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MPI-INF D3 Publications

MPI-INF D3 Publications

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1
Hide details for GalataGalata
2012Applying Lasso regression to related cell types for gene network astimation
Universität des Saarlandes
Thesis - Bachelor thesis
1
Hide details for Garai, Zeke, Gógl, Töro, Fördos, Blankenburg, Bárkai, Varga, Alexa, Emig, Albrecht, ReményiGarai, Zeke, Gógl, Töro, Fördos, Blankenburg, Bárkai, Varga, Alexa, Emig, Albrecht, Reményi
2012Specificity of linear motifs that bind to a common mitogen-activated protein kinase docking groove
In: Science Signaling [5], ra74,1-ra74,14
Journal Article
1
Hide details for GatzmannGatzmann
2010GOdot Sequence - function prediction from protein sequence
Universität des Saarlandes
Thesis - Bachelor thesis
1
Hide details for GlaabGlaab
2006On the predictability of CpG methylation in human tissue at single basepair resolution
Universität des Saarlandes
Thesis - Bachelor thesis
1
Hide details for GuoGuo
2006Improving Fold Recognition Using Protein
and Domain Interactions
Universität des Saarlandes
Thesis - Masters thesis
1
Hide details for Gu, Bock, Mikkelsen, Jäger, Smith, Tomazou, Gnirke, Lander, MeissnerGu, Bock, Mikkelsen, Jäger, Smith, Tomazou, Gnirke, Lander, Meissner
2010Attachment IconGenome-scale DNA methylation mapping of clinical samples at single-nucleotide resolution
In: Nature Methods [7], 133-136
Journal Article
1
Hide details for Gu, Kofler, Antes, Freund, HelmsGu, Kofler, Antes, Freund, Helms
2005Alternative Binding Modes of Polyproline Peptides Binding to the GYF Domain
In: Biochemistry [44], 6404-6415
Journal Article
1
Hide details for Gu, Smith, Bock, Boyle, Gnirke, MeissnerGu, Smith, Bock, Boyle, Gnirke, Meissner
2011Preparation of reduced representation bisulfite sequencing libraries for genome-scale DNA methylation profiling
In: Nature Protocols [6], 468-481
Journal Article
1
Hide details for GwinnerGwinner
2009Assessing the Conservation of Protein Function on Evolutionary Defined Patches
Universität des Saarlandes
Thesis - Masters thesis
2
Hide details for Hahn, Costello, Lu, Lengauer, SchreiberHahn, Costello, Lu, Lengauer, Schreiber
2004Expression analysis for inflammatory bowel disease
In: Workshop Poster Competition, ?
Poster
2002Attachment IconExpression analysis for inflammatory bowel disease
In: Proceedings of the n?th Conference on, ?
Poster
1
Hide details for Hahn, Rahnenführer, Talwar, LengauerHahn, Rahnenführer, Talwar, Lengauer
2005Confirmation of human protein interaction data by human expression data
In: BMC Bioinformatics [6], 1-11
Journal Article
1
Hide details for HaidHaid
2007BSIFlex: Binding Site Identification including protein flexibility
Universität des Saarlandes
Thesis - Masters thesis
1
Hide details for HalachevHalachev
2006EpiGRAPHregression: A toolkit for (epi-)genomic correlation analysis and prediction of quantitative attributes
Universität des Saarlandes
Thesis - Masters thesis
2
Hide details for Halachev, Bast, Albrecht, Lengauer, BockHalachev, Bast, Albrecht, Lengauer, Bock
2012Attachment IconEpiExplorer: live exploration and global analysis of large epigenomic datasets
In: Genome Biology [13], R96,1-R96,14
Electronic Journal Article
2012EpiExplorer: live exploration and global analysis of large epigenomic datasets
In: Genome Biology [13], R96,1-R96,14
Journal Article
1
Hide details for Halachev, Bast, Lengauer, BockHalachev, Bast, Lengauer, Bock
2013Interactive exploration of large genome and epigenome datasets in real time
In: Genome Biology [13], xx
Journal Article
1
Hide details for Hampe, Franke, Rosenstiel, Till, Teuber, Huse, Albrecht, Mayr, De La Vega, Briggs, Günther, Prescott, Onnie, HHampe, Franke, Rosenstiel, Till, Teuber, Huse, Albrecht, Mayr, De La Vega, Briggs, Günther, Prescott, Onnie, Häsler, Sipos, Fölsch, Lengauer, Platzer, Mathew, Krawczak, Schreiber
2007A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1
In: Nature Genetics [39], 207-211
Journal Article
1
Hide details for Hanisch, Zien, Zimmer, LengauerHanisch, Zien, Zimmer, Lengauer
2002Co-clustering of biological networks and gene expression data
In: Proceedings of the Tenth Conference on Intelligent Systems for Molecular Biology (ISMB 2002), 145-154
Proceedings Article
1
Hide details for Hanisch, Zimmer, LengauerHanisch, Zimmer, Lengauer
2002ProML - the Protein Markup Language for specification of protein sequences, structures and families
In: In Silico Biology [2], 313 - 324
Journal Article
1
Hide details for Hannemann, Schön, Jansen, Putz, LengauerHannemann, Schön, Jansen, Putz, Lengauer
2004Modelling amorphous Si3B3N7: Structure and elastic properties
In: Physical Review [B 70], 144201-144201
Journal Article
1
Hide details for Harrigan, McGovern, Dong, Thielen, Jensen, Mo, Chapman, Lewis, James, ValdezHarrigan, McGovern, Dong, Thielen, Jensen, Mo, Chapman, Lewis, James, Valdez
2009Screening for HIV tropism using population-based V3 genotypic analysis: a retrospective outcome analysis using stored plasma screening samples from MOTIVATE-1
In: Abstracts presented at the XVIII International HIV Drug Resistance Workshop : Basic Principles & Clinical Implications, A17-A17
Poster
1
Hide details for Harris, Wang, Coarfa, Nagarajan, Hong, Downey, Johnson, Fouse, Delaney, Zhao, Olshen, Ballinger, Zhou, ForsberHarris, Wang, Coarfa, Nagarajan, Hong, Downey, Johnson, Fouse, Delaney, Zhao, Olshen, Ballinger, Zhou, Forsberg, Gu, Echipare, O'Geen, Lister, Pelizzola, Xi, Epstein, Bernstein, Hawkins, Ren, Chung, Gu, Bock, Gnirke, Zhang, Haussler, Ecker, Li, Farnham, Waterland, Meissner, Marra, Hirst, Milosavljevic, Costello
2010Comparison of sequencing-based methods to profile DNA methylation and identification of monoallelic epigenetic modifications
In: Nature Biotechnology [28], 1097-1105
Journal Article
1
Hide details for HartmannHartmann
2008Modeling of Flexible Side Chains for Protein-Ligand Docking
Universität des Saarlandes
Thesis - PhD thesis
2
Hide details for Hartmann, Antes, LengauerHartmann, Antes, Lengauer
2009Docking and scoring with alternative side-chain conformations
In: Proteins: Structure, Function, and Bioinformatics [74], 712-726
Journal Article
2007Attachment IconIRECS: A new algorithm for the selection of most probable ensembles of side-chain conformations in protein models.
