576B2004CD281-LengAltThie2009
2009Lengauer, Thomas
[Kaiser, Rolf]
Computerjagd auf das AIDSVIRUS
In: Spektrum der Wissenschaft [08], 62-67
Journal Article5C35B88E006B6094C12576B1004C2D7F-LengauerKaiser2009a
2009Lengauer, Thomas
[Sierra, S.]
[Kaiser, Rolf]
Resistenzbestimmung
In: MMW Fortschritte in der Medizin [151], 74-75
Journal Article88EC9D11AE99FBB2C12576B2004D2B87-LengKaiSie2009
2009Mangels, MiriamIn Silico Models for the Prediction of Metabolism by Cytochrome P450 Enzymes
Universität des Saarlandes
Thesis - Bachelor thesis3D3EC42C0128B08AC1257577003066B7-Mangels2009
2009[Mihm, Ulrike]
[Ackermann, Oliver]
Welsch, Christoph
[Herrmann, Eva]
[Hofmann, Wolf Peter]
[Grigorian, Natalia]
[Welker, Martin Walter]
Lengauer, Thomas
[Zeuzem, Stefan]
[Sarrazin, Christoph]
Clinical relevance of the 2'-5'-oligoadenylate synthetase/RNase L system for treatment response in chronic hepatitis C
In: Journal of Hepatology [50], 49-58
Journal ArticleCECF1D8297B7B629C125757E004854C8-LengauerZeuzem2009
2009[Moser, Dirk]
[Ekawardhani, Savira]
[Kumsta, Robert]
[Palmason, Haukur]
Bock, Christoph
[Athanassiadou, Zoi]
[Lesch, Klaus-Peter]
[Meyer, Jobst]
Attachment IconFunctional Analysis of a Potassium-Chloride Co-Transporter 3 (SLC12A6) Promoter Polymorphism Leading to an Additional DNA Methylation Site
In: Neuropsychopharmacology [34], 458-467
Journal Article0BB2B1FF18801B6BC12575220079A4C8-Moser2009
2009[Prosperi, Mattia C. F.]
Altmann, André
[Rosen-Zvi, Michal]
[Aharoni, Ehud]
[Gabor, Borgulya]
[Fulop, Bazso]
[Sonnerborg, Anders]
[Schulter, Eugen]
[Struck, Daniel]
[Ulivi, Giovanni]
[Vandamme, Anne-Mieke]
[Vercauteren, Jurgen]
[Zazzi, Maurizio]
Investigation of expert rule bases, logistic regression, and non-linear machine learning techniques for predicting response to antiretroviral treatment
In: Antiviral Therapy [14], 433-442
Journal Article271301D850C81819C12576F10058EF9C-Altmann2009x
2009Roomp, Kirsten
[Rand, Jacquie]
Intensive blood glucose control is safe and effective in diabetic cats using home monitoring and treatment with glargine
In: Journal of feline medicine and surgery [11], 668-682
Journal Article21B5E1141E41E77BC12576F2002FDD73-Roomp2009
2009Schüffler, Peter
[Mikeska, Thomas]
[Waha, Andreas]
Lengauer, Thomas
Bock, Christoph
Attachment IconMethMarker: User-friendly design and optimization of gene-specific DNA methylation assays
In: Genome Biology [10], R105:1-R105:10
Journal Article311705DBDA6B650DC12576B7000806A7-Bock2009b
2009[Sichtig, Nadine]
[Sierra, Saleta]
[Kaiser, Rolf]
[Däumer, Martin]
[Reuter, Stefan]
[Schülter, Eugen]
Altmann, André
[Fätkenheuer, Gerd]
[Dittmer, Ulf]
[Pfister, Herbert]
[Esser, Stefan]
Evolution of raltegravir resistance during therapy
In: Journal of antimicrobial chemotherapy [64], 25-32
Journal Article7CE5E87BAD4FE1D1C12576F20035CAE8-Sichtig2009
2009[Sos, Martin L.]
[Michel, Kathrin]
[Zander, Thomas]
[Weiss, Jonathan]
[Frommolt, Peter]
[Pfeifer, Martin]
[Li, Danan]
[Ullrich, Roland]
[Koker, Mirjam]
[Fischer, Florian]
[Shimamura, Takeshi]
[Rauh, Daniel]
[Mermel, Craig]
[Fischer, Stefanie]
[Stückrath, Isabel]
[Heynck, Stefanie]
[Beroukhim, Rameen]
[Lin, William]
[Winckler, Wendy]
[Shah, Kinjal]
[LaFramboise, Thomas]
[Moriarty, Whei F.]
Hanna, megan
Tolosi, Laura
[Rahnenführer, Jörg]
[Verhaak, Roel]
[Chiang, Derek]
[Getz, Gad]
[Hellmich, Martin]
[Wolf, Jürgen]
[Girard, Luc]
[Peyton, Michael]
[Weir, Barbara A.]
[Chen, Tzu-Hsiu]
[Greulich, Heidi]
[Barretina, Jordi]
[Shapiro, Geoffrey I.]
[Garraway, Levi A.]
[Gazdar, Adi F.]
[Minna, John D.]
[Meyerson, Matthew]
[Wong, Kwok-Kin]
[Thomas, Roman K.]
Predicting drug susceptibility of non-small cell lung cancers based on genetic lesions
In: Journal of Clinical Investigation [119], 1727-1740
Journal Article1F98D2E30C8C5EACC12576F20037D14F-tolosi2009
2009[Susser, Simone]
Welsch, Christoph
[Wang, Yalan]
[Zettler, Markus]
Domingues, Francisco S.
[Karey, Ursula]
[Hughes, Eric]
[Ralston, Robert]
[Tong, Xiao]
[Herrmann, Eva]
[Zeuzem, Stefan]
[Sarrazin, Christoph]
Characterization of resistance to the protease inhibitor boceprevir in hepatitis C virus-infected patients.
In: Hepatology [50], 1709-1718
Journal Article5B7A2422265D4871C12576930046EDA1-Susser2009
2009Stop sign IconThielen, Alexander
Altmann, André
Bogojeska, Jasmina
[Kaiser, Rolf]
Lengauer, Thomas
Stop sign IconEstimating evolutionary pathways to 7CXCR4 usage from cross-sectional data
In: Abstracts presented at the XVIII International HIV Drug Resistance Workshop : Basic Principles & Clinical Implications, A16-A16
PosterAB26A70926E54FE5C12575D60045204D-Thielen2009IDRW
2009Stop sign IconThielen, Alexander
[Sichtig, Nadine]
[Braun, Patrick]
[Däumer, Martin]
[Walter, Hauke]
[Noah, Christian]
[Wolf, Eva]
[Müller, Harm]
[Stürmer, Martin]
Lengauer, Thomas
[Kaiser, Rolf]
[Obermeier, Martin]
Stop sign IconPerformance of genotypic coreceptor measurement using geno2pheno[coreceptor] in B- and non-B HIV subtypes in a large cohort of therapy-experienced patients in Germany
In: Reviews in Antiviral Therapy, 99-99
Poster2772CF0E7A49F03FC12575D600461462-Thielen2008EDRW
2009[Trignetti, Maria]
Sing, Tobias
[Svicher, Valentina]
[Santoro, Maria Mercedes]
[Forbici, Federica]
[D'Arrigo, Roberta]
[Bellocchi, Maria Concetta]
[Santoro, Mario]
[Marconi, Patrizia]
[Zaccarelli, Mauro]
[Trotta, Maria Paola]
[Bellagamba, Rita]
[Narciso, Pasquale]
[Antinori, Andrea]
Lengauer, Thomas
[Perno, Carlo Federico]
[Ceccherini-Silberstein, Francesca]
Dynamics of NRTI resistance mutations during therapy interruption
In: AIDS Research and Human Retroviruses [25], 57-64
Journal Article82264AE469BC0230C125757E00489F64-LengauerSing2009
2009Weimann, AaronUsing multidimensional Scaling for visualizing similarities of proteins
Universität des Saarlandes
Thesis - Bachelor thesisFC590D081D76D925C1257834003BC247-Weimann2009a
2008Stop sign IconAltmann, Andre
[Rosen-Zvi, Michal]
[Prosperi, Mattia]
[Aharoni, Ehud]
[Neuvirth, Hani]
[Schülter, Eugen]
Büch, Joachim
[Peres, Yardena]
[Incardona, Incardona]
[Sönnerborg, Anders]
[Kaiser, Rolf]
[Zazzi, Maurizio]
Lengauer, Thomas
Stop sign IconThe EuResist approach for predicting response to anti HIV-1 therapy
In: Reviews in Antiviral Therapy, 107
Poster37BB8F81589204E4C1257546004DB142-Altmann2008EDRW
2008Altmann, Andre
[Rosen-Zvi, Michal]
[Prosperi, Mattia]
[Aharoni, Ehud]
[Neuvirth, Hani]
[Sönnerborg, Anders]
[Schülter, Eugen]
Büch, Joachim
[Struck, Daniel]
[Peres, Yardena]
[Incardona, Francesca]
[Kaiser, Rolf]
[Zazzi, Maurizio]
Lengauer, Thomas
Comparison of Classifier Fusion Methods for Predicting Response to Anti HIV-1 Therapy
In: PLoS ONE [3], e3470
Journal Article4014325E58E801B4C125750D006D87CB-Altmann2008a
2008Assenov, Yassen
Ramírez, Fidel
Schelhorn, Sven-Eric
Lengauer, Thomas
Albrecht, Mario
Computing topological parameters of biological networks
In: Bioinformatics [24], 282-284
Journal Article670864261729C824C12573D00042B9FE-Albrecht2008b
2008Bickel, Steffen
Bogojeska, Jasmina
Lengauer, Thomas
Sheffer, Tobias
[McCallum, Andrew]
[Roweis, Sam]
Attachment IconMulti-Task Learning for HIV Therapy Screening
In: Proceedings, Twenty-Fifth International Conference on Machine Learning, 56-63
Proceedings ArticleECFE258759FA0F00C1257512004D71B6-Bickel_icml_2008
2008Bock, ChristophIVF: stars may have to consider the risk of stolen parenthood
In: Nature [454], 938
Journal ArticleD4D5075C9DF488A1C125752200792941-Bock2008d
2008Bock, Christoph
Lengauer, Thomas
Attachment IconComputational epigenetics
In: Bioinformatics [24], 1-10
Journal Article566DD9F499693093C12573B600592976-Bock2008a
2008Bock, Christoph
[Walter, Jörn]
[Paulsen, Martina]
Lengauer, Thomas
Attachment IconInter-individual variation of DNA methylation and its implications for large-scale epigenome mapping
In: Nucleic Acids Research [36], e55
Journal Article869594111BDC2511C125752200786FA4-Bock2008c
2008Bogojeska, Jasmina
Alexa, Adrian
Altmann, André
Lengauer, Thomas
[Rahnenführer, Jörg]
Attachment IconRtreemix: an R package for estimating evolutionary pathways and genetic progression scores
In: Bioinformatics [24], 2391-2392
Journal Article6B37EB33694127E1C125751200507021-Bogojeska_trees_2008
2008Bogojeska, Jasmina
Lengauer, Thomas
[Rahnenführer, Jörg]
Stability analysis of mixtures of mutagenetic trees
In: BMC Bioinformatics [9], 165-181
Journal Article6E2FC2E922E7046BC1257546004D255A-Bogojeska_bmc_2008
2008Stop sign IconDäumer, Martin
[Kaiser, Rolf]
[Klein, Rolf]
Lengauer, Thomas
[Thiele, Bernhard]
Thielen, Alexander
Stop sign IconInferring viral tropism from genotype with massively parallel sequencing; qualitative and quantitative analysis
In: Antiviral Therapy, A101
Poster7A5A4B81CE5E4662C1257546004D1B3C-Daumer2008
2008Emig, Dorothea
[Cline, Melissa S.]
[Klein, Karsten]
[Kunert, Anne]
[Mutzel, Petra]
Lengauer, Thomas
Albrecht, Mario
Integrative visual analysis of the effects of alternative splicing on protein domain interaction networks
In: Journal of Integrative Bioinformatics [5], 101-115
Journal ArticleE6694E00F56CAED8C125752B005F119D-Albrecht2008h
2008Emig, Dorothea
[Cline, Melissa S.]
Lengauer, Thomas
Albrecht, Mario
Integrating expression data with domain interaction networks
In: Bioinformatics [24], 2546-2548
Journal Article7CAE6B7AD3EA1068C125752B007C89F2-Albrecht2008j
2008Emig, Dorothea
[Klein, Karsten]
[Kunert, Anne]
[Mutzel, Petra]
Albrecht, Mario
Visualizing domain interaction networks and the impact of alternative splicing events
In: Proceedings of the 5th International Conference on BioMedical Visualization (MediVis): Information Visualization in Medical and Biomedical Informatics, 36-43
Proceedings Article060DE047371600D7C125752B005E9DE7-Albrecht2008g
2008[Franke, Andre]
[Balschun, Tobias]
[Karlsen, Tom H.]
