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TitleAuthor(s) [non member]Editor(s) [non member]YearType
A Bayesian Learning Approach to Concept-Based Document Classification
Universität des Saarlandes
Ifrim, Georgiana2005Thesis - Masters thesis
A classical dynamics study of the unbinding of ATP from the F0F1-ATPase
In: Poster book of the European Conference on Computational Biology, Saarbrücken, Germany 2002, -
Antes, Iris
[Chandler, David]
[Oster, George]
2002Poster
A comprehensive analysis of the illumina Infinium assay
Universität des Saarlandes
Jing, Cui2011Thesis - Masters thesis
A Computational Method for Predicting First-Line Antiretroviral Therapy Success
In: Abstract Book. 9th Workshop on HIV & Hepatitis Treatment Strategies & Antiviral Drug Resistance, 94
Pironti, Alejandro
Altmann, André
Büch, Joachim
Lengauer, Thomas
2011Poster
A Distributed Annotation System for Molecular Interactions
Ruprecht Karl Universität Heidelberg; Universität Heilbronn
Blankenburg, Hagen2007Thesis - other
A DNA methylation fingerprint of 1628 human samples
In: Genome Research [22], 407-419
[Fernandez, Agustin F.]
Assenov, Yassen
[Martin-Subero, Jose Ignacio]
[Balint, Balazs]
[Siebert, Reiner]
[Taniguchi, Hiroaki]
[Yamamoto, Hiroyuki]
[Hidalgo, Manuel]
[Tan, Aik-Choon]
[Galm, Oliver]
[Ferrer, Isidre]
[Sanchez-Cespedes, Montse]
[Villanueva, Alberto]
[Carmona, Javier]
[Sanchez-Mut, Jose V.]
[Berdasco, Maria]
[Moreno, Victor]
[Capella, Gabriel]
[Monk, David]
[Ballestar, Esteban]
[Ropero, Santiago]
[Martinez, Ramon]
[Sanchez-Carbayo, Marta]
[Prosper, Felipe]
[Agirre, Xabier]
[Fraga, Mario F.]
[Gran˜a, Osvaldo]
[Perez-Jurado, Luis]
[Mora, Jaume]
[Puig, Susana]
[Prat, Jaime]
[Badimon, Lina]
[Puca, Annibale A.]
[Meltzer, Stephen J.]
Lengauer, Thomas
[Bridgewater, John]
Bock, Christoph
[Esteller, Manel]
2012Journal Article
A Fast Method for Training Support Vector Machines With a Very Large Set of Linear Features
In: Proceedings of the International Conference on Multimedia and Expo, 309-312
Maydt, Jochen
[Lienhart, Rainer]
2002Proceedings Article
A Fully Computational Model for Predicting Percutaneous Drug Absorption
In: Journal of Chemical Information and Modeling [1], 424-429
[Neumann, Dirk]
[Kohlbacher, Oliver]
[Merkwirth, Christian]
Lengauer, Thomas
2006Journal Article
A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1
In: Nature Genetics [39], 207-211
[Hampe, Jochen]
[Franke, Andre]
[Rosenstiel, Philip]
[Till, Andreas]
[Teuber, Markus]
[Huse, Klaus]
Albrecht, Mario
Mayr, Gabriele
[De La Vega, Francisco M.]
[Briggs, Jason]
[Günther, Simone]
[Prescott, Natalie J.]
[Onnie, Clive M.]
[Häsler, Robert]
[Sipos, Bence]
[Fölsch, Ulrich R.]
Lengauer, Thomas
[Platzer, Matthias]
[Mathew, Christopher G.]
[Krawczak, Michael]
[Schreiber, Stefan]
2007Journal Article
A Global Approach to Comparative Genomics: Comparison of Functional Annotation over the Taxonomic Tree
Universität des Saarlandes
Schlicker, Andreas2005Thesis - Masters thesis
A hazard based approach to dependence tests for bivariate censored models
In: Mathematical Methods in Statistics [11], 297-322
[Janssen, A.]
Rahnenführer, Jörg
2003Journal Article
A highly ordered network of HIV-1 RT mutations regulates the continuous escape from antiviral drugs
In: International Workshop in HIV Dynamics and Evolution, -
[Svicher, Valentina]
[Ceccherini-Silberstein, Francesca]
Sing, Tobias
[Santoro, Maria Mercedes]
[Gori, C.]
Beerenwinkel, Niko
[Gago, F.]
[D'Arrigo, R.]
[Bellochi, M.C.]
[Giannella, S.]
[Bertoli, A.]
[D'Arminio Monforte, A.]
[Antinori, A.]
[Perno, Carlo-Federico]
2005Proceedings Article
A hypergraph-based method for unification of existing protein structure- and sequence-families
In: In Silico Biology [2], 339 - 349
[Freudenberg, Jan]
[Zimmer, Ralf]
[Hanisch, Daniel]
Lengauer, Thomas
2002Journal Article
A large-scale evaluation of computational protein function prediction
In: Nature Methods [10], 221-227
[Radivojac, Predrag]
[Clark, Wyatt T]
[Oron, Tal Ronnen]
[Schnoes, Alexandra M]
[Wittkop, Tobias]
[Sokolov, Artem]
[Graim, Kiley]
[Funk, Christopher]
[Verspoor, Karin]
[Ben-Hur, Asa]
[Pandey, Gaurav]
[Yunes, Jeffrey M]
[Talwalkar, Ameet S]
[Repo, Susanna]
[Souza, Michael L]
[Piovesan, Damiano]
[Casadio, Rita]
[Wang, Zheng]
[Cheng, Jianlin]
[Fang, Hai]
[Gough, Julian]
[Koskinen, Patrik]
[T\"{o}r\"{o}nen, Petri]
[Nokso-Koivisto, Jussi]
[Holm, Liisa]
[Cozzetto, Domenico]
[Buchan, Daniel W A]
[Bryson, Kevin]
[Jones, David T]
[Limaye, Bhakti]
[Inamdar, Harshal]
[Datta, Avik]
[Manjari, Sunitha K]
[Joshi, Rajendra]
[Chitale, Meghana]
[Kihara, Daisuke]
[Lisewski, Andreas M]
[Erdin, Serkan]
[Venner, Eric]
[Lichtarge, Olivier]
[Rentzsch, Robert]
[Yang, Haixuan]
[Romero, Alfonso E]
[Bhat, Prajwal]
[Paccanaro, Alberto]
[Hamp, Tobias]
[Ka\ss ner, Rebecca]
[Seemayer, Stefan]
[Vicedo, Esmeralda]
[Schaefer, Christian]
[Achten, Dominik]
[Auer, Florian]
[Boehm, Ariane]
[Braun, Tatjana]
[Hecht, Maximilian]
[Heron, Mark]
[H\"{o}nigschmid, Peter]
[Hopf, Thomas A]
[Kaufmann, Stefanie]
[Kiening, Michael]
[Krompass, Denis]
[Landerer, Cedric]
[Mahlich, Yannick]
[Roos, Manfred]
[Bj\"{o}rne, Jari]
[Salakoski, Tapio]
[Wong, Andrew]
[Shatkay, Hagit]
Gatzmann, Fanny
Sommer, Ingolf
[Wass, Mark N]
[Sternberg, Michael J E]
[Skunca, Nives]
[Supek, Fran]
[Bo\v{s}njak, Matko]
[Panov, Pan\v{c}e]
[D\v{z}eroski, Sa\v{s}o]
[Smuc, Tomislav]
[Kourmpetis, Yiannis A I]
[van Dijk, Aalt D J]
[Braak, Cajo J F Ter]
[Zhou, Yuanpeng]
[Gong, Qingtian]
[Dong, Xinran]
[Tian, Weidong]
[Falda, Marco]
[Fontana, Paolo]
[Lavezzo, Enrico]
[{Di Camillo}, Barbara]
[Toppo, Stefano]
[Lan, Liang]
[Djuric, Nemanja]
[Guo, Yuhong]
[Vucetic, Slobodan]
[Bairoch, Amos]
[Linial, Michal]
[Babbitt, Patricia C]
[Brenner, Steven E]
[Orengo, Christine]
[Rost, Burkhard]
[Mooney, Sean D]
[Friedberg, Iddo]
2013Journal Article
A method for finding consensus breakpoints in the cancer genome from copy number data
In: Bioinformatics [29], 1793-1800
Tolosi, Laura
[Theißen, J.]
Halachev, Konstantin
[Hero, B.]
[Berthold, F.]
Lengauer, Thomas
2013Journal Article
Attachment IconA network-based analysis of polyanion-binding proteins utilizing human protein arrays
In: Journal of Biological Chemistry [282], 10153-10163
[Salamat-Miller, Nazila]
[Fang, Jianwen]
[Seidel, Christopher W.]
Assenov, Yassen
Albrecht, Mario
[Middaugh, C. Russell]
2007Journal Article
A network-based analysis of polyanion-binding proteins utilizing yeast protein arrays
In: Molecular and Cellular Proteomics [5], 2263-2278
[Salamat-Miller, Nazila]
[Fang, Jianwen]
[Seidel, Christopher W.]
[Smalter, Aaron M.]
[Assenov, Yassen]
Albrecht, Mario
[Middaugh, C. Russell]
2006Journal Article
A new CARD15 mutation in Blau syndrome
In: European Journal of Human Genetics [13], 742-747
[Van Duist, Marjan M.]
Albrecht, Mario
[Podswiadek, Marta]
[Giachino, Daniela]
Lengauer, Thomas
[Punzi, Leonardo]
[De Marchi, Mario]
2005Journal Article
Attachment IconA new measure for functional similarity of gene products based on Gene Ontology
In: BMC Bioinformatics [7], 1-16
Schlicker, Andreas
Domingues, Francisco S.
Rahnenführer, Jörg
Lengauer, Thomas
2006Electronic Journal Article
A new method for the fast solution of protein-3D-structures, combining experiments and bioinformatics
In: Coupling of Biological and Electronic Systems: Proceedings of the 2nd Caesarium, Bonn, 1-3 November 2000, 59-78
[Hoffmann, Daniel]
[Schnaible, Volker]
[Wefing, Stephan,]
Albrecht, Mario
[Hanisch, Daniel]
[Zimmer, Ralf]
[Hoffmann, Karl-Hein]2002Proceedings Article
A Phylodynamic Study of HIV Transmission Networks in Europe
Universität des Saarlandes
Kalaghatgi, Prabhav2012Thesis - Masters thesis
Attachment IconA Prefiltering Method to Speed up Protein
Structure Prediction
Universität des Saarlandes
Immesberger, Stefan2005Thesis - Bachelor thesis
A probabilistic algorithm for matching protein structures - and its application to detecting functionally relevant patterns
Universität des Saarlandes
Kuhn Cuellar, Luis Eugenio2010Thesis - Masters thesis
A Prognostic DNA Methylation Signature for Stage I Non-Small-Cell Lung Cancer
In: Journal of Clinical Oncology [31], 4140-4147
[Sandoval, Juan]
[Mendez-Gonzales, Jesus]
[Nadal, Ernest]
[Chen, Guoan]
[Carmona, F. Javier]
[Sayols, Sergi]
[Moran, Sebastian]
[Heyn, Holger]
[Vizoso, Miguel]
[Gomez, Antonio]
[Sanchez-Cespedes, Montse]
Assenov, Yassen
Müller, Fabian
Bock, Christoph
[Taron, Miquel]
[Mora, Josefina]
[Muscarella, Lucia A.]
[Liloglou, Triantafillos]
[Davies, Michael]
[Pollan, Marina]
[Pajares, Maria J.]
[Torre, Wenceslao]
[Montuenga, Luis M.]
[Brambilla, Elisabeth]
[Field, John K.]
[Roz, Luca]
[Lo Iacono, Marco]
[Scagliotti, Giorgio V.]
[Rosell, Rafael]
[Beer, David G.]
[Esteller,Manel]
2013Journal Article
A promoter DNA demethylation landscape of human hematopoietic differentiation
In: Nucleic Acids Research [40], 116-131
[Calvanese, Vincenzo]
[Fernandez, Agustín F.]
[Urdinguio, Rocío G.]
[Suarez-Álvarez, Beatriz]
[Mangas, Cristina]
[Pérez-García, Vicente]
[Bueno, Clara]
[Montes, Rosa]
[Ramos-Mejía, Verónica]
[Martínez-Camblor, Pablo]
[Ferrero, Cecilia]
Assenov, Yassen
Bock, Christoph
[Menendez, Pablo]
[Carrera, Ana Clara]
[Lopez-Larrea, Carlos]
[Fraga, Mario F.]
2012Journal Article
A single amino acid substitution of the human immunodeficiency virus type 1 capsid protein affects viral sensitivity to TRIM5 alpha.
In: Retrovirology [7], 58,1-58,10
[Kuroishi, Ayumu]
Bozek, Katarzyna
[Shioda, Tatsuo]
[Nakayama, Emi E.]
2010Electronic Journal Article
A singular value decomposition approach for improved taxonomy classification of biological sequences
In: BMC Genomics [12], S11,1-S11,15
[Santos, Anderson R]
[Santos, Marcos A]
Baumbach, Jan
[McCulloch, John A]
[Oliveira, Guilherme C]
[Silva, Artur]
[Miyoshi, Anderson]
[Azevedo, Vasco]
2011Journal Article
ABCA1 regulatory variants influence coronary artery disease independent of effects on plasma lipid levels
In: Clinical Genetics [61], 115-125
[Zwarts, K.Y.]
[Clee, Susanne M.]
[Zwinderman, A.H.]
[Engert, J.C.]
[Singaraja, Roshni]
[Loubser, O]
[James, E]
Roomp, Kirsten
[Hudson, T.J.]
[Jukema, J.W.]
[Kastelein, J.J.P.]
[Hayden, Michael R.]
2002Journal Article
Added value of deep sequencing relative to population sequencing in heavily pre-treated HIV-1-infected subjects
In: PLoS One [6], e19461,1-e19461,5
[Codoner, Francisco]
[Pou, Christian]
Thielen, Alexander
[García, Federico]
[Delgado, Rafael]
[Dalmau, David]
[Álvarez-Tejado, Miguel]
[Ruiz, Lidia]
[Clotet, Bonaventura]
[Paredes, Roger]
2011Electronic Journal Article
Additional Mutations in HIV-1 Reverse Transcriptase are Involved in the Highly Ordered Regulation of NRTI Resistance
In: Proceedings of the 3rd European HIV Drug Resistance Workshop, -
[Svicher, Valentina]
[Ceccherini-Silberstein, Francesca]
Sing, Tobias
[Santoro, Maria Mercedes]
[Gori, C.]
Beerenwinkel, Niko
[Gago, F.]
[D'Arrigo, R.]
[Bellocchi, M. C.]
[Giannella, S.]
[Bertoli, A.]
[D'Arminio Monforte, A.]
[Antinori, A.]
[Perno, Carlo-Federico]
2005Proceedings Article
Advantages of Predicted Phenotypes and Statistical Learning Models in Inferring Virological Response to Antiretroviral Therapy from HIV Genotype
In: Antiviral Therapy [14], 273-283
Altmann, André
Sing, Tobias
[Vermeiren, Hans]
[Winters, Bart]
[Van Craenenbroeck, Elke]
[Van der Borght, Koen]
[Rhee, Soo-Yon]
Shafer, Robert W.
[Schülter, Eugen]
[Kaiser, Rolf]
[Peres, Yardena]
[Sönnerborg, Anders]
Fessel, W. Jeffrey
[Incardona, Francesca]
[Zazzi, Maurizio]
[Bacheler, Lee]
[Van Vlijmen, Hermann]
Lengauer, Thomas
2009Journal Article
Age and residual cholesterol efflux affect HDL cholesterol levels and coronary artery disease in ABCA1 heterozygotes
In: Journal of Clinical Investigation [106], 1263-70
[Clee, Susanne M.]
[Kastelein, J.J.P.]
[van Dam, M]
[Marcil, Michel]
Roomp, Kirsten
[Zwarts, K.Y.]
[Collins, Jennifer A.]
[Roelants, R]
[Tamasawa, N]
[Stulc, T]
[Suda, T]
[Ceska, R]
[Boucher, B]
[Rondeau, C]
[DeSouich, C]
[Brooks-Wilson, A]
[Molhuizen, H.O.]
[Frohlich, J]
[Genest, Jacques Jr]
[Hayden, Michael R.]
2000Journal Article
Attachment IconAlignment of Non-Covalent Interactions at Protein-Protein Interfaces
In: PLoS ONE [3], e1926
Zhu, Hongbo
Sommer, Ingolf
Lengauer, Thomas
Domingues, Francisco S.
2008Journal Article
AltAnalyze and DomainGraph: analyzing and visualizing exon expression data
In: Nucleic Acids Research [38], W755-W762
Emig, Dorothea
[Salomonis, Nathan]
[Baumbach, Jan]
Lengauer, Thomas
[Conklin, Bruce R.]
Albrecht, Mario
2010Journal Article
Alternative Binding Modes of Polyproline Peptides Binding to the GYF Domain
In: Biochemistry [44], 6404-6415
[Gu, Wei]
[Kofler, Michael]
Antes, Iris
[Freund, Christian]
[Helms, Volkhard]
2005Journal Article
Amino acid variations in hepatitis C virus p7 and sensitivity to antiviral combination therapy with amantadine in chronic hepatitis C
In: Antiviral Therapy [11], 507-519
[Mihm, Ulrike]
[Grigorian, Natalia]
[Welsch, Christoph]
[Herrmann, Eva]
[Kronenberger, Bernd]
[Teuber, Gerlinde]
[von Wagner, Michael]
[Hofmann, Wolf-Peter]
Albrecht, Mario
Lengauer, Thomas
[Zeuzem, Stefan]
[Sarrazin, Christoph]
2006Journal Article
An additive tree-based approach to the prediction of the strength of acidity for drug-like molecules
Universität des Saarlandes
Dietzen, Matthias2007Thesis - Masters thesis
An arginine/lysine-rich motif is crucial for VCP/p97-mediated modulation of ataxin-3 fibrillogenesis
In: EMBO Journal [25], 1547-1558
[Boeddrich, Annett]
[Gaumer, Sébastien]
[Haacke, Annette]
[Tzvetkov, Nikolay]
Albrecht, Mario
[Evert, Bernd O.]
[Müller, Eva C.]
[Lurz, Rudi]
[Breuer, Peter]
[Schugardt, Nancy]
[Plaßmann, Stephanie]
[Xu, Kexiang]
[Warrick, John M.]
[Suopanki, Jaana]
[Wüllner, Ullrich]
[Frank, Ronald]
[Hartl, Ulrich F.]
[Bonini, Nancy M.]
[Wanker, Erich E.]
2006Journal Article
An exhaustive methode for CpG island annotation
In: Special Issue: Abstracts of the 3rd MC-GARD Meeting, 146-146
Feuerbach, Lars
Halachev, Konstantin
Lengauer, Thomas
Bock, Christoph
[Meijer, Gerrit]
[Ried, Thomas]
[Giaretti, Walter]
[Hamilton, Peter]
2009Poster
An expanded model of HIV cell entry phenotype based on multi-parameter single-cell data
In: Retrovirology [9], 60.1-60.15
Bozek, Katarzyna
[Eckhardt, Manon]
[Sierra, Saleta]
[Kaiser, Rolf]
[Kräusslich, Hans-Georg]
[Müller, Barbara]
Lengauer, Thomas
2012Journal Article
An Extended Set of Haar-like Features for Rapid Object Detection
In: Proceedings of the International Conference on Image Processing, 900-903
[Lienhart, Rainer]
Maydt, Jochen
2002Proceedings Article
An integrative approach for predicting interactions of protein regions
In: Bioinformatics [24], i35-i41
Schelhorn, Sven-Eric
Lengauer, Thomas
Albrecht, Mario
2008Journal Article
An integrative approach to gain insights into the cellular function of human ataxin-2
In: Journal of Molecular Biology [346], 203-214
[Ralser, Markus]
Albrecht, Mario
[Nonhoff, Ute]
Lengauer, Thomas
[Lehrach, Hans]
[Krobitsch, Sylvia]
2005Journal Article
An Integrative Clinical Database and Diagnostics Platform for Biomarker Identification and Analysis in Ion Mobility Spectra of Human Exhaled Air
In: Journal of Integrative Bioinformatics [10],
[Schneider, Till]
Hauschild, Anne-Christin
[Baumbach, Joerg Ingo]
Baumbach, Jan
2013Electronic Journal Article
Analysing and interpreting DNA methylation data
In: Nature Reviews Genetics [13], 705-719
Bock, Christoph2012Journal Article
Attachment IconAnalysis and Prediction of Helix Shift Errors in Homology Modeling
In: In Silico Biology [6], 131-145
Bock, Christoph
[Hesser, Jürgen]
2006Journal Article
Analysis and prediction of protein-protein-interaction types
In: BMC Bioinformatics [7], -
Lengauer, Thomas
Domingues, F.S.
Sommer, Ingolf
Zhu, Hongbo
2006Journal Article
Analysis and prediction of protein-protein interaction types
In: 4th European Conference on Computational Biology (ECCB05), 1
Zhu, Hongbo
Domingues, Francisco S.
Sommer, Ingolf
Lengauer, Thomas
2005Poster
Analysis and reconstruction of protein complex topology
Universität des Saarlandes
Diehl, Sarah2009Thesis - Masters thesis
Analysis and visualization of residue interaction networks
Universität des Saarlandes
Doncheva, Nadezhda, T.2009Thesis - Masters thesis
Analysis of Array CGH Data for the Estimation of Genetic Tumor Progression
Universität des Saarlandes
Tolosi, Laura2006Thesis - Masters thesis
Analysis of Expression Data: Classification of genes
In: Bioinformatics - From Genomes to Therapies 2. Getting at the Inner Workings: Molecular Interactions, 993-1021
Rahnenführer, Jörg
Lengauer, Thomas
Lengauer, Thomas2007Part of a Book
Attachment IconAnalysis of HIV-host interaction on different scales.
Universität des Saarlandes
Bozek, Katarzyna2011Thesis - PhD thesis
Attachment IconAnalysis of Mutations in the Death Domains, Death Effector Domains, Caspase
Recruitment Domains, and Pyrin Domains
Universität des Saarlandes
Yalak, Garif2005Thesis - Bachelor thesis
Analysis of physicochemical and structural properties determining HIV-1 coreceptor usage
In: PLoS Computational Biology [x], x
[Bozek, K.]
Lengauer, Thomas
[Sierra, S.]
[Kaiser, Rolf]
[Domingues, F.S.]
2013Journal Article
Analysis of protein binding pocket flexibility
Universität des Saarlandes
Trajkovski, Igor2004Thesis - Masters thesis
Analysis of protein complexes and tissue-spedific expression
Universität des Saarlandes
Kacprowski, Tim2010Thesis - Bachelor thesis
Analysis of quality raw data of second generation sequencers with Quality Assessment Software
In: BMC Research Notes [4], 130,1-130,6
[Ramos, Rommel T.J.]
[Carneiro, Adriana R.]
Baumbach, Jan
[Azevedo, Vasco]
[Schneider, Maria P.C.]
[Silva, Artur]
2011Journal Article
Analysis of recombination in Molecular Sequence Data
Universität des Saarlandes
Maydt, Jochen2008Thesis - PhD thesis
Analyzing and visualizing residue networks of protein structures
In: Trends in Biochemical Sciences [36], 179-182
Doncheva, Nadezhda T.
[Klein, Karsten]
Domingues, Francisco S.
Albrecht, Mario
2011Journal Article
Analyzing epigenome data in context of genome evolution and human diseases
In: Evolutionary Genomics : Statistical and Computational Methods, Volume 2, 431-467
In: Methods of Molecular Biology [856], 431-467
[Feuerbach, Lars]
Halachev, Konstantin
Assenov, Yassen
Mueller, Fabian
Bock, Christoph
Lengauer, Thomas
[Anisimova, Maria]2012Part of a Book
Analyzing resistance phenomena in HIV with bioinformatics methods
In: Bioinformatics [19], 92i
Lengauer, Thomas2003Journal Article
Ancestral germline methylation reconstruction of young repeats
In: Transcription, chromatin structure and DNA repair in development and differentiation, 81
Feuerbach, Lars
Lengauer, Thomas
2010Poster
Antiretroviral Therapy Optimisation without Genotype Resistance Testing: A Perspective on Treatment History Based Models
In: PLoS ONE [5], e13753,1-e13753,8
[Prosperi, Mattia C. F.]
[Rosen-Zvi, Michal]
Altmann, Andre
[Zazzi, Maurizio]
[Di Giambenedetto, Simona]
[Kaiser, Rolf]
[Schülter, Eugen]
[Struck, Daniel]
[Sloot, Peter]
[van de Vijver, David A.]
[Vandamme, Anne-Mieke]
[Sönnerborg, Anders]
2010Electronic Journal Article
APOBEC3G/F a one possible driving source for co-receptor switch of the human immunodeficiency virus-1
In: Medical Microbiology and Immunology [201], 7-16
[Heger, Eva]
[Thielen, Alexander]
[Gilles, Ramona]
[Obermeier, Martin]
Lengauer, Thomas
[Kaiser, Rolf]
[Trapp, Susanna]
2012Journal Article
APOBEC3G/F as one possible driving force for co-receptor switch of the human immunodeficiency virus-1
In: Medical Microbiology and Immunology [201], 7-16
[Heger, Eva]
Thielen, Alexander
[Gilles, Ramona]
[Obermeier, Martin]
Lengauer, Thomas
[Kaiser, Rolf]
[Trapp, Susanna]
2011Journal Article
Application of oncogenetic trees mixtures as a biostatistical model of the clonal cytogenetic evolution of meningiomas
In: International Journal of Cancer [121], 1473-1480
[Ketter, Ralf]
[Urbschat, Steffi]
[Henn, Wolfram]
[Feiden, Wolfgang]
Beerenwinkel, Niko
Lengauer, Thomas
[Steudel, Wolf-Ingo]
[Zang, Klaus D.]