In: Protein Science [16], 1294-1307
Journal Article
1
Hide details for HauschildHauschild
2011Modeling HIV Neutralization
Universität des Saarlandes
Thesis - Masters thesis
2
Hide details for Hauschild, Baumbach, BaumbachHauschild, Baumbach, Baumbach
2013Attachment IconPaving the Way for Automated Clinical Breath Analysis and Biomarker DetectionMiscellaneous
2012Attachment IconIntegrated statistical learning of metabolic ion mobility spectrometry profiles for pulmonary disease identification
In: Genetics and Molecular Research [11], 2733-2744
Electronic Journal Article
1
Hide details for Hauschild, Kopczynski, D'Addario, Baumbach, Rahmann, BaumbachHauschild, Kopczynski, D'Addario, Baumbach, Rahmann, Baumbach
2013Peak Detection Method Evaluation for Ion Mobility Spectrometry by using Machine Learning Approaches
In: Metabolites [3], 277-293
Electronic Journal Article
1
Hide details for Hauschild, Schneider, Pauling, Rupp, Jang, Baumbach, BaumbachHauschild, Schneider, Pauling, Rupp, Jang, Baumbach, Baumbach
2012Attachment IconComputational Methods for Metabolomic Data Analysis of Ion Mobility Spectrometry Data - Reviewing the State of the Art
In: Metabolites [2], 733-755
Electronic Journal Article
1
Hide details for Heckmann-Pohl, Bastian, Altmeier, AntesHeckmann-Pohl, Bastian, Altmeier, Antes
2006Improvement of the fungal enzyme pyranose 2-oxidase using protein engineering
In: Journal of Biotechnology [124], 26-40
Journal Article
2
Hide details for Heger, Thielen, Gilles, Obermeier, Lengauer, Kaiser, TrappHeger, Thielen, Gilles, Obermeier, Lengauer, Kaiser, Trapp
2012APOBEC3G/F a one possible driving source for co-receptor switch of the human immunodeficiency virus-1
In: Medical Microbiology and Immunology [201], 7-16
Journal Article
2011APOBEC3G/F as one possible driving force for co-receptor switch of the human immunodeficiency virus-1
In: Medical Microbiology and Immunology [201], 7-16
Journal Article
1
Hide details for Heil, Ludwig, Lichtenberg-Fraté, LengauerHeil, Ludwig, Lichtenberg-Fraté, Lengauer
2006Computational recognition of potassium channel sequences
In: Bioinformatics [13], 1562-1568
Journal Article
1
Hide details for Hessler, Zimmermann, Matter, Evers, Naumann, Lengauer, RareyHessler, Zimmermann, Matter, Evers, Naumann, Lengauer, Rarey
2005Multiple-Ligand-Based Virtual Screening: Methods and Applications of the MTree Approach
In: Journal of Medicinal Chemistry [48], 6575-6584
Journal Article
1
Hide details for Hindle, Rarey, Buning, LengauerHindle, Rarey, Buning, Lengauer
2002Flexible docking under pharmacophore type constraints
In: Journal of Computer-Aided Molecular Design [16], 129-149
Journal Article
1
Hide details for HoblerHobler
2006Docking of monosaccharids into the wild type and mutants of pyranose 2-oxidase
Universität des Saarlandes
Thesis - Bachelor thesis
1
Hide details for Hoffmann, Schnaible, Wefing, Albrecht, Hanisch, ZimmerHoffmann, Schnaible, Wefing, Albrecht, Hanisch, Zimmer
2002A new method for the fast solution of protein-3D-structures, combining experiments and bioinformatics
In: Coupling of Biological and Electronic Systems: Proceedings of the 2nd Caesarium, Bonn, 1-3 November 2000, 59-78
Proceedings Article
1
Hide details for Hofmann, Chung, Osbahr, Susser, Karey, Mihm, Welsch, Lötsch, Sarrazin, Zeuzem, HerrmannHofmann, Chung, Osbahr, Susser, Karey, Mihm, Welsch, Lötsch, Sarrazin, Zeuzem, Herrmann
2011Impact of ribavirin on HCV replicon RNA decline during treatment with interferon-α and the protease inhibitors boceprevir or telaprevir
In: Antiviral Therapy [16], 695-704
Journal Article
1
Hide details for Hofmann, Fernandez, Herrmann, Welsch, Mihm, Kronenberg, Feldmann, Spengler, Zeuzem, SarrazinHofmann, Fernandez, Herrmann, Welsch, Mihm, Kronenberg, Feldmann, Spengler, Zeuzem, Sarrazin
2007Somatic hypermutation and mRNA expression levels of the BCL-6 gene in patients with hepatitis C virus-associated lymphoproliferative diseases
In: Journal of Viral Hepatitis [14], 484-491
Journal Article
1
Hide details for Hofmann, Herrmann, Kronenberger, Merkwirth, Welsch, Lengauer, Zeuzem, SarrazinHofmann, Herrmann, Kronenberger, Merkwirth, Welsch, Lengauer, Zeuzem, Sarrazin
2004Association of HCV-related mixed cryoglobulinemia with specific mutational patterns of the HCV E2 protein and CD81 expression on peripheral B lymphocytes
In: Blood [104], 1228-1229
Journal Article
1
Hide details for Hofmann, Welsch, Takahashi, Miyajima, Mihm, Krick, Zeuzem, SarrazinHofmann, Welsch, Takahashi, Miyajima, Mihm, Krick, Zeuzem, Sarrazin
2007Identification and in silico characterization of a novel compound heterozygosty associated with hereditary aceruloplasminemia
In: Scandinavian Journal of Gastroenterology [42], 1088-1094
Journal Article
1
Hide details for HoinkaHoinka
2011Finding the Hairpin in the Haystack: Towards an High Throughput in Silico Pipeline for Aptamer Motif Identification using SELEX Data
Universität des Saarlandes
Thesis - Masters thesis
1
Hide details for Hornstein, Hoffmann, Alexa, Yamanaka, Müller, Jung, Rahnenführer, SchulzHornstein, Hoffmann, Alexa, Yamanaka, Müller, Jung, Rahnenführer, Schulz
2008Protein phosphatase and TRAIL receptor genes as new candidate tumor genes on chromosome 8p in prostate cancer
In: Cancer Genomics & Proteomics [5], 123-136
Journal Article
1
Hide details for HuthmacherHuthmacher
2006Decomposing Protein Networks Into
Domain-Domain Interactions
Eberhard Karls University Tübingen
Thesis - other
1
Hide details for IfrimIfrim
2005A Bayesian Learning Approach to Concept-Based Document Classification
Universität des Saarlandes
Thesis - Masters thesis
1
Hide details for ImmesbergerImmesberger
2005Attachment IconA Prefiltering Method to Speed up Protein
Structure Prediction
Universität des Saarlandes
Thesis - Bachelor thesis
1
Hide details for IvanovaIvanova
2011Comparison of methods for discovering genomic aberrations relevant for cancer
Universität des Saarlandes
Thesis - Masters thesis
1
Hide details for James, Das, Rahnenführer, AhmadJames, Das, Rahnenführer, Ahmad
2004Cellular and Molecular Characterization of Early and Late Retinal Stem Cells/Progenitors: Differential Regulation of Proliferation and Context Dependent Role of Notch Signaling