[Sventoraityte, Jurgita]
[Nikolaus, Susanna]
Mayr, Gabriele
Domingues, Francisco S.
Albrecht, Mario
[Nothnagel, Michael]
[Ellinghaus, David]
[Sina, Christian]
[Onnie, Clive M.]
[Weersma, Rinse K.]
[Stokkers, Pieter C. F.]
[Wijmenga, Cisca]
[Gazouli, Maria]
[Strachan, David]
[McArdle, Wendy L.]
[Vermeire, Séverine]
[Rutgeers, Paul]
[Rosenstiel, Philip]
[Krawczak, Michael]
[Vatn, Morten H.]
[IBSEN study group, the]
[Mathew, Christopher G.]
[Schreiber, Stefan]
Sequence variants in IL10, ARPC2, and multiple other loci contribute to ulcerative colitis
In: Nature Genetics [40], 1319-1323
Journal ArticleAE4207758495F4CFC125752B0064899F-Albrecht2008i
2008[Hornstein, Max]
[Hoffmann, Michele J.]
Alexa, Adrian
[Yamanaka, Masanori]
[Müller, Mirko]
[Jung, Volker]
[Rahnenführer, Jörg]
[Schulz, Wolfgang A.]
Protein phosphatase and TRAIL receptor genes as new candidate tumor genes on chromosome 8p in prostate cancer
In: Cancer Genomics & Proteomics [5], 123-136
Journal Article445F5D1505484E6DC125755C0043F15D-HornsteinAlexa2008
2008[Jenkinson, Andrew M.]
Albrecht, Mario
[Birney, Ewan]
Blankenburg, Hagen
[Down, Thomas]
[Finn, Robert D.]
[Hermjakob, Henning]
[Hubbard, Tim J. P.]
[Jimenez, Rafael C.]
[Jones, Philip]
[Kähäri, Andreas]
[Kulesha, Eugene]
[Macías, José R.]
[Reeves, Gabrielle A.]
[Prlić, Andreas]
Integrating biological data - the Distributed Annotation System
In: BMC Bioinformatics [9], S3.1-7
Journal Article9AA8F9DAE2673611C125752B005DA191-Albrecht2008f
2008Kircher, Martin
Bock, Christoph
Paulsen, Martina
Attachment IconStructural conservation versus functional divergence of maternally expressed microRNAs in the Dlk1/Gtl2 imprinting region
In: BMC Genomics [9], 346
Journal ArticleCF6496BFA2CCEF63C1257574006C2B42-Kircher2008
2008[Lisurek, Michael]
[Simgen, Birgit]
Antes, Iris
[Bernhardt, Rita]
Theoretical and Experimental Evaluation of a CYP106A2 Low Homology Model and Production of Mutants with Changed Activity and Selectivity of Hydroxylation
In: ChemBioChem [9], 1439-1449
Journal ArticleB064E709880DB2DFC125757400605CAB-Antes2008b
2008[Lucas, Simon]
[Heim, Ralph]
[Negri, Matthias]
Antes, Iris
[Ries, Christina]
[Schewe, Katarzyna E.]
[Bisi, Alessandra]
[Gobbi, Silvia]
[Hartmann, Rolf W.]
Novel Aldosterone Synthase Inhibitors with Extended Carbocyclic Skeleton by a Combined Ligand-Based and Structure-Based Drug Design Approach
In: Journal of Medical Chemistry [51], 6138-6149
Journal Article78D9F65839D5084EC1257574005F9FD8-Antes2008a
2008Stop sign Icon[Moores, Andrew]
Thielen, Alexander
[Dong, Winnie]
Low, Andrew J.
[Woods, Conan]
[Jensen, Mark]
[Wynhoven, Brian]
[Chan, Dennison]
[Glascock, Christopher]
[Harrigan, P Richard]
Stop sign IconImproved detection of X4 virus by V3 genotyping: application to plasma RNA and proviral DNA
In: Antiviral Therapy, A99
Poster332CEC0F53742872C1257546004C2537-Moores2008
2008Müller, FabianInferring virological response to antiretroviral combination therapy based on past treatment lines
Universität des Saarlandes
Thesis - Bachelor thesis199C39DC7E056E83C1257560006E9CA1-FMueller2008_bachelor
2008Stop sign Icon[Obermeier, Martin]
[Berg, Thomas]
[Sichtig, Nadine]
[Braun, Patrick]
[Däumer, Martin]
[Walter, Hauke]
[Noah, Christian]
[Wolf, Eva]
[Müller, Harm]
[Stürmer, Martin]
Thielen, Alexander
[Kaiser, Rolf]
Stop sign IconDetermination of HIV-1 co-receptor usage in German patients – comparison of genotypic methods with the TROFILE® phenotypic assay
In: Abstracts of the Ninth International Congress on Drug Therapy in HIV Infection, 123
Poster56E99F0A8B46ACDFC1257546004BB273-Obermeier2008Glasgow
2008Stop sign Icon[Obermeier, Martin]
[Sichtig, Nadine]
[Braun, Patrick]
[Däumer, Martin]
[Walter, Hauke]
[Noah, Christian]
[Wolf, Eva]
[Müller, Harm]
[Stürmer, Martin]
[Kaiser, Rolf]
Thielen, Alexander
Stop sign IconDetermination of HIV-1 coreceptor usage in German patients - comparison of genotypic methods with the TROFILE phenotypic assay
In: Antiviral Therapy, A112
PosterB7E944E818C62C9BC1257546004C1D91-Obermeier2008
2008Perner, JulianeAttachment IconSemi-Supervised Learning for Predicting Anti-HIV Drug Resistance
Universität des Saarlandes
Thesis - Bachelor thesis1AADE81DE28F2C0DC1257560006AB91E-Perner2008_bachelor
2008[Rosen-Zvi, Michal]
Altmann, Andre
[Prosperi, Mattia]
[Aharoni, Ehud]
[Neuvirth, Hani]
[Sönnerborg, Anders]
[Schülter, Eugen]
[Struck, Daniel]
[Peres, Yardena]
[Incardona, Francesca]
[Kaiser, Rolf]
[Zazzi, Maurizio]
Lengauer, Thomas
Selecting anti-HIV therapies based on a variety of genomic and clinical factors
In: Proceedings of the 16th Annual International Conference on Intelligent Systems for Molecular Biology (ISMB 2008), i399-406
Proceedings Article2B507EB7E868B673C125750D006E9FD1-Rosen2008a
2008Stop sign Icon[Rosen-Zvi, Michal]
[Schülter, Eugen]
Altmann, Andre
[Sierra-Aragon, Saleta]
[Zazzi, Maurizio]
[Sönnerborg, Anders]
[Oette, Mark]
Lengauer, Thomas
[Kaiser, Rolf]
Stop sign IconSustaining lamivudine/emtricitabine, abacavir, zidovudine or atazanavir from a previous treatment shows a clinical benefit
In: Antiviral Therapy, A86
Poster5013764FF226D126C1257546004D668F-RosenZvi2008IDRW
2008Saigo, Hiroto
[Tsuda, Koji]
[Giannotti, Fosca]
[Gunopulos, Dimitrios]
Iterative Subgraph Mining for Principal Component Analysis.
In: Proceedings of the IEEE International Conference on Data Mining (ICDM2008), DM934
Proceedings ArticleBBDA67E6A3D20574C1257505005B12B0-Saigo2008a
2008Stop sign IconSander, Oliver
Altmann, Andre
Lengauer, Thomas
Stop sign IconComputational analysis of covariation and interactions between HIV-1 reverse transcriptase and Integrase
In: Reviews in Antiviral Therapy, 113-114
PosterF1EAE2F281181DFCC1257546004DE259-Sander2008EDRW
2008Sander, Oliver
Domingues, Francisco S.
Zhu, Hongbo
Lengauer, Thomas
Sommer, Ingolf
[Brazma, Alvis]
[Miyano, Satoru]
[Akutsu, Tatsuya]
Structural descriptors of protein-protein binding sites
In: Proceedings of 6th Asia-Pacific Bioinformatics Conference, 79-88
Proceedings ArticleD9FA9F827F5FBCBFC1257505004EAE44-Sander2008
2008Schelhorn, Sven-Eric
Lengauer, Thomas
Albrecht, Mario
An integrative approach for predicting interactions of protein regions
In: Bioinformatics [24], i35-i41
Journal ArticleB2A0CDBC092DA893C125752C0001A4CB-Albrecht2008l
2008Schlicker, Andreas
Albrecht, Mario
Attachment IconFunSimMat: a comprehensive functional similarity database
In: Nucleic Acids Research [36], D434-D439
Journal Article4EC5F9537DF4FB41C12573AE0054CD3A-Albrecht2008a
2008[Sierra, Saleta]
[Kaiser, Rolf]
Thielen, Alexander
[Sander, Oliver]
Lengauer, Thomas
[Jäger, Hans]Genotypic Analysis of HIV Co-Receptor Usage
In: Entry Inhibitoren - Neue Formen der HIV-Therapie, 31-39
Part of a BookD68D899D381A5EB8C12575390057C0FB-Jaeger2008
2008Stöckel, DanielProtein Surface Remeshing and Characterisation Using Morse-Smale Complexes
Universität des Saarlandes
Thesis - Bachelor thesis57F525EB6D8B6AB4C12575770030C1B0-Stöckel2008
2008Stop sign IconThielen, Alexander
[Harrigan, P Richard]
Low, Andrew J.
[Moores, A]
Altmann, Andre
Bozek, Kasia
[Heger, Eva]
[Sichtig, Nadine]
[Kaiser, Rolf]
Lengauer, Thomas
Stop sign IconImproved genotypic prediction of HIV-1 coreceptor usage by incorporating V2 loop sequence variation
In: Antiviral Therapy, A100
PosterBEAA728733F44A08C1257546004C2DEB-Thielen2008IDRW
2008Stop sign IconThielen, Alexander
[Kaiser, Rolf]
Lengauer, Thomas
Stop sign IconImproving HIV-1 coreceptor usage prediction from genotype with regions outside of V3
In: Reviews in Antiviral Therapy, 81-82
Poster4843DD090896EC33C1257546004CFEC0-Thielen2008Entry
2008[Van Ooijen, Gerben]
Mayr, Gabriele
Albrecht, Mario
[Cornelissen, Ben J. C.]
[Takken, Frank L. W.]
Transcomplementation, but not physical association of the CC-NB-ARC and LRR domains of tomato R protein Mi-1.2 is altered by mutations in the ARC2 subdomain
In: Molecular Plant [1], 401-410
Journal ArticleFC599FCE9BC04296C125752B005C7B6D-Albrecht2008e
2008[Van Ooijen, Gerben]
Mayr, Gabriele
[Kasiem, Mobien M. A.]
Albrecht, Mario
[Cornelissen, Ben J. C.]
[Takken, Frank L. W.]
Structure-function analysis of the NB-ARC domain of plant disease resistance proteins
In: Journal of Experimental Botany [59], 1383-1397
Journal Article0FBA1B919C6CF49CC125752B005BDD22-Albrecht2008d
2008Stop sign Icon[Verheyen, Jens]
Altmann, Andre
[Knops, Elena]
[Schülter, Eugen]
[Sichtig, Nadine]
[Reuter, Stefan]
[Fätkenheuer, Gerd]
[Pfister, Herbert]
[Kaiser, Rolf]
Stop sign IconRelevance of HIV gag cleavage site mutations in failures of protease inhibitor therapies
In: Antiviral Therapy, A53
PosterFE2CB8C044329BBBC1257546004E0BC3-Verheyen2008a
2008[Watson, James D.]
[Thornton, Janet M.]
[Tress, Michael L.]
[Lopez, Gonzalo]
[Valencia, Alfonso]
[Redfern, Oliver]
[Orengo, Christine A.]
Sommer, Ingolf
Domingues, Francisco S.
[Frishman, Dmitrij]
[Valencia, Alfonso]
Structure to function
In: Modern Genome Annotation, 239-262
Part of a Book843DE257F52B80DDC1257538005AA749-DominguesS2008
2008Weinhold, Nils
Sander, Oliver
Domingues, Francisco S.
Lengauer, Thomas
Sommer, Ingolf
Attachment IconLocal function conservation in sequence and structure space
In: PLoS Computational Biology [4], e1000105
Journal Article2DB9481E41B4192BC12575300071D22D-Weinhold2008
2008[Welsch, Christoph]
Domingues, Francisco S.
[Susser, Simone]
Antes, Iris
Hartmann, Christoph
Mayr, Gabriele
Schlicker, Andreas
[Sarrazin, Christoph]
Albrecht, Mario
[Zeuzem, Stefan]
Lengauer, Thomas
Attachment IconMolecular basis of telaprevir resistance due to V36 and T54 mutations in the NS3-4A protease of HCV
In: Genome Biology [9], R16
Journal Article8D6DA765556D9EC0C12573DD004C440B-Albrecht2008c
2008Zhu, Hongbo
Sommer, Ingolf
Lengauer, Thomas
Domingues, Francisco S.