Rahnenführer, Jörg
2007Journal Article
Applying Lasso regression to related cell types for gene network astimation
Universität des Saarlandes
Galata, Valentina2012Thesis - Bachelor thesis
Arby: Automatic protein structure prediction using profile-profile alignment and confidence measures
In: Bioinformatics [20], 2228-2235
[Öhsen von, Niklas]
Sommer, Ingolf
[Zimmer, Ralf]
Lengauer, Thomas
2004Journal Article
Arevir: A Secure Platform for Designing Personalized Antiretroviral Therapies Against HIV
In: Lecture Notes in Computer Science [4075], 185-194
Roomp, Kirsten
Beerenwinkel, Niko
Sing, Tobias
[Schülter, Eugen]
Büch, Joachim
[Sierra-Aragon, Saleta]
[Däumer, Martin]
[Hoffmann, Daniel]
[Kaiser, Rolf]
Lengauer, Thomas
[Selbig, Joachim]
2006Journal Article
Assessing Antibody Neutralization of HIV-1 as an Initial Step in the Search for gp160-based Immunogens
Universität des Saarlandes
Müller, Fabian2009Thesis - Masters thesis
Assessing the Conservation of Protein Function on Evolutionary Defined Patches
Universität des Saarlandes
Gwinner, Frederik2009Thesis - Masters thesis
Assessment of transcript reconstruction methods for RNA-seq
In: Nature Methods [10], 1177-84
[Steijger, T]
[Abril, JF]
[Engström,PG]
[Kokocinski, F]
[Abril, JF]
[Akerman, M]
[Alioto, T]
[Ambrosini, G]
[Antonarakis, SE]
[Behr, J]
[Bohnert, R]
[Bucher, P]
[Cloonan, N]
[Derrien, T]
[Djebali, S]
[Du, J]
[Dudoit, S]
[Engström, PG]
[Gerstein, M]
[Gingeras, TR]
[Gonzalez, D]
[Grimmond, SM]
[Habegger, L]
[Iseli, C]
[Jean, G]
[Kahles, A]
[Kokocinski, F]
[Lagarde, J]
[Leng, J]
[Lefebvre, G]
[Lewis, S]
[Mortazavi, A]
[Niermann, P]
[Rätsch, G]
[Reymond, A]
[Ribeca, P]
[Richard, H]
[Rougemont, J]
[Rozowsky, J]
[Sammeth, M]
[Sboner, A]
Schulz, Marcel Holger
[Searle, SM]
[Solorzano, ND]
[Solovyev, V]
[Stanke, M]
[Steijger, T]
[Stevenson, BJ]
[Stockinger, H]
[Valsesia, A]
[Weese, D]
[White, S]
[Wold, BJ]
[Wu, J]
[Wu, TD]
[Zeller, G]
[Zerbino, D]
[Zhang, MQ]
[Hubbard, TJ]
[Guigó, R]
[Harrow, J]
[Bertone, P]
2013Journal Article
Association Between HIV-1 Coreceptor Usage and Resistance to Some Broadly Neutralizing Antibodies
In: Proceedings of the AIDS Vaccine Conference 2013, A-1-A-208
Pfeifer, Nico
Lengauer, Thomas
2013Poster
Association between variants of PRDM1 and NDP52 and Crohn's disease, based on exome sequencing and functional studies
In: Gastroenterology [145], 339-347
[Ellinghaus, David]
[Zhang, Hu]
[Zeissig, Sebastian]
[Lipinski, Simone]
[Till, Andreas]
[Jiang, Tao]
[Stade, Björn]
[Bromberg, Yana]
[Ellinghaus, Eva]
[Keller, Andreas]
[Rivas, Manuel A.]
[Skieceviciene, Jurgita]
Doncheva, Nadezhda T.
[Liu, Xiao]
[Liu, Qing]
[Jiang, Fuman]
[Forster, Michael]
Mayr, Gabriele
Albrecht, Mario
[Häsler, Robert]
[Boehm, Bernhard O.]
[Goodall, Jane]
[Berzuini, Carlo R.]
[Lee, James]
[Andersen, Vibeke]
[Vogel, Ulla]
[Kupcinskas, Limas]
[Kayser, Manfred]
[Krawczak, Michael]
[Nikolaus, Susanna]
[Weersma, Rinse K.]
[Ponsioen, Cyriel Y.]
[Sans, Miquel]
[Wijmenga, Cisca]
[Strachan, David P.]
[McArdle, Wendy L.]
[Vermeire, Séverine]
[Rutgeerts, Paul]
[Sanderson, Jeremy D.]
[Mathew, Christopher G.]
[Vatn, Morten H.]
[Wang, Jun]
[Nöthen, Markus M.]
[Duerr, Richard H.]
[Büning, Carsten]
[Brand, Stephan]
[Glas, Jürgen]
[Winkelmann, Juliane]
[Illig, Thomas]
[Latiano, Anna]
[Annese, Vito]
[Halfvarson, Jonas]
[D'Amato, Mauro]
[Daly, Mark J.]
[Nothnagel, Michael]
[Karlsen, Tom H.]
[Subramani, Suresh]
[Rosenstiel, Philip]
[Schreiber, Stefan]
[Parkes, Miles]
[Franke, Andre]
2013Journal Article
Association of HCV-related mixed cryoglobulinemia with specific mutational patterns of the HCV E2 protein and CD81 expression on peripheral B lymphocytes
In: Blood [104], 1228-1229
[Hofmann, W.P.]
[Herrmann, E.]
[Kronenberger, B.]
Merkwirth, Christian
Welsch, Christoph
Lengauer, Thomas
[Zeuzem, S.]
[Sarrazin, C.]
2004Journal Article
Ataxin-2 and huntingtin interact with endophilin-A complexes to function in plastin-associated pathways
In: Human Molecular Genetics [14], 2893-2909
[Ralser, Markus]
[Nonhoff, Ute]
Albrecht, Mario
Lengauer, Thomas
[Wanker, Erich E.]
[Lehrach, Hans]
[Krobitsch, Sylvia]
2005Journal Article
Ausbildung im Bereich Bioinformatik
In: Ernst & Young Report Biotechnologie, Segmentreport Bioinformatik [1], 57-58
Lengauer, Thomas2002Journal Article
Automated clustering of ensembles of alternative models in protein structure databases
In: Protein Engineering Design and Selection [17], 537-543
Domingues, Francisco S.
Rahnenführer, Jörg
Lengauer, Thomas
2004Journal Article
Automated conformational analysis of macrocyclic ring systems
Universität des Saarlandes
Kaspar, Melanie2006Thesis - Masters thesis
Attachment IconAutomated Differential Analysis of Proteomes
Universität des Saarlandes
Schlicker, Andreas2004Thesis - Bachelor thesis
Automated generation of pharmacophore type constraints to improve FlexX docking
Universität des Saarlandes
Volkamer, Andrea2007Thesis - Masters thesis
Automated Grid Alignment for High-Throughput Analysis of Microarray Images (CIIST-02)
In: Proceedings of the 2002 International Conference on Imaging Science, Systems, and Technology, 161-167
[Bozinov, Daniel]
Rahnenführer, Jörg
[Burson, Cathy]
[Spiegelstein, Ofer]
[Arabnia, H. R.]
[Mun, Y.]
2002Proceedings Article
Automated Layout Generation and Wiring Area Estimation for 3D Electronic Modules
In: ASME Journal of Machanical Design [123], 330-336
[Schäfer, M.]
Lengauer, Thomas
2001Journal Article
Automatic detection of loss of heterozygosity in cancer
Universität des Saarlandes
König, Eva2012Thesis - Masters thesis
Automatic Generation of complementary descriptors with molecular graph networks
In: Journal of Chemical Information and Modeling [45], 1159-1168
Lengauer, Thomas
[Merkwirth, Christian]
2005Journal Article
Automatic Recombination Analysis Using Recoo and Mebitoo
Universität des Saarlandes
[Klingen, Thorsten]2012Thesis - Bachelor thesis
Bioinformatical approaches to ranking of anti-HIV combination therapies and planning of treatment schedules
Universität des Saarlandes
Altmann, André2010Thesis - PhD thesis
Bioinformatical Assistance of Selecting Anti-HIV Therapies: Where Do We Stand?
In: Intervirology [55], 108-112
Lengauer, Thomas2012Journal Article
Bioinformatics-assisted anti-HIV therapy
In: Nature Reviews Microbiology [4], 790-797
Lengauer, Thomas
Sing, Tobias
2006Journal Article
Bioinformatics - From Genomes to Therapies 1. The Building Blocks: Molecular Sequences and StructuresLengauer, Thomas2007Book
Bioinformatics - From Genomes to Therapies 2. Getting at the Inner Workings: Molecular InteractionsLengauer, Thomas2007Book
Bioinformatics - From Genomes to Therapies 3. The Holy Grail: Molecular FunctionLengauer, Thomas2007Book
Bioinformatics prediction of HIV coreceptor usage
In: Nature Biotechnology [25], 1407-1410
Lengauer, Thomas
Sander, Oliver
[Sierra, Saleta]
Thielen, Alexander
[Kaiser, Rolf]
2007Journal Article
Bioinformatik
In: Technologiefüher - Grundlagen, Anwendungen, Trends, 4
Lengauer, ThomasBullinger, H.J.2007Part of a Book
Bioinformatik an der Schwelle zur postgenomischen Ära
In: Was wissen wir, wenn wir das menschliche Genom kennen, 56-62
Lengauer, Thomas[Honnefelder, Ludger]
[Propping, Peter]
2001Part of a Book
Bioinformatikmethoden für die Optimierung antiviraler Kombinationstherapien
In: MPG Jahrbuch, 481-486
Beerenwinkel, Niko
[Däumer, Martin]
[Hoffmann, Daniel]
[Kaiser, Rolf]
[Selbig, Joachim]
Lengauer, Thomas
2003Part of a Book
Bioinformatik: Neue Strategien gegen Krebs
In: Deutsches Ärzteblatt PRAXiS [103], 10-11
Bock, Christoph2006Journal Article
Bioinformatische Unterstützung der Auswahl von HIV Therapien
In: Informatik Spektrum [32], 320-331
Lengauer, Thomas
Altmann, André
Thielen, Alexander
2009Journal Article
Bioinformatisches Data Mining erschließt neue Strategien gegen Krebs
In: Aktuelle Trends in der Softwareforschung, 91-99
Bock, Christoph
Halachev, Konstantin
Lengauer, Thomas
[Haasis, Klaus]
[Heinzl, Armin]
[Klumpp, Dieter]
2006Part of a Book
BiQ Analyzer HT: locus-specific analysis of DNA methylation by high-throughput bisulfite sequencing
In: Nucleic Acids Research [39], W551-W556
[Lutsik, Pavlo]
Feuerbach, Lars
[Arand, Julia]
Lengauer, Thomas
[Walter, Jörn]
Bock, Christoph
2011Journal Article
Attachment IconBiQ Analyzer: visualization and quality control for DNA methylation data from bisulfite sequencing
In: Bioinformatics [21], 4067-4068
Bock, Christoph
Lengauer, Thomas
[Reither, Sabine]
[Mikeska, Thomas]
[Paulsen, Martina]
[Walter, Jörn]
2005Journal Article
BLUEPRINT to decode the epigenetic signature written in blood
In: Nature Biotechnology [30], 224-226
[Adams, David]
[Altucci, Lucia]
[Antonarakis, Stylianos E]
[Ballesteros, Juan]
[Beck, Stephan]
[Bird, Adrian]
Bock, Christoph
[Boehm, Bernhard]
[Campo, Elias]
[Caricasole, Andrea]
[Dahl, Fredrik]
[Dermitzakis, Emmanouil T]
[Enver, Tariq]
[Esteller, Manel]
[Estivill, Xavier]
[Ferguson-Smith, Anne]
[Fitzgibbon, Jude]
[Flicek, Paul]
[Giehl, Claudia]
[Graf, Thomas]
[Grosveld, Frank]
[Guigó, Roderic]
[Gut, Ivo]
[Helin, Kristian]
[Jarvius, Jonas]
[Küppers, Ralf]
[Lehrach, Hans]
Lengauer, Thomas
[Lernmark, Åke]
[Leslie, David]
[Loeffler, Markus]
[Macintyre, Elizabeth]
[Mai, Antonello]
[Martens, Joost H A]
[Minucci, Saverio]
[Ouwehand, Willem H]
[Pelicci, Pier Giuseppe]
[Pendeville, Hèléne]
[Porse, Bo]
[Rakyan, Vardhman]
[Reik, Wolf]
[Schrappe, Martin]
[Schübeler, Dirk]
[Seifert, Martin]
[Siebert, Reiner]
[Simmons, David]
[Soranzo, Nicole]
[Spicuglia, Salvatore]
[Stratton, Michael]
[Stunnenberg, Hendrik G]
[Tanay, Amos]
[Torrents, David]
[Valencia, Alfonso]
[Vellenga, Edo]
[Vingron, Martin]
[Walter, Jörn]
[Willcocks, Spike]
2012Journal Article
BSIFlex: Binding Site Identification including protein flexibility
Universität des Saarlandes
Haid, Carla2007Thesis - Masters thesis
Calculating the statistical significance of changes in pathway activity from gene expression data
In: Statistical Applications in Genetics and Molecular Biology [3], Article 16
Rahnenführer, Jörg
Domingues, Francisco S.
Maydt, Jochen
Lengauer, Thomas
2004Electronic Journal Article
Cellular and Molecular Characterization of Early and Late Retinal Stem Cells/Progenitors: Differential Regulation of Proliferation and Context Dependent Role of Notch Signaling
In: Journal of Neurobiology [61], 359-376
[James, Jackson]
[Das, Ani V.]
Rahnenführer, Jörg
[Ahmad, Iqbal]
2004Journal Article
Centralization: A biologically sensible method for the normalization of gene expression data
In: Bioinformatics [17], 323S-331S
[Zien, Alexander]
[Aigner, T.]
[Zimmer, Ralf]
Lengauer, Thomas
2001Journal Article
Attachment IconCharacterization and structural analysis of novel mutations in human immunodeficiency virus type 1 reverse transcriptase involved in the regulation of restistance to nonnucleoside inhibitors
In: Journal of Virology [81], 11507-11519
[Ceccherini-Silberstein, Francesca]
[Svicher, Valentina]
Sing, Tobias
[Artese, Anna]
[Santoro, Maria Mercedes]
[Forbici, Federica]
[Bertoli, Ada]
[Alcaro, Stefano]
[Palamara, Guido]
[Monforte, Antonella d'Arminio]
[Balzarini, Jan]
[Antinori, Andrea]
Lengauer, Thomas
[Perno, Carlo Federico]
2007Journal Article
Characterization of HIV-1 Gag Subtype C
In: Abstract Book. 9th Workshop on HIV \& Hepatitis Treatment Strategies \& Antiviral Drug Resistance, 40-41
Pironti, Alejandro
Lengauer, Thomas
[Kaiser, Rolf]
[Schülter, Eugen]
[Verheyen, Jens]
2012Poster
Characterization of novel HIV Drug Resistance Mutations using clustering, multidimensional scaling and SVM-based feature ranking
In: Knowledge Discovery in Databases: PKDD 2005., 285-296
Sing, Tobias
[Svicher, Valentina]
Beerenwinkel, Niko
[Ceccherini-Silberstein, Francesca]
[Däumer, Martin]
[Kaiser, Rolf]
[Walter, Hauke]
[Korn, Klaus]
[Hoffmann, Daniel]
[Oette, Mark]
[Rockstroh, Jürgen K.]
Fätkenheuer, Gerd
[Perno, Carlo-Federico]
Lengauer, Thomas
[Jorge, A]
[Torgo, L]
[Brazdil, P]
[Camacho, R]
[Gama, J]
2005Proceedings Article
Characterization of resistance to the protease inhibitor boceprevir in hepatitis C virus-infected patients.
In: Hepatology [50], 1709-1718
[Susser, Simone]
Welsch, Christoph
[Wang, Yalan]
[Zettler, Markus]
Domingues, Francisco S.
[Karey, Ursula]
[Hughes, Eric]
[Ralston, Robert]
[Tong, Xiao]
[Herrmann, Eva]
[Zeuzem, Stefan]
[Sarrazin, Christoph]
2009Journal Article
Characterization, classification and alignment of protein-protein interfaces
Universität des Saarlandes
Zhu, Hongbo2010Thesis - PhD thesis
Charting a dynamic DNA methylation landscape of the human genome
In: Nature [500], 477–481
[Ziller, Michael J.]
[Gu, Hongcang]
Müller, Fabian
[Donaghey, Julie]
[Tsai, Linus T.-Y.]
[Kohlbacher, Oliver]
[De Jager, Philip L.]
[Rosen, Evan D.]
[Bennett, David A.]
[Bernstein, Bradley E.]
[Gnirke, Andreas]
[Meissner, Alexander]
2013Journal Article
Chasing the AIDS Virus
In: Communications of the ACM [53], 66-74
Lengauer, Thomas
Altmann, André
Thielen, Alexander
[Kaiser, Rolf]
2010Journal Article
Circadian transcription in liver
In: Biosystems [102], 61-69
Bozek, Katarzyna
[Rosahl, A. L.]
[Gaub, S.]
[Lorenzen, S.]
[Herzel, H.]
2010Journal Article
Classification with correlated features: unreliability of feature ranking and solutions
In: Bioinformatics [27], 1986-1994
Tolosi, Laura
Lengauer, Thomas
2011Journal Article
Clinical relevance of the 2'-5'-oligoadenylate synthetase/RNase L system for treatment response in chronic hepatitis C
In: Journal of Hepatology [50], 49-58
[Mihm, Ulrike]
[Ackermann, Oliver]
Welsch, Christoph
[Herrmann, Eva]
[Hofmann, Wolf Peter]
[Grigorian, Natalia]
[Welker, Martin Walter]
Lengauer, Thomas
[Zeuzem, Stefan]
[Sarrazin, Christoph]
2009Journal Article
Clinical significance of in vitro replication-enhancing mutations of the hepatitis C virus (HCV) replicon in patients with chronic HCV infection
In: The Journal of Infectious Diseases [192], 1710-1719
[Sarrazin, Christoph]
[Mihm, Ulrike]
[Herrmann, Eva]
[Welsch, Christoph]
Albrecht, Mario
[Sarrazin, Ulrike]
[Traver, Stella]
Lengauer, Thomas
[Zeuzem, Stefan]
2005Journal Article
Cloudbasierte Analyse von viralen Sequenzdaten der neuesten Generation
Universität des Saarlandes
Zeidler, Michael2012Thesis - Bachelor thesis
Clustering algorithms and other exploratory methods for microarray data analysis
In: Methods of Information in Medicine [44], 444-448
Rahnenführer, Jörg2005Journal Article
Clustering epigenetic data using a Dirichlet process prior
Universität des Saarlandes
Bader, Mathias2012Thesis - Masters thesis
clusterMaker: A Multi-algorithm Clustering Plugin for Cytoscape
In: BMC Bioinformatics [12], 436,1-436,14
[Morris, John H.]
[Apeltsin, Leonard]
[Newman, Aaron M.]
Baumbach, Jan
[Wittkop, Tobias]
[Su, Gang]
[Bader, Gary D.]
[Ferrin, Thomas E.]
2011Journal Article
Co-clustering of biological networks and gene expression data
In: Proceedings of the Tenth Conference on Intelligent Systems for Molecular Biology (ISMB 2002), 145-154
[Hanisch, Daniel]
[Zien, Alexander]
[Zimmer, Ralf]
Lengauer, Thomas
2002Proceedings Article
Color blindness
In: Nature Methods [7], 775
Albrecht, Mario2010Journal Article
Combinatorial Optimization Techniques for Three-Dimensional Arrangement Problems
In: Mathematics - Key Technology for the Future, 63-73
Lengauer, Thomas
[Schäfer, M.]
[Jäger, Willi]
[Krebs, Hans-Joachim]
2003Part of a Book
Combined similarity and QSPR virtual screening for guest molecules of $\beta$-cyclodextrin
In: New Journal of Chemistry [31], 1941-1949
Steffen, Andreas
[Karasz, Maximilian]
[Thiele, Carolin]
Lengauer, Thomas
Kämper, Andreas
[Wenz, Gerhard]
[Apostolakis, Joannis]
2007Journal Article
Combining protein structure prediction with experiments and functional information
Universität des Saarlandes
Albrecht, Mario2006Thesis - PhD thesis
Common genetic variation in ABCA1 is associated with altered lipoprotein levels and a modified risk for coronary artery disease
In: Circulation [103], 1198-205
[Clee, Susanne M.]
[Zwinderman, A.H.]
[Engert, J.C.]
[Zwarts, K.Y.]
[Molhuizen, H.O.]
Roomp, Kirsten
[Jukema, J.W.]
[van Wijland, M]
[van Dam, M]
[Hudson, T.J.]
[Brooks-Wilson, A]
[Genest, Jacques Jr]
[Kastelein, J.J.P.]
[Hayden, Michael R.]
2001Journal Article
Attachment IconComparative Analysis of Protein Structure Alignments
In: BMC Structural Biology [7], 1
Mayr, Gabriele
Domingues, Francisco S.
[Lackner, Peter]
2007Journal Article
Comparative Epigenomiocs - Towards Ancestral Germline Methylome Reconstruction
In: Abstracts of papers presented at the 2010 meeting on The Biology of genomes, 87
Feuerbach, Lars
Lyngsoe, Rune
Lengauer, Thomas
[Hein, Jotun]
2010Poster
Comparative genome-wide DNA methylation analysis of colorectal tumor and matched human tissue
In: Epigenetics [7], 1355-1367
[Simmer, F.]
[Brinkmann, A.B.]
Assenov, Yassen
[Matarese, F.]
[Kaan, A.]
Lengauer, Thomas
Bock, Christoph
[Colantuoni, V.]
[Altucci, L.]
[Stunnenberg, H.G.]
2013Journal Article
Comparative genome-wide DNA methylation analysis of colorectal tumor and matched normal tissues
In: Epigenetics [7], 1355-1367
[Simmer, Femke]
[Brinkman, Arie B.]
Assenov, Yassen
[Matarese, Filomena]
[Kaan, Anita]
[Sabatino, Lina]
[Villanueva, Alberto]
[Huertas, Dori]
[Esteller, Manel]
Lengauer, Thomas
Bock, Christoph
[Colantuoni, Vittorio]
[Altucci, Lucia]
[Stunnenberg, Henk G.]
2012Journal Article
Comparative Genomics of Klebsiella pneumoniae Strains with Different Antibiotic Resistance Profiles
In: Antimicrobial Agents and Chemotherapy [55], 4267-4276
[Kumar, Vinod]
Sun, Peng
[Vamathevan, Jessica]
[Li, Yong]
[Ingraham, Karen]
[Palmer, Leslie]
[Huang, Jianzhong]
[Brown, James R.]
2011Journal Article
Comparative quality analyses for hybrid clustering of microarray images
In: Proceedings of the Sventh Annual International Conference on Computational Biology, -
Rahnenführer, Jörg
Bozinov, Daniel
2003Poster
Comparison of Classifier Fusion Methods for Predicting Response to Anti HIV-1 Therapy
In: PLoS ONE [3], e3470
Altmann, Andre
[Rosen-Zvi, Michal]
[Prosperi, Mattia]
[Aharoni, Ehud]
[Neuvirth, Hani]
[Sönnerborg, Anders]
[Schülter, Eugen]
Büch, Joachim
[Struck, Daniel]
[Peres, Yardena]
[Incardona, Francesca]
[Kaiser, Rolf]
[Zazzi, Maurizio]
Lengauer, Thomas
2008Journal Article
Comparison of Envelope 2 CD81 binding regions in PBMC-derived versus serum-derived hepatitis C virus isolates: higher conservation of CD81 region 2 in PBMC isolates
In: Journal of Viral Hepatitis [18], 181-192
[Welker, M.-W.]
Welsch, Christoph
[Ochs, D.]
[Hofmann, W. P.]
[Herrmann, E.]
[Piiper, A.]
[Hartmann, R. W.]
[Zeuzem, S.]
[Sarrazin, C.]
[Kronenberger, Bernd]
2011Journal Article
Comparison of methods for discovering genomic aberrations relevant for cancer
Universität des Saarlandes
Ivanova, Violeta2011Thesis - Masters thesis
Comparison of sequencing-based methods to profile DNA methylation and identification of monoallelic epigenetic modifications
In: Nature Biotechnology [28], 1097-1105
[Harris, R. Alan]
[Wang, Ting]
[Coarfa, Cristian]
[Nagarajan, Raman P.]
[Hong, Chibo]
[Downey, Sara L.]
[Johnson, Brett E.]
[Fouse, Shaun D.]
[Delaney, Allen]
[Zhao, Yongjun]
[Olshen, Adam]
[Ballinger, Tracy]
[Zhou, Xin]
[Forsberg, Kevin J.]
[Gu, Junchen]
[Echipare, Lorigail]
[O'Geen, Heriette]
[Lister, Ryan]
[Pelizzola, Mattia]
[Xi, Yuanxin]
[Epstein, Charles B.]
[Bernstein, Bradley E.]
[Hawkins, R. David]
[Ren, Bing]
[Chung, Wen-Yu]
[Gu, Hongcang]
Bock, Christoph
[Gnirke, Andreas]
[Zhang, Michael Q.]
[Haussler, David]
[Ecker, Joseph R.]
[Li, Wei]
[Farnham, Peggy J.]
[Waterland, Robert a.]
[Meissner, Alexander]
[Marra, Marco A.]
[Hirst, Martin]
[Milosavljevic, Aleksandar]
[Costello, Joseph F.]
2010Journal Article
Compensatory mutations at the HIV cleavage sites p7/p1 and p1/p6-gag in therapy-naive and therapy-experienced patients
In: Antiviral Therapy [11], 879-887
[Verheyen, Jens]
[Litau, Elena]
Sing, Tobias
[Däumer, Martin]
[Balduin, Melanie]
[Oette, Mark]
[Fätkenheuer, Gerd]
[Rockstroh, Jürgen K.]
[Schuldenzucker, Ulrike]
[Hoffmann, Daniel]
[Pfister, Herbert]
[Kaiser, Rolf]
2006Journal Article
Comprehensive cluster analysis with Transitivity Clustering
In: Nature Protocols [6], 285-295
[Wittkop, Tobias]
Emig, Dorothea
[Truss, Anke]
Albrecht, Mario
[Böcker, Sebastian]
Baumbach, Jan
2011Journal Article
Computational analysis of covariation and interactions between HIV-1 reverse transcriptase and Integrase
In: Reviews in Antiviral Therapy, 113-114
Sander, Oliver
Altmann, Andre
Lengauer, Thomas
2008Poster
Computational Analysis of genomic HPV data
Universität des Saarlandes
Ebert, Peter2009Thesis - Bachelor thesis
Computational Analysis of HIV Drug resistance DataBeerenwinkel, Niko2004Book
Attachment IconComputational Analysis of HIV Drug Resistance Data
Universität des Saarlandes
Beerenwinkel, Niko2003Thesis - PhD thesis
Computational analysis of human protein interaction networks
In: Proteomics [7], 2541-2552
Ramírez, Fidel
Schlicker, Andreas
Assenov, Yassen
Lengauer, Thomas
Albrecht, Mario
2007Journal Article
Computational Approaches in Supramolecular Chemistry with a special Focus on Virtual Screening
Universität des Saarlandes
Steffen, Andreas2008Thesis - PhD thesis
Computational Biology
In: Encyclopedia of Molecular Cell Biology and Molecular Medicine, 1-71
Lengauer, Thomas
Albrecht, Mario
Domingues, Francisco S.
[Meyers, Robert A.]2012Part of a Book
Attachment IconComputational epigenetics
In: Bioinformatics [24], 1-10
Bock, Christoph
Lengauer, Thomas
2008Journal Article
Computational Epigenetics - Bioinformatic methods for epigenome prediction, DNA methylation mapping and cancer epigenetics
Universität des Saarlandes
Bock, Christoph2008Thesis - PhD thesis
Attachment IconComputational Epigenetics: Bioinformatik für neue Wege in der Krebsforschung
In: Jahrbuch 2007, 271-277
Bock, Christoph
Lengauer, Thomas
2007Part of a Book
Computational Identification of Novel Amino-Acid Interactions in HIV Gag via Correlated Evolution
In: PLoS ONE [7], e42468,1-e42468,5
Kalinina, Olga V.
