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Comparing Methods for Finding Relevant Aberrations For Cancer

Violeta Ivanova
IMPRS-CS
Master Seminar Talk

IMPRS-CS Master student
AG 1, AG 3, AG 4, AG 5, SWS, RG1, MMCI  
Public Audience
English

Date, Time and Location

Wednesday, 20 May 2009
13:05
60 Minutes
E1 4
024
Saarbrücken

Abstract

Array Comparative Genomic Hybridization (aCGH) can reveal chromosomal aberrations in the tumor DNA.These amplifcations and deletions at the
DNA level are important in the pathogenesis of cancer. Finding the aberrations significant for cancer is vital for understanding the mechanisms of the disease
and for the further development of diagnostics, prognostics and drug design.
Different methods have been used developed in the attempt to solve this task, however the relative merits of these methods are not known. Our main goal
is to assess the various methods and to quantitatively compare how successful they are. This will be helpful for clinicians and also will give some direction in
the future development of methods for recurrent aberrations discovery.

Contact

imprs
06 81 93 25 225
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Stephanie Jörg, 05/18/2009 08:51
Stephanie Jörg, 05/08/2009 12:23
Stephanie Jörg, 05/08/2009 12:22 -- Created document.