In: Journal of Neurobiology [61], 359-376
Journal Article
1
Hide details for James, Das, Rahnenführer, Leon, AhmadJames, Das, Rahnenführer, Leon, Ahmad
2003Identification of rat brahma (rBRM), a subunit of SWI/SNF chromatin remodeling complex: Involvement in the differentiation of retinal stem cells/progenitorsMiscellaneous
1
Hide details for James, Das, Zhao, Rahnenführer, AhmadJames, Das, Zhao, Rahnenführer, Ahmad
2004Identification of c-Kit receptor as a regulator of adult neural stem cells in the mammalian eye: interactions with Notch signaling
In: Developmental Biology [273], 87-105
Journal Article
1
Hide details for Janssen, RahnenführerJanssen, Rahnenführer
2003A hazard based approach to dependence tests for bivariate censored models
In: Mathematical Methods in Statistics [11], 297-322
Journal Article
1
Hide details for Jenkinson, Albrecht, Birney, Blankenburg, Down, Finn, Hermjakob, Hubbard, Jimenez, Jones, Kähäri, Kulesha, MacJenkinson, Albrecht, Birney, Blankenburg, Down, Finn, Hermjakob, Hubbard, Jimenez, Jones, Kähäri, Kulesha, Macías, Reeves, Prlić
2008Integrating biological data - the Distributed Annotation System
In: BMC Bioinformatics [9], S3.1-7
Journal Article
1
Hide details for JingJing
2011A comprehensive analysis of the illumina Infinium assay
Universität des Saarlandes
Thesis - Masters thesis
1
Hide details for JohannsenJohannsen
2010Random Combinatorial Structures and Randomized Search Heuristics
Universität des Saarlandes
Thesis - PhD thesis
1
Hide details for Jose, Betschieder, Ray, Lengauer, ZangenJose, Betschieder, Ray, Lengauer, Zangen
2003New inhibitors of human cathepsin G identified by surface display library screening and peptide-protein docking
In: 7th International Symposium on Pharmaceutical Sciences (ISOPS-7), 46-49
Proceedings Article
1
Hide details for JungJung
2006Yamada Analyzer - A tool for fast calculation of genomic attributes
Universität des Saarlandes
Thesis - Bachelor thesis
1
Hide details for JungeJunge
2011Unsupervised dissection of cancer types based on genomic, epigenomic and transciptomic features
Universität des Saarlandes
Thesis - Bachelor thesis
2
Hide details for KacprowskiKacprowski
2011Disease gene prioritization by combining network information and functional knowledge
Universität des Saarlandes
Thesis - Masters thesis
2010Analysis of protein complexes and tissue-spedific expression
Universität des Saarlandes
Thesis - Bachelor thesis
1
Hide details for Kacprowski, Doncheva, AlbrechtKacprowski, Doncheva, Albrecht
2013Attachment IconNetworkPrioritizer: a versatile tool for network-based prioritization of candidate disease genes or other molecules
In: Bioinformatics [29], 1471-1473
Journal Article
1
Hide details for Kämper, Apostolakis, LengauerKämper, Apostolakis, Lengauer
2002Docking of Bacterial Cell-Wall Fragments into Glycopeptide Antibiotics
In: From Genes to Drugs via Crystallography: 33rd crytallographic course at the E. Majorana Center, 49
Poster
3
Hide details for Kämper, Apostolakis, Rarey, Marian, LengauerKämper, Apostolakis, Rarey, Marian, Lengauer
2006Fully Automated Flexible Docking of Ligands into Flexible Synthetic Receptors Using Forward and Inverse Docking Strategies
In: Journal of Chemical Information and Modeling [46], 903-911
Journal Article
2001Docking of Ligands into Artificial ReceptorsMiscellaneous
2001Docking of Ligands into Artificial Receptors
In: Electronically Excited Molecules: Structure and Dynamics, 37th Symposium for Theoretical Chemistry, P76
Proceedings Article
1
Hide details for Kämper, Kaspar, LengauerKämper, Kaspar, Lengauer
2005Efficient conformational analysis of synthetic receptors with macrocyclic and fused ring systems
In: Synthetic Receptors 2005: Second World Congress on Synthetic Receptors, O4
Proceedings Article
3
Hide details for Kämper, LengauerKämper, Lengauer
2003ECLIPPSE: Environment for Chemical Library Inspection, Pre- and Postprocessing, and Screening Evaluation. User GuideManual
2003Virtual Screening for novel Urease Inhibitors
In: Proceedings of the International Workshop on New Approaches in Drug Design & Discovery, 39
Poster
2002Docking of Ligands into Molecular Tweezers and Molecular Clips
In: Workshop of the SFB 624 'Templates', ?-?
Poster
1
Hide details for Kämper, Rognan, LengauerKämper, Rognan, Lengauer
2007Lead Identification by Virtual Screening
In: Bioinformatics - From Genomes to Therapies 2. Getting at the Inner Workings: Molecular Interactions, 651-704
Part of a Book
1
Hide details for Kaiser, Boussaad, Lehmann, Däumer, Sing, Schmeisser, Wyen, FätkenheuerKaiser, Boussaad, Lehmann, Däumer, Sing, Schmeisser, Wyen, Fätkenheuer
2005Stable coreceptor usage of HIV-1 in patients with ongoing treatment failure on HAART
In: Proceedings of the 3rd European HIV Drug Resistance Workshop, -
Proceedings Article
1
Hide details for KalaghatgiKalaghatgi
2012A Phylodynamic Study of HIV Transmission Networks in Europe
Universität des Saarlandes
Thesis - Masters thesis
1
Hide details for Kalaghatgi, LawyerKalaghatgi, Lawyer
2013Inter-country mixing in HIV transmission clusters: a pan-European phylodynamics study
In: Abstract Book 11th European HIV & Hepatitis Workshop, 9
Poster
1
Hide details for Kalinina, Oberwinkler, Glass, Kräusslich, Russell, BriggsKalinina, Oberwinkler, Glass, Kräusslich, Russell, Briggs
2012Computational Identification of Novel Amino-Acid Interactions in HIV Gag via Correlated Evolution
In: PLoS ONE [7], e42468,1-e42468,5
Electronic Journal Article
1
Hide details for Kalinina, Pfeifer, LengauerKalinina, Pfeifer, Lengauer
2013Modelling binding between CCR5 and CXCR4 receptors and their ligands suggests the surface electrostatic potential of the co-receptor to be a key player in the HIV-1 tropism
In: Retrovirology [10], 130
Journal Article
1
Hide details for Kamp, Wolf, Bravo, Kraus, Krause, Neumann, Winskowsky, Thielen, Werner, SchnierleKamp, Wolf, Bravo, Kraus, Krause, Neumann, Winskowsky, Thielen, Werner, Schnierle
2010Decreased HIV diversity after allogeneic stem cell transplantation of an HIV-1 infected patient: a case report.