[Oberwinkler, Heike]
[Glass, Bärbel]
[Kräusslich, Hans-Georg]
[Russell, Robert B.]
[Briggs, John A. G.]
2012Electronic Journal Article
Computational Methods For Metabolite Screening
In: Proceedings of the 12th International Conference on Intelligent Systems for Molecular Biology + 3rd European Conference on Computational Biology (ISMB/ECCB 2004), 1
Talwar, Priti
Lengauer, Thomas
Rahnenführer, Jörg
[Velagapudi, VR]
[Wittmann, Christoph]
[Heinzle, Elmar]
2004Poster
Computational Methods For Metabolite Screening
In: Proceedings of the 5th International Conference on Systems Biology (ICSB 2004), 1
Talwar, Priti
Lengauer, Thomas
Rahnenführer, Jörg
[Velagapudi, VR]
[Wittmann, Christoph]
[Heinzle, Elmar]
2004Poster
Attachment IconComputational Methods for Metabolomic Data Analysis of Ion Mobility Spectrometry Data - Reviewing the State of the Art
In: Metabolites [2], 733-755
Hauschild, Anne-Christin
[Schneider, Till]
Pauling, Josch
[Rupp, Kathrin]
[Jang, Mi]
[Baumbach, Jörg Ingo]
Baumbach, Jan
2012Electronic Journal Article
Computational Methods for Protein Function Prediction using Metabolomics Data
In: Proceedings of International Workshop on Systems Biology 2005, 1
Talwar, Priti
Lengauer, Thomas
Rahnenführer, Jörg
[Wittmann, Christoph]
[Velagapudi, VR]
[Heinzle, Elmar]
2005Poster
Computational methods for the design of effective therapies against drug resistant HIV strains
In: Bioinformatics [21], 3943-3950
[Beerenwinkel, Niko]
Sing, Tobias
Lengauer, Thomas
Rahnenführer, Jörg
Roomp, Kirsten
Savenkov, Igor
[Fischer, Roman]
[Hoffmann, Daniel]
[Selbig, Joachim]
[Korn, Klaus]
[Walter, Hauke]
[Berg, Thomas]
[Braun, Patrick]
[Fätkenheuer, Gerd]
[Oette, Mark]
[Rockstroh, Jürgen]
[Kupfer, Bernd]
[Kaiser, Rolf]
[Däumer, Martin]
2005Journal Article
Computational Methods for the Investigation of Protein-Ligand Interactions
Universität des Saarlandes
Antes, Iris2009Thesis - Habilitation thesis
Computational prediction of MHC-peptide interactions
Universität des Saarlandes
Siu, Shirley Weng-In2005Thesis - Masters thesis
Computational recognition of potassium channel sequences
In: Bioinformatics [13], 1562-1568
[Heil, Burkhard]
[Ludwig, Jost]
[Lichtenberg-Fraté, Hella]
Lengauer, Thomas
2006Journal Article
Computerjagd auf das AIDSVIRUS
In: Spektrum der Wissenschaft [08], 62-67
Lengauer, Thomas
[Kaiser, Rolf]
2009Journal Article
Computermodelle in der Wissenschaft - zwischen Analyse, Vorhersage und SuggestionLengauer, Thomas2011Book
Computing the genetic barrier
In: XII International HIV Drug resistance Workshop, S125-S125
Beerenwinkel, Niko
Sing, Tobias
[Däumer, Martin]
[Kaiser, Rolf]
Lengauer, Thomas
[Boucher, Charles]
[Mellors, John]
[Larder, Brendan]
[Richman, Douglas]
2004Proceedings Article
Computing topological parameters of biological networks
In: Bioinformatics [24], 282-284
Assenov, Yassen
Ramírez, Fidel
Schelhorn, Sven-Eric
Lengauer, Thomas
Albrecht, Mario
2008Journal Article
Confidence measures for protein fold recognition
In: Bioinformatics [18], 802-812
Sommer, Ingolf
[Zien, Alexander]
[Öhsen von, Niklas]
[Zimmer, Ralf]
Lengauer, Thomas
2002Journal Article
Confirmation of human protein interaction data by human expression data
In: BMC Bioinformatics [6], 1-11
Hahn, Andreas
Rahnenführer, Jörg
Talwar, Priti
Lengauer, Thomas
2005Journal Article
Conformational analysis of alternative protein structures
In: Bioinformatics [23], 3131-3138
Domingues, Francisco S.
[Rahnenführer, Jörg]
Lengauer, Thomas
2007Journal Article
Attachment IconConformational Analysis of Macrocyclic Ring Systems
Universität des Saarlandes
Kaspar, Melanie2005Thesis - Bachelor thesis
Correlation nonstructural (NS)4B amino acid variations with initial viral kinetics during interferon-alpha-based therapy in HCV-1b-infected patients
In: Journal of Viral Hepatitis [14], 338-349
[Welker, Martin W.]
[Hofmann, Wolf-Peter]
[Welsch, Christoph]
[von Wagner, Michael]
[Herrmann, Eva]
[Lengauer, Thomas]
[Zeuzem, Stefan]
[Sarrazin, Christoph]
2007Journal Article
CoryneRegNet 6.0 - Updated database content, new analysis methods and novel features focusing on community demands
In: Nucleic Acids Research [40], D610-D614
Pauling, Josch
Röttger, Richard
[Tauch, Andreas]
[Azevedo, Vasco]
Baumbach, Jan
2012Journal Article
Cost-effective screening for differentially expressed genes in microarray experiments based on normal mixtures
In: Austrian Journal of Statistics [32], 225-238
Rahnenführer, Jörg
[Futschik, Andreas]
2003Journal Article
Attachment IconCpG Island Mapping by Epigenome Prediction
In: PLoS Computational Biology [3], 1055-1070
Bock, Christoph
[Walter, Jörn]
[Paulsen, Martina]
Lengauer, Thomas
2007Journal Article
Attachment IconCpG Island Methylation in Human Lymphocytes Is Highly Correlated with DNA Sequence, Repeats, and Predicted DNA Structure
In: PLoS Genetics [2], 0243-0252
Bock, Christoph
[Paulsen, Martina]
[Tierling, Sascha]
[Mikeska, Thomas]
Lengauer, Thomas
[Walter, Jörn]
2006Electronic Journal Article
Current breathomics – A review on data pre-processing techniques and machine learning in metabolomics breath analysis[Smolinska, Agnieszka]
Hauschild, Anne-Christin
[Fijten, Rianne]
[Dallinga, Jan]
Baumbach, Jan
[van Schooten, Frederik]
2014Unpublished/Draft
Current V3 genotyping algorithms are inadequate for predicting X4 co-receptor usage in clinical isolates
In: AIDS [21], F19-F26
[Low, Andrew J.]
[Dong, Winnie]
[Chan, Dennison]
Sing, Tobias
[Swanstrom, Ronald]
[Jensen, Mark]
[Pillai, Satish]
[Good, Benjamin]
[Harrigan, P. Richard]
2007Journal Article
Das Arevir-Projekt : neue Wege zur Optimierung von Anti-HIV-Therapien
In: Resistenz in der HIV-Therapie : Diagnostik und Management, 94-98
Beerenwinkel, Niko[Oette, Mark]
[Kaiser, Rolf]
[Häussinger, Dieter]
2004Part of a Book
DASMIweb: online integration, analysis and assessment of distributed protein interaction data
In: Nucleic Acids Research [37], W122-W128
Blankenburg, Hagen
Ramírez, Fidel
Büch, Joachim
Albrecht, Mario
2009Electronic Journal Article
DASMI: exchanging, annotating and assessing molecular interaction data
In: Bioinformatics [25], 1321-1328
Blankenburg, Hagen
[Finn, Robert D.]
[Prlić, Andreas]
[Jenkinson, Andrew M.]
Ramírez, Fidel
Emig, Dorothea
Schelhorn, Sven-Eric
Büch, Joachim
Lengauer, Thomas
Albrecht, Mario
2009Journal Article
Attachment IconDealing with sparse data in predicting outcomes of HIV combination therapies
In: Bioinformatics [26], 2085-2092
Bogojeska, Jasmina
[Bickel, Steffen]
Altmann, André
Lengauer, Thomas
2010Journal Article
Decomposing Protein Networks Into
Domain-Domain Interactions
Eberhard Karls University Tübingen
Huthmacher, Carola2006Thesis - other
Decomposing protein networks into domain-domain interactions
In: Bioinformatics [21], ii220-ii221
Albrecht, Mario
Huthmacher, Carola
[Tosatto, Silvio C.E.]
Lengauer, Thomas
2005Journal Article
Decreased HIV diversity after allogeneic stem cell transplantation of an HIV-1 infected patient: a case report.
In: Virology Journal [7], 55,1-55,9
[Kamp, Christel]
[Wolf, Timo]
[Bravo, Ignacio G]
[Kraus, Benjamin]
[Krause, Birgit]
[Neumann, Britta]
[Winskowsky, Gudrun]
Thielen, Alexander
[Werner, Albrecht]
[Schnierle, Barbara S]
2010Electronic Journal Article
Deep sequencing reveals mutagenic effects of ribavirin during monotherapy of HCV genotype 1-infected patients
In: Journal of Virology [87], 6172-6181
[Dietz, J.]
Schelhorn, Sven-Eric
[Fitting, D.]
[Mihm, U.]
[Susser, S.]
[Welker, M.-W.]
[Füller, C.]
[Däumer, M.]
[Teuber, G.]
[Wedemeyer, H.]
[Berg, T.]
Lengauer, Thomas
[Z., Stefan]
[Herrmann, E.]
[Sarrazin, C.]
2013Journal Article
Deep Sequencing to Infer HIV-1 Co-Receptor Usage: Application to Three Clinical Trials of Maraviroc in Treatment-Experienced Patients
In: The Journal of Infectious Diseases [203], 237-245
[Swenson, Luke C.]
[Mo, Theresa]
[Dong, Winnie W. Y.]
[Zhong, Xiaoyin]
[Woods, Conan K.]
[Jensen, Mark A.]
Thielen, Alexander
[Chapman, Douglass]
[Lewis, Marilyn]
[James, Ian]
[Heera, Jayvant]
[Valdez, Hernan]
[Harrigan, P. Richard]
2011Journal Article
Deep V3 sequencing for HIV type 1 tropism in treatment-naive patients: a reanalysis of the MERIT trial of maraviroc.
In: Clinical Infectious Diseases [53], 732-742
[Swenson, Luke C]
[Mo, Theresa]
[Dong, Winnie WY]
[Zhong, Xiaoyin]
[Woods, Conan K]
Thielen, Alexander
[Jensen, Mark A]
[Knapp, David JHF]
[Chapman, Douglass]
[Lewis, Marilyn]
[James, Ian]
[Heera, Jayvant]
[Valdez, Hernan]
[Harrigan, P Richard]
2011Journal Article
Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis
In: Nature Genetics [45], 670-677
[Liu, Jimmy Z.]
[Hov, Johannes Roksund]
[Folseraas, Trine]
[Ellinghaus, Eva]
[Rushbrook, Simon M.]
Doncheva, Nadezhda T.
[Andreassen, Ole A.]
[Weersma, Rinse K.]
[Weismuller, Tobias J.]
[Eksteen, Bertus]
[Invernizzi, Pietro]
[Hirschfield, Gideon M.]
[Gotthardt, Daniel Nils]
[Pares, Albert]
[Ellinghaus, David]
[Shah, Tejas]
[Juran, Brian D.]
[Milkiewicz, Piotr]
[Rust, Christian]
[Schramm, Christoph]
[Muller, Tobias]
[Srivastava, Brijesh]
[Dalekos, Georgios]
[Nothen, Markus M.]
[Herms, Stefan]
[Winkelmann, Juliane]
[Mitrovic, Mitja]
[Braun, Felix]
[Ponsioen, Cyriel Y.]
[Croucher, Peter J. P.]
[Sterneck, Martina]
[Teufel, Andreas]
[Mason, Andrew L.]
[Saarela, Janna]
[Leppa, Virpi]
[Dorfman, Ruslan]
[Alvaro, Domenico]
[Floreani, Annarosa]
[Onengut-Gumuscu, Suna]
[Rich, Stephen S.]
[Thompson, Wesley K.]
[Schork, Andrew J.]
[Naess, Sigrid]
[Thomsen, Ingo]
Mayr, Gabriele
[Konig, Inke R.]
[Hveem, Kristian]
[Cleynen, Isabelle]
[Gutierrez-Achury, Javier]
[Ricano-Ponce, Isis]
[van Heel, David]
[Bjornsson, Einar]
[Sandford, Richard N.]
[Durie, Peter R.]
[Melum, Espen]
[Vatn, Morten H.]
[Silverberg, Mark S.]
[Duerr, Richard H.]
[Padyukov, Leonid]
[Brand, Stephan]
[Sans, Miquel]
[Annese, Vito]
[Achkar, Jean-Paul]
[Boberg, Kirsten Muri]
[Marschall, Hanns-Ulrich]
[Chazouilleres, Olivier]
[Bowlus, Christopher L.]
[Wijmenga, Cisca]
[Schrumpf, Erik]
[Vermeire, Severine]
Albrecht, Mario
[The UK-PSCSC Consortium,]
[The International IBD Genetics Consortium,]
[Rioux, John D.]
[Alexander, Graeme]
[Bergquist, Annika]
[Cho, Judy]
[Schreiber, Stefan]
[Manns, Michael P.]
[Farkkila, Martti]
[Dale, Anders M.]
[Chapman, Roger W.]
[Lazaridis, Konstantinos N.]
[The International PSC Study Group,]
[Franke, Andre]
[Anderson, Carl A.]
[Karlsen, Tom H.]
2013Journal Article
Density Parameter Estimation for Finding Clusters of Homologous Proteins - Tracing Actinobacterial Pathogenicity Life Styles
In: Bioinformatics [29], 215-222
[Röttger, Richard]
Kalaghatgi, Prabhav
[Sun, Peng]
[de Castro Soares, Siomar]
[Azevedo, Vasco]
[Wittkop, Tobias]
[Baumbach, Jan]
2013Journal Article
Derivation of a scoring function for crystal structure prediction
In: Acta Crystallographica [A57], 442-450
[Apostolakis, Joannis]
[Hofmann, D.]
Lengauer, Thomas
2001Journal Article
Detection of Novel Amplicons in Prostate Cancer by Comprehensive Genomic Profiling of Prostate Cancer Cell Lines Using Oligonucleotide-Based ArrayCGH
In: PLoS ONE [2], e769
[Kamradt, Jörn]
[Jung, Volker]
[Wahrheit, Kerstin]
Tolosi, Laura
Rahnenführer, Jörg
[Schilling, Martin]
[Walker, Robert]
[Davis, Sean]
[Stöckle, Michael]
[Meltzer, Paul]
[Wullich, Bernd]
2007Electronic Journal Article
Determination of clinically relevant cutoffs for HIV-1 phenotypic resistance estimates through a combined analysis of clinical trial and cohort data
In: Abstract Book. 8th European Drug Resistance Workshop, 46
Altmann, Andre
Pironti, Alejandro
Perner, Juliane
Büch, Joachim
Lengauer, Thomas
[Schapiro, Jonathan]
[Boucher, Charles]
2010Poster
Determination of HIV-1 co-receptor usage in German patients – comparison of genotypic methods with the TROFILE® phenotypic assay
In: Abstracts of the Ninth International Congress on Drug Therapy in HIV Infection, 123
[Obermeier, Martin]
[Berg, Thomas]
[Sichtig, Nadine]
[Braun, Patrick]
[Däumer, Martin]
[Walter, Hauke]
[Noah, Christian]
[Wolf, Eva]
[Müller, Harm]
[Stürmer, Martin]
Thielen, Alexander
[Kaiser, Rolf]
2008Poster
Determination of HIV-1 coreceptor usage in German patients - comparison of genotypic methods with the TROFILE phenotypic assay
In: Antiviral Therapy, A112
[Obermeier, Martin]
[Sichtig, Nadine]
[Braun, Patrick]
[Däumer, Martin]
[Walter, Hauke]
[Noah, Christian]
[Wolf, Eva]
[Müller, Harm]
[Stürmer, Martin]
[Kaiser, Rolf]
Thielen, Alexander
2008Poster
Attachment IconDetermining human immunodeficiency virus coreceptor use in a clinical setting: Degree of correlation between two phenotypic assays and a bioinformatic model
In: Journal of Clinical Microbiology [45], 279-284
[Skrabal, Katharina]
[Low, Andrew J.]
[Dong, Winnie]
Sing, Tobias
[Cheung, Peter K.]
[Mammano, Fabrizio]
[Harrigan, P. Richard]
2007Journal Article
Development of a
Smith-Waterman-Like Multi-Aspect
Alignment Tool
Universität des Saarlandes
Frings, Oliver2006Thesis - Bachelor thesis
Development of a fast
geometry-based screening
compound prefiltering technique
Universität des Saarlandes
Pfeifer, Susanne2006Thesis - Bachelor thesis
Development of a new tool for predicting the structure of host-guest complexes
In: Proceedings of the 2nd Summer School Medicinal Chemistry Regensburg 2004, 83
Steffen, Andreas
Kämper, Andreas
Lengauer, Thomas
2004Poster
Development of Computational Methods for Analysis of Metabolic Profiling Data
In: Proceedings of International Conference on Systems Biology (ICSB 2006), Japan, 42-42
Talwar, Priti
Lengauer, Thomas
[Wittmann, Christoph]
[Velagapudi, V. R.]
[Heinzle, Elmar]
2006Proceedings Article
Development of Computational Methods for Metabolic Network Analysis based on Metabolomics Data
Universität des Saarlandes
Talwar, Priti2008Thesis - PhD thesis
DIDO: a disease-determinants ontology from web sources
In: Proceedings of the 20th International Conference on World Wide Web (WWW 2011), 237-240
Nebot, Victoria
Ye, Min
Albrecht, Mario
Eom, Jae-Hong
Weikum, Gerhard
2011Proceedings Article
Dimerization of the hepatitis C virus nonstructural protein 4B depends on the integrity of an aminoterminal basic leucine zipper
In: Protein Science [19], 1327-1336
[Welker, Martin-Walter]
[Welsch, Christoph]
[Meyer, Aline]
Antes, Iris
Albrecht, Mario
[Forestier, Nicole]
[Kronenberger, Bernd]
Lengauer, Thomas
[Piiper, Albrecht]
[Zeuzem, Stefan]
[Sarrazin, Christoph]
2010Journal Article
Disease-associated variants in PYPAF1 and NOD2 result in similar alterations of conserved sequence
In: Bioinformatics [19], 2171-2175
Albrecht, Mario
Lengauer, Thomas
[Schreiber, Stefan]
2003Journal Article
Disease gene prioritization by combining network information and functional knowledge
Universität des Saarlandes
Kacprowski, Tim2011Thesis - Masters thesis
Dissection of the inflammatory bowel disease transcriptome using genome-wide cDNA microarrays identifies novel candidate disease genes
In: PLoS Medicine [2], 771-787
[Costello, Christine M.]
[Mah, Nancy]
[Häsler, Robert]
[Rosenstiel, Philip]
[Waetzig, Georg H.]
Hahn, Andreas
[Lu, Tim]
[Gurbuz, Yesim]
[Nikolaus, Susanna]
Albrecht, Mario
[Hampe, Jochen]
[Lucius, Ralph]
[Klöppel, Günther]
[Eickhoff, Holger]
[Lehrach, Hans]
Lengauer, Thomas
[Schreiber, Stefan]
2005Journal Article
Diversity and complexity of HIV-1drug resistance: A bioinformatics approach to predicting phenotype from genotype
In: Proceedings of the National Academy of Sciences [99], 8271-8276
Beerenwinkel, Niko
[Schmidt, Barbara]
[Walter, Hauke]
[Kaiser, Rolf]
Lengauer, Thomas
[Hoffmann, Daniel]
[Korn, Klaus]
[Selbig, Joachim]
2002Journal Article
Diversity and functional plasticity of eukaryotic selenoproteins: Identification and characterization of the SelJ family
In: Proceedings of the National Academy of Sciences [102], 16188-16193
[Castellano, Sergi]
[Lobanov, Alexey V.]
[Chapple, Charles]
[Novoselov, Sergey V.]
Albrecht, Mario
[Hua, Deame]
[Lescure, Alain]
Lengauer, Thomas
[Krol, Alain]
[Gladyshev, Vadim N.]
[Guigó, Roderic]
2005Journal Article
Attachment IconDNA methylation analysis of chromosome 21 gene promoters at single base pair and single allele resolution
In: PLoS Genetics [5], e1000438:1-e1000438:15
[Zhang, Yingying]
[Rohde, Christian]
[Tierling, Sascha]
[Jurkowski, Tomasz P.]
Bock, Christoph
[Santacruz, Diana]
[Ragozin, Sergey]
[Reinhardt, Richard]
[Groth, Marco]
[Walter, Jörn]
[Jeltsch, Albert]
2009Electronic Journal Article
DNA methylation biomarkers in cancer: Progress towards clinical implementation
In: Expert Reviews of Molecular Diagnostics [12], 473-487
[Mikeska, Thomas]
Bock, Christoph
[Do, Hongdo]
[Dobrovic, Alexander]
2012Journal Article
DNA Methylation Patterns Facilitate the Identification of Transcription Start Sites: A Brain-specofoc Study
In: PLOSONE [8], xx
[Bhadra, T.]
[Battacharya, M.]
[Feuerbach, L.]
Lengauer, Thomas
Bandyopadhyay, S.
2013Journal Article
Docking Analysis and Resistance Evaluation of Clinically Relevant Mutations Associated with the HIV-1 Nonnucleoside Reverse Transcriptase Inhibitors Nevirapine, Efavirenz and Etravirine
In: ChemMedChem [6], 2203-2213
[Alcaro, Stefano]
[Alteri, Claudia]
[Artese, Anna]
[Ceccherini-Silberstein, Francesca]
[Costa, Giosuè]
[Ortuso, Francesco]
[Forbici, Federica]
[Santoro, Maria Mercedes]
[Parrotta, Lucia]
[Flandre, Philippe]
[Descamps, Diane]
[Calvez, Vincent]
[Marcelin, Anne-Genevieve]
[Perno, Carlo Federico]
Sing, Tobias
[Svicher, Valentina]
2011Journal Article
Docking and scoring with alternative side-chain conformations
In: Proteins: Structure, Function, and Bioinformatics [74], 712-726
Hartmann, Christoph
Antes, Iris
Lengauer, Thomas
2009Journal Article
Docking into the homology models of CYP11B1 and CYP11B2
In: Proceedings of the German Conference on Bioinformatics 2003, 13
Antes, Iris
Lengauer, Thomas
Mueller, Ursula
[Ulmschneider, Sarah]
[Hartmann, Rolf]
2003Poster
Docking of Bacterial Cell-Wall Fragments into Glycopeptide Antibiotics
In: From Genes to Drugs via Crystallography: 33rd crytallographic course at the E. Majorana Center, 49
Kämper, Andreas
[Apostolakis, Joannis]
Lengauer, Thomas
[Borkakoti, Neera]2002Poster
Docking of Ligands into Artificial ReceptorsKämper, Andreas
[Apostolakis, Joannis]
[Rarey, Matthias]
[Marian, Christel Maria]
Lengauer, Thomas
2001Miscellaneous
Docking of Ligands into Artificial Receptors
In: Electronically Excited Molecules: Structure and Dynamics, 37th Symposium for Theoretical Chemistry, P76
[Kämper, Andreas]
[Apostolakis, Joannis]
[Rarey, Matthias]
[Marian, Christel Maria]
[Lengauer, Thomas]
2001Proceedings Article
Docking of Ligands into Molecular Tweezers and Molecular Clips
In: Workshop of the SFB 624 'Templates', ?-?
Kämper, Andreas
Lengauer, Thomas
2002Poster
Docking of monosaccharids into the wild type and mutants of pyranose 2-oxidase
Universität des Saarlandes
Hobler, Anna2006Thesis - Bachelor thesis
Docking studies to investigate the effect of correlated mutations in the HIV-Protease on the drug resistance of HIV
Universität des Saarlandes
Reimer, Daniela2006Thesis - Bachelor thesis
Docking studies to investigate the effect of correlated mutations in the HIV-Protease on the drug resistance of HIV
Universität des Saarlandes
Djoumbou, Yannick2005Thesis - Bachelor thesis
Dynamic escape of pre-existing raltegravir-resistant HIV-1 from raltegravir selection pressure
In: Antiviral Research [88], 281-286
[Codoñer, Francisco M]
[Pou, Christian]
Thielen, Alexander
[García, Federico]
[Delgado, Rafael]
[Dalmau, David]
[Santos, José Ramon]
[Buzón, Maria José]
[Martínez-Picado, Javier Alvarez-Tejado, Miguel]
[Clotet, Bonaventura]
[Ruiz, Lidia]
[Paredes, Roger]
2010Journal Article
Dynamics of NRTI resistance mutations during therapy interruption
In: AIDS Research and Human Retroviruses [25], 57-64
[Trignetti, Maria]
Sing, Tobias
[Svicher, Valentina]
[Santoro, Maria Mercedes]
[Forbici, Federica]
[D'Arrigo, Roberta]
[Bellocchi, Maria Concetta]
[Santoro, Mario]
[Marconi, Patrizia]
[Zaccarelli, Mauro]
[Trotta, Maria Paola]
[Bellagamba, Rita]
[Narciso, Pasquale]
[Antinori, Andrea]
Lengauer, Thomas
[Perno, Carlo Federico]
[Ceccherini-Silberstein, Francesca]
2009Journal Article
Attachment IconDynaPred: A structure and sequence based method for the prediction of MHC class I binding peptide sequence and conformations
In: Bioinformatics [22], 16-24
Antes, Iris
Siu, Shirley Weng-In
Lengauer, Thomas
2006Journal Article
ECLIPPSE: Environment for Chemical Library Inspection, Pre- and Postprocessing, and Screening Evaluation. User GuideKämper, Andreas
Lengauer, Thomas
2003Manual
Attachment IconEditorial: Selection of papers of the German Conference of Bioinformatics (GCB) 2005
In: Bioinformatics [22], 1
[Torda, Andrew E.]
Lengauer, Thomas
2006Journal Article
Effect of ribavirin on the frequency of RNAse L cleavage sites within the hepatitis C viral genome
In: Journal of Viral Hepatitis [17], 217-221
[Mihm, Ulrike]
[Hofmann, W.P.]
Welsch, Christoph
[Polta, A.]
Lengauer, Thomas
[Zeuzem, Stefan]
[Sarrazin, Christoph]
[Herrmann, E.]
