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MPI-INF D3 Publications, generated: 5:23, 25 August 2019

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Your search returned the following 37 documents:

  1. Alexander Thielen and Thomas Lengauer
    Geno2pheno[454]: A Web Server for the Prediction of HIV-1 Coreceptor Usage from Next-Generation Sequencing Data
    Intervirology 55: 113-117, 2012
  2. Martin Obermeier, Alejandro Pironti, Thomas Berg, Patrick Braun, Martin Däumer, Josef Eberle, Robert Ehret, Rolf Kaiser, Niels Kleinkauf, Klaus Korn, Claudia Kücherer, Harm Müller, Christian Noah, Martin Stürmer, Alexander Thielen, Eva Wolf, and Hauke Walter
    HIV-GRADE: A Publicly Available, Rules-Based Drug Resistance Interpretation Algorithm Integrating Bioinformatic Knowledge
    Intervirology 55: 102-107, 2012
  3. Saleta Sierra, Jan Nikolaj Dzbowski, Alejandro Pironti, L Gueney, Alexander Thielen, Stefan Reuter, Stefan Esser, Gerd Fätkenheuer, Thomas Lengauer, Dominik Hider, Daniel Hoffmann, Holger Pfister, Björn Jensen, and Rolf Kaiser
    Optimisation of baseline genotypic testing for safe and efficient maraviroc administration
    In: Journal of the International AIDS Society, Glasgow, UK, 2012, 101-102
  4. Eva Heger, Alexander Thielen, Ramona Gilles, Martin Obermeier, Thomas Lengauer, Rolf Kaiser, and Susanna Trapp
    APOBEC3G/F a one possible driving source for co-receptor switch of the human immunodeficiency virus-1
    Medical Microbiology and Immunology 201 (1): 7-16, 2012
  5. Francisco Codoner, Christian Pou, Alexander Thielen, Federico García, Rafael Delgado, David Dalmau, Miguel Álvarez-Tejado, Lidia Ruiz, Bonaventura Clotet, and Roger Paredes
    Added value of deep sequencing relative to population sequencing in heavily pre-treated HIV-1-infected subjects
    PLoS One 6 (5): e19461,1-e19461,5, 2011
  6. Eva Heger, Alexander Thielen, Ramona Gilles, Martin Obermeier, Thomas Lengauer, Rolf Kaiser, and Susanna Trapp
    APOBEC3G/F as one possible driving force for co-receptor switch of the human immunodeficiency virus-1
    Medical Microbiology and Immunology 201 (1): 7-16, 2011
  7. Luke C. Swenson, Theresa Mo, Winnie W. Y. Dong, Xiaoyin Zhong, Conan K. Woods, Mark A. Jensen, Alexander Thielen, Douglass Chapman, Marilyn Lewis, Ian James, Jayvant Heera, Hernan Valdez, and P. Richard Harrigan
    Deep Sequencing to Infer HIV-1 Co-Receptor Usage: Application to Three Clinical Trials of Maraviroc in Treatment-Experienced Patients
    The Journal of Infectious Diseases 203 (3): 237-245, 2011
  8. Luke C Swenson, Theresa Mo, Winnie WY Dong, Xiaoyin Zhong, Conan K Woods, Alexander Thielen, Mark A Jensen, David JHF Knapp, Douglass Chapman, Marilyn Lewis, Ian James, Jayvant Heera, Hernan Valdez, and P Richard Harrigan
    Deep V3 sequencing for HIV type 1 tropism in treatment-naive patients: a reanalysis of the MERIT trial of maraviroc.