Attachment IconAlignment of Non-Covalent Interactions at Protein-Protein Interfaces
In: PLoS ONE [3], e1926
Journal Article76B6F10503CD3F49C12575050048B89A-Zhu2008
2008Zotenko, Elena
Mestre, Julian
[O'Leary, Dianne]
[Przytycka, Teresa]
Why Do Hubs in the Yeast Protein Interaction Network Tend To Be Essential: Reexamining the Connection between the Network Topology and Essentiality
In: PLoS Computational Biology [4], e1000140
Journal Article677027344BF2FDD5C12575140058B930-Zotenko2008
2007[Ahlenstiel, G.]
Roomp, Kirsten
Däumer, Martin
[Nattermann, T.]
[Vogel, M.]
[Rockstroh, J.K.]
Beerenwinkel, Niko
Kaiser, R.
[Nischalke, H.-D.]
[Sauerbruch, T.]
Lengauer, Thomas
[Spengler, U.]
Attachment IconSelective pressures of HLA genotypes and antiviral therapy on human immunodeficiency virus type 1 sequence mutation at a population level
In: Clinical and Vaccine Immunology [14], 1266-1273
Journal ArticleF5B1B958FA534882C12573CC0037989E-Lengauer2007s
2007Altmann, Andre
[Beerenwinkel, Niko]
Sing, Tobias
Savenkov, Igor
[Däumer, Martin]
[Kaiser, Rolf]
[Rhee, Soo-Yon]
[Fessel, W Jeffrey]
[Shafer, Robert W]
Lengauer, Thomas
Improved prediction of response to antiretroviral combination therapy using the genetic barrier to drug resistance
In: Antiviral Therapy [12], 169-178
Journal Article6640B953DA2CDA2DC1257288005464A4-Altmann2007
2007Stop sign IconAltmann, Andre
[Däumer, Martin]
Sing, Tobias
[Beerenwinkel, Niko]
[Walter, Hauke]
[Kaiser, Rolf]
Lengauer, Thomas
Stop sign IconValidation of geno2pheno and THEO on a large independent clinical dataset
In: Proceedings of the 5th European HIV Drug Resistance Workshop, -
Poster229EDDA6EDABC51AC12572A4005AAEC8-Altmann2007b
2007Stop sign IconAltmann, Andre
Sing, Tobias
[Vermeiren, Hans]
[Winters, Bart]
[Van Craenenbroeck, Elke]
[Van der Borght, Koen]
[Rhee, Soo-Yon]
[Shafer, Robert W]
[Schülter, Eugen]
[Kaiser, Rolf]
[Peres, Yardena]
[Sonnerborg, Anders]
[Fessel, W Jeffrey]
[Incardona, Francesca]
[Zazzi, Maurizio]
[Bacheler, Lee]
[Van Vlijmen, Hermann]
Lengauer, Thomas
Stop sign IconInferring virological response from genotype: with or without predicted phenotypes?
In: Proceedings of the 16th International HIV Drug Resistance Workshop, S169
Poster06E374FBD11AB30AC125750F006362ED-Altmann2007IDRW
2007Blankenburg, HagenA Distributed Annotation System for Molecular Interactions
Ruprecht Karl Universität Heidelberg; Universität Heilbronn
Thesis - other5D01A18EF50F1EAFC12572C2003D2FFA-Blankenburg2007a
2007Bock, Christoph
Lengauer, Thomas
Attachment IconComputational Epigenetics: Bioinformatik für neue Wege in der Krebsforschung
In: Jahrbuch 2007, 271-277
Part of a Book4D533C96B4244D8FC12573B600598A8B-Bock2007c
2007Bock, Christoph
[Walter, Jörn]
[Paulsen, Martina]
Lengauer, Thomas
Attachment IconCpG Island Mapping by Epigenome Prediction
In: PLoS Computational Biology [3], 1055-1070
Journal ArticleA437CEAF7C1978E0C12573B60058087C-Bock2007a
2007[Ceccherini-Silberstein, Francesca]
[Svicher, Valentina]
Sing, Tobias
[Artese, Anna]
[Santoro, Maria Mercedes]
[Forbici, Federica]
[Bertoli, Ada]
[Alcaro, Stefano]
[Palamara, Guido]
[Monforte, Antonella d'Arminio]
[Balzarini, Jan]
[Antinori, Andrea]
Lengauer, Thomas
[Perno, Carlo Federico]
Attachment IconCharacterization and structural analysis of novel mutations in human immunodeficiency virus type 1 reverse transcriptase involved in the regulation of restistance to nonnucleoside inhibitors
In: Journal of Virology [81], 11507-11519
Journal Article142B4822A3CC878EC12573CC003737EA-Lengauer2007r
2007Domingues, Francisco S.
Lengauer, Thomas
Lengauer, ThomasInferring Protein Function from Protein Structure
In: Bioinformatics - From Genomes to Therapies 3. The Holy Grail: Molecular Function, 1211-1252
Part of a Book81BEEB27E2842CFAC12572A4005F749F-S.Domingues2006
2007Domingues, Francisco S.
[Rahnenführer, Jörg]
Lengauer, Thomas
Conformational analysis of alternative protein structures
In: Bioinformatics [23], 3131-3138
Journal ArticleD54541FD31C7CFFFC12573B7004EF1B3-Domingues2007b
2007Stop sign IconEmig, DorotheaStop sign IconThe Impact of Alternative Splicing on Protein Interaction Networks
Eberhard Karls Universität Tübingen
Thesis - other4C4F0825332514A8C12572C2003D09E3-Emig2007a
2007[Flockerzi, Aline]
Maydt, Jochen
[Frank, Oliver]
[Ruggieri, Alessia]
[Maldener, Esther]
[Seifarth, Wolfgang]
[Medstrand, Patrik]
Lengauer, Thomas
[Meyerhans, Andreas]
[Leib-Mosch, Christine]
[Meese, Eckart]
[Mayer, Jens]
Attachment IconExpression pattern analysis of transcribed HERV sequences is complicated by ex vitvo recombination
In: Retrovirology [4], 39
Journal ArticleED32C45DA204D1ABC12573CC00359BE8-Lengauer2007m
2007[Franke, Andre]
[Hampe, Jochen]
[Rosenstiel, Philip]
[Becker, Christoph]
[Wagner, Florian]
[Häsler, Robert]
[Little, Randall D.]
[Huse, Klaus]
[Ruether, Andreas]
[Balschun, Tobias]
[Wittig, Michael]
[ElSharawy, Abdou]
Mayr, Gabriele
Albrecht, Mario
[Prescott, Natalie J.]
[Onnie, Clive M.]
[Fournier, Hélène]
[Keith, Tim]
[Radelof, Uwe]
[Platzer, Matthias]
[Mathew, Christopher G.]
[Stoll, Monika]
[Krawczak, Michael]
[Nürnberg, Peter]
[Schreiber, Stefan]
Systematic association mapping identifies NELL1 as a novel IBD disease gene
In: PLoS ONE [2], e691.1-13
Journal ArticleEE184396B344ECB1C125733D0066E0B4-Albrecht2007h
2007[Hampe, Jochen]
[Franke, Andre]
[Rosenstiel, Philip]
[Till, Andreas]
[Teuber, Markus]
[Huse, Klaus]
Albrecht, Mario
Mayr, Gabriele
[De La Vega, Francisco M.]
[Briggs, Jason]
[Günther, Simone]
[Prescott, Natalie J.]
[Onnie, Clive M.]
[Häsler, Robert]
[Sipos, Bence]
[Fölsch, Ulrich R.]
Lengauer, Thomas
[Platzer, Matthias]
[Mathew, Christopher G.]
[Krawczak, Michael]
[Schreiber, Stefan]
A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1
In: Nature Genetics [39], 207-211
Journal ArticleD974ADE8F150F765C125725F00324C1A-Albrecht2007a
2007Hartmann, Christoph
Antes, Iris
Lengauer, Thomas
Attachment IconIRECS: A new algorithm for the selection of most probable ensembles of side-chain conformations in protein models.
In: Protein Science [16], 1294-1307
Journal Article8BD3BCE9CBA1676FC12573AE0055F3FC-Hartmann2007
2007[Hofmann, Wolf Peter]
[Fernandez, B.]
[Herrmann, E.]
Welsch, Christoph
[Mihm, Ulrike]
[Kronenberg, B.]
[Feldmann, G.]
[Spengler, U.]
[Zeuzem, Stefan]
[Sarrazin, Christoph]
Somatic hypermutation and mRNA expression levels of the BCL-6 gene in patients with hepatitis C virus-associated lymphoproliferative diseases
In: Journal of Viral Hepatitis [14], 484-491
Journal Article3357BDBE182186F3C12573EE004DB399-HofmannFernandez2007
2007[Hofmann, Wolf Peter]
Welsch, Christoph
[Takahashi, Yoshitomo]
[Miyajima, Hiroaki]
[Mihm, Ulrike]
[Krick, Christoph]
[Zeuzem, Stefan]
[Sarrazin, Christoph]
Identification and in silico characterization of a novel compound heterozygosty associated with hereditary aceruloplasminemia
In: Scandinavian Journal of Gastroenterology [42], 1088-1094
Journal ArticleF677193A3AAE8DAEC12573EE004A1E79-HofmannWelsch2007
2007Kämper, Andreas
[Rognan, Didier]
Lengauer, Thomas
Lengauer, ThomasLead Identification by Virtual Screening
In: Bioinformatics - From Genomes to Therapies 2. Getting at the Inner Workings: Molecular Interactions, 651-704
Part of a BookD10CCE81246C3C7BC12572A0007601D6-Kaemper2007a
2007[Ketter, Ralf]
[Kim, Yoo-Jin]
[Storck, Simone]
Rahnenführer, Jörg
[Romeike, Bernd F.M.]
[Steudel, Wolf-Ingo]
[Zang, Klaus D.]
[Henn, Wolfram]
Attachment IconHyperdiploidy defines a distinct cytogenetic entity of meningiomas
In: Journal of Neuro-Oncology [83], 213-221
Journal Article8BC307E4CA74179CC12572830032D2F0-Rahnenfuehrer2007d
2007[Ketter, Ralf]
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Beerenwinkel, Niko
Lengauer, Thomas
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[Zang, Klaus D.]
Rahnenführer, Jörg
Application of oncogenetic trees mixtures as a biostatistical model of the clonal cytogenetic evolution of meningiomas
In: International Journal of Cancer [121], 1473-1480
Journal Article6F05BC872276EA60C12573CC0035E75E-Lengauer2007n
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Sing, Tobias
Schüffler, Peter
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[Schneweis, Karl-Eduard]
[Eberl, Wolfgang]
[Oldenburg, Johannes]
[Brackmann, Hans H.]
[Rockstroh, Jürgen K.]
[Spengler, Ulrich]
Däumer, Martin
[Kaiser, Rolf]
Lengauer, Thomas
[Matz, Bertfried]
Fifteen years of env C2V3C3 evolution in six individuals clonally infected with human immunodeficiency virus type 1
In: Journal of Medical Virology [79], 1629-1639
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2007Lengauer, ThomasBioinformatics - From Genomes to Therapies 1. The Building Blocks: Molecular Sequences and StructuresBook29A4907E743B1520C1257282002FE4F4-LengauerBioInf1_2007
2007Lengauer, ThomasBioinformatics - From Genomes to Therapies 2. Getting at the Inner Workings: Molecular InteractionsBookA07CE1B99D30022BC1257295002A730C-LengauerBioInf2_2007
2007Lengauer, ThomasBioinformatics - From Genomes to Therapies 3. The Holy Grail: Molecular FunctionBook9F324F7233F7882BC1257295002AECE4-LengauerBioInf3_2007
2007Lengauer, ThomasBullinger, H.J.Bioinformatik
In: Technologiefüher - Grundlagen, Anwendungen, Trends, 4
Part of a Book2CC2BC612BC0A326C125758B00266F9F-Lengauer2007m2
2007Lengauer, ThomasLengauer, ThomasFuture Trends
In: Bioinformatics - From Genomes to Therapies 3. The Holy Grail: Molecular Function, 1651-1687
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2007Lengauer, ThomasLengauer, ThomasIntroduction
In: Bioinformatics - From Genomes to Therapies 1. The Building Blocks: Molecular Sequences and Structures, 1-24
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2007Lengauer, ThomasReuse, Bernd
Vollmar, Roland
Strategiekonzept "Molekulare Bioinformatik"
In: Informatikforschung in Deutschland, 9
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Sander, Oliver
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Thielen, Alexander
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Bioinformatics prediction of HIV coreceptor usage
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Attachment IconThe human genomic melting map
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Journal Article27A694853F3231F9C12573B60058ACFF-Liu2007
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Current V3 genotyping algorithms are inadequate for predicting X4 co-receptor usage in clinical isolates
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Domingues, Francisco S.