2010Journal Article
Effects of sequencing errors on geno2pheno[coreceptor] predictions
In: Abstract Book 11th European Meeting on HIV & Hepatitis, 23-24
Pironti, Alejandro
Lengauer, Thomas
Pfeifer, Nico
2013Poster
Efficacy of antiretroviral therapy switch in HIV-infected patients: A 10-year analysis of the EuResist cohort
In: Intervirology [55], 160-166
[Oette, Mark]
[Schulter, Eugen]
[Rosen-Zvi, Michal]
[Peres, Yardena]
[Zazzi, Maurizio]
[Sonnerborg, Anders]
[Struck, Daniel]
Altmann, Andre
[Kaiser, Rolf]
2012Journal Article
Efficient Clustering Methods for Tumor Classification with Microarrays
In: Proceedings of the 26th Annual Conference of the Gesellschaft für Klassifikation, 670-679
Rahnenführer, Jörg[Schader, Martin]
[Gaul, Wolfgang]
[Vichi, Maurizio]
2003Proceedings Article
Efficient conformational analysis of synthetic receptors with macrocyclic and fused ring systems
In: Synthetic Receptors 2005: Second World Congress on Synthetic Receptors, O4
Kämper, Andreas
Kaspar, Melanie
Lengauer, Thomas
2005Proceedings Article
Efficient Online Transcription Factor Binding Site Adjustment by Integrating Transitive Graph Projection with MoRAine 2.0
In: Special Issue: 6th International Symposium on Integrative Bioinformatics, 117,1-117,11
[Wittkop, Tobias]
[Rahmann, Sven]
Baumbach, Jan
2010Electronic Proceedings Article
Attachment IconEndogenous or exogenous spreading of HIV-1 in Nordrhein-Westfalen, Germany, investigated by phylodynamic analysis of the RESINA Study cohort
In: Medical Microbiology and Immunology [201], 259-269
Lawyer, Glenn
[Schülter, Eugen]
[Kaiser, Rolf]
[Reuter, Stefan]
[Oette, Mark]
Lengauer, Thomas
2012Journal Article
Ensemble methods for classification in cheminformatics
In: Journal of Chemical Information and Modeling [44], 1971-1978
Merkwirth, Christian
[Mauser, H.]
[Schulz-Gasch, T.]
[Roche, O.]
[Stahl, M.]
Lengauer, Thomas
2004Journal Article
Env-wide analysis of coreceptor determining sites and subtype-specific differences in HIV-1
Universität des Saarlandes
König, Eva2010Thesis - Bachelor thesis
Attachment IconEpiExplorer: live exploration and global analysis of large epigenomic datasets
In: Genome Biology [13], R96,1-R96,14
Halachev, Konstantin
[Bast, Hannah]
Albrecht, Felipe
Lengauer, Thomas
Bock, Christoph
2012Electronic Journal Article
EpiExplorer: live exploration and global analysis of large epigenomic datasets
In: Genome Biology [13], R96,1-R96,14
Halachev, K.
[Bast, H.]
Albrecht, F.
Lengauer, Thomas
Bock, Christoph
2012Journal Article
Attachment IconEpigenetic biomarker development
In: Epigenomics [1], 99-110
Bock, Christoph2009Journal Article
Epigenom-Karten erstellen und nutzen
In: BIOspektrum [18], 138-141
Bock, Christoph
Lengauer, Thomas
2012Journal Article
EpiGRAPHregression: A toolkit for (epi-)genomic correlation analysis and prediction of quantitative attributes
Universität des Saarlandes
Halachev, Konstantin2006Thesis - Masters thesis
Attachment IconEpiGRAPH: user-friendly software for statistical analysis and prediction of (epi)genomic data
In: Genome Biology [10], R14.1-R14.14
Bock, Christoph
Halachev, Konstantin
Büch, Joachim
Lengauer, Thomas
2009Journal Article
Erosion of dosage compensation impacts human iPSC disease modeling
In: Cell Stem Cell [10], 595-609
[Mekhubad, Shila]
Bock, Christoph
[de Boer, A. Sophie]
[Kiskinis, Evangelos]
[Meissner, Alexander]
[Eggan, Kevin]
2012Journal Article
Attachment IconErratum to: Prevalence and characteristics of hepatitis B and C virus infections in treatment-naïve HIV-infected patients.
In: Medical Microbiology and Immunology [200], 51-51
[Reuter, Stefan]
[Oette, Mark]
[Wilhelm, Frank Clemens]
Beggel, Bastian
[Kaiser, Rolf]
[Balduin, Melanie]
[Schweitzer, Finja]
[Verheyen, Jens]
[Adams, Ortwin]
Lengauer, Thomas
[Faetkenheuer, Gerd]
[Pfister, Herbert]
[Haeussinger, Dieter]
2011Journal Article
Estimating and Using the Uncertainty in the Phenotypic Resistance Assay of the Hepatitis B Virus to Improve IC-50 Prediction from Genotype
Universität des Saarlandes
Reuter, Kerstin2011Thesis - Bachelor thesis
Estimating cancer survival and clinical outcome based on genetic tumor progression scores
In: Bioinformatics [21], 2438-2446
Rahnenführer, Jörg
Beerenwinkel, Niko
[Schulz, Wolfgang A.]
[Hartmann, Christian]
[von Deimling, Andreas]
[Wullich, Bernd]
Lengauer, Thomas
2005Journal Article
Estimating effective drug combinations against drug-resistant mutants from genotypes
In: Proceedings of the 1st European HIV Drug Resistamce Workshop, 18-18
Beerenwinkel, Niko
[Däumer, Martin]
[Kaiser, Rolf]
[Walter, Hauke]
[Korn, Klaus]
[Hoffmann, Daniel]
[Selbig, Joachim]
Lengauer, Thomas
2003Proceedings Article
Estimating evolutionary pathways to 7CXCR4 usage from cross-sectional data
In: Abstracts presented at the XVIII International HIV Drug Resistance Workshop : Basic Principles & Clinical Implications, A16-A16
Thielen, Alexander
Altmann, André
Bogojeska, Jasmina
[Kaiser, Rolf]
Lengauer, Thomas
2009Poster
Estimating HIV evolutionary pathways and the genetic barrier to drug resistance
In: The Journal of Infectious Diseases [191], 1953-1960
Beerenwinkel, Niko
[Däumer, Martin]
Sing, Tobias
Rahnenführer, Jörg
Lengauer, Thomas
[Selbig, Joachim]
[Hoffmann, Daniel]
[Kaiser, Rolf]
2005Journal Article
Estimating the local variance of protein structure models
Universität des Saarlandes
Weisser, Hendrik2007Thesis - Masters thesis
Etravirine in protease inhibitor-free antiretroviral combination therapies
In: Journal of the International AIDS Society, 155-156
[Schuelter, Eugen]
[Lübcke, Nadine]
[Jensen, Björn]
[Zazzi, Maurizio]
[Sönnerborg, Anders]
Lengauer, Thomas
[Incardona, Francesca]
[Camacho, Richardo]
[Schmit, J]
[Clotet, Bonaventura]
[Kaiser, Rolf]
Pironti, Alejandro
[Kippax, Susan]
[Salif Sow, Papa]
[Wainberg, Mark]
[Heidari, Shirin]
2012Poster
EuResist: exploration of multiple modeling techniques for prediction of response to treatment
In: Proceedings of the 5th European HIV Drug Resistance Workshop, -
[Zazzi, Maurizio]
[Aharoni, Ehud]
[Altmann, Andre]
[Baszó, Fulop]
[Bidgood, Penny]
[Borgulya, Gabór]
[Denholm-Prince, J]
[Fielder, M]
[Kaiser, Rolf]
[Kent, Carmel]
[Lengauer, Thomas]
[Nepusz, T]
[Neuvirth, Hanni]
[Peres, Yardena]
[Petroczi, Andrea]
[Prosperi, Mattia]
[Romano, L]
[Rosen-Zvi, Michal]
[Schülter, Eugen]
Sing, Tobias
[Sonnerborg, Andras]
[Thompson, R]
[Ulivi, G]
[Zalány, L]
[Incardona, Francesca]
2007Poster
European Journal of Medical ResearchLengauer, Thomas
[Oette, M.]
[Selbig, J.]
[Hoffmann, D.]
[Poggensee, G.]
[Hamouda, O.]
[Häussinger, D.]
[Kaiser, R.]
2007Journal
Evidence for Reductive Genome Evolution and Lateral Acquisition of Virulence Functions in two Corynebacterium pseudotuberculosis strains
In: PLoS One [6], e18551
[Ruiz, Jeronimo C.]
[D'Afonseca, Vivian]
[Silva, Artur]
[Ali, Amjad]
[Pinto, Anne C.]
[Santos, Anderson R.]
[Rocha, Aryanne A. M. C.]
[Lopes, Debora O.]
[Dorella, Fernanda A.]
[Pacheco, Luis G. C.]
[Costa, Marcilia P.]
[Turk, Meritxell Z.]
[Seyffert, Nubia]
[Moraes, Pablo M. R. O.]
[Soares, Siomar C.]
[Almeida, Sintia S.]
[Castro, Thiago L. P.]
[Abreu, Vinicius A. C.]
[Trost, Eva]
Baumbach, Jan
[Tauch, Andreas]
[Schneider, Maria P. C.]
[McCulloch, John]
[Cerdeira, Louise T.]
[Ramos, Rommel T. J.]
[Zerlotini, Adhemar]
[Dominitini, Anderson]
[Resende, Daniela M.]
[Coser, Elisangela M.]
[Oliveira, Luciana M.]
[Pedrosa, Andre L.]
[Vieira, Carlos U.]
[Guimaraes, Claudia T.]
[Bartholomeu, Daniela C.]
[Oliveira, Diana M.]
[Santos, Fabricio R.]
[Rabelo, Elida Mara]
[Lobo, Francisco P.]
[Franco, Gloria R.]
[Costa, Ana Flavia]
[Castro, Ieso M.]
[Dias, Silvia Regina]
[Ferro, Jesus A.]
[Ortega, Jose Miguel]
[Paiva, Luciano V.]
[Goulart, Luiz R.]
[Almeida, Juliana Franco]
[Ferro, Maria Ines]
[Carneiro, Newton P.]
[Falcao, Paula R. K.]
[Grynberg, Priscila]
[Teixeira, Santuza M. R.]
[Brommonschenkel, Sergio]
[Oliveira, Sergio C.]
[Meyer, Roberto]
[Moore, Robert J.]
[Miyoshi, Anderson]
[Oliveira, Guilherme C.]
[Azevedo, Vaco]
2011Electronic Journal Article
Evolucion de la Evolucionalidad
In: Biologos lejos del equilibrio: Nuevas metaforas evolutivas, 59-87
Ramírez, FidelRamírez, Fidel
[Balbin, Alejandro]
[Betancourt-Morales, Andres]
[Mora-Oberlaender, Julian]
[Angel-Rodriguez, Melina]
2004Part of a Book
Evolution of Drug Resistance in HIV
In: Bioinformatics - From Genomes to Therapies 3. The Holy Grail: Molecular Function, 1457-1496
Roomp, KirstenLengauer, Thomas2007Part of a Book
Evolution of HIV resistance during treatment interruption in experienced patients and after restarting a new therapy
In: J Clin Virol [34], 277-287
[Balduin, Melanie]
Beerenwinkel, Niko
[Sierra, Saleta]
[Däumer, Martin]
[Rockstroh, Jürgen]
[Oette, Mark]
[Fätkenheuer, Gerd]
[Kupfer, Bernd]
[Hoffmann, Daniel]
[Selbig, Joachim]
[Pfister, Herbert]
[Kaiser, Rolf]
2005Journal Article
Evolution of raltegravir resistance during therapy
In: Journal of antimicrobial chemotherapy [64], 25-32
[Sichtig, Nadine]
[Sierra, Saleta]
[Kaiser, Rolf]
[Däumer, Martin]
[Reuter, Stefan]
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Altmann, André
[Fätkenheuer, Gerd]
[Dittmer, Ulf]
[Pfister, Herbert]
[Esser, Stefan]
2009Journal Article
Attachment IconExpression analysis for inflammatory bowel disease
In: Proceedings of the n?th Conference on, ?
Hahn, Andreas
[Costello, Christine M.]
[Lu, Tim]
Lengauer, Thomas
[Schreiber, Stefan]
2002Poster
Expression analysis for inflammatory bowel disease
In: Workshop Poster Competition, ?
Hahn, Andreas
[Costello, Christine M.]
[Lu, Tim]
Lengauer, Thomas
[Schreiber, Stefan]
2004Poster
Expression and Functional Analyses of Novel Mutations ot ATP-Binding Cassette Transporter-1 in Japanese Patients with High-Density Lipoprotein Deficiency
In: Biochemical and Biophysical Research Communications [290], 713-721
[Nishida, Yoshiharu]
[Hirano, Kenichi]
[Tsukamoto, Kosuke]
[Nagano, Makoto]
[Ikegami, Chiaki]
Roomp, Kirsten
[Ishihara, Mitsuaki]
[Sakane, Naoki]
[Zhang, Zhongyan]
[Tsujii, Ken-ichi]
[Matsuyama, Akifumi]
[Ohama, Tohru]
[Matsuura, Fumihiko]
[Ishigami, Masato]
[Sakai, Naohiko]
[Hiraoka, Hisatoyo]
[Hattori, Hiroaki]
[Wellington, Cheryl L.]
[Yoshida, Yoshihide]
[Misugi, Susumu]
[Hayden, Michael R.]
[Egashira, Toru]
[Yamashita, Shizuya]
[Matsuzawa, Yuji]
2002Journal Article
Attachment IconExpression pattern analysis of transcribed HERV sequences is complicated by ex vitvo recombination
In: Retrovirology [4], 39
[Flockerzi, Aline]
Maydt, Jochen
[Frank, Oliver]
[Ruggieri, Alessia]
[Maldener, Esther]
[Seifarth, Wolfgang]
[Medstrand, Patrik]
Lengauer, Thomas
[Meyerhans, Andreas]
[Leib-Mosch, Christine]
[Meese, Eckart]
[Mayer, Jens]
2007Journal Article
Extension and robustness of Transitivity Clustering for protein-protein interaction network analysis
In: Internet Mathematics [7], 255-273
[Wittkop, Tobias]
[Rahmann, Sven]
Roettger, Richard
[Boecker, Sebastian]
Baumbach, Jan
2011Journal Article
Extracting pathways from biological networks incorporating omics data, introducing a webinterface for KeyPathwayMiner
Universität des Saarlandes
Müller, Joachim2012Thesis - Masters thesis
Extracting Sets of Chemical Substructures and Protein Domains Governing Drug-Target Interactions
In: Journal of Chemical Information and Modeling [51], 1183-1194
[Yamanishi, Yoshihiro]
[Pauwels, Edouard]
Saigo, Hiroto
[Stovent, Veronique]
2011Journal Article
Attachment IconFactor interaction analysis for chromosome 8 and DNA methylation alterations highlights innate immune response suppression and cytoskeletal changes in prostate cancer
In: Molecular Cancer [6], 1-16
[Schulz, Wolfgang A.]
Alexa, Adrian
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[Hader, Christiane]
[Hoffmann, Michele J.]
[Yamanaka, Masanori]
[Fritzsche, Sandy]
[Wlazlinski, Agnes]
[Müller, Mirko]
Lengauer, Thomas
[Engers, Rainer]
[Florl, Andrea R.]
[Wullich, Bernd]
Rahnenführer, Jörg
2007Journal Article
Feature Prints: A new method for calculating molecular similarities
Universität des Saarlandes
Binsl, Thomas2006Thesis - Masters thesis
Fifteen years of env C2V3C3 evolution in six individuals clonally infected with human immunodeficiency virus type 1
In: Journal of Medical Virology [79], 1629-1639
[Kupfer, Bernd]
Sing, Tobias
Schüffler, Peter
[Hall, Rabea]
[Kurz, Ralf]
[McKeown, Astrid]
[Schneweis, Karl-Eduard]
[Eberl, Wolfgang]
[Oldenburg, Johannes]
[Brackmann, Hans H.]
[Rockstroh, Jürgen K.]
[Spengler, Ulrich]
Däumer, Martin
[Kaiser, Rolf]
Lengauer, Thomas
[Matz, Bertfried]
2007Journal Article
Finding local similarities in gene expression patterns between partially reprogrammed cells and know cell types using a module network approach
Universität des Saarlandes
Perner, Juliane2010Thesis - Masters thesis
Finding Regions of Aberrant DNA Copy Number Associated With Tumor Phenotype
Universität des Saarlandes
Tolosi, Laura2012Thesis - PhD thesis
Finding scaffold proteins in interactomes
In: Trends in Cell Biology [20], 2-4
Ramírez, Fidel
Albrecht, Mario
2010Journal Article
Finding the Hairpin in the Haystack: Towards an High Throughput in Silico Pipeline for Aptamer Motif Identification using SELEX Data
Universität des Saarlandes
Hoinka, Jan-Malte2011Thesis - Masters thesis
Finite iteration DT-CNN - new design and operation principles
In: Proceedings (ISCAS-04) : 2004 IEEE International Symposium on Circuits and Systems. - Vol. 5, Blind signal processing, computer-aided network design, invited sessions, neural sytems and applications, power systems and power electronic circuits, 504-507
Merkwirth, Christian
[Bröcker, J.]
[Ogorzalek, Maciej]
Wichard, J.D.
2004Proceedings Article
Finite iteration DT-CNN with stationary templates
In: Proceedings of the 8th IEEE International Workshop on Cellular Neural Networks and their Applications (CNNA 2004), 459-464
[Wichard, J.D.]
[Ogorzalek, Maciej]
Merkwirth, Christian
[Bröcker, J.]
2004Proceedings Article
FlexE: Efficient Molecular Docking Considering Protein Structure Variations
In: Journal of Molecular Biology [308], 377-395
Claussen, C.
Buning, Christian
[Rarey, Matthias]
Lengauer, Thomas
2001Journal Article
Flexible Docking of Ligands into Synthetic Receptors Using a Two-Sided Incremental Construction Algorithm
In: Journal of Chemical Information and Modeling [46], 1695-1703
Steffen, Andreas
Kämper, Andreas
Lengauer, Thomas
2006Journal Article
Flexible docking under pharmacophore type constraints
In: Journal of Computer-Aided Molecular Design [16], 129-149
[Hindle, Sally A.]
[Rarey, Matthias]
[Buning, Christian]
Lengauer, Thomas
2002Journal Article
FlexR - A new tool for predicting the structure of synthetic host-guest complexes
In: Synthetic Receptors 2005: Second World Congress on Synthetic Receptors, O7
Steffen, Andreas
Kämper, Andreas
Lengauer, Thomas
Turner, A.P.F.2005Proceedings Article
FlexR - Predicting the structure of host-guest complexes
In: Proceedings of the Annual Meeting of the German Pharmaceutical Society - Joint Meeting 2004 (DPhG 2004), 130
Steffen, Andreas
Kämper, Andreas
Lengauer, Thomas
2004Poster
From Genomes to DrugsLengauer, Thomas2001Book
Attachment IconFrom Protein Structure to Function
Universität des Saarlandes
Sommer, Ingolf2009Thesis - Habilitation thesis
Full genome ultra-deep pyrosequencing associates G-to-A-hypermutation of the hepatitis B virus genome with the natural progression of hepatitis B
In: Journal of Viral Hepatitis [12], 882-889
Beggel, Bastian
[Münk, C.]
[Däumer, M.]
[Hauck, K.]
[Häussinger, D.]
Lengauer, Thomas
[Ehrhardt, A.]
2013Journal Article
Fully Automated Flexible Docking of Ligands into Flexible Synthetic Receptors Using Forward and Inverse Docking Strategies
In: Journal of Chemical Information and Modeling [46], 903-911
Kämper, Andreas
[Apostolakis, Joannis]
[Rarey, Matthias]
[Marian, Christel Maria]
Lengauer, Thomas
2006Journal Article
Attachment IconFun2Struc-A Tool For Predicting Protein Structure
Classes from Function Predictions
Universität des Saarlandes
Eyrisch, Susanne2004Thesis - Bachelor thesis
Attachment IconFunctional Analysis of a Potassium-Chloride Co-Transporter 3 (SLC12A6) Promoter Polymorphism Leading to an Additional DNA Methylation Site
In: Neuropsychopharmacology [34], 458-467
[Moser, Dirk]
[Ekawardhani, Savira]
[Kumsta, Robert]
[Palmason, Haukur]
Bock, Christoph
[Athanassiadou, Zoi]
[Lesch, Klaus-Peter]
[Meyer, Jobst]
2009Journal Article
Functional characterization of human genes from exon expression and RNA interference results
In: Bioinformatics and Drug Discovery, 33-53
Emig, Dorothea
Blankenburg, Hagen
Ramírez, Fidel
Albrecht, Mario
[Larson, Richard S]2012Part of a Book
Attachment IconFunctional evaluation of domain-domain interactions and human protein interaction networks
In: Bioinformatics [23], 859-865
Schlicker, Andreas
Huthmacher, Carola
Ramírez, Fidel
Lengauer, Thomas
Albrecht, Mario
2007Journal Article
Functional evaluation of domain-domain interactions and human protein interaction networks
In: German Conference on Bioinformatics (GCB 2006), 115-126
Schlicker, Andreas
Huthmacher, Carola
Ramírez, Fidel
Lengauer, Thomas
Albrecht, Mario
[Huson, Daniel]
[Kohlbacher, Oliver]
[Lupas, Andrei]
[Nieselt, Kay]
[Zell, Andreas]
2006Proceedings Article
Functional Profiling in Metagenomics
Universität des Saarlandes
Weimann, Aaron2011Thesis - Masters thesis
Functional Site Scaffolds
Universität des Saarlandes
Zimmer, Tobias2006Thesis - Bachelor thesis
FunSimMat update: new features for exploring functional similarity
In: Nucleic Acids Research [38], D244-D248
Schlicker, Andreas
Albrecht, Mario
2010Journal Article
Attachment IconFunSimMat: a comprehensive functional similarity database
In: Nucleic Acids Research [36], D434-D439
Schlicker, Andreas
Albrecht, Mario
2008Journal Article
Future Trends
In: Bioinformatics - From Genomes to Therapies 3. The Holy Grail: Molecular Function, 1651-1687
Lengauer, ThomasLengauer, Thomas2007Part of a Book
Attachment IconGenerating Frequency Profiles from Multiple
Structure Alignments
Universität des Saarlandes
Weiss, Julia2005Thesis - Bachelor thesis
Attachment IconGenerating Molecular Hashcodes for
Finding Duplicates in Virtual Screening
Libraries
Universität des Saarlandes
Nickels, Stefan2005Thesis - Bachelor thesis
Genetic variation in DLG5 is associated with inflammatory bowel disease
In: Nature Genetics [36], 376-380
[Stoll, Monika]
[Corneliussen, Brit]
[Costello, Christine M.]
[Waetzig, Georg H.]
[Mellgard, Bjorn]
[Koch, W. Andreas]
[Rosenstiel, Philip]
Albrecht, Mario
[Croucher, Peter J.P.]
[Seegert, Dirk]
[Nikolaus, Susanna]
[Hampe, Jochen]
Lengauer, Thomas
[Pierrou, Stefan]
[Foelsch, Ulrich R.]
[Mathew, Christopher G.]
[Lagerstrom-Fermer, Maria]
[Schreiber, Stefan]
2004Journal Article
Genetics of Crohn disease, an archetypal inflammatory barrier disease
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[Schreiber, Stefan]
[Rosenstiel, Philip]
Albrecht, Mario
[Hampe, Jochen]
[Krawczak, Michael]
2005Journal Article
GenLab: Laboratorio virtual de genetica
In: Acta Biologica Colombiana [5], 45-48
Ramírez, Fidel
[Garcia, Sergio]
2000Journal Article
Geno2pheno is predictive of short-term virological response
In: Proceedings from the 5th International Workshop on HIV Drug Resistance & Treatment Strategies, 74-74
Beerenwinkel, Niko
Lengauer, Thomas
[Däumer, Martin]
[Sierra, S.]
[Schmidt, Barbara]
[Walter, Hauke]
[Korn, Klaus]
[Oette, Mark]
Fätkenheuer, Gerd
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[Kaiser, Rolf]
[Selbig, Joachim]
2002Proceedings Article
Geno2pheno: a new machine learning approach to predicting phenotypic drug resistance from genotype
In: Antiviral Therapy [6], 104
Lengauer, Thomas
[Beerenwinkel, Niko]
[Schmidt, B.]
[Walter, H.]
[Kaiser, R.]
[Hoffmann, D.]
[Korn, K.]
[Selbig, J.]
2001Journal Article
Geno2pheno: A system for the interpretation of genotypic HIV Drug resistance tests
In: IEEE Intelligent Systems [16], 35-41
Beerenwinkel, Niko
[Schmidt, Barbara]
[Walter, Hauke]
[Kaiser, Rolf]
Lengauer, Thomas
[Hoffmann, Daniel]
[Korn, Klaus]
[Selbig, Joachim]
2001Journal Article
Geno2pheno: estimating phenotypic drug resistance from HIV-1 genotypes
In: Nucleic Acids Research [31], 3850-3855
Beerenwinkel, Niko
[Däumer, Martin]
[Oette, Mark]
[Korn, Klaus]
[Hoffmann, Daniel]
[Kaiser, Rolf]
Lengauer, Thomas
[Selbig, Joachim]
[Walter, Hauke]
2003Journal Article
Geno2pheno[454]: A Web Server for the Prediction of HIV-1 Coreceptor Usage from Next-Generation Sequencing Data
In: Intervirology [55], 113-117
Thielen, Alexander
Lengauer, Thomas
2012Journal Article
Geno2pheno[coreceptor]: a tool for predicting coreceptor usage from genotype and for monitoring coreceptor-associated sequence alterations
In: Proceedings of the 3rd European HIV Drug Resistance Workshop, -
Sing, Tobias
Beerenwinkel, Niko
[Kaiser, Rolf]
[Hoffmann, Daniel]
[Däumer, Martin]
Lengauer, Thomas
2005Poster
Attachment IconGenome-scale DNA methylation mapping of clinical samples at single-nucleotide resolution
In: Nature Methods [7], 133-136
[Gu, Hongcang]
Bock, Christoph
[Mikkelsen, Tarjei S.]
[Jäger, Natalie]
[Smith, Zachary D.]
[Tomazou, Eleni]
[Gnirke, Andreas]
[Lander, Eric S.]
[Meissner, Alexander]
2010Journal Article
Genome-wide association study for ulcerative colitis identifies risk loci at 7q22 and 22q13 (IL17REL)
In: Nature Genetics [42], 292-294
[Franke, Andre]
[Balschun, Tobias]
[Sina, Christian]
[Ellinghaus, David]
[Häsler, Robert]
Mayr, Gabriele
Albrecht, Mario
[Wittig, Michael]
[Buchert, Eva]
[Nikolaus, Susanna]
[Gieger, Christian]
[Wichmann, H. Erich]
[Sventoraityte, Jurgita]
[Kupcinskas, Limas]
[Onnie, Clive M.]
[Gazouli, Maria]
[Anagnou, Nicholas P.]
[Strachan, David]
[McArdle, Wendy L.]
[Mathew, Christopher G.]
[Rutgeerts, Paul]
[Vermeire, Séverine]
[Vatn, Morten H.]
[Krawczak, Michael]
[Rosenstiel, Philip]
[Karlsen, Tom H.]