    Clinical Infectious Diseases 53 (7): 732-742, 2011
  9. Alexander Thielen
    Genotypic Analysis of HIV-1 Coreceptor Usage
    Doctoral dissertation, Universität des Saarlandes, 2011
  10. Martin Däumer, Rolf Kaiser, Rolf Klein, Thomas Lengauer, Bernhard Thiele, and Alexander Thielen
    Genotypic tropism testing by massively parallel sequencing: qualitative and quantitative analysis
    BMC Medical Informatics and Decision Making 11 (1): 30,1-30,8, 2011
  11. Eduardo Seclen, Vincente Soriano, Maria M González, Sagrario Gómez, Alexander Thielen, and Eva Poveda
    High Concordance between the Position-Specific Scoring Matrix and Geno2pheno Algorithms for Genotypic Interpretation of HIV-1 Tropism: V3 Length as the Major Cause of Disagreement
    Journal of Clinical Microbiology 49: 3380-3382, 2011
  12. Stefanie Knoepfel, Francesca Di Giallonardoc, Martin Däumer, Alexander Thielen, and Karin J Metzner
    In-depth analysis of G-to-A hypermutation rate in HIV-1 env DNA induced by endogenous APOBEC3 proteins using massively parallel sequencing
    Journal of Virological Methods 71 (2): 329-338, 2011
  13. Alexander Thielen, Thomas Lengauer, Luke C Swenson, Winnie W.Y. Dong, Rachel A McGovern, Marilyn Lewis, Ian James, Jayvant Heera, Hernan Valdez, and P Richard Harrigan
    Mutations in gp41 are correlated with coreceptor tropism but do not improve prediction methods substantially
    Antiviral Therapy 16 (3): 319-328, 2011
  14. Saleta Sierra, Rolf Kaiser, Nadine Lübke, Alexander Thielen, Eugen Schuelter, Eva Heger, Martin Däumer, Stefan Reuter, Stefan Esser, Gerd Fätkenheuer, Herbert Pfister, Mark Oette, and Thomas Lengauer
    Prediction of HIV-1 coreceptor usage (tropism) by sequence analysis using a genotypic approach
    Journal of Visualized Experiments 58: e3264,1-e3264,9, 2011
  15. Thomas Lengauer, André Altmann, Alexander Thielen, and Rolf Kaiser
    Chasing the AIDS Virus
    Communications of the ACM 53 (3): 66-74, 2010
  16. Christel Kamp, Timo Wolf, Ignacio G Bravo, Benjamin Kraus, Birgit Krause, Britta Neumann, Gudrun Winskowsky, Alexander Thielen, Albrecht Werner, and Barbara S Schnierle
    Decreased HIV diversity after allogeneic stem cell transplantation of an HIV-1 infected patient: a case report.
    Virology Journal 7 (1): 55,1-55,9, 2010
  17. Francisco M Codoñer, Christian Pou, Alexander Thielen, Federico García, Rafael Delgado, David Dalmau, José Ramon Santos, Maria José Buzón, Javier Alvarez-Tejado, Miguel Martínez-Picado, Bonaventura Clotet, Lidia Ruiz, and Roger Paredes
    Dynamic escape of pre-existing raltegravir-resistant HIV-1 from raltegravir selection pressure
    Antiviral Research 88 (3): 281-286, 2010
  18. Luke C. Swenson, Richard Boehme, Alexander Thielen, Rachel A. McGovern, and P. Richard Harrigan
    Genotypic determination of HIV-1 tropism in the clinical setting
    HIV Therapy 4 (3): 293-303, 2010
  19. Luke C. Swenson, Andrew Moores, Andrew J. Low, Alexander Thielen, Winnie Dong, Conan Woods, Mark A. Jensen, Brian Wynhoven, Dennison Chan, Christopher Glascock, and P. Richard Harrigan
    Improved detection of CXCR4-using HIV by V3 genotyping: application of population-based and "deep" sequencing to plasma RNA and proviral DNA
    Journal of Acquired Immune Deficiency Syndromes 54 (5): 506-510, 2010
  20. Alexander Thielen, Nadine Sichtig, Rolf Kaiser, Jeffrey Lam, P. Richard Harrigan, and Thomas Lengauer
    Improved prediction of HIV-1 coreceptor usage with sequence information from the second hypervariable loop of gp120
    Journal of Infectious Diseases 202 (9): 1435-1443, 2010
  21. Alexander Thielen, Thomas Lengauer, P Richard Harrigan, Luke Swenson, Winnie WY Dong, Rachel A McGovern, Marilyn Lewis, Ian James, Jayvant Heera, and Hernan Valdez
    Mutations within GP41 are correlated with coreceptor tropism but do not substantially improve coreceptor usage prediction
    In: Reviews in Antiviral Therapy & Infectious Diseases, Sorrento, Italy, 2010, 47-47
  22. Rachel A McGovern, Alexander Thielen, Theresa Mo, Winnie Dong, Conan K Woods, Douglass Chapman, Marilyn Lewis, Ian James, Jayvant Heera, Hernan Valdez, and P Richard Harrigan
    Population-based V3 genotypic tropism assay: a retrospective analysis using screening samples from the A4001029 and MOTIVATE studies
    AIDS 24 (16): 2517-2525, 2010
  23. Thomas Lengauer, André Altmann, and Alexander Thielen
    Bioinformatische Unterstützung der Auswahl von HIV Therapien
    Informatik Spektrum 32 (2): 320-331, 2009
  24. Alexander Thielen, André Altmann, Jasmina Bogojeska, Rolf Kaiser, and Thomas Lengauer
    Estimating evolutionary pathways to 7CXCR4 usage from cross-sectional data
    In: Abstracts presented at the XVIII International HIV Drug Resistance Workshop : Basic Principles & Clinical Implications, Fort Myers, USA, 2009, A16-A16, paper no. Abstract 14.