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Attachment IconComparative Analysis of Protein Structure Alignments
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Bock, Christoph
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Attachment IconOptimization of Quantitative MGMT Promoter Methylation Analysis Using Pyrosequencing and Combined Bisulfite Restriction Analysis
In: Journal of Molecular Diagnostics [9], 368-381
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2007Rahnenführer, Jörg
Lengauer, Thomas
Lengauer, ThomasAnalysis of Expression Data: Classification of genes
In: Bioinformatics - From Genomes to Therapies 2. Getting at the Inner Workings: Molecular Interactions, 993-1021
Part of a Book3535883977EED76CC12572350041DE29-Rahnenfuehrer2007a
2007Ramírez, Fidel
Schlicker, Andreas
Assenov, Yassen
Lengauer, Thomas
Albrecht, Mario
Computational analysis of human protein interaction networks
In: Proteomics [7], 2541-2552
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2007Roomp, KirstenLengauer, ThomasEvolution of Drug Resistance in HIV
In: Bioinformatics - From Genomes to Therapies 3. The Holy Grail: Molecular Function, 1457-1496
Part of a Book8C113E0BE09FE69EC12572A00076C8EA-Roomp2007d
2007[Salamat-Miller, Nazila]
[Fang, Jianwen]
[Seidel, Christopher W.]
Assenov, Yassen
Albrecht, Mario
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Attachment IconA network-based analysis of polyanion-binding proteins utilizing human protein arrays
In: Journal of Biological Chemistry [282], 10153-10163
Journal Article60CAD5331BBAFC99C125728300811585-Albrecht2007b
2007Sander, Oliver
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Lengauer, Thomas
Domingues, Francisco S.
Attachment IconStructural Descriptors of gp120 V3 Loop for the Prediction of HIV-1 Coreceptor Usage
In: PLoS Computational Biology [3], 555-564
Journal Article9809883503D11D5DC12572A500529A60-Sander2007
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Albrecht, Mario
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Lengauer, Thomas
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Identification of PatL1, a human homolog to yeast P body component Pat1
In: Biochimica et Biophysica Acta - Molecular Cell Research [1773], 1786-1792
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2007Schlicker, Andreas
Huthmacher, Carola
Ramírez, Fidel
Lengauer, Thomas
Albrecht, Mario
Attachment IconFunctional evaluation of domain-domain interactions and human protein interaction networks
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Lengauer, Thomas
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Attachment IconFactor interaction analysis for chromosome 8 and DNA methylation alterations highlights innate immune response suppression and cytoskeletal changes in prostate cancer
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Thielen, Alexander
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Attachment IconGenotypic coreceptor analysis.
In: European Journal of Medical Research [12], 453-462
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Attachment IconMutagenetic tree Fisher kernel improves prediction of HIV drug resistance from viral genotype
In: Advances in Neural Information Processing Systems 19, 1-9
Proceedings Article845535906AEB88E6C12572880055BEE4-SingNIPS2006
2007Sing, Tobias
Low, Andrew J.
Beerenwinkel, Niko
Sander, Oliver
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Domingues, Francisco S.
Büch, Joachim
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Lengauer, Thomas
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Predicting HIV coreceptor usage on the basis of genetic and clinical covariates
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Sing, Tobias
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Attachment IconVariants in a novel epidermal collagen gene (COL29A1) are associated with atopic dermatitis
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2007Sommer, IngolfLengauer, ThomasProtein Fold Recognition Based on Distant Homologs
In: Bioinformatics - From Genomes to Therapies 1. The Building Blocks: Molecular Sequences and Structures, 351-388
Part of a BookDD2B0D60C8252EC0C12572840039A3F3-Sommer2007
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Müller, Oliver
Domingues, Francisco S.
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Lengauer, Thomas
Moment invariants as shape recognition technique for comparing protein binding sites
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Lengauer, Thomas
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Combined similarity and QSPR virtual screening for guest molecules of $\beta$-cyclodextrin
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Improved cyclodextrin-based receptors for camptothecin by inverse virtual screening
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Correlation nonstructural (NS)4B amino acid variations with initial viral kinetics during interferon-alpha-based therapy in HCV-1b-infected patients
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Structural and functional comparison of the non-structural protein 4B of flaviviridae
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Update on the domain architectures of NLRs and R proteins
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2006Alexa, Adrian
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Attachment IconImproved Scoring of Functional Groups from Gene Expression Data by Decorrelating GO Graph Structure
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2006Stop sign IconAntes, Iris
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Lengauer, Thomas
Attachment IconDynaPred: A structure and sequence based method for the prediction of MHC class I binding peptide sequence and conformations
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2006Bock, ChristophBioinformatik: Neue Strategien gegen Krebs
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Bioinformatisches Data Mining erschließt neue Strategien gegen Krebs
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Attachment IconAnalysis and Prediction of Helix Shift Errors in Homology Modeling
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An arginine/lysine-rich motif is crucial for VCP/p97-mediated modulation of ataxin-3 fibrillogenesis
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2006Stop sign IconFrings, OliverStop sign IconDevelopment of a
Smith-Waterman-Like Multi-Aspect
Alignment Tool
Universität des Saarlandes
Thesis - Bachelor thesis855991181C76D134C12572960032BB68-Frings2006a
2006Stop sign IconGlaab, EnricoStop sign IconOn the predictability of CpG methylation in human tissue at single basepair resolution
Universität des Saarlandes
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Computational recognition of potassium channel sequences
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2006Stop sign IconHobler, AnnaStop sign IconDocking of monosaccharids into the wild type and mutants of pyranose 2-oxidase
Universität des Saarlandes
Thesis - Bachelor thesis35FEA36A1FEEF674C12572AA0049ED23-Hobler2006
2006Huthmacher, CarolaDecomposing Protein Networks Into
Domain-Domain Interactions
Eberhard Karls University Tübingen
Thesis - other4459D5336D4C3480C12572960033D7A7-Huthmacher2006a
2006Stop sign IconJung, HolgerStop sign IconYamada Analyzer - A tool for fast calculation of genomic attributes
Universität des Saarlandes
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2006Kämper, Andreas
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Lengauer, Thomas
Fully Automated Flexible Docking of Ligands into Flexible Synthetic Receptors Using Forward and Inverse Docking Strategies
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Sing, Tobias
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Lengauer, Thomas
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Stable coreceptor usage of HIV in patients with ongoing treatment failure on HAART
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2006Lengauer, Thomas
Domingues, F.S.
Sommer, Ingolf
Zhu, Hongbo
Analysis and prediction of protein-protein-interaction types
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2006Lengauer, Thomas
Sing, Tobias
Bioinformatics-assisted anti-HIV therapy
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2006Maydt, Jochen
Lengauer, Thomas
Recco: recombination analysis using cost optimization
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Albrecht, Mario
Lengauer, Thomas
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Amino acid variations in hepatitis C virus p7 and sensitivity to antiviral combination therapy with amantadine in chronic hepatitis C
In: Antiviral Therapy [11], 507-519
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2006[Neumann, Dirk]
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Lengauer, Thomas
A Fully Computational Model for Predicting Percutaneous Drug Absorption
In: Journal of Chemical Information and Modeling [1], 424-429
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2006Stop sign Icon[Neumann, Dirk]
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Lengauer, Thomas
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2006Stop sign IconPfeifer, SusanneStop sign IconDevelopment of a fast
geometry-based screening
compound prefiltering technique
Universität des Saarlandes
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2006[Plotz, Guido]
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Albrecht, Mario
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Biondi, Ricardo M.
Lengauer, Thomas
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Attachment IconMutations in the MutSalpha interaction interface of MLH1 can abolish DNA mismatch repair
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2006Stop sign IconReimer, DanielaStop sign IconDocking studies to investigate the effect of correlated mutations in the HIV-Protease on the drug resistance of HIV
Universität des Saarlandes
Thesis - Bachelor thesis561CB0E0DFF75613C12572AA00495197-Reimer2006
2006Roomp, Kirsten
Beerenwinkel, Niko
Sing, Tobias
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Büch, Joachim
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Lengauer, Thomas
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Arevir: A Secure Platform for Designing Personalized Antiretroviral Therapies Against HIV
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Albrecht, Mario
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A network-based analysis of polyanion-binding proteins utilizing yeast protein arrays
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Huthmacher, Carola
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Lengauer, Thomas
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Functional evaluation of domain-domain interactions and human protein interaction networks
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Sander, Oliver
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Lengauer, Thomas
ROCR: Visualizing classifier performance in R
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2006Steffen, Andreas
Kämper, Andreas
Lengauer, Thomas
Flexible Docking of Ligands into Synthetic Receptors Using a Two-Sided Incremental Construction Algorithm
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[Turner, Anthony P. F.]Virtual screening for guest molecules of a biosensor
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Lengauer, Thomas
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Involvement of novel HIV-1 reverse transcriptase mutations in the regulation of resistance to nucleoside inhibitors
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Resistance proteins: molecular switches of plant defence
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Development of Computational Methods for Analysis of Metabolic Profiling Data
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Mutations in the NB-ARC domain of I-2 that impair ATP hydrolysis cause autoactivation
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Metabolic high- content screening of Saccharomyces cerevisiae reveals superior performance of single gene deletion strains
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Compensatory mutations at the HIV cleavage sites p7/p1 and p1/p6-gag in therapy-naive and therapy-experienced patients
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[Hartmann, Rolf W.]
Synthesis and evaluation of heteroaryl substituted dihydronaphthalenes and indenes: potent and selective inhibitors of aldosterone synthase (CYP11B2) for the treatment of congestive heart failure and myocardial fibrosis
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Rahnenführer, Jörg
Lengauer, Thomas
Attachment IconModel Selection for Mixtures of Mutagenetic Trees
In: Statistical Applications in Genetics and Molecular Biology [5], Article 17
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2006Stop sign IconZimmer, TobiasStop sign IconFunctional Site Scaffolds
Universität des Saarlandes
Thesis - Bachelor thesis3E9F8182F867646FC12572960033A223-Zimmer2006a
2005Albrecht, MarioLRRK2 mutations and parkinsonism
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Lengauer, Thomas
The HIN domain of IFI-200 proteins consists of two OB folds
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2005Albrecht, Mario
Huthmacher, Carola
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Lengauer, Thomas
Decomposing protein networks into domain-domain interactions
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2005Antes, Iris
Merkwirth, Christian
Lengauer, Thomas
POEM: Parameter Optimization using Ensemble Methods: Application to target specific scoring functions
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2005[Balduin, Melanie]
Beerenwinkel, Niko
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[Däumer, Martin]
[Rockstroh, Jürgen]
[Oette, Mark]
[Fätkenheuer, Gerd]
[Kupfer, Bernd]
[Hoffmann, Daniel]
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[Kaiser, Rolf]
Evolution of HIV resistance during treatment interruption in experienced patients and after restarting a new therapy
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2005Beerenwinkel, Niko
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Sing, Tobias
Rahnenführer, Jörg
Lengauer, Thomas
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[Hoffmann, Daniel]
[Kaiser, Rolf]
Estimating HIV evolutionary pathways and the genetic barrier to drug resistance
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2005Beerenwinkel, Niko
Rahnenführer, Jörg
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[Selbig, Joachim]
Lengauer, Thomas
Learning multiple evolutionary pathways from cross-sectional data
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2005Beerenwinkel, Niko
Rahnenführer, Jörg
[Kaiser, Rolf]
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[Selbig, Joachim]
Lengauer, Thomas
Mtreemix: a software package for learning and using mixture models of mutagenetic trees
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Journal Article4C564AAE738324A8C1256F8D006254C9-Beerenwinkel2005b
2005[Beerenwinkel, Niko]
Sing, Tobias
Lengauer, Thomas
Rahnenführer, Jörg
Roomp, Kirsten
Savenkov, Igor
[Fischer, Roman]
[Hoffmann, Daniel]
[Selbig, Joachim]
[Korn, Klaus]
[Walter, Hauke]
[Berg, Thomas]
[Braun, Patrick]
[Fätkenheuer, Gerd]
[Oette, Mark]
[Rockstroh, Jürgen]
[Kupfer, Bernd]
[Kaiser, Rolf]
[Däumer, Martin]
Computational methods for the design of effective therapies against drug resistant HIV strains
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2005Bock, Christoph
Lengauer, Thomas
[Reither, Sabine]
[Mikeska, Thomas]
[Paulsen, Martina]
[Walter, Jörn]
Attachment IconBiQ Analyzer: visualization and quality control for DNA methylation data from bisulfite sequencing
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Albrecht, Mario
Lengauer, Thomas
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Structural and functional analysis of a novel mutation of CYP21B in a heterozygote carrier of 21-hydroxylase deficiency
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Albrecht, Mario
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Lengauer, Thomas
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Diversity and functional plasticity of eukaryotic selenoproteins: Identification and characterization of the SelJ family
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Hahn, Andreas
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Albrecht, Mario
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[Lucius, Ralph]
[Klöppel, Günther]
[Eickhoff, Holger]
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Lengauer, Thomas
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Dissection of the inflammatory bowel disease transcriptome using genome-wide cDNA microarrays identifies novel candidate disease genes
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Retinal properties and potential of the adult mammalian ciliary epithelium stem cells
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2005Djoumbou, YannickDocking studies to investigate the effect of correlated mutations in the HIV-Protease on the drug resistance of HIV
Universität des Saarlandes
Thesis - Bachelor thesis7941057214A88A7DC12572AA00491C85-djoumbou2005
2005[Gu, Wei]
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Antes, Iris
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Alternative Binding Modes of Polyproline Peptides Binding to the GYF Domain
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2005Hahn, Andreas
Rahnenführer, Jörg
Talwar, Priti
Lengauer, Thomas
Confirmation of human protein interaction data by human expression data
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Lengauer, Thomas
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Multiple-Ligand-Based Virtual Screening: Methods and Applications of the MTree Approach
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Journal ArticleB54DE070A54B282BC12570F9003F51A4-Lengauer2005b
2005Immesberger, StefanAttachment IconA Prefiltering Method to Speed up Protein
Structure Prediction
Universität des Saarlandes
Thesis - Bachelor thesisF3769AE00D70958DC12572960032EF28-Immesberger2005a
2005[Kaiser, Rolf]
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[Lehmann, C.]