[Schreiber, Stefan]
2010Journal Article
Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2
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[Ellinghaus, Eva]
[Ellinghaus, David]
[Stuart, Philip E.]
[Nair, Rajan P.]
[Debrus, Sophie]
[Raelson, John V.]
[Belouchi, Majid]
[Fournier, Hélène]
[Reinhard, Claudia]
[Ding, Jun]
[Li, Yun]
[Tejasvi, Trilokraj]
[Gudjonsson, Johann]
[Stoll, Stefan W.]
[Voorhees, John J.]
[Lambert, Sylviane]
[Weidinger, Stephan]
[Eberlein, Bernadette]
[Kunz, Manfred]
[Rahman, Proton]
[Gladman, Dafna D.]
[Gieger, Christian]
[Wichmann, H. Erich]
[Karlsen, Tom H.]
Mayr, Gabriele
Albrecht, Mario
[Kabelitz, Dieter]
[Mrowietz, Ulrich]
[Abecasis, Gonçalo R.]
[Elder, James T.]
[Schreiber, Stefan]
[Weichenthal, Michael]
[Franke, Andre]
2010Journal Article
Genome Signature based Sequence Comparison for Taxonomic Assignment and tree inference
Universität des Saarlandes
Patil, Kaustubh Raosaheb2013Thesis - PhD thesis
Genomic distribution and inter-sample variation of non-CpG methylation across human cell types
In: PLoS Genetics [17], e1002389,1-e1002389,15
[Ziller, Michael J.]
Müller, Fabian
[Liao, Jing]
[Zhang, Yingying]
[Gu, Hongcang]
Bock, Christoph
[Boyle, Patrick]
[Epstein, Charles B.]
[Bernstein, Bradley E.]
Lengauer, Thomas
[Gnirke, Andreas]
[Meissner, Alexander]
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Genomic organization of the human tissue inhibitor of metalloproteinases-3 (TIMP3)
In: Genome Research [5], 483-7
[Stohr, H.]
Roomp, Kirsten
[Felbor, U.]
[Weber, B. H.]
1995Journal Article
Genotypic Analysis of HIV-1 Coreceptor Usage
Universität des Saarlandes
Thielen, Alexander2011Thesis - PhD thesis
Genotypic Analysis of HIV Co-Receptor Usage
In: Entry Inhibitoren - Neue Formen der HIV-Therapie, 31-39
[Sierra, Saleta]
[Kaiser, Rolf]
Thielen, Alexander
[Sander, Oliver]
Lengauer, Thomas
[Jäger, Hans]2008Part of a Book
Attachment IconGenotypic coreceptor analysis.
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[Sierra, Saleta]
[Kaiser, Rolf]
Thielen, Alexander
Lengauer, Thomas
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Genotypic determination of HIV-1 tropism in the clinical setting
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Genotypic tropism testing by massively parallel sequencing: qualitative and quantitative analysis
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Lengauer, Thomas
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Thielen, Alexander
2011Electronic Journal Article
Genotyping hepatitis B virus dual infections using population-based sequence data
In: Journal of General Virology [9], 1899-1907
Beggel, Bastian
[Neumann-Fraune, Maria]
[Doering, Matthias]
Lawyer, Glenn
[Kaiser, Rolf]
[Verheyen, Jens]
Lengauer, Thomas
2012Journal Article
GOdot Sequence - function prediction from protein sequence
Universität des Saarlandes
Gatzmann, Fanny2010Thesis - Bachelor thesis
Attachment IconGOTax: investigating biological processes and biochemical activities along the taxonomic tree
In: Genome Biology [8], R33.1-10
Schlicker, Andreas
Rahnenführer, Jörg
Albrecht, Mario
Lengauer, Thomas
Domingues, Francisco S.
2007Electronic Journal Article
Grey and white matter proportional relationships in the cerebellar vermis altered in schizophrenia
In: Cerebellum [8], 52-60
[Lawyer, Glenn]
[Nesvåg, Ragnar]
[Varnäs, Katarina]
[Okugawa, Gaku]
[Agartz, Ingrid]
2009Journal Article
Hacia una comprension de la accion de la recombinacion genetica y la mutacion en el origen de la variacion fenotipica, mediante el analisis de la computacion evolutiva
Universidad Nacional de Colombia
Ramírez, Fidel2004Thesis - Masters thesis
Attachment IconHepatitis B virus reverse transcriptase sequence variant database for sequence analysis and mutation discovery
In: Antiviral Research [88], 269-275
[Rhee, Soo-Yon]
[Margeridon-Thermet, Severin]
[Nguyen, Mindie]
[Liu, Tommy]
[Kagan, Ron]
Beggel, Bastian
[Verheyen, Jens]
[Kaiser, Rolf]
[Shafer, Robert]
2010Journal Article
Heteroaryl-substituted naphthalenes and structurally modified derivatives: selective inhibitors of CYP11B2 for the treatment of congestive heart failure and myocardial fibrosis
In: Journal of Medicinal Chemistry [48], 6632-6642
[Voets, Marieke]
Antes, Iris
[Scherer, C]
[Mueller-Vieira, U.]
[Biemel, K.]
[Barrassin, C.]
[Marchais-Oberwinkler, S.]
[Hartmann, R. W.]
2005Journal Article
Hierarchical Bayes Model for Predicting Effectiveness of HIV Combination Therapies
In: Statistical Applications in Genetics and Molecular Biology [11], 11.1-11.19
Bogojeska, Jasmina
Lengauer, Thomas
2012Journal Article
High Concordance between the Position-Specific Scoring Matrix and Geno2pheno Algorithms for Genotypic Interpretation of HIV-1 Tropism: V3 Length as the Major Cause of Disagreement
In: Journal of Clinical Microbiology [49], 3380-3382
[Seclen, Eduardo]
[Soriano, Vincente]
[González, Maria M]
[Gómez, Sagrario]
Thielen, Alexander
[Poveda, Eva]
2011Journal Article
High frequency of complex mutational patterns in lamivudine resistant hepatitis B virus isolates
In: Journal of Medical Virology [200], 39-49
[Neumann-Fraune, Maria]
Beggel, Bastian
[Pfister, Herbert]
[Kaiser, Rolf]
[Verheyen, Jens]
2013Journal Article
History-alignment models for bias-aware prediction of virological response to HIV combination therapy
In: Proceedings of the Fifteenth International Conference on Artificial Intelligence and Statistics (AISTATS 2012), 118-126
Bogojeska, Jasmina
[Stöckel, Daniel]
[Zazzi, Maurizio]
[Kaiser, Rolf]
[Incardona, Francesca]
[Rosen-Zvi, Michal]
Lengauer, Thomas
[Lawrence, Neil]
[Girolami, Mark]
2012Proceedings Article
History Based HIV Therapy Outcome Prediction
Universität des Saarlandes
Stöckel, Daniel2010Thesis - Masters thesis
History distribution matching method for predicting effectiveness of HIV combination therapies
In: Neural Information Processing Systems (NIPS 2011), 424-432
Bogojeska, Jasmina[Shawe-Taylor, John]
[Zemel, Richard S.]
[Bartlett, Peter]
[Pereira, Fernando]
[Weinberger, Kilian Q.]
2011Electronic Proceedings Article
HIV-1 fitness landscape models for indinavir treatment pressure using observed evolution in longitudinal sequence data are predictive for treatment failure
In: Infection, Genetics and Evolution [19], 349–360
Pironti, Alejandro2013Journal Article
HIV-1 mutational pathways under multidrug therapy
In: AIDS Research and Therapy [8], 1-13
Lawyer, Glenn
Altmann, André
Thielen, Alex
[Zazzi, Maurizio]
[Sönnerborg, Anders]
Lengauer, Thomas
2011Journal Article
HIV-GRADE: A Publicly Available, Rules-Based Drug Resistance Interpretation Algorithm Integrating Bioinformatic Knowledge
In: Intervirology [55], 102-107
[Obermeier, Martin]
Pironti, Alejandro
[Berg, Thomas]
[Braun, Patrick]
[Däumer, Martin]
[Eberle, Josef]
[Ehret, Robert]
[Kaiser, Rolf]
[Kleinkauf, Niels]
[Korn, Klaus]
[Kücherer, Claudia]
[Müller, Harm]
[Noah, Christian]
[Stürmer, Martin]
Thielen, Alexander
[Wolf, Eva]
[Walter, Hauke]
2012Journal Article
HIV prevalence and route of transmission in Turkish immigrants
living in North-Rhine Westphalia, Germany
In: Medical Microbiology and Immunology [200], 219-223
[Schülter, Eugen]
[Oette, Mark]
[Balduin, Melanie]
[Reuter, Stefan]
[Rockstroh, Jürgen]
[Fätkenheuer, Gerd]
[Esser, Stefan]
Lengauer, Thomas
[Agacfidan, Ali]
[Pfister, Herbert]
[Kaiser, Rolf]
[Akgul, Baki]
2011Journal Article
HIV2EU: supporting standardized HIV-2 drug resistance interpretation in Europe
In: Journal of the International AIDS Society, 135
[Obermeier, Martin]
[Camacho, Ricardo]
[Charpentier, Charlotte]
[Deschamps, Diane]
[Eberle, Joseph]
[Gürtler, Lutz]
[Ruelle, Jean]
Pironti, Alejandro
[Brun-Veziet, Francoise]
[Stürmer, Martin]
[Kaiser, Rolf]
[Kippax, Susan]
[Salif Sow, Papa]
[Wainberg, Mark]
[Heidari, Shirin]
2012Poster
HLA class I allele associations with HCV genetic variants in patients with chronic HCV genotypes 1a or 1b infection
In: Journal of Hepatology [53], 1022-1028
[Lange, Christian Markus]
Roomp, Kirsten
[Dragan, Anette]
[Nattermann, Jacob]
[Michalk, Monika]
[Spengler, Ulrich]
[Weich, Viola]
Lengauer, Thomas
[Zeuzem, Stefan]
[Berg, Thoma]
[Sarrazin, Christoph]
2010Journal Article
How Little Do We Actually Know? - On the Size of Gene Regulatory Networks.
In: IEEE/ACM transactions on computational biology and bioinformatics [9], 1293-1300
Röttger, Richard
[Rueckert, Ulrich]
[Taubert, Jan]
Baumbach, Jan
2012Journal Article
Hybrid clustering for microarray analysis combining intensity and shape features
In: Poster book of the European Conference on Computational Biology, Saarbrücken, Germany 2002, -
Rahnenführer, Jörg2002Poster
Hybrid clustering for microarray image analysis combining intensity and shape features
In: BMC Bioinformatics [5], 1-11
Rahnenführer, Jörg
[Bozinov, Daniel]
2004Journal Article
Attachment IconHyperdiploidy defines a distinct cytogenetic entity of meningiomas
In: Journal of Neuro-Oncology [83], 213-221
[Ketter, Ralf]
[Kim, Yoo-Jin]
[Storck, Simone]
Rahnenführer, Jörg
[Romeike, Bernd F.M.]
[Steudel, Wolf-Ingo]
[Zang, Klaus D.]
[Henn, Wolfram]
2007Journal Article
Identification and in silico characterization of a novel compound heterozygosty associated with hereditary aceruloplasminemia
In: Scandinavian Journal of Gastroenterology [42], 1088-1094
[Hofmann, Wolf Peter]
Welsch, Christoph
[Takahashi, Yoshitomo]
[Miyajima, Hiroaki]
[Mihm, Ulrike]
[Krick, Christoph]
[Zeuzem, Stefan]
[Sarrazin, Christoph]
2007Journal Article
Identification of c-Kit receptor as a regulator of adult neural stem cells in the mammalian eye: interactions with Notch signaling
In: Developmental Biology [273], 87-105
[James, Jackson]
[Das, Ani V.]
[Zhao, Xing]
Rahnenführer, Jörg
[Ahmad, Iqbal]
2004Journal Article
Identification of CYP106A2 as a Regioselective Allylic Bacterial Diterpene Hydroxylase
In: ChemBioChem [12], 576-582
[Bleif, Sabrina]
[Hannemann, Frank]
[Lisurek, Michael]
[von Kries, Jens Peter]
[Zapp, Josef]
Dietzen, Matthias
[Antes, Iris]
[Bernhardt, Rita]
2011Journal Article
Identification of functionally important regions in cytochrome P450 systems and a systematic analysis of various CYP P450 homology models
Universität des Saarlandes
Meiser, Ina2005Thesis - Bachelor thesis
Identification of mammalian orthologs associates PYPAF5 with distinct functional roles
In: FEBS Letters [538], 173-177
Albrecht, Mario
Domingues, Francisco S.
[Schreiber, Stefan]
Lengauer, Thomas
2003Journal Article
Identification of PatL1, a human homolog to yeast P body component Pat1
In: Biochimica et Biophysica Acta - Molecular Cell Research [1773], 1786-1792
[Scheller, Nicoletta]
[Resa-Infante, Patricia]
[de la Luna, Susana]
[Galao, Rui Pedro]
Albrecht, Mario
[Kaestner, Lars]
[Lipp, Peter]
Lengauer, Thomas
[Meyerhans, Andreas]
[Díez, Juana]
2007Journal Article
Identification of rat brahma (rBRM), a subunit of SWI/SNF chromatin remodeling complex: Involvement in the differentiation of retinal stem cells/progenitors[James, Jackson]
Das, Ani V.
Rahnenführer, Jörg
[Leon, FAS]
[Ahmad, Iqbal]
2003Miscellaneous
Identification of Symmetries in Molecules and Complexes
Universität des Saarlandes
Korbel, Ulli S.2007Thesis - Masters thesis
Identifying discriminative motifs for molecular function of proteins
Universität des Saarlandes
Loi, Luu Phuc2010Thesis - Masters thesis
Image analysis for cDNA microarrays
In: Methods of Information in Medicine [44], 405-407
Rahnenführer, Jörg2005Journal Article
Impact of a single amino acid in the variable region 2 of the Old World monkey TRIM5alpha SPRY (B30.2) domain on anti-human immunodeficiency virus type 2 activity
In: Virology [388], 160-168
[Kono, Ken]
Bozek, Kasia
Domingues, Francisco S.
[Shioda, Tatsuo]
[Nakayama, Emi E.]
2009Journal Article
Impact of ribavirin on HCV replicon RNA decline during treatment with interferon-α and the protease inhibitors boceprevir or telaprevir
In: Antiviral Therapy [16], 695-704
[Hofmann, Wolf Peter]
[Chung, Tje Lin]
[Osbahr, Carola]
[Susser, Simone]
[Karey, Ursel]
[Mihm, Ulrike]
Welsch, Christoph
[Lötsch, Jörn]
[Sarrazin, Christoph]
[Zeuzem, Stefan]
[Herrmann, Eva]
2011Journal Article
Attachment IconImplementation of a Generic Fragment
Based Method for Automated
Calculation of the Octanol-Water
Partition Coefficient
Universität des Saarlandes
Binsl, Thomas2004Thesis - Bachelor thesis
Attachment IconImplementation of a method to filter
out compounds with toxic, reactive
and unsuitable functional groups
Universität des Saarlandes
Volkamer, Andrea2005Thesis - Bachelor thesis
Improved cyclodextrin-based receptors for camptothecin by inverse virtual screening
In: Chemistry [13], 6801-6809
Steffen, Andreas
[Thiele, Carolin]
[Tietze, Simon]
[Strassnig, Christian]
Kämper, Andreas
Lengauer, Thomas
[Wenz, Gerhard]
[Apostolakis, Joannis]
2007Journal Article
Improved detection of CXCR4-using HIV by V3 genotyping: application of population-based and "deep" sequencing to plasma RNA and proviral DNA
In: Journal of Acquired Immune Deficiency Syndromes [54], 506-510
[Swenson, Luke C.]
[Moores, Andrew]
[Low, Andrew J.]
Thielen, Alexander
[Dong, Winnie]
[Woods, Conan]
[Jensen, Mark A.]
[Wynhoven, Brian]
[Chan, Dennison]
[Glascock, Christopher]
[Harrigan, P. Richard]
2010Journal Article
Improved detection of X4 virus by V3 genotyping: application to plasma RNA and proviral DNA
In: Antiviral Therapy, A99
[Moores, Andrew]
Thielen, Alexander
[Dong, Winnie]
Low, Andrew J.
[Woods, Conan]
[Jensen, Mark]
[Wynhoven, Brian]
[Chan, Dennison]
[Glascock, Christopher]
[Harrigan, P Richard]
2008Poster
Improved genotypic prediction of HIV-1 coreceptor usage by incorporating V2 loop sequence variation
In: Antiviral Therapy, A100
Thielen, Alexander
[Harrigan, P Richard]
Low, Andrew J.
[Moores, A]
Altmann, Andre
Bozek, Kasia
[Heger, Eva]
[Sichtig, Nadine]
[Kaiser, Rolf]
Lengauer, Thomas
2008Poster
Improved prediction of HIV-1 coreceptor usage with sequence information from the second hypervariable loop of gp120
In: Journal of Infectious Diseases [202], 1435-1443
Thielen, Alexander
[Sichtig, Nadine]
[Kaiser, Rolf]
[Lam, Jeffrey]
[Harrigan, P. Richard]
Lengauer, Thomas
2010Journal Article
Improved prediction of response to antiretroviral combination therapy using the genetic barrier to drug resistance
In: Antiviral Therapy [12], 169-178
Altmann, Andre
[Beerenwinkel, Niko]
Sing, Tobias
Savenkov, Igor
[Däumer, Martin]
[Kaiser, Rolf]
[Rhee, Soo-Yon]
[Fessel, W Jeffrey]
[Shafer, Robert W]
Lengauer, Thomas
2007Journal Article
Attachment IconImproved Scoring of Functional Groups from Gene Expression Data by Decorrelating GO Graph Structure
In: Bioinformatics [22], 1600-1607
Alexa, Adrian
Rahnenführer, Jörg
Lengauer, Thomas
2006Journal Article
Improvement of the fungal enzyme pyranose 2-oxidase using protein engineering
In: Journal of Biotechnology [124], 26-40
[Heckmann-Pohl, Dorothee M.]
[Bastian, Sabine]
[Altmeier, S.]
Antes, Iris
2006Journal Article
Improving coreceptor usage prediction in the clinic using hints from next generation sequencing data
In: Bioinformatics [28], i589-i595
Pfeifer, Nico
Lengauer, Thomas
2012Journal Article
Improving disease gene prioritization using the semantic similarity of Gene Ontology terms
In: Bioinformatics [26], i561-i567
Schlicker, Andreas
Lengauer, Thomas
Albrecht, Mario
2010Journal Article
Attachment IconImproving fold recognition of protein threading by experimental distance constraints
In: In Silico Biology [2], 325-337
Albrecht, Mario
[Hanisch, Daniel]
[Zimmer, Ralf]
Lengauer, Thomas
2002Journal Article
Improving Fold Recognition Using Protein
and Domain Interactions
Universität des Saarlandes
Guo, Xin2006Thesis - Masters thesis
Improving HIV-1 coreceptor usage prediction from genotype with regions outside of V3
In: Reviews in Antiviral Therapy, 81-82
Thielen, Alexander
[Kaiser, Rolf]
Lengauer, Thomas
2008Poster
Attachment IconImproving HIV coreceptor usage prediction in the clinic using hints from next-generation sequencing data
In: Bioinformatics [28], i589-i595
Pfeifer, Nico
Lengauer, Thomas
2012Journal Article
Improving the quality of protein structure models by selecting from alignment alternatives
In: BMC Bioinformatics [7], 1-11
Sommer, Ingolf
[Toppo, Stefano]
Sander, Oliver
Lengauer, Thomas
[Tosatto, Silvio C. E.]
2006Electronic Journal Article
In-depth analysis of G-to-A hypermutation rate in HIV-1 env DNA induced by endogenous APOBEC3 proteins using massively parallel sequencing
In: Journal of Virological Methods [71], 329-338
[Knoepfel, Stefanie]
[Di Giallonardoc, Francesca]
[Däumer, Martin]
Thielen, Alexander
[Metzner, Karin J]
2011Journal Article
In silico analysis of microRNA genes on human chromosome 14 and mouse chromosome 12
Universität des Saarlandes
Kircher, Martin2007Thesis - Masters thesis
In silico analysis of the effects of sequencing errors on geno2pheno[coreceptor]
In: Abstract Book of the International Workshop on HIV&Hepatitis Virus, A142
Pironti, Alejandro
Lengauer, Thomas
Pfeifer, Nico
2013Poster
In Silico Models for the Prediction of Metabolism by Cytochrome P450 Enzymes
Universität des Saarlandes
Mangels, Miriam2009Thesis - Bachelor thesis
Inference of Protein Function based on Functionally Conserved Regions in Sequence and Structure Space
Universität des Saarlandes
Weinhold, Nils2006Thesis - Masters thesis
Inferring physical protein contacts from large-scale purification data of protein complexes
In: Molecular & Cellular Proteomics [10], M110.004929,1-M110.004929,15
Schelhorn, Sven-Eric
Mestre, Julián
Zotenko, Elena
Albrecht, Mario
2011Electronic Journal Article
Inferring Protein Function from Protein Structure
In: Bioinformatics - From Genomes to Therapies 3. The Holy Grail: Molecular Function, 1211-1252
Domingues, Francisco S.
Lengauer, Thomas
Lengauer, Thomas2007Part of a Book
Inferring short-range linkage information from sequencing chromatograms
In: PLoS One,
Beggel, Bastian
Lengauer, Thomas
2013Electronic Journal Article
Inferring viral tropism from genotype with massively parallel sequencing; qualitative and quantitative analysis
In: Antiviral Therapy, A101
Däumer, Martin
[Kaiser, Rolf]
[Klein, Rolf]
Lengauer, Thomas
[Thiele, Bernhard]
Thielen, Alexander
2008Poster
Inferring virological response from genotype: with or without predicted phenotypes?
In: Proceedings of the 16th International HIV Drug Resistance Workshop, S169
Altmann, Andre
Sing, Tobias
[Vermeiren, Hans]
[Winters, Bart]
[Van Craenenbroeck, Elke]
[Van der Borght, Koen]
[Rhee, Soo-Yon]
[Shafer, Robert W]
[Schülter, Eugen]
[Kaiser, Rolf]
[Peres, Yardena]
[Sonnerborg, Anders]
[Fessel, W Jeffrey]
[Incardona, Francesca]
[Zazzi, Maurizio]
[Bacheler, Lee]
[Van Vlijmen, Hermann]
Lengauer, Thomas
2007Poster
Inferring virological response to antiretroviral combination therapy based on past treatment lines
Universität des Saarlandes
Müller, Fabian2008Thesis - Bachelor thesis
Attachment IconInformatics (Computational Biology)
In: Growth Factors and Oncogenes in Gastrointestinal Cancers to Informatics (Computational Biology), 567-626
Lengauer, Thomas[Meyers, Robert A.]2005Part of a Book
Attachment IconIntegrated statistical learning of metabolic ion mobility spectrometry profiles for pulmonary disease identification
In: Genetics and Molecular Research [11], 2733-2744
Hauschild, Anne-Christin
[Baumbach, Jörg Ingo]
Baumbach, Jan
2012Electronic Journal Article
Integrating biological data - the Distributed Annotation System
In: BMC Bioinformatics [9], S3.1-7
[Jenkinson, Andrew M.]
Albrecht, Mario
[Birney, Ewan]
Blankenburg, Hagen
[Down, Thomas]
[Finn, Robert D.]
[Hermjakob, Henning]
[Hubbard, Tim J. P.]
[Jimenez, Rafael C.]
[Jones, Philip]
[Kähäri, Andreas]
[Kulesha, Eugene]
[Macías, José R.]
[Reeves, Gabrielle A.]
[Prlić, Andreas]
2008Journal Article
Integrating expression data with domain interaction networks
In: Bioinformatics [24], 2546-2548
Emig, Dorothea
[Cline, Melissa S.]
Lengauer, Thomas
Albrecht, Mario
2008Journal Article
Integrating the GO graph structure in scoring the
significance of Gene Ontology terms
Universität des Saarlandes
Alexa, Adrian2005Thesis - Masters thesis
Integrative computational biology
In: Integrative Biology [4], 713-714
Baumbach, Jan2012Journal Article
Integrative visual analysis of the effects of alternative splicing on protein domain interaction networks
In: Journal of Integrative Bioinformatics [5], 101-115
Emig, Dorothea
[Cline, Melissa S.]
[Klein, Karsten]
[Kunert, Anne]
[Mutzel, Petra]
Lengauer, Thomas
Albrecht, Mario
2008Journal Article
Intensive blood glucose control is safe and effective in diabetic cats using home monitoring and treatment with glargine
In: Journal of feline medicine and surgery [11], 668-682
Roomp, Kirsten
[Rand, Jacquie]
2009Journal Article
Inter-country mixing in HIV transmission clusters: a pan-European phylodynamics study
In: Abstract Book 11th European HIV & Hepatitis Workshop, 9
Kalaghatgi, Prabhav
Lawyer, Glenn
2013Poster
Attachment IconInter-individual variation of DNA methylation and its implications for large-scale epigenome mapping
In: Nucleic Acids Research [36], e55
Bock, Christoph
[Walter, Jörn]
[Paulsen, Martina]
Lengauer, Thomas
2008Journal Article
Interactive exploration of large genome and epigenome datasets in real time
In: Genome Biology [13], xx
Halachev, Konstantin
Bast, H.
Lengauer, Thomas
Bock, Christoph
2013Journal Article
Intragenic allele pyramiding combines different specificities of wheat Pm3 resistance alleles
In: The Plant Journal [64], 433-445
[Brunner, Susanne]
[Hurni, Severine]
[Streckeisen, Philipp]
Mayr, Gabriele
Albrecht, Mario
[Yahiaoui, Nabila]
[Keller, Beat]
2010Journal Article
Introduction
In: Bioinformatics - From Genomes to Therapies 1. The Building Blocks: Molecular Sequences and Structures, 1-24
Lengauer, ThomasLengauer, Thomas2007Part of a Book
Investigation of expert rule bases, logistic regression, and non-linear machine learning techniques for predicting response to antiretroviral treatment
In: Antiviral Therapy [14], 433-442
[Prosperi, Mattia C. F.]
Altmann, André
[Rosen-Zvi, Michal]
[Aharoni, Ehud]
[Gabor, Borgulya]
[Fulop, Bazso]
[Sonnerborg, Anders]
[Schulter, Eugen]
[Struck, Daniel]
[Ulivi, Giovanni]
[Vandamme, Anne-Mieke]
[Vercauteren, Jurgen]
[Zazzi, Maurizio]
2009Journal Article
Involvement of novel HIV-1 reverse transcriptase mutations in the regulation of resistance to nucleoside inhibitors
In: Journal of Virology [80], 7186-7198
[Svicher, Valentina]
Sing, Tobias
[Santoro, Maria Mercedes]
[Forbici, Federica]
[Rodriguez- Barrios, Fátima]
[Bertoli, Ada]
[Beerenwinkel, Niko]
[Bellocchi, Maria Concetta]
[Gago, Federigo]
[d´Arminio Monforte, Antonella]
[Antinori, Andrea]
Lengauer, Thomas
Ceccherini-Silberstein, Francesca
[Perno, Carlo-Federico]
2006Journal Article
Attachment IconIRECS: A new algorithm for the selection of most probable ensembles of side-chain conformations in protein models.
