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What and Who

Finding incompatible entities in medical definitions

Adam Grycner
Fachrichtung Informatik - Saarbrücken
PhD Application Talk

Master's Student
AG 1, AG 2, AG 3, AG 4, AG 5, SWS, RG1, MMCI  
Public Audience
English

Date, Time and Location

Monday, 25 February 2013
11:00
90 Minutes
E1 4
R024
Saarbrücken

Abstract

Recently, biomedical ontologies have been growing tremendously. They contain information about diverse concepts such as diseases, symptoms, and medications. These ontologies are rich in IS-A relations that form class hierarchies. However, incompatibility relationships are still very sparse.
We propose a method for automatically discovering incompatible medical concepts in text corpora. The approach is distantly supervised based on a seed set of incompatible concept pairs like symptoms or conditions that rule each other out. Two concepts are considered incompatible if their definitions match a template, and contain an antonym pair derived from WordNet, VerbOcean, or a hand-crafted lexicon. Our method creates templates from dependency parse trees of definitional texts, using seed pairs. The templates are applied to a text corpus, and the resulting candidate pairs are categorized and ranked by statistical measures.
Since experiments show that the results face semantic ambiguity problems, we further cluster the results into different categories. We applied this approach to the concepts in Unified Medical Language System, Human Phenotype Ontology, and Mammalian Phenotype Ontology. Out of 77,496 concepts with definitions, 1,958 pairs were detected as incompatible with an average precision of 0.80

Contact

IMPRS Office Team
0681 93251800
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Tags, Category, Keywords and additional notes

Stephanie Jörg, 02/22/2013 12:17
Stephanie Jörg, 02/22/2013 12:11 -- Created document.