In: Virology Journal [7], 55,1-55,9
Electronic Journal Article
1
Hide details for Kamradt, Jung, Wahrheit, Tolosi, Rahnenführer, Schilling, Walker, Davis, Stöckle, Meltzer, WullichKamradt, Jung, Wahrheit, Tolosi, Rahnenführer, Schilling, Walker, Davis, Stöckle, Meltzer, Wullich
2007Detection of Novel Amplicons in Prostate Cancer by Comprehensive Genomic Profiling of Prostate Cancer Cell Lines Using Oligonucleotide-Based ArrayCGH
In: PLoS ONE [2], e769
Electronic Journal Article
2
Hide details for KasparKaspar
2006Automated conformational analysis of macrocyclic ring systems
Universität des Saarlandes
Thesis - Masters thesis
2005Attachment IconConformational Analysis of Macrocyclic Ring Systems
Universität des Saarlandes
Thesis - Bachelor thesis
1
Hide details for Ketter, Kim, Storck, Rahnenführer, Romeike, Steudel, Zang, HennKetter, Kim, Storck, Rahnenführer, Romeike, Steudel, Zang, Henn
2007Attachment IconHyperdiploidy defines a distinct cytogenetic entity of meningiomas
In: Journal of Neuro-Oncology [83], 213-221
Journal Article
1
Hide details for Ketter, Urbschat, Henn, Feiden, Beerenwinkel, Lengauer, Steudel, Zang, RahnenführerKetter, Urbschat, Henn, Feiden, Beerenwinkel, Lengauer, Steudel, Zang, Rahnenführer
2007Application of oncogenetic trees mixtures as a biostatistical model of the clonal cytogenetic evolution of meningiomas
In: International Journal of Cancer [121], 1473-1480
Journal Article
1
Hide details for KircherKircher
2007In silico analysis of microRNA genes on human chromosome 14 and mouse chromosome 12
Universität des Saarlandes
Thesis - Masters thesis
1
Hide details for Kircher, Bock, PaulsenKircher, Bock, Paulsen
2008Attachment IconStructural conservation versus functional divergence of maternally expressed microRNAs in the Dlk1/Gtl2 imprinting region
In: BMC Genomics [9], 346
Journal Article
1
Hide details for KlingenKlingen
2012Automatic Recombination Analysis Using Recoo and Mebitoo
Universität des Saarlandes
Thesis - Bachelor thesis
1
Hide details for Knoepfel, Di Giallonardoc, Däumer, Thielen, MetznerKnoepfel, Di Giallonardoc, Däumer, Thielen, Metzner
2011In-depth analysis of G-to-A hypermutation rate in HIV-1 env DNA induced by endogenous APOBEC3 proteins using massively parallel sequencing
In: Journal of Virological Methods [71], 329-338
Journal Article
2
Hide details for KönigKönig
2012Automatic detection of loss of heterozygosity in cancer
Universität des Saarlandes
Thesis - Masters thesis
2010Env-wide analysis of coreceptor determining sites and subtype-specific differences in HIV-1
Universität des Saarlandes
Thesis - Bachelor thesis
1
Hide details for Kono, Bozek, Domingues, Shioda, NakayamaKono, Bozek, Domingues, Shioda, Nakayama
2009Impact of a single amino acid in the variable region 2 of the Old World monkey TRIM5alpha SPRY (B30.2) domain on anti-human immunodeficiency virus type 2 activity
In: Virology [388], 160-168
Journal Article
1
Hide details for KorbelKorbel
2007Identification of Symmetries in Molecules and Complexes
Universität des Saarlandes
Thesis - Masters thesis
1
Hide details for KoserKoser
2012Reconstructing anecestral methylation states in phylogenetic trees
Universität des Saarlandes
Thesis - Masters thesis
1
Hide details for KrierKrier
2005Attachment IconMotif Search in Protein Sequences for Protein
Structure Prediction
Universität des Saarlandes
Thesis - Bachelor thesis
1
Hide details for Krol, Blom, Winnebald, Berhörster, Barnett, Goesmann, Baumbach, BeckerKrol, Blom, Winnebald, Berhörster, Barnett, Goesmann, Baumbach, Becker
2011RhizoRegNet - A database of rhizobial transcription factors and regulatory networks.
In: Journal of Biotechnology [155], 127-134
Journal Article
1
Hide details for Kuhn CuellarKuhn Cuellar
2010A probabilistic algorithm for matching protein structures - and its application to detecting functionally relevant patterns
Universität des Saarlandes
Thesis - Masters thesis
1
Hide details for Kumar, Sun, Vamathevan, Li, Ingraham, Palmer, Huang, BrownKumar, Sun, Vamathevan, Li, Ingraham, Palmer, Huang, Brown
2011Comparative Genomics of Klebsiella pneumoniae Strains with Different Antibiotic Resistance Profiles
In: Antimicrobial Agents and Chemotherapy [55], 4267-4276
Journal Article
1
Hide details for KunertKunert
2011Maximal Common Subgraph DAGs: Theory and Application to Virtual Screening in Drug Development
Universität des Saarlandes
Thesis - PhD thesis
1
Hide details for Kupfer, Sing, Schüffler, Hall, Kurz, McKeown, Schneweis, Eberl, Oldenburg, Brackmann, Rockstroh, Spengler, DäuKupfer, Sing, Schüffler, Hall, Kurz, McKeown, Schneweis, Eberl, Oldenburg, Brackmann, Rockstroh, Spengler, Däumer, Kaiser, Lengauer, Matz
2007Fifteen years of env C2V3C3 evolution in six individuals clonally infected with human immunodeficiency virus type 1
In: Journal of Medical Virology [79], 1629-1639
Journal Article
1
Hide details for Kuroishi, Bozek, Shioda, NakayamaKuroishi, Bozek, Shioda, Nakayama
2010A single amino acid substitution of the human immunodeficiency virus type 1 capsid protein affects viral sensitivity to TRIM5 alpha.
In: Retrovirology [7], 58,1-58,10
Electronic Journal Article
1
Hide details for Lange, Roomp, Dragan, Nattermann, Michalk, Spengler, Weich, Lengauer, Zeuzem, Berg, SarrazinLange, Roomp, Dragan, Nattermann, Michalk, Spengler, Weich, Lengauer, Zeuzem, Berg, Sarrazin
2010HLA class I allele associations with HCV genetic variants in patients with chronic HCV genotypes 1a or 1b infection
In: Journal of Hepatology [53], 1022-1028
Journal Article
1
Hide details for LawyerLawyer
2014COMET: Adaptive context-based modeling for ultrafast HIV-1 subtype identification.
In: Nucleic Acids Research [42], e144
Journal Article
1
Hide details for Lawyer, Altmann, Thielen, Zazzi, Sönnerborg, LengauerLawyer, Altmann, Thielen, Zazzi, Sönnerborg, Lengauer
2011HIV-1 mutational pathways under multidrug therapy
In: AIDS Research and Therapy [8], 1-13
Journal Article
1
Hide details for Lawyer, Ferkingstad, Nesvåg, Varnäs, AgartzLawyer, Ferkingstad, Nesvåg, Varnäs, Agartz
2009Local and covariate-modulated false discovery rates applied in neuroimaging
In: NeuroImage [47], 213-219
Journal Article
1
Hide details for Lawyer, Nesvåg, Varnäs, Okugawa, AgartzLawyer, Nesvåg, Varnäs, Okugawa, Agartz
2009Grey and white matter proportional relationships in the cerebellar vermis altered in schizophrenia
In: Cerebellum [8], 52-60
Journal Article
1
Hide details for Lawyer, Schülter, Kaiser, Reuter, Oette, LengauerLawyer, Schülter, Kaiser, Reuter, Oette, Lengauer
2012Attachment IconEndogenous or exogenous spreading of HIV-1 in Nordrhein-Westfalen, Germany, investigated by phylodynamic analysis of the RESINA Study cohort
In: Medical Microbiology and Immunology [201], 259-269
Journal Article
1
Hide details for Lehmann, Däumer, Bousaad, Sing, Beerenwinkel, Lengauer, Schmeisser, Wyen, Fätkenheuer, KaiserLehmann, Däumer, Bousaad, Sing, Beerenwinkel, Lengauer, Schmeisser, Wyen, Fätkenheuer, Kaiser
2006Stable coreceptor usage of HIV in patients with ongoing treatment failure on HAART
In: Journal of Clinical Virology [37], 300-304
Journal Article
10
Hide details for LengauerLengauer
2012Bioinformatical Assistance of Selecting Anti-HIV Therapies: Where Do We Stand?