In: Protein Science [16], 1294-1307
Hartmann, Christoph
Antes, Iris
Lengauer, Thomas
2007Journal Article
Iterative Subgraph Mining for Principal Component Analysis.
In: Proceedings of the IEEE International Conference on Data Mining (ICDM2008), DM934
Saigo, Hiroto
[Tsuda, Koji]
[Giannotti, Fosca]
[Gunopulos, Dimitrios]
2008Proceedings Article
IVF: stars may have to consider the risk of stolen parenthood
In: Nature [454], 938
Bock, Christoph2008Journal Article
Ketoamide Resistance and Hepatitis C Virus Fitness in Val55 Variants
of the NS3 Serine Protease
In: Antimicrobial Agents and Chemotherapy [56], 1907-1915
Welsch, Christoph
[Schweizer, Sabine]
[Shimakami, Testsuro]
[Domingues, Francisco S.]
[Kim, Seungtaek]
[Lemon, Stanley, M.]
[Antes, Iris]
2012Journal Article
KeyPathwayMiner - Detecting case-specific biological pathways by using expression data
In: Internet Mathematics [7], 299-313
Alcaraz, Nicolas
Kucuk, Hande
[Weile, Jochen]
[Wipat, Anil]
Baumbach, Jan
2012Journal Article
Lactam hydrolysis catalyzed by mononuclear metallo-beta-lactamases: a density functional study
In: Journal of Physical Chemistry / B [107], 2366-2375
[Olsen, Lars]
[Antony, Jens]
[Ryde, Ulf]
Adolph, Hans-Werner
[Hemmingsen, Lars]
2003Journal Article
Lead Identification by Virtual Screening
In: Bioinformatics - From Genomes to Therapies 2. Getting at the Inner Workings: Molecular Interactions, 651-704
Kämper, Andreas
[Rognan, Didier]
Lengauer, Thomas
Lengauer, Thomas2007Part of a Book
Attachment IconLearning from past treatments and their outcome improves prediction of In Vivo response to anti-HIV therapy
In: Statistical Applications in Genetics and Molecular Biology [10], 1-32
Saigo, Hiroto
Altmann, André
Bogojeska, Jasmina
Müller, Fabian
[Nowozin, Sebastian]
Lengauer, Thomas
2011Electronic Journal Article
Learning localized rule mixtures by maximizing the area under the ROC curve, with an application to the prediction of HIV-1 coreceptor usage
Universität Freiburg
Sing, Tobias2004Thesis - Masters thesis
Learning mixtures of localized rules by maximizing the area under the ROC curve
In: ROCAI-2004: 1st International Workshop on ROC Analysis in Artificial Intelligence, 89-96
Sing, Tobias
Beerenwinkel, Niko
Lengauer, Thomas
[Hernández-Orallo, José]
[Ferri, César]
[Lachiche, Nicolas]
[Falch, Peter A.]
2004Proceedings Article
Learning multiple evolutionary pathways from cross-sectional data
In: Journal of Computational Biology [12], 584-598
Beerenwinkel, Niko
Rahnenführer, Jörg
[Däumer, Martin]
[Hoffmann, Daniel]
[Kaiser, Rolf]
[Selbig, Joachim]
Lengauer, Thomas
2005Journal Article
Learning multiple evolutionary pathways from cross-sectional data
In: RECOMB 2004 : proceedings of the Eighth Annual International Conference on Research in Computational Molecular Biology, 36-44
Beerenwinkel, Niko
Rahnenführer, Jörg
Däumer, Martin
Hoffmann, Daniel
Kaiser, Rolf
Selbig, Joachim
Lengauer, Thomas
[Gusfield, Dan]
[Bourne, Philip]
[Istrail, Sorin]
[Pevzner, Pavel]
[Waterman, Michael]
2004Proceedings Article
Local and covariate-modulated false discovery rates applied in neuroimaging
In: NeuroImage [47], 213-219
[Lawyer, Glenn]
[Ferkingstad, Egil]
[Nesvåg, Rangan]
[Varnäs, Katarina]
[Agartz, Ingrid]
2009Journal Article
Attachment IconLocal function conservation in sequence and structure space
In: PLoS Computational Biology [4], e1000105
Weinhold, Nils
Sander, Oliver
Domingues, Francisco S.
Lengauer, Thomas
Sommer, Ingolf
2008Journal Article
Local protein structure prediction using discriminative models
In: BMC Bioinformatics [7], 1-13
Sander, Oliver
Sommer, Ingolf
Lengauer, Thomas
2006Electronic Journal Article
Local sequence-structure relationships in proteins
Friedrich-Alexander-Universität Erlangen-Nürnberg
Sander, Oliver2004Thesis - other
Attachment IconLow k-shells identify bridge elements critical to disease flow in small-world networks
In: Numerical Analysis and Applied Mathematics (ICNAAM 2012), 1426-1429
Reppas, Andreas
Lawyer, Glenn
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2012Proceedings Article
LRRK2 mutations and parkinsonism
In: The Lancet [365], 1230
Albrecht, Mario2005Journal Article
Lung stem cell self-renewal relies on BMI1-dependent control of expression at imprinted loci
In: Cell Stem Cell [9], 272-280
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[Ho, Joshua W. K.]
[Zamponi, Raffaella]
[Gazit, Roi]
Bock, Christoph
[Jäger, Natalie]
[Smith, Zachary D.]
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[Wong, Janice]
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[Roach, Rebecca R.]
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[Gimelbrant, Alexander A.]
[Park, Peter J.]
[Kim, Carla F.]
2011Journal Article
Managing drug resistance in cancer: lessons from HIV therapy
In: Nature Reviews Cancer [12], 494-501
Bock, Christoph
Lengauer, Thomas
2012Journal Article
Managing drug resistance in cancer: lessons from HIV therapy
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Lengauer, Thomas
Bock, Christoph
2012Journal Article
Attachment IconMAP Kinase Docking Motifs in HIV Proteins
Universität des Saarlandes
Bastys, Tomas2012Thesis - Masters thesis
Maximal Common Subgraph DAGs: Theory and Application to Virtual Screening in Drug Development
Universität des Saarlandes
Kunert, Lars2011Thesis - PhD thesis
Measuring and analyzing tissue specificity of human genes and protein complexes
In: EURASIP Journal on Bioinformatics and Systems Biology [2011], 5,1-5,6
Emig, Dorothea
Kacprowski, Tim
Albrecht, Mario
2011Journal Article
Measuring and analyzing tissue specificity of human genes and protein complexes
In: Seventh International Workshop on Computational Systems
Biology, WCSB 2010, 27-30
Emig, Dorothea
Kacprowski, Tim
Albrecht, Mario
[Nykter, Matti]
[Ruusuvuori, Pekka]
[Carlberg, Carsten]
[Yli-Harja, Olli]
2010Proceedings Article
Metabolic high- content screening of Saccharomyces cerevisiae reveals superior performance of single gene deletion strains
In: Process Biochemistry [41], 2170-2179
[Velagapudi, Vidya R.]
[Wittmann, Christoph]
Lengauer, Thomas
Talwar, Priti
[Heinzle, Elmar]
2006Journal Article
MethMarker – A toolkit for design, optimization and validation of DNA methylation biomarkers for cancer diagnosis and therapy optimization
Universität des Saarlandes
Schüffler, Peter2008Thesis - Masters thesis
Attachment IconMethMarker: User-friendly design and optimization of gene-specific DNA methylation assays
In: Genome Biology [10], R105:1-R105:10
Schüffler, Peter
[Mikeska, Thomas]
[Waha, Andreas]
Lengauer, Thomas
Bock, Christoph
2009Journal Article
Methoden zur Interpretation genotypischer Resistenztests
In: Resistenz in der HIV-Therapie : Diagnostik und Management, 66-68
Beerenwinkel, Niko[Oette, Mark]
[Kaiser, Rolf]
[Häussinger, Dieter]
2004Part of a Book
Methods for optimizing antiviral combination therapies
In: Bioinformatics [19], i16-i25
Beerenwinkel, Niko
Lengauer, Thomas
[Däumer, Martin]
[Kaiser, Rolf]
[Walter, Hauke]
[Korn, Klaus]
[Hoffmann, Daniel]
[Selbig, Joachim]
2003Journal Article
Microarrays: How many do you need?
In: Journal of Computational Biology [10], 653-667
[Zien, Alexander]
[Fluck, Juliane]
[Zimmer, Ralf]
Lengauer, Thomas
2003Journal Article
Microarrays: How Many Do You Need?
In: Proceedings of the Sixth Annual Conference on Research in Computational Molecular Biology (RECOMB2002), 321-330
[Zien, Alexander]
[Fluck, Juliane]
[Zimmer, Ralf]
Lengauer, Thomas
[Myers, Gene]
[Hannenhalli, Sridhar]
[Istrail, Sorin]
[Pevzner, Pavel]
[Waterman, Michael]
2002Proceedings Article
MicroRNA Transcription Start Site Prediction with Multi-objective Feature Selection
In: Statistical Applications in Genetics and Molecular Biology [11], 6.1-6.25
[Bhattacharyya, Malay]
Feuerbach, Lars
[Bhadra, Tapas]
[Bandyopadhyay, Sanghamitra]
2012Journal Article
MIMA - A software for analyte identification in MCC/IMS chromatograms by mapping accompanying GC/MS measurements
In: International Journal for Ion Mobility Spectrometry [?], ?
[Maurer, Felix]
Hauschild, Anne-Christin
[Eisinger, Kathrin]
Baumbach, Jan
[Mayor, Arno]
[Baumbach, Jörg Ingo]
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Mining GO annotations for improving annotation consistency
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[Faria, Daniel]
Schlicker, Andreas
[Pesquita, Catia]
[Bastos, Hugo]
[Ferreira, António E N]
Albrecht, Mario
[Falcão, André O]
2012Electronic Journal Article
Model-Based Anti HIV Therapy
Universität des Saarlandes
Sing, Tobias2008Thesis - PhD thesis
Attachment IconModel Selection for Mixtures of Mutagenetic Trees
In: Statistical Applications in Genetics and Molecular Biology [5], Article 17
[Yin, Junming]
[Beerenwinkel, Niko]
Rahnenführer, Jörg
Lengauer, Thomas
2006Journal Article
Model Selection for Mixtures of Mutagenetic Trees
Universität des Saarlandes
Yin, Junming2005Thesis - Masters thesis
Modeling HIV Neutralization
Universität des Saarlandes
Hauschild, Anne-Christin2011Thesis - Masters thesis
Modeling influenza evolution in response to immune system pressure
Universität des Saarlandes
Eldarov, Nasimi2012Thesis - Masters thesis
Modeling of Flexible Side Chains for Protein-Ligand Docking
Universität des Saarlandes
Hartmann, Christoph2008Thesis - PhD thesis
Modelling amorphous Si3B3N7: Structure and elastic properties
In: Physical Review [B 70], 144201-144201
[Hannemann, A.]
[Schön, J.C.]
[Jansen, M.]
[Putz, H.]
Lengauer, Thomas
2004Journal Article
Modelling binding between CCR5 and CXCR4 receptors and their ligands suggests the surface electrostatic potential of the co-receptor to be a key player in the HIV-1 tropism
In: Retrovirology [10], 130
Kalinina, Olga
Pfeifer, Nico
Lengauer, Thomas
2013Journal Article
Attachment IconMolecular basis of telaprevir resistance due to V36 and T54 mutations in the NS3-4A protease of HCV
In: Genome Biology [9], R16
[Welsch, Christoph]
Domingues, Francisco S.
[Susser, Simone]
Antes, Iris
Hartmann, Christoph
Mayr, Gabriele
Schlicker, Andreas
[Sarrazin, Christoph]
Albrecht, Mario
[Zeuzem, Stefan]
Lengauer, Thomas
2008Journal Article
Molecular Dynamics and Free Energy Studies on the Wild-Type and Mutated HIV-1
Protease Complexed with Four Approved Drugs: Mechanism of Binding and
In: Journal of Chemical Information and Modeling [49], 1751-1761
[Alcaro, Stefano]
[Artese, Anna]
[Ceccherini-Silberstein, Francesca]
[Ortuso, Francesca]
[Perno, Carlo Federico]
Sing, Tobias
[Svicher, Valentina]
2009Journal Article
Molecular Dynamics based prediction of HIV-1 drug resistance
Universität des Saarlandes
Djoumbou, Yannick2008Thesis - Masters thesis
Molecular dynamics simulations of photoactive yellow protein (PYP) in three states of its photocycle: a comparison with X-ray and NMR data and analysis of the effects of Glu46 deprotonation and mutation
In: European Biophysics Jounal [31], 504-520
Antes, Iris
[Thiel, Walter]
[Gunsteren van, Wilfred F.]
2002Journal Article
Moment invariants as shape recognition technique for comparing protein binding sites
In: Bioinformatics [23], 3139-3146
Sommer, Ingolf
Müller, Oliver
Domingues, Francisco S.
Sander, Oliver
[Weickert, Joachim]
Lengauer, Thomas
2007Journal Article
Attachment IconMotif Search in Protein Sequences for Protein
Structure Prediction
Universität des Saarlandes
Krier, Markus2005Thesis - Bachelor thesis
Mtreemix: a software package for learning and using mixture models of mutagenetic trees
In: Bioinformatics [21], 2106-2107
Beerenwinkel, Niko
Rahnenführer, Jörg
[Kaiser, Rolf]
[Hoffmann, Daniel]
[Selbig, Joachim]
Lengauer, Thomas
2005Journal Article
Multi-scale computational modeling of developmental biology
In: Bioinformatics [28], 2022-2028
Setty, Yaki2012Journal Article
Attachment IconMulti-Task Learning for HIV Therapy Screening
In: Proceedings, Twenty-Fifth International Conference on Machine Learning, 56-63
Bickel, Steffen
Bogojeska, Jasmina
Lengauer, Thomas
Sheffer, Tobias
[McCallum, Andrew]
[Roweis, Sam]
2008Proceedings Article
Multiple-Ligand-Based Virtual Screening: Methods and Applications of the MTree Approach
In: Journal of Medicinal Chemistry [48], 6575-6584
[Hessler, G.]
[Zimmermann, M.]
[Matter, H.]
[Evers, A.]
[Naumann, T.]
Lengauer, Thomas
[Rarey, M.]
2005Journal Article
Multivariate permutation tests for the k-sample problem with clustered data
In: Computational Statistics [17], 165-184
Rahnenführer, Jörg2002Journal Article
Attachment IconMutagenetic tree Fisher kernel improves prediction of HIV drug resistance from viral genotype
In: Advances in Neural Information Processing Systems 19, 1-9
Sing, Tobias
[Beerenwinkel, Niko]
[Schölkopf, B]
[Platt, J.]
[Hoffman, T.]
2007Proceedings Article
Mutations in ABC1 in Tangier disease and familial high-density lipoprotein
In: Nature Genetics [22], 336-45
[Brooks-Wilson, A]
[Marcil, Michel]
[Clee, Susanne M.]
[Zhang, Lin-Hua]
Roomp, Kirsten
[van Dam, M]
[Yu, L]
[Brewer, C]
[Collins, Jennifer A.]
[Molhuizen, H.O.]
[Loubser, O]
[Ouelette, B.F.]
[Fichter, K]
[Ashbourne-Excoffon, K.J.]
[Sensen, C.W.]
[Scherer, S]
[Mott, S]
[Denis, M]
[Martindale, D]
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[Hayden, Michael R.]
1999Journal Article
Mutations in gp41 are correlated with coreceptor tropism but do not improve prediction methods substantially
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Thielen, Alexander
Lengauer, Thomas
[Swenson, Luke C]
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Mutations in the ABC1 gene in familial HDL deficiency with defective cholesterol efflux
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[Brooks-Wilson, A.]
[Clee, Susanne M.]
Roomp, Kirsten
[Zhang, Lin-Hua]
[Yu, L.]
[Collins, Jennifer A.]
[van Dam, M.]
[Molhuizen, H. O.]
[Loubser, O.]
[Ouelette, B. F.]
[Sensen, C. W.]
[Fichter, K.]
[Mott, S.]
[Denis, M.]
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[Kastelein, J. J. P.]
[Hayden, Michael R.]
1999Journal Article
Attachment IconMutations in the MutSalpha interaction interface of MLH1 can abolish DNA mismatch repair
In: Nucleic Acids Research [34], 6574-6586
[Plotz, Guido]
[Welsch, Christoph]
[Giron-Monzon, Luis]
[Friedhoff, Peter]
Albrecht, Mario
[Piiper, Albrecht]
Biondi, Ricardo M.
Lengauer, Thomas
[Zeuzem, Stefan]
[Raedle, Jochen]
2006Journal Article
Mutations in the NB-ARC domain of I-2 that impair ATP hydrolysis cause autoactivation
In: Plant Physiology [140], 1233-1245
[Tameling, Wladimir I.]
[Vossen, Jack H.]
Albrecht, Mario
Lengauer, Thomas
[Berden, Jan A.]
[Haring, Michel A.]
[Cornelissen, Ben J.C.]
Takken, Frank L. W.
2006Journal Article
Mutations within GP41 are correlated with coreceptor tropism but do not substantially improve coreceptor usage prediction
In: Reviews in Antiviral Therapy & Infectious Diseases, 47-47
Thielen, Alexander
Lengauer, Thomas
[Harrigan, P Richard]
[Swenson, Luke]
[Dong, Winnie WY]
[McGovern, Rachel A]
[Lewis, Marilyn]
[James, Ian]
[Heera, Jayvant]
[Valdez, Hernan]
2010Poster
Network analysis of viral host factors
Universität des Saarlandes
Speicher, Nora K.2010Thesis - Bachelor thesis
Attachment IconNetworkPrioritizer: a versatile tool for network-based prioritization of candidate disease genes or other molecules
In: Bioinformatics [29], 1471-1473
Kacprowski, Tim
Doncheva, Nadezhda T.
Albrecht, Mario
2013Journal Article
Neue Wege zur Optimierung von Anti-HIV Therapien
In: BIOforum [24], 912-914
Beerenwinkel, Niko
[Däumer, Martin]
[Hoffmann, Daniel]
[Kaiser, Rolf]
[Korn, Klaus]
Lengauer, Thomas
[Schmidt, Barbara]
[Walter, Hauke]
[Selbig, Joachim]
2001Journal Article
New inhibitors of human cathepsin G identified by surface display library screening and peptide-protein docking
In: 7th International Symposium on Pharmaceutical Sciences (ISOPS-7), 46-49
[Jose, Joachim]
[Betschieder, Dirk]
Ray, Somak
Lengauer, Thomas
[Zangen, D]
2003Proceedings Article
Novel Aldosterone Synthase Inhibitors with Extended Carbocyclic Skeleton by a Combined Ligand-Based and Structure-Based Drug Design Approach
In: Journal of Medical Chemistry [51], 6138-6149
[Lucas, Simon]
[Heim, Ralph]
[Negri, Matthias]
Antes, Iris
[Ries, Christina]
[Schewe, Katarzyna E.]
[Bisi, Alessandra]
[Gobbi, Silvia]
[Hartmann, Rolf W.]
2008Journal Article
Novel analysis approaches to context-dependent molecular networks
Universität des Saarlandes
Emig, Dorothea2011Thesis - PhD thesis
Novel Approaches to the Integration and Analysis of Systems Biology
Universität des Saarlandes
Ramirez, Fidel2012Thesis - PhD thesis
Novel search method for the discovery of functional relationships
In: Bioinformatics [28], 269-276
Ramírez, Fidel
Lawyer, Glenn
Albrecht, Mario
2012Journal Article
Novel Sm-like proteins with long C-terminal tails and associated methyltransferases
In: FEBS Letters [569], 18-26
Albrecht, Mario
Lengauer, Thomas
2004Journal Article
Novel technologies for virtual screening
In: Drug Discovery Today [9], 27-34
Lengauer, Thomas
[Lemmen, Christian]
[Rarey, Matthias]
[Zimmermann, M.]
2004Journal Article
NOXclass: prediction of protein-protein interaction types
In: BMC Bioinformatics [7], 1-15
Zhu, Hongbo
Domingues, Francisco S.
Sommer, Ingolf
Lengauer, Thomas
2006Electronic Journal Article
On open problems in biological network visualization
In: Graph Drawing : 17th International Symposium, GD 2009, 256-267
Albrecht, Mario
[Kerren, Andreas]
[Klein, Karsten]
[Kohlbacher, Oliver]
[Mutzel, Petra]
[Paul, Wolfgang]
[Schreiber, Falk]
[Wybrow, Michael]
[Eppstein, David]
[Gansner, Emden R.]
2010Proceedings Article
On preferences of general two-sided tests with applications to Kolmogorov-Smirnov-type tests
In: Statistics & Decisions [21], 115-136
Rahnenführer, Jörg2003Journal Article
On the Applicability of Elastic Network Normal Modes in Small-Molecule Docking
In: Journal of Chemical Information and Modeling [52], 844-856
Dietzen, Matthias
Zotenko, Elena
[Hildebrandt, Andreas]
Lengauer, Thomas
2012Journal Article
On the importance of statistics in breath analysis - Hope or curse?[Eckel, Sandrah]
Baumbach, Jan
Hauschild, Anne-Christin
2014Unpublished/Draft
On the power and limits of evolutionary conservation - unraveling bacterial gene regulatory networks
In: Nucleic Acids Research [38], 7877-7884
Baumbach, Jan2010Journal Article
On the predictability of CpG methylation in human tissue at single basepair resolution
Universität des Saarlandes
Glaab, Enrico2006Thesis - Bachelor thesis
On the trail of EHEC/EAEC - unraveling the gene regulatory networks of human pathogenic Escherichia coli bacteria
In: Integrative Biology [4], 728-733
Pauling, Josch
Röttger, Richard
[Neuner, Andreas]
[Salgado, Heladia]
[Collado-Vides, Julio]
Kalaghatgi, Prabhav
[Azevedo, Vasco]
[Tauch, Andreas]
[Pühler, Alfred]
Baumbach, Jan
2012Journal Article
Online Transitivity Clustering of Biological Data with Missing Values
In: German Conference on Bioinformatics 2012 (GCB 2012), 57-68
Röttger, Richard
Kreutzer, Christoph
[Duong Vu, Thuy]
[Wittkop, Tobias]
Baumbach, Jan
[Böcker, Sebastian]
[Hufsky, Franziska]
[Scheubert, Kerstin]
[Schleicher, Jana]
[Schuster, Stefan]
2012Electronic Proceedings Article
Only Slight Impact of Predicted Replicative Capacity for Therapy Response Prediction
In: PLoSOne [5], e9044,1-e9044,10
Weisser, Hendrik
Altmann, André
[Sierra, Saleta]
[Incardona, Francesca]
[Struck, Daniel]
[Sönnerborg, Anders]
[Kaiser, Rolf]
[Zazzi, Maurizio]
[Tschochner, Monika]
[Walter, Hauke]
Lengauer, Thomas
2010Electronic Journal Article
Attachment IconOntology-based Similarity Measures and their Application in Bioinformatics
Universität des Saarlandes
Schlicker, Andreas2010Thesis - PhD thesis
Optimisation of baseline genotypic testing for safe and efficient maraviroc administration
In: Journal of the International AIDS Society, 101-102
[Sierra, Saleta]
[Dzbowski, Jan Nikolaj]
Pironti, Alejandro
[Gueney, L]
Thielen, Alexander
[Reuter, Stefan]
[Esser, Stefan]
[Fätkenheuer, Gerd]
Lengauer, Thomas
[Hider, Dominik]
[Hoffmann, Daniel]
[Pfister, Holger]
[Jensen, Björn]
[Kaiser, Rolf]
[Kippax, Susan]
[Salif Sow, Papa]
[Wainberg, Mark]
[Heidari, Shirin]
2012Poster
Attachment IconOptimization of Quantitative MGMT Promoter Methylation Analysis Using Pyrosequencing and Combined Bisulfite Restriction Analysis
In: Journal of Molecular Diagnostics [9], 368-381
[Mikeska, Thomas]
Bock, Christoph
[El-Maarri, Osman]
[Hübner, Anika]
[Ehrentraut, Denise]
[Schramm, Johannes]
[Felsberg, Jörg]
[Kahl, Philip]
[Büttner, Reinhard]
[Pietsch, Torsten]
[Waha, Andreas]
2007Journal Article
Parallel "go with the winners algorithms" in Distributed Memory Models
In: Journal of Parallel and Distributed Processing [63], 801-814
[Peinado, M.]
Lengauer, Thomas
2003Journal Article
Partitioning biological data with transitivity clustering
In: Nature Methods [7], 419-420
[Wittkop, Tobias]
Emig, Dorothea
[Lange, Sita]
[Rahmann, Sven]
Albrecht, Mario
[Morris, John H.]
[Böcker, Sebastian]
[Stoye, Jens]
Baumbach, Jan
2010Journal Article
Attachment IconPatients with high grade gliomas harboring delections of chromosomes 9p and 10q benefit from temozolomide treatment
In: Neoplasia [7], 883-893
[Wemmert, Silke]
[Ketter, Ralf]
Rahnenführer, Jörg
Beerenwinkel, Niko
[Strowitzki, Martin]
[Feiden, Wolfgang]
[Hartmann, Christian]
Lengauer, Thomas
[Stockhammer, Florian]
[Zang, Klaus D.]
[Meese, Eckart]
[Steudel, Wolf-Ingo]
[von Deimling, Andreas]
[Urbschat, Steffi]
2005Journal Article
Paving the future: finding suitable ISMB venues
In: Bioinformatics [28], 2556-2559
[Rost, Burkhard]
[Gaasterland, Terry]
Lengauer, Thomas
[Linial, Michal]
[Markel, Scott]
[McKay, B. J. Morrison]
[Schneider, Reinhard]
[Horton, Paul]
[Kelso, Janet]
2012Journal Article
Attachment IconPaving the Way for Automated Clinical Breath Analysis and Biomarker DetectionHauschild, Anne-Christin
[Baumbach, Joerg Ingo]
Baumbach, Jan
2013Miscellaneous
Peak Detection Method Evaluation for Ion Mobility Spectrometry by using Machine Learning Approaches
In: Metabolites [3], 277-293
Hauschild, Anne-Christin
[Kopczynski, Dominik]
[D'Addario, Marianna]
[Baumbach, Joerg Ingo]
[Rahmann, Sven]
Baumbach, Jan
2013Electronic Journal Article
Peptidomimetic Escape Mechanisms Arise via Genetic Diversity in the Ligand-Binding Site of the Hepatitis C Virus NS3/4A Serine Protease
In: Gastroenterology [142], 654-663
[Welsch, Christoph]
[Shimakami, Tetsuro]
[Hartmann, Christoph]
[Yang, Yan]
[Domingues, Francisco S.]
Lengauer, Thomas
[Zeuzem, Stefan]
[Lemon, Stanley M.]
