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Author, Editor(s)

Author(s):

Takken, Frank L. W.
Albrecht, Mario
Tameling, Wladimir I.

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Not MPG Author(s):

Takken, Frank L.
Tameling, Wladimir I.

BibTeX cite key*:

Albrecht2006c

Title

Title*:

Resistance proteins: molecular switches of plant defence

Journal

Journal Title*:

Current Opinion in Plant Biology

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Download URL
for the article:

http://www.aseanbiotechnology.info/Abstract/21019430.pdf

Language:

English

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Name:


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Address:


ISSN:


Vol, No, pp, Date

Volume*:

9

Number:

4

Publishing Date:

2006

Pages*:

383-390

Number of
VG Pages:


Page Start:


Page End:


Sequence Number:


DOI:


Note, Abstract, ©

Note:


(LaTeX) Abstract:


Specificity of the plant innate immune system is often conferred by resistance (R) proteins. Most R proteins contain leucine-rich repeats (LRRs), a central nucleotide-binding site (NBS) and a variable amino-terminal domain. The LRRs are mainly involved in recognition, whereas the amino-terminal domain determines signalling specificity. The NBS forms part of a nucleotide binding (NB)-ARC domain that presumably functions as a molecular switch. The conserved nature of NB-ARC proteins makes it possible to map mutations of R protein residues onto the crystal structures of related NB-ARC proteins, providing hypotheses for the functional roles of these residues. A functional model emerges in which the LRRs control the molecular state of the NB-ARC domain. Pathogen recognition triggers nucleotide-dependent conformational changes that might induce oligomerisation, thereby providing a scaffold for activation of downstream signalling components.

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MPG Unit:

Max-Planck-Institut für Informatik



MPG Subunit:

Computational Biology and Applied Algorithmics

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BibTeX Entry:

@ARTICLE{Albrecht2006c,
AUTHOR = {Takken, Frank L. W. and Albrecht, Mario and Tameling, Wladimir I.},
TITLE = {Resistance proteins: molecular switches of plant defence},
JOURNAL = {Current Opinion in Plant Biology},
YEAR = {2006},
NUMBER = {4},
VOLUME = {9},
PAGES = {383--390},
}


Entry last modified by Uwe Brahm, 07/11/2007
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Editor(s)
Mario Albrecht
Created
03/23/2006 07:42:47 PM
Revisions
4.
3.
2.
1.
0.
Editor(s)
Uwe Brahm
Christine Kiesel
Christine Kiesel
Mario Albrecht
Mario Albrecht
Edit Dates
2007-07-11 12:32:31
08.05.2007 21:57:51
22.02.2007 16:18:27
10/05/2006 05:15:25 PM
23.03.2006 19:42:47