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Sing, Tobias
[Schmeisser, N.]
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Fätkenheuer, Gerd
Stable coreceptor usage of HIV-1 in patients with ongoing treatment failure on HAART
In: Proceedings of the 3rd European HIV Drug Resistance Workshop, -
Proceedings ArticleA1569908BDACCE5CC1256FB7007FFFDB-Kaiser2005
2005Kämper, Andreas
Kaspar, Melanie
Lengauer, Thomas
Efficient conformational analysis of synthetic receptors with macrocyclic and fused ring systems
In: Synthetic Receptors 2005: Second World Congress on Synthetic Receptors, O4
Proceedings Article1FA79F16B19AD9C6C12570B3005A9A10-Kaemper2005
2005Kaspar, MelanieAttachment IconConformational Analysis of Macrocyclic Ring Systems
Universität des Saarlandes
Thesis - Bachelor thesisE502B1198E747DF7C125729600328D34-Kaspar2005a
2005Krier, MarkusAttachment IconMotif Search in Protein Sequences for Protein
Structure Prediction
Universität des Saarlandes
Thesis - Bachelor thesis911B87F9AC78D72EC125729600327195-Krier2005a
2005Lengauer, Thomas
Albrecht, Mario
[Sarrazin, C.]
[Mihm, U.]
[Herrmann, E.]
Welsch, Christoph
[Sarrazin, U.]
[Traver, S.]
[Zeuzem, S.]
Replication enhancing mutations of the Hepatitis C virus replicon: Prevalence and clinical significance in patients with chronic Hepatitis C
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2005Lengauer, Thomas
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Automatic Generation of complementary descriptors with molecular graph networks
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Journal ArticleAF06D0952F0CB1A2C12570F9003E98E4-lengauer2005a
2005Lengauer, Thomas[Meyers, Robert A.]Attachment IconInformatics (Computational Biology)
In: Growth Factors and Oncogenes in Gastrointestinal Cancers to Informatics (Computational Biology), 567-626
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2005Meiser, InaIdentification of functionally important regions in cytochrome P450 systems and a systematic analysis of various CYP P450 homology models
Universität des Saarlandes
Thesis - Bachelor thesisDED2654AED959AA0C12572AA004900EF-Meiser2005
2005Nickels, StefanAttachment IconGenerating Molecular Hashcodes for
Finding Duplicates in Virtual Screening
Libraries
Universität des Saarlandes
Thesis - Bachelor thesis7487D4AB5340F917C12572960033195A-Nickels2005a
2005Rahnenführer, JörgClustering algorithms and other exploratory methods for microarray data analysis
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2005Rahnenführer, JörgImage analysis for cDNA microarrays
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2005Rahnenführer, Jörg
Beerenwinkel, Niko
[Schulz, Wolfgang A.]
[Hartmann, Christian]
[von Deimling, Andreas]
[Wullich, Bernd]
Lengauer, Thomas
Estimating cancer survival and clinical outcome based on genetic tumor progression scores
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Journal Article6C73FBA76D1D18F3C1256FA4003676D6-Rahnenfuehrer2005a
2005[Ralser, Markus]
Albrecht, Mario
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Lengauer, Thomas
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[Krobitsch, Sylvia]
An integrative approach to gain insights into the cellular function of human ataxin-2
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2005[Ralser, Markus]
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Albrecht, Mario
Lengauer, Thomas
[Wanker, Erich E.]
[Lehrach, Hans]
[Krobitsch, Sylvia]
Ataxin-2 and huntingtin interact with endophilin-A complexes to function in plastin-associated pathways
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2005[Sarrazin, Christoph]
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[Herrmann, Eva]
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Albrecht, Mario
[Sarrazin, Ulrike]
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Lengauer, Thomas
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Clinical significance of in vitro replication-enhancing mutations of the hepatitis C virus (HCV) replicon in patients with chronic HCV infection
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Journal ArticleA44E9ADCDE1B3B61C125701100398786-Albrecht2005g
2005[Schreiber, Stefan]
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Albrecht, Mario
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Genetics of Crohn disease, an archetypal inflammatory barrier disease
In: Nature Reviews Genetics [6], 376-388
Journal ArticleBDED0D6DD6E26F80C1256FBA006DD712-Albrecht2005f
2005Stop sign IconSing, Tobias
Beerenwinkel, Niko
[Kaiser, Rolf]
[Hoffmann, Daniel]
[Däumer, Martin]
Lengauer, Thomas
Stop sign IconGeno2pheno[coreceptor]: a tool for predicting coreceptor usage from genotype and for monitoring coreceptor-associated sequence alterations
In: Proceedings of the 3rd European HIV Drug Resistance Workshop, -
Poster1F9471F63CB4BAB2C1256FB700532B1E-Sing2005b
2005Sing, Tobias
[Svicher, Valentina]
Beerenwinkel, Niko
[Ceccherini-Silberstein, Francesca]
[Däumer, Martin]
[Kaiser, Rolf]
[Walter, Hauke]
[Korn, Klaus]
[Hoffmann, Daniel]
[Oette, Mark]
[Rockstroh, Jürgen K.]
Fätkenheuer, Gerd
[Perno, Carlo-Federico]
Lengauer, Thomas
[Jorge, A]
[Torgo, L]
[Brazdil, P]
[Camacho, R]
[Gama, J]
Characterization of novel HIV Drug Resistance Mutations using clustering, multidimensional scaling and SVM-based feature ranking
In: Knowledge Discovery in Databases: PKDD 2005., 285-296
Proceedings Article33FB8006EA995E2FC125728800409E21-Sing2005pkdd
2005Steffen, Andreas
Kämper, Andreas
Lengauer, Thomas
Turner, A.P.F.FlexR - A new tool for predicting the structure of synthetic host-guest complexes
In: Synthetic Receptors 2005: Second World Congress on Synthetic Receptors, O7
Proceedings Article98B908B2234102CEC12570B3005B346E-Steffen2005
2005[Svicher, Valentina]
[Ceccherini-Silberstein, Francesca]
Sing, Tobias
[Santoro, Maria Mercedes]
[Gori, C.]
Beerenwinkel, Niko
[Gago, F.]
[D'Arrigo, R.]
[Bellocchi, M. C.]
[Giannella, S.]
[Bertoli, A.]
[D'Arminio Monforte, A.]
[Antinori, A.]
[Perno, Carlo-Federico]
Additional Mutations in HIV-1 Reverse Transcriptase are Involved in the Highly Ordered Regulation of NRTI Resistance
In: Proceedings of the 3rd European HIV Drug Resistance Workshop, -
Proceedings Article0FD71277D572E56BC1256FB700556414-Svicher2005b
2005Stop sign Icon[Svicher, Valentina]
[Ceccherini-Silberstein, Francesca]
Sing, Tobias
[Santoro, Maria Mercedes]
[Gori, C.]
Beerenwinkel, Niko
[Gago, F.]
[D'Arrigo, R.]
[Bellochi, M.C.]
[Giannella, S.]
[Bertoli, A.]
[D'Arminio Monforte, A.]
[Antinori, A.]
[Perno, Carlo-Federico]
Stop sign IconA highly ordered network of HIV-1 RT mutations regulates the continuous escape from antiviral drugs
In: International Workshop in HIV Dynamics and Evolution, -
Proceedings ArticleD27918C5AC5D6BBFC1256FB70055CBA4-Svicher2005a
2005Stop sign IconTalwar, Priti
Lengauer, Thomas
Rahnenführer, Jörg
[Heinzle, Elmar]
[Velagapudi, VR]
[Wittmann, Christoph]
Stop sign IconTowards computational analysis of metabolic profiling data for protein function prediction.
In: Proceedings of the Yeast Systems Biology, 6th International Conference on Systems Biology (ICSB 2005), 1
Poster3365F4847CF4C750C12572960036002A-Talwar2006a
2005Stop sign IconTalwar, Priti
Lengauer, Thomas
Rahnenführer, Jörg
[Wittmann, Christoph]
[Velagapudi, VR]
[Heinzle, Elmar]
Stop sign IconComputational Methods for Protein Function Prediction using Metabolomics Data
In: Proceedings of International Workshop on Systems Biology 2005, 1
Poster846986632A17E41CC12572960036F614-Talwar2005
2005[Ulmschneider, Sarah]
[Mueller-Vieira, Ursula]
[Klein, Christian D.]
Antes, Iris
Lengauer, Thomas
[Hartmann, Rolf W.]
Synthesis and Evaluation of Pyridylmethylene-tetrahydronaphthalenes and -indanes: Potent and Selective Inhibitors of Aldosterone Synthase (CYP11B2)
In: Journal of Medicinal Chemistry [48], 4489-4490
Journal ArticleF5933B18291C196EC1256FBC007D318F-Antes2005a
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[Hartmann, Rolf W.]
[Oberwinkler-Marchais, S]
[Klein, Christian D.]
[Bureik, M.]
[Bernhardt, R.]
Antes, Iris
Lengauer, Thomas
Synthesis and Evaluation of Imidazolylmethylenetetrahydronaphthalenes and Imidazolylmethyleneindanes: Potent Inhibitors of Aldosterone Synthase
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Journal ArticleA1FA14209B08212CC1256FBC007DCA97-Antes2005b
2005[Valentonyte, Ruta]
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[Huse, Klaus]
[Rosenstiel, Philip]
Albrecht, Mario
[Stenzel, Annette]
[Nagy, Marion]
[Gaede, Karoline I.]
[Franke, Andre]
[Haesler, Robert]
[Koch, Andreas]
Lengauer, Thomas
[Seegert, Dirk]
[Reiling, Norbert]
[Ehlers, Stefan]
[Schwinger, Eberhard]
[Platzer, Mathias]
[Krawczak, Michael]
[Müller-Quernheim, Joachim]
[Schürmann, Manfred]
[Schreiber, Stefan]
Sarcoidosis is associated with a truncating splice site mutation in BTNL2
In: Nature Genetics [37], 357-364
Journal ArticleC5973DDE5A22DC7DC1256FB6005C8085-Albrecht2005c
2005[Van Duist, Marjan M.]
Albrecht, Mario
[Podswiadek, Marta]
[Giachino, Daniela]
Lengauer, Thomas
[Punzi, Leonardo]
[De Marchi, Mario]
A new CARD15 mutation in Blau syndrome
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Journal Article26ED07859EF2BE81C1256FB6005D7BC6-Albrecht2005e
2005[Voets, Marieke]
Antes, Iris
[Scherer, C]
[Mueller-Vieira, U.]
[Biemel, K.]
[Barrassin, C.]
[Marchais-Oberwinkler, S.]
[Hartmann, R. W.]
Heteroaryl-substituted naphthalenes and structurally modified derivatives: selective inhibitors of CYP11B2 for the treatment of congestive heart failure and myocardial fibrosis
In: Journal of Medicinal Chemistry [48], 6632-6642
Journal ArticleCF4A51BEEE0B0D06C12570DF0046D58F-Antes2005e
2005Volkamer, AndreaAttachment IconImplementation of a method to filter
out compounds with toxic, reactive
and unsuitable functional groups
Universität des Saarlandes
Thesis - Bachelor thesis9A19409957FC92E6C12572960031795C-Volkamer2006a
2005Weiss, JuliaAttachment IconGenerating Frequency Profiles from Multiple
Structure Alignments
Universität des Saarlandes
Thesis - Bachelor thesis81D941F37658B741C1257296003250B9-Weiss2005a
2005[Wemmert, Silke]
[Ketter, Ralf]
Rahnenführer, Jörg
Beerenwinkel, Niko
[Strowitzki, Martin]
[Feiden, Wolfgang]
[Hartmann, Christian]
Lengauer, Thomas
[Stockhammer, Florian]
[Zang, Klaus D.]