2012Journal Article
Performance of genotypic coreceptor measurement using geno2pheno[coreceptor] in B- and non-B HIV subtypes in a large cohort of therapy-experienced patients in Germany
In: Reviews in Antiviral Therapy, 99-99
Thielen, Alexander
[Sichtig, Nadine]
[Braun, Patrick]
[Däumer, Martin]
[Walter, Hauke]
[Noah, Christian]
[Wolf, Eva]
[Müller, Harm]
[Stürmer, Martin]
Lengauer, Thomas
[Kaiser, Rolf]
[Obermeier, Martin]
2009Poster
Permutation importance: an unbiased feature importance measure
In: Bioinformatics [26], 1340-1347
Altmann, André
Tolosi, Laura
Sander, Oliver
Lengauer, Thomas
2010Journal Article
PIPS: Pathogenicity Island Prediction Software
In: PLoS One [7], e30848,1-e30848,10
[Soares, Siomar C.]
[Abreu, Vinícius A. C.]
[Ramos, Rommel T. J.]
[Cerdeira, Louise]
[Silva, Artur]
Baumbach, Jan
[Trost, Eva]
[Tauch, Andreas]
[Hirata, Raphael]
[Mattos-Guaraldi, Ana L.]
[Miyoshi, Anderson]
[Azevedo, Vasco]
2012Electronic Journal Article
POEM: Parameter Optimization using Ensemble Methods: Application to target specific scoring functions
In: Journal of Chemical Information and Modeling [45], 1291-1302
Antes, Iris
Merkwirth, Christian
Lengauer, Thomas
2005Journal Article
Population-based V3 genotypic tropism assay: a retrospective analysis using screening samples from the A4001029 and MOTIVATE studies
In: AIDS [24], 2517-2525
[McGovern, Rachel A]
Thielen, Alexander
[Mo, Theresa]
[Dong, Winnie]
[Woods, Conan K]
[Chapman, Douglass]
[Lewis, Marilyn]
[James, Ian]
[Heera, Jayvant]
[Valdez, Hernan]
[Harrigan, P Richard]
2010Journal Article
Positive selection of HIV host factors and the evolution of lentivirus genes
In: BMC Evolutionary Biology [10], 186,1-186,15
Bozek, Katarzyna
Lengauer, Thomas
2010Electronic Journal Article
Predicting drug susceptibility of non-small cell lung cancers based on genetic lesions
In: Journal of Clinical Investigation [119], 1727-1740
[Sos, Martin L.]
[Michel, Kathrin]
[Zander, Thomas]
[Weiss, Jonathan]
[Frommolt, Peter]
[Pfeifer, Martin]
[Li, Danan]
[Ullrich, Roland]
[Koker, Mirjam]
[Fischer, Florian]
[Shimamura, Takeshi]
[Rauh, Daniel]
[Mermel, Craig]
[Fischer, Stefanie]
[Stückrath, Isabel]
[Heynck, Stefanie]
[Beroukhim, Rameen]
[Lin, William]
[Winckler, Wendy]
[Shah, Kinjal]
[LaFramboise, Thomas]
[Moriarty, Whei F.]
Hanna, megan
Tolosi, Laura
[Rahnenführer, Jörg]
[Verhaak, Roel]
[Chiang, Derek]
[Getz, Gad]
[Hellmich, Martin]
[Wolf, Jürgen]
[Girard, Luc]
[Peyton, Michael]
[Weir, Barbara A.]
[Chen, Tzu-Hsiu]
[Greulich, Heidi]
[Barretina, Jordi]
[Shapiro, Geoffrey I.]
[Garraway, Levi A.]
[Gazdar, Adi F.]
[Minna, John D.]
[Meyerson, Matthew]
[Wong, Kwok-Kin]
[Thomas, Roman K.]
2009Journal Article
Predicting HIV coreceptor usage on the basis of genetic and clinical covariates
In: Antiviral Therapy [12], 1097-1106
Sing, Tobias
Low, Andrew J.
Beerenwinkel, Niko
Sander, Oliver
[Cheung, Peter K.]
Domingues, Francisco S.
Büch, Joachim
[Däumer, Martin]
[Kaiser, Rolf]
Lengauer, Thomas
[Harrigan, P. Richard]
2007Journal Article
Predicting interactions between T cell receptors and MHC-peptide complexes
In: Molecular Immunology [48], 553-562
Roomp, Kirsten
Domingues, Francisco S.
2011Journal Article
Predicting MHC class I epitopes in large datasets
In: BMC Bioinformatics [11], 90,1-90,11
Roomp, Kirsten
Antes, Iris
Lengauer, Thomas
2010Electronic Journal Article
Predicting Protein Structure Classes from Function Predictions
In: Bioinformatics [20], 770-776
Sommer, Ingolf
Rahnenführer, Jörg
Domingues, Francisco S.
[de Lichtenberg, Ulrik]
Lengauer, Thomas
2004Journal Article
Predicting Response to Antiretroviral Treatment by Machine Learning:
The EuResist Project
In: Intervirology [55], 123-127
[Zazzi, Maurizio]
[Incardona, Francesca]
[Rosen-Zvi, Michal]
[Prosperi, Mattia]
Lengauer, Thomas
Altmann, Andre
[Sonnerborg, Anders]
[Lavee, Tamar]
[Schülter, Eugen]
[Kaiser, Rolf]
2012Journal Article
Predicting the Response to Combination Antiretroviral Therapy: Retrospective Validation of
geno2pheno-THEO on a Large Clinical Database
In: The Journal of Infectious Diseases [199], 999-1006
Altmann, André
[Däumer, Martin]
[Beerenwinkel, Niko]
[Peres, Yardena]
[Schülter, Eugen]
Büch, Joachim
[Rhee, Soo-Yon]
[Sönnerborg, Anders]
[Fessel, W. Jeffrey]
[Shafer, Robert W.]
[Zazzi, Maurizio]
[Kaiser, Rolf]
Lengauer, Thomas
2009Journal Article
Prediction of Domain and Motif Interactions from Protein Networks
Universität des Saarlandes
Schelhorn, Sven-Eric2007Thesis - Masters thesis
Prediction of HIV-1 coreceptor usage (tropism) by sequence analysis using a genotypic approach
In: Journal of Visualized Experiments [58], e3264,1-e3264,9
[Sierra, Saleta]
[Kaiser, Rolf]
[Lübke, Nadine]
Thielen, Alexander
[Schuelter, Eugen]
[Heger, Eva]
[Däumer, Martin]
[Reuter, Stefan]
[Esser, Stefan]
[Fätkenheuer, Gerd]
[Pfister, Herbert]
[Oette, Mark]
Lengauer, Thomas
2011Electronic Journal Article
Prediction of linear B-cell epitopes and MHC class II binding peptides
Eberhardt-Karls-Universität Tübingen
Thielen, Alexander2006Thesis - Masters thesis
Prediction of percutaneous drug absorption
In: Journal of Chemical Information and Modeling [1], 424-429
[Neumann, Dirk]
[Kohlbacher, Oliver]
[Merkwirth, Christian]
Lengauer, Thomas
2006Journal Article
Prediction of Response to Antiretroviral Therapy by Human Experts and by the EuResist Data-Driven Expert System (the EVE study)
In: HIV Medicine [12], 211-218
[Zazzi, M.]
[Kaiser, R.]
[Sönnerborg, A.]
[Struck, D]
Altmann, Andre
[Prosperi, M.]
[Rosen-Zvi, M.]
[Petroczi, A.]
[Peres, Y.]
[Schülter, E.]
[Boucher, C.A.]
[Brun-Vezinet, F.]
[Harrigan, R.]
[Morris, L.]
[Obermeier, M.]
[Perno, C.-F.]
[Phanuphak, P.]
[Pillay, D]
[Shafer, R.W.]
[Vandamme, A.-M.]
[Van Laethem, K.]
[Wensing, A.]
Lengauer, Thomas
[Incardona, F.]
2011Journal Article
Prediction of Response to Antiretroviral Therapy by Human Experts and by the EuResist Data-Driven Expert System (the EVE Study)
In: HIV Medicine [Early View], 1-8
[Zazzi, Maurizio]
[Kaiser, Rolf]
[Sönnerborg, Anders]
[Struck, Daniel]
Altmann, Andre
[Prosperi, Mattia C. F.]
[Rosen-Zvi, Michal]
[Petroczi, Andrea]
[Peres, Yardena]
[Schülter, Eugen]
[Boucher, Charles]
[Brun-Vezinet, Francoise]
[Harigan, Richard]
[Morris, Lynn]
[Obermeier, Martin]
[Perno, Federico]
[Shafer, Robert]
[Vandamme, Anne-Mieke]
[van Laethem, Kristel]
[Wensing, Annemarie]
Lengauer, Thomas
[Incardona, Francesca]
2010Electronic Journal Article
Prediction of Thermostability from Amino Acid Attributes by Combination of Clustering with Attribute Weighting: A New Vista in Engineering Enzymes
In: PLoS One [6], e23146,1-e23146,11
[Ebrahimi, Mansou]
[Lakizadeh, Amir]
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Ebrahimi, Mahdi
2011Electronic Journal Article
Preface: Special RECOMB 2001 Issue
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Lengauer, Thomas2002Journal Article
Preparation of reduced representation bisulfite sequencing libraries for genome-scale DNA methylation profiling
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Bock, Christoph
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2011Journal Article
Prevalence and characteristics of hepatitis B and C virus infections in treatment-naïve HIV-infected patients
In: Medical Microbiology and Immunology [200], 39-49
[Reuter, Stefan]
[Oette, Mark]
[Wilhelm, Frank Clemens]
Beggel, Bastian
[Kaiser, Rolf]
[Balduin, Melanie]
[Schweitzer, Finja]
[Verheyen, Jens]
[Adams, Ortwin]
Lengauer, Thomas
[Faetkenheuer, Gerd]
[Pfister, Herbert]
[Haeussinger, Dieter]
2011Journal Article
Probabilistic disease gene prioritization
Universität des Saarlandes
Pironti, Alejandro2009Thesis - Masters thesis
Probabilistic error correction for RNA sequencing
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Schulz, Marcel Holger
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Proceedings of the 5th Annual Conference on Research in Computational Molecular Biology (RECOMB2001)Lengauer, Thomas
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[Istrail, P.]
[Pevzner, P.]
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Proceedings of the European Conference on Computational Biology (ECCB 2002)Lengauer, Thomas
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2002Proceedings
Proceedings Twelfth International Conference on Intelligent Systems for Molecular Biology/Third European Conference on Computional Biology 2004 (ISMB/ECCB 2004)[Thornton, J.]
[Bourne, P.]
[Gilbert, D.]
[Goble, C.]
[Goldman, N.]
[Gribskov, M.]
[Hide, W.]
[Higgins, D.]
[Kanehisa, M.]
Lengauer, Thomas
[Linial, M.]
[Myers, G.]
[Quackenbush, J.]
[Rebholz-Schuhmann, D.]
[Rost, B.]
[Sowdhamini, R.]
[Valencia, A.]
[Vingron, M.]
[Xu, Y.]
2004Proceedings
Processing of high-throughput DNA methylation data
Universität des Saarlandes
Lutsik, Pavlo2010Thesis - Masters thesis
Profile-Profile Alignment: A Powerful Tool For Protein Structure Prediction
In: Pacific Symposium on Biocomputing, PSB 2003, 252-263
[von Öhsen, Niklas]
Sommer, Ingolf
[Zimmer, Ralf]
2003Proceedings Article
Profiling of parkin-binding partners using tandem affinity purification
In: PLoS ONE [8], 1-17
[Zanon, Alessandra]
[Rakovic, Aleksandar]
[Blankenburg, Hagen]
Doncheva, Nadezhda T.
[Schwienbacher, Christine]
[Serafin, Alice]
Alexa, Adrian
[Weichenberger, Christian X.]
Albrecht, Mario
[Klein, Christine]
[Hicks, Andrew A.]
[Pramstaller, Peter P.]
[Domingues, Francisco S.]
[Pichler, Irene]
2013Journal Article
ProML - the Protein Markup Language for specification of protein sequences, structures and families
In: In Silico Biology [2], 313 - 324
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[Zimmer, Ralf]
Lengauer, Thomas
2002Journal Article
Protease Inhibitor-Resistant Hepatitis C Virus Mutants With Reduced Fitness From Impaired Production of Infectious Virus
In: Gastroenterology [140], 667-675
[Shimakami, Tetsuro]
Welsch, Christoph
[Yamane, Daisuke]
[McGivern, David R.]
[Yi, MinKyung]
[Zeuzem, Stefan]
[Lemon, Stanley M.]
2011Journal Article
Protein-protein interactions: analysis and prediction
In: Modern Genome Annotation - The Biosapiens Network, 353-410
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Albrecht, Mario
Blankenburg, Hagen
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[Hermjakob, Henning]
[Jensen, Lars J.]
[Juan, David A.]
Lengauer, Thomas
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[Valencia, Alfonso]
[Frishman, Dmitrij]
[Valencia, Alfonso]
2009Part of a Book
Protein Fold Recognition Based on Distant Homologs
In: Bioinformatics - From Genomes to Therapies 1. The Building Blocks: Molecular Sequences and Structures, 351-388
Sommer, IngolfLengauer, Thomas2007Part of a Book
Protein Function from Sequence and Structure Data
In: Applied Bioinformatics [2], 3-12
Domingues, Francisco S.
Lengauer, Thomas
2003Journal Article
Protein phosphatase and TRAIL receptor genes as new candidate tumor genes on chromosome 8p in prostate cancer
In: Cancer Genomics & Proteomics [5], 123-136
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[Hoffmann, Michele J.]
Alexa, Adrian
[Yamanaka, Masanori]
[Müller, Mirko]
[Jung, Volker]
[Rahnenführer, Jörg]
[Schulz, Wolfgang A.]
2008Journal Article
Protein Structure Prediction and Databases
In: Nature Encyclopedia of the Human Genome, 864-867
Domingues, Francisco S.
Lengauer, Thomas
Sommer, Ingolf
Cooper, David2004Part of a Book
Protein Surface Remeshing and Characterisation Using Morse-Smale Complexes
Universität des Saarlandes
Stöckel, Daniel2008Thesis - Bachelor thesis
PSICQUIC and PSISCORE: accessing and scoring molecular interactions
In: Nature Methods [8], 528-529
[Aranda, Bruno]
Blankenburg, Hagen
[Kerrien, Samuel]
[Brinkman, Fiona S.]
[Ceol, Arnaud]
[Chautard, Emilie]
[Dana, Jose M.]
[De Las Rivas, Javier]
[Dumousseau, Marine]
[Galeota, Eugenia]
[Gaulton, Anna]
[Goll, Johannes]
[Hancock, Robert E. W.]
[Isserlin, Ruth]
[Jimenez, Rafael C.]
[Kerssemakers, Jules]
[Khadake, Jyoti]
[Lynn, David J.]
[Michaut, Magali]
[O'Kelly, Gavin]
[Ono, Keiichiro]
[Orchard, Sandra]
[Prieto, Carlos]
[Razick, Sabry]
[Rigina, Olga]
[Salwinski, Lukasz]
[Simonovic, Milan]
[Velankar, Sameer]
[Winter, Andrew]
[Wu, Guanming]
[Bader, Gary D.]
[Cesareni, Gianni]
[Donaldson, Ian M.]
[Eisenberg, David]
[Kleywegt, Gerard J.]
[Overington, John]
[Ricard-Blum, Sylvie]
[Tyers, Mike]
Albrecht, Mario
[Hermjakob, Henning]
2011Journal Article
Pyranose oxidase identified as a member of the GMC oxidoreductase family
In: Bioinformatics [19], 1216-1220
Albrecht, Mario
Lengauer, Thomas
2003Journal Article
Attachment IconQuantitative comparison of genome-wide DNA methylation mapping technologies
In: Nature Biotechnology [28], 1106-1114
Bock, Christoph
[Tomazou, Eleni M.]
[Brinkman, Arie B.]
Müller, Fabian
[Simmer, Femke]
[Gu, Hongcang]
[Jäger, Natalie]
[Gnirke, Andreas]
[Stunnenberg, Hendrik G.]
[Meissner, Alexander]
2010Journal Article
Quantitative phenotype prediction by support vector machines
In: Proceedings from the 5th International Workshop on HIV Drug resistance & Treatment Strategies, 97
Beerenwinkel, Niko
Lengauer, Thomas
[Schmidt, Barbara]
[Walter, Hauke]
[Kaiser, Rolf]
[Hoffmann, Daniel]
[Korn, Klaus]
[Selbig, Joachim]
2002Proceedings Article
Random Combinatorial Structures and Randomized Search Heuristics
Universität des Saarlandes
Johannsen, Daniel2010Thesis - PhD thesis
Rapid hybrid de novo assembly of a microbial genome using only short reads: Corynebacterium pseudotuberculosis I19 as a case study
In: Journal of Microbiological Methods [86], 218-223
[Cerdeira, Louise Teixeira]
[Carneir, Aadriana Ribeiro]
[Ramos, Rommel Thiago Juca]
[de Almeida, Sintia Silva]
[D'Afonseca, Vivian]
[Schneider, Maria Paula Cruz]
Baumbach, Jan
[Tauch, Andreas]
[McCulloch, John Anthony]
[Azevedo, Vasco Ariston Carvalho]
[Silva, Aartur]
2011Journal Article
Reaction graph kernels predict EC numbers of unknown enzymatic reactions in plant secondary metabolism
In: BMC Bioinformatics [11], S31,1-S31,7
Saigo, Hiroto
[Hattori, Masahiro]
[Kashima, Hisashi]
[Tsuda, Koji]
2010Electronic Journal Article
Recco: recombination analysis using cost optimization
In: Bioinformatics [22], 1064-1071
Maydt, Jochen
Lengauer, Thomas
2006Journal Article
Recent approaches to the prioritization of candidate disease genes
In: Wiley Interdisciplinary Reviews: Systems Biology and Medicine [4], 429-442
Doncheva, Nadezhda T
Kacprowski, Tim
Albrecht, Mario
2012Journal Article
Reconstructing anecestral methylation states in phylogenetic trees
Universität des Saarlandes
Koser, Sandra2012Thesis - Masters thesis
Reconstructing dynamic microRNA-regulated interaction networks
In: Proceedings of the National Academy of Sciences of the United States [110], 15686–15691
Schulz, Marcel Holger
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[Kaminski, Naftali]
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Reconstructing the ancestral germline methylation state of young repeats
In: Molecular Biology and Evolution [28], 1777-1784
Feuerbach, Lars
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Lengauer, Thomas
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2011Journal Article
Recruitment and activation of a lipid kinase by hepatitis C virus NS5A is essential for integrity of the membranous replication compartment
In: Cell Host & Microbe [9], 32-45
[Reiss, Simon]
[Rebhan, Ilka]
[Backes, Perdita]
[Romero-Brey, Ines]
[Erfle, Holger]
[Matula, Petr]
[Kaderali, Lars]
[Poenisch, Marion]
Blankenburg, Hagen
[Hiet, Marie-Sophie]
[Longerich, Thomas]
Diehl, Sarah
Ramírez, Fidel
[Balla, Tamas]
[Rohr, Karl]
[Kaul, Artur]
[Bühler, Sandra]
[Pepperkok, Rainer]
Lengauer, Thomas
Albrecht, Mario
[Eils, Roland]
[Schirmacher, Peter]
[Lohmann, Volker]
[Bartenschlager, Ralf]
2011Journal Article
Reference Maps of Human ES and iPS Cell Variation Enable High-Throughput Characterization of Pluripotent Cell Lines
In: Cell [144], 439-452
Bock, Christoph
[Kiskinis, Evangelos]
[Verstappen, Griet]
[Gu, Hongcang]
[Boulting, Gabriella]
[Smith, Zachary D.]
[Ziller, Michael]
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[Meissner, Alexander]
2011Journal Article
Refinement of homology modeled protein structures for molecular docking
In: Proceedings of the 367. WE-Heraeus Seminar on Biomolecular Simulations, 1
Antes, Iris
Lengauer, Thomas
2006Poster
Regulation of clock-controlled genes in mammals.
In: PLoS One [4], e4882:1-e4882:12
Bozek, Kasia
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[Kielbasa, Szymon M.]
[Heine, Markus]
[Dame, Christof]
[Kramer, Achim]
[Herzel, Hanspeter]
2009Electronic Journal Article
Relevance of HIV gag cleavage site mutations in failures of protease inhibitor therapies
In: Antiviral Therapy, A53
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Altmann, Andre
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[Reuter, Stefan]
[Fätkenheuer, Gerd]
[Pfister, Herbert]
[Kaiser, Rolf]
2008Poster
Replication enhancing mutations of the Hepatitis C virus replicon: Prevalence and clinical significance in patients with chronic Hepatitis C
In: Journal of Infectious Diseases [192], 1710-1719
Lengauer, Thomas
Albrecht, Mario
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Welsch, Christoph
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[Zeuzem, S.]
2005Journal Article
Resistance proteins: molecular switches of plant defence
In: Current Opinion in Plant Biology [9], 383-390
Takken, Frank L. W.
Albrecht, Mario
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2006Journal Article
Resistenzbestimmung
In: MMW Fortschritte in der Medizin [151], 74-75
Lengauer, Thomas
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2009Journal Article
Retinal properties and potential of the adult mammalian ciliary epithelium stem cells
In: Vision Research [45], 1653-1666
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Rahnenführer, Jörg
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[Zhao, Xing]
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2005Journal Article
RhizoRegNet - A database of rhizobial transcription factors and regulatory networks.
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[Goesmann, Alexander]
Baumbach, Jan
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2011Journal Article
Risk factors associated with older age in treatment-naive HIV-positive patients
In: Intervirology [55], 147-153
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[Oette, Mark]
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Lengauer, Thomas
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[Rockstroh, Jürgen]
[Knechten, Heribert]
[Häussinger, Dieter]
2012Journal Article
ROCR: Visualizing classifier performance in R
In: Bioinformatics [21], 3940-3941
Sing, Tobias
Sander, Oliver
Beerenwinkel, Niko
Lengauer, Thomas
2006Journal Article
Role of hepatitis B virus genetic barrier in drug-resistance and immune-escape development
In: Digestive and Liver Disease [43], 975-983
[Svicher, Valentina]
[Cento, Valeria]
[Salpini, Romina]
[Mercurio, Fabio]
[Fraune, Maria]
Beggel, Bastian
[Han, Yue]
[Gori, Caterina]
[Wittkop, Linda]
[Bertoli, Ada]
[Micheli, Valeria]
[Gubertini, Guido]
[Longo, Roberta]
[Romano, Sara]
[Visca, Michela]
[Gallinaro, Valentina]
[Marino, Nicoletta]
[Mazzotta, Francesco]
[De Sanctis, Giuseppe Maria]
[Fleury, Hervè]
[Trimoulet, Pascale]
[Angelico, Mario]
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[Zhang, Xin Xin]
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2011Journal Article
Role of hepatitis B virus genetic barrier in drug-resistance and immune-escape development
In: Digestive and Liver Disease [43], 975–983
[Svichera, Valentina]
[Centoa, Valeria]
[Salpinia, Romina]
[Mercurioa, Fabio]
[Fraune, Maria]
Beggel, Bastian
[Hanc, Yue]
[Gorid, Caterina]
[Wittkope, Linda]
[Bertolif, Ada]
[Michelig, Valeria]
[Gubertinig, Guido]
[Longoh, Roberta]
[Romanoh, Sara]
[Viscah, Michela]
[Gallinaroi, Valentina]
[Marinoj, Nicoletta]
[Mazzottaj, Francesco]
[De Sanctisi, Giuseppe Maria]
[Fleurye, Hervè]
[Trimoulete, Pascale]
[Angelicoa, Mario]
[Cappielloh, Giuseppina]
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[Pernoa, Carlo Federico]
2011Journal Article
RRBSMAP: a fast, accurate and user-friendly alignment tool for reduced representation bisulfite sequencing
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Bock, Christoph
Müller, Fabian
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2012Journal Article
RRBSMAP: A Fast, Accurate and User-friendly Alignment Tool for Reduced Representation Bisulfite Sequencing
In: Bioinformatics [28], 430-432
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Bock, Christoph
Müller, Fabian
[Sun, Deqiang]
[Meissner, Alexander]
[Li, Wei]
2011Journal Article
Attachment IconRtreemix: an R package for estimating evolutionary pathways and genetic progression scores
In: Bioinformatics [24], 2391-2392
Bogojeska, Jasmina
Alexa, Adrian
Altmann, André
Lengauer, Thomas
[Rahnenführer, Jörg]
2008Journal Article
Sarcoidosis is associated with a truncating splice site mutation in BTNL2
In: Nature Genetics [37], 357-364
[Valentonyte, Ruta]
[Hampe, Jochen]
[Huse, Klaus]
[Rosenstiel, Philip]
Albrecht, Mario
[Stenzel, Annette]
[Nagy, Marion]
[Gaede, Karoline I.]
[Franke, Andre]
[Haesler, Robert]
[Koch, Andreas]
Lengauer, Thomas
[Seegert, Dirk]
[Reiling, Norbert]
[Ehlers, Stefan]
[Schwinger, Eberhard]
[Platzer, Mathias]
[Krawczak, Michael]
[Müller-Quernheim, Joachim]
[Schürmann, Manfred]
[Schreiber, Stefan]
2005Journal Article
Scoring pathway activity from gene
expression data
Universität des Saarlandes
Bayjanov, Jumamurat2004Thesis - Masters thesis
Screening for HIV tropism using population-based V3 genotypic analysis: a retrospective outcome analysis using stored plasma screening samples from MOTIVATE-1
In: Abstracts presented at the XVIII International HIV Drug Resistance Workshop : Basic Principles & Clinical Implications, A17-A17
[Harrigan, P Richard]
[McGovern, Rachel]
[Dong, Winnie]
Thielen, Alexander
[Jensen, Mark]
[Mo, Theresa]
[Chapman, Douglas]
[Lewis, Marilyn]
[James, Ian]
[Valdez, Hernan]
2009Poster
Selecting anti-HIV therapies based on a variety of genomic and clinical factors
In: Proceedings of the 16th Annual International Conference on Intelligent Systems for Molecular Biology (ISMB 2008), i399-406
[Rosen-Zvi, Michal]
Altmann, Andre
[Prosperi, Mattia]
[Aharoni, Ehud]
[Neuvirth, Hani]
[Sönnerborg, Anders]
[Schülter, Eugen]
[Struck, Daniel]
[Peres, Yardena]
[Incardona, Francesca]
[Kaiser, Rolf]
[Zazzi, Maurizio]
Lengauer, Thomas
2008Proceedings Article
Attachment IconSelective pressures of HLA genotypes and antiviral therapy on human immunodeficiency virus type 1 sequence mutation at a population level
In: Clinical and Vaccine Immunology [14], 1266-1273
[Ahlenstiel, G.]
Roomp, Kirsten
Däumer, Martin
[Nattermann, T.]
[Vogel, M.]
[Rockstroh, J.K.]
Beerenwinkel, Niko
Kaiser, R.
[Nischalke, H.-D.]
[Sauerbruch, T.]
Lengauer, Thomas
[Spengler, U.]