  25. Alexander Thielen, Nadine Sichtig, Patrick Braun, Martin Däumer, Hauke Walter, Christian Noah, Eva Wolf, Harm Müller, Martin Stürmer, Thomas Lengauer, Rolf Kaiser, and Martin Obermeier
    Performance of genotypic coreceptor measurement using geno2pheno[coreceptor] in B- and non-B HIV subtypes in a large cohort of therapy-experienced patients in Germany
    In: Reviews in Antiviral Therapy, Stockholm, Sweden, 2009, 99-99
  26. P Richard Harrigan, Rachel McGovern, Winnie Dong, Alexander Thielen, Mark Jensen, Theresa Mo, Douglas Chapman, Marilyn Lewis, Ian James, and Hernan Valdez
    Screening for HIV tropism using population-based V3 genotypic analysis: a retrospective outcome analysis using stored plasma screening samples from MOTIVATE-1
    In: Abstracts presented at the XVIII International HIV Drug Resistance Workshop : Basic Principles & Clinical Implications, Fort Myers, USA, 2009, A17-A17, paper no. Abstract 15.
  27. Kasia Bozek, Alexander Thielen, Saleta Sierra, Rolf Kaiser, and Thomas Lengauer
    V3 loop sequence space analysis suggests different evolutionary patterns of CCR5- and CXCR4-tropic HIV.
    PLoS One 4 (11): e7387:1-e.7387:14, 2009
  28. Martin Obermeier, Thomas Berg, Nadine Sichtig, Patrick Braun, Martin Däumer, Hauke Walter, Christian Noah, Eva Wolf, Harm Müller, Martin Stürmer, Alexander Thielen, and Rolf Kaiser
    Determination of HIV-1 co-receptor usage in German patients – comparison of genotypic methods with the TROFILE® phenotypic assay
    In: Abstracts of the Ninth International Congress on Drug Therapy in HIV Infection, Glasgow, UK, 2008, 123 p.
  29. Martin Obermeier, Nadine Sichtig, Patrick Braun, Martin Däumer, Hauke Walter, Christian Noah, Eva Wolf, Harm Müller, Martin Stürmer, Rolf Kaiser, and Alexander Thielen
    Determination of HIV-1 coreceptor usage in German patients - comparison of genotypic methods with the TROFILE phenotypic assay
    In: Antiviral Therapy, Sitges, Spain, 2008, A112 p.
  30. Saleta Sierra, Rolf Kaiser, Alexander Thielen, Oliver Sander, and Thomas Lengauer
    Genotypic Analysis of HIV Co-Receptor Usage
    In: Entry Inhibitoren - Neue Formen der HIV-Therapie, 2008, 31-39
  31. Andrew Moores, Alexander Thielen, Winnie Dong, Andrew J. Low, Conan Woods, Mark Jensen, Brian Wynhoven, Dennison Chan, Christopher Glascock, and P Richard Harrigan
    Improved detection of X4 virus by V3 genotyping: application to plasma RNA and proviral DNA
    In: Antiviral Therapy, Sitges, Spain, 2008, A99 p.
  32. Alexander Thielen, P Richard Harrigan, Andrew J. Low, A Moores, Andre Altmann, Kasia Bozek, Eva Heger, Nadine Sichtig, Rolf Kaiser, and Thomas Lengauer
    Improved genotypic prediction of HIV-1 coreceptor usage by incorporating V2 loop sequence variation
    In: Antiviral Therapy, Sitges, Spain, 2008, A100 p.
  33. Alexander Thielen, Rolf Kaiser, and Thomas Lengauer
    Improving HIV-1 coreceptor usage prediction from genotype with regions outside of V3
    In: Reviews in Antiviral Therapy, Washington, US, 2008, 81-82
  34. Martin Däumer, Rolf Kaiser, Rolf Klein, Thomas Lengauer, Bernhard Thiele, and Alexander Thielen
    Inferring viral tropism from genotype with massively parallel sequencing; qualitative and quantitative analysis
    In: Antiviral Therapy, Sitges, Spain, 2008, A101 p.
  35. Alexander Thielen
    Prediction of linear B-cell epitopes and MHC class II binding peptides
    Master's thesis, Eberhardt-Karls-Universität Tübingen, 2006
  36. Thomas Lengauer, Oliver Sander, Saleta Sierra, Alexander Thielen, and Rolf Kaiser
    Bioinformatics prediction of HIV coreceptor usage
    Nature Biotechnology 25 (12): 1407-1410, 2007
  37. Saleta Sierra, Rolf Kaiser, Alexander Thielen, and Thomas Lengauer
    Genotypic coreceptor analysis.
    European Journal of Medical Research 12 (9): 453-462, 2007