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#YearedocLckAuthor(s) [non member]Editor(s) [non member]TitleType
309
Hide details for Veröffentlichungen der MitarbeiterVeröffentlichungen der Mitarbeiter
2011[Alcaro, Stefano]
[Alteri, Claudia]
[Artese, Anna]
[Ceccherini-Silberstein, Francesca]
[Costa, Giosuè]
[Ortuso, Francesco]
[Forbici, Federica]
[Santoro, Maria Mercedes]
[Parrotta, Lucia]
[Flandre, Philippe]
[Descamps, Diane]
[Calvez, Vincent]
[Marcelin, Anne-Genevieve]
[Perno, Carlo Federico]
Sing, Tobias
[Svicher, Valentina]
Docking Analysis and Resistance Evaluation of Clinically Relevant Mutations Associated with the HIV-1 Nonnucleoside Reverse Transcriptase Inhibitors Nevirapine, Efavirenz and Etravirine
In: ChemMedChem [6], 2203-2213
Journal Article
2011[Aranda, Bruno]
Blankenburg, Hagen
[Kerrien, Samuel]
[Brinkman, Fiona S.]
[Ceol, Arnaud]
[Chautard, Emilie]
[Dana, Jose M.]
[De Las Rivas, Javier]
[Dumousseau, Marine]
[Galeota, Eugenia]
[Gaulton, Anna]
[Goll, Johannes]
[Hancock, Robert E. W.]
[Isserlin, Ruth]
[Jimenez, Rafael C.]
[Kerssemakers, Jules]
[Khadake, Jyoti]
[Lynn, David J.]
[Michaut, Magali]
[O'Kelly, Gavin]
[Ono, Keiichiro]
[Orchard, Sandra]
[Prieto, Carlos]
[Razick, Sabry]
[Rigina, Olga]
[Salwinski, Lukasz]
[Simonovic, Milan]
[Velankar, Sameer]
[Winter, Andrew]
[Wu, Guanming]
[Bader, Gary D.]
[Cesareni, Gianni]
[Donaldson, Ian M.]
[Eisenberg, David]
[Kleywegt, Gerard J.]
[Overington, John]
[Ricard-Blum, Sylvie]
[Tyers, Mike]
Albrecht, Mario
[Hermjakob, Henning]
PSICQUIC and PSISCORE: accessing and scoring molecular interactions
In: Nature Methods [8], 528-529
Journal Article
2011[Bleif, Sabrina]
[Hannemann, Frank]
[Lisurek, Michael]
[von Kries, Jens Peter]
[Zapp, Josef]
Dietzen, Matthias
[Antes, Iris]
[Bernhardt, Rita]
Identification of CYP106A2 as a Regioselective Allylic Bacterial Diterpene Hydroxylase
In: ChemBioChem [12], 576-582
Journal Article
2011Bock, Christoph
[Kiskinis, Evangelos]
[Verstappen, Griet]
[Gu, Hongcang]
[Boulting, Gabriella]
[Smith, Zachary D.]
[Ziller, Michael]
[Croft, Gist F.]
[Amoroso, MacKenzie W.]
[Oakley, Derek H.]
[Gnirke, Andreas]
[Eggan, Kevin]
[Meissner, Alexander]
Reference Maps of Human ES and iPS Cell Variation Enable High-Throughput Characterization of Pluripotent Cell Lines
In: Cell [144], 439-452
Journal Article
2011[Cerdeira, Louise Teixeira]
[Carneir, Aadriana Ribeiro]
[Ramos, Rommel Thiago Juca]
[de Almeida, Sintia Silva]
[D'Afonseca, Vivian]
[Schneider, Maria Paula Cruz]
Baumbach, Jan
[Tauch, Andreas]
[McCulloch, John Anthony]
[Azevedo, Vasco Ariston Carvalho]
[Silva, Aartur]
Rapid hybrid de novo assembly of a microbial genome using only short reads: Corynebacterium pseudotuberculosis I19 as a case study
In: Journal of Microbiological Methods [86], 218-223
Journal Article
2011Döring, MatthiasWeb Implementation of the HBV Dual Infection Model
Universität des Saarlandes
Thesis - Bachelor thesis
2011Doncheva, Nadezhda T.
[Klein, Karsten]
Domingues, Francisco S.
Albrecht, Mario
Analyzing and visualizing residue networks of protein structures
In: Trends in Biochemical Sciences [36], 179-182
Journal Article
2011Emig, Dorothea
Albrecht, Mario
Tissue-specific proteins and functional implications
In: Journal of Proteome Research [10], 1893-1903
Journal Article
2011Emig, Dorothea
Kacprowski, Tim
Albrecht, Mario
Measuring and analyzing tissue specificity of human genes and protein complexes
In: EURASIP Journal on Bioinformatics and Systems Biology [2011], 5,1-5,6
Journal Article
2011Feuerbach, Lars
[Lyngso, Rune B.]
Lengauer, Thomas
[Hein, Jotun]
Reconstructing the ancestral germline methylation state of young repeats
In: Molecular Biology and Evolution [28], 1777-1784
Journal Article
2011[Gu, Hongcang]
[Smith, Zachary D.]
Bock, Christoph
[Boyle, Patrick]
[Gnirke, Andreas]
[Meissner, Alexander]
Preparation of reduced representation bisulfite sequencing libraries for genome-scale DNA methylation profiling
In: Nature Protocols [6], 468-481
Journal Article
2011[Heger, Eva]
Thielen, Alexander
[Gilles, Ramona]
[Obermeier, Martin]
Lengauer, Thomas
[Kaiser, Rolf]
[Trapp, Susanna]
APOBEC3G/F as one possible driving force for co-receptor switch of the human immunodeficiency virus-1
In: Medical Microbiology and Immunology [201], 7-16
Journal Article
2011[Hofmann, Wolf Peter]
[Chung, Tje Lin]
[Osbahr, Carola]
[Susser, Simone]
[Karey, Ursel]
[Mihm, Ulrike]
Welsch, Christoph
[Lötsch, Jörn]
[Sarrazin, Christoph]
[Zeuzem, Stefan]
[Herrmann, Eva]
Impact of ribavirin on HCV replicon RNA decline during treatment with interferon-α and the protease inhibitors boceprevir or telaprevir
In: Antiviral Therapy [16], 695-704
Journal Article
2011[Knoepfel, Stefanie]
[Di Giallonardoc, Francesca]
[Däumer, Martin]
Thielen, Alexander
[Metzner, Karin J]
In-depth analysis of G-to-A hypermutation rate in HIV-1 env DNA induced by endogenous APOBEC3 proteins using massively parallel sequencing
In: Journal of Virological Methods [71], 329-338
Journal Article
2011[Krol, Elizaveta]
[Blom, Jochen]
[Winnebald, Jörn]
[Berhörster, Alexander]
[Barnett, Melanie J.]
[Goesmann, Alexander]
Baumbach, Jan
[Becker, Anke]
RhizoRegNet - A database of rhizobial transcription factors and regulatory networks.
In: Journal of Biotechnology [155], 127-134
Journal Article
2011[Kumar, Vinod]
Sun, Peng
[Vamathevan, Jessica]
[Li, Yong]
[Ingraham, Karen]
[Palmer, Leslie]
[Huang, Jianzhong]
[Brown, James R.]
Comparative Genomics of Klebsiella pneumoniae Strains with Different Antibiotic Resistance Profiles
In: Antimicrobial Agents and Chemotherapy [55], 4267-4276
Journal Article
2011Lawyer, Glenn
Altmann, André
Thielen, Alex
[Zazzi, Maurizio]
[Sönnerborg, Anders]
Lengauer, Thomas
HIV-1 mutational pathways under multidrug therapy
In: AIDS Research and Therapy [8], 1-13
Journal Article
2011Lengauer, ThomasComputermodelle in der Wissenschaft - zwischen Analyse, Vorhersage und SuggestionBook
2011[Lutsik, Pavlo]
Feuerbach, Lars
[Arand, Julia]
Lengauer, Thomas
[Walter, Jörn]
Bock, Christoph
BiQ Analyzer HT: locus-specific analysis of DNA methylation by high-throughput bisulfite sequencing
In: Nucleic Acids Research [39], W551-W556
Journal Article
2011[Morris, John H.]
[Apeltsin, Leonard]
[Newman, Aaron M.]
Baumbach, Jan
[Wittkop, Tobias]
[Su, Gang]
[Bader, Gary D.]
[Ferrin, Thomas E.]
clusterMaker: A Multi-algorithm Clustering Plugin for Cytoscape
In: BMC Bioinformatics [12], 436,1-436,14
Journal Article
2011Nebot, Victoria
Ye, Min
Albrecht, Mario
Eom, Jae-Hong
Weikum, Gerhard
DIDO: a disease-determinants ontology from web sources
In: Proceedings of the 20th International Conference on World Wide Web (WWW 2011), 237-240
Proceedings Article
2011Stop sign IconPironti, Alejandro
Altmann, André
Büch, Joachim
Lengauer, Thomas
Stop sign IconA Computational Method for Predicting First-Line Antiretroviral Therapy Success
In: Abstract Book. 9th Workshop on HIV & Hepatitis Treatment Strategies & Antiviral Drug Resistance, 94
Poster
2011[Ramos, Rommel T.J.]
[Carneiro, Adriana R.]
Baumbach, Jan
[Azevedo, Vasco]
[Schneider, Maria P.C.]
[Silva, Artur]
Analysis of quality raw data of second generation sequencers with Quality Assessment Software
In: BMC Research Notes [4], 130,1-130,6
Journal Article
2011[Reiss, Simon]
[Rebhan, Ilka]
[Backes, Perdita]
[Romero-Brey, Ines]
[Erfle, Holger]
[Matula, Petr]
[Kaderali, Lars]
[Poenisch, Marion]
Blankenburg, Hagen
[Hiet, Marie-Sophie]
[Longerich, Thomas]
Diehl, Sarah
Ramírez, Fidel
[Balla, Tamas]
[Rohr, Karl]
[Kaul, Artur]
[Bühler, Sandra]
[Pepperkok, Rainer]
Lengauer, Thomas
Albrecht, Mario
[Eils, Roland]
[Schirmacher, Peter]
[Lohmann, Volker]
[Bartenschlager, Ralf]
Recruitment and activation of a lipid kinase by hepatitis C virus NS5A is essential for integrity of the membranous replication compartment
In: Cell Host & Microbe [9], 32-45
Journal Article
2011Reuter, KerstinEstimating and Using the Uncertainty in the Phenotypic Resistance Assay of the Hepatitis B Virus to Improve IC-50 Prediction from Genotype
Universität des Saarlandes
Thesis - Bachelor thesis
2011[Reuter, Stefan]
[Oette, Mark]
[Wilhelm, Frank Clemens]
Beggel, Bastian
[Kaiser, Rolf]
[Balduin, Melanie]
[Schweitzer, Finja]
[Verheyen, Jens]
[Adams, Ortwin]
Lengauer, Thomas
[Faetkenheuer, Gerd]
[Pfister, Herbert]
[Haeussinger, Dieter]
Attachment IconErratum to: Prevalence and characteristics of hepatitis B and C virus infections in treatment-naïve HIV-infected patients.
In: Medical Microbiology and Immunology [200], 51-51
Journal Article
2011[Reuter, Stefan]
[Oette, Mark]
[Wilhelm, Frank Clemens]
Beggel, Bastian
[Kaiser, Rolf]
[Balduin, Melanie]
[Schweitzer, Finja]
[Verheyen, Jens]
[Adams, Ortwin]
Lengauer, Thomas
[Faetkenheuer, Gerd]
[Pfister, Herbert]
[Haeussinger, Dieter]
Prevalence and characteristics of hepatitis B and C virus infections in treatment-naïve HIV-infected patients
In: Medical Microbiology and Immunology [200], 39-49
Journal Article
2011Roomp, Kirsten
Domingues, Francisco S.
Predicting interactions between T cell receptors and MHC-peptide complexes
In: Molecular Immunology [48], 553-562
Journal Article
2011[Santos, Anderson R]
[Santos, Marcos A]
Baumbach, Jan
[McCulloch, John A]
[Oliveira, Guilherme C]
[Silva, Artur]
[Miyoshi, Anderson]
[Azevedo, Vasco]
A singular value decomposition approach for improved taxonomy classification of biological sequences
In: BMC Genomics [12], S11,1-S11,15
Journal Article
2011[Schülter, Eugen]
[Oette, Mark]
[Balduin, Melanie]
[Reuter, Stefan]
[Rockstroh, Jürgen]
[Fätkenheuer, Gerd]
[Esser, Stefan]
Lengauer, Thomas
[Agacfidan, Ali]
[Pfister, Herbert]
[Kaiser, Rolf]
[Akgul, Baki]
HIV prevalence and route of transmission in Turkish immigrants
living in North-Rhine Westphalia, Germany
In: Medical Microbiology and Immunology [200], 219-223
Journal Article
2011[Seclen, Eduardo]
[Soriano, Vincente]
[González, Maria M]
[Gómez, Sagrario]
Thielen, Alexander
[Poveda, Eva]
High Concordance between the Position-Specific Scoring Matrix and Geno2pheno Algorithms for Genotypic Interpretation of HIV-1 Tropism: V3 Length as the Major Cause of Disagreement
In: Journal of Clinical Microbiology [49], 3380-3382
Journal Article
2011[Shimakami, Tetsuro]
Welsch, Christoph
[Yamane, Daisuke]
[McGivern, David R.]
[Yi, MinKyung]
[Zeuzem, Stefan]
[Lemon, Stanley M.]
Protease Inhibitor-Resistant Hepatitis C Virus Mutants With Reduced Fitness From Impaired Production of Infectious Virus
In: Gastroenterology [140], 667-675
Journal Article
2011[Svicher, Valentina]
[Cento, Valeria]
[Salpini, Romina]
[Mercurio, Fabio]
[Fraune, Maria]
Beggel, Bastian
[Han, Yue]
[Gori, Caterina]
[Wittkop, Linda]
[Bertoli, Ada]
[Micheli, Valeria]
[Gubertini, Guido]
[Longo, Roberta]
[Romano, Sara]
[Visca, Michela]
[Gallinaro, Valentina]
[Marino, Nicoletta]
[Mazzotta, Francesco]
[De Sanctis, Giuseppe Maria]
[Fleury, Hervè]
[Trimoulet, Pascale]
[Angelico, Mario]
[Cappiello, Giuseppina]
[Zhang, Xin Xin]
[Verheyen, Jens]
[Ceccherini-Silberstein, Francesca]
[Perno, Carlo Federico]
Role of hepatitis B virus genetic barrier in drug-resistance and immune-escape development
In: Digestive and Liver Disease [43], 975-983
Journal Article
2011[Swenson, Luke C]
[Mo, Theresa]
[Dong, Winnie WY]
[Zhong, Xiaoyin]
[Woods, Conan K]
Thielen, Alexander
[Jensen, Mark A]
[Knapp, David JHF]
[Chapman, Douglass]
[Lewis, Marilyn]
[James, Ian]
[Heera, Jayvant]
[Valdez, Hernan]
[Harrigan, P Richard]
Deep V3 sequencing for HIV type 1 tropism in treatment-naive patients: a reanalysis of the MERIT trial of maraviroc.
In: Clinical Infectious Diseases [53], 732-742
Journal Article
2011[Swenson, Luke C.]
[Mo, Theresa]
[Dong, Winnie W. Y.]
[Zhong, Xiaoyin]
[Woods, Conan K.]
[Jensen, Mark A.]
Thielen, Alexander
[Chapman, Douglass]
[Lewis, Marilyn]
[James, Ian]
[Heera, Jayvant]
[Valdez, Hernan]
[Harrigan, P. Richard]
Deep Sequencing to Infer HIV-1 Co-Receptor Usage: Application to Three Clinical Trials of Maraviroc in Treatment-Experienced Patients
In: The Journal of Infectious Diseases [203], 237-245
Journal Article
2011Thielen, Alexander
Lengauer, Thomas
[Swenson, Luke C]
[Dong, Winnie W.Y.]
[McGovern, Rachel A]
[Lewis, Marilyn]
[James, Ian]
[Heera, Jayvant]
[Valdez, Hernan]
[Harrigan, P Richard]
Mutations in gp41 are correlated with coreceptor tropism but do not improve prediction methods substantially
In: Antiviral Therapy [16], 319-328
Journal Article
2011Tolosi, Laura
Lengauer, Thomas
Classification with correlated features: unreliability of feature ranking and solutions
In: Bioinformatics [27], 1986-1994
Journal Article
2011[Welker, M.-W.]
Welsch, Christoph
[Ochs, D.]
[Hofmann, W. P.]
[Herrmann, E.]