2007Journal Article
Attachment IconSemi-Supervised Learning for Predicting Anti-HIV Drug Resistance
Universität des Saarlandes
Perner, Juliane2008Thesis - Bachelor thesis
Sensitive detection of viral transcripts in human tumor transcriptomes
In: PLOS Computational Biology [9], xx
Schelhorn, Sven-Eric
[Fischer, M.]
[Tolosi, Laura]
[Altmüller, J.]
[Nürnberg, P.]
[Pfister, H.]
Lengauer, Thomas
Berthold, F.
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Sequence variants in IL10, ARPC2, and multiple other loci contribute to ulcerative colitis
In: Nature Genetics [40], 1319-1323
[Franke, Andre]
[Balschun, Tobias]
[Karlsen, Tom H.]
[Sventoraityte, Jurgita]
[Nikolaus, Susanna]
Mayr, Gabriele
Domingues, Francisco S.
Albrecht, Mario
[Nothnagel, Michael]
[Ellinghaus, David]
[Sina, Christian]
[Onnie, Clive M.]
[Weersma, Rinse K.]
[Stokkers, Pieter C. F.]
[Wijmenga, Cisca]
[Gazouli, Maria]
[Strachan, David]
[McArdle, Wendy L.]
[Vermeire, Séverine]
[Rutgeers, Paul]
[Rosenstiel, Philip]
[Krawczak, Michael]
[Vatn, Morten H.]
[IBSEN study group, the]
[Mathew, Christopher G.]
[Schreiber, Stefan]
2008Journal Article
Short Communication: Selection of Thymidine Analogue Resitance Mutational Patterns in Children from a Common HIV Type 1 Subtype G Source
In: AIDS Research and Human Retroviruses [26], 275-278
[Däumer, Martin]
[Awerkiew, Sabine]
[Sierra Aragon, Saleto]
[Kartashev, Vladimir]
[Poplavskaja, Tatjana]
[Klein, Rolf]
[Sichtig, Nadine]
[Thielen, Bernhard]
Lengauer, Thomas
Roomp, Kirsten
[Pfister, Herbert]
[Kaiser, Rolf]
2010Journal Article
Simple consensus procedures are effective and sufficient in secondary structure prediction
In: Protein Engineering [16], 459-462
Albrecht, Mario
[Tosatto, Silvio C.E.]
Lengauer, Thomas
[Valle, Giorgio]
2003Journal Article
Software tool for automated processing of 13C labeling data from mass spectrometry data
In: BioTechniques [35], 1214-1215
Talwar, Priti
[Wittmann, Christoph]
Lengauer, Thomas
[Heinzle, Elmar]
2003Journal Article
Somatic hypermutation and mRNA expression levels of the BCL-6 gene in patients with hepatitis C virus-associated lymphoproliferative diseases
In: Journal of Viral Hepatitis [14], 484-491
[Hofmann, Wolf Peter]
[Fernandez, B.]
[Herrmann, E.]
Welsch, Christoph
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[Kronenberg, B.]
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[Zeuzem, Stefan]
[Sarrazin, Christoph]
2007Journal Article
Specificity of linear motifs that bind to a common mitogen-activated protein kinase docking groove
In: Science Signaling [5], ra74,1-ra74,14
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[Zeke, András]
[Gógl, Gergo]
[Töro, Imre]
[Fördos, Ferenc]
Blankenburg, Hagen
[Bárkai, Tünde]
[Varga, János]
[Alexa, Anita]
Emig, Dorothea
Albrecht, Mario
[Reményi, Attila]
2012Journal Article
Stability analysis of mixtures of mutagenetic trees
In: BMC Bioinformatics [9], 165-181
Bogojeska, Jasmina
Lengauer, Thomas
[Rahnenführer, Jörg]
2008Journal Article
Stability analysis of oncogenetic trees mixture models
Universität des Saarlandes
Bogojeska, Jasmina2007Thesis - Masters thesis
Stable coreceptor usage of HIV-1 in patients with ongoing treatment failure on HAART
In: Proceedings of the 3rd European HIV Drug Resistance Workshop, -
[Kaiser, Rolf]
[Boussaad, Ibo]
[Lehmann, C.]
[Däumer, Martin]
Sing, Tobias
[Schmeisser, N.]
[Wyen, C.]
Fätkenheuer, Gerd
2005Proceedings Article
Stable coreceptor usage of HIV in patients with ongoing treatment failure on HAART
In: Journal of Clinical Virology [37], 300-304
[Lehmann, Clara]
[Däumer, Martin]
[Bousaad, Ibrahim]
Sing, Tobias
[Beerenwinkel, Niko]
Lengauer, Thomas
[Schmeisser, Norbert]
[Wyen, Christoph]
[Fätkenheuer, Gerd]
[Kaiser, Rolf]
2006Journal Article
Statistical Inference for Clustering Microarrays
In: Proceedings of the MSRI Workshop: Nonlinear Estimation and Classification, 323-332
Rahnenführer, Jörg[Denison, David D.]
[Hansen, Mark H.]
[Holmes, Christopher C.]
[Mallick, Bani]
[Yu, Bin]
2003Proceedings Article
Attachment IconStatistical Learning Methods for Bias-aware HIV Therapy Screening
Universität des Saarlandes
Bogojeska, Jasmina2011Thesis - PhD thesis
Statistical methods for the biological interpretation of genome-wide measurements
Universität des Saarlandes
Rahnenführer, Jörg2006Thesis - Habilitation thesis
Attachment IconStochastic Gradient Descent Training of Ensembles of DT-CNN Classifiers for Digit Recognition
In: Proceedings of the 16th European Conference on Circuit Theory and Design ECCTD'03, 337-341
Merkwirth, Christian
[Ogorzalek, Maciej]
[Wichard, Jörg Daniel]
[Ogorzalek, Maciej]
[Galias, Zbigniew]
[Garda, Bartlomiej]
[Kadeja, Bartlomiej]
2003Proceedings Article
Strategiekonzept "Molekulare Bioinformatik"
In: Informatikforschung in Deutschland, 9
Lengauer, ThomasReuse, Bernd
Vollmar, Roland
2007Part of a Book
Structural and functional analysis of a novel mutation of CYP21B in a heterozygote carrier of 21-hydroxylase deficiency
In: Human Genetics [117], 558-564
[Bojunga, Jörg]
[Welsch, Christoph]
Antes, Iris
Albrecht, Mario
Lengauer, Thomas
[Zeuzem, Stefan]
2005Journal Article
Structural and functional analysis of ataxin-2 and ataxin-3
In: European Journal of Biochemistry [271], 3155-3170
Albrecht, Mario
[Golatta, Michael]
[Wüllner, Ullrich]
Lengauer, Thomas
2004Journal Article
Structural and functional comparison of the non-structural protein 4B of flaviviridae
In: Journal of Molecular Graphics and Modeling [26], 546-557
Welsch, Christoph
Albrecht, Mario
Maydt, Jochen
[Herrmann, E.]
[Welker, M.W.]
[Sarrazin, C.]
[Scheidig, A.]
Lengauer, Thomas
Zeuzem, S.
2007Journal Article
Attachment IconStructural conservation versus functional divergence of maternally expressed microRNAs in the Dlk1/Gtl2 imprinting region
In: BMC Genomics [9], 346
Kircher, Martin
Bock, Christoph
Paulsen, Martina
2008Journal Article
Structural Descriptors for the Analysis of Protein Structure, Function, and Evolution
Universität des Saarlandes
Sander, Oliver2008Thesis - PhD thesis
Attachment IconStructural Descriptors of gp120 V3 Loop for the Prediction of HIV-1 Coreceptor Usage
In: PLoS Computational Biology [3], 555-564
Sander, Oliver
Sing, Tobias
Sommer, Ingolf
[Low, Andrew J.]
[Cheung, Peter K.]
[Harrigan, P. Richard]
Lengauer, Thomas
Domingues, Francisco S.
2007Journal Article
Structural descriptors of protein-protein binding sites
In: Proceedings of 6th Asia-Pacific Bioinformatics Conference, 79-88
Sander, Oliver
Domingues, Francisco S.
Zhu, Hongbo
Lengauer, Thomas
Sommer, Ingolf
[Brazma, Alvis]
[Miyano, Satoru]
[Akutsu, Tatsuya]
2008Proceedings Article
Structural localization of disease-associated sequence variations in the NACHT and LRR domains of PYPAF1 and NOD2
In: FEBS Letters [554], 520-528
Albrecht, Mario
Domingues, Francisco S.
[Schreiber, Stefan]
Lengauer, Thomas
2003Journal Article
Structural modeling of ataxin-3 reveals distant homology to adaptins
In: Proteins: Structure, Function, and Genetics [50], 355-370
Albrecht, Mario
[Hoffmann, Daniel]
[Evert, Bernd O.]
[Schmitt, Ina]
[Wüllner, Ullrich]
Lengauer, Thomas
2003Journal Article
Structure-based prediction of HIV-1 drug resistance
Universität des Saarlandes
Fischer, Sandra2008Thesis - Masters thesis
Structure-function analysis of the NB-ARC domain of plant disease resistance proteins
In: Journal of Experimental Botany [59], 1383-1397
[Van Ooijen, Gerben]
Mayr, Gabriele
[Kasiem, Mobien M. A.]
Albrecht, Mario
[Cornelissen, Ben J. C.]
[Takken, Frank L. W.]
2008Journal Article
Structure collisions between interacting proteins
In: PLoS ONE [6], e19581,1-e19581,7
Emig, Dorothea
Sander, Oliver
Mayr, Gabriele
Albrecht, Mario
2011Electronic Journal Article
Structure to function
In: Modern Genome Annotation, 239-262
[Watson, James D.]
[Thornton, Janet M.]
[Tress, Michael L.]
[Lopez, Gonzalo]
[Valencia, Alfonso]
[Redfern, Oliver]
[Orengo, Christine A.]
Sommer, Ingolf
Domingues, Francisco S.
[Frishman, Dmitrij]
[Valencia, Alfonso]
2008Part of a Book
Survey on the PABC recognition motif PAM2
In: Biochemical and Biophysical Research Communications [316], 129-138
Albrecht, Mario
Lengauer, Thomas
2004Journal Article
Sustaining lamivudine/emtricitabine, abacavir, zidovudine or atazanavir from a previous treatment shows a clinical benefit
In: Antiviral Therapy, A86
[Rosen-Zvi, Michal]
[Schülter, Eugen]
Altmann, Andre
[Sierra-Aragon, Saleta]
[Zazzi, Maurizio]
[Sönnerborg, Anders]
[Oette, Mark]
Lengauer, Thomas
[Kaiser, Rolf]
2008Poster
Synthesis and evaluation of heteroaryl substituted dihydronaphthalenes and indenes: potent and selective inhibitors of aldosterone synthase (CYP11B2) for the treatment of congestive heart failure and myocardial fibrosis
In: Journal of Medicinal Chemistry [49], 2222-2231
[Voets, Marieke]
Antes, Iris
[Scherer, Christiane]
[Müller-Vieira, Ursula]
[Biemel, Klaus]
[Marchais-Oberwinkler, Sandrine]
[Hartmann, Rolf W.]
2006Journal Article
Synthesis and Evaluation of Imidazolylmethylenetetrahydronaphthalenes and Imidazolylmethyleneindanes: Potent Inhibitors of Aldosterone Synthase
In: Journal of Medicinal Chemistry [48], 1796-1805
[Ulmschneider, Sarah]
[Mueller-Vieira, Ursula]
[Mitrenga, Markus]
[Hartmann, Rolf W.]
[Oberwinkler-Marchais, S]
[Klein, Christian D.]
[Bureik, M.]
[Bernhardt, R.]
Antes, Iris
Lengauer, Thomas
2005Journal Article
Synthesis and Evaluation of Pyridylmethylene-tetrahydronaphthalenes and -indanes: Potent and Selective Inhibitors of Aldosterone Synthase (CYP11B2)
In: Journal of Medicinal Chemistry [48], 4489-4490
[Ulmschneider, Sarah]
[Mueller-Vieira, Ursula]
[Klein, Christian D.]
Antes, Iris
Lengauer, Thomas
[Hartmann, Rolf W.]
2005Journal Article
Systematic association mapping identifies NELL1 as a novel IBD disease gene
In: PLoS ONE [2], e691.1-13
[Franke, Andre]
[Hampe, Jochen]
[Rosenstiel, Philip]
[Becker, Christoph]
[Wagner, Florian]
[Häsler, Robert]
[Little, Randall D.]
[Huse, Klaus]
[Ruether, Andreas]
[Balschun, Tobias]
[Wittig, Michael]
[ElSharawy, Abdou]
Mayr, Gabriele
Albrecht, Mario
[Prescott, Natalie J.]
[Onnie, Clive M.]
[Fournier, Hélène]
[Keith, Tim]
[Radelof, Uwe]
[Platzer, Matthias]
[Mathew, Christopher G.]
[Stoll, Monika]
[Krawczak, Michael]
[Nürnberg, Peter]
[Schreiber, Stefan]
2007Journal Article
Tenofovir resistance and resensitization
In: Antimicrobial Agents and Chemotherapy [47], 3478-3484
[Wolf, Katharina]
[Walter, Hauke]
Beerenwinkel, Niko
[Keulen, Wilco]
[Kaiser, Rolf]
[Hoffmann, Daniel]
Lengauer, Thomas
[Selbig, Joachim]
[Vandamme, Anne-Mieke]
[Korn, Klaus]
[Schmidt, Barbara]
2003Journal Article
The EuResist approach for predicting response to anti HIV-1 therapy
In: Reviews in Antiviral Therapy, 107
Altmann, Andre
[Rosen-Zvi, Michal]
[Prosperi, Mattia]
[Aharoni, Ehud]
[Neuvirth, Hani]
[Schülter, Eugen]
Büch, Joachim
[Peres, Yardena]
[Incardona, Incardona]
[Sönnerborg, Anders]
[Kaiser, Rolf]
[Zazzi, Maurizio]
Lengauer, Thomas
2008Poster
The formation of a β-Peptide/DPC-micelle complex studied by MD simulationsAntes, Iris
[Klein, Michael L.]
2001Miscellaneous
The Helmholtz Network for Bioinformatics: an integrative web portal for bioinformatics resources
In: Bioinformatics [20], 268-270
[Crass, T.]
Antes, Iris
[Basekow, R.]
[Bork, P.]
Buning, Christian
[Christensen, M.]
[Claußen, H.]
[Ebeling, C.]
[Ernst,P.]
[Gailus-Durner, V.]
[Glatting, K.-H.]
[Gohla, R.]
[Gößling, F.]
[Grote, K.]
[Heidtke, K.]
[Herrmann, A.]
[O Keefe, S.]
[Kießlich, O.]
[Kolibal, S.]
[Korbel, J.O.]
Lengauer, Thomas
[Liebich, I.]
[van der Linden, M.]
[Luz, H.]
[Meissner, K.]
[von Mering, C.]
[Mevissen, T.]
[Mewes, H.-W.]
[Michael, H.]
[Mokrejs, M.]
[Müller, T.]
[Pospisil, H.]
[Rarey, Matthias]
[Reich, J.G.]
[Schneider, R.]
[Schomburg, D.]
[Schulze-Kremer, S.]
[Schwarzer, K.]
Sommer, Ingolf
[Springstubbe, S.]
[Suhai, S.]
[Thoppae, G.]
[Vingron, M.]
[Warfsmann, J.]
[Werner, T.]
[Wetzler, D.]
[Wingender, E.]
[Zimmer, Ralf]
2004Journal Article
The HIN domain of IFI-200 proteins consists of two OB folds
In: Biochemical and Biophysical Research Communications [327], 679-687
Albrecht, Mario
[Choubey, Divaker]
Lengauer, Thomas
2005Journal Article
Attachment IconThe human genomic melting map
In: PLoS Computational Biology [3], e93
[Liu, Fang]
[Tostesen, Eivind]
[Sundet, Jostein K.]
[Jenssen, Tor-Kristian]
Bock, Christoph
[Jerstad, Geir Ivar]
[Thilly, William G.]
[Hovig, Eivind]
2007Journal Article
The Impact of Alternative Splicing on Protein Interaction Networks
Eberhard Karls Universität Tübingen
Emig, Dorothea2007Thesis - other
Attachment IconThe implications of alternative splicing in the ENCODE protein complement
In: Proceedings of the National Academy of Sciences [104], 5495-5500
[Tress, Michael L.]
[Martelli, Pier L.]
[Frankish, Adam]
[Reeves, Gabrielle A.]
[Wesselink, Jan J.]
[Yeats, Corin]
[Ólason, Páll Í.]
Albrecht, Mario
[Hegyi, Hedi]
[Giorgetti, Alejandro]
[Raimondo, Domenico]
[Lagarde, Julien]
[Laskowski, Roman A.]
[López, Gonzalo]
[Sadowski, Michael I.]
[Watson, James D.]
[Fariselli, Piero]
[Rossi, Ivan]
[Nagy, Alinda]
[Kai, Wang]
[Størling, Zenia]
[Orsini, Massimiliano]
Assenov, Yassen
Blankenburg, Hagen
Huthmacher, Carola
Ramírez, Fidel
Schlicker, Andreas
[Denoued, France]
[Jones, Phil]
[Kerrien, Samuel]
[Orchard, Sandra]
[Antonarakis, Stylianos E.]
[Reymond, Alexandre]
[Birney, Ewan]
[Brunak, Søren]
[Casadio, Rita]
[Guigo, Roderic]
[Harrow, Jennifer]
[Hermjakob, Henning]
[Jones, David T.]
Lengauer, Thomas
[Orengo, Christine A.]
[Patthy, László]
[Thornton, Janet M.]
[Tramontano, Anna]
[Valencia, Alfonso]
2007Journal Article
The role of genomics in tracking the evolution of influenza A virus
In: PLoS Pathog [5], e1000566
McHardy, Alice C.
Adams, Ben
2009Electronic Journal Article
The unbinding of ATP from F1-ATPase
In: Biophysical Journal [85], 695-706
Antes, Iris
[Wang, Hongyun]
[Chandler, David]
[Oster, George]
2003Journal Article
Theoretical and Experimental Evaluation of a CYP106A2 Low Homology Model and Production of Mutants with Changed Activity and Selectivity of Hydroxylation
In: ChemBioChem [9], 1439-1449
[Lisurek, Michael]
[Simgen, Birgit]
Antes, Iris
[Bernhardt, Rita]
2008Journal Article
Tissue-specific proteins and functional implications
In: Journal of Proteome Research [10], 1893-1903
Emig, Dorothea
Albrecht, Mario
2011Journal Article
Topological analysis and interactive visualization of biological networks and protein structures
In: Nature Protocols [7], 670-685
Doncheva, Nadezhda T
Assenov, Yassen
[Domingues, Francisco S.]
Albrecht, Mario
2012Journal Article
Topological Analysis of Biological
Networks
Universität des Saarlandes
Assenov, Yassen2006Thesis - Masters thesis
Towards cellular function through metabolite screening
In: Proceedings of the 3rd Annual Conference on Metabolic Profiling: Pathways in Discovery, 7
Talwar, Priti
Lengauer, Thomas
[Wittmann, Christoph]
[Mangadu, Vidya]
[Heinzle, Elmar]
2003Proceedings Article
Attachment IconTowards Comparative Epigenomics: A Pilot Study on DNA Methylation of CpG Islands on Human Chromosome 21
Universität des Saarlandes
Feuerbach, Lars2007Thesis - Masters thesis
Towards Comparative Epigenomics: A Software Toolkit For Cross-Species Epigenome Data Analysis
In: Abstracts of the 2nd MC-GARD Meeting, 230
Feuerbach, Lars
Christopher, Bock
Halachev, Konstantin
Büch, Joachim
Lengauer, Thomas
[Meijer, Gerrit]
[Ried, Thomas]
[Giaretti, Walter]
[Hamilton, Peter]
2008Electronic Proceedings Article
Towards computational analysis of metabolic profiling data for protein function prediction.
In: Proceedings of the Yeast Systems Biology, 6th International Conference on Systems Biology (ICSB 2005), 1
Talwar, Priti
Lengauer, Thomas
Rahnenführer, Jörg
[Heinzle, Elmar]
[Velagapudi, VR]
[Wittmann, Christoph]
2005Poster
Towards optimal alignment of protein structure distance matrices
In: Bioinformatics [26], 2273-2280
[Wohlers, Inken]
Domingues, Francisco S.
[Klau, Gunnar W.]
2010Journal Article
Towards the identification of cancer subtypes by integrative clustering of molecular data
Universität des Saarlandes
Speicher, Nora2012Thesis - Masters thesis
Transcomplementation, but not physical association of the CC-NB-ARC and LRR domains of tomato R protein Mi-1.2 is altered by mutations in the ARC2 subdomain
In: Molecular Plant [1], 401-410
[Van Ooijen, Gerben]
Mayr, Gabriele
Albrecht, Mario
[Cornelissen, Ben J. C.]
[Takken, Frank L. W.]
2008Journal Article
Tree models for the evolution of drug resistance
In: XII International HIV Drug resistance Workshop, S107-S107
Beerenwinkel, Niko
[Kaiser, Rolf]
Rahnenführer, Jörg
[Däumer, Martin]
[Hoffmann, Daniel]
[Selbig, Joachim]
Lengauer, Thomas
[Boucher, Charles]
[Mellors, John]
[Larder, Brendan]
[Richman, Douglas]
2003Proceedings Article
Truncation mutations in ABCA1 suppress normal upregulation of full-length ABCA1 by 9-cis-retinoic acid and 22-R-hydroxycholesterol
In: Journal of Lipid Research [43], 1939-1949
[Wellington, Cheryl L.]
[Yang, Yu-Zhou]
[Zhou, Stephen]
[Clee, Susanne M.]
[Tan, Bing]
[Hirano, Kenichi]
[Zwarts, K.Y.]
[Kwok, Anita]
[Gelfer, Allison]
[Marcil, Michel]
[Newman, Scott]
Roomp, Kirsten
[Singaraja, Roshni]
[Collins, Jennifer A.]
[Zhang, Lin-Hua]
[Groen, Albert K.]
[Hovingh, Kees]
[Brownlie, Alison]
[Tafuri, Sherrie]
[Genest, Jacques Jr]
[Kastelein, J.J.P.]
[Hayden, Michael R.]
2002Journal Article
Tutorial Cytoscape
In: Bioinformática: Aplicaciones a la genómica y proteómica, 73-98
Ramirez, Fidel[Gomez Merino, Fernando Carlos]
[Silva Rojas, Hilda Victoria]
[Pérez Rodríguez, Paulino]
2010Part of a Book
Unsupervised dissection of cancer types based on genomic, epigenomic and transciptomic features
Universität des Saarlandes
Junge, Alexander2011Thesis - Bachelor thesis
Unsupervised technique for robust target separation and analysis of DNA microarray spots through adaptive pixel clustering
In: Bioinformatics [18], 747-756
Rahnenführer, Jörg
[Bozinov, Daniel]
2002Journal Article
Update on the domain architectures of NLRs and R proteins
In: Biochemical and Biophysical Research Communications [339], 459-462
Albrecht, Mario
[Takken, Frank L. W.]
2006Journal Article
Using copy number variation fpr predicting susceptibility to glioblastoma
Universität des Saarlandes
Dörr, Barbara2010Thesis - Bachelor thesis
Using multidimensional Scaling for visualizing similarities of proteins
Universität des Saarlandes
Weimann, Aaron2009Thesis - Bachelor thesis
Using Shape Retrieval Techniques for Identifying Similar Protein Binding Sites
Universität des Saarlandes
Müller, Oliver2007Thesis - Masters thesis
V3 loop sequence space analysis suggests different evolutionary patterns of CCR5- and CXCR4-tropic HIV.
In: PLoS One [4], e7387:1-e.7387:14
Bozek, Kasia
Thielen, Alexander
Sierra, Saleta
[Kaiser, Rolf]
Lengauer, Thomas
2009Electronic Journal Article
Validation of geno2pheno and THEO on a large independent clinical dataset
In: Proceedings of the 5th European HIV Drug Resistance Workshop, -
Altmann, Andre
[Däumer, Martin]
Sing, Tobias
[Beerenwinkel, Niko]
[Walter, Hauke]
[Kaiser, Rolf]
Lengauer, Thomas
2007Poster
Attachment IconVariants in a novel epidermal collagen gene (COL29A1) are associated with atopic dermatitis
In: PLoS Biology [5], e242.1952-1961
[Söderhäll, Cilla]
[Marenholz, Ingo]
[Kerscher, Tamara]
[Rüschendorf, Franz]
[Esparza-Gordillo, Jorge]
[Worm, Margitta]
[Gruber, Christoph]
Mayr, Gabriele
Albrecht, Mario
[Rohde, Klaus]
[Schulz, Herbert]
[Wahn, Ulrich]
[Hubner, Norbert]
[Lee, Young-Ae]
2007Journal Article
Viral Bioinformatics
In: Modern Genome Annotation - The BioSapiens Network, 429-452
Adams, Ben
McHardy, Alice
[Lundegaard, C.]
Lengauer, Thomas
Frishman, Dimitrij
Valencia, Alfonso
2009Part of a Book
Virtual screening for guest molecules of a biosensor
In: Biosensors 2006: The ninth world congress on biosensors, O66
Steffen, Andreas
Kämper, Andreas
Lengauer, Thomas
[Turner, Anthony P. F.]2006Proceedings Article
Virtual Screening for novel Urease Inhibitors
In: Proceedings of the International Workshop on New Approaches in Drug Design & Discovery, 39
Kämper, Andreas
Lengauer, Thomas
2003Poster
Visualizing domain interaction networks and the impact of alternative splicing events
In: Proceedings of the 5th International Conference on BioMedical Visualization (MediVis): Information Visualization in Medical and Biomedical Informatics, 36-43
Emig, Dorothea
[Klein, Karsten]
[Kunert, Anne]
[Mutzel, Petra]
Albrecht, Mario
2008Proceedings Article
Web-based analysis of (epi-) genome data using EpiGRAPH and Galaxy.
In: Genetic Variation : Methods and Protocols, 275-296
In: Methods of Molecular Biology [628], 275-296
Bock, Christoph
[Von Kuster, Greg]
Halachev, Konstantin
[Taylor, James]
[Nekrutenko, Anton]
Lengauer, Thomas
[Barnes, Michael R.]
[Breen, Gerome]
2010Part of a Book
Web Implementation of the HBV Dual Infection Model
Universität des Saarlandes
Döring, Matthias2011Thesis - Bachelor thesis
Why Do Hubs in the Yeast Protein Interaction Network Tend To Be Essential: Reexamining the Connection between the Network Topology and Essentiality
In: PLoS Computational Biology [4], e1000140
Zotenko, Elena
Mestre, Julian
[O'Leary, Dianne]
[Przytycka, Teresa]
2008Journal Article
WILMA-automated annotation of protein sequences
In: Bioinformatics [20], 127-128
[Prlic, Andreas]
Domingues, Francisco S.
[Lackner, Peter]
[Sippl, Manfred J.]
2004Journal Article
Yamada Analyzer - A tool for fast calculation of genomic attributes
Universität des Saarlandes
Jung, Holger2006Thesis - Bachelor thesis

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