In: Intervirology [55], 108-112
Journal Article
2007Bioinformatik
In: Technologiefüher - Grundlagen, Anwendungen, Trends, 4
Part of a Book
2007Future Trends
In: Bioinformatics - From Genomes to Therapies 3. The Holy Grail: Molecular Function, 1651-1687
Part of a Book
2007Introduction
In: Bioinformatics - From Genomes to Therapies 1. The Building Blocks: Molecular Sequences and Structures, 1-24
Part of a Book
2007Strategiekonzept "Molekulare Bioinformatik"
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2003Analyzing resistance phenomena in HIV with bioinformatics methods
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2001Bioinformatik an der Schwelle zur postgenomischen Ära
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2011Computermodelle in der Wissenschaft - zwischen Analyse, Vorhersage und SuggestionBook
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2012Computational Biology
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2005Clinical significance of in vitro replication-enhancing mutations of the hepatitis C virus (HCV) replicon in patients with chronic HCV infection.
In: Journal of Infectious Diseases [192], 1710-1719
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2009Bioinformatische Unterstützung der Auswahl von HIV Therapien
In: Informatik Spektrum [32], 320-331
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2010Chasing the AIDS Virus
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2001Geno2pheno: a new machine learning approach to predicting phenotypic drug resistance from genotype
In: Antiviral Therapy [6], 104
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2012Managing drug resistance in cancer: lessons from HIV therapy
In: Nature Reviews Cancer [12], 494-501
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2006Analysis and prediction of protein-protein-interaction types
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2009Computerjagd auf das AIDSVIRUS
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2004Novel technologies for virtual screening
In: Drug Discovery Today [9], 27-34
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2002Proceedings of the European Conference on Computational Biology (ECCB 2002)Proceedings
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2005Automatic Generation of complementary descriptors with molecular graph networks
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2007European Journal of Medical ResearchJournal
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2007Proceedings ISMB2007Proceedings
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2007Bioinformatics prediction of HIV coreceptor usage
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2001Proceedings of the 5th Annual Conference on Research in Computational Molecular Biology (RECOMB2001)Book
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2003Combinatorial Optimization Techniques for Three-Dimensional Arrangement Problems
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2009Resistenzbestimmung
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2006Bioinformatics-assisted anti-HIV therapy
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2013Probabilistic error correction for RNA sequencing
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2002An Extended Set of Haar-like Features for Rapid Object Detection
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2008Theoretical and Experimental Evaluation of a CYP106A2 Low Homology Model and Production of Mutants with Changed Activity and Selectivity of Hydroxylation
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2013Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis
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2007Attachment IconThe human genomic melting map
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2010Identifying discriminative motifs for molecular function of proteins
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2007Current V3 genotyping algorithms are inadequate for predicting X4 co-receptor usage in clinical isolates
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2008Novel Aldosterone Synthase Inhibitors with Extended Carbocyclic Skeleton by a Combined Ligand-Based and Structure-Based Drug Design Approach
In: Journal of Medical Chemistry [51], 6138-6149
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2010Processing of high-throughput DNA methylation data
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2011BiQ Analyzer HT: locus-specific analysis of DNA methylation by high-throughput bisulfite sequencing
In: Nucleic Acids Research [39], W551-W556
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2009In Silico Models for the Prediction of Metabolism by Cytochrome P450 Enzymes
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1999Mutations in the ABC1 gene in familial HDL deficiency with defective cholesterol efflux
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2014MIMA - A software for analyte identification in MCC/IMS chromatograms by mapping accompanying GC/MS measurements
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2008Analysis of recombination in Molecular Sequence Data
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2006Recco: recombination analysis using cost optimization
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2002A Fast Method for Training Support Vector Machines With a Very Large Set of Linear Features
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2007Attachment IconComparative Analysis of Protein Structure Alignments
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2010Population-based V3 genotypic tropism assay: a retrospective analysis using screening samples from the A4001029 and MOTIVATE studies
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2009The role of genomics in tracking the evolution of influenza A virus
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2005Identification of functionally important regions in cytochrome P450 systems and a systematic analysis of various CYP P450 homology models
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2012Erosion of dosage compensation impacts human iPSC disease modeling
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2004Finite iteration DT-CNN - new design and operation principles
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2004Ensemble methods for classification in cheminformatics
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2003Attachment IconStochastic Gradient Descent Training of Ensembles of DT-CNN Classifiers for Digit Recognition
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2009Clinical relevance of the 2'-5'-oligoadenylate synthetase/RNase L system for treatment response in chronic hepatitis C
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2006Amino acid variations in hepatitis C virus p7 and sensitivity to antiviral combination therapy with amantadine in chronic hepatitis C
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2010Effect of ribavirin on the frequency of RNAse L cleavage sites within the hepatitis C viral genome
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2012DNA methylation biomarkers in cancer: Progress towards clinical implementation
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2007Attachment IconOptimization of Quantitative MGMT Promoter Methylation Analysis Using Pyrosequencing and Combined Bisulfite Restriction Analysis
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2008Improved detection of X4 virus by V3 genotyping: application to plasma RNA and proviral DNA
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2011clusterMaker: A Multi-algorithm Clustering Plugin for Cytoscape
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2009Attachment IconFunctional Analysis of a Potassium-Chloride Co-Transporter 3 (SLC12A6) Promoter Polymorphism Leading to an Additional DNA Methylation Site
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2012Extracting pathways from biological networks incorporating omics data, introducing a webinterface for KeyPathwayMiner
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2009Assessing Antibody Neutralization of HIV-1 as an Initial Step in the Search for gp160-based Immunogens
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2008Inferring virological response to antiretroviral combination therapy based on past treatment lines
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2007Using Shape Retrieval Techniques for Identifying Similar Protein Binding Sites
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2011DIDO: a disease-determinants ontology from web sources
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2013High frequency of complex mutational patterns in lamivudine resistant hepatitis B virus isolates
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2006A Fully Computational Model for Predicting Percutaneous Drug Absorption
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2006Prediction of percutaneous drug absorption
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2005Attachment IconGenerating Molecular Hashcodes for
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2002Expression and Functional Analyses of Novel Mutations ot ATP-Binding Cassette Transporter-1 in Japanese Patients with High-Density Lipoprotein Deficiency
In: Biochemical and Biophysical Research Communications [290], 713-721
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2008Determination of HIV-1 co-receptor usage in German patients – comparison of genotypic methods with the TROFILE® phenotypic assay
In: Abstracts of the Ninth International Congress on Drug Therapy in HIV Infection, 123
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2012HIV2EU: supporting standardized HIV-2 drug resistance interpretation in Europe
In: Journal of the International AIDS Society, 135
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2012HIV-GRADE: A Publicly Available, Rules-Based Drug Resistance Interpretation Algorithm Integrating Bioinformatic Knowledge
In: Intervirology [55], 102-107
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2008Determination of HIV-1 coreceptor usage in German patients - comparison of genotypic methods with the TROFILE phenotypic assay
In: Antiviral Therapy, A112
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2004Arby: Automatic protein structure prediction using profile-profile alignment and confidence measures
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2012Efficacy of antiretroviral therapy switch in HIV-infected patients: A 10-year analysis of the EuResist cohort
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2003Lactam hydrolysis catalyzed by mononuclear metallo-beta-lactamases: a density functional study