[Piiper, A.]
[Hartmann, R. W.]
[Zeuzem, S.]
[Sarrazin, C.]
[Kronenberger, Bernd]
Comparison of Envelope 2 CD81 binding regions in PBMC-derived versus serum-derived hepatitis C virus isolates: higher conservation of CD81 region 2 in PBMC isolates
In: Journal of Viral Hepatitis [18], 181-192
Journal Article
2011[Wittkop, Tobias]
Emig, Dorothea
[Truss, Anke]
Albrecht, Mario
[Böcker, Sebastian]
Baumbach, Jan
Comprehensive cluster analysis with Transitivity Clustering
In: Nature Protocols [6], 285-295
Journal Article
2011[Wittkop, Tobias]
[Rahmann, Sven]
Roettger, Richard
[Boecker, Sebastian]
Baumbach, Jan
Extension and robustness of Transitivity Clustering for protein-protein interaction network analysis
In: Internet Mathematics [7], 255-273
Journal Article
2011[Xi, Yuanxin]
Bock, Christoph
Müller, Fabian
[Sun, Deqiang]
[Meissner, Alexander]
[Li, Wei]
RRBSMAP: A Fast, Accurate and User-friendly Alignment Tool for Reduced Representation Bisulfite Sequencing
In: Bioinformatics [28], 430-432
Journal Article
2011[Yamanishi, Yoshihiro]
[Pauwels, Edouard]
Saigo, Hiroto
[Stovent, Veronique]
Extracting Sets of Chemical Substructures and Protein Domains Governing Drug-Target Interactions
In: Journal of Chemical Information and Modeling [51], 1183-1194
Journal Article
2011[Zacharek, Sima J.]
[Fillmore, Christine M.]
[Lau, Allison N.]
[Gludish, David W.]
[Chou, alan]
[Ho, Joshua W. K.]
[Zamponi, Raffaella]
[Gazit, Roi]
Bock, Christoph
[Jäger, Natalie]
[Smith, Zachary D.]
[Kim, Tae-min]
[Saunders, Arven H.]
[Wong, Janice]
[Lee, Joo-Hyeon]
[Roach, Rebecca R.]
[Rossi, Derrick J.]
[Meissner, Alex]
[Gimelbrant, Alexander A.]
[Park, Peter J.]
[Kim, Carla F.]
Lung stem cell self-renewal relies on BMI1-dependent control of expression at imprinted loci
In: Cell Stem Cell [9], 272-280
Journal Article
2011[Zazzi, M.]
[Kaiser, R.]
[Sönnerborg, A.]
[Struck, D]
Altmann, Andre
[Prosperi, M.]
[Rosen-Zvi, M.]
[Petroczi, A.]
[Peres, Y.]
[Schülter, E.]
[Boucher, C.A.]
[Brun-Vezinet, F.]
[Harrigan, R.]
[Morris, L.]
[Obermeier, M.]
[Perno, C.-F.]
[Phanuphak, P.]
[Pillay, D]
[Shafer, R.W.]
[Vandamme, A.-M.]
[Van Laethem, K.]
[Wensing, A.]
Lengauer, Thomas
[Incardona, F.]
Prediction of Response to Antiretroviral Therapy by Human Experts and by the EuResist Data-Driven Expert System (the EVE study)
In: HIV Medicine [12], 211-218
Journal Article
2010Albrecht, MarioColor blindness
In: Nature Methods [7], 775
Journal Article
2010Albrecht, Mario
[Kerren, Andreas]
[Klein, Karsten]
[Kohlbacher, Oliver]
[Mutzel, Petra]
[Paul, Wolfgang]
[Schreiber, Falk]
[Wybrow, Michael]
[Eppstein, David]
[Gansner, Emden R.]
On open problems in biological network visualization
In: Graph Drawing : 17th International Symposium, GD 2009, 256-267
Proceedings Article
2010Stop sign IconAltmann, Andre
Pironti, Alejandro
Perner, Juliane
Büch, Joachim
Lengauer, Thomas
[Schapiro, Jonathan]
[Boucher, Charles]
Stop sign IconDetermination of clinically relevant cutoffs for HIV-1 phenotypic resistance estimates through a combined analysis of clinical trial and cohort data
In: Abstract Book. 8th European Drug Resistance Workshop, 46
Poster
2010Altmann, André
Tolosi, Laura
Sander, Oliver
Lengauer, Thomas
Permutation importance: an unbiased feature importance measure
In: Bioinformatics [26], 1340-1347
Journal Article
2010Baumbach, JanOn the power and limits of evolutionary conservation - unraveling bacterial gene regulatory networks
In: Nucleic Acids Research [38], 7877-7884
Journal Article
2010Bock, Christoph
[Tomazou, Eleni M.]
[Brinkman, Arie B.]
Müller, Fabian
[Simmer, Femke]
[Gu, Hongcang]
[Jäger, Natalie]
[Gnirke, Andreas]
[Stunnenberg, Hendrik G.]
[Meissner, Alexander]
Attachment IconQuantitative comparison of genome-wide DNA methylation mapping technologies
In: Nature Biotechnology [28], 1106-1114
Journal Article
2010Bock, Christoph
[Von Kuster, Greg]
Halachev, Konstantin
[Taylor, James]
[Nekrutenko, Anton]
Lengauer, Thomas
[Barnes, Michael R.]
[Breen, Gerome]
Web-based analysis of (epi-) genome data using EpiGRAPH and Galaxy.
In: Genetic Variation : Methods and Protocols, 275-296
In: Methods of Molecular Biology [628], 275-296
Part of a Book
2010Bogojeska, Jasmina
[Bickel, Steffen]
Altmann, André
Lengauer, Thomas
Attachment IconDealing with sparse data in predicting outcomes of HIV combination therapies
In: Bioinformatics [26], 2085-2092
Journal Article
2010Bozek, Katarzyna
[Rosahl, A. L.]
[Gaub, S.]
[Lorenzen, S.]
[Herzel, H.]
Circadian transcription in liver
In: Biosystems [102], 61-69
Journal Article
2010[Brunner, Susanne]
[Hurni, Severine]
[Streckeisen, Philipp]
Mayr, Gabriele
Albrecht, Mario
[Yahiaoui, Nabila]
[Keller, Beat]
Intragenic allele pyramiding combines different specificities of wheat Pm3 resistance alleles
In: The Plant Journal [64], 433-445
Journal Article
2010[Codoñer, Francisco M]
[Pou, Christian]
Thielen, Alexander
[García, Federico]
[Delgado, Rafael]
[Dalmau, David]
[Santos, José Ramon]
[Buzón, Maria José]
[Martínez-Picado, Javier Alvarez-Tejado, Miguel]
[Clotet, Bonaventura]
[Ruiz, Lidia]
[Paredes, Roger]
Dynamic escape of pre-existing raltegravir-resistant HIV-1 from raltegravir selection pressure
In: Antiviral Research [88], 281-286
Journal Article
2010[Däumer, Martin]
[Awerkiew, Sabine]
[Sierra Aragon, Saleto]
[Kartashev, Vladimir]
[Poplavskaja, Tatjana]
[Klein, Rolf]
[Sichtig, Nadine]
[Thielen, Bernhard]
Lengauer, Thomas
Roomp, Kirsten
[Pfister, Herbert]
[Kaiser, Rolf]
Short Communication: Selection of Thymidine Analogue Resitance Mutational Patterns in Children from a Common HIV Type 1 Subtype G Source
In: AIDS Research and Human Retroviruses [26], 275-278
Journal Article
2010Dörr, BarbaraUsing copy number variation fpr predicting susceptibility to glioblastoma
Universität des Saarlandes
Thesis - Bachelor thesis
2010[Ellinghaus, Eva]
[Ellinghaus, David]
[Stuart, Philip E.]
[Nair, Rajan P.]
[Debrus, Sophie]
[Raelson, John V.]
[Belouchi, Majid]
[Fournier, Hélène]
[Reinhard, Claudia]
[Ding, Jun]
[Li, Yun]
[Tejasvi, Trilokraj]
[Gudjonsson, Johann]
[Stoll, Stefan W.]
[Voorhees, John J.]
[Lambert, Sylviane]
[Weidinger, Stephan]
[Eberlein, Bernadette]
[Kunz, Manfred]
[Rahman, Proton]
[Gladman, Dafna D.]
[Gieger, Christian]
[Wichmann, H. Erich]
[Karlsen, Tom H.]
Mayr, Gabriele
Albrecht, Mario
[Kabelitz, Dieter]
[Mrowietz, Ulrich]
[Abecasis, Gonçalo R.]
[Elder, James T.]
[Schreiber, Stefan]
[Weichenthal, Michael]
[Franke, Andre]
Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2
In: Nature Genetics [42], 991-995
Journal Article
2010Emig, Dorothea
Kacprowski, Tim
Albrecht, Mario
[Nykter, Matti]
[Ruusuvuori, Pekka]
[Carlberg, Carsten]
[Yli-Harja, Olli]
Measuring and analyzing tissue specificity of human genes and protein complexes
In: Seventh International Workshop on Computational Systems
Biology, WCSB 2010, 27-30
Proceedings Article
2010Emig, Dorothea
[Salomonis, Nathan]
[Baumbach, Jan]
Lengauer, Thomas
[Conklin, Bruce R.]
Albrecht, Mario
AltAnalyze and DomainGraph: analyzing and visualizing exon expression data
In: Nucleic Acids Research [38], W755-W762
Journal Article
2010Stop sign IconFeuerbach, Lars
Lengauer, Thomas
Stop sign IconAncestral germline methylation reconstruction of young repeats
In: Transcription, chromatin structure and DNA repair in development and differentiation, 81
Poster
2010Stop sign IconFeuerbach, Lars
Lyngsoe, Rune
Lengauer, Thomas
[Hein, Jotun]
Stop sign IconComparative Epigenomiocs - Towards Ancestral Germline Methylome Reconstruction
In: Abstracts of papers presented at the 2010 meeting on The Biology of genomes, 87
Poster
2010[Franke, Andre]
[Balschun, Tobias]
[Sina, Christian]
[Ellinghaus, David]
[Häsler, Robert]
Mayr, Gabriele
Albrecht, Mario
[Wittig, Michael]
[Buchert, Eva]
[Nikolaus, Susanna]
[Gieger, Christian]
[Wichmann, H. Erich]
[Sventoraityte, Jurgita]
[Kupcinskas, Limas]
[Onnie, Clive M.]
[Gazouli, Maria]
[Anagnou, Nicholas P.]
[Strachan, David]
[McArdle, Wendy L.]
[Mathew, Christopher G.]
[Rutgeerts, Paul]
[Vermeire, Séverine]
[Vatn, Morten H.]
[Krawczak, Michael]
[Rosenstiel, Philip]
[Karlsen, Tom H.]
[Schreiber, Stefan]
Genome-wide association study for ulcerative colitis identifies risk loci at 7q22 and 22q13 (IL17REL)
In: Nature Genetics [42], 292-294
Journal Article
2010Gatzmann, FannyGOdot Sequence - function prediction from protein sequence
Universität des Saarlandes
Thesis - Bachelor thesis
2010[Gu, Hongcang]
Bock, Christoph
[Mikkelsen, Tarjei S.]
[Jäger, Natalie]
[Smith, Zachary D.]
[Tomazou, Eleni]
[Gnirke, Andreas]
[Lander, Eric S.]
[Meissner, Alexander]
Attachment IconGenome-scale DNA methylation mapping of clinical samples at single-nucleotide resolution
In: Nature Methods [7], 133-136
Journal Article
2010[Harris, R. Alan]
[Wang, Ting]
[Coarfa, Cristian]
[Nagarajan, Raman P.]
[Hong, Chibo]
[Downey, Sara L.]
[Johnson, Brett E.]
[Fouse, Shaun D.]
[Delaney, Allen]
[Zhao, Yongjun]
[Olshen, Adam]
[Ballinger, Tracy]
[Zhou, Xin]
[Forsberg, Kevin J.]
[Gu, Junchen]
[Echipare, Lorigail]
[O'Geen, Heriette]
[Lister, Ryan]
[Pelizzola, Mattia]
[Xi, Yuanxin]
[Epstein, Charles B.]
[Bernstein, Bradley E.]
[Hawkins, R. David]
[Ren, Bing]
[Chung, Wen-Yu]
[Gu, Hongcang]
Bock, Christoph
[Gnirke, Andreas]
[Zhang, Michael Q.]
[Haussler, David]
[Ecker, Joseph R.]
[Li, Wei]
[Farnham, Peggy J.]
[Waterland, Robert a.]
[Meissner, Alexander]
[Marra, Marco A.]
[Hirst, Martin]
[Milosavljevic, Aleksandar]
[Costello, Joseph F.]
Comparison of sequencing-based methods to profile DNA methylation and identification of monoallelic epigenetic modifications
In: Nature Biotechnology [28], 1097-1105
Journal Article
2010Kacprowski, TimAnalysis of protein complexes and tissue-spedific expression
Universität des Saarlandes
Thesis - Bachelor thesis
2010König, EvaEnv-wide analysis of coreceptor determining sites and subtype-specific differences in HIV-1
Universität des Saarlandes
Thesis - Bachelor thesis
2010[Lange, Christian Markus]
Roomp, Kirsten
[Dragan, Anette]
[Nattermann, Jacob]
[Michalk, Monika]
[Spengler, Ulrich]
[Weich, Viola]
Lengauer, Thomas
[Zeuzem, Stefan]
[Berg, Thoma]
[Sarrazin, Christoph]
HLA class I allele associations with HCV genetic variants in patients with chronic HCV genotypes 1a or 1b infection
In: Journal of Hepatology [53], 1022-1028
Journal Article
2010Lengauer, Thomas
Altmann, André
Thielen, Alexander
[Kaiser, Rolf]
Chasing the AIDS Virus
In: Communications of the ACM [53], 66-74
Journal Article
2010[McGovern, Rachel A]
Thielen, Alexander
[Mo, Theresa]
[Dong, Winnie]
[Woods, Conan K]
[Chapman, Douglass]
[Lewis, Marilyn]
[James, Ian]
[Heera, Jayvant]
[Valdez, Hernan]
[Harrigan, P Richard]
Population-based V3 genotypic tropism assay: a retrospective analysis using screening samples from the A4001029 and MOTIVATE studies
In: AIDS [24], 2517-2525
Journal Article
2010[Mihm, Ulrike]
[Hofmann, W.P.]
Welsch, Christoph
[Polta, A.]
Lengauer, Thomas
[Zeuzem, Stefan]
[Sarrazin, Christoph]
[Herrmann, E.]
Effect of ribavirin on the frequency of RNAse L cleavage sites within the hepatitis C viral genome
In: Journal of Viral Hepatitis [17], 217-221
Journal Article
2010Ramírez, Fidel
Albrecht, Mario
Finding scaffold proteins in interactomes
In: Trends in Cell Biology [20], 2-4
Journal Article
2010Ramirez, Fidel[Gomez Merino, Fernando Carlos]
[Silva Rojas, Hilda Victoria]
[Pérez Rodríguez, Paulino]
Tutorial Cytoscape
In: Bioinformática: Aplicaciones a la genómica y proteómica, 73-98
Part of a Book
2010[Rhee, Soo-Yon]
[Margeridon-Thermet, Severin]
[Nguyen, Mindie]
[Liu, Tommy]
[Kagan, Ron]
Beggel, Bastian
[Verheyen, Jens]
[Kaiser, Rolf]
[Shafer, Robert]
Attachment IconHepatitis B virus reverse transcriptase sequence variant database for sequence analysis and mutation discovery
In: Antiviral Research [88], 269-275
Journal Article
2010Schlicker, Andreas
Albrecht, Mario
FunSimMat update: new features for exploring functional similarity
In: Nucleic Acids Research [38], D244-D248
Journal Article
2010Schlicker, Andreas
Lengauer, Thomas
Albrecht, Mario
Improving disease gene prioritization using the semantic similarity of Gene Ontology terms
In: Bioinformatics [26], i561-i567
Journal Article
2010Speicher, Nora K.Network analysis of viral host factors
Universität des Saarlandes
Thesis - Bachelor thesis
2010[Swenson, Luke C.]
[Boehme‌, Richard]
Thielen, Alexander
[McGovern‌, Rachel A.]
[Harrigan, P. Richard]
Genotypic determination of HIV-1 tropism in the clinical setting
In: HIV Therapy [4], 293-303
Journal Article
2010[Swenson, Luke C.]
[Moores, Andrew]
[Low, Andrew J.]
Thielen, Alexander
[Dong, Winnie]
[Woods, Conan]
[Jensen, Mark A.]