[Meese, Eckart]
[Steudel, Wolf-Ingo]
[von Deimling, Andreas]
[Urbschat, Steffi]
Attachment IconPatients with high grade gliomas harboring delections of chromosomes 9p and 10q benefit from temozolomide treatment
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Journal Article82C9849633E76B4BC1257050003932DA-Wemmert05
2005Yalak, GarifAttachment IconAnalysis of Mutations in the Death Domains, Death Effector Domains, Caspase
Recruitment Domains, and Pyrin Domains
Universität des Saarlandes
Thesis - Bachelor thesis71C65F14BBADA555C1257296003222A1-Yalak2004a
2005Stop sign IconZhu, Hongbo
Domingues, Francisco S.
Sommer, Ingolf
Lengauer, Thomas
Stop sign IconAnalysis and prediction of protein-protein interaction types
In: 4th European Conference on Computational Biology (ECCB05), 1
Poster8D5B57B75B49CF5BC125723500451F0E-Zhu2005
2004Albrecht, Mario
[Golatta, Michael]
[Wüllner, Ullrich]
Lengauer, Thomas
Structural and functional analysis of ataxin-2 and ataxin-3
In: European Journal of Biochemistry [271], 3155-3170
Journal ArticleA051ECD11CF2842CC1256E7F005E1F28-Albrecht2004d
2004Albrecht, Mario
Lengauer, Thomas
Novel Sm-like proteins with long C-terminal tails and associated methyltransferases
In: FEBS Letters [569], 18-26
Journal Article9B65820089A086C1C1256E7F005DF132-Albrecht2004c
2004Albrecht, Mario
Lengauer, Thomas
Survey on the PABC recognition motif PAM2
In: Biochemical and Biophysical Research Communications [316], 129-138
Journal Article6EE815DA6CCE03B4C1256E44005DC3CE-Albrecht2004a
2004Beerenwinkel, NikoComputational Analysis of HIV Drug resistance DataBookB4B94ECDDF63DBC4C1256F8F006C38D7-Beerenwinkel2004
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Das Arevir-Projekt : neue Wege zur Optimierung von Anti-HIV-Therapien
In: Resistenz in der HIV-Therapie : Diagnostik und Management, 94-98
Part of a BookBA1BCE10F4772BF6C1256F09004B575E-NB2003b
2004Beerenwinkel, Niko[Oette, Mark]
[Kaiser, Rolf]
[Häussinger, Dieter]
Methoden zur Interpretation genotypischer Resistenztests
In: Resistenz in der HIV-Therapie : Diagnostik und Management, 66-68
Part of a Book1ECDE65F051ED39DC1256F09004AAC64-NB2003a
2004Beerenwinkel, Niko
Rahnenführer, Jörg
Däumer, Martin
Hoffmann, Daniel
Kaiser, Rolf
Selbig, Joachim
Lengauer, Thomas
[Gusfield, Dan]
[Bourne, Philip]
[Istrail, Sorin]
[Pevzner, Pavel]
[Waterman, Michael]
Learning multiple evolutionary pathways from cross-sectional data
In: RECOMB 2004 : proceedings of the Eighth Annual International Conference on Research in Computational Molecular Biology, 36-44
Proceedings Article58471DAB4FD17627C1256E150060EA62-Beerenwinkel2004a
2004Stop sign IconBeerenwinkel, Niko
Sing, Tobias
[Däumer, Martin]
[Kaiser, Rolf]
Lengauer, Thomas
[Boucher, Charles]
[Mellors, John]
[Larder, Brendan]
[Richman, Douglas]
Stop sign IconComputing the genetic barrier
In: XII International HIV Drug resistance Workshop, S125-S125
Proceedings Article90F41D4A0F62F86AC1256FB70054347F-Beerenwinkel2004Computing
2004Binsl, ThomasAttachment IconImplementation of a Generic Fragment
Based Method for Automated
Calculation of the Octanol-Water
Partition Coefficient
Universität des Saarlandes
Thesis - Bachelor thesisE73EDA451701A6A2C1257296003386EA-Binsl2004a
2004[Crass, T.]
Antes, Iris
[Basekow, R.]
[Bork, P.]
Buning, Christian
[Christensen, M.]
[Claußen, H.]
[Ebeling, C.]
[Ernst,P.]
[Gailus-Durner, V.]
[Glatting, K.-H.]
[Gohla, R.]
[Gößling, F.]
[Grote, K.]
[Heidtke, K.]
[Herrmann, A.]
[O Keefe, S.]
[Kießlich, O.]
[Kolibal, S.]
[Korbel, J.O.]
Lengauer, Thomas
[Liebich, I.]
[van der Linden, M.]
[Luz, H.]
[Meissner, K.]
[von Mering, C.]
[Mevissen, T.]
[Mewes, H.-W.]
[Michael, H.]
[Mokrejs, M.]
[Müller, T.]
[Pospisil, H.]
[Rarey, Matthias]
[Reich, J.G.]
[Schneider, R.]
[Schomburg, D.]
[Schulze-Kremer, S.]
[Schwarzer, K.]
Sommer, Ingolf
[Springstubbe, S.]
[Suhai, S.]
[Thoppae, G.]
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[Warfsmann, J.]
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2004Eyrisch, SusanneAttachment IconFun2Struc-A Tool For Predicting Protein Structure
Classes from Function Predictions
Universität des Saarlandes
Thesis - Bachelor thesis65A42C8033CB637EC125729600333829-Eyrisch2004a
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Modelling amorphous Si3B3N7: Structure and elastic properties
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Welsch, Christoph
Lengauer, Thomas
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Association of HCV-related mixed cryoglobulinemia with specific mutational patterns of the HCV E2 protein and CD81 expression on peripheral B lymphocytes
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Cellular and Molecular Characterization of Early and Late Retinal Stem Cells/Progenitors: Differential Regulation of Proliferation and Context Dependent Role of Notch Signaling
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Identification of c-Kit receptor as a regulator of adult neural stem cells in the mammalian eye: interactions with Notch signaling
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Novel technologies for virtual screening
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Wichard, J.D.
Finite iteration DT-CNN - new design and operation principles
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Ensemble methods for classification in cheminformatics
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Lengauer, Thomas
Arby: Automatic protein structure prediction using profile-profile alignment and confidence measures
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WILMA-automated annotation of protein sequences
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Hybrid clustering for microarray image analysis combining intensity and shape features
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Evolucion de la Evolucionalidad
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2004Sander, OliverLocal sequence-structure relationships in proteins
Friedrich-Alexander-Universität Erlangen-Nürnberg
Thesis - other7709CBCAA0BE5668C1256FB70046E7D7-Sander2004
2004Schlicker, AndreasAttachment IconAutomated Differential Analysis of Proteomes
Universität des Saarlandes
Thesis - Bachelor thesisAA2E3D3582987489C12572960031E8B5-Schlicker2004a
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Beerenwinkel, Niko
Lengauer, Thomas
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Learning mixtures of localized rules by maximizing the area under the ROC curve
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Domingues, Francisco S.
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Predicting Protein Structure Classes from Function Predictions
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Kämper, Andreas
Lengauer, Thomas
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In: Proceedings of the 2nd Summer School Medicinal Chemistry Regensburg 2004, 83
Poster9205A6515B1747A1C1256F9400339623-Steffen2004a
2004Stop sign IconSteffen, Andreas
Kämper, Andreas
Lengauer, Thomas
Stop sign IconFlexR - Predicting the structure of host-guest complexes
In: Proceedings of the Annual Meeting of the German Pharmaceutical Society - Joint Meeting 2004 (DPhG 2004), 130
PosterAE7C956D7E72AD19C1256F940033AB01-Steffen2004
2004[Stoll, Monika]
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Albrecht, Mario
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Lengauer, Thomas
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Genetic variation in DLG5 is associated with inflammatory bowel disease
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2004Stop sign IconTalwar, Priti
Lengauer, Thomas
Rahnenführer, Jörg
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Stop sign IconComputational Methods For Metabolite Screening
In: Proceedings of the 5th International Conference on Systems Biology (ICSB 2004), 1
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Merkwirth, Christian
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Finite iteration DT-CNN with stationary templates
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2003Albrecht, Mario
Domingues, Francisco S.
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Lengauer, Thomas
Identification of mammalian orthologs associates PYPAF5 with distinct functional roles
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Domingues, Francisco S.
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Lengauer, Thomas
Structural localization of disease-associated sequence variations in the NACHT and LRR domains of PYPAF1 and NOD2
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Structural modeling of ataxin-3 reveals distant homology to adaptins
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Pyranose oxidase identified as a member of the GMC oxidoreductase family
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Disease-associated variants in PYPAF1 and NOD2 result in similar alterations of conserved sequence
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Simple consensus procedures are effective and sufficient in secondary structure prediction
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In: Proceedings of the German Conference on Bioinformatics 2003, 13
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Bioinformatikmethoden für die Optimierung antiviraler Kombinationstherapien
In: MPG Jahrbuch, 481-486
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Estimating effective drug combinations against drug-resistant mutants from genotypes
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Tree models for the evolution of drug resistance
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2003Beerenwinkel, Niko
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Protein Function from Sequence and Structure Data
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Das, Ani V.
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A hazard based approach to dependence tests for bivariate censored models
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Ray, Somak
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New inhibitors of human cathepsin G identified by surface display library screening and peptide-protein docking
In: 7th International Symposium on Pharmaceutical Sciences (ISOPS-7), 46-49
Proceedings Article6A00BE1A732D3276C1256E190040EFCC-Ray2003
2003Stop sign IconKämper, Andreas
Lengauer, Thomas
ECLIPPSE: Environment for Chemical Library Inspection, Pre- and Postprocessing, and Screening Evaluation. User GuideManual48F0005CFAA40D79C1256D26002E05E2-KaemperLengauer2003b
2003Stop sign IconKämper, Andreas
Lengauer, Thomas
Stop sign IconVirtual Screening for novel Urease Inhibitors
In: Proceedings of the International Workshop on New Approaches in Drug Design & Discovery, 39
PosterB82FC5A7B0E226D8C1256D26002CE2C5-KaemperLengauer2003a
2003Lengauer, ThomasAnalyzing resistance phenomena in HIV with bioinformatics methods
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Combinatorial Optimization Techniques for Three-Dimensional Arrangement Problems
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Adolph, Hans-Werner
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Lactam hydrolysis catalyzed by mononuclear metallo-beta-lactamases: a density functional study
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Parallel "go with the winners algorithms" in Distributed Memory Models
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Bozinov, Daniel
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Statistical Inference for Clustering Microarrays
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Cost-effective screening for differentially expressed genes in microarray experiments based on normal mixtures
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Efficient Clustering Methods for Tumor Classification with Microarrays
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2003Stop sign IconTalwar, Priti
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In: Proceedings of the 3rd Annual Conference on Metabolic Profiling: Pathways in Discovery, 7
Proceedings Article76BD83884DE933CCC1256EA600529A9D-Talwar2003
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Lengauer, Thomas
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Software tool for automated processing of 13C labeling data from mass spectrometry data
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Sommer, Ingolf
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Profile-Profile Alignment: A Powerful Tool For Protein Structure Prediction
In: Pacific Symposium on Biocomputing, PSB 2003, 252-263
Proceedings Article80338963F1A96355C1256E1600443AC2-vonOehsen2003
2003[Wolf, Katharina]
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Beerenwinkel, Niko
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Lengauer, Thomas
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Tenofovir resistance and resensitization
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Microarrays: How many do you need?
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Molecular dynamics simulations of photoactive yellow protein (PYP) in three states of its photocycle: a comparison with X-ray and NMR data and analysis of the effects of Glu46 deprotonation and mutation
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Geno2pheno is predictive of short-term virological response
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Quantitative phenotype prediction by support vector machines
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Diversity and complexity of HIV-1drug resistance: A bioinformatics approach to predicting phenotype from genotype
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Automated Grid Alignment for High-Throughput Analysis of Microarray Images (CIIST-02)
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A hypergraph-based method for unification of existing protein structure- and sequence-families
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Lengauer, Thomas
Co-clustering of biological networks and gene expression data
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ProML - the Protein Markup Language for specification of protein sequences, structures and families
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Flexible docking under pharmacophore type constraints
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In: From Genes to Drugs via Crystallography: 33rd crytallographic course at the E. Majorana Center, 49
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2002Stop sign IconKämper, Andreas
Lengauer, Thomas
Stop sign IconDocking of Ligands into Molecular Tweezers and Molecular Clips
In: Workshop of the SFB 624 'Templates', ?-?