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2013Genome Signature based Sequence Comparison for Taxonomic Assignment and tree inference
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2012On the trail of EHEC/EAEC - unraveling the gene regulatory networks of human pathogenic Escherichia coli bacteria
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2012CoryneRegNet 6.0 - Updated database content, new analysis methods and novel features focusing on community demands
In: Nucleic Acids Research [40], D610-D614
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2003Parallel "go with the winners algorithms" in Distributed Memory Models
In: Journal of Parallel and Distributed Processing [63], 801-814
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2010Finding local similarities in gene expression patterns between partially reprogrammed cells and know cell types using a module network approach
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2008Attachment IconSemi-Supervised Learning for Predicting Anti-HIV Drug Resistance
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2006Development of a fast
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2013Association Between HIV-1 Coreceptor Usage and Resistance to Some Broadly Neutralizing Antibodies
In: Proceedings of the AIDS Vaccine Conference 2013, A-1-A-208
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2012Improving coreceptor usage prediction in the clinic using hints from next generation sequencing data
In: Bioinformatics [28], i589-i595
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2012Attachment IconImproving HIV coreceptor usage prediction in the clinic using hints from next-generation sequencing data
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2013HIV-1 fitness landscape models for indinavir treatment pressure using observed evolution in longitudinal sequence data are predictive for treatment failure
In: Infection, Genetics and Evolution [19], 349–360
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2009Probabilistic disease gene prioritization
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2011A Computational Method for Predicting First-Line Antiretroviral Therapy Success
In: Abstract Book. 9th Workshop on HIV & Hepatitis Treatment Strategies & Antiviral Drug Resistance, 94
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2012Characterization of HIV-1 Gag Subtype C
In: Abstract Book. 9th Workshop on HIV \& Hepatitis Treatment Strategies \& Antiviral Drug Resistance, 40-41
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3
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2014Simulation of Sanger-sequencing errors in the context of genotypic tropism determination
In: Antiviral Therapy, A81
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2013Effects of sequencing errors on geno2pheno[coreceptor] predictions
In: Abstract Book 11th European Meeting on HIV & Hepatitis, 23-24
Poster
2013In silico analysis of the effects of sequencing errors on geno2pheno[coreceptor]
In: Abstract Book of the International Workshop on HIV&Hepatitis Virus, A142
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3
Hide details for Pironti, Pfeifer, Kaiser, Walter, LengauerPironti, Pfeifer, Kaiser, Walter, Lengauer
2014Accurate prediction of drug-exposure without using established drug-resistance mutations
In: Antiviral Therapy, A75
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2014Improved HIV-1 drug-exposure reconstruction with linear support vector machines
In: Reviews in Antiviral Therapy & Infectious Diseases, 67
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2014Improved therapy-success prediction with GSS estimated from clinical HIV-1 sequences
In: Abstract Supplement of the HIV Drug Therapy Glasgow Congress 2014, 155
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2
Hide details for Pironti, Pfeifer, LengauerPironti, Pfeifer, Lengauer
2014Accurate prediction of drug-exposure without using established drug-resistance mutations
In: Antiviral Therapy, A75
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2014Improved HIV-1 drug-exposure reconstruction with linear support vector machines
In: Reviews in Antiviral Therapy & Infectious Diseases, 67
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2014Simulation of Sanger-sequencing errors in the context of genotypic tropism determination
In: Antiviral Therapy, A81
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2006Attachment IconMutations in the MutSalpha interaction interface of MLH1 can abolish DNA mismatch repair
In: Nucleic Acids Research [34], 6574-6586
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2004WILMA-automated annotation of protein sequences
In: Bioinformatics [20], 127-128
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2009Investigation of expert rule bases, logistic regression, and non-linear machine learning techniques for predicting response to antiretroviral treatment
In: Antiviral Therapy [14], 433-442
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2010Antiretroviral Therapy Optimisation without Genotype Resistance Testing: A Perspective on Treatment History Based Models
In: PLoS ONE [5], e13753,1-e13753,8
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2013A large-scale evaluation of computational protein function prediction
In: Nature Methods [10], 221-227
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2006Statistical methods for the biological interpretation of genome-wide measurements
Universität des Saarlandes
Thesis - Habilitation thesis
2005Clustering algorithms and other exploratory methods for microarray data analysis
In: Methods of Information in Medicine [44], 444-448
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2005Image analysis for cDNA microarrays
In: Methods of Information in Medicine [44], 405-407
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2003Efficient Clustering Methods for Tumor Classification with Microarrays
In: Proceedings of the 26th Annual Conference of the Gesellschaft für Klassifikation, 670-679
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2003On preferences of general two-sided tests with applications to Kolmogorov-Smirnov-type tests
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2003Statistical Inference for Clustering Microarrays
In: Proceedings of the MSRI Workshop: Nonlinear Estimation and Classification, 323-332
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2002Hybrid clustering for microarray analysis combining intensity and shape features
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2002Multivariate permutation tests for the k-sample problem with clustered data
In: Computational Statistics [17], 165-184
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2005Estimating cancer survival and clinical outcome based on genetic tumor progression scores
In: Bioinformatics [21], 2438-2446
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2004Hybrid clustering for microarray image analysis combining intensity and shape features
In: BMC Bioinformatics [5], 1-11
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2003Comparative quality analyses for hybrid clustering of microarray images
In: Proceedings of the Sventh Annual International Conference on Computational Biology, -
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2002Unsupervised technique for robust target separation and analysis of DNA microarray spots through adaptive pixel clustering
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2004Calculating the statistical significance of changes in pathway activity from gene expression data
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2003Cost-effective screening for differentially expressed genes in microarray experiments based on normal mixtures
In: Austrian Journal of Statistics [32], 225-238
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2007Analysis of Expression Data: Classification of genes
In: Bioinformatics - From Genomes to Therapies 2. Getting at the Inner Workings: Molecular Interactions, 993-1021
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2005An integrative approach to gain insights into the cellular function of human ataxin-2
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2005Ataxin-2 and huntingtin interact with endophilin-A complexes to function in plastin-associated pathways
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2012Novel Approaches to the Integration and Analysis of Systems Biology
Universität des Saarlandes
Thesis - PhD thesis
2010Tutorial Cytoscape
In: Bioinformática: Aplicaciones a la genómica y proteómica, 73-98
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2004Evolucion de la Evolucionalidad
In: Biologos lejos del equilibrio: Nuevas metaforas evolutivas, 59-87
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2004Hacia una comprension de la accion de la recombinacion genetica y la mutacion en el origen de la variacion fenotipica, mediante el analisis de la computacion evolutiva
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2010Finding scaffold proteins in interactomes
In: Trends in Cell Biology [20], 2-4
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2000GenLab: Laboratorio virtual de genetica
In: Acta Biologica Colombiana [5], 45-48
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2012Novel search method for the discovery of functional relationships
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2007Computational analysis of human protein interaction networks
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2011Analysis of quality raw data of second generation sequencers with Quality Assessment Software
In: BMC Research Notes [4], 130,1-130,6
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2006Docking studies to investigate the effect of correlated mutations in the HIV-Protease on the drug resistance of HIV
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2011Recruitment and activation of a lipid kinase by hepatitis C virus NS5A is essential for integrity of the membranous replication compartment
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2012Attachment IconLow k-shells identify bridge elements critical to disease flow in small-world networks
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2011Estimating and Using the Uncertainty in the Phenotypic Resistance Assay of the Hepatitis B Virus to Improve IC-50 Prediction from Genotype
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2012Risk factors associated with older age in treatment-naive HIV-positive patients
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2011Attachment IconErratum to: Prevalence and characteristics of hepatitis B and C virus infections in treatment-naïve HIV-infected patients.
