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Author, Editor(s)

Author(s):

Roomp, Kirsten
Beerenwinkel, Niko
Sing, Tobias
Schülter, Eugen
Büch, Joachim
Sierra-Aragon, Saleta
Däumer, Martin
Hoffmann, Daniel
Kaiser, Rolf
Lengauer, Thomas
Selbig, Joachim

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Not MPG Author(s):

Schülter, Eugen
Sierra-Aragon, Saleta
Däumer, Martin
Hoffmann, Daniel
Kaiser, Rolf
Selbig, Joachim

BibTeX cite key*:

Roomp2006

Title

Title*:

Arevir: A Secure Platform for Designing Personalized Antiretroviral Therapies Against HIV

Journal

Journal Title*:

Lecture Notes in Computer Science

Journal's URL:

http://www.springerlink.com/content/f5121n1715k50631/

Download URL
for the article:

http://www.springerlink.com/content/f5121n1715k50631/fulltext.pdf

Language:

English

Publisher

Publisher's
Name:

Springer

Publisher's URL:

http://www.springer.com

Publisher's
Address:

Berlin, Germany

ISSN:

0302-9743

Vol, No, pp, Date

Volume*:

4075

Number:


Publishing Date:

July 2006

Pages*:

185-194

Number of
VG Pages:


Page Start:


Page End:


Sequence Number:


DOI:


Note, Abstract, ©

Note:


(LaTeX) Abstract:

Despite the availability of antiretroviral combination therapies, success in drug treatment of HIV-infected patients is limited. One reason for therapy failure is the development of drug-resistant genetic variants. In principle, the viral genomic sequence provides resistance information and could thus guide the selection of an optimal drug combination. In practice however, the benefit of this procedure is impaired by (1) the difficulty in inferring the clinically relevant information from the genotype of the virus and (2) the restricted availability of this information. We have developed a secure platform for collaborative research aimed at optimizing anti-HIV therapies, called Arevir. A relational database schema was designed and implemented together with a web-based user interface. Our system provides a basis for monitoring patients, decision-support, and computational analyses. Thus, it merges clinical, diagnostic and bioinformatics efforts to exploit genomic and patient therapy data in clinical practice.

URL for the Abstract:

http://www.springerlink.com/content/f5121n1715k50631/

Categories,
Keywords:


HyperLinks / References / URLs:


Copyright Message:


Personal Comments:


Download
Access Level:

Intranet

Correlation

MPG Unit:

Max-Planck-Institut für Informatik



MPG Subunit:

Computational Biology and Applied Algorithmics

Appearance:

MPII WWW Server, MPII FTP Server, MPG publications list, university publications list, working group publication list, Fachbeirat, VG Wort


BibTeX Entry:

@ARTICLE{Roomp2006,
AUTHOR = {Roomp, Kirsten and Beerenwinkel, Niko and Sing, Tobias and Sch{\"u}lter, Eugen and B{\"u}ch, Joachim and Sierra-Aragon, Saleta and D{\"a}umer, Martin and Hoffmann, Daniel and Kaiser, Rolf and Lengauer, Thomas and Selbig, Joachim},
TITLE = {Arevir: A Secure Platform for Designing Personalized Antiretroviral Therapies Against {HIV}},
JOURNAL = {Lecture Notes in Computer Science},
PUBLISHER = {Springer},
YEAR = {2006},
VOLUME = {4075},
PAGES = {185--194},
ADDRESS = {Berlin, Germany},
MONTH = {July},
ISBN = {0302-9743},
}


Entry last modified by Christine Kiesel, 01/27/2015
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Editor(s)
[Library]
Created
03/13/2007 06:32:24 PM
Revisions
3.
2.
1.
0.
Editor(s)
Christine Kiesel
Christine Kiesel
Joachim Büch
Joachim Büch
Edit Dates
02.04.2007 09:27:49
30.03.2007 16:07:45
13.03.2007 18:33:52
13.03.2007 18:32:24