Poster4355EE34B0A7CAADC1256D26002E3DA5-KaemperLengauer2002b
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Stop sign IconA Fast Method for Training Support Vector Machines With a Very Large Set of Linear Features
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Predicting MHC class I epitopes in large datasets
In: BMC Bioinformatics [11], 90,1-90,11
Electronic Journal ArticleA42CFCEC4AEB3AD0C12577AE004B2646-Roomp2010a
2010Saigo, Hiroto
[Hattori, Masahiro]
[Kashima, Hisashi]
[Tsuda, Koji]
Reaction graph kernels predict EC numbers of unknown enzymatic reactions in plant secondary metabolism
In: BMC Bioinformatics [11], S31,1-S31,7
Electronic Journal ArticleDA501215119BA148C1257834004926BF-SAIGO2010
2010Weisser, Hendrik
Altmann, André
[Sierra, Saleta]
[Incardona, Francesca]
[Struck, Daniel]
[Sönnerborg, Anders]
[Kaiser, Rolf]
[Zazzi, Maurizio]
[Tschochner, Monika]
[Walter, Hauke]
Lengauer, Thomas
Only Slight Impact of Predicted Replicative Capacity for Therapy Response Prediction
In: PLoSOne [5], e9044,1-e9044,10
Electronic Journal ArticleE4B245D8EE478E3BC12577AE004B419E-Weisser2010a
2010[Wittkop, Tobias]
[Rahmann, Sven]
Baumbach, Jan
Efficient Online Transcription Factor Binding Site Adjustment by Integrating Transitive Graph Projection with MoRAine 2.0
In: Special Issue: 6th International Symposium on Integrative Bioinformatics, 117,1-117,11
Electronic Proceedings Article69446467FA6DA0FBC12577EE0055FAE6-Baumbach2010_jib
2010[Zazzi, Maurizio]
[Kaiser, Rolf]
[Sönnerborg, Anders]
[Struck, Daniel]
Altmann, Andre
[Prosperi, Mattia C. F.]
[Rosen-Zvi, Michal]
[Petroczi, Andrea]
[Peres, Yardena]
[Schülter, Eugen]
[Boucher, Charles]
[Brun-Vezinet, Francoise]
[Harigan, Richard]
[Morris, Lynn]
[Obermeier, Martin]
[Perno, Federico]
[Shafer, Robert]
[Vandamme, Anne-Mieke]
[van Laethem, Kristel]
[Wensing, Annemarie]
Lengauer, Thomas
[Incardona, Francesca]
Prediction of Response to Antiretroviral Therapy by Human Experts and by the EuResist Data-Driven Expert System (the EVE Study)
In: HIV Medicine [Early View], 1-8
Electronic Journal ArticleCCA8765C863EFD94C125782300011C7B-Zazzi2010a
2009Blankenburg, Hagen
Ramírez, Fidel
Büch, Joachim
Albrecht, Mario
DASMIweb: online integration, analysis and assessment of distributed protein interaction data
In: Nucleic Acids Research [37], W122-W128
Electronic Journal Article548AC988A29CD251C12575EC0053A799-Albrecht2009b
2009Bozek, Kasia
[Relógio, Angela]
[Kielbasa, Szymon M.]
[Heine, Markus]
[Dame, Christof]
[Kramer, Achim]
[Herzel, Hanspeter]
Regulation of clock-controlled genes in mammals.
In: PLoS One [4], e4882:1-e4882:12
Electronic Journal ArticleC1FD938CF799BA9DC12576AF003DA755-Bozek2009
2009Bozek, Kasia
Thielen, Alexander
Sierra, Saleta
[Kaiser, Rolf]
Lengauer, Thomas
V3 loop sequence space analysis suggests different evolutionary patterns of CCR5- and CXCR4-tropic HIV.
In: PLoS One [4], e7387:1-e.7387:14
Electronic Journal Article3E78745307774F07C12576AF003D495C-Bozek2009a
2009Stop sign IconMcHardy, Alice C.
Adams, Ben
Stop sign IconThe role of genomics in tracking the evolution of influenza A virus
In: PLoS Pathog [5], e1000566
Electronic Journal ArticleEE14A9F7B415D699C125781B003D46A8-McHardy2009c
2009[Zhang, Yingying]
[Rohde, Christian]
[Tierling, Sascha]
[Jurkowski, Tomasz P.]
Bock, Christoph
[Santacruz, Diana]
[Ragozin, Sergey]
[Reinhardt, Richard]
[Groth, Marco]
[Walter, Jörn]
[Jeltsch, Albert]
Attachment IconDNA methylation analysis of chromosome 21 gene promoters at single base pair and single allele resolution
In: PLoS Genetics [5], e1000438:1-e1000438:15
Electronic Journal Article6FE0F21CF33DA472C12575B2007C2F32-Zhang2009
2008Feuerbach, Lars
Christopher, Bock
Halachev, Konstantin
Büch, Joachim
Lengauer, Thomas
[Meijer, Gerrit]
[Ried, Thomas]
[Giaretti, Walter]
[Hamilton, Peter]
Towards Comparative Epigenomics: A Software Toolkit For Cross-Species Epigenome Data Analysis
In: Abstracts of the 2nd MC-GARD Meeting, 230
Electronic Proceedings ArticleDF2AEF4A18B7C00FC1257507004442BB-Feuerbach2008
2007[Kamradt, Jörn]
[Jung, Volker]
[Wahrheit, Kerstin]
Tolosi, Laura
Rahnenführer, Jörg
[Schilling, Martin]
[Walker, Robert]
[Davis, Sean]
[Stöckle, Michael]
[Meltzer, Paul]
[Wullich, Bernd]
Detection of Novel Amplicons in Prostate Cancer by Comprehensive Genomic Profiling of Prostate Cancer Cell Lines Using Oligonucleotide-Based ArrayCGH
In: PLoS ONE [2], e769
Electronic Journal Article642658E4899CA231C1257583002D4A3F-RahnenführerTolosi2007
2007Schlicker, Andreas
Rahnenführer, Jörg
Albrecht, Mario
Lengauer, Thomas
Domingues, Francisco S.
Attachment IconGOTax: investigating biological processes and biochemical activities along the taxonomic tree
In: Genome Biology [8], R33.1-10
Electronic Journal ArticleD08810EFF2A2635AC125729C0040FD74-Schlicker2007
2006Bock, Christoph
[Paulsen, Martina]
[Tierling, Sascha]
[Mikeska, Thomas]
Lengauer, Thomas
[Walter, Jörn]
Attachment IconCpG Island Methylation in Human Lymphocytes Is Highly Correlated with DNA Sequence, Repeats, and Predicted DNA Structure
In: PLoS Genetics [2], 0243-0252
Electronic Journal ArticleCDBC13700CF27425C125721F0063D22A-Bock2006b
2006Sander, Oliver
Sommer, Ingolf
Lengauer, Thomas
Local protein structure prediction using discriminative models
In: BMC Bioinformatics [7], 1-13
Electronic Journal Article38F3C8B7D7CC7569C125721E004F57C6-Sander2006
2006Schlicker, Andreas
Domingues, Francisco S.
Rahnenführer, Jörg
Lengauer, Thomas
Attachment IconA new measure for functional similarity of gene products based on Gene Ontology
In: BMC Bioinformatics [7], 1-16
Electronic Journal ArticleBF59AAAC3C285FAEC12571F500572B63-Schlicker_BMCBioinformatics_2006
2006Sommer, Ingolf
[Toppo, Stefano]
Sander, Oliver
Lengauer, Thomas
[Tosatto, Silvio C. E.]
Improving the quality of protein structure models by selecting from alignment alternatives
In: BMC Bioinformatics [7], 1-11
Electronic Journal Article5EA034C3F22F209DC125722C004C0205-Sommer2006a
2006Zhu, Hongbo
Domingues, Francisco S.
Sommer, Ingolf
Lengauer, Thomas
NOXclass: prediction of protein-protein interaction types
In: BMC Bioinformatics [7], 1-15
Electronic Journal Article644C7612915CF470C125728A0045E05C-Zhu2006
2004Rahnenführer, Jörg
Domingues, Francisco S.
Maydt, Jochen
Lengauer, Thomas
Calculating the statistical significance of changes in pathway activity from gene expression data
In: Statistical Applications in Genetics and Molecular Biology [3], Article 16
Electronic Journal Article807BF095BA983005C1256EB50045769D-Rahnenfuehrer2004a
54
Hide details for Diplomarbeiten (/Magisterarbeiten)Diplomarbeiten (/Magisterarbeiten)
2012Bader, MathiasClustering epigenetic data using a Dirichlet process prior
Universität des Saarlandes
Thesis - Masters thesisE8A202C2006A8F23C1257B2700542135-BaderMaster2012
2012Bastys, TomasAttachment IconMAP Kinase Docking Motifs in HIV Proteins
Universität des Saarlandes
Thesis - Masters thesisC3FC38B8C7592CE8C1257AF60049E3A2-Bastys2012
2012Eldarov, NasimiModeling influenza evolution in response to immune system pressure
Universität des Saarlandes
Thesis - Masters thesis9D5BA49656C17925C1257B270052B225-EldarovMaster2012
2012Kalaghatgi, PrabhavA Phylodynamic Study of HIV Transmission Networks in Europe
Universität des Saarlandes
Thesis - Masters thesis8203EA70281C0542C1257AD20059B62C-Kalaghatgi2012a
2012König, EvaAutomatic detection of loss of heterozygosity in cancer
Universität des Saarlandes
Thesis - Masters thesisB5683407CE76C544C1257B270053FCFC-KoenigMaster2012
2012Koser, SandraReconstructing anecestral methylation states in phylogenetic trees
Universität des Saarlandes
Thesis - Masters thesis9EE6F63A0286B6B0C1257B270053D7D1-KoserMaster^2012
2012Müller, JoachimExtracting pathways from biological networks incorporating omics data, introducing a webinterface for KeyPathwayMiner
Universität des Saarlandes
Thesis - Masters thesis4DD30B9F94C99DA4C1257B270052DFCB-MuellerMaster2012
2012Speicher, NoraTowards the identification of cancer subtypes by integrative clustering of molecular data
Universität des Saarlandes
Thesis - Masters thesisAE782C8688CC637CC1257B27005442DF-SpeicherMaster2012
2011Hauschild, Anne-ChristinModeling HIV Neutralization
Universität des Saarlandes
Thesis - Masters thesis662652516C4508B0C1257834003F9FD4-Hauschild2011a
2011Hoinka, Jan-MalteFinding the Hairpin in the Haystack: Towards an High Throughput in Silico Pipeline for Aptamer Motif Identification using SELEX Data
Universität des Saarlandes
Thesis - Masters thesisAB3E59A772A1FA28C1257834003F5BF1-Hoinka2011a
2011Ivanova, VioletaComparison of methods for discovering genomic aberrations relevant for cancer
Universität des Saarlandes
Thesis - Masters thesis6AA5E4BA442B3FB4C1257834003FD490-Ivanova2011a
2011Jing, CuiA comprehensive analysis of the illumina Infinium assay
Universität des Saarlandes
Thesis - Masters thesisDD6E6DB9A98C7A1CC1257834003F8B4E-Jing2011a
2011Kacprowski, TimDisease gene prioritization by combining network information and functional knowledge
Universität des Saarlandes
Thesis - Masters thesis7088F732EB1835CEC12579A500093902-Kacprowski2011
2011Weimann, AaronFunctional Profiling in Metagenomics
Universität des Saarlandes
Thesis - Masters thesis6E77E68C81F21394C1257834003FB077-Weimann2011a
2010Kuhn Cuellar, Luis EugenioA probabilistic algorithm for matching protein structures - and its application to detecting functionally relevant patterns
Universität des Saarlandes
Thesis - Masters thesis6C92695A7AE2ABEEC1257834003E67F4-Kuhn2010a
2010Loi, Luu PhucIdentifying discriminative motifs for molecular function of proteins
Universität des Saarlandes
Thesis - Masters thesisCACD93E133A5ED2AC1257834003E85EB-Loi2010a
2010Lutsik, PavloProcessing of high-throughput DNA methylation data
Universität des Saarlandes
Thesis - Masters thesis99A6CDF66EEE5836C1257834003E55C9-Lutsik2010a
2010Perner, JulianeFinding local similarities in gene expression patterns between partially reprogrammed cells and know cell types using a module network approach
Universität des Saarlandes
Thesis - Masters thesis2A58198EB323C0EFC1257834003EBAC0-Perner2010a
2010Stöckel, DanielHistory Based HIV Therapy Outcome Prediction
Universität des Saarlandes
Thesis - Masters thesis1D6E741537334AF4C12578220049D380-StoeckelMaster2010
2009Diehl, SarahAnalysis and reconstruction of protein complex topology
Universität des Saarlandes
Thesis - Masters thesisA49BC6FB29260EE6C1257834003E0F39-Diehl2009a
2009Doncheva, Nadezhda, T.Analysis and visualization of residue interaction networks
Universität des Saarlandes
Thesis - Masters thesis5D12114B57FE895EC1257834003E40EB-Doncheva2009a
2009Gwinner, FrederikAssessing the Conservation of Protein Function on Evolutionary Defined Patches
Universität des Saarlandes
Thesis - Masters thesis49CA2B7BE46D4B7EC12575750056D330-Gwinner2009