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2011Prevalence and characteristics of hepatitis B and C virus infections in treatment-naïve HIV-infected patients
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2010Attachment IconHepatitis B virus reverse transcriptase sequence variant database for sequence analysis and mutation discovery
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2013Density Parameter Estimation for Finding Clusters of Homologous Proteins - Tracing Actinobacterial Pathogenicity Life Styles
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2012How Little Do We Actually Know? - On the Size of Gene Regulatory Networks.
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2007Evolution of Drug Resistance in HIV
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2010Predicting MHC class I epitopes in large datasets
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2006Arevir: A Secure Platform for Designing Personalized Antiretroviral Therapies Against HIV
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2011Predicting interactions between T cell receptors and MHC-peptide complexes
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2009Intensive blood glucose control is safe and effective in diabetic cats using home monitoring and treatment with glargine
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2008Selecting anti-HIV therapies based on a variety of genomic and clinical factors
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2008Sustaining lamivudine/emtricitabine, abacavir, zidovudine or atazanavir from a previous treatment shows a clinical benefit
In: Antiviral Therapy, A86
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2012Paving the future: finding suitable ISMB venues
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2011Evidence for Reductive Genome Evolution and Lateral Acquisition of Virulence Functions in two Corynebacterium pseudotuberculosis strains
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2010Reaction graph kernels predict EC numbers of unknown enzymatic reactions in plant secondary metabolism
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2006A network-based analysis of polyanion-binding proteins utilizing yeast protein arrays
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2008Structural Descriptors for the Analysis of Protein Structure, Function, and Evolution
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2004Local sequence-structure relationships in proteins
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2008Computational analysis of covariation and interactions between HIV-1 reverse transcriptase and Integrase
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2008Structural descriptors of protein-protein binding sites
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2006Local protein structure prediction using discriminative models
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2013A Prognostic DNA Methylation Signature for Stage I Non-Small-Cell Lung Cancer
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2011A singular value decomposition approach for improved taxonomy classification of biological sequences
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2005Clinical significance of in vitro replication-enhancing mutations of the hepatitis C virus (HCV) replicon in patients with chronic HCV infection
In: The Journal of Infectious Diseases [192], 1710-1719
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2001Automated Layout Generation and Wiring Area Estimation for 3D Electronic Modules
In: ASME Journal of Machanical Design [123], 330-336
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2007Prediction of Domain and Motif Interactions from Protein Networks
Universität des Saarlandes
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2013Sensitive detection of viral transcripts in human tumor transcriptomes
In: PLOS Computational Biology [9], xx
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2008An integrative approach for predicting interactions of protein regions
In: Bioinformatics [24], i35-i41
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2011Inferring physical protein contacts from large-scale purification data of protein complexes
In: Molecular & Cellular Proteomics [10], M110.004929,1-M110.004929,15
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2007Identification of PatL1, a human homolog to yeast P body component Pat1
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2010Attachment IconOntology-based Similarity Measures and their Application in Bioinformatics
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2005A Global Approach to Comparative Genomics: Comparison of Functional Annotation over the Taxonomic Tree
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2004Attachment IconAutomated Differential Analysis of Proteomes
Universität des Saarlandes
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2010FunSimMat update: new features for exploring functional similarity
In: Nucleic Acids Research [38], D244-D248
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2008Attachment IconFunSimMat: a comprehensive functional similarity database
In: Nucleic Acids Research [36], D434-D439
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2006Attachment IconA new measure for functional similarity of gene products based on Gene Ontology
In: BMC Bioinformatics [7], 1-16
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2007Attachment IconFunctional evaluation of domain-domain interactions and human protein interaction networks
In: Bioinformatics [23], 859-865
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2006Functional evaluation of domain-domain interactions and human protein interaction networks
In: German Conference on Bioinformatics (GCB 2006), 115-126
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2010Improving disease gene prioritization using the semantic similarity of Gene Ontology terms
In: Bioinformatics [26], i561-i567
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2007Attachment IconGOTax: investigating biological processes and biochemical activities along the taxonomic tree
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2013An Integrative Clinical Database and Diagnostics Platform for Biomarker Identification and Analysis in Ion Mobility Spectra of Human Exhaled Air
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2005Genetics of Crohn disease, an archetypal inflammatory barrier disease
In: Nature Reviews Genetics [6], 376-388
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2008MethMarker – A toolkit for design, optimization and validation of DNA methylation biomarkers for cancer diagnosis and therapy optimization
Universität des Saarlandes
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2009Attachment IconMethMarker: User-friendly design and optimization of gene-specific DNA methylation assays
In: Genome Biology [10], R105:1-R105:10
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2012Etravirine in protease inhibitor-free antiretroviral combination therapies
In: Journal of the International AIDS Society, 155-156
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1
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2011HIV prevalence and route of transmission in Turkish immigrants
living in North-Rhine Westphalia, Germany
In: Medical Microbiology and Immunology [200], 219-223
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2007Attachment IconFactor interaction analysis for chromosome 8 and DNA methylation alterations highlights innate immune response suppression and cytoskeletal changes in prostate cancer
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2013Reconstructing dynamic microRNA-regulated interaction networks
In: Proceedings of the National Academy of Sciences of the United States [110], 15686–15691
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2011High Concordance between the Position-Specific Scoring Matrix and Geno2pheno Algorithms for Genotypic Interpretation of HIV-1 Tropism: V3 Length as the Major Cause of Disagreement
In: Journal of Clinical Microbiology [49], 3380-3382
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2012Multi-scale computational modeling of developmental biology
In: Bioinformatics [28], 2022-2028
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2011Protease Inhibitor-Resistant Hepatitis C Virus Mutants With Reduced Fitness From Impaired Production of Infectious Virus
In: Gastroenterology [140], 667-675
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2009Evolution of raltegravir resistance during therapy
In: Journal of antimicrobial chemotherapy [64], 25-32
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2012Optimisation of baseline genotypic testing for safe and efficient maraviroc administration
In: Journal of the International AIDS Society, 101-102
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2011Prediction of HIV-1 coreceptor usage (tropism) by sequence analysis using a genotypic approach
In: Journal of Visualized Experiments [58], e3264,1-e3264,9
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2007Attachment IconGenotypic coreceptor analysis.