[Wynhoven, Brian]
[Chan, Dennison]
[Glascock, Christopher]
[Harrigan, P. Richard]
Improved detection of CXCR4-using HIV by V3 genotyping: application of population-based and "deep" sequencing to plasma RNA and proviral DNA
In: Journal of Acquired Immune Deficiency Syndromes [54], 506-510
Journal Article
2010Stop sign IconThielen, Alexander
Lengauer, Thomas
[Harrigan, P Richard]
[Swenson, Luke]
[Dong, Winnie WY]
[McGovern, Rachel A]
[Lewis, Marilyn]
[James, Ian]
[Heera, Jayvant]
[Valdez, Hernan]
Stop sign IconMutations within GP41 are correlated with coreceptor tropism but do not substantially improve coreceptor usage prediction
In: Reviews in Antiviral Therapy & Infectious Diseases, 47-47
Poster
2010Thielen, Alexander
[Sichtig, Nadine]
[Kaiser, Rolf]
[Lam, Jeffrey]
[Harrigan, P. Richard]
Lengauer, Thomas
Improved prediction of HIV-1 coreceptor usage with sequence information from the second hypervariable loop of gp120
In: Journal of Infectious Diseases [202], 1435-1443
Journal Article
2010[Welker, Martin-Walter]
[Welsch, Christoph]
[Meyer, Aline]
Antes, Iris
Albrecht, Mario
[Forestier, Nicole]
[Kronenberger, Bernd]
Lengauer, Thomas
[Piiper, Albrecht]
[Zeuzem, Stefan]
[Sarrazin, Christoph]
Dimerization of the hepatitis C virus nonstructural protein 4B depends on the integrity of an aminoterminal basic leucine zipper
In: Protein Science [19], 1327-1336
Journal Article
2010[Wittkop, Tobias]
Emig, Dorothea
[Lange, Sita]
[Rahmann, Sven]
Albrecht, Mario
[Morris, John H.]
[Böcker, Sebastian]
[Stoye, Jens]
Baumbach, Jan
Partitioning biological data with transitivity clustering
In: Nature Methods [7], 419-420
Journal Article
2010[Wohlers, Inken]
Domingues, Francisco S.
[Klau, Gunnar W.]
Towards optimal alignment of protein structure distance matrices
In: Bioinformatics [26], 2273-2280
Journal Article
2009Adams, Ben
McHardy, Alice
[Lundegaard, C.]
Lengauer, Thomas
Frishman, Dimitrij
Valencia, Alfonso
Viral Bioinformatics
In: Modern Genome Annotation - The BioSapiens Network, 429-452
Part of a Book
2009[Alcaro, Stefano]
[Artese, Anna]
[Ceccherini-Silberstein, Francesca]
[Ortuso, Francesca]
[Perno, Carlo Federico]
Sing, Tobias
[Svicher, Valentina]
Molecular Dynamics and Free Energy Studies on the Wild-Type and Mutated HIV-1
Protease Complexed with Four Approved Drugs: Mechanism of Binding and
In: Journal of Chemical Information and Modeling [49], 1751-1761
Journal Article
2009Altmann, André
[Däumer, Martin]
[Beerenwinkel, Niko]
[Peres, Yardena]
[Schülter, Eugen]
Büch, Joachim
[Rhee, Soo-Yon]
[Sönnerborg, Anders]
[Fessel, W. Jeffrey]
[Shafer, Robert W.]
[Zazzi, Maurizio]
[Kaiser, Rolf]
Lengauer, Thomas
Predicting the Response to Combination Antiretroviral Therapy: Retrospective Validation of
geno2pheno-THEO on a Large Clinical Database
In: The Journal of Infectious Diseases [199], 999-1006
Journal Article
2009Altmann, André
Sing, Tobias
[Vermeiren, Hans]
[Winters, Bart]
[Van Craenenbroeck, Elke]
[Van der Borght, Koen]
[Rhee, Soo-Yon]
Shafer, Robert W.
[Schülter, Eugen]
[Kaiser, Rolf]
[Peres, Yardena]
[Sönnerborg, Anders]
Fessel, W. Jeffrey
[Incardona, Francesca]
[Zazzi, Maurizio]
[Bacheler, Lee]
[Van Vlijmen, Hermann]
Lengauer, Thomas
Advantages of Predicted Phenotypes and Statistical Learning Models in Inferring Virological Response to Antiretroviral Therapy from HIV Genotype
In: Antiviral Therapy [14], 273-283
Journal Article
2009Blankenburg, Hagen
[Finn, Robert D.]
[Prlić, Andreas]
[Jenkinson, Andrew M.]
Ramírez, Fidel
Emig, Dorothea
Schelhorn, Sven-Eric
Büch, Joachim
Lengauer, Thomas
Albrecht, Mario
DASMI: exchanging, annotating and assessing molecular interaction data
In: Bioinformatics [25], 1321-1328
Journal Article
2009Bock, ChristophAttachment IconEpigenetic biomarker development
In: Epigenomics [1], 99-110
Journal Article
2009Bock, Christoph
Halachev, Konstantin
Büch, Joachim
Lengauer, Thomas
Attachment IconEpiGRAPH: user-friendly software for statistical analysis and prediction of (epi)genomic data
In: Genome Biology [10], R14.1-R14.14
Journal Article
2009Ebert, PeterComputational Analysis of genomic HPV data
Universität des Saarlandes
Thesis - Bachelor thesis
2009Stop sign IconFeuerbach, Lars
Halachev, Konstantin
Lengauer, Thomas
Bock, Christoph
[Meijer, Gerrit]
[Ried, Thomas]
[Giaretti, Walter]
[Hamilton, Peter]
Stop sign IconAn exhaustive methode for CpG island annotation
In: Special Issue: Abstracts of the 3rd MC-GARD Meeting, 146-146
Poster
2009[Frishman, Dmitrij]
Albrecht, Mario
Blankenburg, Hagen
[Bork, Peer]
[Harrington, Eoghan D.]
[Hermjakob, Henning]
[Jensen, Lars J.]
[Juan, David A.]
Lengauer, Thomas
[Pagel, Philipp]
[Schachter, Vincent]
[Valencia, Alfonso]
[Frishman, Dmitrij]
[Valencia, Alfonso]
Protein-protein interactions: analysis and prediction
In: Modern Genome Annotation - The Biosapiens Network, 353-410
Part of a Book
2009Stop sign Icon[Harrigan, P Richard]
[McGovern, Rachel]
[Dong, Winnie]
Thielen, Alexander
[Jensen, Mark]
[Mo, Theresa]
[Chapman, Douglas]
[Lewis, Marilyn]
[James, Ian]
[Valdez, Hernan]
Stop sign IconScreening for HIV tropism using population-based V3 genotypic analysis: a retrospective outcome analysis using stored plasma screening samples from MOTIVATE-1
In: Abstracts presented at the XVIII International HIV Drug Resistance Workshop : Basic Principles & Clinical Implications, A17-A17
Poster
2009Hartmann, Christoph
Antes, Iris
Lengauer, Thomas
Docking and scoring with alternative side-chain conformations
In: Proteins: Structure, Function, and Bioinformatics [74], 712-726
Journal Article
2009[Kono, Ken]
Bozek, Kasia
Domingues, Francisco S.
[Shioda, Tatsuo]
[Nakayama, Emi E.]
Impact of a single amino acid in the variable region 2 of the Old World monkey TRIM5alpha SPRY (B30.2) domain on anti-human immunodeficiency virus type 2 activity
In: Virology [388], 160-168
Journal Article
2009Stop sign Icon[Lawyer, Glenn]
[Ferkingstad, Egil]
[Nesvåg, Rangan]
[Varnäs, Katarina]
[Agartz, Ingrid]
Stop sign IconLocal and covariate-modulated false discovery rates applied in neuroimaging
In: NeuroImage [47], 213-219
Journal Article
2009Stop sign Icon[Lawyer, Glenn]
[Nesvåg, Ragnar]
[Varnäs, Katarina]
[Okugawa, Gaku]
[Agartz, Ingrid]
Stop sign IconGrey and white matter proportional relationships in the cerebellar vermis altered in schizophrenia
In: Cerebellum [8], 52-60
Journal Article
2009Lengauer, Thomas
Altmann, André
Thielen, Alexander
Bioinformatische Unterstützung der Auswahl von HIV Therapien
In: Informatik Spektrum [32], 320-331
Journal Article
2009Lengauer, Thomas
[Kaiser, Rolf]
Computerjagd auf das AIDSVIRUS
In: Spektrum der Wissenschaft [08], 62-67
Journal Article
2009Lengauer, Thomas
[Sierra, S.]
[Kaiser, Rolf]
Resistenzbestimmung
In: MMW Fortschritte in der Medizin [151], 74-75
Journal Article
2009Mangels, MiriamIn Silico Models for the Prediction of Metabolism by Cytochrome P450 Enzymes
Universität des Saarlandes
Thesis - Bachelor thesis
2009[Mihm, Ulrike]
[Ackermann, Oliver]
Welsch, Christoph
[Herrmann, Eva]
[Hofmann, Wolf Peter]
[Grigorian, Natalia]
[Welker, Martin Walter]
Lengauer, Thomas
[Zeuzem, Stefan]
[Sarrazin, Christoph]
Clinical relevance of the 2'-5'-oligoadenylate synthetase/RNase L system for treatment response in chronic hepatitis C
In: Journal of Hepatology [50], 49-58
Journal Article
2009[Moser, Dirk]
[Ekawardhani, Savira]
[Kumsta, Robert]
[Palmason, Haukur]
Bock, Christoph
[Athanassiadou, Zoi]
[Lesch, Klaus-Peter]
[Meyer, Jobst]
Attachment IconFunctional Analysis of a Potassium-Chloride Co-Transporter 3 (SLC12A6) Promoter Polymorphism Leading to an Additional DNA Methylation Site
In: Neuropsychopharmacology [34], 458-467
Journal Article
2009[Prosperi, Mattia C. F.]
Altmann, André
[Rosen-Zvi, Michal]
[Aharoni, Ehud]
[Gabor, Borgulya]
[Fulop, Bazso]
[Sonnerborg, Anders]
[Schulter, Eugen]
[Struck, Daniel]
[Ulivi, Giovanni]
[Vandamme, Anne-Mieke]
[Vercauteren, Jurgen]
[Zazzi, Maurizio]
Investigation of expert rule bases, logistic regression, and non-linear machine learning techniques for predicting response to antiretroviral treatment
In: Antiviral Therapy [14], 433-442
Journal Article
2009Roomp, Kirsten
[Rand, Jacquie]
Intensive blood glucose control is safe and effective in diabetic cats using home monitoring and treatment with glargine
In: Journal of feline medicine and surgery [11], 668-682
Journal Article
2009Schüffler, Peter
[Mikeska, Thomas]
[Waha, Andreas]
Lengauer, Thomas
Bock, Christoph
Attachment IconMethMarker: User-friendly design and optimization of gene-specific DNA methylation assays
In: Genome Biology [10], R105:1-R105:10
Journal Article
2009[Sichtig, Nadine]
[Sierra, Saleta]
[Kaiser, Rolf]
[Däumer, Martin]
[Reuter, Stefan]
[Schülter, Eugen]
Altmann, André
[Fätkenheuer, Gerd]
[Dittmer, Ulf]
[Pfister, Herbert]
[Esser, Stefan]
Evolution of raltegravir resistance during therapy
In: Journal of antimicrobial chemotherapy [64], 25-32
Journal Article
2009[Sos, Martin L.]
[Michel, Kathrin]
[Zander, Thomas]
[Weiss, Jonathan]
[Frommolt, Peter]
[Pfeifer, Martin]
[Li, Danan]
[Ullrich, Roland]
[Koker, Mirjam]
[Fischer, Florian]
[Shimamura, Takeshi]
[Rauh, Daniel]
[Mermel, Craig]
[Fischer, Stefanie]
[Stückrath, Isabel]
[Heynck, Stefanie]
[Beroukhim, Rameen]
[Lin, William]
[Winckler, Wendy]
[Shah, Kinjal]
[LaFramboise, Thomas]
[Moriarty, Whei F.]
Hanna, megan
Tolosi, Laura
[Rahnenführer, Jörg]
[Verhaak, Roel]
[Chiang, Derek]
[Getz, Gad]
[Hellmich, Martin]
[Wolf, Jürgen]
[Girard, Luc]
[Peyton, Michael]
[Weir, Barbara A.]
[Chen, Tzu-Hsiu]
[Greulich, Heidi]
[Barretina, Jordi]
[Shapiro, Geoffrey I.]
[Garraway, Levi A.]
[Gazdar, Adi F.]
[Minna, John D.]
[Meyerson, Matthew]
[Wong, Kwok-Kin]
[Thomas, Roman K.]
Predicting drug susceptibility of non-small cell lung cancers based on genetic lesions
In: Journal of Clinical Investigation [119], 1727-1740
Journal Article
2009[Susser, Simone]
Welsch, Christoph
[Wang, Yalan]
[Zettler, Markus]
Domingues, Francisco S.
[Karey, Ursula]
[Hughes, Eric]
[Ralston, Robert]
[Tong, Xiao]
[Herrmann, Eva]
[Zeuzem, Stefan]
[Sarrazin, Christoph]
Characterization of resistance to the protease inhibitor boceprevir in hepatitis C virus-infected patients.
In: Hepatology [50], 1709-1718
Journal Article
2009Stop sign IconThielen, Alexander
Altmann, André
Bogojeska, Jasmina
[Kaiser, Rolf]
Lengauer, Thomas
Stop sign IconEstimating evolutionary pathways to 7CXCR4 usage from cross-sectional data
In: Abstracts presented at the XVIII International HIV Drug Resistance Workshop : Basic Principles & Clinical Implications, A16-A16
Poster
2009Stop sign IconThielen, Alexander
[Sichtig, Nadine]
[Braun, Patrick]
[Däumer, Martin]
[Walter, Hauke]
[Noah, Christian]
[Wolf, Eva]
[Müller, Harm]
[Stürmer, Martin]
Lengauer, Thomas
[Kaiser, Rolf]
[Obermeier, Martin]
Stop sign IconPerformance of genotypic coreceptor measurement using geno2pheno[coreceptor] in B- and non-B HIV subtypes in a large cohort of therapy-experienced patients in Germany
In: Reviews in Antiviral Therapy, 99-99
Poster
2009[Trignetti, Maria]
Sing, Tobias
[Svicher, Valentina]
[Santoro, Maria Mercedes]
[Forbici, Federica]
[D'Arrigo, Roberta]
[Bellocchi, Maria Concetta]
[Santoro, Mario]
[Marconi, Patrizia]
[Zaccarelli, Mauro]
[Trotta, Maria Paola]
[Bellagamba, Rita]
[Narciso, Pasquale]
[Antinori, Andrea]
Lengauer, Thomas
[Perno, Carlo Federico]
[Ceccherini-Silberstein, Francesca]
Dynamics of NRTI resistance mutations during therapy interruption
In: AIDS Research and Human Retroviruses [25], 57-64
Journal Article
2009Weimann, AaronUsing multidimensional Scaling for visualizing similarities of proteins
Universität des Saarlandes
Thesis - Bachelor thesis
2008Stop sign IconAltmann, Andre
[Rosen-Zvi, Michal]
[Prosperi, Mattia]
[Aharoni, Ehud]
[Neuvirth, Hani]
[Schülter, Eugen]
Büch, Joachim
[Peres, Yardena]
[Incardona, Incardona]
[Sönnerborg, Anders]
[Kaiser, Rolf]
[Zazzi, Maurizio]
Lengauer, Thomas
Stop sign IconThe EuResist approach for predicting response to anti HIV-1 therapy
In: Reviews in Antiviral Therapy, 107
Poster
2008Altmann, Andre
[Rosen-Zvi, Michal]
[Prosperi, Mattia]
[Aharoni, Ehud]
[Neuvirth, Hani]
[Sönnerborg, Anders]
[Schülter, Eugen]
Büch, Joachim
[Struck, Daniel]
[Peres, Yardena]
[Incardona, Francesca]
[Kaiser, Rolf]
[Zazzi, Maurizio]
Lengauer, Thomas
Comparison of Classifier Fusion Methods for Predicting Response to Anti HIV-1 Therapy
In: PLoS ONE [3], e3470
Journal Article
2008Assenov, Yassen
Ramírez, Fidel
Schelhorn, Sven-Eric
Lengauer, Thomas
Albrecht, Mario
Computing topological parameters of biological networks
In: Bioinformatics [24], 282-284
Journal Article
2008Bickel, Steffen
Bogojeska, Jasmina
Lengauer, Thomas
Sheffer, Tobias
[McCallum, Andrew]
[Roweis, Sam]
Attachment IconMulti-Task Learning for HIV Therapy Screening
In: Proceedings, Twenty-Fifth International Conference on Machine Learning, 56-63
Proceedings Article
2008Bock, ChristophIVF: stars may have to consider the risk of stolen parenthood
In: Nature [454], 938
Journal Article
2008Bock, Christoph
Lengauer, Thomas
Attachment IconComputational epigenetics
In: Bioinformatics [24], 1-10
Journal Article
2008Bock, Christoph
[Walter, Jörn]
[Paulsen, Martina]
Lengauer, Thomas
Attachment IconInter-individual variation of DNA methylation and its implications for large-scale epigenome mapping
In: Nucleic Acids Research [36], e55
Journal Article
2008Bogojeska, Jasmina
Alexa, Adrian
Altmann, André
Lengauer, Thomas
[Rahnenführer, Jörg]
Attachment IconRtreemix: an R package for estimating evolutionary pathways and genetic progression scores
In: Bioinformatics [24], 2391-2392
Journal Article
2008Bogojeska, Jasmina
Lengauer, Thomas
[Rahnenführer, Jörg]
Stability analysis of mixtures of mutagenetic trees
In: BMC Bioinformatics [9], 165-181
Journal Article
2008Stop sign IconDäumer, Martin
[Kaiser, Rolf]
[Klein, Rolf]
Lengauer, Thomas
[Thiele, Bernhard]
Thielen, Alexander
Stop sign IconInferring viral tropism from genotype with massively parallel sequencing; qualitative and quantitative analysis
In: Antiviral Therapy, A101
Poster
2008Emig, Dorothea
[Cline, Melissa S.]