2009Müller, FabianAssessing Antibody Neutralization of HIV-1 as an Initial Step in the Search for gp160-based Immunogens
Universität des Saarlandes
Thesis - Masters thesisF95761D01E7C59E0C12578340039F9BD-Mueller2009
2009Pironti, AlejandroProbabilistic disease gene prioritization
Universität des Saarlandes
Thesis - Masters thesisDE5387F06DFF103AC1257834003E288F-Pironti2009a
2008Djoumbou, YannickMolecular Dynamics based prediction of HIV-1 drug resistance
Universität des Saarlandes
Thesis - Masters thesisEA4049F26FF9FCB9C1257577002F9E6A-Djoumbou2008
2008Fischer, SandraStructure-based prediction of HIV-1 drug resistance
Universität des Saarlandes
Thesis - Masters thesisC3C3351B147C26B9C1257577002FB77B-Fischer2008
2008Schüffler, PeterMethMarker – A toolkit for design, optimization and validation of DNA methylation biomarkers for cancer diagnosis and therapy optimization
Universität des Saarlandes
Thesis - Masters thesis3E65251BE8A70018C125757700302947-Schüffler2008
2007Bogojeska, JasminaStability analysis of oncogenetic trees mixture models
Universität des Saarlandes
Thesis - Masters thesis7A5625CE2DBE4839C1257283004617FD-Bogojeska2007a
2007Dietzen, MatthiasAn additive tree-based approach to the prediction of the strength of acidity for drug-like molecules
Universität des Saarlandes
Thesis - Masters thesis982634603B1A2969C1257577002F7D39-Dietzen2007
2007Feuerbach, LarsAttachment IconTowards Comparative Epigenomics: A Pilot Study on DNA Methylation of CpG Islands on Human Chromosome 21
Universität des Saarlandes
Thesis - Masters thesis1F17F22E9E474819C12575750035A81D-Feuerbach2007
2007Haid, CarlaBSIFlex: Binding Site Identification including protein flexibility
Universität des Saarlandes
Thesis - Masters thesisF019912A8A684C8EC1257577002FC9A1-Haid2007
2007Kircher, MartinIn silico analysis of microRNA genes on human chromosome 14 and mouse chromosome 12
Universität des Saarlandes
Thesis - Masters thesis2707F3C4E83AB296C1257577002FE6C2-Kircher2007
2007Korbel, Ulli S.Identification of Symmetries in Molecules and Complexes
Universität des Saarlandes
Thesis - Masters thesis30BBF52968F3F349C1257577002FFFBE-Korbel2007
2007Müller, OliverUsing Shape Retrieval Techniques for Identifying Similar Protein Binding Sites
Universität des Saarlandes
Thesis - Masters thesis5415E8A7611721F1C125728400339301-Mueller2006
2007Schelhorn, Sven-EricPrediction of Domain and Motif Interactions from Protein Networks
Universität des Saarlandes
Thesis - Masters thesisBC8ABDF4D878B0E0C1257577002F447B-Schelhorn2007
2007Volkamer, AndreaAutomated generation of pharmacophore type constraints to improve FlexX docking
Universität des Saarlandes
Thesis - Masters thesisFC468FE5125A8FCAC125757700304971-Volkamer2007
2007Weisser, HendrikEstimating the local variance of protein structure models
Universität des Saarlandes
Thesis - Masters thesis75990C0424B4A097C12575750056B030-Weisser2007
2006Assenov, YassenTopological Analysis of Biological
Networks
Universität des Saarlandes
Thesis - Masters thesis7C34F302699CE873C12572960035F334-Assenov2006a
2006Binsl, ThomasFeature Prints: A new method for calculating molecular similarities
Universität des Saarlandes
Thesis - Masters thesis9BCD7C5249B9E51AC1257220004855B1-Binsl2006a
2006Guo, XinImproving Fold Recognition Using Protein
and Domain Interactions
Universität des Saarlandes
Thesis - Masters thesisC9EF4A035F20034DC12572960035C585-Guo2006a
2006Halachev, KonstantinEpiGRAPHregression: A toolkit for (epi-)genomic correlation analysis and prediction of quantitative attributes
Universität des Saarlandes
Thesis - Masters thesis56DA5A90E26AE559C12572350051361B-HalachevMaster2006
2006Kaspar, MelanieAutomated conformational analysis of macrocyclic ring systems
Universität des Saarlandes
Thesis - Masters thesis57A94B416CA8D4E9C12572200047FAC2-Kaspar2006a
2006Thielen, AlexanderPrediction of linear B-cell epitopes and MHC class II binding peptides
Eberhardt-Karls-Universität Tübingen
Thesis - Masters thesis01C3C87B3FF765B1C125723500305EF0-Thielen2006
2006Tolosi, LauraAnalysis of Array CGH Data for the Estimation of Genetic Tumor Progression
Universität des Saarlandes
Thesis - Masters thesis0EA512C11180051FC12572350050DF02-Tolosi2006
2006Weinhold, NilsInference of Protein Function based on Functionally Conserved Regions in Sequence and Structure Space
Universität des Saarlandes
Thesis - Masters thesis68EDF9861A7F90A8C125728400337076-Weinhold2006
2005Alexa, AdrianIntegrating the GO graph structure in scoring the
significance of Gene Ontology terms
Universität des Saarlandes
Thesis - Masters thesis5423BA8EA287FC1EC1257296003505D6-Alexa2005a
2005Ifrim, GeorgianaA Bayesian Learning Approach to Concept-Based Document Classification
Universität des Saarlandes
Thesis - Masters thesis2B45D00ABB3EABC0C1257BFF00235978-?
2005Schlicker, AndreasA Global Approach to Comparative Genomics: Comparison of Functional Annotation over the Taxonomic Tree
Universität des Saarlandes
Thesis - Masters thesis76B88A36B2C63828C12570EB004472E7-Schlicker2005
2005Siu, Shirley Weng-InComputational prediction of MHC-peptide interactions
Universität des Saarlandes
Thesis - Masters thesis50C9778A66DE6C91C12570DF00472360-Siu2005
2005Yin, JunmingModel Selection for Mixtures of Mutagenetic Trees
Universität des Saarlandes
Thesis - Masters thesis0F41FDC343B3572BC12572960035A075-Yin2005a
2004Bayjanov, JumamuratScoring pathway activity from gene
expression data
Universität des Saarlandes
Thesis - Masters thesisBC41BF7CA33F2317C1257296003534ED-Bayjanov2004a
2004Ramírez, FidelHacia una comprension de la accion de la recombinacion genetica y la mutacion en el origen de la variacion fenotipica, mediante el analisis de la computacion evolutiva
Universidad Nacional de Colombia
Thesis - Masters thesis9A00F2BC63B1C36DC125726D004BD118-Ramirez2004_thesis
2004Sing, TobiasLearning localized rule mixtures by maximizing the area under the ROC curve, with an application to the prediction of HIV-1 coreceptor usage
Universität Freiburg
Thesis - Masters thesisCADB1B353BE24C44C1256FB70051E86E-Sing2004a
2004Trajkovski, IgorAnalysis of protein binding pocket flexibility
Universität des Saarlandes
Thesis - Masters thesisFE9E2234859B9C8BC1256FBD005A29E8-Trajkovski2004
21
Hide details for DissertationenDissertationen
2013Patil, Kaustubh RaosahebGenome Signature based Sequence Comparison for Taxonomic Assignment and tree inference
Universität des Saarlandes
Thesis - PhD thesis58D1B1989200E496C1257BFF002517BF-Patil2013
2012Ramirez, FidelNovel Approaches to the Integration and Analysis of Systems Biology
Universität des Saarlandes
Thesis - PhD thesisEAA85644FD5EB9F8C1257B2800408A00-Ramirez2012th
2012Tolosi, LauraFinding Regions of Aberrant DNA Copy Number Associated With Tumor Phenotype
Universität des Saarlandes
Thesis - PhD thesis8E6F4087F836C766C1257B280040B1E2-Tolosi2012th
2011Bogojeska, JasminaAttachment IconStatistical Learning Methods for Bias-aware HIV Therapy Screening
Universität des Saarlandes
Thesis - PhD thesisB354E6F7403CA747C1257975005027FD-BogojeskaPhD2011
2011Bozek, KatarzynaAttachment IconAnalysis of HIV-host interaction on different scales.
Universität des Saarlandes
Thesis - PhD thesisD454DEBABE060435C125798100144241-BozekDiss2011
2011Emig, DorotheaNovel analysis approaches to context-dependent molecular networks
Universität des Saarlandes
Thesis - PhD thesisE1ADC0DDC6CE7F89C12579A5000A2C91-Emig2011
2011Kunert, LarsMaximal Common Subgraph DAGs: Theory and Application to Virtual Screening in Drug Development
Universität des Saarlandes
Thesis - PhD thesisA739E601E6423A92C12578340040221B-Kunert2010a
2011Thielen, AlexanderGenotypic Analysis of HIV-1 Coreceptor Usage
Universität des Saarlandes
Thesis - PhD thesisD95B13CBBC2F24FCC12579A30050374D-Thielen2011diss
2010Altmann, AndréBioinformatical approaches to ranking of anti-HIV combination therapies and planning of treatment schedules
Universität des Saarlandes
Thesis - PhD thesis141A5B192249AA0DC12578230059F631-Altmann2010
2010Johannsen, DanielRandom Combinatorial Structures and Randomized Search Heuristics
Universität des Saarlandes
Thesis - PhD thesisC045DCEBE7A76162C1257BFF0024BB3A-?
2010Schlicker, AndreasAttachment IconOntology-based Similarity Measures and their Application in Bioinformatics
Universität des Saarlandes
Thesis - PhD thesisE9C50306DF804193C12577EB00373178-Schlicker2010
2010Zhu, HongboCharacterization, classification and alignment of protein-protein interfaces
Universität des Saarlandes
Thesis - PhD thesisF18C31CDC42018BBC1257834004000B5-Zhu2010a
2008Bock, ChristophComputational Epigenetics - Bioinformatic methods for epigenome prediction, DNA methylation mapping and cancer epigenetics
Universität des Saarlandes
Thesis - PhD thesis49DE16446B8011EBC12575220079E05D-Bock2008b
2008Hartmann, ChristophModeling of Flexible Side Chains for Protein-Ligand Docking
Universität des Saarlandes
Thesis - PhD thesis3968192B66461AB1C125757600399042-hartmann2008
2008Maydt, JochenAnalysis of recombination in Molecular Sequence Data
Universität des Saarlandes
Thesis - PhD thesisFAC475000E9090CDC12575750032B7E8-maydt2008
2008Sander, OliverStructural Descriptors for the Analysis of Protein Structure, Function, and Evolution
Universität des Saarlandes
Thesis - PhD thesisCF8D773596E2FB15C12575700059E36E-SanderDiss2008
2008Sing, TobiasModel-Based Anti HIV Therapy
Universität des Saarlandes
Thesis - PhD thesis6016CCAE973E4D56C125757500328979-sing2008
2008Steffen, AndreasComputational Approaches in Supramolecular Chemistry with a special Focus on Virtual Screening
Universität des Saarlandes
Thesis - PhD thesis254F8F4BDCBF09CEC125757500326827-steffen2008a
2008Talwar, PritiDevelopment of Computational Methods for Metabolic Network Analysis based on Metabolomics Data
Universität des Saarlandes
Thesis - PhD thesis745DAA12D6A3C533C125757500329E62-talwar2008
2006Albrecht, MarioCombining protein structure prediction with experiments and functional information
Universität des Saarlandes
Thesis - PhD thesis96422E3C0D0A2190C125729600409EA0-Albrecht2006i
2003Beerenwinkel, NikoAttachment IconComputational Analysis of HIV Drug Resistance Data
Universität des Saarlandes
Thesis - PhD thesis02E4D5734B6ED7C3C12572960040D6F8-Beerenwinkel2003g
3
Hide details for HabilitationenHabilitationen
2009Antes, IrisComputational Methods for the Investigation of Protein-Ligand Interactions
Universität des Saarlandes
Thesis - Habilitation thesis77F6E74B2985B282C12575750032CCF1-antes2009
2009Sommer, IngolfAttachment IconFrom Protein Structure to Function
Universität des Saarlandes
Thesis - Habilitation thesis975F52B7D7D7BF97C1257834003DB901-Sommer2010
2006Rahnenführer, JörgStatistical methods for the biological interpretation of genome-wide measurements
Universität des Saarlandes
Thesis - Habilitation thesisD187AFB221662AC4C12572350038E3D6-Rahnenfuehrer2006Habil
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