In: European Journal of Medical Research [12], 453-462
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2008Genotypic Analysis of HIV Co-Receptor Usage
In: Entry Inhibitoren - Neue Formen der HIV-Therapie, 31-39
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2013Comparative genome-wide DNA methylation analysis of colorectal tumor and matched human tissue
In: Epigenetics [7], 1355-1367
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2008Model-Based Anti HIV Therapy
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2004Learning localized rule mixtures by maximizing the area under the ROC curve, with an application to the prediction of HIV-1 coreceptor usage
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2007Attachment IconMutagenetic tree Fisher kernel improves prediction of HIV drug resistance from viral genotype
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2005Geno2pheno[coreceptor]: a tool for predicting coreceptor usage from genotype and for monitoring coreceptor-associated sequence alterations
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2004Learning mixtures of localized rules by maximizing the area under the ROC curve
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2007Predicting HIV coreceptor usage on the basis of genetic and clinical covariates
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2006ROCR: Visualizing classifier performance in R
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2005Characterization of novel HIV Drug Resistance Mutations using clustering, multidimensional scaling and SVM-based feature ranking
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2005Computational prediction of MHC-peptide interactions
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2007Attachment IconDetermining human immunodeficiency virus coreceptor use in a clinical setting: Degree of correlation between two phenotypic assays and a bioinformatic model
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2014Current breathomics – A review on data pre-processing techniques and machine learning in metabolomics breath analysisUnpublished/Draft
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2007Protein Fold Recognition Based on Distant Homologs
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2007Moment invariants as shape recognition technique for comparing protein binding sites
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2006Improving the quality of protein structure models by selecting from alignment alternatives
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2002Confidence measures for protein fold recognition
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2009Predicting drug susceptibility of non-small cell lung cancers based on genetic lesions
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2010Network analysis of viral host factors
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2006Flexible Docking of Ligands into Synthetic Receptors Using a Two-Sided Incremental Construction Algorithm
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2007Combined similarity and QSPR virtual screening for guest molecules of $\beta$-cyclodextrin
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2013Assessment of transcript reconstruction methods for RNA-seq
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2010History Based HIV Therapy Outcome Prediction
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2008Protein Surface Remeshing and Characterisation Using Morse-Smale Complexes
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2004Genetic variation in DLG5 is associated with inflammatory bowel disease
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2011Role of hepatitis B virus genetic barrier in drug-resistance and immune-escape development
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2005Additional Mutations in HIV-1 Reverse Transcriptase are Involved in the Highly Ordered Regulation of NRTI Resistance
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2005A highly ordered network of HIV-1 RT mutations regulates the continuous escape from antiviral drugs
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2011Role of hepatitis B virus genetic barrier in drug-resistance and immune-escape development
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2006Involvement of novel HIV-1 reverse transcriptase mutations in the regulation of resistance to nucleoside inhibitors
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2010Genotypic determination of HIV-1 tropism in the clinical setting
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2010Improved detection of CXCR4-using HIV by V3 genotyping: application of population-based and "deep" sequencing to plasma RNA and proviral DNA
In: Journal of Acquired Immune Deficiency Syndromes [54], 506-510
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2011Deep V3 sequencing for HIV type 1 tropism in treatment-naive patients: a reanalysis of the MERIT trial of maraviroc.
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2006Resistance proteins: molecular switches of plant defence
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2008Development of Computational Methods for Metabolic Network Analysis based on Metabolomics Data
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2005Towards computational analysis of metabolic profiling data for protein function prediction.
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2004Computational Methods For Metabolite Screening
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2004Computational Methods For Metabolite Screening
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2005Computational Methods for Protein Function Prediction using Metabolomics Data
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2003Towards cellular function through metabolite screening
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2006Development of Computational Methods for Analysis of Metabolic Profiling Data
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2003Software tool for automated processing of 13C labeling data from mass spectrometry data
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2006Mutations in the NB-ARC domain of I-2 that impair ATP hydrolysis cause autoactivation
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2011Genotypic Analysis of HIV-1 Coreceptor Usage
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2006Prediction of linear B-cell epitopes and MHC class II binding peptides
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2009Estimating evolutionary pathways to 7CXCR4 usage from cross-sectional data
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2008Improved genotypic prediction of HIV-1 coreceptor usage by incorporating V2 loop sequence variation
In: Antiviral Therapy, A100
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2008Improving HIV-1 coreceptor usage prediction from genotype with regions outside of V3
In: Reviews in Antiviral Therapy, 81-82
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In: Intervirology [55], 113-117
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2010Mutations within GP41 are correlated with coreceptor tropism but do not substantially improve coreceptor usage prediction
In: Reviews in Antiviral Therapy & Infectious Diseases, 47-47
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2011Mutations in gp41 are correlated with coreceptor tropism but do not improve prediction methods substantially
In: Antiviral Therapy [16], 319-328
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2009Performance of genotypic coreceptor measurement using geno2pheno[coreceptor] in B- and non-B HIV subtypes in a large cohort of therapy-experienced patients in Germany
In: Reviews in Antiviral Therapy, 99-99
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2010Improved prediction of HIV-1 coreceptor usage with sequence information from the second hypervariable loop of gp120
In: Journal of Infectious Diseases [202], 1435-1443
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2004Proceedings Twelfth International Conference on Intelligent Systems for Molecular Biology/Third European Conference on Computional Biology 2004 (ISMB/ECCB 2004)Proceedings
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2012Finding Regions of Aberrant DNA Copy Number Associated With Tumor Phenotype
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2006Analysis of Array CGH Data for the Estimation of Genetic Tumor Progression
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2006Attachment IconEditorial: Selection of papers of the German Conference of Bioinformatics (GCB) 2005
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2004Analysis of protein binding pocket flexibility
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2007Attachment IconThe implications of alternative splicing in the ENCODE protein complement
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2009Dynamics of NRTI resistance mutations during therapy interruption
In: AIDS Research and Human Retroviruses [25], 57-64
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2005Synthesis and Evaluation of Pyridylmethylene-tetrahydronaphthalenes and -indanes: Potent and Selective Inhibitors of Aldosterone Synthase (CYP11B2)
In: Journal of Medicinal Chemistry [48], 4489-4490
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In: Journal of Medicinal Chemistry [48], 1796-1805
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2005Sarcoidosis is associated with a truncating splice site mutation in BTNL2
In: Nature Genetics [37], 357-364
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2005A new CARD15 mutation in Blau syndrome
In: European Journal of Human Genetics [13], 742-747
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2008Transcomplementation, but not physical association of the CC-NB-ARC and LRR domains of tomato R protein Mi-1.2 is altered by mutations in the ARC2 subdomain
In: Molecular Plant [1], 401-410
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2008Structure-function analysis of the NB-ARC domain of plant disease resistance proteins
In: Journal of Experimental Botany [59], 1383-1397
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2006Metabolic high- content screening of Saccharomyces cerevisiae reveals superior performance of single gene deletion strains
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2008Relevance of HIV gag cleavage site mutations in failures of protease inhibitor therapies
In: Antiviral Therapy, A53
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2006Compensatory mutations at the HIV cleavage sites p7/p1 and p1/p6-gag in therapy-naive and therapy-experienced patients
In: Antiviral Therapy [11], 879-887
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2007Automated generation of pharmacophore type constraints to improve FlexX docking
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2007EuResist: exploration of multiple modeling techniques for prediction of response to treatment
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2006NOXclass: prediction of protein-protein interaction types
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2001Centralization: A biologically sensible method for the normalization of gene expression data
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2003Microarrays: How many do you need?
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2002Microarrays: How Many Do You Need?
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2013Charting a dynamic DNA methylation landscape of the human genome
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2011Genomic distribution and inter-sample variation of non-CpG methylation across human cell types
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2006Functional Site Scaffolds
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