[Klein, Karsten]
[Kunert, Anne]
[Mutzel, Petra]
Lengauer, Thomas
Albrecht, Mario
Integrative visual analysis of the effects of alternative splicing on protein domain interaction networks
In: Journal of Integrative Bioinformatics [5], 101-115
Journal Article
2008Emig, Dorothea
[Cline, Melissa S.]
Lengauer, Thomas
Albrecht, Mario
Integrating expression data with domain interaction networks
In: Bioinformatics [24], 2546-2548
Journal Article
2008Emig, Dorothea
[Klein, Karsten]
[Kunert, Anne]
[Mutzel, Petra]
Albrecht, Mario
Visualizing domain interaction networks and the impact of alternative splicing events
In: Proceedings of the 5th International Conference on BioMedical Visualization (MediVis): Information Visualization in Medical and Biomedical Informatics, 36-43
Proceedings Article
2008[Franke, Andre]
[Balschun, Tobias]
[Karlsen, Tom H.]
[Sventoraityte, Jurgita]
[Nikolaus, Susanna]
Mayr, Gabriele
Domingues, Francisco S.
Albrecht, Mario
[Nothnagel, Michael]
[Ellinghaus, David]
[Sina, Christian]
[Onnie, Clive M.]
[Weersma, Rinse K.]
[Stokkers, Pieter C. F.]
[Wijmenga, Cisca]
[Gazouli, Maria]
[Strachan, David]
[McArdle, Wendy L.]
[Vermeire, Séverine]
[Rutgeers, Paul]
[Rosenstiel, Philip]
[Krawczak, Michael]
[Vatn, Morten H.]
[IBSEN study group, the]
[Mathew, Christopher G.]
[Schreiber, Stefan]
Sequence variants in IL10, ARPC2, and multiple other loci contribute to ulcerative colitis
In: Nature Genetics [40], 1319-1323
Journal Article
2008[Hornstein, Max]
[Hoffmann, Michele J.]
Alexa, Adrian
[Yamanaka, Masanori]
[Müller, Mirko]
[Jung, Volker]
[Rahnenführer, Jörg]
[Schulz, Wolfgang A.]
Protein phosphatase and TRAIL receptor genes as new candidate tumor genes on chromosome 8p in prostate cancer
In: Cancer Genomics & Proteomics [5], 123-136
Journal Article
2008[Jenkinson, Andrew M.]
Albrecht, Mario
[Birney, Ewan]
Blankenburg, Hagen
[Down, Thomas]
[Finn, Robert D.]
[Hermjakob, Henning]
[Hubbard, Tim J. P.]
[Jimenez, Rafael C.]
[Jones, Philip]
[Kähäri, Andreas]
[Kulesha, Eugene]
[Macías, José R.]
[Reeves, Gabrielle A.]
[Prlić, Andreas]
Integrating biological data - the Distributed Annotation System
In: BMC Bioinformatics [9], S3.1-7
Journal Article
2008Kircher, Martin
Bock, Christoph
Paulsen, Martina
Attachment IconStructural conservation versus functional divergence of maternally expressed microRNAs in the Dlk1/Gtl2 imprinting region
In: BMC Genomics [9], 346
Journal Article
2008[Lisurek, Michael]
[Simgen, Birgit]
Antes, Iris
[Bernhardt, Rita]
Theoretical and Experimental Evaluation of a CYP106A2 Low Homology Model and Production of Mutants with Changed Activity and Selectivity of Hydroxylation
In: ChemBioChem [9], 1439-1449
Journal Article
2008[Lucas, Simon]
[Heim, Ralph]
[Negri, Matthias]
Antes, Iris
[Ries, Christina]
[Schewe, Katarzyna E.]
[Bisi, Alessandra]
[Gobbi, Silvia]
[Hartmann, Rolf W.]
Novel Aldosterone Synthase Inhibitors with Extended Carbocyclic Skeleton by a Combined Ligand-Based and Structure-Based Drug Design Approach
In: Journal of Medical Chemistry [51], 6138-6149
Journal Article
2008Stop sign Icon[Moores, Andrew]
Thielen, Alexander
[Dong, Winnie]
Low, Andrew J.
[Woods, Conan]
[Jensen, Mark]
[Wynhoven, Brian]
[Chan, Dennison]
[Glascock, Christopher]
[Harrigan, P Richard]
Stop sign IconImproved detection of X4 virus by V3 genotyping: application to plasma RNA and proviral DNA
In: Antiviral Therapy, A99
Poster
2008Müller, FabianInferring virological response to antiretroviral combination therapy based on past treatment lines
Universität des Saarlandes
Thesis - Bachelor thesis
2008Stop sign Icon[Obermeier, Martin]
[Berg, Thomas]
[Sichtig, Nadine]
[Braun, Patrick]
[Däumer, Martin]
[Walter, Hauke]
[Noah, Christian]
[Wolf, Eva]
[Müller, Harm]
[Stürmer, Martin]
Thielen, Alexander
[Kaiser, Rolf]
Stop sign IconDetermination of HIV-1 co-receptor usage in German patients – comparison of genotypic methods with the TROFILE® phenotypic assay
In: Abstracts of the Ninth International Congress on Drug Therapy in HIV Infection, 123
Poster
2008Stop sign Icon[Obermeier, Martin]
[Sichtig, Nadine]
[Braun, Patrick]
[Däumer, Martin]
[Walter, Hauke]
[Noah, Christian]
[Wolf, Eva]
[Müller, Harm]
[Stürmer, Martin]
[Kaiser, Rolf]
Thielen, Alexander
Stop sign IconDetermination of HIV-1 coreceptor usage in German patients - comparison of genotypic methods with the TROFILE phenotypic assay
In: Antiviral Therapy, A112
Poster
2008Perner, JulianeAttachment IconSemi-Supervised Learning for Predicting Anti-HIV Drug Resistance
Universität des Saarlandes
Thesis - Bachelor thesis
2008[Rosen-Zvi, Michal]
Altmann, Andre
[Prosperi, Mattia]
[Aharoni, Ehud]
[Neuvirth, Hani]
[Sönnerborg, Anders]
[Schülter, Eugen]
[Struck, Daniel]
[Peres, Yardena]
[Incardona, Francesca]
[Kaiser, Rolf]
[Zazzi, Maurizio]
Lengauer, Thomas
Selecting anti-HIV therapies based on a variety of genomic and clinical factors
In: Proceedings of the 16th Annual International Conference on Intelligent Systems for Molecular Biology (ISMB 2008), i399-406
Proceedings Article
2008Stop sign Icon[Rosen-Zvi, Michal]
[Schülter, Eugen]
Altmann, Andre
[Sierra-Aragon, Saleta]
[Zazzi, Maurizio]
[Sönnerborg, Anders]
[Oette, Mark]
Lengauer, Thomas
[Kaiser, Rolf]
Stop sign IconSustaining lamivudine/emtricitabine, abacavir, zidovudine or atazanavir from a previous treatment shows a clinical benefit
In: Antiviral Therapy, A86
Poster
2008Saigo, Hiroto
[Tsuda, Koji]
[Giannotti, Fosca]
[Gunopulos, Dimitrios]
Iterative Subgraph Mining for Principal Component Analysis.
In: Proceedings of the IEEE International Conference on Data Mining (ICDM2008), DM934
Proceedings Article
2008Stop sign IconSander, Oliver
Altmann, Andre
Lengauer, Thomas
Stop sign IconComputational analysis of covariation and interactions between HIV-1 reverse transcriptase and Integrase
In: Reviews in Antiviral Therapy, 113-114
Poster
2008Sander, Oliver
Domingues, Francisco S.
Zhu, Hongbo
Lengauer, Thomas
Sommer, Ingolf
[Brazma, Alvis]
[Miyano, Satoru]
[Akutsu, Tatsuya]
Structural descriptors of protein-protein binding sites
In: Proceedings of 6th Asia-Pacific Bioinformatics Conference, 79-88
Proceedings Article
2008Schelhorn, Sven-Eric
Lengauer, Thomas
Albrecht, Mario
An integrative approach for predicting interactions of protein regions
In: Bioinformatics [24], i35-i41
Journal Article
2008Schlicker, Andreas
Albrecht, Mario
Attachment IconFunSimMat: a comprehensive functional similarity database
In: Nucleic Acids Research [36], D434-D439
Journal Article
2008[Sierra, Saleta]
[Kaiser, Rolf]
Thielen, Alexander
[Sander, Oliver]
Lengauer, Thomas
[Jäger, Hans]Genotypic Analysis of HIV Co-Receptor Usage
In: Entry Inhibitoren - Neue Formen der HIV-Therapie, 31-39
Part of a Book
2008Stöckel, DanielProtein Surface Remeshing and Characterisation Using Morse-Smale Complexes
Universität des Saarlandes
Thesis - Bachelor thesis
2008Stop sign IconThielen, Alexander
[Harrigan, P Richard]
Low, Andrew J.
[Moores, A]
Altmann, Andre
Bozek, Kasia
[Heger, Eva]
[Sichtig, Nadine]
[Kaiser, Rolf]
Lengauer, Thomas
Stop sign IconImproved genotypic prediction of HIV-1 coreceptor usage by incorporating V2 loop sequence variation
In: Antiviral Therapy, A100
Poster
2008Stop sign IconThielen, Alexander
[Kaiser, Rolf]
Lengauer, Thomas
Stop sign IconImproving HIV-1 coreceptor usage prediction from genotype with regions outside of V3
In: Reviews in Antiviral Therapy, 81-82
Poster
2008[Van Ooijen, Gerben]
Mayr, Gabriele
Albrecht, Mario
[Cornelissen, Ben J. C.]
[Takken, Frank L. W.]
Transcomplementation, but not physical association of the CC-NB-ARC and LRR domains of tomato R protein Mi-1.2 is altered by mutations in the ARC2 subdomain
In: Molecular Plant [1], 401-410
Journal Article
2008[Van Ooijen, Gerben]
Mayr, Gabriele
[Kasiem, Mobien M. A.]
Albrecht, Mario
[Cornelissen, Ben J. C.]
[Takken, Frank L. W.]
Structure-function analysis of the NB-ARC domain of plant disease resistance proteins
In: Journal of Experimental Botany [59], 1383-1397
Journal Article
2008Stop sign Icon[Verheyen, Jens]
Altmann, Andre
[Knops, Elena]
[Schülter, Eugen]
[Sichtig, Nadine]
[Reuter, Stefan]
[Fätkenheuer, Gerd]
[Pfister, Herbert]
[Kaiser, Rolf]
Stop sign IconRelevance of HIV gag cleavage site mutations in failures of protease inhibitor therapies
In: Antiviral Therapy, A53
Poster
2008[Watson, James D.]
[Thornton, Janet M.]
[Tress, Michael L.]
[Lopez, Gonzalo]
[Valencia, Alfonso]
[Redfern, Oliver]
[Orengo, Christine A.]
Sommer, Ingolf
Domingues, Francisco S.
[Frishman, Dmitrij]
[Valencia, Alfonso]
Structure to function
In: Modern Genome Annotation, 239-262
Part of a Book
2008Weinhold, Nils
Sander, Oliver
Domingues, Francisco S.
Lengauer, Thomas
Sommer, Ingolf
Attachment IconLocal function conservation in sequence and structure space
In: PLoS Computational Biology [4], e1000105
Journal Article
2008[Welsch, Christoph]
Domingues, Francisco S.
[Susser, Simone]
Antes, Iris
Hartmann, Christoph
Mayr, Gabriele
Schlicker, Andreas
[Sarrazin, Christoph]
Albrecht, Mario
[Zeuzem, Stefan]
Lengauer, Thomas
Attachment IconMolecular basis of telaprevir resistance due to V36 and T54 mutations in the NS3-4A protease of HCV
In: Genome Biology [9], R16
Journal Article
2008Zhu, Hongbo
Sommer, Ingolf
Lengauer, Thomas
Domingues, Francisco S.
Attachment IconAlignment of Non-Covalent Interactions at Protein-Protein Interfaces
In: PLoS ONE [3], e1926
Journal Article
2008Zotenko, Elena
Mestre, Julian
[O'Leary, Dianne]
[Przytycka, Teresa]
Why Do Hubs in the Yeast Protein Interaction Network Tend To Be Essential: Reexamining the Connection between the Network Topology and Essentiality
In: PLoS Computational Biology [4], e1000140
Journal Article
2007[Ahlenstiel, G.]
Roomp, Kirsten
Däumer, Martin
[Nattermann, T.]
[Vogel, M.]
[Rockstroh, J.K.]
Beerenwinkel, Niko
Kaiser, R.
[Nischalke, H.-D.]
[Sauerbruch, T.]
Lengauer, Thomas
[Spengler, U.]
Attachment IconSelective pressures of HLA genotypes and antiviral therapy on human immunodeficiency virus type 1 sequence mutation at a population level
In: Clinical and Vaccine Immunology [14], 1266-1273
Journal Article
2007Altmann, Andre
[Beerenwinkel, Niko]
Sing, Tobias
Savenkov, Igor
[Däumer, Martin]
[Kaiser, Rolf]
[Rhee, Soo-Yon]
[Fessel, W Jeffrey]
[Shafer, Robert W]
Lengauer, Thomas
Improved prediction of response to antiretroviral combination therapy using the genetic barrier to drug resistance
In: Antiviral Therapy [12], 169-178
Journal Article
2007Stop sign IconAltmann, Andre
[Däumer, Martin]
Sing, Tobias
[Beerenwinkel, Niko]
[Walter, Hauke]
[Kaiser, Rolf]
Lengauer, Thomas
Stop sign IconValidation of geno2pheno and THEO on a large independent clinical dataset
In: Proceedings of the 5th European HIV Drug Resistance Workshop, -
Poster
2007Stop sign IconAltmann, Andre
Sing, Tobias
[Vermeiren, Hans]
[Winters, Bart]
[Van Craenenbroeck, Elke]
[Van der Borght, Koen]
[Rhee, Soo-Yon]
[Shafer, Robert W]
[Schülter, Eugen]
[Kaiser, Rolf]
[Peres, Yardena]
[Sonnerborg, Anders]
[Fessel, W Jeffrey]
[Incardona, Francesca]
[Zazzi, Maurizio]
[Bacheler, Lee]
[Van Vlijmen, Hermann]
Lengauer, Thomas
Stop sign IconInferring virological response from genotype: with or without predicted phenotypes?
In: Proceedings of the 16th International HIV Drug Resistance Workshop, S169
Poster
2007Blankenburg, HagenA Distributed Annotation System for Molecular Interactions
Ruprecht Karl Universität Heidelberg; Universität Heilbronn
Thesis - other
2007Bock, Christoph
Lengauer, Thomas
Attachment IconComputational Epigenetics: Bioinformatik für neue Wege in der Krebsforschung
In: Jahrbuch 2007, 271-277
Part of a Book
2007Bock, Christoph
[Walter, Jörn]
[Paulsen, Martina]
Lengauer, Thomas
Attachment IconCpG Island Mapping by Epigenome Prediction
In: PLoS Computational Biology [3], 1055-1070
Journal Article
2007[Ceccherini-Silberstein, Francesca]
[Svicher, Valentina]
Sing, Tobias
[Artese, Anna]
[Santoro, Maria Mercedes]
[Forbici, Federica]
[Bertoli, Ada]
[Alcaro, Stefano]
[Palamara, Guido]
[Monforte, Antonella d'Arminio]
[Balzarini, Jan]
[Antinori, Andrea]
Lengauer, Thomas
[Perno, Carlo Federico]
Attachment IconCharacterization and structural analysis of novel mutations in human immunodeficiency virus type 1 reverse transcriptase involved in the regulation of restistance to nonnucleoside inhibitors
In: Journal of Virology [81], 11507-11519
Journal Article
2007Domingues, Francisco S.
Lengauer, Thomas
Lengauer, ThomasInferring Protein Function from Protein Structure
In: Bioinformatics - From Genomes to Therapies 3. The Holy Grail: Molecular Function, 1211-1252
Part of a Book
2007Domingues, Francisco S.
[Rahnenführer, Jörg]
Lengauer, Thomas
Conformational analysis of alternative protein structures
In: Bioinformatics [23], 3131-3138
Journal Article
2007Stop sign IconEmig, DorotheaStop sign IconThe Impact of Alternative Splicing on Protein Interaction Networks
Eberhard Karls Universität Tübingen
Thesis - other
2007[Flockerzi, Aline]
Maydt, Jochen
[Frank, Oliver]
[Ruggieri, Alessia]
[Maldener, Esther]
[Seifarth, Wolfgang]
[Medstrand, Patrik]
Lengauer, Thomas
[Meyerhans, Andreas]
[Leib-Mosch, Christine]
[Meese, Eckart]
[Mayer, Jens]
Attachment IconExpression pattern analysis of transcribed HERV sequences is complicated by ex vitvo recombination
In: Retrovirology [4], 39
Journal Article
2007[Franke, Andre]
[Hampe, Jochen]
[Rosenstiel, Philip]
[Becker, Christoph]
[Wagner, Florian]
[Häsler, Robert]
[Little, Randall D.]
[Huse, Klaus]
[Ruether, Andreas]
[Balschun, Tobias]
[Wittig, Michael]
[ElSharawy, Abdou]
Mayr, Gabriele
Albrecht, Mario
[Prescott, Natalie J.]
[Onnie, Clive M.]
[Fournier, Hélène]
[Keith, Tim]
[Radelof, Uwe]
[Platzer, Matthias]
[Mathew, Christopher G.]
[Stoll, Monika]
[Krawczak, Michael]
[Nürnberg, Peter]
[Schreiber, Stefan]
Systematic association mapping identifies NELL1 as a novel IBD disease gene
In: PLoS ONE [2], e691.1-13
Journal Article
2007[Hampe, Jochen]
[Franke, Andre]
[Rosenstiel, Philip]
[Till, Andreas]
[Teuber, Markus]
[Huse, Klaus]
Albrecht, Mario
Mayr, Gabriele
[De La Vega, Francisco M.]
[Briggs, Jason]
[Günther, Simone]
[Prescott, Natalie J.]
[Onnie, Clive M.]
[Häsler, Robert]
[Sipos, Bence]
[Fölsch, Ulrich R.]
Lengauer, Thomas
[Platzer, Matthias]
[Mathew, Christopher G.]
[Krawczak, Michael]
[Schreiber, Stefan]
A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1
In: Nature Genetics [39], 207-211
Journal Article
2007Hartmann, Christoph
Antes, Iris
Lengauer, Thomas
Attachment IconIRECS: A new algorithm for the selection of most probable ensembles of side-chain conformations in protein models.
In: Protein Science [16], 1294-1307
Journal Article
2007[Hofmann, Wolf Peter]
[Fernandez, B.]
[Herrmann, E.]
Welsch, Christoph
[Mihm, Ulrike]
[Kronenberg, B.]
[Feldmann, G.]
[Spengler, U.]
[Zeuzem, Stefan]
[Sarrazin, Christoph]
Somatic hypermutation and mRNA expression levels of the BCL-6 gene in patients with hepatitis C virus-associated lymphoproliferative diseases
In: Journal of Viral Hepatitis [14], 484-491
Journal Article
2007[Hofmann, Wolf Peter]
Welsch, Christoph
[Takahashi, Yoshitomo]
[Miyajima, Hiroaki]
[Mihm, Ulrike]
[Krick, Christoph]
[Zeuzem, Stefan]
[Sarrazin, Christoph]
Identification and in silico characterization of a novel compound heterozygosty associated with hereditary aceruloplasminemia
In: Scandinavian Journal of Gastroenterology [42], 1088-1094
Journal Article
2007Kämper, Andreas
[Rognan, Didier]
Lengauer, Thomas
Lengauer, ThomasLead Identification by Virtual Screening
In: Bioinformatics - From Genomes to Therapies 2. Getting at the Inner Workings: Molecular Interactions, 651-704
Part of a Book
2007[Ketter, Ralf]
[Kim, Yoo-Jin]
[Storck, Simone]
Rahnenführer, Jörg
[Romeike, Bernd F.M.]
[Steudel, Wolf-Ingo]
[Zang, Klaus D.]
[Henn, Wolfram]
Attachment IconHyperdiploidy defines a distinct cytogenetic entity of meningiomas
In: Journal of Neuro-Oncology [83], 213-221
Journal Article
2007[Ketter, Ralf]
[Urbschat, Steffi]
[Henn, Wolfram]
[Feiden, Wolfgang]
Beerenwinkel, Niko
Lengauer, Thomas
[Steudel, Wolf-Ingo]
[Zang, Klaus D.]
Rahnenführer, Jörg
Application of oncogenetic trees mixtures as a biostatistical model of the clonal cytogenetic evolution of meningiomas
In: International Journal of Cancer [121], 1473-1480
Journal Article
2007[Kupfer, Bernd]
Sing, Tobias
Schüffler, Peter
[Hall, Rabea]
[Kurz, Ralf]
[McKeown, Astrid]
[Schneweis, Karl-Eduard]
[Eberl, Wolfgang]
[Oldenburg, Johannes]
[Brackmann, Hans H.]
[Rockstroh, Jürgen K.]
[Spengler, Ulrich]
Däumer, Martin
[Kaiser, Rolf]
Lengauer, Thomas
[Matz, Bertfried]
Fifteen years of env C2V3C3 evolution in six individuals clonally infected with human immunodeficiency virus type 1
In: Journal of Medical Virology [79], 1629-1639
Journal Article
2007Lengauer, ThomasBioinformatics - From Genomes to Therapies 1. The Building Blocks: Molecular Sequences and StructuresBook
2007Lengauer, ThomasBioinformatics - From Genomes to Therapies 2. Getting at the Inner Workings: Molecular InteractionsBook
2007Lengauer, ThomasBioinformatics - From Genomes to Therapies 3. The Holy Grail: Molecular FunctionBook
2007Lengauer, ThomasBullinger, H.J.Bioinformatik
In: Technologiefüher - Grundlagen, Anwendungen, Trends, 4
Part of a Book
2007Lengauer, ThomasLengauer, ThomasFuture Trends
In: Bioinformatics - From Genomes to Therapies 3. The Holy Grail: Molecular Function, 1651-1687
Part of a Book
2007Lengauer, ThomasLengauer, ThomasIntroduction
In: Bioinformatics - From Genomes to Therapies 1. The Building Blocks: Molecular Sequences and Structures, 1-24
Part of a Book
2007Lengauer, Thomas
[Oette, M.]
[Selbig, J.]
[Hoffmann, D.]
[Poggensee, G.]
[Hamouda, O.]
[Häussinger, D.]
[Kaiser, R.]
European Journal of Medical ResearchJournal
2007Lengauer, ThomasReuse, Bernd
Vollmar, Roland
Strategiekonzept "Molekulare Bioinformatik"
In: Informatikforschung in Deutschland, 9
Part of a Book
2007Lengauer, Thomas
[Rost, B.]
[Schuster, P.]
Proceedings ISMB2007Proceedings
2007Lengauer, Thomas
Sander, Oliver
[Sierra, Saleta]
Thielen, Alexander
[Kaiser, Rolf]
Bioinformatics prediction of HIV coreceptor usage
In: Nature Biotechnology [25], 1407-1410
Journal Article
2007[Liu, Fang]
[Tostesen, Eivind]
[Sundet, Jostein K.]
[Jenssen, Tor-Kristian]
Bock, Christoph
[Jerstad, Geir Ivar]
[Thilly, William G.]
[Hovig, Eivind]
Attachment IconThe human genomic melting map
In: PLoS Computational Biology [3], e93
Journal Article
2007[Low, Andrew J.]
[Dong, Winnie]
[Chan, Dennison]
Sing, Tobias
[Swanstrom, Ronald]
[Jensen, Mark]
[Pillai, Satish]
[Good, Benjamin]
[Harrigan, P. Richard]
Current V3 genotyping algorithms are inadequate for predicting X4 co-receptor usage in clinical isolates
In: AIDS [21], F19-F26
Journal Article
2007Mayr, Gabriele
Domingues, Francisco S.
[Lackner, Peter]
Attachment IconComparative Analysis of Protein Structure Alignments
In: BMC Structural Biology [7], 1
Journal Article
2007[Mikeska, Thomas]
Bock, Christoph
[El-Maarri, Osman]
[Hübner, Anika]
[Ehrentraut, Denise]
[Schramm, Johannes]
[Felsberg, Jörg]
[Kahl, Philip]
[Büttner, Reinhard]
[Pietsch, Torsten]
[Waha, Andreas]
Attachment IconOptimization of Quantitative MGMT Promoter Methylation Analysis Using Pyrosequencing and Combined Bisulfite Restriction Analysis
In: Journal of Molecular Diagnostics [9], 368-381
Journal Article
2007Rahnenführer, Jörg
Lengauer, Thomas
Lengauer, ThomasAnalysis of Expression Data: Classification of genes
In: Bioinformatics - From Genomes to Therapies 2. Getting at the Inner Workings: Molecular Interactions, 993-1021
Part of a Book
2007Ramírez, Fidel
Schlicker, Andreas
Assenov, Yassen
Lengauer, Thomas
Albrecht, Mario
Computational analysis of human protein interaction networks
In: Proteomics [7], 2541-2552
Journal Article
2007Roomp, KirstenLengauer, ThomasEvolution of Drug Resistance in HIV
In: Bioinformatics - From Genomes to Therapies 3. The Holy Grail: Molecular Function, 1457-1496
Part of a Book
2007[Salamat-Miller, Nazila]
[Fang, Jianwen]
[Seidel, Christopher W.]
Assenov, Yassen
Albrecht, Mario
[Middaugh, C. Russell]
Attachment IconA network-based analysis of polyanion-binding proteins utilizing human protein arrays
In: Journal of Biological Chemistry [282], 10153-10163
Journal Article
2007Sander, Oliver
Sing, Tobias
Sommer, Ingolf
[Low, Andrew J.]
[Cheung, Peter K.]
[Harrigan, P. Richard]
Lengauer, Thomas
Domingues, Francisco S.
Attachment IconStructural Descriptors of gp120 V3 Loop for the Prediction of HIV-1 Coreceptor Usage
In: PLoS Computational Biology [3], 555-564
Journal Article
2007[Scheller, Nicoletta]
[Resa-Infante, Patricia]
[de la Luna, Susana]
[Galao, Rui Pedro]
Albrecht, Mario
[Kaestner, Lars]
[Lipp, Peter]
Lengauer, Thomas
[Meyerhans, Andreas]
[Díez, Juana]
Identification of PatL1, a human homolog to yeast P body component Pat1
In: Biochimica et Biophysica Acta - Molecular Cell Research [1773], 1786-1792
Journal Article
2007Schlicker, Andreas
Huthmacher, Carola
Ramírez, Fidel
Lengauer, Thomas
Albrecht, Mario
Attachment IconFunctional evaluation of domain-domain interactions and human protein interaction networks
In: Bioinformatics [23], 859-865
Journal Article
2007[Schulz, Wolfgang A.]
Alexa, Adrian
[Jung, Volker]
[Hader, Christiane]
[Hoffmann, Michele J.]
[Yamanaka, Masanori]
[Fritzsche, Sandy]
[Wlazlinski, Agnes]
[Müller, Mirko]
Lengauer, Thomas
[Engers, Rainer]
[Florl, Andrea R.]
[Wullich, Bernd]
Rahnenführer, Jörg
Attachment IconFactor interaction analysis for chromosome 8 and DNA methylation alterations highlights innate immune response suppression and cytoskeletal changes in prostate cancer
In: Molecular Cancer [6], 1-16
Journal Article
2007[Sierra, Saleta]
[Kaiser, Rolf]
Thielen, Alexander
Lengauer, Thomas
Attachment IconGenotypic coreceptor analysis.
In: European Journal of Medical Research [12], 453-462
Journal Article
2007Sing, Tobias
[Beerenwinkel, Niko]
[Schölkopf, B]
[Platt, J.]
[Hoffman, T.]
Attachment IconMutagenetic tree Fisher kernel improves prediction of HIV drug resistance from viral genotype
In: Advances in Neural Information Processing Systems 19, 1-9
Proceedings Article
2007Sing, Tobias
Low, Andrew J.
Beerenwinkel, Niko
Sander, Oliver
[Cheung, Peter K.]
Domingues, Francisco S.
Büch, Joachim
[Däumer, Martin]
[Kaiser, Rolf]
Lengauer, Thomas
[Harrigan, P. Richard]
Predicting HIV coreceptor usage on the basis of genetic and clinical covariates
In: Antiviral Therapy [12], 1097-1106
Journal Article
2007[Skrabal, Katharina]
[Low, Andrew J.]
[Dong, Winnie]
Sing, Tobias
[Cheung, Peter K.]
[Mammano, Fabrizio]
[Harrigan, P. Richard]
Attachment IconDetermining human immunodeficiency virus coreceptor use in a clinical setting: Degree of correlation between two phenotypic assays and a bioinformatic model
In: Journal of Clinical Microbiology [45], 279-284
Journal Article
2007[Söderhäll, Cilla]
[Marenholz, Ingo]
[Kerscher, Tamara]
[Rüschendorf, Franz]
[Esparza-Gordillo, Jorge]
[Worm, Margitta]
[Gruber, Christoph]
Mayr, Gabriele
Albrecht, Mario
[Rohde, Klaus]
[Schulz, Herbert]
[Wahn, Ulrich]
[Hubner, Norbert]
[Lee, Young-Ae]
Attachment IconVariants in a novel epidermal collagen gene (COL29A1) are associated with atopic dermatitis
In: PLoS Biology [5], e242.1952-1961
Journal Article
2007Sommer, IngolfLengauer, ThomasProtein Fold Recognition Based on Distant Homologs
In: Bioinformatics - From Genomes to Therapies 1. The Building Blocks: Molecular Sequences and Structures, 351-388
Part of a Book
2007Sommer, Ingolf
Müller, Oliver
Domingues, Francisco S.
Sander, Oliver
[Weickert, Joachim]
Lengauer, Thomas
Moment invariants as shape recognition technique for comparing protein binding sites
In: Bioinformatics [23], 3139-3146
Journal Article
2007Steffen, Andreas
[Karasz, Maximilian]
[Thiele, Carolin]
Lengauer, Thomas
Kämper, Andreas
[Wenz, Gerhard]
[Apostolakis, Joannis]
Combined similarity and QSPR virtual screening for guest molecules of $\beta$-cyclodextrin
In: New Journal of Chemistry [31], 1941-1949
Journal Article
2007Steffen, Andreas
[Thiele, Carolin]
[Tietze, Simon]
[Strassnig, Christian]
Kämper, Andreas
Lengauer, Thomas
[Wenz, Gerhard]
[Apostolakis, Joannis]
Improved cyclodextrin-based receptors for camptothecin by inverse virtual screening
In: Chemistry [13], 6801-6809
Journal Article
2007[Tress, Michael L.]
[Martelli, Pier L.]
[Frankish, Adam]
[Reeves, Gabrielle A.]
[Wesselink, Jan J.]
[Yeats, Corin]
[Ólason, Páll Í.]
Albrecht, Mario
[Hegyi, Hedi]
[Giorgetti, Alejandro]
[Raimondo, Domenico]
[Lagarde, Julien]
[Laskowski, Roman A.]
[López, Gonzalo]
[Sadowski, Michael I.]
[Watson, James D.]
[Fariselli, Piero]
[Rossi, Ivan]
[Nagy, Alinda]
[Kai, Wang]
[Størling, Zenia]
[Orsini, Massimiliano]
Assenov, Yassen
Blankenburg, Hagen
Huthmacher, Carola
Ramírez, Fidel
Schlicker, Andreas
[Denoued, France]
[Jones, Phil]
[Kerrien, Samuel]
[Orchard, Sandra]
[Antonarakis, Stylianos E.]
[Reymond, Alexandre]
[Birney, Ewan]
[Brunak, Søren]
[Casadio, Rita]
[Guigo, Roderic]
[Harrow, Jennifer]
[Hermjakob, Henning]
[Jones, David T.]
Lengauer, Thomas
[Orengo, Christine A.]
[Patthy, László]
[Thornton, Janet M.]
[Tramontano, Anna]
[Valencia, Alfonso]
Attachment IconThe implications of alternative splicing in the ENCODE protein complement
In: Proceedings of the National Academy of Sciences [104], 5495-5500
Journal Article
2007[Welker, Martin W.]
[Hofmann, Wolf-Peter]
[Welsch, Christoph]
[von Wagner, Michael]
[Herrmann, Eva]
[Lengauer, Thomas]
[Zeuzem, Stefan]
[Sarrazin, Christoph]
Correlation nonstructural (NS)4B amino acid variations with initial viral kinetics during interferon-alpha-based therapy in HCV-1b-infected patients
In: Journal of Viral Hepatitis [14], 338-349
Journal Article
2007Welsch, Christoph
Albrecht, Mario
Maydt, Jochen
[Herrmann, E.]
[Welker, M.W.]
[Sarrazin, C.]
[Scheidig, A.]
Lengauer, Thomas
Zeuzem, S.
Structural and functional comparison of the non-structural protein 4B of flaviviridae
In: Journal of Molecular Graphics and Modeling [26], 546-557
Journal Article
2007Stop sign Icon[Zazzi, Maurizio]
[Aharoni, Ehud]
[Altmann, Andre]
[Baszó, Fulop]
[Bidgood, Penny]
[Borgulya, Gabór]
[Denholm-Prince, J]
[Fielder, M]
[Kaiser, Rolf]
[Kent, Carmel]
[Lengauer, Thomas]
[Nepusz, T]
[Neuvirth, Hanni]
[Peres, Yardena]
[Petroczi, Andrea]
[Prosperi, Mattia]
[Romano, L]
[Rosen-Zvi, Michal]
[Schülter, Eugen]
Sing, Tobias
[Sonnerborg, Andras]
[Thompson, R]
[Ulivi, G]
[Zalány, L]
[Incardona, Francesca]
Stop sign IconEuResist: exploration of multiple modeling techniques for prediction of response to treatment
In: Proceedings of the 5th European HIV Drug Resistance Workshop, -
Poster
2006Albrecht, Mario
[Takken, Frank L. W.]
Update on the domain architectures of NLRs and R proteins
In: Biochemical and Biophysical Research Communications [339], 459-462
Journal Article
2006Alexa, Adrian
Rahnenführer, Jörg
Lengauer, Thomas
Attachment IconImproved Scoring of Functional Groups from Gene Expression Data by Decorrelating GO Graph Structure
In: Bioinformatics [22], 1600-1607
Journal Article
2006Stop sign IconAntes, Iris
Lengauer, Thomas
Stop sign IconRefinement of homology modeled protein structures for molecular docking
In: Proceedings of the 367. WE-Heraeus Seminar on Biomolecular Simulations, 1
Poster
2006Antes, Iris
Siu, Shirley Weng-In
Lengauer, Thomas
Attachment IconDynaPred: A structure and sequence based method for the prediction of MHC class I binding peptide sequence and conformations
In: Bioinformatics [22], 16-24
Journal Article
2006Bock, ChristophBioinformatik: Neue Strategien gegen Krebs
In: Deutsches Ärzteblatt PRAXiS [103], 10-11
Journal Article
2006Bock, Christoph
Halachev, Konstantin
Lengauer, Thomas
[Haasis, Klaus]
[Heinzl, Armin]
[Klumpp, Dieter]
Bioinformatisches Data Mining erschließt neue Strategien gegen Krebs
In: Aktuelle Trends in der Softwareforschung, 91-99
Part of a Book
2006Bock, Christoph
[Hesser, Jürgen]
Attachment IconAnalysis and Prediction of Helix Shift Errors in Homology Modeling
In: In Silico Biology [6], 131-145
Journal Article
2006[Boeddrich, Annett]
[Gaumer, Sébastien]
[Haacke, Annette]
[Tzvetkov, Nikolay]
Albrecht, Mario
[Evert, Bernd O.]
[Müller, Eva C.]
[Lurz, Rudi]
[Breuer, Peter]
[Schugardt, Nancy]
[Plaßmann, Stephanie]
[Xu, Kexiang]
[Warrick, John M.]
[Suopanki, Jaana]
[Wüllner, Ullrich]
[Frank, Ronald]
[Hartl, Ulrich F.]
[Bonini, Nancy M.]
[Wanker, Erich E.]
An arginine/lysine-rich motif is crucial for VCP/p97-mediated modulation of ataxin-3 fibrillogenesis
In: EMBO Journal [25], 1547-1558
Journal Article
2006Stop sign IconFrings, OliverStop sign IconDevelopment of a
Smith-Waterman-Like Multi-Aspect
Alignment Tool
Universität des Saarlandes
Thesis - Bachelor thesis
2006Stop sign IconGlaab, EnricoStop sign IconOn the predictability of CpG methylation in human tissue at single basepair resolution
Universität des Saarlandes
Thesis - Bachelor thesis
2006[Heckmann-Pohl, Dorothee M.]
[Bastian, Sabine]
[Altmeier, S.]
Antes, Iris
Improvement of the fungal enzyme pyranose 2-oxidase using protein engineering
In: Journal of Biotechnology [124], 26-40
Journal Article
2006[Heil, Burkhard]
[Ludwig, Jost]
[Lichtenberg-Fraté, Hella]
Lengauer, Thomas
Computational recognition of potassium channel sequences
In: Bioinformatics [13], 1562-1568
Journal Article
2006Stop sign IconHobler, AnnaStop sign IconDocking of monosaccharids into the wild type and mutants of pyranose 2-oxidase
Universität des Saarlandes
Thesis - Bachelor thesis
2006Huthmacher, CarolaDecomposing Protein Networks Into
Domain-Domain Interactions
Eberhard Karls University Tübingen
Thesis - other
2006Stop sign IconJung, HolgerStop sign IconYamada Analyzer - A tool for fast calculation of genomic attributes
Universität des Saarlandes
Thesis - Bachelor thesis
2006Kämper, Andreas
[Apostolakis, Joannis]
[Rarey, Matthias]
[Marian, Christel Maria]
Lengauer, Thomas
Fully Automated Flexible Docking of Ligands into Flexible Synthetic Receptors Using Forward and Inverse Docking Strategies
In: Journal of Chemical Information and Modeling [46], 903-911
Journal Article
2006[Lehmann, Clara]
[Däumer, Martin]
[Bousaad, Ibrahim]
Sing, Tobias
[Beerenwinkel, Niko]
Lengauer, Thomas
[Schmeisser, Norbert]
[Wyen, Christoph]
[Fätkenheuer, Gerd]
[Kaiser, Rolf]
Stable coreceptor usage of HIV in patients with ongoing treatment failure on HAART
In: Journal of Clinical Virology [37], 300-304
Journal Article
2006Lengauer, Thomas
Domingues, F.S.
Sommer, Ingolf
Zhu, Hongbo
Analysis and prediction of protein-protein-interaction types
In: BMC Bioinformatics [7], -
Journal Article
2006Lengauer, Thomas
Sing, Tobias
Bioinformatics-assisted anti-HIV therapy
In: Nature Reviews Microbiology [4], 790-797
Journal Article
2006Maydt, Jochen
Lengauer, Thomas
Recco: recombination analysis using cost optimization
In: Bioinformatics [22], 1064-1071
Journal Article
2006[Mihm, Ulrike]
[Grigorian, Natalia]
[Welsch, Christoph]
[Herrmann, Eva]
[Kronenberger, Bernd]
[Teuber, Gerlinde]
[von Wagner, Michael]
[Hofmann, Wolf-Peter]
Albrecht, Mario
Lengauer, Thomas
[Zeuzem, Stefan]
[Sarrazin, Christoph]
Amino acid variations in hepatitis C virus p7 and sensitivity to antiviral combination therapy with amantadine in chronic hepatitis C
In: Antiviral Therapy [11], 507-519
Journal Article
2006[Neumann, Dirk]
[Kohlbacher, Oliver]
[Merkwirth, Christian]
Lengauer, Thomas
A Fully Computational Model for Predicting Percutaneous Drug Absorption
In: Journal of Chemical Information and Modeling [1], 424-429
Journal Article
2006Stop sign Icon[Neumann, Dirk]
[Kohlbacher, Oliver]
[Merkwirth, Christian]
Lengauer, Thomas
Stop sign IconPrediction of percutaneous drug absorption
In: Journal of Chemical Information and Modeling [1], 424-429
Journal Article
2006Stop sign IconPfeifer, SusanneStop sign IconDevelopment of a fast
geometry-based screening
compound prefiltering technique
Universität des Saarlandes
Thesis - Bachelor thesis
2006[Plotz, Guido]
[Welsch, Christoph]
[Giron-Monzon, Luis]
[Friedhoff, Peter]
Albrecht, Mario
[Piiper, Albrecht]
Biondi, Ricardo M.
Lengauer, Thomas
[Zeuzem, Stefan]
[Raedle, Jochen]
Attachment IconMutations in the MutSalpha interaction interface of MLH1 can abolish DNA mismatch repair
In: Nucleic Acids Research [34], 6574-6586
Journal Article
2006Stop sign IconReimer, DanielaStop sign IconDocking studies to investigate the effect of correlated mutations in the HIV-Protease on the drug resistance of HIV
Universität des Saarlandes
Thesis - Bachelor thesis
2006Roomp, Kirsten
Beerenwinkel, Niko
Sing, Tobias
[Schülter, Eugen]
Büch, Joachim
[Sierra-Aragon, Saleta]
[Däumer, Martin]
[Hoffmann, Daniel]
[Kaiser, Rolf]
Lengauer, Thomas
[Selbig, Joachim]
Arevir: A Secure Platform for Designing Personalized Antiretroviral Therapies Against HIV
In: Lecture Notes in Computer Science [4075], 185-194
Journal Article
2006[Salamat-Miller, Nazila]
[Fang, Jianwen]
[Seidel, Christopher W.]
[Smalter, Aaron M.]
[Assenov, Yassen]
Albrecht, Mario
[Middaugh, C. Russell]
A network-based analysis of polyanion-binding proteins utilizing yeast protein arrays
In: Molecular and Cellular Proteomics [5], 2263-2278
Journal Article
2006Schlicker, Andreas
Huthmacher, Carola
Ramírez, Fidel
Lengauer, Thomas
Albrecht, Mario
[Huson, Daniel]
[Kohlbacher, Oliver]
[Lupas, Andrei]
[Nieselt, Kay]
[Zell, Andreas]
Functional evaluation of domain-domain interactions and human protein interaction networks
In: German Conference on Bioinformatics (GCB 2006), 115-126
Proceedings Article
2006Sing, Tobias
Sander, Oliver
Beerenwinkel, Niko
Lengauer, Thomas
ROCR: Visualizing classifier performance in R
In: Bioinformatics [21], 3940-3941
Journal Article
2006Steffen, Andreas
Kämper, Andreas
Lengauer, Thomas
Flexible Docking of Ligands into Synthetic Receptors Using a Two-Sided Incremental Construction Algorithm
In: Journal of Chemical Information and Modeling [46], 1695-1703
Journal Article
2006Steffen, Andreas
Kämper, Andreas
Lengauer, Thomas
[Turner, Anthony P. F.]Virtual screening for guest molecules of a biosensor
In: Biosensors 2006: The ninth world congress on biosensors, O66
Proceedings Article
2006[Svicher, Valentina]
Sing, Tobias
[Santoro, Maria Mercedes]
[Forbici, Federica]
[Rodriguez- Barrios, Fátima]
[Bertoli, Ada]
[Beerenwinkel, Niko]
[Bellocchi, Maria Concetta]
[Gago, Federigo]
[d´Arminio Monforte, Antonella]
[Antinori, Andrea]
Lengauer, Thomas
Ceccherini-Silberstein, Francesca
[Perno, Carlo-Federico]
Involvement of novel HIV-1 reverse transcriptase mutations in the regulation of resistance to nucleoside inhibitors
In: Journal of Virology [80], 7186-7198
Journal Article
2006Takken, Frank L. W.
Albrecht, Mario
[Tameling, Wladimir I.]
Resistance proteins: molecular switches of plant defence
In: Current Opinion in Plant Biology [9], 383-390
Journal Article
2006Talwar, Priti
Lengauer, Thomas
[Wittmann, Christoph]
[Velagapudi, V. R.]
[Heinzle, Elmar]
Development of Computational Methods for Analysis of Metabolic Profiling Data
In: Proceedings of International Conference on Systems Biology (ICSB 2006), Japan, 42-42
Proceedings Article
2006[Tameling, Wladimir I.]
[Vossen, Jack H.]
Albrecht, Mario
Lengauer, Thomas
[Berden, Jan A.]
[Haring, Michel A.]
[Cornelissen, Ben J.C.]
Takken, Frank L. W.
Mutations in the NB-ARC domain of I-2 that impair ATP hydrolysis cause autoactivation
In: Plant Physiology [140], 1233-1245
Journal Article
2006Stop sign Icon[Torda, Andrew E.]
Lengauer, Thomas
Stop sign IconAttachment IconEditorial: Selection of papers of the German Conference of Bioinformatics (GCB) 2005
In: Bioinformatics [22], 1
Journal Article
2006[Velagapudi, Vidya R.]
[Wittmann, Christoph]
Lengauer, Thomas
Talwar, Priti
[Heinzle, Elmar]
Metabolic high- content screening of Saccharomyces cerevisiae reveals superior performance of single gene deletion strains
In: Process Biochemistry [41], 2170-2179
Journal Article
2006[Verheyen, Jens]
[Litau, Elena]
Sing, Tobias
[Däumer, Martin]
[Balduin, Melanie]
[Oette, Mark]
[Fätkenheuer, Gerd]
[Rockstroh, Jürgen K.]
[Schuldenzucker, Ulrike]
[Hoffmann, Daniel]
[Pfister, Herbert]
[Kaiser, Rolf]
Compensatory mutations at the HIV cleavage sites p7/p1 and p1/p6-gag in therapy-naive and therapy-experienced patients
In: Antiviral Therapy [11], 879-887
Journal Article
2006[Voets, Marieke]
Antes, Iris
[Scherer, Christiane]
[Müller-Vieira, Ursula]
[Biemel, Klaus]
[Marchais-Oberwinkler, Sandrine]
[Hartmann, Rolf W.]
Synthesis and evaluation of heteroaryl substituted dihydronaphthalenes and indenes: potent and selective inhibitors of aldosterone synthase (CYP11B2) for the treatment of congestive heart failure and myocardial fibrosis
In: Journal of Medicinal Chemistry [49], 2222-2231
Journal Article
2006[Yin, Junming]
[Beerenwinkel, Niko]
Rahnenführer, Jörg
Lengauer, Thomas
Attachment IconModel Selection for Mixtures of Mutagenetic Trees
In: Statistical Applications in Genetics and Molecular Biology [5], Article 17
Journal Article
2006Stop sign IconZimmer, TobiasStop sign IconFunctional Site Scaffolds
Universität des Saarlandes
Thesis - Bachelor thesis
2005Albrecht, MarioLRRK2 mutations and parkinsonism
In: The Lancet [365], 1230
Journal Article
2005Albrecht, Mario
[Choubey, Divaker]
Lengauer, Thomas
The HIN domain of IFI-200 proteins consists of two OB folds
In: Biochemical and Biophysical Research Communications [327], 679-687
Journal Article
2005Albrecht, Mario
Huthmacher, Carola
[Tosatto, Silvio C.E.]
Lengauer, Thomas
Decomposing protein networks into domain-domain interactions
In: Bioinformatics [21], ii220-ii221
Journal Article
2005Antes, Iris
Merkwirth, Christian
Lengauer, Thomas
POEM: Parameter Optimization using Ensemble Methods: Application to target specific scoring functions
In: Journal of Chemical Information and Modeling [45], 1291-1302
Journal Article
2005[Balduin, Melanie]
Beerenwinkel, Niko
[Sierra, Saleta]
[Däumer, Martin]
[Rockstroh, Jürgen]
[Oette, Mark]
[Fätkenheuer, Gerd]
[Kupfer, Bernd]
[Hoffmann, Daniel]
[Selbig, Joachim]
[Pfister, Herbert]
[Kaiser, Rolf]
Evolution of HIV resistance during treatment interruption in experienced patients and after restarting a new therapy
In: J Clin Virol [34], 277-287
Journal Article
2005Beerenwinkel, Niko
[Däumer, Martin]
Sing, Tobias
Rahnenführer, Jörg
Lengauer, Thomas
[Selbig, Joachim]
[Hoffmann, Daniel]
[Kaiser, Rolf]
Estimating HIV evolutionary pathways and the genetic barrier to drug resistance
In: The Journal of Infectious Diseases [191], 1953-1960
Journal Article
2005Beerenwinkel, Niko
Rahnenführer, Jörg
[Däumer, Martin]
[Hoffmann, Daniel]
[Kaiser, Rolf]
[Selbig, Joachim]
Lengauer, Thomas
Learning multiple evolutionary pathways from cross-sectional data
In: Journal of Computational Biology [12], 584-598
Journal Article
2005Beerenwinkel, Niko
Rahnenführer, Jörg
[Kaiser, Rolf]
[Hoffmann, Daniel]
[Selbig, Joachim]
Lengauer, Thomas
Mtreemix: a software package for learning and using mixture models of mutagenetic trees
In: Bioinformatics [21], 2106-2107
Journal Article
2005[Beerenwinkel, Niko]
Sing, Tobias
Lengauer, Thomas
Rahnenführer, Jörg
Roomp, Kirsten
Savenkov, Igor
[Fischer, Roman]
[Hoffmann, Daniel]
[Selbig, Joachim]
[Korn, Klaus]
[Walter, Hauke]
[Berg, Thomas]
[Braun, Patrick]
[Fätkenheuer, Gerd]
[Oette, Mark]
[Rockstroh, Jürgen]
[Kupfer, Bernd]
[Kaiser, Rolf]
[Däumer, Martin]
Computational methods for the design of effective therapies against drug resistant HIV strains
In: Bioinformatics [21], 3943-3950
Journal Article
2005Bock, Christoph
Lengauer, Thomas
[Reither, Sabine]
[Mikeska, Thomas]
[Paulsen, Martina]
[Walter, Jörn]
Attachment IconBiQ Analyzer: visualization and quality control for DNA methylation data from bisulfite sequencing
In: Bioinformatics [21], 4067-4068
Journal Article
2005[Bojunga, Jörg]
[Welsch, Christoph]
Antes, Iris
Albrecht, Mario
Lengauer, Thomas
[Zeuzem, Stefan]
Structural and functional analysis of a novel mutation of CYP21B in a heterozygote carrier of 21-hydroxylase deficiency
In: Human Genetics [117], 558-564
Journal Article
2005[Castellano, Sergi]
[Lobanov, Alexey V.]
[Chapple, Charles]
[Novoselov, Sergey V.]
Albrecht, Mario
[Hua, Deame]
[Lescure, Alain]
Lengauer, Thomas
[Krol, Alain]
[Gladyshev, Vadim N.]
[Guigó, Roderic]
Diversity and functional plasticity of eukaryotic selenoproteins: Identification and characterization of the SelJ family
In: Proceedings of the National Academy of Sciences [102], 16188-16193
Journal Article
2005[Costello, Christine M.]
[Mah, Nancy]
[Häsler, Robert]
[Rosenstiel, Philip]
[Waetzig, Georg H.]
Hahn, Andreas
[Lu, Tim]
[Gurbuz, Yesim]
[Nikolaus, Susanna]
Albrecht, Mario
[Hampe, Jochen]
[Lucius, Ralph]
[Klöppel, Günther]
[Eickhoff, Holger]
[Lehrach, Hans]
Lengauer, Thomas
[Schreiber, Stefan]
Dissection of the inflammatory bowel disease transcriptome using genome-wide cDNA microarrays identifies novel candidate disease genes
In: PLoS Medicine [2], 771-787
Journal Article
2005[Das, Ani V.]
[James, Jackson]
Rahnenführer, Jörg
[Thoresona, Wallace B.]
[Bhattacharyaa, Sumitra]
[Zhao, Xing]
[Ahmad, Iqbal]
Retinal properties and potential of the adult mammalian ciliary epithelium stem cells
In: Vision Research [45], 1653-1666
Journal Article
2005Djoumbou, YannickDocking studies to investigate the effect of correlated mutations in the HIV-Protease on the drug resistance of HIV
Universität des Saarlandes
Thesis - Bachelor thesis
2005[Gu, Wei]
[Kofler, Michael]
Antes, Iris
[Freund, Christian]
[Helms, Volkhard]
Alternative Binding Modes of Polyproline Peptides Binding to the GYF Domain
In: Biochemistry [44], 6404-6415
Journal Article
2005Hahn, Andreas
Rahnenführer, Jörg
Talwar, Priti
Lengauer, Thomas
Confirmation of human protein interaction data by human expression data
In: BMC Bioinformatics [6], 1-11
Journal Article
2005[Hessler, G.]
[Zimmermann, M.]
[Matter, H.]
[Evers, A.]
[Naumann, T.]
Lengauer, Thomas
[Rarey, M.]
Multiple-Ligand-Based Virtual Screening: Methods and Applications of the MTree Approach
In: Journal of Medicinal Chemistry [48], 6575-6584
Journal Article
2005Immesberger, StefanAttachment IconA Prefiltering Method to Speed up Protein
Structure Prediction
Universität des Saarlandes
Thesis - Bachelor thesis
2005Kämper, Andreas
Kaspar, Melanie
Lengauer, Thomas
Efficient conformational analysis of synthetic receptors with macrocyclic and fused ring systems
In: Synthetic Receptors 2005: Second World Congress on Synthetic Receptors, O4
Proceedings Article
2005[Kaiser, Rolf]
[Boussaad, Ibo]
[Lehmann, C.]
[Däumer, Martin]
Sing, Tobias
[Schmeisser, N.]
[Wyen, C.]
Fätkenheuer, Gerd
Stable coreceptor usage of HIV-1 in patients with ongoing treatment failure on HAART
In: Proceedings of the 3rd European HIV Drug Resistance Workshop, -
Proceedings Article
2005Kaspar, MelanieAttachment IconConformational Analysis of Macrocyclic Ring Systems
Universität des Saarlandes
Thesis - Bachelor thesis
2005Krier, MarkusAttachment IconMotif Search in Protein Sequences for Protein
Structure Prediction
Universität des Saarlandes
Thesis - Bachelor thesis
2005Lengauer, Thomas
Albrecht, Mario
[Sarrazin, C.]
[Mihm, U.]
[Herrmann, E.]
Welsch, Christoph
[Sarrazin, U.]
[Traver, S.]
[Zeuzem, S.]
Replication enhancing mutations of the Hepatitis C virus replicon: Prevalence and clinical significance in patients with chronic Hepatitis C
In: Journal of Infectious Diseases [192], 1710-1719
Journal Article
2005Lengauer, Thomas
[Merkwirth, Christian]
Automatic Generation of complementary descriptors with molecular graph networks
In: Journal of Chemical Information and Modeling [45], 1159-1168
Journal Article
2005Lengauer, Thomas[Meyers, Robert A.]Attachment IconInformatics (Computational Biology)
In: Growth Factors and Oncogenes in Gastrointestinal Cancers to Informatics (Computational Biology), 567-626
Part of a Book
2005Meiser, InaIdentification of functionally important regions in cytochrome P450 systems and a systematic analysis of various CYP P450 homology models
Universität des Saarlandes
Thesis - Bachelor thesis
2005Nickels, StefanAttachment IconGenerating Molecular Hashcodes for
Finding Duplicates in Virtual Screening
Libraries
Universität des Saarlandes
Thesis - Bachelor thesis
2005Rahnenführer, JörgClustering algorithms and other exploratory methods for microarray data analysis
In: Methods of Information in Medicine [44], 444-448
Journal Article
2005Rahnenführer, JörgImage analysis for cDNA microarrays
In: Methods of Information in Medicine [44], 405-407
Journal Article
2005Rahnenführer, Jörg
Beerenwinkel, Niko
[Schulz, Wolfgang A.]
[Hartmann, Christian]
[von Deimling, Andreas]
[Wullich, Bernd]
Lengauer, Thomas
Estimating cancer survival and clinical outcome based on genetic tumor progression scores
In: Bioinformatics [21], 2438-2446
Journal Article
2005[Ralser, Markus]
Albrecht, Mario
[Nonhoff, Ute]
Lengauer, Thomas
[Lehrach, Hans]
[Krobitsch, Sylvia]
An integrative approach to gain insights into the cellular function of human ataxin-2
In: Journal of Molecular Biology [346], 203-214
Journal Article
2005[Ralser, Markus]
[Nonhoff, Ute]
Albrecht, Mario
Lengauer, Thomas
[Wanker, Erich E.]
[Lehrach, Hans]
[Krobitsch, Sylvia]
Ataxin-2 and huntingtin interact with endophilin-A complexes to function in plastin-associated pathways
In: Human Molecular Genetics [14], 2893-2909
Journal Article
2005[Sarrazin, Christoph]
[Mihm, Ulrike]
[Herrmann, Eva]
[Welsch, Christoph]
Albrecht, Mario
[Sarrazin, Ulrike]
[Traver, Stella]
Lengauer, Thomas
[Zeuzem, Stefan]
Clinical significance of in vitro replication-enhancing mutations of the hepatitis C virus (HCV) replicon in patients with chronic HCV infection
In: The Journal of Infectious Diseases [192], 1710-1719
Journal Article
2005[Schreiber, Stefan]
[Rosenstiel, Philip]
Albrecht, Mario
[Hampe, Jochen]
[Krawczak, Michael]
Genetics of Crohn disease, an archetypal inflammatory barrier disease
In: Nature Reviews Genetics [6], 376-388
Journal Article
2005Stop sign IconSing, Tobias
Beerenwinkel, Niko
[Kaiser, Rolf]
[Hoffmann, Daniel]
[Däumer, Martin]
Lengauer, Thomas
Stop sign IconGeno2pheno[coreceptor]: a tool for predicting coreceptor usage from genotype and for monitoring coreceptor-associated sequence alterations
In: Proceedings of the 3rd European HIV Drug Resistance Workshop, -
Poster
2005Sing, Tobias
[Svicher, Valentina]
Beerenwinkel, Niko
[Ceccherini-Silberstein, Francesca]
[Däumer, Martin]
[Kaiser, Rolf]
[Walter, Hauke]
[Korn, Klaus]
[Hoffmann, Daniel]
[Oette, Mark]
[Rockstroh, Jürgen K.]
Fätkenheuer, Gerd
[Perno, Carlo-Federico]
Lengauer, Thomas
[Jorge, A]
[Torgo, L]
[Brazdil, P]
[Camacho, R]
[Gama, J]
Characterization of novel HIV Drug Resistance Mutations using clustering, multidimensional scaling and SVM-based feature ranking
In: Knowledge Discovery in Databases: PKDD 2005., 285-296
Proceedings Article
2005Steffen, Andreas
Kämper, Andreas
Lengauer, Thomas
Turner, A.P.F.FlexR - A new tool for predicting the structure of synthetic host-guest complexes
In: Synthetic Receptors 2005: Second World Congress on Synthetic Receptors, O7
Proceedings Article
2005[Svicher, Valentina]
[Ceccherini-Silberstein, Francesca]
Sing, Tobias
[Santoro, Maria Mercedes]
[Gori, C.]
Beerenwinkel, Niko
[Gago, F.]
[D'Arrigo, R.]
[Bellocchi, M. C.]
[Giannella, S.]
[Bertoli, A.]
[D'Arminio Monforte, A.]
[Antinori, A.]
[Perno, Carlo-Federico]
Additional Mutations in HIV-1 Reverse Transcriptase are Involved in the Highly Ordered Regulation of NRTI Resistance
In: Proceedings of the 3rd European HIV Drug Resistance Workshop, -
Proceedings Article
2005Stop sign Icon[Svicher, Valentina]
[Ceccherini-Silberstein, Francesca]
Sing, Tobias
[Santoro, Maria Mercedes]
[Gori, C.]
Beerenwinkel, Niko
[Gago, F.]
[D'Arrigo, R.]
[Bellochi, M.C.]
[Giannella, S.]
[Bertoli, A.]
[D'Arminio Monforte, A.]
[Antinori, A.]
[Perno, Carlo-Federico]
Stop sign IconA highly ordered network of HIV-1 RT mutations regulates the continuous escape from antiviral drugs
In: International Workshop in HIV Dynamics and Evolution, -
Proceedings Article
2005Stop sign IconTalwar, Priti
Lengauer, Thomas
Rahnenführer, Jörg
[Heinzle, Elmar]
[Velagapudi, VR]
[Wittmann, Christoph]
Stop sign IconTowards computational analysis of metabolic profiling data for protein function prediction.
In: Proceedings of the Yeast Systems Biology, 6th International Conference on Systems Biology (ICSB 2005), 1
Poster
2005Stop sign IconTalwar, Priti
Lengauer, Thomas
Rahnenführer, Jörg
[Wittmann, Christoph]
[Velagapudi, VR]
[Heinzle, Elmar]
Stop sign IconComputational Methods for Protein Function Prediction using Metabolomics Data
In: Proceedings of International Workshop on Systems Biology 2005, 1
Poster
2005[Ulmschneider, Sarah]
[Mueller-Vieira, Ursula]
[Klein, Christian D.]
Antes, Iris
Lengauer, Thomas
[Hartmann, Rolf W.]
Synthesis and Evaluation of Pyridylmethylene-tetrahydronaphthalenes and -indanes: Potent and Selective Inhibitors of Aldosterone Synthase (CYP11B2)
In: Journal of Medicinal Chemistry [48], 4489-4490
Journal Article
2005[Ulmschneider, Sarah]
[Mueller-Vieira, Ursula]
[Mitrenga, Markus]
[Hartmann, Rolf W.]
[Oberwinkler-Marchais, S]
[Klein, Christian D.]
[Bureik, M.]
[Bernhardt, R.]
Antes, Iris
Lengauer, Thomas
Synthesis and Evaluation of Imidazolylmethylenetetrahydronaphthalenes and Imidazolylmethyleneindanes: Potent Inhibitors of Aldosterone Synthase
In: Journal of Medicinal Chemistry [48], 1796-1805
Journal Article
2005[Valentonyte, Ruta]
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Albrecht, Mario
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[Gaede, Karoline I.]
[Franke, Andre]
[Haesler, Robert]
[Koch, Andreas]
Lengauer, Thomas
[Seegert, Dirk]
[Reiling, Norbert]
[Ehlers, Stefan]
[Schwinger, Eberhard]
[Platzer, Mathias]
[Krawczak, Michael]
[Müller-Quernheim, Joachim]
[Schürmann, Manfred]
[Schreiber, Stefan]
Sarcoidosis is associated with a truncating splice site mutation in BTNL2
In: Nature Genetics [37], 357-364
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2005[Van Duist, Marjan M.]
Albrecht, Mario
[Podswiadek, Marta]
[Giachino, Daniela]
Lengauer, Thomas
[Punzi, Leonardo]
[De Marchi, Mario]
A new CARD15 mutation in Blau syndrome
In: European Journal of Human Genetics [13], 742-747
Journal Article
2005[Voets, Marieke]
Antes, Iris
[Scherer, C]
[Mueller-Vieira, U.]
[Biemel, K.]
[Barrassin, C.]
[Marchais-Oberwinkler, S.]
[Hartmann, R. W.]
Heteroaryl-substituted naphthalenes and structurally modified derivatives: selective inhibitors of CYP11B2 for the treatment of congestive heart failure and myocardial fibrosis
In: Journal of Medicinal Chemistry [48], 6632-6642
Journal Article
2005Volkamer, AndreaAttachment IconImplementation of a method to filter
out compounds with toxic, reactive
and unsuitable functional groups
Universität des Saarlandes
Thesis - Bachelor thesis
2005Weiss, JuliaAttachment IconGenerating Frequency Profiles from Multiple
Structure Alignments
Universität des Saarlandes
Thesis - Bachelor thesis
2005[Wemmert, Silke]
[Ketter, Ralf]
Rahnenführer, Jörg
Beerenwinkel, Niko
[Strowitzki, Martin]
[Feiden, Wolfgang]
[Hartmann, Christian]
Lengauer, Thomas
[Stockhammer, Florian]
[Zang, Klaus D.]
[Meese, Eckart]
[Steudel, Wolf-Ingo]
[von Deimling, Andreas]
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Attachment IconPatients with high grade gliomas harboring delections of chromosomes 9p and 10q benefit from temozolomide treatment
In: Neoplasia [7], 883-893
Journal Article
2005Yalak, GarifAttachment IconAnalysis of Mutations in the Death Domains, Death Effector Domains, Caspase
Recruitment Domains, and Pyrin Domains
Universität des Saarlandes
Thesis - Bachelor thesis
2005Stop sign IconZhu, Hongbo
Domingues, Francisco S.
Sommer, Ingolf
Lengauer, Thomas
Stop sign IconAnalysis and prediction of protein-protein interaction types
In: 4th European Conference on Computational Biology (ECCB05), 1
Poster
32
Hide details for Publikationen im InternetPublikationen im Internet
2011Bogojeska, Jasmina[Shawe-Taylor, John]
[Zemel, Richard S.]
[Bartlett, Peter]
[Pereira, Fernando]
[Weinberger, Kilian Q.]
History distribution matching method for predicting effectiveness of HIV combination therapies
In: Neural Information Processing Systems (NIPS 2011), 424-432
Electronic Proceedings Article
2011[Codoner, Francisco]
[Pou, Christian]
Thielen, Alexander
[García, Federico]
[Delgado, Rafael]
[Dalmau, David]
[Álvarez-Tejado, Miguel]
[Ruiz, Lidia]
[Clotet, Bonaventura]
[Paredes, Roger]
Added value of deep sequencing relative to population sequencing in heavily pre-treated HIV-1-infected subjects
In: PLoS One [6], e19461,1-e19461,5
Electronic Journal Article
2011[Däumer, Martin]
[Kaiser, Rolf]
[Klein, Rolf]
Lengauer, Thomas
[Thiele, Bernhard]
Thielen, Alexander
Genotypic tropism testing by massively parallel sequencing: qualitative and quantitative analysis
In: BMC Medical Informatics and Decision Making [11], 30,1-30,8
Electronic Journal Article
2011[Ebrahimi, Mansou]
[Lakizadeh, Amir]
[Agha-Golzadeh, Esmaeil]
Ebrahimi, Mahdi
Prediction of Thermostability from Amino Acid Attributes by Combination of Clustering with Attribute Weighting: A New Vista in Engineering Enzymes
In: PLoS One [6], e23146,1-e23146,11
Electronic Journal Article
2011Emig, Dorothea
Sander, Oliver
Mayr, Gabriele
Albrecht, Mario
Structure collisions between interacting proteins
In: PLoS ONE [6], e19581,1-e19581,7
Electronic Journal Article
2011[Ruiz, Jeronimo C.]
[D'Afonseca, Vivian]
[Silva, Artur]
[Ali, Amjad]
[Pinto, Anne C.]
[Santos, Anderson R.]
[Rocha, Aryanne A. M. C.]
[Lopes, Debora O.]
[Dorella, Fernanda A.]
[Pacheco, Luis G. C.]
[Costa, Marcilia P.]
[Turk, Meritxell Z.]
[Seyffert, Nubia]
[Moraes, Pablo M. R. O.]
[Soares, Siomar C.]
[Almeida, Sintia S.]
[Castro, Thiago L. P.]
[Abreu, Vinicius A. C.]
[Trost, Eva]
Baumbach, Jan
[Tauch, Andreas]
[Schneider, Maria P. C.]
[McCulloch, John]
[Cerdeira, Louise T.]
[Ramos, Rommel T. J.]
[Zerlotini, Adhemar]
[Dominitini, Anderson]
[Resende, Daniela M.]
[Coser, Elisangela M.]
[Oliveira, Luciana M.]
[Pedrosa, Andre L.]
[Vieira, Carlos U.]
[Guimaraes, Claudia T.]
[Bartholomeu, Daniela C.]
[Oliveira, Diana M.]
[Santos, Fabricio R.]
[Rabelo, Elida Mara]
[Lobo, Francisco P.]
[Franco, Gloria R.]
[Costa, Ana Flavia]
[Castro, Ieso M.]
[Dias, Silvia Regina]
[Ferro, Jesus A.]
[Ortega, Jose Miguel]
[Paiva, Luciano V.]
[Goulart, Luiz R.]
[Almeida, Juliana Franco]
[Ferro, Maria Ines]
[Carneiro, Newton P.]
[Falcao, Paula R. K.]
[Grynberg, Priscila]
[Teixeira, Santuza M. R.]
[Brommonschenkel, Sergio]
[Oliveira, Sergio C.]
[Meyer, Roberto]
[Moore, Robert J.]
[Miyoshi, Anderson]
[Oliveira, Guilherme C.]
[Azevedo, Vaco]
Evidence for Reductive Genome Evolution and Lateral Acquisition of Virulence Functions in two Corynebacterium pseudotuberculosis strains
In: PLoS One [6], e18551
Electronic Journal Article
2011Saigo, Hiroto
Altmann, André
Bogojeska, Jasmina
Müller, Fabian
[Nowozin, Sebastian]
Lengauer, Thomas
Attachment IconLearning from past treatments and their outcome improves prediction of In Vivo response to anti-HIV therapy
In: Statistical Applications in Genetics and Molecular Biology [10], 1-32
Electronic Journal Article
2011Schelhorn, Sven-Eric
Mestre, Julián
Zotenko, Elena
Albrecht, Mario
Inferring physical protein contacts from large-scale purification data of protein complexes
In: Molecular & Cellular Proteomics [10], M110.004929,1-M110.004929,15
Electronic Journal Article
2011[Sierra, Saleta]
[Kaiser, Rolf]
[Lübke, Nadine]
Thielen, Alexander
[Schuelter, Eugen]
[Heger, Eva]
[Däumer, Martin]
[Reuter, Stefan]
[Esser, Stefan]
[Fätkenheuer, Gerd]
[Pfister, Herbert]
[Oette, Mark]
Lengauer, Thomas
Prediction of HIV-1 coreceptor usage (tropism) by sequence analysis using a genotypic approach
In: Journal of Visualized Experiments [58], e3264,1-e3264,9
Electronic Journal Article
2011[Ziller, Michael J.]
Müller, Fabian
[Liao, Jing]
[Zhang, Yingying]
[Gu, Hongcang]
Bock, Christoph
[Boyle, Patrick]
[Epstein, Charles B.]
[Bernstein, Bradley E.]
Lengauer, Thomas
[Gnirke, Andreas]
[Meissner, Alexander]
Genomic distribution and inter-sample variation of non-CpG methylation across human cell types
In: PLoS Genetics [17], e1002389,1-e1002389,15
Electronic Journal Article
2010Bozek, Katarzyna
Lengauer, Thomas
Positive selection of HIV host factors and the evolution of lentivirus genes
In: BMC Evolutionary Biology [10], 186,1-186,15
Electronic Journal Article
2010[Kamp, Christel]
[Wolf, Timo]
[Bravo, Ignacio G]
[Kraus, Benjamin]
[Krause, Birgit]
[Neumann, Britta]
[Winskowsky, Gudrun]
Thielen, Alexander
[Werner, Albrecht]
[Schnierle, Barbara S]
Decreased HIV diversity after allogeneic stem cell transplantation of an HIV-1 infected patient: a case report.
In: Virology Journal [7], 55,1-55,9
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2010[Kuroishi, Ayumu]
Bozek, Katarzyna
[Shioda, Tatsuo]
[Nakayama, Emi E.]
A single amino acid substitution of the human immunodeficiency virus type 1 capsid protein affects viral sensitivity to TRIM5 alpha.
In: Retrovirology [7], 58,1-58,10
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2010[Prosperi, Mattia C. F.]
[Rosen-Zvi, Michal]
Altmann, Andre
[Zazzi, Maurizio]
[Di Giambenedetto, Simona]
[Kaiser, Rolf]
[Schülter, Eugen]
[Struck, Daniel]
[Sloot, Peter]
[van de Vijver, David A.]
[Vandamme, Anne-Mieke]
[Sönnerborg, Anders]
Antiretroviral Therapy Optimisation without Genotype Resistance Testing: A Perspective on Treatment History Based Models
In: PLoS ONE [5], e13753,1-e13753,8
Electronic Journal Article
2010Roomp, Kirsten
Antes, Iris
Lengauer, Thomas
Predicting MHC class I epitopes in large datasets
In: BMC Bioinformatics [11], 90,1-90,11
Electronic Journal Article
2010Saigo, Hiroto
[Hattori, Masahiro]
[Kashima, Hisashi]
[Tsuda, Koji]
Reaction graph kernels predict EC numbers of unknown enzymatic reactions in plant secondary metabolism
In: BMC Bioinformatics [11], S31,1-S31,7
Electronic Journal Article
2010Weisser, Hendrik
Altmann, André
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[Incardona, Francesca]
[Struck, Daniel]
[Sönnerborg, Anders]
[Kaiser, Rolf]
[Zazzi, Maurizio]
[Tschochner, Monika]
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Lengauer, Thomas
Only Slight Impact of Predicted Replicative Capacity for Therapy Response Prediction
In: PLoSOne [5], e9044,1-e9044,10
Electronic Journal Article
2010[Wittkop, Tobias]
[Rahmann, Sven]
Baumbach, Jan
Efficient Online Transcription Factor Binding Site Adjustment by Integrating Transitive Graph Projection with MoRAine 2.0
In: Special Issue: 6th International Symposium on Integrative Bioinformatics, 117,1-117,11
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2010[Zazzi, Maurizio]
[Kaiser, Rolf]
[Sönnerborg, Anders]
[Struck, Daniel]
Altmann, Andre
[Prosperi, Mattia C. F.]
[Rosen-Zvi, Michal]
[Petroczi, Andrea]
[Peres, Yardena]
[Schülter, Eugen]
[Boucher, Charles]
[Brun-Vezinet, Francoise]
[Harigan, Richard]
[Morris, Lynn]
[Obermeier, Martin]
[Perno, Federico]
[Shafer, Robert]
[Vandamme, Anne-Mieke]
[van Laethem, Kristel]
[Wensing, Annemarie]
Lengauer, Thomas
[Incardona, Francesca]
Prediction of Response to Antiretroviral Therapy by Human Experts and by the EuResist Data-Driven Expert System (the EVE Study)
In: HIV Medicine [Early View], 1-8
Electronic Journal Article
2009Blankenburg, Hagen
Ramírez, Fidel
Büch, Joachim
Albrecht, Mario
DASMIweb: online integration, analysis and assessment of distributed protein interaction data
In: Nucleic Acids Research [37], W122-W128
Electronic Journal Article
2009Bozek, Kasia
[Relógio, Angela]
[Kielbasa, Szymon M.]
[Heine, Markus]
[Dame, Christof]
[Kramer, Achim]
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Regulation of clock-controlled genes in mammals.
In: PLoS One [4], e4882:1-e4882:12
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2009Bozek, Kasia
Thielen, Alexander
Sierra, Saleta
[Kaiser, Rolf]
Lengauer, Thomas
V3 loop sequence space analysis suggests different evolutionary patterns of CCR5- and CXCR4-tropic HIV.
In: PLoS One [4], e7387:1-e.7387:14
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2009Stop sign IconMcHardy, Alice C.
Adams, Ben
Stop sign IconThe role of genomics in tracking the evolution of influenza A virus
In: PLoS Pathog [5], e1000566
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2009[Zhang, Yingying]
[Rohde, Christian]
[Tierling, Sascha]
[Jurkowski, Tomasz P.]
Bock, Christoph
[Santacruz, Diana]
[Ragozin, Sergey]
[Reinhardt, Richard]
[Groth, Marco]
[Walter, Jörn]
[Jeltsch, Albert]
Attachment IconDNA methylation analysis of chromosome 21 gene promoters at single base pair and single allele resolution
In: PLoS Genetics [5], e1000438:1-e1000438:15
Electronic Journal Article
2008Feuerbach, Lars
Christopher, Bock
Halachev, Konstantin
Büch, Joachim
Lengauer, Thomas
[Meijer, Gerrit]
[Ried, Thomas]
[Giaretti, Walter]
[Hamilton, Peter]
Towards Comparative Epigenomics: A Software Toolkit For Cross-Species Epigenome Data Analysis
In: Abstracts of the 2nd MC-GARD Meeting, 230
Electronic Proceedings Article
2007[Kamradt, Jörn]
[Jung, Volker]
[Wahrheit, Kerstin]
Tolosi, Laura
Rahnenführer, Jörg
[Schilling, Martin]
[Walker, Robert]
[Davis, Sean]
[Stöckle, Michael]
[Meltzer, Paul]
[Wullich, Bernd]
Detection of Novel Amplicons in Prostate Cancer by Comprehensive Genomic Profiling of Prostate Cancer Cell Lines Using Oligonucleotide-Based ArrayCGH
In: PLoS ONE [2], e769
Electronic Journal Article
2007Schlicker, Andreas
Rahnenführer, Jörg
Albrecht, Mario
Lengauer, Thomas
Domingues, Francisco S.
Attachment IconGOTax: investigating biological processes and biochemical activities along the taxonomic tree
In: Genome Biology [8], R33.1-10
Electronic Journal Article
2006Bock, Christoph
[Paulsen, Martina]
[Tierling, Sascha]
[Mikeska, Thomas]
Lengauer, Thomas
[Walter, Jörn]
Attachment IconCpG Island Methylation in Human Lymphocytes Is Highly Correlated with DNA Sequence, Repeats, and Predicted DNA Structure
In: PLoS Genetics [2], 0243-0252
Electronic Journal Article
2006Sander, Oliver
Sommer, Ingolf
Lengauer, Thomas
Local protein structure prediction using discriminative models
In: BMC Bioinformatics [7], 1-13
Electronic Journal Article
2006Schlicker, Andreas
Domingues, Francisco S.
Rahnenführer, Jörg
Lengauer, Thomas
Attachment IconA new measure for functional similarity of gene products based on Gene Ontology
In: BMC Bioinformatics [7], 1-16
Electronic Journal Article
2006Sommer, Ingolf
[Toppo, Stefano]
Sander, Oliver
Lengauer, Thomas
[Tosatto, Silvio C. E.]
Improving the quality of protein structure models by selecting from alignment alternatives
In: BMC Bioinformatics [7], 1-11
Electronic Journal Article
2006Zhu, Hongbo
Domingues, Francisco S.
Sommer, Ingolf
Lengauer, Thomas
NOXclass: prediction of protein-protein interaction types
In: BMC Bioinformatics [7], 1-15
Electronic Journal Article
16
Hide details for DissertationenDissertationen
2011Bogojeska, JasminaAttachment IconStatistical Learning Methods for Bias-aware HIV Therapy Screening
Universität des Saarlandes
Thesis - PhD thesis
2011Bozek, KatarzynaAttachment IconAnalysis of HIV-host interaction on different scales.
Universität des Saarlandes
Thesis - PhD thesis
2011Emig, DorotheaNovel analysis approaches to context-dependent molecular networks
Universität des Saarlandes
Thesis - PhD thesis
2011Kunert, LarsMaximal Common Subgraph DAGs: Theory and Application to Virtual Screening in Drug Development
Universität des Saarlandes
Thesis - PhD thesis
2011Thielen, AlexanderGenotypic Analysis of HIV-1 Coreceptor Usage
Universität des Saarlandes
Thesis - PhD thesis
2010Altmann, AndréBioinformatical approaches to ranking of anti-HIV combination therapies and planning of treatment schedules
Universität des Saarlandes
Thesis - PhD thesis
2010Schlicker, AndreasAttachment IconOntology-based Similarity Measures and their Application in Bioinformatics
Universität des Saarlandes
Thesis - PhD thesis
2010Zhu, HongboCharacterization, classification and alignment of protein-protein interfaces
Universität des Saarlandes
Thesis - PhD thesis
2008Bock, ChristophComputational Epigenetics - Bioinformatic methods for epigenome prediction, DNA methylation mapping and cancer epigenetics
Universität des Saarlandes
Thesis - PhD thesis
2008Hartmann, ChristophModeling of Flexible Side Chains for Protein-Ligand Docking
Universität des Saarlandes
Thesis - PhD thesis
2008Maydt, JochenAnalysis of recombination in Molecular Sequence Data
Universität des Saarlandes
Thesis - PhD thesis
2008Sander, OliverStructural Descriptors for the Analysis of Protein Structure, Function, and Evolution
Universität des Saarlandes
Thesis - PhD thesis
2008Sing, TobiasModel-Based Anti HIV Therapy
Universität des Saarlandes
Thesis - PhD thesis
2008Steffen, AndreasComputational Approaches in Supramolecular Chemistry with a special Focus on Virtual Screening
Universität des Saarlandes
Thesis - PhD thesis
2008Talwar, PritiDevelopment of Computational Methods for Metabolic Network Analysis based on Metabolomics Data
Universität des Saarlandes
Thesis - PhD thesis
2006Albrecht, MarioCombining protein structure prediction with experiments and functional information
Universität des Saarlandes
Thesis - PhD thesis
357

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